HAMADA Junichiro 濱田潤一郎

Researcher Number	40253752
Affiliation (based on the past Project Information) *help	2015: 金沢大学, 医学系, 教授 2008 – 2013: Kanazawa University, 医学系, 教授 2005 – 2007: Kanazawa University, Department of Neurosurgery, Graduate School of Medical Science, Professor, 医学系研究科, 教授 2002 – 2004: Kumamoto University School of Medicine, Department of Neurosurgery, Assistant Professor, 医学部附属病院, 講師 1998: Kumamoto University, University Hospital, Assistant Professor, 医学部・附属病院, 助手 1996 – 1998: 熊本大学, 医学部附属病院, 助手 1994 – 1995: 熊本大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery / Neurosurgery Except Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery / Medical pharmacy / Medical systems
Keywords	Principal Investigator balloon expandable stent / liquid material / embolization / aneurysm / バルーン拡張型ステント / 脳動脈瘤 / 塞栓物質 / エタノール / LIPOSOME / NITROSOUREAS … More / INTRATHECAL CHEMOTHERAPY / SUBARACHNOID DISSEMINATION / MALIGNANT GLIOMAS / ACNU / 髄腔内潅流化学療法 / 神経膠腫(グリオーマ) / 髄液腔内潅流療法 / グリオーマ / リポソーム / BCNU / 悪性脳腫瘍 / リボソーム / ニトロソウレア / 髄腔内化学療法 / 髄腔内播種 / 悪性グリオーマ / 大槽内注入 / 脳血管攣縮 / 血栓溶解 / 大槽 / マイクロアレイ / プロテオーム / 脳神経疾患 / マイクロキャリーア / 粒子塞栓物質 / 塞栓術 … More Except Principal Investigator ischemia / Akt / 海馬 / 脳虚血 / BiP / hypoxia / ER stress / CHOP / apoptosis / vanadate / 脳梗塞 / CREB / PHOSPHORYLATION / HIPPOCAMPUS / 燐酸化反応 / リン酸化反応 / STEP / GABA / Striatum / N-methyl-D-aspartate / Cerebral ischemia / 細胞内情報伝達 / NF2 / NF1 / MCP-1 / PDGF / Bip / 線条体 / アポトーシス / 小胞体ストレス / ERK / MCA occlusion / neuronal stem cell / ischemic cell death / 神経幹細胞 / バナジン酸 / Embolization / Aneurysm / Interventional surgery / Vasospasm / Urokinase / Subarachnoid hemorrhage / 動脈瘤塞栓術 / 破裂脳動脈瘤 / 脳血管内治療 / 脳血管攣縮 / ウロキナーゼ / くも膜下出血 / ISCHEMIC TOLERANCE / CRE-decoy / 脳虚血耐性 / NEURONAL CELL DEATH / TAR FACTOR / ISCHEMIA / 一過性脳虚血 / タウ因子 / Tyrosine-phosphatase / Calcium signal / Transplantation / カルシウム / 神経細胞死 / Neuronal development / Tyrosine dephosphorylation / Second messenger / GABA agonist / NMDA receptor / Phoaphatase / STFP / Ca^<2+>-signal / transplantation / SURAMIN / TRAPIGIL / GLIOMA / 遺伝子 / 増殖因子 / 脳腫瘍 / Neurofibromatosis / グリオーマ細胞 / スラミン / トラピジ-ル / グリオーマ / 脳疾患 / 細胞内情報伝達系 / 輸送担体 / Pharmacoproteomics / 標的絶対定量プロテオミクス / P-glycoprotein / P-糖タンパク / 病態 / 可塑性 / P-糖蛋白 / 定量プロテオミクス / リン酸化 / トランスポーター / 血液脳関門 / 摩擦 / 手術 / 鉗子 / 脳・神経 / 共焦点顕微鏡 / 悪性グリオーマ / 血管新生 / 腫瘍浸潤 / 細胞性浮腫 / 血管平滑筋 / コラゲン / in situ hybridization / 免疫組織化学 / 脳動脈瘤 Less

膠芽腫に対するチロシンキナーゼ阻害剤を使用した個別化化学療法の基礎基盤の構築Principal Investigator
- Principal Investigator
  
  濱田潤一郎
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
Clarification of molecular mechanisms of the blood-brain barrier plasticity based on quantitative targeted absolute proteomics
- Principal Investigator
  
  Terasaki Tetsuya
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tohoku University
Intrathecal infusion of thrombolytic agent and/or vasodilator from cisterna magna for prevention and therapy of angiospasmPrincipal Investigator
- Principal Investigator
  
  HAMADA Jun-ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kanazawa University
Intraoperative diagnose and remove system for brain tumors using confocal microscopy probe and friction detecting forceps
- Principal Investigator
  
  YONEYAMA Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
Research of function of aquaporins in malignant glioma and novel therapeutic strategy with their inhibition
- Principal Investigator
  
  HAYASHI Yasuhiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kanazawa University
膜蛋白のプロテオーム解析による神経膠芽腫浸潤関連分子の同定と機能解析Principal Investigator
- Principal Investigator
  
  濱田潤一郎
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kanazawa University
Research of aneurysmal embolization using liquid material and balloon-expandable stentPrincipal Investigator
- Principal Investigator
  
  HAMADA Jun-ichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kanazawa University
  Kumamoto University
Role of ER-stress on ischemic neuronal cell death
- Principal Investigator
  
  YANO Shigetoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Microcatheter Intrathecal Urokinase Infusion In to Cistema Magna for Prevention of Cerebral Vasospasm
- Principal Investigator
  
  KAI Yutaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Treatment for acute/chronic ischemic neuronal injury using vanadate
- Principal Investigator
  
  MORIOKA Motohiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
The role of phosphorylation reaction of tau factor in ischemic neuronal cell death
- Principal Investigator
  
  MORIOKA Motohiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Research for the mechanism of ischemic tolerance in neuronal cells
- Principal Investigator
  
  YANO Shigetoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Study on the ischemia-induced neuronal injuries with special reference to alterations in the intracellular signaling cascades.
- Principal Investigator
  
  GOTO Satoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
新しい粒子塞栓物質の基礎的研究と臨床応用Principal Investigator
- Principal Investigator
  
  濱田潤一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
脳動脈瘤の増大、破裂機序:細胞外マトリックスの変動に関する研究
- Principal Investigator
  
  永廣信治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Establishment of the New Approach to the Treatment of Malignant Glioma
- Principal Investigator
  
  USHIO Yukitaka
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  KUMAMOTO UNIVERSITY
INTRATHECAL CHEMOTHERAPY AGAINST SUBARACHNOID DISSEMINATION OF MALIGNANT BRAIN TUMORSPrincipal Investigator
- Principal Investigator
  
  HAMADA Junichiro, 河内正人
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  KUMAMOTO UNIVERSITY

All 2009 2008 2007 2004 2003 2000

All Journal Article Presentation

[Journal Article] Potential Therapeutic Effect of Glycogen Synthase Kinase 3β Inhibition against Human Glioblastoma.2009
- Author(s)
  宮下勝吉, 濱田潤一郎, ら
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages: 887-897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659416
[Journal Article] Incidence and early prognosis of aneurysmal subarachnoid hemorrhage in Kumamoto Prefecture, Japan.2004
- Author(s)
  Hamada, J., Morioka, M., Yano, S., Kai, Y., Ushio, Y.
- Journal Title
  
  Neurosurgery 54
  
  Pages: 31-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Brain stem venous congestion due to dural arteriovenous fistulas of the cavernous sinus.2004
- Author(s)
  Kai, Y., Hamada J.-I., Morioka M., Yano S., Ushio
- Journal Title
  
  Acta Neurochir(Wien) 146
  
  Pages: 1107-1112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Contribution of angiotensin-converting enzyme and angiotensin II to ischemic stroke : Their role in the formation of stable and unstable carotid atherosclerotic plaques.2004
- Author(s)
  Morioka, M., Hamada, J., Hashiguchi, A., Hasegawa, Y., Todaka, T., Yano, S., Kai, Y., Miura, M., Fujioka, S, Ushio, Y.
- Journal Title
  
  Surgical Neurology 62
  
  Pages: 292-303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] The post-ischemic administration of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1h-indazole dihydrochloride 3.5 hydrate(DY-9760e), a novel calmodulin antagonist, prevents delayed neuronal death in gerbil hippocampus.2004
- Author(s)
  Hashiguchi, A., Yano, S., Morioka, M., Hamada, J., Shirasaki Y, Kochi M, Fukunaga, K.
- Journal Title
  
  J Pharmacol Sci 96
  
  Pages: 65-72
- NAID
  10014166332
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Incidence and early prognosis of aneurysmal subarachnoid hemorrhage in Kumamoto Prefecture, Japan.2004
- Author(s)
  Hamada J. et al.
- Journal Title
  
  Neurosurgery 54
  
  Pages: 31-73
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP.2004
- Author(s)
  Tajiri, S., Oyadomari, S., Yano, S., Morioka, M., Gotoh, T., Hamada, J., Ushio, Y., Mori, M.
- Journal Title
  
  Cell Death and Differentiation 11
  
  Pages: 403-415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus.2004
- Author(s)
  Hashiguchi, A., Yano, S., Morioka, M., Hamada, J., Ushio, Y., Takeuchi, Y., Fukunaga, K.
- Journal Title
  
  J of Cerebral Blood Flow and Metabolism 24
  
  Pages: 271-279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Incidence and early prognosis of aneurysmal subarachnoid hemorrhage in Kumamoto Prefecture, Japan.2004
- Author(s)
  Hamada J.et al.
- Journal Title
  
  Neurosurgery 54
  
  Pages: 31-73
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Contribution of angiotensin-converting enzyme and angiotensin II to ischemic stroke : their role in the formation of stable and unstable carotid atherosclerotic plaques.2004
- Author(s)
  Morioka M, Hamada J et al.
- Journal Title
  
  Surg Neurol 62(4)
  
  Pages: 301-303
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Effect on Cerebral Vasospasm of Coil Embolization Followed by Microcatheter Intrathecal Urokinase Infusion Into the Cisterna Magna. A Prospective Randomized Study.2003
- Author(s)
  Hamada JI, Kai Y, Morioka M, Yano S, Mizuno T, Hirano T, Kazekawa K, Ushio Y
- Journal Title
  
  Stroke 34
  
  Pages: 2549-2554
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591533
[Journal Article] CREB is required for acquisition of ischemic tolerance in gerbil hippocampal CA1 region.2003
- Author(s)
  Hara T, Hamada J, Yano S et al.
- Journal Title
  
  J Neurochem 86(4)
  
  Pages: 805-814
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591448
[Journal Article] Intrathecal urokinase infusion through a microcatheter into the cisterna magna to prevent cerebral vasospasm : experimental study in dogs.2003
- Author(s)
  Mizuno T, Hamada J, Kai Y, Todaka T, Morioka M, Ushio Y
- Journal Title
  
  AJNR Am J Neuroradiol 24
  
  Pages: 613-618
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591533
[Journal Article] Effect on cerebral vasospasm of coil embolization followed by microcatheter intrathecal urokinase infusion into the cisterna magna : a prospective randomized study2003
- Author(s)
  Hamada J. et al.
- Journal Title
  
  Stroke 34
  
  Pages: 2549-2554
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591533
[Journal Article] Effect on cerebral vasospasm of coil embolization followed by microcatheter intrathecal urokinase infusion into the cistema magna : a prospective randomized study2003
- Author(s)
  Hamada J.et al.
- Journal Title
  
  Stroke 34
  
  Pages: 2549-2554
- Data Source
  KAKENHI-PROJECT-15591533
[Journal Article] Single blood injection into the ventral cisterna magna through a microcatheter for the production of delayed cerebral vasospasm : experimental study in dogs.2003
- Author(s)
  Mizuno T, Hamada J, Kai Y, Todaka T, Morioka M, Ushio Y
- Journal Title
  
  AJNR Am J Neuroradiol 24
  
  Pages: 608-612
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591533
[Journal Article] Multimodal treatment of ruptured dissecting aneurysms of the vertebral artery during the acute stage.2003
- Author(s)
  Hamada, J., Kai, Y., Morioka, M., Yano, S., Todaka, T, Ushio, Y.
- Journal Title
  
  Journal of Neurosurgery 99
  
  Pages: 960-966
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591534
[Journal Article] Microcatheter intrathecal urokinase infusion into cisterna magna for prevention of cerebral vasospasm : preliminary report.2000
- Author(s)
  Hamada J, Mizuno T, Kai Y, Morioka M, Ushio Y
- Journal Title
  
  Stroke 31
  
  Pages: 2141-2148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591533
[Presentation] Possible participation of aquaporin-1 in aerobic glycolysis and perivascular cell invasion of glioma cells2008
- Author(s)
  Hayashi Y, Edwards NA, Proescholdt MA, Hamada J, Oldfield EH, Merrill MJ
- Organizer
  Congress of Neurological Surgeons
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2008-09-22
- Data Source
  KAKENHI-PROJECT-19591666
[Presentation] Possible participation of aquaporin-1 in aerobic glycolysis and perivascular cell invasion of glioma cells2008
- Author(s)
  Yasuhiko Hayashi, Nancy Edwards, Martin Proescholdt, Jun-ichiro Hamada, Edward Oldfield, Marsha Merrill
- Organizer
  2008 Annual Meeting of Congress of Neurological Surgeons
- Place of Presentation
  Orland, FL, USA
- Data Source
  KAKENHI-PROJECT-19591666
[Presentation] 悪性グリオーマのperivascular cell infiltration におけるAQP-1 の関与2007
- Author(s)
  林康彦、吉田優也、中田光俊、喜多大輔、濱田潤一郎、岡本浩昌、Martin Proescholdt, Nancy Edwards, Marsha Merrill, Edward Oldfield
- Organizer
  第12回グリア研究会
- Place of Presentation
  名古屋
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19591666
[Presentation] 悪性グリオーマにおけるAQP1による細胞性浮腫調節機構2007
- Author(s)
  林康彦、吉田優也、濱田潤一郎、岡本浩昌、Martin Proescholdt, Nancy Edwards,Edward Oldfield, Marsha Merril
- Organizer
  第2 回脳浮腫・頭蓋内圧フォーラム
- Place of Presentation
  東京
- Year and Date
  2007-06-30
- Data Source
  KAKENHI-PROJECT-19591666

1. USHIO Yukitaka (20028583)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. MORIOKA Motohiro (20295140)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
3. YANO Shigetoshi (60332871)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
4. GOTO Satoshi (50240916)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
5. NISHI Tohru (00264309)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. KAI Yutaka (30322308)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
7. 永廣信治 (60145315)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. HAYASHI Yutaka (90262568)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. HAYASHI Yasuhiko (50324124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. UCHIYAMA Naoyuki (80293364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KURATSU Junichi (20145296)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 河内正人 (70178218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. YONEYAMA Takeshi (30175020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. WATANABE Tetsuyou (80363125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAGAWA Hiroyuki (40251938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Terasaki Tetsuya (60155463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TACHIKAWA Masanori (00401810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKADA Mitsutoshi (20334774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. WATANABE Michitoshi (40303127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. UCHIDA Yasuo (70583590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKESHIMA Hideo (70244134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MORI Masataka (40009650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 毛利正直 (60377413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 渡邉卓也 (90399775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAMADA Junichiro 濱田 潤一郎

Research Projects

Research Products

Co-Researchers

膠芽腫に対するチロシンキナーゼ阻害剤を使用した個別化化学療法の基礎基盤の構築Principal Investigator

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Intrathecal infusion of thrombolytic agent and/or vasodilator from cisterna magna for prevention and therapy of angiospasmPrincipal Investigator

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膜蛋白のプロテオーム解析による神経膠芽腫浸潤関連分子の同定と機能解析Principal Investigator

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Research of aneurysmal embolization using liquid material and balloon-expandable stentPrincipal Investigator

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新しい粒子塞栓物質の基礎的研究と臨床応用Principal Investigator

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Principal Investigator

HAMADA Junichiro 濱田潤一郎