ARATANI Satoko 荒谷聡子

… Alternative Names

荒谷聡子アラタニサトコ

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Researcher Number	40387064
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2019: 東京医科大学, 医学部, 講師 2011 – 2014: 東京医科大学, 医学部, 助教 2010 – 2011: 東京医科大学, 医学部, ポストドクター 2009: 東京医科大学, 医学部, 助教 2009: 聖まマリアンナ医科大学, 医学部, 研究員 2009: 聖マリアンナ医科大学, 医学部, 研究員 2005: 聖マリアンナ医科大学, 難病治療研究センター, 研究員
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Pathological medical chemistry / Collagenous pathology/Allergology Except Principal Investigator Biological Sciences / 膠原病・アレルギー・感染症内科学 / Pathological medical chemistry / Collagenous pathology/Allergology
Keywords	Principal Investigator 視床下部 / 転写後修飾 / PADI4 / シトルリン化 / Synoviolin / 関節リウマチ / ユビキチン化 / 脳神経疾患 / HPVワクチン / モデルマウス … More / HANS / ミトコンドリア / 小胞体ストレス / 疼痛 / 線維筋痛症 / シノビオリン / リウマチ学 … More Except Principal Investigator シノビオリン / 関節リウマチ / 転写制御 / E3ユビキチンリガーゼ / 滑膜細胞増殖 / 滑膜細胞 / 小胞体関連分解 / ユビキチン化 / ノックアウトマウス / 基質 / アポトーシス / タンパク質分解 / 遺伝子改変動物 / サルコペニア / 骨代謝 / 動物 / タンパク質 / 遺伝子 / T細胞 / 生化学的手法 / 化合物 / コンディショナルノックアウトマウス / 分泌 / 滑膜細胞細胞 / サイトカイン / 肝硬変 / コンディショナルノックアウト / 慢性炎症 / 分泌タンパク質 / 線維化 / 小胞体ストレス / 転写複合体 / ESコビキチンリガーゼ / 遺伝子改変マウス / 造血 / 小胞体 Less

Improvement of vaccines against human papilloma viruses and evaluation of treatments of human papillomavirus vaccination-associated neuro-immunopathic syndrome with pathological model micePrincipal Investigator
- Principal Investigator
  
  Aratani Satoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical University
Involvement of Synoviolin in Muscle metabolism via two distinct pathways
- Principal Investigator
  
  Nakajima Toshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical University
The regulation mechanisms of chronic pain via ER-stress pathway in fibromyalgiaPrincipal Investigator
- Principal Investigator
  
  Satoko Aratani
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tokyo Medical University
The study of bone destruction mechanism of rheumatoid arthritis by synoviolin
- Principal Investigator
  
  YAGISHITA Naoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  St. Marianna University School of Medicine
Relationship of post-translational modifications in RA synoviocytesPrincipal Investigator
- Principal Investigator
  
  SATOKO Aratani
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Medical University
The functions of the post-translational modifications in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  ARATANI Satoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Medical University
二元的アポトーシス制御因子シノビオリンを標的としたがん研究
- Principal Investigator
  
  中島利博
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Choju Medical Institute, Fukushimura Hospital.
シノビオリンの二方向性シグナル制御の生物学的意義
- Principal Investigator
  
  中島利博
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Choju Medical Institute, Fukushimura Hospital.
Integrated study on implication of Synoviolin in multiprocesses of rheumatoid arthritis.
- Principal Investigator
  
  NAKAJIMA Toshihiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Medical University
  Choju Medical Institute, Fukushimura Hospital.
滑膜細胞の小胞体機能亢進症 -関節リウマチの新しい病態モデルの提唱に向けた研究-
- Principal Investigator
  
  NAKAJIMA Toshihiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine

[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis2017
- Author(s)
  Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T
- Total Pages
  155
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-26461476
[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis　Synoviolin is a novel pathogenic factor of arthropathy and chronic inflammation.2016
- Author(s)
  edited by Lazaros I. Sakkas　Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T.
- Total Pages
  151
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] What occurs in human papilloma virus vaccination-associated neuro-immunopathic syndrome (HANS)? : implications of previous animal model studies2018
- Author(s)
  Aratani S, Kuroiwa Y, Fujita H, Usui C, Yokota S, Nakamura I, Nishioka K, Nakajima T
- Journal Title
  
  The Autonomic Nervous System
  
  Volume: 55 Pages: 915-919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08671
[Journal Article] Identification of the inhibitory activity of E3 ligase Syvn1 in walnut extract.2018
- Author(s)
  Fujita H, Aratani S, Yagishita N, Nishioka K, Nakajima T.
- Journal Title
  
  Mol. Med. Rep
  
  Volume: 8(6) Pages: 5701-5708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08671
[Journal Article] Identification of the inhibitory activity of E3 ligase Syvn1 in walnut extract.2018
- Author(s)
  Fujita H, Aratani S, Yagishita N, Nishioka K, Nakajima T.
- Journal Title
  
  Mol. Med. Rep.
  
  Volume: 8(6) Pages: 5701-5708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] What occurs in human papilloma virus vaccination-associated neuro-immunopathic syndrome (HANS)? : implications of previous animal model studies2018
- Author(s)
  Aratani S, Kuroiwa Y, Fujita H, Usui C, Yokota S, Nakamura I, Nishioka K, Nakajima T
- Journal Title
  
  The Autonomic Nervous System (自律神経 @日本自律神経学会)
  
  Volume: 55(3) Pages: 165-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] 線維筋痛症の病態・病因2018
- Author(s)
  荒谷　聡子、中島　利博
- Journal Title
  
  日本臨牀
  
  Volume: 76 (11) Pages: 1921-1926
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] The NRF2-PGC-1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, Synoviolin, in a cecal ligation/perforation -induced septic mouse model.2018
- Author(s)
  Ishida Y, Fujita H, Aratani S, Chijiiwa M, Taniguchi N, Yokota M, Ogihara Y, Uoshima N, Nagashima F, Uchino H, Nakajima T.
- Journal Title
  
  Mol. Med. Rep.
  
  Volume: 18(2) Pages: 2467-2475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08671
[Journal Article] The NRF2-PGC-1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, Synoviolin, in a cecal ligation/perforation -induced septic mouse model.2018
- Author(s)
  Ishida Y, Fujita H, Aratani S, Chijiiwa M, Taniguchi N, Yokota M, Ogihara Y, Uoshima N, Nagashima F, Uchino H, Nakajima T.
- Journal Title
  
  Mol. Med. Rep.
  
  Volume: 18(2) Pages: 2467-2475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] 線維筋痛症の病態・病因2018
- Author(s)
  荒谷　聡子、中島　利博
- Journal Title
  
  日本臨牀
  
  Volume: 76 (11) Pages: 1921-1926
- Data Source
  KAKENHI-PROJECT-17K08671
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI42017
- Author(s)
  Aratani S、Fujita H、Yagishita N、Yamano 、Okubo Y、Nishioka K、Nakajima T
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 16 Issue: 6 Pages: 9203-9209
- DOI
  10.3892/mmr.2017.7764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08671, KAKENHI-PROJECT-17K08675
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI4.2017
- Author(s)
  Aratani S, Fujita H, Yagishita N, Yamano Y, Okubo Y, Nishioka K, Nakajima T
- Journal Title
  
  Mol. Med. Rep
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI42017
- Author(s)
  Aratani S, Fujita H, Yagishita N, Yamano Y, Okubo Y, Nishioka K, Nakajima T
- Journal Title
  
  Mol. Med. Rep
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461476
[Journal Article] A Study of Brain Metabolism in Fibromyalgia by Positron Emission Tomography2017
- Author(s)
  Usui C, Soma T, Hatta K, Aratani S, Fujita H, Nishioka K, Machida Y, Kuroiwa Y, Nakajima T, Nishioka K
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry.
  
  Volume: 75 Pages: 120-127
- DOI
  10.1016/j.pnpbp.2017.01.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-17K08675
[Journal Article] Murine hypothalamic destruction with vascular cell apoptosis subsequent to combined administration of human papilloma virus vaccine and pertussis toxin2016
- Author(s)
  Aratani S, Fujita H, Kuroiwa Y, Usui C, Yokota S, Nakamura I, Nishioka K, Nakajima T
- Journal Title
  
  Sci.Rep
  
  Volume: 6 Issue: 1 Pages: 36943-36943
- DOI
  10.1038/srep36943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-15K15091
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI42016
- Author(s)
  *Aratani S, Fujita H, Yagishita N, Yamano Y, Okubo Y, Nishioka K, Nakajima T
- Journal Title
  
  Mol. Med. Rep. in press
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461478
[Journal Article] A case of fibromyalgia involving pain throughout the body treated with site-specific targeted pain control.2016
- Author(s)
  Nakajima F, Aratani S, Fujita H, Nakatani K, Makita K, Nakajima T
- Journal Title
  
  Springerplus
  
  Volume: 5 Issue: 1 Pages: 1027-1027
- DOI
  10.1186/s40064-016-2572-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26461478, KAKENHI-PROJECT-15K15091
[Journal Article] Mitochondrial Ubiquitin Ligase Activator of NF-κB (MULAN) regulates NF-κB signaling in ER stress-stimulated cells.2016
- Author(s)
  Fujita H, Aratani S, Fujii R, Yamano Y, Yagishita N, Araya N, Izumi T, Azakami K, Hasegawa D, Nishioka K and Nakajima T
- Journal Title
  
  Int J Mol Med.
  
  Volume: 37 Issue: 6 Pages: 1611-1618
- DOI
  10.3892/ijmm.2016.2566
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-25461490, KAKENHI-PROJECT-26461478
[Journal Article] Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia.2015
- Author(s)
  Nakajima F, Aratani S, Fujita H, Yagishita N, Ichinose S, Makita K, Setoguchi Y, Nakajima T.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 35 Issue: 1 Pages: 110-6
- DOI
  10.3892/ijmm.2014.1984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26461478
[Journal Article] The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.2015
- Author(s)
  Fujita H, Yagishita N, Aratani S, Saito-Fujita T, Morota S, Yamano Y, Hansson MJ, Inazu M, Kokuba H, Sudo K, Sato E, Kawahara K, Nakajima F, Hasegawa D, Higuchi I, Sato T, Araya N, Usui C, Nishioka K, Nakatani Y, Maruyama I, Usui M, Hara N, Uchino H, Elmer E, Nishioka K, Nakajima T.
- Journal Title
  
  EMBO J.
  
  Volume: 34 Issue: 8 Pages: 1042-55
- DOI
  10.15252/embj.201489897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-26670793, KAKENHI-PROJECT-26461478, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293385
[Journal Article] Effects of xenon irradiation of the stellate ganglion region on fibromyalgia2015
- Author(s)
  Nakajima F, Komoda A, Aratani S, Fujita H, Kawate M, Nakatani K, Akiyama M, Makita K, Nakajima T.
- Journal Title
  
  Journal of Physical Therapy Science
  
  Volume: 27 Issue: 1 Pages: 209-212
- DOI
  10.1589/jpts.27.209
- NAID
  130004835113
- ISSN
  0915-5287, 2187-5626
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26461476
[Journal Article] Vulnerability to traumatic stress in fibromyalgia patients : 19 months follow-up after the Great East Japan Disaster2013
- Author(s)
  Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 15(5) Issue: 5
- DOI
  10.1186/ar4310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-24791006, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25670295
[Journal Article] The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale : reliability and validity2013
- Author(s)
  Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Itoh K, Yamano Y, Nakamura H, Nakajima T, Nishioka K
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23(5) Issue: 5 Pages: 846-850
- DOI
  10.1007/s10165-012-0759-x
- NAID
  10031201138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-23659502, KAKENHI-PROJECT-24791006, KAKENHI-PROJECT-25670295
[Journal Article] RING finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis2012
- Author(s)
  Yagishita N, Aratani S, Leach C, Amano T, Yamano Y, Nakatani K, Nishioka K, Nakajima T
- Journal Title
  
  Int J Mol Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] RING finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis2012
- Author(s)
  Yagishita N, Aratani S, Leach C, Amano T, Yamano Y, Nakatani K, Nishioka K, Nakajima T
- Journal Title
  
  Int J Mol Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale : reliability and validity2012
- Author(s)
  臼井千恵、中島利博, 他9名
- Journal Title
  
  Mod.Rheumatol.
  
  Volume: 20 Issue: 1 Pages: 40-44
- DOI
  10.1007/s10165-011-0462-3
- NAID
  10030206754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-21500629, KAKENHI-PROJECT-22590221, KAKENHI-PROJECT-22659121, KAKENHI-PROJECT-22790947, KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-23659176, KAKENHI-PROJECT-24791006, KAKENHI-PROJECT-25305032
[Journal Article] The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale : reliability and validity2012
- Author(s)
  Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Ito K, Yamano Y, Nakamura H, Nakajima T, Nishioka K
- Journal Title
  
  Mod Rheumatol
  
  Volume: 20 Pages: 40-44
- NAID
  10030206754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis.2012
- Author(s)
  Yagishita N., Aratani S., Leach C., Amano T., Yamano Y., Nakatani K., Nishioka K. and Nakajima T
- Journal Title
  
  Int. J. Mol. Med
  
  Volume: 30 Issue: 6 Pages: 1281-1286
- DOI
  10.3892/ijmm.2012.1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659176, KAKENHI-PROJECT-23659502, KAKENHI-PROJECT-24791006
[Journal Article] Overexpression of SPACIA1/SAAL1, a new gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans2011
- Author(s)
  Sato T, Fujii R, Konomi K, Yagishita N, Aratani S, Araya N, Aono H, Yudoh K, Suzuki N, Beppu M, Yamano Y, Nishioka K, Nakajima T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 3833-3842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease2011
- Author(s)
  荒谷聡子, 他14名
- Journal Title
  
  Antiviral Therapy
  
  Volume: 16 Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease2011
- Author(s)
  Araya N, Takahashi K, Sato T, Nakamura T, Sawa C, Hasegawa D, Ando H, Aratani S, Yagishita N, Fujii R, Oka H, Nishioka, K, Nakajima T, Mori N, Yamano Y
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes2011
- Author(s)
  Sato T, Konomi K, Fujii R, Aono H, Aratani S, Yagishita N, Araya N, Yudoh K, Beppu M, Yamano Y, Nishioka K, Nakajima T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Issue: 1 Pages: 221-22
- DOI
  10.1136/ard.2009.118620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833, KAKENHI-PROJECT-23659176
[Journal Article] Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes2011
- Author(s)
  Sato T, Konomi K, Fujii R, Aono H, Aratani S, Yagishita N, Araya N, Yudoh K, Beppu M, Yamano Y, Nishioka K, Nakajima T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Pages: 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease2011
- Author(s)
  Araya N, Takahashi K, Sato T, Nakamura T, Sawa C, Hasegawa D, Ando H, Aratani S, Yagishita N, Fujii R, Oka H, Nishioka K, Nakajima T, Mori N, Yamano Y
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 89-98
- URL
  http://www.intmedpress.com/serveFile.cfm?sUID=eda7bacc-605e-4dd6-b2aa-f62abc29e554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes2011
- Author(s)
  荒谷聡子, 他11名
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 70 Pages: 221-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.2010
- Author(s)
  荒谷聡子, 他18名
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koike J, Tadokoro M, Suzuki N, Nagata K, Senoo H, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 5 Issue: 10 Pages: e13590-e13590
- DOI
  10.1371/journal.pone.0013590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koide J, Tadokoro M, Suzuki N, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One 5(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koike J, Tadokoro M, Suzuki N, Nagata K, Senoo H, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 5(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790947
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum. 60(1)
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Abnormally high levels of virusinfected IFN-gamma+CCR4+CD4+CD25+T cells in a retrovirus-associated neuroinflammatory disorder2009
- Author(s)
  Yamano Y, Araya N, Sato T, Utsunomiya A, Azakami K, Hasegawa D, Izumi T, Fujita H, Aratani S, Yagishita N, Fujii R, Nishioka K, Jacobson S, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 4 Issue: 8 Pages: e6517-e6517
- DOI
  10.1371/journal.pone.0006517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009
- Author(s)
  Araya N, Arimura H, Kawahara K, Yagishita N, Ishida J, Fujii R, Aratani S, Fujita H, Sato T, Yamano Y, Higuchi I, Osame M, Nishioka K, Fukamizu A, Arimura K, Maruyama I, Nakajima T.
- Journal Title
  
  Int J Mol Med
  
  Volume: 24 Issue: 05 Pages: 605-611
- DOI
  10.3892/ijmm_00000271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-23659176
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 60 Issue: 1 Pages: 63-72
- DOI
  10.1002/art.24178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders2009
- Author(s)
  Azakami K, Sato T, Araya N, Utsunomiya A, Kubota R, Suzuki K, Hasegawa D, Izumi T, Fujita H, Aratani S, Fujii R, Yagishita N, Kamijuku H, Kanekura T, Seino K, Nishioka K, Nakajima T, Yamano Y
- Journal Title
  
  Blood
  
  Volume: 114 Issue: 15 Pages: 3208-3321
- DOI
  10.1182/blood-2009-02-203042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] MLE activates transcription via the minimal transactivation domain in Drosophila2008
- Author(s)
  Aratani S, Kageyama Y, Nakamura A, Fujita H, Fujii R, Nishioka K, Nakajima T
- Journal Title
  
  Int J Mol Med
  
  Volume: 21 Pages: 469-476
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/18360693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Increased prevalence of group Aβ-hemolytic streptococcus among an ethnic population in Kyrgyzstan detected by the rapid antigen detection test2008
- Author(s)
  Omurzakova OA, Yamano Y, Sato T, Izumi T, Azakami K, Hasegawa D, Fujii R, Yagishita N, Aratani S, Kabaeva ZS, Mirrakhimov MM, Kami M, Maruyama I, Osame M, Yokota S, Nishioka K, Nakajima T
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 1 Pages: 869-874
- DOI
  10.3892/mmr_00000043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.2007
- Author(s)
  Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T
- Journal Title
  
  EMBO J 26(1)
  
  Pages: 113-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] The Nuclear Import of RNA helicase A is mediated by importin α32006
- Author(s)
  Satoko Aratani, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 340
  
  Pages: 125-133
- Data Source
  KAKENHI-PROJECT-17659304
[Patent] 小胞体ストレスシグナルを抑制することによる，薬剤の副作用としての体重増加や肥満を防止するために用いられる肥満防止剤2013
- Inventor(s)
  中島利博、荒谷聡子　他
- Industrial Property Rights Holder
  株式会社エム・エス・エス
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-121694
- Filing Date
  2013-06-10
- Data Source
  KAKENHI-PROJECT-24791006
[Patent] IL-2 産生抑制2013
- Inventor(s)
  中島利博, 荒谷聡子, 青野浩之, 西岡久寿樹
- Industrial Property Rights Holder
  参天製薬株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-060584
- Filing Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24791006
[Patent] 小胞体ストレスシグナルを抑制することによる, 薬剤の副作用としての体重増加や肥満を防止するために用いられる肥満防止剤2013
- Inventor(s)
  中島利博, 荒谷聡子, 臼井千恵, 山野嘉久, 西岡健弥, 藤田英俊, 八木下尚子, 伊藤健司, 中村郁朗, 西岡久寿樹
- Industrial Property Rights Holder
  株式会社エム・エス・エス
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-121694
- Filing Date
  2013-06-10
- Data Source
  KAKENHI-PROJECT-24791006
[Patent] 1,3,5-トリアジン誘導体を有する線維化予防又は治療剤2012
- Inventor(s)
  中島利博、瀬戸口靖弘、中島若巳、荒谷聡子、藤田英俊
- Industrial Property Rights Holder
  中島利博、瀬戸口靖弘、中島若巳、荒谷聡子、藤田英俊
- Industrial Property Rights Type
  特許
- Filing Date
  2012-12-26
- Data Source
  KAKENHI-PROJECT-24791006
[Patent] 1, 3, 5-トリアジン誘導体を有する線維化予防又は治療剤2012
- Inventor(s)
  中島利博, 瀬戸口靖弘, 中島若巳, 荒谷聡子, 藤田英俊
- Industrial Property Rights Holder
  学校法人東京医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-12-26
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] リウマチ滑膜細胞の新規増殖機構の解明2019
- Author(s)
  藤田　英俊、荒谷　聡子、横田　真穂、中島　利博
- Organizer
  第 6 回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] シノビオリンを介した全身性エリテマトーデスの病因・病態制御メカニズムの解析2019
- Author(s)
  荒谷　聡子、宮川　聡美、藤田　英俊、中島　利博
- Organizer
  第 6 回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] 線維筋痛症における当院での関節超音波検査の取り組み2018
- Author(s)
  西森　美佐子、中平　律子、山口　結花、梅原由加里、荒谷　聡子、中島　若巳、北川　中行、中谷　　孝、中島　利博
- Organizer
  日本線維筋痛症学会第 10 回学術集会
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] 脳内炎症に関わるキヌレニンの代謝機構の解明2018
- Author(s)
  藤田　英俊、石田　裕介、荒谷　聡子、横田　真穂、内野　博之、中島　利博
- Organizer
  日本線維筋痛症学会第 10 回学術集会
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] 脳内炎症に関わるキヌレニンの代謝機構の解明2018
- Author(s)
  藤田　英俊、石田　裕介、荒谷　聡子、横田　真穂、内野　博之、中島　利博
- Organizer
  日本線維筋痛症学会第 10 回学術集会
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] 線維筋痛症における当院での関節超音波検査の取り組み2018
- Author(s)
  西森　美佐子、中平　律子、山口　結花、梅原由加里、荒谷　聡子、中島　若巳、北川　中行、中谷　　孝、中島　利博
- Organizer
  日本線維筋痛症学会第 10 回学術集会
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] 線維筋痛症における関節超音波検査の活用法2017
- Author(s)
  西森美佐子、中平律子、山口結花、梅原由加里、荒谷聡子、中島若巳、北川中行、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会　第9回学術集会
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] モデルマウスを用いたヒトパピローマウイルスワクチン関連神経免疫異常症候群の病態解析2017
- Author(s)
  荒谷聡子、藤田英俊、黒岩義之、臼井千恵、横田俊平、中村郁郎、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会　第 9 回学術集会
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] Development of novel regulatory methods of mitochondrial functions2017
- Author(s)
  Fujita H, Aratani S, Yokota M and Nakajima T
- Organizer
  The 16th International Symposium on Advanced Technology (ISAT-16)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] モデルマウスを用いたヒトパピローマウイルスワクチン関連神経免疫異常症候群の病態解析2017
- Author(s)
  荒谷聡子、藤田英俊、黒岩義之、臼井千恵、横田俊平、中村郁郎、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会　第9回学術集会
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] Development of novel regulatory methods of mitochondrial functions2017
- Author(s)
  Fujita H, Aratani S, Yokota M, Nakajima T
- Organizer
  The 16th International Symposium on Advanced Technology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] A study on our novel murine model of Humanpapillomavirus-associated Neuroimmunopathic Syndrome (HANS)2017
- Author(s)
  Nakajima T, Aratani S, Fujita H, Kuroiwa Y, Usui C, Yokota S, Nakamura I, Nishioka K
- Organizer
  国際自律神経学会 ISAN2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] A study on our novel murine model of Humanpapillomavirus-associated Neuroimmunopathic Syndrome (HANS)2017
- Author(s)
  Nakajima T, Aratani S, Fujita H, Kuroiwa Y, Usui C, Yokota S, Nakamura I, Nishioka K
- Organizer
  国際自律神経学会 ISAN2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] 新規ヒトパピローマウイルスワクチン関連神経免疫異常症候群モデルマウスの樹立とその病態解析2017
- Author(s)
  荒谷聡子
- Organizer
  第18回運動器科学研究会
- Data Source
  KAKENHI-PROJECT-17K08671
[Presentation] 線維筋痛症における関節超音波検査の活用法2017
- Author(s)
  西森美佐子、中平律子、山口結花、梅原由加里、荒谷聡子、中島若巳、北川中行、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会　第 9 回学術集会
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] E3 ユビキチン化酵素シノビリオン阻害剤の臨床応用への可能性。2016
- Author(s)
  荒谷聡子、藤田英俊、西岡久寿樹、中島利博
- Organizer
  第 177 回東京医科大学医学会総会
- Place of Presentation
  (東京医科大学病院）東京都新宿区
- Year and Date
  2016-06-04
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] ヒトにおけるシノビオリン阻害剤の効果の検証。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  (KFCHall&Rooms)東京都墨田区
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] シノビオリン阻害剤の探索。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  KFC Hall & Rooms（東京　墨田区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] ヒトにおけるシノビオリン阻害剤の効果の検証。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  KFC Hall & Rooms（東京　墨田区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] リウマチ発症因子シノビオリンによる新規エネルギー代謝機構の解明。2016
- Author(s)
  藤田英俊、荒谷聡子、八木下尚子、山野嘉久、須藤カツ子、内野博之、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  アキバホール（東京　千代田区）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] 線維筋通症における当院の関節超音波検査の取り組みと役割2016
- Author(s)
  西森美佐子、山口結花、梅原由加里、澁谷美雪、荒谷聡子、中島若巳、北川中行、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会　第8回学術集会
- Place of Presentation
  KFC ホール、東京
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 関節リウマチにおける転写後修飾による多重化シグナル調節機構の解析。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子*、山野嘉久*、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  （アキバホール）東京都千代田区
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] 関節リウマチにおける転写後修飾による多重化シグナル調節機構の解析。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  アキバホール（東京　千代田区）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] ヒトにおけるシノビオリン阻害剤の効果の検証2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会　第8回学術集会
- Place of Presentation
  KFC ホール、東京
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] シノビオリン阻害剤の実用化に向けて。2016
- Author(s)
  荒谷聡子
- Organizer
  第 17 回運動器科学研究会
- Place of Presentation
  大阪大学中之島センター（大阪府　大阪市）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] Synoviolin, as a novel factor for understanding obesity and metabolic disorders based on chronic inflammation2016
- Author(s)
  Aratani S, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2016-07-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 関節リウマチにおける転写後修飾による多重化シグナル調節機構の解析2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  アキバプラザ、東京
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] シノビオリン阻害剤の実用化に向けて2016
- Author(s)
  荒谷聡子
- Organizer
  第17回運動器科学研究会
- Place of Presentation
  大阪大学中之島センター、大阪
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 線維筋痛症における超音波検査の役割2016
- Author(s)
  西森美佐子、山口結花、梅原由加里、中平律子、荒谷聡子、中島若巳、北川中行、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会　第8回学術集会
- Place of Presentation
  KFC ホール、東京
- Year and Date
  2016-09-18
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] マウスモデルを用いたシノビオリン阻害活性を有する天然物の効果の検証。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  KFC Hall & Rooms（東京　墨田区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] E3 Ubiquitin ligase synoviolin inhibitors has effects on obesity2016
- Author(s)
  Aratani S, Fujita H, Yagishita N*, Yokota M, Nishioka K, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases (ICOCD-2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] マウスモデルを用いたシノビオリン阻害活性を有する天然物の効果の検証。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  (KFC Hall&Rooms)東京都墨田区
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] シノビオリン阻害剤の探索。2016
- Author(s)
  藤田英俊、荒谷聡子、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 8 回学術集会
- Place of Presentation
  （KFC Hall&Rooms)東京都墨田区
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] シノビオリン阻害剤の実用化に向けて。2016
- Author(s)
  荒谷聡子
- Organizer
  第 17 回運動器科学研究会
- Place of Presentation
  （大阪大学中之島センター）大阪府大阪市
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] ヒトパピローマウイルスワクチン関連神経免疫異常症候群モデルマウスの解析2016
- Author(s)
  荒谷聡子、藤田英俊、黒岩義之、臼井千恵、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会　第8回学術集会
- Place of Presentation
  KFC ホール、東京
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] E3 Ubiquitin ligase synoviolin inhibitors has effects on obesity.2016
- Author(s)
  Aratani S, Fujita H, Yagishita N*, Yokota M, Nishioka K, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases(WCC 2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] シノビオリン阻害剤の実用化に向けて。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子*、中島若巳、西岡久寿樹、中島利博
- Organizer
  第 5 回医薬工 3 大学包括連携推進シンポジウム
- Place of Presentation
  (東京医科大学病院）東京都新宿区
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] Synoviolin, as a novel factor for understanding obesity and metabolic disorders based on chronic inflammation.2016
- Author(s)
  Aratani S, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases(WCC 2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] Synoviolin, as a novel factor for understanding obesity and metabolic disorders based on chronic inflammation2016
- Author(s)
  Aratani S, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases (ICOCD-2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] E3 Ubiquitin ligase synoviolin inhibitors has effects on obesity2016
- Author(s)
  Aratani S, Fujita H, Yagishita N, Yokota M, Nishioka K, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases
- Place of Presentation
  Las Vegas, USA
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] Synoviolin is a key regulator in chronic inflammation2016
- Author(s)
  藤田英俊、荒谷聡子、須藤カツ子、稲津正人、原直美、内野博之、西岡久寿樹、中島利博
- Organizer
  第 5 回医薬工 3 大学包括連携推進シンポジウム
- Place of Presentation
  (東京医科大学病院）東京都新宿区
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] リウマチ発症因子シノビオリンによる新規エネルギー代謝機構の解明。2016
- Author(s)
  藤田英俊、荒谷聡子、八木下尚子*、山野嘉久*、須藤カツ子*、内野博之、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  （アキバホール）東京都千代田区
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] 線維筋痛症の心的外傷性ストレスに対する脆弱性: 東日本大震災後 19 ヵ月間の追跡研究2015
- Author(s)
  臼井千恵、西岡健弥、荒谷聡子、藤田英俊、山野嘉久、中島利博、西岡久寿樹
- Organizer
  日本線維筋痛症学会第7回学術集会
- Place of Presentation
  ベルサール新宿
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 線維筋痛症における超音波検査の有用性の検討2015
- Author(s)
  西森美佐子、尾崎鈴子、藤島みどり、山口結花、梅原由加里、荒谷聡子、中島若巳、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会第7回学術集会
- Place of Presentation
  ベルサール新宿
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 大腿骨頸部骨折が発症の引き金となった背部痛・咽喉頭部異常感に仙骨硬膜外ブロックが有効であった線維筋痛症の 1 症例2015
- Author(s)
  中島若巳、荒谷聡子、藤田英俊、中谷孝、中島利博
- Organizer
  日本線維筋痛症学会第7回学術集会
- Place of Presentation
  ベルサール新宿
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 私達が開発した世界初の E3 ユビキチン化酵素シノビオリン阻害剤 LS シリーズの可能性について2015
- Author(s)
  荒谷聡子
- Organizer
  第16回運動器科学研究会
- Place of Presentation
  南日本新聞社みなみホール、鹿児島
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 小胞体ストレスと線維筋痛症における抗疼痛薬による肥満の関与について2014
- Author(s)
  荒谷聡子、山野嘉久、藤田英俊、八木下尚子、伊藤健司、長田賢一、中村郁朗、西岡久寿樹、中島利博
- Organizer
  第 58 回日本リウマチ学会　総会・学術集会
- Place of Presentation
  グランドプリンスホテル高輪
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] 抗疼痛薬による肥満と小胞体ストレスの関与2013
- Author(s)
  荒谷聡子、臼井千恵、山野嘉久、西岡健弥、藤田英俊、八木下尚子）、伊藤健司、長田賢一、中村郁朗、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 5 回学術集会
- Place of Presentation
  横浜開港記念館
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] リウマチと肥満を標的としたシノビオリン阻害剤の創薬開発研究の展開2013
- Author(s)
  荒谷聡子, 藤田英俊, 八木下尚子, 西岡久寿樹, 中島利博
- Organizer
  第3回医薬工3大学包括連携推進シンポジウム
- Place of Presentation
  東京薬科大学
- Year and Date
  2013-12-14
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] Synoviolin inhibitors have anti-obesity activity2013
- Author(s)
  Aratani S, Fujita H, Yagishita N, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics 2013
- Place of Presentation
  Four Seasons Hotel Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation]2013
- Author(s)
  荒谷聡子, 臼井千恵, 山野嘉久, 西岡健弥, 藤田英俊, 八木下尚子), 伊藤健司, 長田賢一, 中村郁朗, 西岡久寿樹, 中島利博
- Organizer
  日本線維筋痛症学会第5回学術集会
- Place of Presentation
  横浜 (横浜開港記念館)
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] Synoviolin inhibitors have anti-obesity activity2013
- Author(s)
  Aratani S, Fujita H, Yagishita N, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics 2013
- Place of Presentation
  Philadelphia, U.S.A
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] What tells us from Post-neonatal knock out of synoviolin2012
- Author(s)
  Nakajima T, Yagishita N, Aratani S, Fujita H, Nishioka K
- Organizer
  Ubiquitin Drug Discovery and Diagnostics 2012
- Place of Presentation
  Philadelphia, U.S.A
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] What tells us from Post-neonatal knock out of synoviolin2012
- Author(s)
  Nakajima T, Yagishita N, Aratani S, Fujita H, Nishioka K
- Organizer
  4th Annual Ubiquitin Drug Discovery & Diagnostics Conference 2012
- Place of Presentation
  Four Seasons Hotel Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] 線維筋痛症における疼痛シグナル解析モデルの構築2012
- Author(s)
  荒谷聡子, 臼井千恵, 八木下尚子, 西岡健弥, 山野嘉久, 藤田英俊, 伊藤健司, 長田賢一, 中村郁朗, 岡寛, 西岡久寿樹, 中島利博
- Organizer
  日本線維筋痛症学会第4回学術集会
- Place of Presentation
  長崎 (長崎ブリックホール)
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] Synoviolin ; a novel regulator for fibrosis2011
- Author(s)
  Aratani S Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics
- Place of Presentation
  Philadelphia, U. S. A.
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U. S. A.
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  八木下尚子、荒谷聡子, 他3名
- Organizer
  American College of Rheumatology the 75th Annual Scientific Meeting
- Place of Presentation
  Cicago
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] The functions of the post-translational modifications in rheumatoid arthritis2011
- Author(s)
  荒谷聡子, 他6名
- Organizer
  1st Bio-Rheumatology International Congress (BRIC)Tokyo,/The 8th GAEN Meeting
- Place of Presentation
  東京
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] 翻訳後タンパク質修飾からみた関節リウマチの病態研究2011
- Author(s)
  荒谷聡子, 他4名
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] The functions of the post-translational modifications in rheumatoid arthritis2011
- Author(s)
  Aratani S Yagishita N, Kanazawa T, Nakajima F, Yamano Y, Nishioka K, Nakajima T
- Organizer
  Bio-Rheumatology International Congress(BRIC) Tokyo : The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis2011
- Author(s)
  Aratani S Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics
- Place of Presentation
  Philadelphia, U. S. A.
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] E3 ubiquitin ligase Synoviolin is involved in liver fibrogenesis2011
- Author(s)
  Aratani S, Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  UbiquitinDrug Discovery andDiagnostics
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] ER stress signaling as a chronicity of imflammation2011
- Author(s)
  Yagishita N, Aratani S, Yamano Y, Nishioka K, Nakajima T
- Organizer
  2nd Tokyo-Shanghai Rheumatology Workshop
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] 翻訳後タンパク質修飾からみた関節リウマチの病態研究2011
- Author(s)
  荒谷聡子、八木下尚子、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場神戸国際展示場)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis2011
- Author(s)
  荒谷聡子, 他4名
- Organizer
  Ubiquitin Drug Discovery and Diagnostics 2011
- Place of Presentation
  Philadelphia
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-22790947
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U. S. A
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] Synoviolin ; a novel regulator for fibrosis2011
- Author(s)
  Aratani S, Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] 肝線維化における E3 ユビキチリンリガーゼシノビオリンの関与国際科学振興財団フォーラム分子消化器病学研究会2010
- Author(s)
  長谷川大輔、松本伸行、八木下尚子、荒谷聡子、山野嘉久、西岡久寿樹、中島利博、伊東文生
- Organizer
  第18回浜名湖シンポジウム
- Place of Presentation
  浜名湖
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] 東京医大メソッド2010
- Author(s)
  中島利博、荒谷聡子、西岡久寿樹
- Organizer
  第11回運動器研究会
- Place of Presentation
  万平ホテル軽井沢
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] GABA 構造類似薬の副作用による肥満と小胞体ストレスの関与について
- Author(s)
  荒谷聡子、臼井千恵、藤田英俊、八木下尚子、山野嘉久、西岡健弥、伊藤健司、長田賢一、中村郁朗、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第 6 回学術集会
- Place of Presentation
  ＪＡ長野
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26461476
[Presentation] The role of E3 ubiquitin ligase Synoviolin in bone destruction of rheumatoid arthritis.
- Author(s)
  Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T.
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京都（港区）〔グランドプリンスホテル新高輪〕
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] The functions of the post-translational modifications in rheumatoid arthritis
- Author(s)
  Aratani S, Yagishita N, Kanazawa T, Nakajima F, Yamano Y, Nishioka K, Nakajima T
- Organizer
  1st Bio-Rheumatology International Congress(BRIC) Tokyo/The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] リウマチと肥満を標的としたシノビオリン阻害剤の創薬開発研究の展開
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子、西岡久寿樹、中島利博
- Organizer
  第3 回医薬工 3 大学包括連携推進シンポジウム
- Place of Presentation
  東京薬科大学
- Data Source
  KAKENHI-PROJECT-24791006
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  1st Bio-Rheumatology International Congress(BRIC) Tokyo/The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-20249052

1. NAKAJIMA Toshihiro (90260752)

# of Collaborated Projects: 7 results

# of Collaborated Products: 74 results
2. YAGISHITA Naoko (40367389)

# of Collaborated Projects: 6 results

# of Collaborated Products: 31 results
3. YAMANO Yoshihisa (80445882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
4. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. OKADA Hidechika (30160683)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. AKATSU Hiroyasu (00399734)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 藤田英俊 (90571802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
8. HIGUCHI Ituro (80183573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KAWAHARA Koichi (10381170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KAMI Masahiro (50422423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. 中村裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ARATANI Satoko 荒谷 聡子

荒谷 聡子 アラタニ サトコ

Research Projects

Research Products

Co-Researchers

Improvement of vaccines against human papilloma viruses and evaluation of treatments of human papillomavirus vaccination-associated neuro-immunopathic syndrome with pathological model micePrincipal Investigator

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Involvement of Synoviolin in Muscle metabolism via two distinct pathways

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The regulation mechanisms of chronic pain via ER-stress pathway in fibromyalgiaPrincipal Investigator

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The study of bone destruction mechanism of rheumatoid arthritis by synoviolin

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Relationship of post-translational modifications in RA synoviocytesPrincipal Investigator

Principal Investigator

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The functions of the post-translational modifications in rheumatoid arthritisPrincipal Investigator

Principal Investigator

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二元的アポトーシス制御因子シノビオリンを標的としたがん研究

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シノビオリンの二方向性シグナル制御の生物学的意義

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Integrated study on implication of Synoviolin in multiprocesses of rheumatoid arthritis.

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滑膜細胞の小胞体機能亢進症 -関節リウマチの新しい病態モデルの提唱に向けた研究-

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[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis2017

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[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis Synoviolin is a novel pathogenic factor of arthropathy and chronic inflammation.2016

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[Journal Article] What occurs in human papilloma virus vaccination-associated neuro-immunopathic syndrome (HANS)? : implications of previous animal model studies2018

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[Journal Article] Identification of the inhibitory activity of E3 ligase Syvn1 in walnut extract.2018

ARATANI Satoko 荒谷聡子

荒谷聡子アラタニサトコ

[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis　Synoviolin is a novel pathogenic factor of arthropathy and chronic inflammation.2016