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SAKATA Toshiie  坂田 利家

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… Alternative Names

SAKATA Toshie  坂田 利家

SAKATA Oosiie  坂田 利家

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Researcher Number 50037420
External Links
Affiliation (based on the past Project Information) *help 2002 – 2005: NAKAMURA GAKUEN UNIVERSITY, PROFESSOR, 栄養科学研究部, 教授
2002 – 2004: 中村学園大学, 栄養科学部, 教授
1998 – 2001: 大分医科大学, 医学部, 教授
1998: 大分医科大学, 教授
1994 – 1996: 大分医科大学, 医学部, 教授 … More
1992: OITA MEDICAL UNIVERSITY, FACULTY OF MEDICINE PROFESSOR, 医学部, 教授
1991: 大分医科大学, 医学部, 助教授
1986 – 1990: 九州大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
内分泌・代謝学 / 環境生理学(含体力医学・栄養生理学) / Metabolomics
Except Principal Investigator
Metabolomics / Environmental physiology (including Physical medicine and Nutritional physiology) / 応用薬理学・医療系薬学 / 医学一般 / Metabolomics / 矯正・小児・社会系歯学 / Circulatory organs internal medicine / Orthodontic/Pediatric dentistry / General pharmacology
Keywords
Principal Investigator
神経ヒスタミン / 糖尿病 / 視床下部 / PC-1 / diabetes mellitus / レプチン / 肥満 / alpha-fluoromethylhistidine / 体温調節 / 摂食行動 … More / Histidine decarboxylase / Diabetes / Leptin / Neuronal histamine / Uncoupling protein / Energy homeostasis / uncoupling protein / agouti related protein / uncoupling protain / MC4-R / Yellow Ay mice / Zucker fatty rat / 高インスリン血症 / agouti related ptotain / 内臓脂肪 / 肥満糖尿病 / エネルギー代謝調節 / UCP / dbマウス / db / ヒスタミン受容体1ノックアウトマウス / ヒスタミン / 脱共役性蛋白 / genetic polymorphism / insulin resistance / Dominican Republic / common disease / obesity / 高脂質血症 / 遺伝子 / 高脂血症 / 疫学 / 遺伝子多型 / インスリン抵抗性 / ドミニカ共和国 / 生活習慣病 / fatty acids / insulin / central regulation of lipid metabolism / memory consolidation / leptin / hypothalamus / neuronal histamine / 学習 / グルコース作用 / グルコーストランスポーター / 脳機能障害 / 脂肪酸 / インスリン / 中枢性脂肪代謝調節 / 脳機能 / Energy metabolism / Genetic obesity / Thermoregulation / Adaptive behavior / Hypothalamic histamine / zucker obese rat / αーフルオロメチルヒスチジン / 概日リズム / ヒスタミン不応性 / Zuckerラット / 2ーdeoxyーDーglucoseによる遅発性摂食抑制 / 体温の恒常性維持 / 高温環境への適応行動 / 摂食の明暗周期消失 / αーfluoromethylhistidine / ヒスチジン脱炭酸酵素のmRNA発現量 / 視床下部神経ヒスタミン代謝回転 / 視床下部グリコーゲン / インターロイキン1-β / 三叉神経中脳路核 / α-flnoromethylhistidine / エネルギー代謝 / 適応行動 / ヒスチジン脱炭酸酵素 / Zucker遺伝性肥満ラット / CRF / 室旁核 / 視床下部腹内側核 / 視床下部外側野 / 2-deoxy-D-glucose / 交感神経 / 副腎 / 視床下部神経ヒスタミン / 2-DGの解離的調節性 / 2-デオキシ-D-グルコース(2-DG) / 視床下部性神経ペプチド / 褐色脂肪細胞組織 / 環境温 / 褐色脂肪組織 / カテコ-ラミン / 飲水行動 / α-フルオロメチルヒスチジン / 視床下部神経分泌性ヒスタミン / アミノ酸 / HPLC / ヒスチジン / 神経性食欲不振症 … More
Except Principal Investigator
視床下部 / 神経ヒスタミン / PC-1 / obesity / 肥満 / レプチン / インスリン抵抗性 / Zucker obese rat / 視床下部腹内側核 / insulin resistance / diabetes mellitus / Dominican Republic / SNP / 生活習慣病 / 多型 / 2型糖尿病 / ドミニカ共和国 / energy metabolism / エネルギー代謝 / neuronal histamine / diet-induced obesity / agouti mice / OLETF rat / fa rat / Zucker fa / 食餌誘導性肥満 / 肥満症 / 交感神経 / TNF-α / 糖尿病 / 液体飼料 / 低硬度飼料 / 食事性熱産生 / エネルギー代謝調節 / 咀嚼 / Neuronal Histamine / Feeding Behavior / Paraventricular Nucleus / Ventromedial Hypothalamus / Hypothalamus / Histamine H_1-receptor / ニューロン活動 / α-fluoromethylhistidine / H_1受容体 / 視索前野-前視床下野 / 視床下部背内側核 / 外側視床下野 / ヒスタミンH_1受容体拮抗薬 / αーfluoromethylhistidine / 神経性分泌ヒスタミン / 摂食行動 / 室傍核 / ヒスタミンH_1受容体 / 2,4,5-trihydroxypentanoic acid / 3,4-dihydroxybutanoic acid / Chemosensitive neuron / Ventromedial hypothalamic nucleus / Lateral hypothalamic area / Feeding behavior / Endogenous chemical substance / カルチトニン / グルカゴン / 3-DPA / 2-DTA / 内因性摂食調節物質 / 摂食行動調節 / 内在性有機酸 / 絶食 / 摂食抑制物質 / 糖・脂肪代謝 / 迷走神経 / 延髄背内側運動核 / 交感神経活動 / ブドウ糖感受性ニューロン / VMH / LHA / 内在性摂食抑制物質 / 孤束核 / 迷走神経背側運動核 / ラット / 摂食調節物質 / 化学感受性ニューロン / 視床下部外側野 / 内因性有機酸 / antiotensin II receptor blocker / Kir 6.2 / mitochondria / アンギオテンシンII受容体拮抗薬 / Kir6.2 / ミトコンドリア / adiponectin / brown adipose tissue / feeding behavior / leptin / hepatic-portal vein / 交換神経 / アディポネクチン / 褐色脂肪組織 / 食行動 / 肝門脈 / genetic analysis / 遺伝子多型 / 高脂血症 / 疫学 / 遺伝子解析 / sympathetic nervous system / taste / Diet-induced thermogenesis / mastication / 体脂肪 / 食事製熱産生 / 交感神経系 / 唾液タンパク質 / type 1 diabetes / differential display / pancreatic β cell / cDNA / NODマウス / スピードコンジェニック / HLA / 1型糖尿病 / MIN6 / Differential display / 膵β細胞 / マウス / fatty acid / hypothalamus / leptin resistance / Zucker fatty rat / 脂肪酸 / レプチン抵抗性 / Hypothalamic histamine / Histidine decarboxylase / TNF-alpha / Insulin resistence / Hyperinsulinemia / Diabetes mellitus / Hypertension / HPLC / 視床下部ヒスタミン / ヒスチジンデカリポキシラーゼ / 高インスリン血症 / 高血圧 / 気管支喘息 / 胃潰瘍 / 肥満細胞 / 中枢ヒスタミン神経系 / ヒスタミン代謝酵素 / ヒスタミン受容体 / ヒスタミン / causal effect / contingency table / Multivariate normal distribution / latent variable / developmental path model / causal analysis / cononical correlation / association model Less
  • Research Projects

    (18 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (38 People)
  •  食育における咀嚼の重要性をエネルギー代謝調節機構から解明し肥満予防に応用する研究

    • Principal Investigator
      中田 志保, FUJISE Takako
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Kyushu University
  •  GENOME-WIDE SEARCH FOR THE SUSCEPTIBILITY GENES FOR OBESE DIABETES IN THE DOMINICAN REPUBLIC

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA UNIVERSITY
      大分医科大学
  •  The role of mastication in the mechanism of regulation of energy metabolism

    • Principal Investigator
      FUJISE Takako, 中田 稔
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kyushu University
  •  ANALYSIS OF THE SUSCEPTIBILITY GENES FOR OBESE DIABETES IN THE DOMINICAN REPUBLICPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu, 坂田 利家
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Hepatic-portal leptin sensor regulates energy metabolism

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  STRUCTURE AND FUNCTION OF NOVEL GENE (BRG1) EXPRESSED IN PANCREATIC BETA CELLS

    • Principal Investigator
      HAMAGUCHI Kazuyuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERISTY
  •  『国際ヒスタミン・シンポジウム』の開催準備

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tohoku University
  •  INTERNATIONAL COMPARATIVE STUDY OF OBESE DIABETES - ANALYSIS OF ENVIRONMENTALAND GENETIC FACTORS -Principal Investigator

    • Principal Investigator
      SAKATA Toshiie
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Treatment of obesity and diabetes by the neuronal factorPrincipal Investigator

    • Principal Investigator
      SAKATA Toshiie
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  The involvement of fatty acids in the development of leptin resistance associated with obesity

    • Principal Investigator
      YOSIMATSU Hironobu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  社会や医学における現象モデルと実証に関する研究

    • Principal Investigator
      江島 伸興
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  Brain function disorder in diabetes mellitus and pathophysiological role of hypothalamic neuronal histaminePrincipal Investigator

    • Principal Investigator
      SAKATA Toshie
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  神経性食欲不振症の難治化する脳内ヒスタミン機能亢進とその治療法の開発Principal Investigator

    • Principal Investigator
      坂田 利家
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      大分医科大学
  •  Involvement of brain function in the development of hypertension and hyperinsulinemia

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Genetically obese animal : Defect in brain histamine control of adaptative functionPrincipal Investigator

    • Principal Investigator
      SAKATA Oosiie
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      OITA MEDICAL UNIVERSITY
      Kyushu University
  •  脂肪細胞のエネルギ-調節機能における神経性因子とその受容体機構の解析Principal Investigator

    • Principal Investigator
      坂田 利家
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Kyushu University
  •  Modulation of feeding behavior through brain histamine Hl-receptor

    • Principal Investigator
      KAZUMA Fujimoto
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Faculty of Medicine, Kyushu University
  •  Control of feeding behavior and processing of hierarchial humoral information through the central and peripheral chemosensitive systems.

    • Principal Investigator
      OKUKADO Nobuhisa, 大村 裕
    • Project Period (FY)
      1985 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      医学一般
    • Research Institution
      Kyushu University

All 2005 2004

All Journal Article

  • [Journal Article] Hypothalamic neuronal histamine modulates febrile response but not anorexia induced by lipopolysaccharide.2005

    • Author(s)
      Chiba S, Itateyama E, Oka K, Masaki T, Sakata T, Yoshimatsu H.
    • Journal Title

      Exp Biol Med. 230

      Pages: 334-342

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes.2004

    • Author(s)
      Hamaguchi K, Terao H, Kusuda Y, Yamashita T, Hazoury Bahles JA, Cruz LL M, Brugal V LI, Jongchong W B, Yoshimatsu H, Sakata T.
    • Journal Title

      J Clin Endocrinol Metab. 89

      Pages: 1359-1364

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] Genetic background of people in the Dominican Republic with or without obese type 2 diabetes revealed by mitochondrial DNA Polymorphism.2004

    • Author(s)
      Tajima A, Hamaguchi K, Terao H, Oribe A, Perrotta VM, Baez CA, Arias JR, Yoshimatsu H, Sakata T, Horai S.
    • Journal Title

      J Hum Genet 49

      Pages: 495-499

    • NAID

      10013600348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • 1.  YOSHIMATSU Hironobu (00166993)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 3 results
  • 2.  HAMAGUCHI Kazuyuki (60180931)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 3.  AONO Hirohi (80150936)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  FUJISE Takako (50284518)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  OOMURA Yutaka (30019517)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TERAO Hideo (10128192)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 7.  WATANABE Takehiko (70028356)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KAZUMA Fujimoto (50181392)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SATO Yasufumi (50178779)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SASAKI Yasunori (70332848)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OKEDA Toshimitsu (60136439)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  OKUKADO Nobuhisa (40037213)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  中田 志保 (80336081)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  KIMURA Akinori (60161551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOHNO Kimitoshi (00153479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OZAWA Hideki (90204198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  WAKANA Shigeharu (90192434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  INA Keisuke (20203193)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NINOMIYA Yuzo (50076048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  OCHIAI Satoru (20315097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAKUMA Tetsuya (80343359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  HARA Masahide (10244162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SAKAI Kiyoshi (90153840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SHIMIZU Nobuaki (50019634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  江島 伸興 (20203630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  内村 和宏 (30247283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  豊沢 英子 (40253801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  中野 重行 (10033341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  大内 和雄 (20006357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  白土 邦男 (80004761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  市川 厚 (10025695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  岡部 進 (90012624)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  大和谷 厚 (30116123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  黒川 衛 (70301380)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  中田 稔 (40014013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  片渕 俊彦 (80177401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  BELLO Merced
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  LUIS ivan br
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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