KOMATSU Norio 小松則夫

Researcher Number	50186798
Other IDs
External Links
Affiliation (Current)	2025: 順天堂大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 順天堂大学, 医学部, 特任教授 2009 – 2020: 順天堂大学, 医学部, 教授 2017: 順天堂大学, 医学部, 血液学講座 2008: 山梨大学, 大学院・医学工学統合研究部, 教授 2008: University of Yamanashi, 大学院・医学工学総合研究部, 教授 … More 2004 – 2007: 山梨大学, 医学部附属病院, 教授 2002 – 2003: 自治医科大学, 血液内科, 助教授 2000 – 2003: Jichi Medical School, Div Hematol, Associate professor, 医学部, 助教授 1992 – 1999: 自治医科大学, 医学部, 講師 1998: 自治医科大学, 講師 1986 – 1991: 自治医科大学, 医学部, 助手 1986: 自治医科大学, 医学部血液科, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Hematology / Biological Sciences / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Hematology / Kidney internal medicine / Basic Section 47040:Pharmacology-related … More / Pharmacology in pharmacy / Tumor therapeutics / Laboratory medicine / Biological Sciences Less
Keywords	Principal Investigator UT-7 / FKHRL1 / GATA-1 / 細胞周期 / APL / EPO / トロンボポエチン / apoptosis / FOXO3a / 薬剤耐性 … More / ATRA / エリスロポエチン / アポトーシス / 骨髄増殖性腫瘍 / transgenic mice / FOXO3A / TRAIL / siRNA / STI571 / 巨核球分化 / TPO / エリスロポエチン受容体 / 癌 / 本態性血小板血症 / 診断マーカー / all-trans retinoic acid / autocrine / drug-sensitivity / 巨核球 / DNAマイクロアレイ / トランスジェニックマウス / Stat3 / SIRT2 / Sirtuin / FTY720 / 急性前骨髄球性白血病 / 白血病 / imatinib / 慢性骨髄性白血病 / CML / 巨核球造血 / 赤血球造血 / WAF-1 / p21 / STAT蛋白 / 赤芽球分化 / 細胞内シグナル伝達 / シグナル伝達 / c-mpl / 転写因子 / 小胞体ストレス / 血小板 / 小胞体ストレス応答因子 / ゲノム / 細胞 / 遺伝子 / 急性白血病 / 骨髄線維症 / ドライバー遺伝子 / 家族性骨髄増殖性腫瘍 / 網羅的遺伝子解析 / ゲノム編集 / iPS / JAK2 / CRISPR/Cas9 / JAK2V617F変異 / iPS細胞 / 核酸 / 内科 / 疾患マーカー / 血小板増多 / 網羅的遺伝子発現解析 / 造血 / DNA microarray / cell cycle / megakaryopoiesis / GATA1 / 赤血球 / CD34 / Stat1 / DAF-16 / タモキシフェン / STAT 1 / STAT 3 / megakaryocytic differentiation / erythroid differentiation / erythropoietin / 顆粒球・マクロファージコロニー刺激因子 / チロシンキナーゼ / MAPキナーゼ / STAT1 / STAT3 / えりすろぽえちん / Phospholipase C-_<gamma>1 / Tyrosine phosphorylation / Signal transduction / Erythropoietin / PLC-γ1 / チロシンリン酸化 / leukemia / all trans retinoic acid / PP2A / sodium selenate / 活性酸素種 / ATRA耐性 / 全トランスレチノイン酸(ATRA) / 急性前骨髄球性白血病(APL) / プロテインホスファターゼ2A / 分化 / NAMPT / AML / Tenovin-6 / SIRT1 / IGF-1 / survivin / 多発性骨髄腫 / HIF-1 / protein phosphatase 2A / 分子標的治療 / オールトランスレチノイン酸 / 寿命関連遺伝子 / 抗癌薬 / 血液内科学 / HOXB4 / ホメオドメインタンパク質 / 細胞内局在 / Homothorax / MEIS1 / MAPK / HOXA9 / DAF16 / drag resistance / FHKRL1 / マイクロアレイ / dormancy / Forkhead転写因子 / RARβ / DR5 / CBP / GM / 顆粒球-マクロファージコロニー刺激因子 / STAT / 赤血球分化 / シグナル伝達分子 / c-jun / erythroleukemia / 赤白血病 … More Except Principal Investigator 骨髄増殖性腫瘍 / 造血幹細胞 / calreticulin / 造血因子 / 白血病 / 分子シャペロン / アポトーシス / apoptosis / JAK2 / HIF-1 / カルレティキュリン / トロンボポエチン / 原発性骨髄線維症 / thrombopoietin / erythropoietin / エリスロポエチン / 細胞増殖 / 受容体 / シグナル伝達 / サイトカイン / 変異型CALR / 本態性血小板血症 / Calreticulin / MPL / CALR / サイトカイン受容体 / マクロライド / ルキソリチニブ / オートファジー / myelofibrosis / macrolide / ruxolitinib / primary myelofibrosis / mitochondria / glucose / Bcl-xL / STAT3 / STAT5 / cAMP / hypertension / 血管平滑筋細胞 / 透析患者 / 培養血管平滑筋細胞 / hemopoietic stem cell disorders / erythropoietin receptor / megakaryocytic cell line / hemopoietic factor / hemopoietic stem cell / monoclonal antibody / hemopoietic stem cells / CD34 / 造血細胞コロニー / 染色体分析 / 遺伝子変異 / 活性酸素 / ミトコンドリア / 糖代謝 / 抗体 / 腫瘍マーカー / 巨核球 / 血小板 / 小胞体ストレス応答因子 / トロンボポエチン受容体 / triple-negative / 翻訳後修飾 / 骨髄繊維化 / ２量体 / 低分子化合物 / mutant CALR / JAK阻害薬 / UT7/TPO / proteasome inhibitor / ER stress / bortezomib / UT-7 / プロテアソーム阻害薬 / ERストレス / 疾患iPS細胞 / 免疫不全マウス / 奇形腫 / iPS細胞 / 骨髄線維症 / ドライバー変異 / 薬剤反応性 / スタチン / JAK2遺伝子変異 / ヒドロキシウレア / 個別化治療 / non-responder / アナグレリド / autophagy / thrombopietin / Death Receptor / MHC classs II / 抗体治療薬 / NKリンフォーマ / 悪性リンパ腫治療抗体 / humanized m Ab / Adult T cell Leukemia / lymphoma / cell death / therapy / Anapocosis / 成人T細胞白血病 / 悪性リンパ腫 / 細胞骨格 / 汎HLA- class II / 細胞死 / モノクローナル抗体 / 治療 / アナポコーシス / lymphocyte differerentiation / hemopoietic stromal cells / megakaryoblastic cell line / insertion of hemopoietic factor genes / hemopoietic factors / 単細胞培養 / 無血清培養 / インターリューキン6 / インターリューキン5 / MN血液型 / リンパ球の超源 / 造血支株細胞 / 巨核球性白血病株 / 造血因子遺伝子挿入 / 幹細胞の濃縮 / 染色体 / 発癌ウイルス / 巨核球産生 / インターリユキン5 / リンパ球の起源 / AAABC therapy / Bone marrow transplantation / Tumor spesific monoclonal antibodies / Tumor cell purging / T cell depletion / 自家骨髄移植法におけるAAABC療法 / イソプロテノールによる凍結解凍骨髄細胞の分化増殖の促進 / モノクローナル抗体による白血病細胞除 / FCMによる赤血球抗原の解析 / AAABC療法 / イソプロテノーによる造血幹細胞の分化増殖 / 造血幹細胞濃縮 / モノクローナル抗体による白血病細胞除去 / 白血病細胞表面抗原 / P13-kinase / hematopoietic stem cells / reactive oxygen species / Thrombopoietin / ポリフェノール / flavonoid / ROS / Hematopoietic stem cell / PI3キナーゼ / TRAIL / TPO / caspase / MAP kinase / MAPキナゼ / カスパーゼ / MAPキナーゼ / self-renewal / hematopoietic stem cell / STAT / 自己複製 / 体外増幅 / トロンボポイエチン / endothelial progenitor cells / MAPK system / vasular smooth muscle cell / signal transuduction / protein kinase A / MAPK / VEGF / 血管新生 / 心血管系合併症 / 血管内皮前駆細胞 / サイクリックAMP / マップキナーゼ系 / 血管平滑筋 / 高血圧 / 情報伝達 / vasoconstrictive substance / nitric oxide / intracellular calcium / vascular smooth muscle cell / hemodialysis / 一酸化窒素合成酵素 / IL-1β / 血管のリモデリング / 動脈硬化 / 一酸化窒素 / 血管收縮物質 / 血管収縮物質 / 細胞内Ca濃度 / transcription factor / erythropoietin gene / 赤白血病 / GATA-1 / STAT転写因子群 / 赤芽球分化 / 巨核球株細胞 / tyrosine phosphorylation / receptor / チロシンフォスファターゼ / アポトーシスと造血 / 幹細胞異常血液疾患 / エリスロポエチン受容体 / チロシン燐酸化 / 巨核球細胞株 / 造血因子受容体 / anti-leukemic cell antibody / spleen colony / mucopolysaccharide / c-kit / hemopoietic growth factors / 破骨細胞 / DIF / CD33 / WGA / cーkit / 抗白血病細胞抗体 / 脾コロニ- / ムコ多糖 / Cーkit / モノクロ-ナル抗体 / 組換ウイルス / キメラ遺伝子 / BCR/ABL融合点 / 病態モニタリング技術 / 病態モニタリング / BCR/ABLキメラ遺伝子 / 慢性骨髄性白血病 / 低酸素 / 骨髄増殖性疾患 / JAK2変異 / 低酸素環境 / SHP-2 / JAK2V617F / 家族性血小板機能異常症 / 発現調節 / 白血球 / 家族性血小板減少症 / RUNX1 / GLUT1 / 解糖 / PDK1 / グルコース / PDK-1 / Warbrug効果 / 細胞分化 / 転写因子 / キナーゼ Less

骨髄増殖性腫瘍における小胞体ストレス応答分子の細胞腫瘍性に及ぼす影響の解明
- Principal Investigator
  
  森下総司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
変異型CALRを標的とした骨髄増殖性腫瘍治療法の開発
- Principal Investigator
  
  荒木真理人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Elucidation of the mechanism of bone marrow fibrosis by focusing on the differences in tumorigenicity between mutant CALR types
- Principal Investigator
  
  今井美沙
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Elucidation of receptor maturation mechanism that causes myeloproliferative neoplasms
- Principal Investigator
  
  Masubuchi Nami
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Elucidate the autonomous activation mechanism of thrombopoietin receptor without genetic mutation
- Principal Investigator
  
  Yang Yinjie
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Understanding the mechanism of cell tumorigenesis promoted by essential thrombocythemia specific transcriptional networkPrincipal Investigator
- Principal Investigator
  
  Komatsu Norio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Establishment of therapeutic concept targeting homomultimerized mutant CALR
- Principal Investigator
  
  ARAKI MARITO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Novel ER stress-mediated therapy for tumor clones in myelofibrosis
- Principal Investigator
  
  Gotoh Akihiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tokyo Medical University
  Juntendo University
Development of novel therapeutic strategies for myeloproliferative neoplasms caused by mutant CALR
- Principal Investigator
  
  Yang Yinjie
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Juntendo University
Individualized pharmacotherapy for essential thrombocythemia using pharmacogenomic information
- Principal Investigator
  
  Takahashi Harumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Meiji Pharmaceutical University
Clarification of the pathogenesis of myeloproliferative neoplasms based on the identification of genetic factors in familial casesPrincipal Investigator
- Principal Investigator
  
  Komatsu Norio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Elucidation of molecular mechanism of cytokie receptor activation by mutant CALR
- Principal Investigator
  
  ARAKI MARITO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Establishment of in vitro model for essential thrombocythemia by mutant calreticulin
- Principal Investigator
  
  MIZUKAMI Yoshihisa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Establishment of therapeutic mAbs for malignant lymphoma
- Principal Investigator
  
  MATSUOKA Shuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Juntendo University
Selective elimination of tumor clones of primary myelofibrosis based on drug repositioning
- Principal Investigator
  
  Gotoh Akihiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Juntendo University
Identification of promising marker(s) for essential thrombocythemia diagnosis by differential gene expression approachPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Sirtuin阻害による急性前骨髄球性白血病細胞の分化誘導Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
A novel approach for monitoring the minimal residual disease in chronic myeloid leukemia
- Principal Investigator
  
  Sato Eriko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Juntendo University
ＡＴＲＡによるＡＰＬ細胞の分化誘導の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Development of the new treatment strategy of ATRA-resistant APL using PP2A-FOXO3A activation pathwayPrincipal Investigator
- Principal Investigator
  
  KOMATSU NORIO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Hypoxia attenuates growth of MPN cells through suppression of SHP-2 expression and subsequent inhibition of JAK2V617F activity
- Principal Investigator
  
  KIRITO Keita
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
Analysis of the mechanisms of RUNX1 gene regulation in the pathogenesis of leukemia
- Principal Investigator
  
  SAKOE Kumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
Role of glucose metabolism in hematological malignancy
- Principal Investigator
  
  KEITA Kirito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
Development of novel therapeutic strategy for targeting transcription factors expressed in cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
抗白血病薬によるTRAIL発現誘導と薬剤感受性Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
ホメオボックスHOXA9によるHOXB4の機能抑制と白血病発症Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
Thrombopoietin (TPO) regulates HIF-la levels through generation of mitochondrial reactive oxygen species
- Principal Investigator
  
  KIRITO Keita
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
FKHRL1による白血病細胞増殖抑制機構Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Yamanashi
白血病細胞のdormancy誘導におけるFKHRL1転写因子の役割Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
The development of targeted therapies using FKHRL1 for the treatment of leukemiaPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi
  Jichi Medical University
慢性骨随生白血病のSTI571耐性獲得におけるFKHRL1転写因子の役割Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Role of STAT5 in regulation of hematopoietic stem cell function
- Principal Investigator
  
  IWAMA Atsushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  THE UNIVERSITY OF TOKYO
Gene therapy for chronic granulomatous disease combined with in vivo expansion of transduced hematopoietic cells.
- Principal Investigator
  
  MORI Masaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
FKHRL1転写因子の機能解析と血液疾患モデルの樹立Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Invesigation on signal transduction of erythropoietin in vascular smooth muscle cells
- Principal Investigator
  
  KUSANO Eiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jichi Medical School
レチノイン酸による白血病細胞の赤血球分化決定機構の解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Establishment of model system for hematological disorders associated with mutated signal transduction moleculesPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
造血細胞のシグナル伝達
- Principal Investigator
  
  宮島篤
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Invesigation on cellular mechanism of erythropoietin induced hypertension
- Principal Investigator
  
  KUSANO Eiji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jichi Medical School
赤芽球分化と巨核球分化決定機構の解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
analysis of molecular mechanism of hematopoiesis and hematological disordersPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jich Medical School
赤芽球と巨核球分化の振り分け機構の解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
トロンボポエチン受容体と細胞内シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
エリスロポエチンシグナル伝達分子異常と造血障害の病態解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
トロンボポエチン細胞内シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Molecular control of the regulation of hemopoiesis and clinical application
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  jichi Medical School
エリスロポイエチン受容体遺伝子構造異常と造血障害Principal Investigator
- Principal Investigator
  
  小松則夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Characterization of 85Kd protein tyrosine phosphorylated by erythropoietin stimulationPrincipal Investigator
- Principal Investigator
  
  KOMATSU Norio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Analysis of collected primitive hemopoietic stem cells and its clinical application
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Isolation concentration, and preservation of hemopoietic stem cells and its clinical
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
造血幹細胞の分化と白血病はどのようにかかわりをもつか?
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Studies on multipotent stem cell clifferentiation using newly developed techniques an its clinical applications.
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL SCHOOL
T cell and tumor cell purging of marrow cell suspension using monoclonal antibodies - Effect of technique
- Principal Investigator
  
  AMEMIYA Youichi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School

[Book] 血液専門医テキスト改定第3版2019
- Author(s)
  小松則夫.
- Total Pages
  660
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] 未来型血液治療学2019
- Author(s)
  小松則夫.
- Total Pages
  254
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] WHO分類改定第4版による白血病・リンパ系腫瘍の病態学2019
- Author(s)
  木崎昌弘、田丸淳一、朝長万左男、小松則夫、吉岡智子，高橋直人，枝廣陽子，幣光太郎，下田和哉，水木満佐央，金倉譲，宮本敏浩，桐戸敬太，宮崎泰司，長谷川大輔，真部淳，南谷泰仁，麻生範雄，清井仁，佐々木伸也
- Total Pages
  527
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] WHO血液腫瘍分類　WHO分類2017をうまく活用するために2018
- Author(s)
  直江知樹、小松則夫、宮崎泰司、中村栄男、飯田真介、大島孝一、木下朝博、吉野正
- Total Pages
  463
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] 真性赤血球増加症専門家による　私の治療.2017
- Author(s)
  小松則夫.
- Total Pages
  2
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] これからの骨髄増殖性腫瘍の基礎研究と臨床のゴール.2017
- Author(s)
  小松則夫, 桐戸敬太, 荒木真理人
- Total Pages
  14
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] 骨髄線維症（MF）～分子病態の解明から新規治療薬の開発まで～序～骨髄線維症の現状と展望～2017
- Author(s)
  小松則夫.
- Total Pages
  5
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] 本態性血小板血症専門家による　私の治療.2017
- Author(s)
  小松則夫.
- Total Pages
  2
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] インターフェロンの復活.2017
- Author(s)
  小松則夫
- Total Pages
  8
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-17H04211
[Book] Annual Review血液、真性赤血球増加症の心血管イベントと治療強度20142014
- Author(s)
  小松則夫
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 骨髄増殖性腫瘍の病態と治療20142014
- Author(s)
  小松則夫
- Publisher
  日本内科学会雑誌
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 臨床血液2013
- Author(s)
  小松則夫
- Total Pages
  8
- Publisher
  日本血液学会
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 内科学第10版2013
- Author(s)
  小松則夫
- Total Pages
  12
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] 別冊:血液症候群IIIーその他の血液疾患を含めてー真性赤血球増加症20132013
- Author(s)
  小松則夫
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-23591407
[Book] カラーテキスト血液病学第2版2013
- Author(s)
  小松則夫
- Total Pages
  17
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591407
[Book] Annual Review血液2013
- Author(s)
  小松則夫
- Total Pages
  9
- Publisher
  中外医学社
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] カラーテキスト血液病学第2版2013
- Author(s)
  小松則夫
- Total Pages
  17
- Publisher
  中外医学社
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] 臨床血液2013
- Author(s)
  小松則夫
- Total Pages
  8
- Publisher
  日本血液学会
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] 日本臨床2013
- Author(s)
  小松則夫
- Total Pages
  8
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 内科学第10版赤血球増加症の原因と分類・相対的赤血球増加症・真性多血症・本態性血小板血症20132013
- Author(s)
  小松則夫
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 改訂第8版内科学書6　血液・造血器疾患2013
- Author(s)
  小松則夫
- Total Pages
  5
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] カラーテキスト血液病学第2版、骨髄増殖性腫瘍20132013
- Author(s)
  小松則夫
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 日本臨床2013
- Author(s)
  小松則夫
- Total Pages
  8
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] 改訂第8版内科学書6　血液・造血器疾患2013
- Author(s)
  小松則夫
- Total Pages
  5
- Publisher
  中山書店
- Data Source
  KAKENHI-PUBLICLY-25118725
[Book] ここまできた白血病/MDS治療本態性血小板血症20132013
- Author(s)
  小松則夫
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 内科学第10版2013
- Author(s)
  小松則夫
- Total Pages
  12
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] Annual Review血液2013
- Author(s)
  小松則夫
- Total Pages
  9
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 改訂第8版内科学書6血液・造血器疾患・神経疾患、本態性血小板血症・先天性家族性血小板血症・二次性(反応性)血小板増加症20132013
- Author(s)
  小松則夫
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 骨髄増殖性腫瘍、カラー版内科学20122012
- Author(s)
  小松則夫
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-23591407
[Book] 血液専門医テキスト2011
- Author(s)
  桐戸敬太・小松則夫
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591197
[Book] Mol Biol. (Culture of megakaryocytic cell lines : uses and limitations. Methods.)2004
- Author(s)
  Komatsu, N
- Total Pages
  13
- Data Source
  KAKENHI-PROJECT-16022255
[Book] Mol Biol.2004
- Author(s)
  Komatsu, N
- Total Pages
  13
- Publisher
  Culture of megakaryocytic cell lines : uses and limitations. Methods.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390306
[Book] Mol Biol.2004
- Author(s)
  Komatsu, N
- Total Pages
  13
- Data Source
  KAKENHI-PROJECT-15390306
[Journal Article] Establishment of isogenic induced pluripotent stem cells with or without pathogenic mutation for understanding the pathogenesis of myeloproliferative neoplasms2023
- Author(s)
  Liu Chang、Imai Misa、Edahiro Yoko、Mano Shuichi、Takei Hiraku、Nudejima Mai、Kurose Akira、Morishita Soji、Ando Miki、Tsuneda Satoshi、Araki Marito、Komatsu Norio
- Journal Title
  
  Experimental Hematology
  
  Volume: 118 Pages: 12-20
- DOI
  10.1016/j.exphem.2022.11.005
- Data Source
  KAKENHI-PROJECT-21K08376
[Journal Article] Non-driver gene mutation analysis in a large cohort of polycythemia vera and essential thrombocythemia2023
- Author(s)
  Morishita S, Hashimoto Y, Furuya C, Edahiro Y, Ochiai T, Shirane S, Inano T, Yasuda H, Ando M, Araki M, Komatsu N
- Journal Title
  
  European Journal of Haematology
  
  Volume: 110 Issue: 2 Pages: 131-136
- DOI
  10.1111/ejh.13882
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03715
[Journal Article] Reevaluation of cardiovascular risk factors for thrombotic events in 580 Japanese patients with essential thrombocythemia2023
- Author(s)
  Furuya C, Hashimoto Y, Morishita S, Inano T, Ochiai T, Shirane S, Edahiro Y, Araki M, Ando M, Komatsu N
- Journal Title
  
  Journal of Thrombosis and Thrombolysis
  
  Volume: 55 Pages: 263-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03715
[Journal Article] Phase 1 Clinical Trial of PPMX‐T003, a Novel Human Monoclonal Antibody Specific for Transferrin Receptor 1, to Evaluate Its Safety, Pharmacokinetics, and Pharmacodynamics2022
- Author(s)
  Ogama Yoichiro、Kumagai Yuji、Komatsu Norio、Araki Marito、Masubuchi Nami、Akiyoshi Hiroko、Matsuura Tadashi、Kirisako Hiromi、Kyoya Akiko、Nomura Fumiko、Ohira Yuta、Yokokawa Takuya、Yamamoto Yukiya
- Journal Title
  
  Clinical Pharmacology in Drug Development
  
  Volume: 0 Issue: 6 Pages: 1-9
- DOI
  10.1002/cpdd.1216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08405
[Journal Article] A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation2022
- Author(s)
  Watari Hiromi、Kageyama Hiromu、Masubuchi Nami、Nakajima Hiroya、Onodera Kako、Focia Pamela J.、Oshiro Takumi、Matsui Takashi、Kodera Yoshio、Ogawa Tomohisa、Yokoyama Takeshi、Hirayama Makoto、Hori Kanji、Freymann Douglas M.、Imai Misa、Komatsu Norio、Araki Marito、Tanaka Yoshikazu、Sakai Ryuichi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7262-7262
- DOI
  10.1038/s41467-022-34921-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06036, KAKENHI-PROJECT-21K08405, KAKENHI-PROJECT-21K18321, KAKENHI-PROJECT-21K19201, KAKENHI-PROJECT-22K20589, KAKENHI-PROJECT-19KK0178, KAKENHI-PUBLICLY-21H05712, KAKENHI-PROJECT-19H00918, KAKENHI-PROJECT-23K23695, KAKENHI-PROJECT-23K24176
[Journal Article] Clinical and biological relevance of CREB3L1 in Philadelphia chromosome-negative myeloproliferative neoplasms2022
- Author(s)
  De Marchi Federico、Okuda Maho、Morishita Soji、Imai Misa、Baba Terumi、Horino Mei、Mori Yosuke、Furuya Chiho、Ogata Satoko、Yang Yinjie、Ando Jun、Ando Miki、Araki Marito、Komatsu Norio
- Journal Title
  
  Leukemia Research
  
  Volume: 119 Pages: 106883-106883
- DOI
  10.1016/j.leukres.2022.106883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-21K16275, KAKENHI-PROJECT-20H03715
[Journal Article] Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors2022
- Author(s)
  Tanaka Yosuke....Goyama Susumu、Komatsu Norio、Takaku Tomoiku、Kitamura Toshio
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 271-271
- DOI
  10.1038/s41467-021-27928-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03685, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-22K19539, KAKENHI-PROJECT-20H00537
[Journal Article] Clinical features of acquired erythrocytosis: Low levels of serum erythropoietin in a subset of non‐neoplastic erythrocytosis patients2022
- Author(s)
  Mori Yosuke、Araki Marito、Morishita Soji、Imai Misa、Edahiro Yoko、Ito Masafumi、Ochiai Tomonori、Shirane Shuichi、Hashimoto Yoshinori、Yasuda Hajime、Ando Jun、Ando Miki、Komatsu Norio
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 2 Pages: 1079-1089
- DOI
  10.1002/cam4.4958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-20H03715
[Journal Article] MPNにおけるcalreticulin遺伝子変異の意義2021
- Author(s)
  増渕菜弥、荒木真理人、小松則夫
- Journal Title
  
  血液内科
  
  Volume: 82 Pages: 339-346
- Data Source
  KAKENHI-PROJECT-19K08848
[Journal Article] In silico-labeled ghost cytometry2021
- Author(s)
  Ugawa M、Kawamura Y、Toda K、Teranishi K、Morita H、Adachi Hiroaki、Tamoto Ryo、Nomaru Hiroko、Nakagawa Keiji、Sugimoto Keiki、Borisova Evgeniia、An Y、Konishi Y、Tabata S、Morishita S、Imai M、Takaku T、Araki M、Komatsu N、Hayashi Y、Sato I、Horisaki R、Noji H、Ota S
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.67660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08376
[Journal Article] MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations2021
- Author(s)
  Yasuda Shunichiro、Aoyama Satoru、Yoshimoto Ryoto、Li Huixin、Watanabe Daisuke、Akiyama Hiroki、Yamamoto Kouhei、Fujiwara Takeo、Najima Yuho、Doki Noriko、Sakaida Emiko、Edahiro Yoko、Imai Misa、Araki Marito、Komatsu Norio、Miura Osamu、Kawamata Norihiko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 4 Pages: 424-440
- DOI
  10.1007/s12185-021-03180-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871
[Journal Article] Clinical characteristics, prognostic factors, and outcomes of patients with essential thrombocythemia in Japan: the JSH-MPN-R18 study2021
- Author(s)
  Hashimoto Y, Ito T, Gotoh A, Nakamae M, Kimura F, Koike M, Kirito K, Wada H, Usuki K, Tanaka T, Mori T, Wakita S, Saito TI, Kada A, Saito AM, Shimoda K, Sugimoto Y, Kurokawa T, Tomita A, Edahiro Y, Akashi K, Matsumura I, Takenaka K, Komatsu N
- Journal Title
  
  International Journal of Hematology
  
  Volume: 115 Issue: 2 Pages: 208-221
- DOI
  10.1007/s12185-021-03253-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-20H03713, KAKENHI-PROJECT-21H02949, KAKENHI-PROJECT-21K08407
[Journal Article] Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety2021
- Author(s)
  Watari Hiromi、Kageyama Hiromu、Masubuchi Nami、Nakajima Hiroya、Onodera Kako、Focia Pamela J.、Oshiro Takumi、Matsui Takashi、Kodera Yoshio、Ogawa Tomohisa、Yokoyama Takeshi、Hirayama Makoto、Hori Kanji、Freymann Douglas M.、Komatsu Norio、Araki Marito、Tanaka Yoshikazu、Sakai Ryuichi
- Journal Title
  
  bioRixiv
  
  Volume: -
- DOI
  10.1101/2021.10.29.466502
- Open Access
- Data Source
  KAKENHI-PROJECT-21K08405, KAKENHI-PROJECT-20J11377
[Journal Article] Diagnosis of essential thrombocythemia2021
- Author(s)
  OCHIAI Tomonori、MORISHITA Soji、KOMATSU Norio
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 32 Issue: 4 Pages: 370-375
- DOI
  10.2491/jjsth.32.370
- NAID
  130008080837
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-20H03715
[Journal Article] Clinical impacts of the mutational spectrum in Japanese patients with primary myelofibrosis2021
- Author(s)
  Morishita Soji、Ochiai Tomonori、Misawa Kyohei、Osaga Satoshi、Inano Tadaaki、Fukuda Yasutaka、Edahiro Yoko、Ohsaka Akimichi、Araki Marito、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 4 Pages: 500-507
- DOI
  10.1007/s12185-020-03054-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871
[Journal Article] Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia2021
- Author(s)
  Inano Tadaaki、Araki Marito、Morishita Soji、Imai Misa、Kihara Yoshihiko、Okuda Maho、Yang Yinjie、Ito Masafumi、Osaga Satoshi、Mano Hiroyuki、Edahiro Yoko、Ochiai Tomonori、Misawa Kyohei、Fukuda Yasutaka、Ando Jun、Komatsu Norio
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 17702-17702
- DOI
  10.1038/s41598-021-97106-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-21K16250, KAKENHI-PROJECT-21K16275
[Journal Article] CREB3L1 overexpression as a potential diagnostic marker of Philadelphia chromosome?negative myeloproliferative neoplasms2020
- Author(s)
  Morishita Soji、Yasuda Hajime、Yamawaki Saya、Kawaji Hideya、Itoh Masayoshi、Edahiro Yoko、Imai Misa、Kogo Yasushi、Tsuneda Satoshi、Ohsaka Akimichi、Hayashizaki Yoshihide、Ito Masafumi、Araki Marito、Komatsu Norio
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 884-892
- DOI
  10.1111/cas.14763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-20H03715, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848
[Journal Article] Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin2020
- Author(s)
  Edahiro Yoko、Araki Marito、Komatsu Norio
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 8 Pages: 2682-2688
- DOI
  10.1111/cas.14503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848
[Journal Article] Interferon therapy for pregnant patients with essential thrombocythemia in Japan2020
- Author(s)
  Edahiro Yoko、Yasuda Hajime、Gotoh Akihiko、Morishita Soji、Suzuki Toshifumi、Takeda Jun、Ando Jun、Tsutsui Miyuki、Itakura Atsuo、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 1 Pages: 106-111
- DOI
  10.1007/s12185-020-03001-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-18K08372
[Journal Article] JAK2 exon 12 mutation in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis: Not an exclusive mutation to polycythaemia vera2019
- Author(s)
  Inano, T. Araki, M. Morishita, S. Imai, M. Yasuda, H. Nitta, H. Ito, M. Edahiro, Y. Ochiai, T. Misawa, K. Fukuda, Y. Ohsaka, A. Komatsu, N.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 187 Issue: 1
- DOI
  10.1111/bjh.16146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17K16195
[Journal Article] Clinical and molecular features of patients with prefibrotic primary myelofibrosis previously diagnosed as having essential thrombocythemia in Japan2019
- Author(s)
  Edahiro Yoko、Araki Marito、Inano Tadaaki、Ito Masafumi、Morishita Soji、Misawa Kyohei、Fukuda Yasutaka、Imai Misa、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  European Journal of Haematology
  
  Volume: 00 Issue: 6 Pages: 1-5
- DOI
  10.1111/ejh.13236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19203, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871
[Journal Article] Mutant calreticulin interacts with MPL in the secretion pathway for activation on the cell surface2019
- Author(s)
  Masubuchi Nami、Araki Marito、Yang Yinjie、Hayashi Erina、Imai Misa、Edahiro Yoko、Hironaka Yumi、Mizukami Yoshihisa、Kihara Yoshihiko、Takei Hiraku、Nudejima Mai、Koike Masato、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 2 Pages: 499-509
- DOI
  10.1038/s41375-019-0564-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-18K16098, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16126
[Journal Article] Evidence for prevention of renal dysfunction associated with primary myelofibrosis by cytoreductive therapy2019
- Author(s)
  Fukuda Yasutaka、Araki Marito、Yamamoto Kouji、Morishita Soji、Inano Tadaaki、Misawa Kyohei、Ochiai Tomonori、Edahiro Yoko、Imai Misa、Yasuda Hajime、Gotoh Akihiko、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  Haematologica
  
  Volume: 印刷中 Issue: 11 Pages: e506-e509
- DOI
  10.3324/haematol.2018.208876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-17K16195
[Journal Article] The role of calreticulin mutations in myeloproliferative neoplasms2019
- Author(s)
  Araki Marito、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 111 Issue: 2 Pages: 200-205
- DOI
  10.1007/s12185-019-02800-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-17H04211
[Journal Article] Efficacy and safety of ruxolitinib in patients with myelofibrosis: a single-center retrospective analysis2019
- Author(s)
  枝廣陽子、小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 7 Pages: 755-760
- DOI
  10.11406/rinketsu.60.755
- NAID
  130007688020
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871
[Journal Article] MPNのゲノム解析研究の進歩2019
- Author(s)
  奥田真帆、荒木真理人、小松則夫
- Journal Title
  
  血液内科
  
  Volume: 79 Pages: 556-564
- Data Source
  KAKENHI-PROJECT-19K08848
[Journal Article] 骨髄増殖性腫瘍の遺伝子異常2019
- Author(s)
  荒木真理人、森下総司、小松則夫
- Journal Title
  
  臨床検査
  
  Volume: 63 Pages: 790-796
- Data Source
  KAKENHI-PROJECT-19K08848
[Journal Article] Vitamin B6 deficiency is prevalent in primary and secondary myelofibrosis patients2019
- Author(s)
  Yasuda Hajime、Tsutsui Miyuki、Ando Jun、Inano Tadaaki、Noguchi Masaaki、Yahata Yuriko、Tanaka Masaru、Tsukune Yutaka、Masuda Azuchi、Shirane Shuichi、Misawa Kyohei、Gotoh Akihiko、Sato Eriko、Aritaka Nanae、Sekiguchi Yasunobu、Sugimoto Keiji、Komatsu Norio
- Journal Title
  
  International Journal of Hematology
  
  Volume: 110 Issue: 5 Pages: 543-549
- DOI
  10.1007/s12185-019-02717-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-18K07273
[Journal Article] Meet the MPN experts in EHA　フィラデルフィア染色体陰性MPNの診断・治療の課題と将来展望 MPNを巡る臨床的課題と将来展望を語る(座談会)2018
- Author(s)
  小松則夫(順天堂大学血液内科学), Kiladjian Jean-Jacques, ROY Lydia, Shih Lee-Yung, Chen Chin-Cheng, 後藤明彦
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Pages: 263-267
- Data Source
  KAKENHI-PROJECT-18K06690
[Journal Article] Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations2018
- Author(s)
  Hiraku Takei, Yoko Edahiro, Shuichi Mano, Nami Masubuchi, Yoshihsa Mizukami, Misa Imai, Soji Morishita, Kyohei Misawa, Tomonori Ochiai, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 6 Pages: 791-802
- DOI
  10.1111/bjh.15266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J11017, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16126, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-18H04164
[Journal Article] round-table talk Meet the MPN experts in EHA フィラデルフィア染色体陰性MPNの診断･治療の課題と将来展望2018
- Author(s)
  小松則夫, Kiladjan JJ, Roy L, Shih L-Y, Chen C-C, 後藤明彦
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Issue: 2 Pages: 256-267
- DOI
  10.20837/5201802256
- ISSN
  1344-6940
- Year and Date
  2018-01-30
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Effect of ruxolitinib therapy on the quality-of-life of Japanese patients with myelofibrosis.2018
- Author(s)
  Oritani K, Ohishi K, Okamoto S, Kirito K, Komatsu N, Tauchi T, Handa H, Saito S, Takenaka K, Shimoda K, Okada H, Amagasaki T, Wakase S, Shimozuma K, Akashi K.
- Journal Title
  
  Curr Med Res Opin.
  
  Volume: 34 Pages: 531-537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04211
[Journal Article] Homomultimerization of mutant calreticulin is a prerequisite for MPL binding and activation2018
- Author(s)
  Araki Marito、Yang Yinjie、Imai Misa、Mizukami Yoshihisa、Kihara Yoshihiko、Sunami Yoshitaka、Masubuchi Nami、Edahiro Yoko、Hironaka Yumi、Osaga Satoshi、Ohsaka Akimichi、Komatsu Norio
- Journal Title
  
  Leukemia
  
  Volume: 33 Issue: 1 Pages: 122-131
- DOI
  10.1038/s41375-018-0181-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16098, KAKENHI-PROJECT-18K16100, KAKENHI-PROJECT-18K16126, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859
[Journal Article] Evaluation of the dose and efficacy of ruxolitinib in Japanese patients with myelofibrosis.2018
- Author(s)
  Kirito K, Okamoto S, Ohishi K, Tauchi T, Handa H, Saito S, Takenaka K, Shimoda K, Oritani K, Akashi K, Okada H, Amagasaki T, Suzuki K, Yonezu T, Komatsu N
- Journal Title
  
  Int J Hematol
  
  Volume: 107(1) Issue: 1 Pages: 92-97
- DOI
  10.1007/s12185-017-2332-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09872, KAKENHI-PROJECT-17H04210, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K09470
[Journal Article] The 2014 BCSH criteria and the 2016 WHO criteria for essential thrombocythemia: A comparison in a large-scale cohort.2018
- Author(s)
  Ochiai T, Yasuda H, Araki M, Misawa K, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  Eur J Haematol
  
  Volume: 印刷中 Issue: 6 Pages: 544-549
- DOI
  10.1111/ejh.13041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559, KAKENHI-PROJECT-18K06690
[Journal Article] Skewed megakaryopoiesis in human iPS cell-derived hematopoietic progenitor cells harboring calreticulin mutations2018
- Author(s)
  Hiraku Takei, Yoko Edahiro, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Misa Imai, Soji Morishita, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19587
[Journal Article] Transfusion independence achieved with pomalidomide therapy in a patient with primary myelofibrosis2018
- Author(s)
  枝廣陽子, 後藤明彦, 稲野資明, 筒井深雪, 築根豊, 安田肇, 小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 3 Pages: 323-325
- DOI
  10.11406/rinketsu.59.323
- NAID
  130006627427
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-15K07972
[Journal Article] Mutational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms.2018
- Author(s)
  Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  Int J Hematol
  
  Volume: 印刷中 Issue: 6 Pages: 673-680
- DOI
  10.1007/s12185-018-2421-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17H04211
[Journal Article] Meet the MPN experts in EHA　フィラデルフィア染色体陰性MPNの診断・治療の課題と将来展望 MPNを巡る臨床的課題と将来展望を語る(座談会)2018
- Author(s)
  小松則夫, Kiladjian Jean-Jacques, ROY Lydia, Shih Lee-Yung, Chen Chin-Cheng, 後藤明彦
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Pages: 263-267
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Mutant molecular chaperone activates cytokine receptor as a homomultimer2018
- Author(s)
  Araki Marito、Komatsu Norio
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 81 Pages: 35201-35202
- DOI
  10.18632/oncotarget.26221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859
[Journal Article] Multiple Placental Infarcts in a Pregnant Woman with Essential Thrombocythemia.2018
- Author(s)
  Edahiro Y, Ando J, Suzuki T, Fukumura Y, Masuda A, Sakayori S, Takeda J, Maruyama Y, Makino S, Itakura A, Komatsu N.
- Journal Title
  
  Internal Medicine.
  
  Volume: 57 Pages: 3647-3650
- NAID
  130007531198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04211
[Journal Article] Effect of ruxolitinib therapy on the quality of life of Japanese patients with myelofibrosis.2018
- Author(s)
  Oritani K, Ohishi K, Okamoto S, Kirito K, Komatsu N, Tauchi T, Handa H, Saito S, Takenaka K, Shimoda K, Okada H, Amagasaki T, Wakase S, Shimozuma K, Akashi K
- Journal Title
  
  Curr Med Res Opin
  
  Volume: 34 Issue: 3 Pages: 531-537
- DOI
  10.1080/03007995.2017.1415874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08894, KAKENHI-PROJECT-16K09872, KAKENHI-PROJECT-15K09470, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17H04210, KAKENHI-PROJECT-15K07972
[Journal Article] Multiple Placental Infarcts in a Pregnant Woman with Essential Thrombocythemia2018
- Author(s)
  Edahiro Yoko、Ando Jun、Suzuki Toshifumi、Fukumura Yuki、Masuda Azuchi、Sakayori Shiori、Takeda Jun、Maruyama Yojiro、Makino Shintaro、Itakura Atsuo、Komatsu Norio
- Journal Title
  
  Internal Medicine
  
  Volume: 57 Issue: 24 Pages: 3647-3650
- DOI
  10.2169/internalmedicine.1311-18
- NAID
  130007531198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-18K07273, KAKENHI-PROJECT-15K07972
[Journal Article] The impact of myeloproliferative neoplasms (MPNs) on patient quality of life and productivity: results from the international MPN Landmark survey.2017
- Author(s)
  Harrison CN, Koschmieder S, Foltz L, Guglielmelli P, Flindt T, Koehler M, Mathias J, Komatsu N, Boothroyd RN, Spierer A, Perez Ronco J, Taylor-Stokes G, Waller J, Mesa RA.
- Journal Title
  
  Ann Hematol.
  
  Volume: 96 Issue: 10 Pages: 1653-1665
- DOI
  10.1007/s00277-017-3082-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04211
[Journal Article] Hmga2 collaborates with JAK2 V617F in the development of myeloproliferative neoplasms2017
- Author(s)
  Ueda K, Ikeda K, Ikezoe T, Harada-Shirado K, Ogawa K, Hashimoto Y, Sano T, Ohkawara H, Kimura S, Shichishima-Nakamura A, Nakamura Y, Shikama Y, Mori T, Mason PJ, Bessler M, Morishita S, Komatsu N, Shide K, Shimoda K, Koide S, Aoyama K, Oshima M, Iwama Aand Takeishi Y.
- Journal Title
  
  Blood Advances
  
  Volume: 1 Issue: 15 Pages: 1001-1015
- DOI
  10.1182/bloodadvances.2017004457
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09852, KAKENHI-PROJECT-17H04210, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K09457, KAKENHI-PROJECT-15K09483, KAKENHI-PROJECT-15K09484, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K19582, KAKENHI-PROJECT-17K19687
[Journal Article] Somatic mutations of calreticulin in myeloproliferative neoplasms2017
- Author(s)
  Imai Misa、Araki Marito、Komatsu Norio
- Journal Title
  
  Int J Hematol
  
  Volume: 105 Issue: 6 Pages: 743-747
- DOI
  10.1007/s12185-017-2246-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-17H04211
[Journal Article] The 2016 WHO diagnostic criteria for polycythemia vera renders an accurate diagnosis to a broader range of patients including masked polycythemia vera: Comparison with the 2008 WHO diagnostic criteria.2017
- Author(s)
  Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
- Journal Title
  
  Am J Hematol
  
  Volume: 92 Issue: 7
- DOI
  10.1002/ajh.24752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559
[Journal Article] Assessing the safety and efficacy of ruxolitinib in a multicenter, open-label study in Japanese patients with myelofibrosis.2017
- Author(s)
  Komatsu N, Kirito K, Shimoda K, Ishikawa T, Ohishi K, Ohyashiki K, Takahashi N, Okada H, Amagasaki T, Yonezu T, Akashi K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 105 Pages: 309-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04211
[Journal Article] Novel molecular mechanism of cellular transformation by a mutant molecular chaperone in myeloproliferative neoplasms2017
- Author(s)
  Araki Marito、Komatsu Norio
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 10 Pages: 1907-1912
- DOI
  10.1111/cas.13327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211
[Journal Article] Assessing the safety and efficacy of ruxolitinib in a multicenter, open-label study in Japanese patients with myelofibrosis.2017
- Author(s)
  Komatsu N, Kirito K, Shimoda K, Ishikawa T, Ohishi K, Ohyashiki K, Takahashi N, Okada H, Amagasaki T, Yonezu T, Akashi K.
- Journal Title
  
  Int J Hematol
  
  Volume: 105 Issue: 3 Pages: 309-317
- DOI
  10.1007/s12185-016-2130-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms.2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N
- Journal Title
  
  Blood
  
  Volume: 127 Issue: 10 Pages: 1307-16
- DOI
  10.1182/blood-2015-09-671172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-15K19559, KAKENHI-PROJECT-26893264
[Journal Article] 骨髄増殖性腫瘍を引き起こす変異型calreticulinによるTPO受容体の活性化.2016
- Author(s)
  今井美沙, 荒木真理人, 森下総司, 小松則夫.
- Journal Title
  
  血液内科
  
  Volume: 73 Pages: 789-793
- Data Source
  KAKENHI-PROJECT-16K09859
[Journal Article] 骨髄増殖性腫瘍の遺伝子変異　最近の知見.2016
- Author(s)
  荒木真理人, 森下総司, 小松則夫.
- Journal Title
  
  臨床血液.
  
  Volume: 57 Pages: 2526-2534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09859
[Journal Article] 2.Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation.2016
- Author(s)
  Matsuoka S, Ishii Y, Nakao A, Abe M, Ohtsuji N, Momose S, Jin H, Arase H, Sugimoto K, Nakauchi Y, Masutani H, Maeda M, Yagita H, Komatsu N, Hino O.
- Journal Title
  
  PLoS One.
  
  Volume: 11(3)
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06880
[Journal Article] Gene mutations in myeloproliferative neoplasms2016
- Author(s)
  荒木真理, 森下総司, 小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 57 Issue: 12 Pages: 2526-2534
- DOI
  10.11406/rinketsu.57.2526
- NAID
  130005286786
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] 診断における遺伝子変異の意義と問題点2016
- Author(s)
  小松則夫
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 17 Pages: 347-353
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] 骨髄増殖性腫瘍をひき起こす変異型calreticulinによるTPO受容体の活性化機構2016
- Author(s)
  今井美沙, 荒木真理人, 森下総司, 小松則夫
- Journal Title
  
  血液内科
  
  Volume: 73 Pages: 789-793
- NAID
  40021031814
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines.2016
- Author(s)
  Miyahara K, Kazama H, Kokuba H, Komatsu S, Hirota A, Takemura J, Hirasawa K,Moriya S, Abe A, Hiramoto M, Ishikawa T, Miyazawa K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49 Issue: 5 Pages: 1848-1858
- DOI
  10.3892/ijo.2016.3673
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460478, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K19187, KAKENHI-PROJECT-16K21387
[Journal Article] Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation.2016
- Author(s)
  Matsuoka S, Ishii Y, Nakao A, Abe M, Ohtsuji N, Momose S, Jin H, Arase H, Sugimoto K, Nakauchi Y, Masutani H, Maeda M, Yagita H, Komatsu N, Hino O.
- Journal Title
  
  PLoS One.
  
  Volume: 11(3)
- NAID
  120005838168
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06880
[Journal Article] Current problems in the diagnosis of Philadelphia-negative myeloproliferative neoplasms in Japan2015
- Author(s)
  白根脩一、荒木真理人、森下総司、枝廣陽子、大阪顯通、小松則夫
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 7 Pages: 877-882
- DOI
  10.11406/rinketsu.56.877
- NAID
  130005093120
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-15K19559
[Journal Article] Melting curve analysis after T allele enrichment (MelcaTle) as a highly sensitive and reliable method for detecting the JAK2V617F mutation.2015
- Author(s)
  Morishita S, Takahashi K, Araki M, Hironaka Y, Sunami Y, Edahiro Y, Tsutsui M, Ohsaka A, Tsuneda S, Komatsu N.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0122003-e0122003
- DOI
  10.1371/journal.pone.0122003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
[Journal Article] Reactivation of hepatitis B virus during treatment with hydroxyurea in an elderly patient with essential thrombocythemia.2015
- Author(s)
  Watanabe N, Yasuda H, Aota Y, Ando J, Aoyama T, Tanaka M, Gotoh A, Komatsu N.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 15 Issue: 6 Pages: 812-3
- DOI
  10.1111/ggi.12461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Usefulness of BCSH Criteria for Diagnosing Japanese Polycythemia Vera -Comparative Analysis with WHO 2008 Criteria-2015
- Author(s)
  Yahata Y, Gotoh A, Komatsu N
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 61 Pages: 287-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972
[Journal Article] Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells.2015
- Author(s)
  Moriya S, Komatsu S, Yamasaki K, Kawai Y, Kokuba H, Hirota A, Che XF, Inazu M, Gotoh A, Hiramoto M, Miyazawa K
- Journal Title
  
  Int J Oncol.
  
  Volume: Feb;46(2) Issue: 2 Pages: 474-86
- DOI
  10.3892/ijo.2014.2773
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860398, KAKENHI-PROJECT-26430170, KAKENHI-PROJECT-26460478, KAKENHI-PROJECT-26670589, KAKENHI-PROJECT-15K07972
[Journal Article] Consequences of the JAK2V617F allele burden for the prediction of transformation into myelofibrosis from polycythemia vera and essential thrombocythemia.2015
- Author(s)
  Shirane S, Araki M, Morishita S, Edahiro Y, Sunami Y, Hironaka Y, Noguchi M, Koike M, Sato E, Ohsaka A, Komatsu N.
- Journal Title
  
  Int J Hematol
  
  Volume: 101 Issue: 2 Pages: 148-53
- DOI
  10.1007/s12185-014-1721-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-26893264
[Journal Article] JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan2014
- Author(s)
  EdahiroY, Morishita S, Takahashi K, Hironaka Y, Yahata Y, Sunami Y, Shirane S, Tsutsui M, Noguchi M, Koike M, Imai K, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Araki M, Komatsu N
- Journal Title
  
  Int J Hematol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan2014
- Author(s)
  EdahiroY, Morishita S, Takahashi K, Hironaka Y, Yahata Y, Sunami Y, Shirane S, Tsutsui M, Noguchi M, Koike M, Imai K, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Araki M, Komatsu N.
- Journal Title
  
  Int J Hematol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118725
[Journal Article] JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan2014
- Author(s)
  EdahiroY, Morishita S, Takahashi K, Hironaka Y, Yahata Y, Sunami Y, Shirane S, Tsutsui M, Noguchi M, Koike M, Imai K, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Araki M, Komatsu N
- Journal Title
  
  Int J Hematol
  
  Volume: 99(5) Issue: 5 Pages: 625-634
- DOI
  10.1007/s12185-014-1567-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
[Journal Article] A Monoclonal Expansion of Epstein-Barr Virus-Infected Natural Killer Cells after Allogeneic Peripheral Blood Stem Cell Transplantation2013
- Author(s)
  Isobe Y, Hamano Y, Ito Y, Kimura H, Tsukada N, Sugimoto K, Komatsu N
- Journal Title
  
  J Clin Virol.
  
  Volume: 56 Pages: 150-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] Inhibition of the Nad-Dependent Protein Deacetylase Sirt2 Induces Granulocytic Differentiation in Human Leukemia Cells2013
- Author(s)
  Sunami Y, Araki M, Hironaka Y, Morishita S, Kobayashi M, E. L. Liew, Edahiro Y, Tsutsui M, Ohsaka A, Komatsu N
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 2 Pages: e57633-e57633
- DOI
  10.1371/journal.pone.0057633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-23800055, KAKENHI-PUBLICLY-25118725, KAKENHI-PUBLICLY-23118528
[Journal Article] MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.2013
- Author(s)
  Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.
- Journal Title
  
  J Exp Med.
  
  Volume: 210 Issue: 12 Pages: 2661-2673
- DOI
  10.1084/jem.20130112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460492
[Journal Article] Rituximab Activates Syk and Akt in Cd20-Positive B Cell Lymphoma Cells Dependent on Cell Membrane Cholesterol Levels2013
- Author(s)
  Nozaki Y, Mitsumori T, Yamamoto T, Kawashima I , Shobu Y, Hamanaka S, Nakajima K, Komatsu N, Kirito K
- Journal Title
  
  Exp Hematol
  
  Volume: 41 Issue: 8 Pages: 687-696
- DOI
  10.1016/j.exphem.2013.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725
[Journal Article] A monoclonal expansion of Epstein-Barr virus-infected natural killer cells after allogeneic peripheral blood stem cell transplantation2013
- Author(s)
  Isobe Y, Hamano Y, Ito Y, Kimura H, Tsukada N, Sugimoto K, Komatsu N
- Journal Title
  
  J Clin Virol
  
  Volume: 56(2) Issue: 2 Pages: 150-152
- DOI
  10.1016/j.jcv.2012.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725
[Journal Article] Computational dissection of distinct microRNA activity signatures associated with peripheral T cell lymphoma subtypes2013
- Author(s)
  Suzuki HI
- Journal Title
  
  Leukemia
  
  Volume: 27 Issue: 10 Pages: 2107-2111
- DOI
  10.1038/leu.2013.121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-24689018, KAKENHI-PUBLICLY-25118725
[Journal Article] An induced pluripotent stem cell-mediated and integration-free factor VIII expression system.2013
- Author(s)
  Yakura y, et. al.
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 431 Issue: 2 Pages: 336-341
- DOI
  10.1016/j.bbrc.2012.12.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00264, KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-23659040, KAKENHI-PROJECT-24659469, KAKENHI-PROJECT-24790974
[Journal Article] Expression of Epstein-Barr Virus-Encoded Proteins in Extranodal NK/T-cell Lymphoma, Nasal Type (ENKL): Differences in Biologic and Clinical Behaviors of LMP1-Positive and -Negative ENKL.2012
- Author(s)
  Kanemitsu N,
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18（8） Issue: 8 Pages: 2164-2172
- DOI
  10.1158/1078-0432.ccr-11-2395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590338, KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-23591407
[Journal Article] T/NK cell type chronic active Epstein-Barr virus disease in adults : an underlying condition for Epstein-Barr virus-associated T/NK-cell lymphoma2012
- Author(s)
  Isobe Y, Aritaka N, Setoguchi Y, Ito Y, Kimura H, Hamano Y, Sugimoto K, Komatsu N
- Journal Title
  
  J Clin Pathol
  
  Volume: 65(3) Issue: 3 Pages: 278-282
- DOI
  10.1136/jclinpath-2011-200523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-23591564, KAKENHI-PROJECT-24659493
[Journal Article] Usefulness of systemic computed tomography (CT) scanning in the detection of malignant lymphadenopathy.2011
- Author(s)
  Ichikawa K, Sugimoto K, Isobe Y, Kuwatsuru R, Sasaki M, Horiguchi I, Komatsu N.
- Journal Title
  
  Medicine (Baltimore).
  
  Volume: 90 Pages: 396-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] Alternately binding probe competitive PCR as a simple, cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms.2011
- Author(s)
  Morishita S, Komatsu N, Kirito K, Koda AH, Sekiguchi Y, Tsuneda S, Noda N.
- Journal Title
  
  Leuk Res.
  
  Volume: 35 Pages: 1632-1636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-1 7 producing immunophenotype to anaplastic large cell lymphoma2011
- Author(s)
  Matsuyama H, Suzuki HI, Nishimori H, Noguchi M, Yao T, Komatsu N, et al
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 6881-6892
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23118528
[Journal Article] APOA-1 is a Novel Marker of Erythroid Cell Maturation from Hematopoietic Stem Cells in Mice and Humans.2011
- Author(s)
  Inoue T, Sugiyama D, Kurita R, Oikawa T, Kulkeaw K, Kawano H, Miura Y, Okada M, Suehiro Y, Takahashi A, Marumoto T, Inoue H, Komatsu N, Tani K
- Journal Title
  
  Humans. Stem Cell Rev.
  
  Volume: 7 Pages: 43-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] Alternately binding probe competitive PCR as a simple, cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms2011
- Author(s)
  Morishita S, Komatsu N, Kirito K, Koda AH, Sekiguchi Y, Tsuneda S, Noda N
- Journal Title
  
  Leuk Res.
  
  Volume: 35 Pages: 1632-1636
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23118528
[Journal Article] Alternately binding probe competitive PCR as a simple2011
- Author(s)
  Morishita S, Komatsu N, Kirito K, Koda AH, Sekiguchi Y, Tsuneda S, Noda N
- Journal Title
  
  cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms Leukemia Research
  
  Volume: 35 Pages: 1632-1636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591197
[Journal Article] miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma.2011
- Author(s)
  Matsuyama H, Suzuki HI, Nishimori H, Noguchi M, Yao T, Komatsu N, Mano H, Sugimoto K, Miyazono K
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 6881-6892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] Identification of Bcl-2/IgH fusion sequences using real-time PCR and chip-based microcapillary electrophoresis.2011
- Author(s)
  Tabe Y, Kawase Y, Miyake K, Satoh N, Aritaka N, Isobe Y, Oshimi K, Komatsu N, Miida T, Ohsaka A
- Journal Title
  
  Clin Chem Lab Med.
  
  Volume: 49 Pages: 809-815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Journal Article] NF-κB mediates aberrantactivation of HIF-1 in malignantlymphoma2010
- Author(s)
  Qiao Q, Nozaki Y, Sakoe K, Komatsu N, Kirito K
- Journal Title
  
  Exp Hematol
  
  Volume: 38(12) Pages: 1199-1208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591197
[Journal Article] FOXO3A as a key molecule forall-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia2010
- Author(s)
  Sakoe Y, Sakoe K, Kirito K, Ozawa K, Komatsu N
- Journal Title
  
  Blood
  
  Volume: 115(18) Pages: 3787-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591197
[Journal Article] FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia2010
- Author(s)
  Sakoe Y, Sakoe K, Kirito K, Ozawa K, Komatsu N.
- Journal Title
  
  Blood 115
  
  Pages: 3787-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] NF-κB mediates aberrant activation of HIF-1 in malignant lymphoma2010
- Author(s)
  Qiao Q, Nozaki Y, Sakoe K, Komatsu N, Kirito K.
- Journal Title
  
  Exp Hematol 38
  
  Pages: 1199-1208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] Familial sideroblastic anemia associated with cardiac atrial septal defect.2009
- Author(s)
  Mori M, Nakamoto S, Akifuji Y, Tanaka T, Komatsu N, Hatake K, Ozawa K.
- Journal Title
  
  Am J Hematol 7
  
  Pages: 451-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] HIF-1 prevents the overproduction of mitochondrial ROS after cytokine stimulation through induction of PDK-12009
- Author(s)
  Kirito K, Hu Y, Komatsu N.
- Journal Title
  
  Cell cycle 8
  
  Pages: 2844-2849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myelomacells to melphalan2009
- Author(s)
  Hu Y, Kirito K, Yoshida K, MitsumoriT, Nakajima K, Nozaki Y, Hamanaka S, Nagashima T, Kunitama M, Sakoe K, Komatsu N
- Journal Title
  
  Molecular cancer therapeutics
  
  Volume: 8 Pages: 2329-2338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591197
[Journal Article] Inhibition of HIF-1 function enhances the sensitivity of multiple myeloma cells to melphalan2009
- Author(s)
  ongzhen Hu, Kirito K, Yoshida K, Mitsumori T, Nakajima K, Nozaki Y, Hamanaka S, Nagashima T, Kunitama M, Sakoe K, Komatsu N.
- Journal Title
  
  Molecular cancer therapeutics 8
  
  Pages: 2329-2338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] HIF-1prevents the overproduction of mitochondrial ROS after cytokine stimulation through induction of PDK-12009
- Author(s)
  Kirito K, Hu Y, Komatsu N
- Journal Title
  
  Cell cycle
  
  Volume: 8 Pages: 2844-2849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591197
[Journal Article] A novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies.2008
- Author(s)
  Kirito K, Sakoe K, Shinoda D, Takiyama Y, Kaushansky K, Komatsu N
- Journal Title
  
  Haematologica 93
  
  Pages: 155-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] Throrabopoietin (TPO) regulates HIF-lalpha levels through generation of mitochondrial reactive oxvgen species2008
- Author(s)
  Yoshida, K., Kirito, K., Yongzhen, H., Ozawa, K., Kaushansky, K., Komatsu, N.
- Journal Title
  
  Int J Hematol 88
  
  Pages: 43-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf22008
- Author(s)
  Nagai T, Kikuchi S, Ohmine K, Miyoshi T, Nakamura M, Kondo T, Furuyama K, Komatsu N, Ozawa K.
- Journal Title
  
  J Cell Biochem 104(2)
  
  Pages: 680-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] A novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies2008
- Author(s)
  Kirito K, Sakoe K, Shinoda D, Takiyama Y, Kaushansky K, Komatsu N
- Journal Title
  
  Haematologica 93
  
  Pages: 155-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] Regulation of erythropoiesis and pathogenesis of anemia.2008
- Author(s)
  Komatsu N
- Journal Title
  
  Nippon Rinsho 66
  
  Pages: 420-422
- NAID
  40015862583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species2008
- Author(s)
  Yoshida K, Kirito K, Yongzhen H, Ozawa K, Kaushansky K, Komatsu N
- Journal Title
  
  International journal of hematology 88
  
  Pages: 43-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] Thrombopoietin (TPO) regulates HIF-1a levels through generation of mitochondrial reactive oxygen species2008
- Author(s)
  Yoshida K, Kirito K, Yongzhen H,Ozawa K, Kaushansky K, Komatsu N.
- Journal Title
  
  Int J Hematol 88(1)
  
  Pages: 43-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Thrombopoietin (TPO) regulates HIF-1a levels through generation of mitochondrial reactive oxygen species.2008
- Author(s)
  Yoshida K, Kirito K, Yongzhen H, Ozawa K, Kaushansky K, Komatsu N.
- Journal Title
  
  Int J Hematol 88
  
  Pages: 43-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591114
[Journal Article] Identification of erythropoietin-induced microRNAs in hematopoietic cells during erythroid differentiation2008
- Author(s)
  Kosaka N, Sugiura K,Yamamoto Y, Yoshioka Y, Miyazaki H, Komatsu N, Ochiya T, Kato T.
- Journal Title
  
  Br J Haematol 142
  
  Pages: 293-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] .A novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies2008
- Author(s)
  K. Kirito, K. Sakoe, D. Shinoda, Y. Takiyama, K. Kaushansky and N. Komatsu
- Journal Title
  
  Haematologica 93
  
  Pages: 155-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies2008
- Author(s)
  Kirito K, Sakoe K, Shinoda D, Takiyama Y, Kaushansky K, Komatsu N.
- Journal Title
  
  Haematologica 93
  
  Pages: 155-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Regulation of erythropoiesis and pathogenesis of anemia2008
- Author(s)
  Komatsu N.
- Journal Title
  
  Nippon Rinsho 66
  
  Pages: 420-422
- NAID
  40015862583
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand2007
- Author(s)
  Kikuchi S, Nagai T, Kunitama M, Kirito K, Ozawa K, Komatsu N.
- Journal Title
  
  Cancer science 98
  
  Pages: 1949-58
- NAID
  10019996600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] Activation of FKHRL1 plays an important role in protecting erythroid cells from erythropoietin deprivation-induced apoptosis in a human erythropoietin-dependent leukemia cell line2007
- Author(s)
  Uchida M, Kirito K, Endo H, Ozawa K, Komatsu N.
- Journal Title
  
  UT-7/EPO. Int J Hematol 86(4)
  
  Pages: 315-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] .Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand2007
- Author(s)
  S. Kikuchi, T. Nagai, M. Kunitama, K. Kirito, K. Ozawa and N. Komatsu
- Journal Title
  
  Cancer Science 98
  
  Pages: 1949-1958
- NAID
  10019996600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosisinducing ligand2007
- Author(s)
  Kikuchi S, Nagai T, Kunitama M, Kirito K, Ozawa K, Komatsu N.
- Journal Title
  
  Cancer Sci 98(12)
  
  Pages: 1949-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Cloning and characterization of a human BCR/ABL-positive cell line2007
- Author(s)
  Miyoshi T, Nagai T, Kikuchi S, Ohmine K, Nakamura M, Hanafusa T, Komatsu N, Ozawa K.
- Journal Title
  
  K562/RR, resistant to the farnesyltransferase inhibition by tipifarnib. Exp Hematol 35(9)
  
  Pages: 1358-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Erythropoietin for the treatment of chemotherapy-induced anemia2007
- Author(s)
  Komatsu N
- Journal Title
  
  Rinsho Ketsueki 48
  
  Pages: 1435-1441
- NAID
  10019829495
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Erythropoietin for the treatment of chemotherapy-induced anemia2007
- Author(s)
  Komatsu N.
- Journal Title
  
  Rinsho Ketsueki 48(10)
  
  Pages: 1435-41
- NAID
  10019829495
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Activation of FKHRL1 plays an important role in protecting erythroid cells from erythropoietin deprivation-induced apoptosis in a human erythropoietin-dependent leukemia cell line, UT-7/EPO2007
- Author(s)
  Uchida M, Kirito K, Endo H, Ozawa K, Komatsu N
- Journal Title
  
  International journal of hematology 86
  
  Pages: 315-24
- NAID
  10019990096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591103
[Journal Article] RUNX1 suppression induces megakaryocytic differentiation of UT-7/GM cells2006
- Author(s)
  Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Okada Y, Doi T.
- Journal Title
  
  Biochem Biophys Res Commun. 345・1
  
  Pages: 78-84
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Suppression of RUNX1 by siRNA in megakaryocytic UT-7/GM cells2006
- Author(s)
  Y.Okada, R.Nagai, E.Matsuura, Y.Hoshika, E.Nakata, H.Nagura, A.Watanabe, N.Komatsu, T.Doi.
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf) 50
  
  Pages: 261-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] RUNX1 suppression induces megakaryocytic differentiation of UT-7/GM cells2006
- Author(s)
  R.Nagai, E.Matsuura, Y.Hoshika, E.Nakata, H.Nagura, A.Watanabe, N.Komatsu, Y.Okada, T.Doi.
- Journal Title
  
  Biochem Biophys Res Commun 345-1
  
  Pages: 78-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] RUNX1 suppression induces megakaryocytic differentiation of UT- 7/GM cells2006
- Author(s)
  Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Okada Y, Doi T.
- Journal Title
  
  Biochem Biophys Res Commun 345
  
  Pages: 78-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Suppression of RUNX1 by siRNA in megakaryocytic UT-7/GM cells2006
- Author(s)
  Okada Y, Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Doi T.
- Journal Title
  
  Nucleic Acids Symposium Series 50
  
  Pages: 261-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390282
[Journal Article] Suppression of RUNX1 by siRNA in megakaryocytic UT-7/GM cells.2006
- Author(s)
  Okada Y, Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Doi T
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf) 50
  
  Pages: 261-262
- Data Source
  KAKENHI-PROJECT-17659291
[Journal Article] RUNX1 suppression induces megakaryocytic differentiation of UT-7/GM cells2006
- Author(s)
  Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Okada Y, Doi T
- Journal Title
  
  Biochem Biophys Res Commun. 345・1
  
  Pages: 78-84
- Data Source
  KAKENHI-PROJECT-17659291
[Journal Article] Suppression of RUNX1 by siRNA in megakaryocytic UT-7/GM cells.2006
- Author(s)
  Okada Y, Nagai R, Matsuura E, Hoshika Y, Nakata E, Nagura H, Watanabe A, Komatsu N, Doi T.
- Journal Title
  
  Nucleic Acids Symp Ser (Oxf) 50
  
  Pages: 261-262
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Relative importance of apoptosis and cell cycle blockage in the synergistic effect of combined R115777 and imatinib treatment in BCR/ABL-positive cell lines2005
- Author(s)
  T.Miyoshi, T Nagai, K.Ohmine, M.Nakamura, Y.Kano, K.Muroi, N.Komatsu, K Ozawa
- Journal Title
  
  Biochem Pharmacol 69-11
  
  Pages: 1585-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] lron deficiency anemia with marked thrombocytosis complicated by central retinal vein occlusion2005
- Author(s)
  T.Nagai, N.Komatsu, Y.Sakata, Y.Miura, K.Ozawa.
- Journal Title
  
  Intern Med 44-10
  
  Pages: 1090-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Autologous gamete cryopreservation before hemopoietic stem cell transplantation2005
- Author(s)
  T.Nagashima, K.Muroi, C.Kawano-Yamamoto, T.Miyoshi, K.Ohmine, M.Toshima, A.Miyazato, M.Takatoku, T.Nagai, M.Mori, N.Komatsu, K.Ozawa.
- Journal Title
  
  Med Sci Monit 11-3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT-7/GM2005
- Author(s)
  W.Takahashi, K.Sasaki, N.Komatsu, K.Mitani.
- Journal Title
  
  Cancer Sci 96-340-348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Retropharyngeal abscess due to methicillin-resistant Staphylococcus aureus in a case of acute myeloid leukemia2005
- Author(s)
  K.Sato, T.Izumi, M.Toshima, T.Nagai, K.Muroi, N.Komatsu, K.Ozawa
- Journal Title
  
  Intern Med 44-4
  
  Pages: 346-9
- NAID
  10015461976
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Thrombopoietin initiates demethylation-based transcription of GP6 during megakaryocyte differentiation2005
- Author(s)
  S.Kanaji, T.Kanaji, B.Jacquelin, M.Chang, D.J.Nugent, N.Komatsu, M.Moroi, K.Izuhara, T.J.Kunicki.
- Journal Title
  
  Blood 105-10
  
  Pages: 3888-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Inhibition by Rho-kinase and protein kinase C of myosin phosphatase is involved in thrombin-induced shape change of megakaryocytic leukemia cell line UT-7/TPO2005
- Author(s)
  A.Yazaki, S.Tamaru, Y.Sasaki, N.Komatsu, H.wada, H.Shiku, M.Nishikawa.
- Journal Title
  
  Cell Signal 17-3
  
  Pages: 321-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha2005
- Author(s)
  K.Kirito, N.Fox, N.Komatsu, K.Kaushansky.
- Journal Title
  
  Blood 105-11
  
  Pages: 4258-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  T.Toki, F.Katsuoka, R.Kanezaki, G.Xu, H.Kurotaki, J.Sun, T.Kamio, S.Watanabe, S.Tandai, K.Terui, S.Yagihashi, N.Komatsu, K.Igarashi, M.Yamamoto, E.Ito.
- Journal Title
  
  Blood 105-8
  
  Pages: 3100-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591005
[Journal Article] Hypoxia inhibits JAK2V617F activation via suppression of SHP-2 function in MPN cells
- Author(s)
  Mitumori T, Nozaki Y, Yamamoto T, Kawashima I, Shobu Y, Nakajima K, Komatsu N, Kirito K
- Journal Title
  
  Exp Hematol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407
[Patent] 切断型の変異型Ｃａｌｒｅｔｉｃｕｌｉｎに結合する抗体、及び骨髄増殖性腫瘍の診断、予防又は治療薬2020
- Inventor(s)
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Holder
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K08848
[Patent] 非公開2020
- Inventor(s)
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Holder
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K08848
[Patent] 多血症治療薬2020
- Inventor(s)
  張黎臨、野村富美子、荒木真理人、小松則夫
- Industrial Property Rights Holder
  張黎臨、野村富美子、荒木真理人、小松則夫
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19K08848
[Patent] 抗切断型変異ＣＡＬＲ－ＣＤ３二重特異性抗体及び医薬組成物2020
- Inventor(s)
  小松則夫、荒木真理人、木原慶彦、石田陽治、ほか
- Industrial Property Rights Holder
  小松則夫、荒木真理人、木原慶彦、石田陽治、ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-143551
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K08848
[Patent] 非公開2019
- Inventor(s)
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Holder
  荒木真理人、小松則夫、木原慶彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-036119
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16K09859
[Patent] 骨髄増殖性腫瘍の診断2018
- Inventor(s)
  森下総司, 小松則夫, 他
- Industrial Property Rights Holder
  森下総司, 小松則夫, 他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-078074
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04211
[Patent] 骨髄増殖性腫瘍の診断2018
- Inventor(s)
  森下総司，小松則夫，山脇紗耶，常田聡，川路英哉，伊藤昌可
- Industrial Property Rights Holder
  森下総司，小松則夫，山脇紗耶，常田聡，川路英哉，伊藤昌可
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-078074
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15K15368
[Patent] リンパ節腫脹病変の評価方法2014
- Inventor(s)
  森下総司、荒木真理人、小松則夫
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-003192
- Acquisition Date
  2014-01-10
- Overseas
- Data Source
  KAKENHI-PROJECT-23591407
[Patent] 急性白血病における分化誘導薬の診断薬2013
- Inventor(s)
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-212611
- Acquisition Date
  2013-10-10
- Overseas
- Data Source
  KAKENHI-PROJECT-23591407
[Patent] 急性白血病における分化誘導薬の診断薬2013
- Inventor(s)
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Holder
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-212611
- Filing Date
  2013-10-10
- Data Source
  KAKENHI-PUBLICLY-25118725
[Patent] JAK2変異遺伝子の検出方法2013
- Inventor(s)
  森下総司,小松則夫
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-207818
- Acquisition Date
  2013-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-23591407
[Patent] 急性前骨髄球性白血病治療薬のスクリーニング方法2012
- Inventor(s)
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-181369
- Filing Date
  2012-08-20
- Overseas
- Data Source
  KAKENHI-PROJECT-23591407
[Patent] 急性前骨髄性白血病治療薬のスクリーニング方法2012
- Inventor(s)
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Holder
  荒木真理人、小松則夫、角南義孝
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-181369
- Filing Date
  2012-08-20
- Data Source
  KAKENHI-PUBLICLY-23118528
[Patent] JAK2遺伝子の変異解析法2010
- Inventor(s)
  野田尚宏,関口勇地,森下総司,常田聡,小松則夫,蓮沼彩,桐戸敬太
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所・早稲田大学・順天堂大学
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2012-034580
- Acquisition Date
  2010-08-03
- Overseas
- Data Source
  KAKENHI-PROJECT-23591407
[Presentation] Elucidation of the molecular mechanism for the cleavage of mutant calreticulin.2022
- Author(s)
  Shumpei Yoshikawa, Marito Araki, Yoshihiko Kihara, Nami Masubuchi, Yinjie Yang, Soji Morishita, Misa Imai, Yoko Edahiro, Miki Ando, Norio Komatsu.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08424
[Presentation] The MPL mutation is a risk factor for thrombosis in addition to JAK2V617F mutation in ET patients2022
- Author(s)
  Chiho Furuya, Yoshinori Hashimoto, Soji Morishita, Miki Ando, Norio Komatsu
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Elucidation of the molecular mechanism for the cleavage of mutant calreticulin.2022
- Author(s)
  Shumpei Yoshikawa, Marito Araki, Yoshihiko Kihara, Nami Masubuchi, Yinjie Yang, Soji Morishita, Misa Imai, Yoko Edahiro, Miki Ando, Norio Komatsu.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08405
[Presentation] Hypertriglyceridemia is a strong risk factor for thrombosis in ET patients2022
- Author(s)
  Chiho Furuya, Yoshinori Hashimoto, Soji Morishita, Miki Ando, Norio Komatsu
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Elucidation of the molecular mechanism for the cleavage of mutant calreticulin2022
- Author(s)
  Yoshikawa S, Araki M, Lihara Y, Masubuchi M, Yang Y, Morishita S, Imai M, Ydahiro Y, Ando M, Komatsu N
- Organizer
  第84回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08376
[Presentation] 本態性血小板血症合併妊娠の管理2022
- Author(s)
  小松則夫
- Organizer
  第32回日本産婦人科・新生児血液学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Clinical relevance of CREB3L1 expression in Ph-negative MPN2022
- Author(s)
  Soji Morishita, Federico De Marchi, Maho Okuda, Misa Imai, Terumi Baba, Yosuke Mori, Chiho Furuya, Satoko Ogata, Yinjie Yang, Jun Ando, Miki Ando, Marito Araki, Norio Komatsu
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Endogenous expression of MPLW515L showed a weak oncogenic capacity in UT-7/TPO cells.2022
- Author(s)
  Terumi Baba, Nami Masubuchi, Soji Morishita, Kaho Shioiri, Yoshihiko Kihara, Miki Ando, Marito Araki, Norio Komatsu.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08405
[Presentation] Quantitative measurement of mutant calreticulin in specimens of myeloproliferative neoplasm patients2021
- Author(s)
  Satoko Ogata, Marito Araki, Yoshihiko Kihara, Maho Okuda, Soji Morishita, Misa Imai, Nami Masubuchi, Yousuke Mori, Yinjie Yang, Syunpei Yoshikawa, Tomonori Ochiai, Shuichi Shirane, Yoko Edahiro, Jun Ando, Norio Komatsu
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] JAK2 mutation discriminates neoplastic and non-neoplastic polycythemia.2021
- Author(s)
  Mori Y, Araki M, Morishita S, Imai M, Edahiro Y, Ito M, Ochiai T, Shirane S, Hashimoto Y, Ando J, Komatsu N
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08376
[Presentation] Specific expression of CREB3L1 in megakaryocyte in myeloproliferative neoplasms2021
- Author(s)
  Okuda M，Araki M，Federico D，Morishita S，Imai M，Mori Y，Horino M，Ochiai T，Shirame S，Edahiro Y，Ando J，Komatsu N
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Quantitative measurement of mutant calreticulin in specimens of myeloproliferative neoplasm patients.2021
- Author(s)
  Ogata S，Araki M，Kihara Y，Okuda M， Morishita S，Imai M，Masubuchi N，Mori Y，Yinjie Y，Yoshikawa S，Ochiai T，Shirane S， Edahiro Y，Ando J，Komatsu N.
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08405
[Presentation] 海洋天然物由来の新規生理活性タンパク質の構造機能解析2021
- Author(s)
  田中良和, 影山大夢, 辺ひろみ, 増渕菜弥, 中島寛也, 小野寺かこ, 松井崇, 小寺義男, 小川智久, 横山武司, 小松則夫, 荒木真理人, 酒井隆一
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Clinical characteristics of Japanese patients with polycythemia vera: JSH MPN-R18 study results2021
- Author(s)
  枝廣陽子, 橋本由徳, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, 臼杵憲祐, 田中孝幸, 森毅彦, 脇田知志, 齋藤俊樹, 嘉田晃子, 齋藤明子, 下田和哉, 杉本由香, 黒川敏郎, 冨田章裕, 赤司浩一, 松村到, 竹中克斗, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] HEMORRHAGIC EVENTS BUT NOT THROMBOTIC EVENTS CONTRIBUTE TO WORSE SURVIVAL IN PATIENTS WITH ESSENTIAL THROMBOCYTHEMIA: A RETROSPECTIVE NATIONWIDE SURVEY IN JAPAN2021
- Author(s)
  Hashimoto Y, Edahiro Y, Ito T, Gotoh A, Nakamae M, Kimura F, Koike M, Kirito K, Wada H, Usuki K, Tanaka T, Mori T, Wakita S, Saito T, Kada A, Saito A, Shimoda K, Sugimoto Y, Kurokawa T, Tomita A, Akashi K, Matsumura I, Takenaka K, Komatsu N
- Organizer
  26th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] Quantitative measurement of mutant calreticulin in specimens of myeloproliferative neoplasm patients2021
- Author(s)
  Ogata S, Araki M, Kihara Y, Okuda M, Morishita S, Imai M, Masubuchi N, Mori Y, Yang Y, Yoshikawa S, Ochiai T, Shirane S, Edahiro Y, Ando J, Komatsu N
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08376
[Presentation] Marine sponge lectin reveals the mechanism of sugar-chain mediated activation of MPL.2021
- Author(s)
  Watari H，Kageyama H，Nakajia H，Onodera K， Masubuchi N，Oshiro T，Matsui T，Kodera Y， Ogawa T，Hirayama M，Hori K，Yokoyama T， Komatsu N，Araki M，Tanaka Y， Sakai R.
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08405
[Presentation] Quantitative measurement of mutant calreticulin in specimens of myeloproliferative neoplasm patients.2021
- Author(s)
  Satoko Ogata，Marito Araki，Yoshihiko Kihara，Maho Okuda， Soji Morishita，Misa Imai，Nami Masubuchi，Yosuke Mori，Yang Yinjie，Syunpei Yoshikawa，Tomonori Ochiai，Shuichi Shirane， Yoko Edahiro，Jun Ando，Norio Komatsu.
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08424
[Presentation] On the mechanism of sugar-chain mediated activation of thrombopoietin receptor (MPL)2021
- Author(s)
  Hiromi Watari, Hiromu Kageyama, Hiroya Nakajima, Kako Onodera, PJ Foces, Nami Masubuchi, Takashi Matsui, Yoshio Kodera, Tomohisa Ogawa, Makoto Hirayama, Kanji Hori, Takeshi Yokoyama, Douglas Freymann, Norio Komatsu, Marito Araki, Yoshikazu Tanaka, Ryuichi Sakai
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] A NATIONWIDE SURVEY OF JAPANESE PATIENTS WITH POLYCYTHEMIA VERA2021
- Author(s)
  Edahiro Y, Hashimoto Y, Ito T, Gotoh A, Nakamae M, Kimura F, Koike M, Kirito K, Wada H, Usuki K, Tanaka T, Mori T, Wakita S, Saito T, Kada A, Saito A, Shimoda K, Sugimoto Y, Kurokawa T, Tomita A, Akashi K, Matsumura I, Takenaka K, Komatsu N
- Organizer
  26th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] A nationwide survey on Japanese patients with essential thrombocythemia: JSH-MPN-R18 study2021
- Author(s)
  橋本由徳, 枝廣陽子, 伊藤量基, 後藤明彦, 中前美佳, 木村文彦, 小池道明, 桐戸敬太, 和田秀穂, 臼杵憲祐, 田中孝幸, 森毅彦, 脇田知志, 齋藤俊樹, 嘉田晃子, 齋藤明子, 下田和哉, 杉本由香, 黒川敏郎, 冨田章裕, 赤司浩一, 松村到, 竹中克斗, 小松則夫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] Specific expression of CREB3L1 in megakaryocyte in myeloproliferative neoplasms2021
- Author(s)
  Okuda M, Araki M, Federico M, Morishita S, Imai M, Mori Y, Horino M, Ando J, Komatsu N
- Organizer
  第83回日本血液学会
- Data Source
  KAKENHI-PROJECT-21K08376
[Presentation] Distributions of typical non-driver mutations in essential thrombocythemia and polycythemia vera2021
- Author(s)
  Soji Morishita, Yoko Edahiro, Yoshinori Hashimoto, Shuichi Shirane, Tomonori Ochiai, Kyohei Misawa, Tadaaki Inano, Yasutaka Fukuda, Yosuke Mori, Chiho Furuya, Marito Araki, Jun Ando, Norio Komatsu
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] CREB3L1 Overexpresion Can Reliably Discriminate Ph-MPNs From Reactive Cases2020
- Author(s)
  Soji Morishita, Hajime Yasuda, Saya Yamawaki, Hideya Kawaji, Masayoshi Itoh, Yoko Edahiro, Misa Imai, Yasushi Kogo, Satoshi Tsuneda, Akimichi Ohsaka, Yoshihide Hayashizaki, Marito Araki, and Norio Komatsu
- Organizer
  The 63rd American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Therapeutic potential of myeloproliferative neoplasms by antibody targeting mutant calreticulin2020
- Author(s)
  Kihara Y, Araki M, Imai M, Fukuda Y, Mori Y, Taguchi T, Masubuchi N, Mabuchi Y, Yang Y, Mizukami Y, Morishita S, Akazawa C, Ohsaka A, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] MPL Overexpression Induces a High Level of Mutant-Calr/MPL Complex: A Novel Mechanism of Ruxolitinib Resistance in Myeloproliferative Neoplasms with Calr Mutations2020
- Author(s)
  Yasuda S, Aoyama S, Yoshimoto R, Watanabe D, Akiyama H, Yamamoto K, Fujiwara T, Sakaida E, Edahiro Y, Imai M, Araki M, Komatsu N, Kawamata N.
- Organizer
  62nd Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Analysis of behavior of erythropoietin receptor on the cell surface in JAK2 mutant cells2020
- Author(s)
  Shioiri K, Araki M, Kitazawa S, Masubuchi N, Morishita S, Imai M, Ohsaka A, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] CREB3L1 overexpression as a novel diagnostic marker of myeloproliferative neoplasms.2020
- Author(s)
  Morishita S, Yasuda H, Yamawaki S, Kawaji H, Itoh M, Edahiro Y, Imai M, Kogo Y, Tsuneda S, Ohsaka A, Hayashizaki Y, Araki M, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] 典型的なドライバー遺伝子変異の見いだされない本態性血小板血症の特徴2020
- Author(s)
  荒木真理人, 稲野資明, 森下総司, 木原慶彦, 奥田真帆, 楊印杰, 今井美沙, 枝廣陽子, 伊藤雅文, 大佐賀智, 落合友則, 三澤恭平, 大坂顯通, 小松則夫.
- Organizer
  第30回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Therapeutic potential of an antibody targeting the cleaved form of mutant calreticulin in myeloproliferative neoplasms2020
- Author(s)
  Kihara Y, Araki M, Imai M, Mori Y, Horino M, Ogata T, Yoshikawa S, Taguchi T, Masubuchi N, Mabuchi Y, Yang Y, Fukuda Y, Morishita S, Suzuki T, Dohmae N, Shimonaka M, Akazawa C, Ohsaka A, Komatsu N.
- Organizer
  62nd Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Targeting ER stress enhances inhibitory effect of ruxolitinib in mutated-CALR transfected cells2020
- Author(s)
  Moriyama M, Akahane D, Moriya S, Imai M, Araki M, Komatsu N, Miyazawa K, Gotoh A.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Overexpression of MPL causes ruxolitinib-resistance in MPN with CALR frame-shift mutations.2020
- Author(s)
  Yasuda S, Aoyama S, Yoshimoto R, Watanabe D, Yamamoto K, Fujiwara T, Edahiro Y, Imai M, Araki M, Komatsu N, Miura O, Kawamata N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] CREB3L1 overexpression as a novel diagnostic marker of myeloproliferative neoplasms2020
- Author(s)
  Morishita S, Yasuda H, Yamawaki S, Kawaji H, Itoh M, Edahiro Y, Imai M, Kogo Y, Tsuneda S, Ohsaka A, Hayashizaki Y, Araki M, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Therapeutic potential of myeloproliferative neoplasms by antibody targeting mutant calreticulin.2020
- Author(s)
  Kihara Y, Araki M, Imai M, Fukuda Y, Mori Y, Taguchi T, Masubuchi N, Mabuchi Y, Yang Y, Mizukami Y, Morishita S, Akazawa C, Ohsaka A, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] Analysis of behavior of erythropoietin receptor on the cell surface in JAK2 mutant cells.2020
- Author(s)
  Shioiri K, Araki M, Kitazawa S, Masubuchi N, Morishita S, Imai M, Ohsaka A, Komatsu N.
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] CREB3L1 overexpression as a novel diagnostic marker of Philadelphia-negative myeloproliferative neoplasms2020
- Author(s)
  Soji Morishita, Hajime Yasuda, Saya Yamawaki, Hideya Kawaji, Masayoshi Itoh, Yoko Edahiro, Misa Imai, Yasushi Kogo, Satoshi Tsuneda, Akimichi Ohsaka, Yoshihide Hayashizaki, Marito Araki, and Norio Komatsu
- Organizer
  The 82nd Annual Meeting of Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-20H03715
[Presentation] Targeting calreticulin neoantigen for the treatment of myeloproliferative neoplasms2020
- Author(s)
  Araki M, Komatsu N.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] ERストレスはruxolitinibの変異CALR導入細胞増殖抑制効果を増強する2020
- Author(s)
  森山充, 赤羽大悟, 森谷昇太, 山田ありさ, 今井美沙, 荒木真理人, 小松則夫, 宮澤啓介, 後藤明彦:
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] Concomitant occurrence of polyclonal hematopoiesis and cell-autonomous megakaryopoiesis in triple-negative essential thrombocythemia2020
- Author(s)
  Inano T, Araki M, Morishita S, Imai M, Kihara Y, Okuda M, Ito M, Osaga S, Yang Y, Edahiro Y, Ochiai T, Misawa K, Fukuda Y, Ohsaka A, Komatsu N.
- Organizer
  62nd Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] CREB3L1 Overexpression Can Reliably Discriminate Ph-MPNs from Reactive Cases2020
- Author(s)
  Morishita S, Yasuda H, Yamawaki S, Kawaji H, Itoh M, Edahiro Y, Imai M, Kogo Y, Tsuneda S, Akimichi Ohsaka, Hayashizaki Y, Araki M, Komatsu N.
- Organizer
  62nd Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] JAK2 V617Fのコピー数はサイトカイン受容体の活性化に重要である.2019
- Author(s)
  北澤爽汰, 荒木真理人, 塩入香穂, 森下総司, 増渕菜弥, 馬場照美, 山本誠司, 堀内祥行, 今井美沙, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] CALR遺伝子変異による骨髄増殖性腫瘍モデルマウスの作出2019
- Author(s)
  今井美沙, 福田泰隆, 田口鉄平, 三澤恭平, 童紅連, 荒木喜美, 大里元美, 荒木真理人, 大坂顯通, 小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] The impact of allelic burden of JAK2V617F on human hematopoietic cell differentiation.2019
- Author(s)
  枝廣陽子, 竹井拓, ChangLiu, 橳島麻衣, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 骨髄線維化を伴う造血器腫瘍に対する同種造血幹細胞移植の後方視的解析2019
- Author(s)
  白根脩一, 浜埜康晴, 稲野資明, 福田泰隆, 枝廣陽子, 後藤明彦, 小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] 変異型CALRはMPLと分泌経路で相互作用し細胞表面で活性化を引き起こす.2019
- Author(s)
  増渕菜弥, 荒木真理人, 楊印杰, 林英里奈, 今井美沙, 枝廣陽子, 弘中由美, 水上喜久, 木原慶彦, 小池正人, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] 変異型calreticulin特異的配列によるゴルジ体への局在2019
- Author(s)
  水上喜久, 荒木真理人, 今井美沙, 林英里奈, 増渕菜弥, 楊印杰, 木原慶彦, 弘中由美, 大坂顯通, 小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] calreticulin変異による骨髄増殖性腫瘍発症の分子メカニズム2019
- Author(s)
  荒木真理人、楊印杰、増渕菜弥、林英里奈、水上喜久、木原慶彦、今井美沙、弘中由美、橳島麻衣、枝廣陽子、大坂顯通、小松則夫
- Organizer
  第29回日本サイトメトリー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 変異型特異的配列による変異型CALRの細胞内局在の規定.2019
- Author(s)
  水上喜久, 荒木真理人, 今井美沙, 林絵里奈, 増渕菜弥, 楊印杰, 木原慶彦, 弘中由美, 大坂顯通, 小松則夫.
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] Distinctive clinical and molecular features in absolute triple-negative essential thrombocythemia2019
- Author(s)
  Tadaaki Inano、Marito Araki、Soji Morishita、Tomonori Ochiai、Kyohei Misawa、Yasutaka Fukuda、Naoko Midorikawa、Mai Nudejima、Masafumi Ito、Satoshi Osaga、Yoko Edahiro、Misa Imai、Teppei Taguchi、Maho Okuda、Akimichi Ohsaka、Norio Komatsu
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 分泌経路における変異型分子シャペロンとサイトカイン受容体の会合による細胞の腫瘍化2019
- Author(s)
  増渕菜弥、荒木真理人、木原慶彦、楊印杰、今井美沙、水上喜久、林英里奈、弘中由美、竹井拓、枝廣陽子、大坂顯通、小松則夫
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Establishment of a mouse model for mutant CALR myeloproliferative neoplasms2019
- Author(s)
  Misa Imai、Yasutaka Fukuda、Teppei Taguchi、Kyohei Misawa、Honglian Tong、Kimi Araki、Motomi Osato、Akimichi Ohsaka、Marito Araki、Norio Komatsu
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Overexpression of MPL Causes Ruxolitinib-Resistance in Myeloproliferative Neoplasms with Calreticulin Frame-Shift Mutations2019
- Author(s)
  Shunichiro Yasuda、Satoru Aoyama、Ryoto Yoshimoto、Watanabe Daisuke、Hiroki Akiyama、Yoshihiro Umezawa、Ayako Nogami、Kouhei Yamamoto、Takeo Fujiwara、Yoko Edahiro Marito Araki、Norio Komatsu、Tetsuya Fukuda、Ayako Arai、Osamu Miura、Norihiko Kawamata
- Organizer
  61th Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 変異型特異的配列による変異型CALRの細胞内局在の規定2019
- Author(s)
  水上喜久、荒木真理人、今井美沙、林英里奈、増渕菜弥、楊印杰、木原慶彦、弘中由美、大坂顯通、小松則夫
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] Mutations in epigenetic and splicing related genes among Japanese overt and prefibrotic primary myelofibrosis using target seuencing2019
- Author(s)
  Soji Morishita、Tomonori Ochiai、Kyohei Misawa、Tadaaki Inano、Yasutaka Fukuda、Yasumitsu Kurokawa、Yoko Edahiro、Marito Araki、Akimichi Ohsaka、Norio Komatsu
- Organizer
  The 10th JSH International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 真正トリプルネガティブ本態性血小板血症における臨床的・分子生物学的特異性.2019
- Author(s)
  稲野資明, 荒木真理人, 森下総司, 落合友則, 三澤恭平, 福田泰隆, 緑川直子, 橳島麻衣, 伊藤雅文, 大佐賀智, 枝廣陽子, 今井美沙, 田口鉄平, 奥田真帆, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型CALRはMPLと分泌経路で相互作用し細胞表面で活性化を引き起こす2019
- Author(s)
  増渕菜弥, 荒木真理人, 楊印杰, 林英里奈, 今井美沙, 枝廣陽子, 弘中由美, 水上喜久, 木原慶彦, 小池正人, 大坂顯通, 小松則夫
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] 分泌経路における変異型分子シャぺロンとサイトカイン受容体の会合による細胞の腫瘍化.2019
- Author(s)
  増渕菜弥, 荒木真理人, 木原慶彦, 楊印杰, 今井美沙, 水上喜久, 林英里奈, 弘中由美, 竹井拓, 枝廣陽子, 大坂顯通, 小松則夫.
- Organizer
  第29回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] Oncogenic activation of thrombopoietin receptor by mutant calreticulin on cell surface2019
- Author(s)
  Marito Araki、Norio Komatsu
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 心筋梗塞・脳梗塞患者におけるJAK2 V617F変異の頻度.2019
- Author(s)
  筒井深雪, 森下総司, 西野隆, 枝廣陽子, 常田聡, 荒木真理人, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 非ドライバー変異と予後予測システムDIPSS/DIPSS-plus.2019
- Author(s)
  森下総司, 落合友則, 三澤恭平, 大佐賀智, 稲野資明, 福田泰隆, 黒川安満, 枝廣陽子, 橳島麻衣, 緑川直子, 荒木真理人, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型calreticulin特異的配列によるゴルジ体への局在.2019
- Author(s)
  水上喜久, 荒木真理人, 今井美沙, 林英里奈, 増渕菜弥, 楊印杰, 木原慶彦, 弘中由美, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] 抗TfR1抗体による真性多血症内因性赤芽球コロニーの形成阻害.2019
- Author(s)
  木原慶彦, 増渕菜弥, 張黎臨, 荒木真理人, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Mutations in epigenetic and splicing related genes among japanese overt and prefibrotic primary myelofibrosis using target sequencing.2019
- Author(s)
  Morishita S, Ochiai T, Misawa K, Inano T, Fukuda Y, Kurokawa Y, Edahiro Y, Araki M, Ohsaka A, Komatsu N.
- Organizer
  The 10th JSH INTERNATIONAL SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Mutant specific sequence promotes accumulation of mutant CALR in the Golgi apparatus2019
- Author(s)
  Yoshihisa Mizukami、Marito Araki、Misa Imai、Erina Hayashi、Nami Masubuchi、Yinjie Yang、Yoshihiko Kihara、Yumi Hironaka、Akimichi Ohsaka、Norio Komatsu
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] JAK2アレルバーデンの高い患者は血小板コントロールが良好でもvWF活性低値のリスクが高い.2019
- Author(s)
  飯塚和秀, 入山規良, 森下総司, 三浦勝浩, 飯塚芳一, 西崎祐史, 柳澤尚武, 安藤純, 内野慶人, 高橋宏通, 中川優, 濱田高志, 八田善弘, 中山智祥, 武井正美, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 真性多血症患者由来iPS細胞におけるJAK2 V617F変異の修正.2019
- Author(s)
  枝廣陽子, 劉暢, 荒木真理人, 橳島麻衣, 森下総司, 今井美沙, 増渕菜弥, 水上喜久, 眞野修一, 竹井拓, 大坂顯通, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] UT-7とともに歩んだ血液人生.2019
- Author(s)
  小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Mutant calreticulin interacts with MPL in the secretion pathway for the activation on cell surface.2019
- Author(s)
  Nami Masubuchi、Marito Araki、Yinjie Yang、Erina Hayashi、Misa Imai、Yoko Edahiro、Yumi Hironaka、Yoshihisa Mizukami、Yoshihiko Kihara、Masato Koike、Akimichi Ohsaka、Norio Komatsu
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08848
[Presentation] 骨髄増殖性腫瘍の最前線～本態性血小板血症を中心に.2019
- Author(s)
  小松則夫.
- Organizer
  輸血細胞治療学会九州支部会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 腫瘍随伴性血管炎を合併した真性多血症.2019
- Author(s)
  福田泰隆, 枝廣陽子, 森下総司, 筒井深雪, 新田英昭, 安藤純, 荒木真理人, 小松則夫.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Copy number of JAK2V617F modulates human hematopoietic cell differentiation.2018
- Author(s)
  Edahiro Y, Mano S, Takei H, Li L, Morishita S, Gotoh A, Tsuneda S, Ohsaka A, Araki M, Komatsu N.
- Organizer
  8th International Conference on Myeloproliferative Neoplasms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Boarding on the secretary pathway is required for the oncogenic property of mutant calreticulin.2018
- Author(s)
  Araki M, Masubuchi N, Hayashi E, Yang Y, Imai M, Kihara Y, Mizukami Y, Hironaka Y, Edahiro Y, Ohsaka A, Komatsu N.
- Organizer
  23rd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] APL細胞の分化誘導におけるATRA標的遺伝子の同定.2018
- Author(s)
  角南義孝, 荒木真理人, 山本誠司, 堀内祥行, 辻岡一也, 薫茂, 今井美沙, 森下総司, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] 変異型 CALRの多量体化は MPLとの結合と活性化に必須である.2018
- Author(s)
  荒木真理人, 楊印杰, 今井美沙, 水上喜久, 木原慶彦, 角南義孝, 増渕菜弥, 枝廣陽子, 弘中由美, 大佐賀智, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Interferon therapy for pregnant patients with myeloproliferative neoplasms.2018
- Author(s)
  Edahiro Y, Gotoh A, Ando J, Tsutsui M, Morishita S, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] トリプルネガティブ本態性血小板血症症例の臨床像と遺伝子変異.2018
- Author(s)
  稲野資明, 荒木真理人, 福田泰隆, 森下総司, 落合友則, 三澤恭平, 伊藤雅文, 山本紘司, 楊印杰, 田口鉄平, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 細胞減少療法はPMF患者における腎機能の悪化を防止する.2018
- Author(s)
  福田泰隆, 荒木真理人, 山本紘司, 森下総司, 稲野資明, 三澤恭平, 落合友則, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Boarding on the secretary pathway is required for the oncogenic property of mutant calreticulin.2018
- Author(s)
  Araki M, Masubuchi N, Hayashi E, Yang Y, Imai M, Kihara Y, Mizukami Y, Hironaka Y, Edahiro Y, Ohsaka A, Komatsu N.
- Organizer
  23rd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Clinical and molecular features of patients with triple-negative essential thrombocythemia.2018
- Author(s)
  Inano T, Araki M, Fukuda Y, Morishita S, Ochiai T, Misawa K, Ito M, Yamamoto K, Yang Y, Taguchi T, Edahiro Y, Imai M, Gotoh A, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] The Zygosity of JAK2V617F Determines the Disease Entities of Myeloproliferative Neoplasms By Modulating Erythropoiesis but Not Megakaryopoiesis2018
- Author(s)
  Takei H, Edahiro Y, Li L, Mizukami Y, Imai M, Morishita S, Ohsaka A, Araki M, Komatsu N.
- Organizer
  60th Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] トリプルネガティブ本態性血小板血症症例の臨床像と遺伝子変異.2018
- Author(s)
  稲野資明, 荒木真理人, 福田泰隆, 森下総司, 落合友則, 三澤恭平, 伊藤雅文, 山本紘司, 楊印杰, 田口鉄平, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] Introduction of CALR and JAK2 V617F mutations to UT-7/Epo and K562 by the CRISPR/Cas9 system.2018
- Author(s)
  Yasuda S, Aoyama S, Watanabe D, Araki M, Komatsu N, Miura O, Kawamata N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Interferon therapy for pregnant patients with myeloproliferative neoplasms.2018
- Author(s)
  Edahiro Y, Gotoh A, Ando J, Tsutsui M, Morishita S, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] JAK2V617F変異アレル数はヒト血球分化を変化させる.2018
- Author(s)
  竹井拓, 枝廣陽子, 李麗華, 水上喜久, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 骨髄線維化を伴う骨髄異形成症候群の臨床病態および分子発症機序の解明.2018
- Author(s)
  新谷直樹, 原田浩徳, 原田結花, 飯塚弘子, 森下総司, 荒木真理人, 大坂顯通, 土岐典子, 大橋一輝, 萩原政夫, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] JAK2V617F変異アレル数はヒト血球分化を変化させる.2018
- Author(s)
  竹井拓, 枝廣陽子, 李麗華, 水上喜久, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Boarding on the secretary pathway is required for the oncogenic property of mutant calreticulin2018
- Author(s)
  Araki M, Masubuchi N, Hayashi E, Yang Y, Imai M, Kihara Y, Mizukami Y, Hironaka Y, Edahiro Y, Ohsaka A, Komatsu N.
- Organizer
  23rd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] 受容体活性化において野生型JAK2は変異型JAK2を抑制しているようである.2018
- Author(s)
  北澤爽汰, 荒木真理人, 森下総司, 楊印杰, 今井美沙, 大坂顕通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型 CALRの多量体化は MPLとの結合と活性化に必須である.2018
- Author(s)
  荒木真理人, 楊印杰, 今井美沙, 水上喜久, 木原慶彦, 角南義孝, 増渕菜弥, 枝廣陽子, 弘中由美, 大佐賀智, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08372
[Presentation] ターゲット遺伝子シーケンスパネルによる原発性骨髄線維症の遺伝子変異解析.2018
- Author(s)
  森下総司, 落合友則, 三澤恭平, 稲野資明, 橳島麻衣, 大坂顕道, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型分子シャペロンによるサイトカイン受容体活性化の分子メカニズム2018
- Author(s)
  荒木真理人, 小松則夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] 変異型CALRの多量体化はMPLとの結合と活性化に必須である2018
- Author(s)
  荒木真理人, 楊印杰, 今井美沙, 水上喜久, 木原慶彦, 角南義孝, 増渕菜弥, 枝廣陽子, 弘中由美, 大佐賀智, 大坂顯通, 小松則夫
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Copy number of JAK2V617 modulates human hematopoietic cell differentiation .2018
- Author(s)
  Edahiro Y, Mano S, Takei H, Li L, Morishita S, Gotoh A, Tsuneta S, Osaka A, Araki M, Komatsu N
- Organizer
  8th International Conference on Myeloproliferative Neoplasms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] Wild-type JAK2 may suppress mutant JAK2 activity in cytokine receptor activation.2018
- Author(s)
  Kitazawa S, Araki M, Morishita S, Yang Y, Imai M, Ohsaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Cytoreductive therapy prevents worsening of renal function in patients with primary myelofibrosis.2018
- Author(s)
  Fukuda Y, Araki M, Imamoto K, Morishita S, Inano T, Misawa K, Ochiai T, Edahiro Y, Imai M, Gotoh A, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] The Zygosity of JAK2V617F Determines the Disease Entities of Myeloproliferative Neoplasms By Modulating Erythropoiesis but Not Megakaryopoiesis.2018
- Author(s)
  Takei H, Edahiro Y, Li L, Mizukami Y, Imai M, Morishita S, Ohsaka A, Araki M, Komatsu N.
- Organizer
  ASH 60th Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] SLAMF7high CD16negative Monocytes Increase in Peripheral Blood of Patients with Myelofibrosis in Correlation with JAK2V617F Mutation2018
- Author(s)
  Maekawa T, Kato S, Okada Y, Tachi N, Teramoto M, Kawamura T, Osawa Y, Kobayashi S, Sato K, Hashimoto M, Suzu S, Usuki K, Morishita S, Araki M, Komatsu N, Kimura F.
- Organizer
  60th Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Copy number of JAK2V617 modulates human hematopoietic cell differentiation .2018
- Author(s)
  Edahiro Y, Mano S, Takei H, Li L, Morishita S, Gotoh A, Tsuneta S, Osaka A, Araki M, Komatsu N
- Organizer
  8th International Conference on Myeloproliferative Neoplasms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] UT-7/EpoおよびK562に対するCRISPR/Cas9法を用いたCALRおよびJAK2V617F変異の導入.2018
- Author(s)
  安田峻一郎, 青山慧, 渡邊大介, 荒木真理人, 小松則夫, 三浦修, 川又紀彦.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] トリプルネガティブ本態性血小板血症症例の臨床像と遺伝子変異.2018
- Author(s)
  稲野資明, 荒木真理人, 福田泰隆, 森下総司, 落合友則, 三澤恭平, 伊藤雅文, 山本紘司, 楊印杰, 田口鉄平, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Cytoreductive therapy prevents worsening go renal function in patients with primary myelofibrosis.2018
- Author(s)
  Fukuda Y, Araki M, Imamoto K, Morishita S, Inano T, Misawa K, Ochiai T, Edahiro Y, Imai M, Gotoh A, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] Clinical and molecular features of patients with triple-negative essential thrombocythemia.2018
- Author(s)
  Inano T, Araki M, Fukuda Y, Morishita S, Ochiai T, Misawa K, Ito M, Yamamoto K, Yang Y, Taguchi T, Edahiro Y, Imai M, Gotoh A, Osaka A, Komatsu N.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06690
[Presentation] 細胞減少療法はPMF患者における腎機能の悪化を防止する.2018
- Author(s)
  福田泰隆, 荒木真理人, 山本紘司, 森下総司, 稲野資明, 三澤恭平, 落合友則, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Copy number of JAK2V617F modulates human hematopoietic cell differentiation2018
- Author(s)
  Edahiro Y, Mano S, Takei H, Morishita S, Tsuneda S, Ohsaka A, Araki M, Komatsu N.
- Organizer
  8th International Conference on Myeloproliferative Neoplasms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] 変異型 CALR タンパク質の発現を制御するメカニズム.2017
- Author(s)
  木原慶彦, 荒木真理人, 楊印杰, 今井美沙, 増渕菜弥, 水上喜久, 弘中由美, 竹井拓, 枝廣陽子, 大坂顯通, 小松則夫.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型CALRの細胞内コンパートメントへの局在がトロンボポエチン受容体の活性化に必要である.2017
- Author(s)
  Araki M, Komatsu N.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Engagement of mutant calreticulin and MPL in a cellular compartment is required for MPL activation.2017
- Author(s)
  Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Soji Morishita, Yoshihiko Kihara, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] 家族性骨髄増殖性腫瘍患者からの iPS細胞株の樹立.2017
- Author(s)
  眞野修一, 竹井拓, 森下総司, 水上喜久, 増渕菜弥, 弘中由美, 橳島麻衣, 常田聡, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] マウス胎仔における造血幹細胞依存性および非依存性の血球系譜の発生起源.2017
- Author(s)
  横溝智雅, 渡邊直紀, 森誠一, 髙久智生, 大里元美, 小松則夫.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Skewed megakaryopoiesis observed in hematopoietic progenitor cells harboring calreticulin mutation.2017
- Author(s)
  Takei H, Mano S, Masubuchi N, Mizukami Y, Morishita S, Imai M, Edahiro Y, Hironaka Y, Nudejima M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.
- Organizer
  2017年度　生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] 変異型 CALR による巨核球分化偏向性は GATA2 の発現亢進と相関している.2017
- Author(s)
  竹井拓, 眞野修一, 増渕菜弥, 水上喜久, 今井美沙, 森下総司, 枝廣陽子, 弘中由美, 橳島麻衣, 遠藤大, 中村壮, 江藤浩之, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  第79回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Engagement of mutant calreticulin and MPL in a cellular compartment is required for MPL activation.2017
- Author(s)
  Masubuchi N, Araki M, Hayashi E, Yang Y, Imai M, Mizukami Y, Hironaka Y, Takei H, Morishita S, Kihara Y, Edahiro Y, Ohsaka A, Komatsu N.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Establishment of an in vitro model for the skewed megakaryopoiesis by calreticulin mutation in human cells.2017
- Author(s)
  Takei H, Mano S, Masubuchi N, Mizukami Y, Morishita S, Imai M, Edahiro Y, Hironaka Y, Nudejima M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N
- Organizer
  22nd Congress European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] BCR-JAK2 陽性骨髄増殖性腫瘍.2017
- Author(s)
  筒井深雪, 後藤明彦, 森下総司, 荒木真理人, 福田泰隆, 新田英昭, 安藤純, 小松則夫.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 骨髄増殖性腫瘍に見出される変異型 CALR 蛋白質の細胞内局在2017
- Author(s)
  林英里奈, 荒木真理人, 増渕菜弥, 水上喜久, 楊印杰, 今井美沙 , 弘中由美, 竹井拓, 木原慶彦, 枝廣陽子, 大坂顯通, 小松則夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Establishment of an in vitro model for the skewed megakaryopoiesis by calreticulin mutation in human cells.2017
- Author(s)
  Takei H, Mano S, Masubuchi N, Mizukami Y, Morishita S, Imai M, Edahiro Y, Hironaka Y, Nudejima M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.
- Organizer
  22nd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Skewed megakaryopoiesis by mutant calreticulin is associated with increased GATA2 expression2017
- Author(s)
  Hiraku Takei, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Misa Imai, Soji Morishita, Yoko Edahiro Yumi Hironaka Mai Nudejima Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] 家族性骨髄増殖性腫瘍患者からの iPS 細胞株の樹立.2017
- Author(s)
  眞野修一, 竹井拓, 森下総司, 水上喜久, 増渕菜弥, 弘中由美, 橳島麻衣 ,常田聡, 大坂顯通, 荒木真理人, 小松則夫
- Organizer
  第 79 回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] Localization of mutant calreticulin in the Golgi apparatus is required for its oncogenic capacity2017
- Author(s)
  Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai Yoshihiko Kihara, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
- Organizer
  59th Annual Meeting & Exposition of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] カルレチキュリン変異を有する血球前駆細胞は巨核球への分化偏向性を有する.2017
- Author(s)
  竹井拓, 眞野修一, 増渕菜弥, 水上喜久, 今井美沙, 森下総司, 枝廣陽子, 弘中由美, 橳島麻衣, 常田聡, 遠藤大, 中村壮, 江藤浩之, 大坂顯通, 荒木真理人, 小松則夫.
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 変異型CALRの細胞内コンパートメントへの局在がトロンボポエチン受容体の活性化に必要である2017
- Author(s)
  荒木真理人, 小松則夫
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] iPS 細胞由来若返りCTL 治療のためのCD8b の役割.2017
- Author(s)
  崎山祐未, 安藤美樹, 村越勇人, 安藤純, 大坂顯通, 小松則夫, 滝口雅文, 中内啓光.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] 骨髄増殖性腫瘍に見出される変異型 CALR 蛋白質の細胞内局在.2017
- Author(s)
  林英里奈, 荒木真理人, 増渕菜弥, 水上喜久, 楊印杰, 今井美沙, 弘中由美, 竹井拓, 木原慶彦, 枝廣陽子, 大坂顯通, 小松則夫.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Localization of Mutant Calreticulin in the Golgi Apparatus Is Required for Its Oncogenic Capacity.2017
- Author(s)
  Masubuchi N, Araki M, Hayashi E, Yang Y, Imai M, Kihara Y, Mizukami Y, Hironaka Y, Takei H, Edahiro Y, Ohsaka A, Komatsu N.
- Organizer
  59th Annual Meeting of the American Society of Hematology and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Mechanisms governing the accumulation of mutant calreticulin2017
- Author(s)
  Yoshihiko Kihara, Marito Araki, Yinjie Yang, Misa Imai, Nami Masubuchi, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Engagement of mutant calreticulin and MPL in a cellular compartment is required for MPL activation2017
- Author(s)
  Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Soji Morishita, Yoshihiko Kihara, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Clinical Performance Study of a novel JAK2V617F mutation quantitative kits for patients with Ph-MPN.2017
- Author(s)
  野口雅章, 小松則夫, 小池道明, 木崎昌弘, 片山直之, 土橋史明, 薄井紀子, 桐戸敬太.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04211
[Presentation] Mutant Calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms.2017
- Author(s)
  Marito Araki, Yinjie Yang, Nami Masubuchi, Yoshihisa Mizukami, Misa Imai, Erina Hayashi, Yumi Hironaka, Soji Morishita, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
- Organizer
  The annual GAP Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Establishment of an in vitro model for the skewed megakaryopoiesis by calreticulin mutation in human cells2017
- Author(s)
  Hiraku Takei, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Soji Morishita, Misa Imai, Yoko Edahiro, Yumi Hironaka, Mai Nudejima, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
- Organizer
  22nd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Skewed megakaryopoiesis by mutant calreticulin is associated with increased GATA2 expression.2017
- Author(s)
  Takei H, Mano S, Masubuchi N, Mizukami Y, Imai M, Morishita S, Edahiro Y, Hironaka Y, Nudejima M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] Myeloproliferative neoplasm with BCR-JAK2 fusion2017
- Author(s)
  Tsutsui M, Gotoh , Morishita S, Araki M, Fukuda Y, Nitta H, Ando J, Komatsu N.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Differential clinical features by subtypes of Calreticulin mutation in myeloproliferative neoplasms2016
- Author(s)
  Misawa K, Araki M, Ochiai T, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Sunami S, Gotoh A, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N
- Organizer
  21st Congress European hematology association
- Place of Presentation
  Copenhagen
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] Evaluation of the dose and efficacy of ruxolitinib in Japanese patients with myelofibrosis2016
- Author(s)
  Kirito K, Okamoto S, Shishi K, Tauchi T, Handa H, Saito S, Takenaka K, Shimoda K, Ogitani K, Komatsu N, Okada H, Amagasaki T, Suzuki K Yonezo T, Akashi K
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] 骨髄増殖性腫瘍細胞において変異型Calreticulinはトロンボポエチン受容体と相互作用しJAK2を活性化する2016
- Author(s)
  荒木真理人, 小松則夫
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Clinical characteristics of BCSH criteria defined PV and ET patients in Japan2016
- Author(s)
  Ochiai M, Araki M, Misawa K, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Sunami Y, Goth A, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Mutant calreticulin activate the thrombopoietin receptor in myeloproliferative neoplasm2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N.
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] 骨髄増殖生腫瘍を引き起こす変異型Calreticulinの細胞内局在.2016
- Author(s)
  増渕菜弥、荒木真理人、楊印杰、弘中由美、竹井拓、森下総司、今井美沙、水上喜久、カンシン、大坂顯通、小松則夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] 骨髄増殖生腫瘍を引き起こす変異型Calreticulinの細胞内局在2016
- Author(s)
  増渕菜弥, 荒木真理人, Yinjie Yang, 弘中由美, 竹井拓, 森下総司, 今井美沙, 水上喜久, Kan Shin、大坂顯通, 小松則夫.
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Mutant Calreticulin activates JAK2 by an interaction with thrombopoietin receptor in myeloproliferative neoplasm cells.2016
- Author(s)
  Araki M, Komatsu N.
- Organizer
  第75回日本癌学会学術総会.
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Modeling MPN phenotypes in vitro by using iPSC harboring CALR ins5 mutation2016
- Author(s)
  Takei T, Masubuchi N, Mano S, Araki M, Morishita S, Mizukami Y, Kan S, Edahiro Y, Sunami Y, Hironaka Y, Endo H, Nakamura S, Eto K, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Mutant Calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms.2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Modeling MPN phenotypes in vitro by using iPSC harboring CALR ins5 mutation.2016
- Author(s)
  Takei H, Masubuchi N, Mano S, Araki M, Morishita S, Mizukami Y, Kan S, Edahiro Y, Sunami Y, Hironaka Y, Endo H, Nakamura S, Eto K, Ohsaka A, Komatsu N.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Cell surface localization of mutant calreticulin that induces myeloproliferative neoplasms (MPNs)2016
- Author(s)
  Masubuchi N, Araki M, Yang Y, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Ohsaka A, Komatsu N
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] Cell surface localization of mutant calreticulin that induces myeloproliferative neoplasms (MONs)2016
- Author(s)
  Masubuchi N, Araki M, Yang Y, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] ビノレルビンは乳癌細胞株においてアグリソーム形成を阻害することによりボルテゾミブ誘導性の細胞毒性を増強する2016
- Author(s)
  宮原か奈, 森谷昇太, 小松誠一郎, 平澤一浩, 阿部晃久, 平本正樹, 石川孝, 宮澤啓介
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Cell surface localization of mutant Calreticulin that induces myeloproliferative neoplasms (MPNs).2016
- Author(s)
  Masubuchi N, Araki M, Yang Y, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Ohsaka A, Komatsu N.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms.2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N.
- Organizer
  21st Congress of the European Hematology Association.
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2016-06-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09859
[Presentation] Modeling MPN phenotypes in vitro by using iPSC harboring CALR ins5 mutation,2016
- Author(s)
  Takei H, Masubuchi N, Mano S, Araki M, Morishita S, Mizukami Y, Kan S, Edahiro Y, Sunami Y, Hironaka Y, Endo H, Nakamura S, Eto K, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K19587
[Presentation] Impact of mutations on efficacy of anagrelide in Japanese patients with essential thrombocythemia2016
- Author(s)
  Tsutsui M, Gotoh, A Araki M, Morishita S, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Mutant calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms2016
- Author(s)
  Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Osaka A, Komatsu N
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Early disease onset of patients with triple-negative myeloproliferative neoplasms2015
- Author(s)
  白根脩一, 荒木真理人, 森下総司, 枝廣陽子, 竹井拓, 津村真知子, 弘中由美, 落合友則, 三澤恭平, 大坂顯通, 小松則夫
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂、ANAクラウンプラザホテル金沢、ホテル日航金沢、ホテル金沢、金沢市アートホール、もてなしドーム（石川県、金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Establishment of iPS cells from myeloproliferative neoplasms patients with CALR mutation2015
- Author(s)
  竹井拓, 森下総司, 荒木真理人, 水上喜久, 枝廣陽子, 角南義孝, 弘中由美, 津村真知子, 常田聡, 遠藤大, 中村壮, 江藤浩之, 大坂顯通, 小松則夫
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂、ANAクラウンプラザホテル金沢、ホテル日航金沢、ホテル金沢、金沢市アートホール、もてなしドーム（石川県、金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] A interim analysis of stop trial against CMP-CP in CMR patients who had received sequential TKIs2015
- Author(s)
  佐藤恵理子，森下総司，野口雅章，小池道明，大津洋，小松則夫
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県，金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25460699
[Presentation] Assessing the Safety and Efficacy of Ruxolitinib in a Multicenter, Open-Label, Expanded-Access Study in Japanese Patients with Myelofibrosis (MF)2015
- Author(s)
  Keita Kirito, Norio Komatsu, Kazuya Shimoda, Hikaru Okada, Taro Amagasaki, Toshio Yonezu, Koichi Akashi
- Organizer
  第57回米国血液学会議
- Place of Presentation
  Orland,Florida, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] A highly specific method for detecting a single copy JAK2V617F mutation2015
- Author(s)
  森下総司, 荒木真理人, 弘中由美, 角南義孝, 枝廣陽子, 筒井深雪, 大坂顯通, 小松則夫
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂、ANAクラウンプラザホテル金沢、ホテル日航金沢、ホテル金沢、金沢市アートホール、もてなしドーム（石川県、金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Activation of AP-1 By JAK2V617F through Induction and Stabilization of c-FOS2015
- Author(s)
  Yoko Edahiro, Marito Araki, Yumi Hironaka, Yinjie Yang, Soji Morishita, Yoshitaka Sunami, Akimichi Ohsaka, Norio Komatsu
- Organizer
  第57回米国血液学会議
- Place of Presentation
  Orland,Florida, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07972
[Presentation] Management of adult chronic immune thrombocytopenia in JAPAN : Patient and hematologist perspective2013
- Author(s)
  Tsukune Y, Edahiro Y, Komatsu N
- Organizer
  The 18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23591407
[Presentation] Identification of FOXO3A as a key downstream target for the oncogenic JAK2V617F2013
- Author(s)
  Kobayashi M, Araki M, Hironaka Y, Ohsaka A, Komatsu N
- Organizer
  55th Annual Meeting of the American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591407
[Presentation] The Sirtuin inhibitor induces APL cell differentiation2012
- Author(s)
  Sunami Y, Araki M,Morishita S,Hironaka Y,Edahiro Y,Ohsaka A,Komatsu N
- Organizer
  The 3rd JSH International Symposium 2012
- Place of Presentation
  Kawagoe, Japan
- Data Source
  KAKENHI-PROJECT-23591407
[Presentation] Lipid RaftはリツキシマブによるHIF-1活性化を規定する2011
- Author(s)
  野崎由美、Qiao Qiao、迫江公己、小松則夫、桐戸敬太
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌市
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] The SirT1 Inhibitor Tenovin-6 Induces Monocytic Differentiation in APL Cells2011
- Author(s)
  角南義孝、小松則夫, 他
- Organizer
  53回米国血液学会(53rd.ASH annual meeting)
- Place of Presentation
  サンディェゴ
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PUBLICLY-23118528
[Presentation] Rituximab Activation of AKTand Pathways Is Dependent on Membrane Lipid Raft Cholesterol Levels in Lymphoma Cells2011
- Author(s)
  Nozaki Y, Mitsumori T, Komatsu N, Kirito K
- Organizer
  第53回米国血液学会
- Place of Presentation
  SanDiego
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] The membrane cholesterollevels of B cell lymphoma cells determine rituximab-induced AKT activation2011
- Author(s)
  Nozaki Y, Mitsumori T, Komatsu N, Kirito K
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] MPN細胞において、低酸素状態はSHP-2誘導を介しJAK2V617Fの活性化を阻害する2011
- Author(s)
  三森徹、野崎由美、川島一郎、山本健夫、濱中聡至、中嶌圭、小松則夫、桐戸敬太
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] 真性赤血球増加症における血栓症のリスク解析2011
- Author(s)
  山本健夫、三森徹、川島一郎、濱中聡至、野崎由美、中嶌圭、小松則夫、桐戸敬太
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] Hypoxia Blocks Activation of JAK2V617F Through Suppression of SHP-2 Expression in MPN cells2011
- Author(s)
  Mitsumori T, Nozaki Y, Komatsu N, Kirito K
- Organizer
  第53回米国血液学会
- Place of Presentation
  SanDiego
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] 治療難治性であったTリンパ芽球性リンパ腫の一例2010
- Author(s)
  雨宮憲彦,小岩井孝夫,風間文智,畑山一貴,遠藤武,高野勝弘,三森徹,桐戸敬太,小松則夫,尾崎由基男
- Organizer
  第11回日本検査血液学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] 膵癌が疑われた膵臓原発の髄外性形質細胞腫の1例2010
- Author(s)
  沼田裕樹,小佐野雅識,川島一郎,中嶌圭,野崎由美,山本健夫,三森徹,小松則夫,桐戸敬太
- Organizer
  第573回日本内科学会関東地方会例会
- Place of Presentation
  東京都
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] リツキシマブによるHIF-1活性化にはLipid Raftが関与する2010
- Author(s)
  野崎由美、Qiao Qiao、迫江公己、小松則夫、桐戸敬太
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] 低酸素によるJAK2V617F活性制御2010
- Author(s)
  三森徹、野崎由美、小松則夫、桐戸敬太
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] リツキシマブはHIF-1を介して抗アポトーシス蛋白Survivinを誘導する2009
- Author(s)
  野崎由美,桐戸敬太, QiaoQiao,迫江公己,小松則夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都府
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] たこつぼ型心筋症を発症した多発性骨髄腫2009
- Author(s)
  三森徹,中嶌圭,野崎由美,濱中聡至,永嶋貴博,岩尾憲明,桐戸敬太,小松則夫
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都府
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21591197
[Presentation] HIF-1 Prevents Hematopoietic Cells from Cell Damage by Overproduction of Mitochondrial ROS after Cytokine Stimulation through Induction of PDK-12008
- Author(s)
  1.Kirito K, Yoshida K, Hu Y, Qiao Q, Sakoe K, Komatsu N.
- Organizer
  第50回米国血液学会
- Place of Presentation
  San Fransico
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19591103
[Presentation] HIF-1 Prevents Hematopoietic Cells from Cell Damage by Overproduction of Mitochondrial ROS after Cytokine Stimulation through Induction of PDK-12008
- Author(s)
  Kirito, K., Yoshida, K., Yongzhen H., Qiao Q., Sakoe, K., Komatsu, N.
- Organizer
  50 th Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19591103
[Presentation] HIF-1 Prevents Hematopoietic Cells from Cell Damage by Overproduction of Mitochondrial ROS after Cytokine Stimulation through Induction of PDK-12008
- Author(s)
  Keita Kirito, Kozue Yoshida, Yongzhen Hu, Qiao Qiao, Kumi Sakoe, and Norio Komatsu
- Organizer
  第50回米国血液学会
- Place of Presentation
  San Francisco
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-18390282
[Presentation] HIF-1 Supports the Survival of Multiple Myeloma Cells through the Induction of Survivin Gene2007
- Author(s)
  Kirito, K. Yongzhen, Hu., Yoshida, K., Mitsumori, T., Nakajima, K., Nozaki, Y., Nagashima, T., Kunitamae, M., Sakoe, K., Komatsu, N.
- Organizer
  49th Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, GA, USA
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-19591103
[Presentation] ATRA induces APL cell granulocytic differentiation through the PCAF overexpression.
- Author(s)
  Yoshitaka Sunami, Marito Araki, Akihiro Ito, Yumi Hironaka, Akimichi Ohsaka, Minoru Yoshida, Norio Komatsu
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PUBLICLY-25118725
[Presentation] Histone acetyltransferase PCAF is required for ATRA-induced granulocytic differentiation in acute promyelocytic leukemia cells.
- Author(s)
  Yoshitaka Sunami, Marito Araki, Akihiro Ito, Yumi Hironaka, Akimichi Ohsaka, Minoru Yoshida, Norio Komatsu
- Organizer
  American Society of Hematology 56th Annual Meeting
- Place of Presentation
  San Francisco, US
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PUBLICLY-25118725
[Presentation] Histone acetyltransferase PCAF is required for ATRA-induced granulocytic differentiation in APL cells.
- Author(s)
  Yoshitaka Sunami, Marito Araki, Akihiro Ito, Yumi Hironaka, Akimichi Ohsaka, Minoru Yoshida, Norio Komatsu
- Organizer
  International Society of Hematology 35th World Congress 2014
- Place of Presentation
  Beijing, China
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PUBLICLY-25118725

1. KIRITO Keita (90306150)

# of Collaborated Projects: 13 results

# of Collaborated Products: 40 results
2. ARAKI MARITO (80613843)

# of Collaborated Projects: 12 results

# of Collaborated Products: 146 results
3. UCHIDA Mie (80316520)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
4. 今井美沙 (50709003)

# of Collaborated Projects: 6 results

# of Collaborated Products: 24 results
5. MORI Masaki (00337346)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. MIURA Yasusada (60048965)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. 森下総司 (10635866)

# of Collaborated Projects: 5 results

# of Collaborated Products: 51 results
8. TSHIMA Masaki (00306151)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. KASHII Yoshifumi (10271222)

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10. SAKOE Kumi (10398505)

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11. SUDA Toshio (60118453)

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12. IMAGAWA Shigehiko (60231164)

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13. MUROI Kazuo (50190939)

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14. HATAKE Kiyohiko (80192699)

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15. SHIMIZU Ritsuko (40226262)

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16. KUNITAMA Masae (60397297)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. SATO Yuko (10137713)

# of Collaborated Projects: 2 results

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18. TAKAGI Shojiro (20158992)

# of Collaborated Projects: 2 results

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19. TAKATOKU Masaaki (20285787)

# of Collaborated Projects: 2 results

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20. KUSANO Eiji (50102249)

# of Collaborated Projects: 2 results

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21. Gotoh Akihiko (00297293)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
22. Yang Yinjie (90808643)

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# of Collaborated Products: 10 results
23. 斉藤政樹 (60012762)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. 宮澤啓介 (50209897)

# of Collaborated Projects: 2 results

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25. NAGASHIMA Takahiro (10343443)

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26. MITSUMORI Toru (80377514)

# of Collaborated Projects: 1 results

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27. TAKAKU Tomoiku (20408256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Sato Eriko (60398675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. MIWA Akiyoshi (40200224)

# of Collaborated Projects: 1 results

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30. GUNJI Yuji (90245043)

# of Collaborated Projects: 1 results

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31. IIMURA Osamu (60265246)

# of Collaborated Projects: 1 results

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32. ANDO Yasuhiro (50212676)

# of Collaborated Projects: 1 results

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33. IWAMA Atsushi (70244126)

# of Collaborated Projects: 1 results

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34. AMEMIYA Youichi (10101338)

# of Collaborated Projects: 1 results

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35. SAKAMOTO Shinobu (70095016)

# of Collaborated Projects: 1 results

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36. MATSUOKA Shuji (20286743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. Takahashi Harumi (20211344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. MIZUKAMI Yoshihisa (30756698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
39. Masubuchi Nami (00791641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
40. 宮島篤 (50135232)

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# of Collaborated Products: 0 results
41. 吉村昭彦 (90182815)

# of Collaborated Projects: 1 results

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42. 田賀哲也 (40192629)

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43. 福永理己郎 (40189965)

# of Collaborated Projects: 1 results

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44. 金倉譲 (20177489)

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45. 横田崇 (50134622)

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46. 倉田寛一 (90215038)

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47. 角田純一 (20245054)

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48. 永井正 (40237483)

# of Collaborated Projects: 1 results

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49. 河合純 (30391923)

# of Collaborated Projects: 1 results

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50. 堂前直 (00321787)

# of Collaborated Projects: 1 results

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51. 久野敦 (50302287)

# of Collaborated Projects: 1 results

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52. ABE Masaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
53. TOYOTA Tokuko

# of Collaborated Projects: 1 results

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54. ITO akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
55. SHIDE Kotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. SAITO Shinya

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57. 松井崇

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# of Collaborated Products: 1 results
58. 横山武司

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# of Collaborated Products: 1 results
59. 森谷昇太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 織谷健司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 合山進

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# of Collaborated Products: 1 results
62. 平本正樹

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# of Collaborated Products: 1 results
63. 下妻晃二郎

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# of Collaborated Products: 1 results

KOMATSU Norio 小松 則夫

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Understanding the mechanism of cell tumorigenesis promoted by essential thrombocythemia specific transcriptional networkPrincipal Investigator

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Clarification of the pathogenesis of myeloproliferative neoplasms based on the identification of genetic factors in familial casesPrincipal Investigator

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KOMATSU Norio 小松則夫