Saito Yoshiro 斎藤嘉朗

… Alternative Names

SAITO Yoshiro 斎藤嘉朗

齋藤嘉朗サイトウヨシロウ

斎藤嘉朗サイトウヨシロウ

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Researcher Number	50215571
Other IDs
Affiliation (Current)	2025: 国立医薬品食品衛生研究所, その他部局等, 所長
Affiliation (based on the past Project Information) *help	2023: 国立医薬品食品衛生研究所, その他部局等, 副所長 2009 – 2022: 国立医薬品食品衛生研究所, 医薬安全科学部, 部長 2010 – 2011: National Institute of Health Sciences, 研究員 2009: National Institute of Health Sciences, 医薬安全科学部, 室長 2005 – 2008: 国立医薬品食品衛生研究所, 機能生化学部, 室長 … More 2001: 国立医薬品食品衛生研究所, 機能生化学部, 室長 2000: 国立医薬品食品衛生研究所, 機能生化学部, 主任研究官 1995 – 1996: 国立衛生試験所, 機能生化学部, 研究員 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Applied pharmacology / Biological pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 49010:Pathological biochemistry-related / Basic Section 47060:Clinical pharmacy-related / Ophthalmology / Applied pharmacology / Physical pharmacy / Medical pharmacy
Keywords	Principal Investigator 副作用 / ゲノム / 薬剤反応性 / トランスレーショナルリサーチ / 抗がん剤 / 薬理学 / 調節機構 / ヒト成長ホルモン結合蛋白 / ヒト成長ホルモン / 薬物性肝障害 … More / HLA / 機序 / Genome / Gene / Pharmacology / Drug response / 安定性 / 薬物代謝酵素 / 薬剤反応 / 遺伝子 / バイオマーカー / ファーマコゲノミクス / 医薬品副作用 / 抗体医薬品 / グノム / 転写因子 / 薬物トランスポーター / OBCAM / プリオン / GPIアンカー型糖蛋白質 / 折りたたみ / シャペロン / 小胞体 / 蛋白質リン酸化反応 / 生成機構 … More Except Principal Investigator 遺伝子多型 / 血液検査 / バイオマーカー / 間質性肺炎 / Stratifin / 肺胞上皮細胞 / 薬剤性間質性肺炎 / DAD / びまん性肺胞傷害 / 遺伝子診断薬 / 抗てんかん薬 / 重症薬疹 / 眼表面炎症 / 脂質 / メタボロミクス / 脂質メディエーター / 眼表面炎症性疾患 / 酵素 / 生理活性 / 癌 / 酸化還元酵素 / 量子ビーム / 薬物代謝酵素 / 構造生物学 / 遺伝子 / 抗がん剤 / 薬理学 / 臨床 / ゲノム / ハプロタイプ / 薬剤反応性 / α-1-酸性糖蛋白 / オーダーメード医療 Less

抗てんかん薬による重症薬疹発症予測のための遺伝子診断薬の開発
- Principal Investigator
  
  塚越絵里
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Institute of Health Sciences
The elucidation of expression mechanism and biological functions of a novel biomarker for diffuse alveolar damage
- Principal Investigator
  
  荒川憲昭
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  National Institute of Health Sciences
Research on genomic biomarker exploration on drug-induced liver injury in Japanese, their functional analysis and diagnosisPrincipal Investigator
- Principal Investigator
  
  Saito Yoshiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Institute of Health Sciences
Construction of novel MHC-class II based strategy and evaluation method for drug-induced myopathy.Principal Investigator
- Principal Investigator
  
  Saito Yoshiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
Development of a diagnostic method for severe cutaneous adverse reactions by genom biomarkers and their pathophysiological relevanceicPrincipal Investigator
- Principal Investigator
  
  Saito Yoshiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Analysis of Pathogenesis and disease marker of ocular surface inflammatory diseases using lipid metabolomics
- Principal Investigator
  
  KINOSHITA SHIGERU
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation on pathophysiological significance of orphan P450 expression in tumor tissue and its application to drug discovery research
- Principal Investigator
  
  Maekawa Keiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Reverse omics analysis for mechanisms on hand-foot syndrome and predictive system construction.Principal Investigator
- Principal Investigator
  
  SAITO Yoshiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
Mechanistic analysis and prediction of infusion reactionsPrincipal Investigator
- Principal Investigator
  
  SAITO Yoshiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Structure‐activity relationship studies of CYP2C9 genetic variants
- Principal Investigator
  
  MAEKAWA Keiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Health Sciences
Association of genotypes for drug-binding protein with anti-cancer drug responses
- Principal Investigator
  
  SAI Kimie
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明Principal Investigator
- Principal Investigator
  
  斎藤嘉朗
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Effects of genetic polymorphisms in 3'-untranslated region on the expression and function of drug metabolizing enzymes.Principal Investigator
- Principal Investigator
  
  YOSHIRO Saito
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
GPI-アンカー型糖蛋白質の品質管理における小胞体シャペロンの役割Principal Investigator
- Principal Investigator
  
  斎藤嘉朗
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
ヒト成長ホルモン結合蛋白の生成に関与するプロテアーゼに関する研究Principal Investigator
- Principal Investigator
  
  斎藤嘉朗
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  国立衛生試験所
ヒト成長ホルモン結合蛋白の生成及びその調節に関する研究Principal Investigator
- Principal Investigator
  
  斎藤嘉朗
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  国立衛生試験所

[Book] バイオ医薬品（26章　テーラーメイドゲノム創薬）2013
- Author(s)
  斎藤嘉朗, 中野泰子
- Total Pages
  8
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23390144
[Book] バイオ医薬品(26章テーラーメイドゲノム創薬)2013
- Author(s)
  斎藤嘉朗, 中野泰子
- Total Pages
  8
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 20232024
- Author(s)
  Tsukagoshi E, Nakamura R, Kaniwa N, Sai K, Kikura-Hanajiri R, Matsunaga K, Abe R, Asada H, Saito Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 1 Pages: 88-97
- DOI
  10.1248/bpb.b23-00595
- ISSN
  0918-6158, 1347-5215
- URL
  https://localhost/en/publications/defd3f49-a572-4a47-9f7e-cb00af1e832e
- Year and Date
  2024-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06760, KAKENHI-PROJECT-21K08306
[Journal Article] Differential Effects of HLA-B8727;15:11 and HLA-A8727;31:01 on Carbamazepine-Induced Cutaneous Adverse Reactions.2023
- Author(s)
  Fukunaga K, Tsukagoshi E, Kurata M, Mizukawa Y, Niihara H, Morita E, Watanabe Y, Yamaguchi Y, Watanabe H, Nakajima S, Nomura T, Kabashima K, Tohyama M, Azukizawa H, Asada H, Hasegawa A, Hama N, Ozeki T, Mashimo Y, Sekine A, Matsunaga K, Tanaka Y, Nakamura R, Abe R, Mushiroda T, Saito Y.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 144（４） Issue: 4 Pages: 908-911
- DOI
  10.1016/j.jid.2023.09.282
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16222, KAKENHI-PROJECT-22K05978, KAKENHI-PROJECT-22K06760, KAKENHI-PROJECT-21K08306
[Journal Article] 薬物性肝障害発症に関連するバイオマーカー2022
- Author(s)
  中村亮介、荒川憲昭、斎藤嘉朗
- Journal Title
  
  医学のあゆみ
  
  Volume: 280 Pages: 1286-1291
- Data Source
  KAKENHI-PROJECT-18K06775
[Journal Article] 精神科関連医薬品の副作用バイオマーカー2020
- Author(s)
  田中庸一，塚越絵里，斎藤嘉朗
- Journal Title
  
  精神科
  
  Volume: 37 Pages: 634-641
- Data Source
  KAKENHI-PROJECT-18K06775
[Journal Article] ゲノム情報に基づいた副作用予測2019
- Author(s)
  斎藤嘉朗, 青木良子, 荒川憲昭
- Journal Title
  
  日本臨牀
  
  Volume: 77 Pages: 18-24
- Data Source
  KAKENHI-PROJECT-18K06775
[Journal Article] Conference report: pharmacogenomics in special populations at WCP20182019
- Author(s)
  Suarez‐Kurtz Guilherme、Aklillu Eleni、Saito Yoshiro、Somogyi Andrew A.
- Journal Title
  
  British Journal of Clinical Pharmacology
  
  Volume: 85 Issue: 3 Pages: 467-475
- DOI
  10.1111/bcp.13828
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06775, KAKENHI-PROJECT-15K15009
[Journal Article] Pharmacogenomic information in the Warning section of drug labels: A comparison between labels in the United States and those in five other countries/regions.2018
- Author(s)
  Imatoh T, Sai K, Saito Y
- Journal Title
  
  J Clin Pharm Ther.
  
  Volume: 43 Issue: 4 Pages: 493-499
- DOI
  10.1111/jcpt.12691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293122, KAKENHI-PROJECT-18K06775, KAKENHI-PROJECT-15K15009
[Journal Article] Pharmacogenomic information in the Warning section of drug labels: A comparison between labels in the United States and those in five other countries/regions.2018
- Author(s)
  Imatoh T, Sai K, Saito Y
- Journal Title
  
  J Clin Pharm Ther.
  
  Volume: 43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15009
[Journal Article] Diurnal glycemic fluctuation is associated with severity of coronary artery disease in prediabetic patients: Possible role of nitrotyrosine and glyceraldehyde-derived advanced glycation end products2017
- Author(s)
  Watanabe M. Kawai Y, Kitayama M, Akao H, Motoyama A, Wakasa M, Saito R, Aoki H, Fujibayashi K, Tsuchiya T, Nakanishi H, Saito K, Takeuchi M, Kajinami K.
- Journal Title
  
  Journal of Cardiology
  
  Volume: 69 Issue: 6 Pages: 625-631
- DOI
  10.1016/j.dmpk.2016.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09105, KAKENHI-PROJECT-15K15009
[Journal Article] Clinical pharmacogenetics implementation consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update.2016
- Author(s)
  Saito Y, Stamp LK, Caudle KE, Hershfield M, McDonagh EM, Callagham JT, Tassaneeyakul W, Mushiroda T, Kamatani N, Goldspiel BR, Phillips EJ, Klein TE, Lee MTM
- Journal Title
  
  Clin. Pharmacol. Ther.
  
  Volume: 99 Issue: 1 Pages: 36-37
- DOI
  10.1002/cpt.161
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293122
[Journal Article] Crystal structure analysis of human drug metabolizing enzyme CYP2C9 complexed with medicinal compound Losartan.2016
- Author(s)
  Adachi M, Matsuzawa Y, Kuroki R, Saito Y and Maekawa K
- Journal Title
  
  Photon Factory Activity Report
  
  Volume: 33 Pages: 364-364
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293128
[Journal Article] Cross-Classification of Human Urinary Lipidome by Sex, Age, and Body Mass Index.2016
- Author(s)
  Okemoto K, Maekawa K, Tajima Y, Tohkin M, Saito Y
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: e0168188-e0168188
- DOI
  10.1371/journal.pone.0168188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293128
[Journal Article] Plasma Lipid Profiling of Patients with Chronic Ocular Complications Caused by Stevens Johnson Syndrome/Toxic Epidermal Necrolysis2016
- Author(s)
  Saito K, Ueta M, Maekawa K, Sotozono C, Kinoshita S, Saito Y
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 11 Pages: e0167402-e0167402
- DOI
  10.1371/journal.pone.0167402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05488, KAKENHI-PROJECT-26293122, KAKENHI-PROJECT-16K11327
[Journal Article] 臨床における重症薬疹とゲノムマーカー.2015
- Author(s)
  岡本（内田）好海, 児玉進, 中村亮介, 斎藤嘉朗
- Journal Title
  
  毒性質問箱
  
  Volume: 17 Pages: 18-23
- Data Source
  KAKENHI-PROJECT-15K15009
[Journal Article] Drugs causing severe ocular surface involvements in Japanese patients with StevenseJohnson syndrome/toxic epidermal necrolysis2015
- Author(s)
  Kaniwa N, Ueta M, Nakamura R, Okamoto-Uchida Y, Sugiyama E, Maekawa K, Takahashi Y, Furuya H, Yagami A, Matsukura S, Ikezawa Z, Matsunaga K, Sotozono C, Aihara M, Kinoshita S, Saito Y.
- Journal Title
  
  Allergol. Int.
  
  Volume: 64 Issue: 4 Pages: 379-381
- DOI
  10.1016/j.alit.2015.05.002
- NAID
  130005290406
- ISSN
  1323-8930, 1440-1592
- URL
  https://pure.teikyo.jp/en/publications/a7a49a0d-8ee1-4d6b-a63c-785d9c902fc7
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460082, KAKENHI-PROJECT-25293355, KAKENHI-PROJECT-26293122, KAKENHI-PROJECT-15K19168
[Journal Article] Predictive Genomic Markers for Severe Adverse Drug Reactions2015
- Author(s)
  Saito Y, Kodama S, Sugiyama E, Nakamura R.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 135 Issue: 4 Pages: 589-595
- DOI
  10.1248/yakushi.14-00249-3
- NAID
  130005060821
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2015-04-01
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659078, KAKENHI-PROJECT-26293122
[Journal Article] 副作用バイオマーカーの探索と臨床応用研究の現状について2013
- Author(s)
  斎藤嘉朗, 中村亮介, 黒瀬光一
- Journal Title
  
  臨床病理レビュー
  
  Volume: 150 Pages: 27-33
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Biomarker Exploration and Its Clinical Use2013
- Author(s)
  Saito Y, Sai K, Kaniwa N, Tajima Y, Ishikawa M, Nishimaki-Mogami T, Maekawa K.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 133 Issue: 12 Pages: 1373-1379
- DOI
  10.1248/yakushi.13-00232-2
- NAID
  130003382293
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2013-12-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390144, KAKENHI-PROJECT-24659078
[Journal Article] バイオマーカー探索研究とその臨床応用に向けて2013
- Author(s)
  斎藤嘉朗, 佐井君江, 鹿庭なほ子, 田島陽子, 石川将己, 最上(西巻)知子, 前川京子
- Journal Title
  
  薬学雑誌
  
  Volume: 133 Pages: 1373-1379
- NAID
  130003382293
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] 市販後安全性確保に係るバイオマーカーと診断2013
- Author(s)
  斎藤嘉朗, 前川京子, 田島陽子, 児玉進, 黒瀬光一
- Journal Title
  
  レギュラトリーサイエンス学会誌
  
  Volume: 3 Pages: 43-55
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] 本邦の医薬品添付文書におけるゲノム薬理学関連情報およびその検査法の状況に関する調査・解析2012
- Author(s)
  門脇京子, 石黒昭博, 高松昭司, 斎藤嘉朗, 宇山佳明
- Journal Title
  
  レギュラトリーサイエンス学会誌
  
  Volume: 2 Pages: 83-92
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant2012
- Author(s)
  Tada M, Ishii-Watabe A, Maekawa K, Fukushima-Uesaka H, Kurose K, Suzuki T, Kaniwa N, Sawada J, Kawasaki N, Nakajima TE, Kato K, Yamada Y, Shimada Y, Yoshida T, Ura T, Saito M, Muro K, Doi T, Fuse N, Yoshino T, Ohtsu A, Saijo N, Okuda H, Hamaguchi T, Saito Y, Matsumura Y
- Journal Title
  
  Immunogenetics
  
  Volume: 64 Pages: 869-877
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] 日本人を対象にしたゲノム・メタボローム解析によるバイオマーカー探索2012
- Author(s)
  斎藤　嘉朗、他
- Journal Title
  
  Pharmstage
  
  Volume: 2012.9 Pages: 1-4
- NAID
  40019436709
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] 日本人を対象にしたゲノム・メタボローム解析によるバイオマーカー探索2012
- Author(s)
  斎藤嘉朗, 前川京子, 鹿庭なほ子
- Journal Title
  
  Pharmstage
  
  Volume: 9 Pages: 1-4
- NAID
  40019436709
- Data Source
  KAKENHI-PROJECT-23390144
[Journal Article] Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients2011
- Author(s)
  Katori N, Sai K, Saito Y, Fukushima-Uesaka H, Kurose K,(fifteen other co-authors)
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 100 Pages: 4546-4559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590191
[Journal Article] Genetic Polymorphisms and Haplotypes of Major Drug Metabolizing Enzymes in East Asians and Their Comparison with Other Ethnic Populations.2007
- Author(s)
  Saito Y, Maekawa K, Ozawa S, Sawada J.
- Journal Title
  
  Current Pharmacogenomics vol.5, no.1
  
  Pages: 49-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] A Combinatorial Haplotype of the UDP-Glucuronosyltransferase 1A1 Gene (^#60-^#IB) Increases Total Bilirubin Concentrations in Japanese Voluteers.2007
- Author(s)
  Saeki M, Saito Y, Sai K, Maekawa K, Kaniwa N, Sawada J, Kawamoto M, Saito A, Kamatani N.
- Journal Title
  
  Clinical Chemistry 53(2)
  
  Pages: 356-358
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] Genetic Polymorphisms and Haplotypes of Major Drug Metabolizing Enzymes in East Asians and Their Comparison with Other Ethnic Populations.2007
- Author(s)
  Saito Y, Maekawa K, Ozawa S, Sawada J.
- Journal Title
  
  Current Pharmacogenomics 5(1)
  
  Pages: 49-78
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] A Combinatorial Haplotype of the UDP-Glucuronosyltransferase 1A1 Gene(^#60-^#IB) Increases Total Bilirubin Concentrations in Japanese Volunteers.2007
- Author(s)
  Saeki M, Saito Y, Sai K, Maekawa K, Kaniwa N, Sawada J, Kawamoto M, Saito A, Kamatani N.
- Journal Title
  
  Clinical Chemistry 53(2)
  
  Pages: 356-358
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] A Combinatorial Haplotype of the UDP-Glucuronosyltransferase 1A1 Gene(#60#IB) Increases Total Bilirubin Concentrations in Japanese Volunteers.2007
- Author(s)
  Saeki M, Saito Y, Sai K, Maekawa K, Kaniwa N, Sawada J, Kawamoto M, Saito A, Kamatani N.
- Journal Title
  
  Clinical Chemistry vol.53, no, 2
  
  Pages: 356-358
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] Genetic Polymorphisms and Haplotypes of Major Drug Metabolizing Enzymes in East Asians and Their Comparison with Other Ethnic Populations.2007
- Author(s)
  Saito Y, Maekawa K, Ozawa S, Sawada J.
- Journal Title
  
  Current Pjharmacogenomics 5(1)
  
  Pages: 49-78
- Data Source
  KAKENHI-PROJECT-17590142
[Journal Article] 本邦の医薬品添付文書におけるゲノム薬理学関連情報およびその検査法の状況に関する調査・解析
- Author(s)
  門脇京子、石黒昭博、高松昭司、斎藤嘉朗、宇山佳明
- Journal Title
  
  レギュラトリーサイエンス学会誌
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] Stevens-Johnson症候群および中毒性表皮壊死融解症（SJS/TEN）の全国症例集積ネットワークを用いた患者の臨床的特徴の解析2023
- Author(s)
  塚越絵里, 中村亮介, 鹿庭なほ子, 佐井君江, 松永佳世子, 阿部理一郎, 浅田秀夫, 斎藤嘉朗, 花尻（木倉）瑠理
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] Validation of a novel genotyping technique for a surrogate marker of HLA-B*58:01 to predict allopurinol-induced SJS/TEN in Japanese.2023
- Author(s)
  Tsukagoshi E, Nakamura R, Asada H, Saito Y
- Organizer
  第30回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] 医薬品による重症薬疹の発症機序と発現予測2022
- Author(s)
  斎藤嘉朗，荒川憲昭、塚越絵里，中村亮介
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] 日本人におけるスルホンアミド系薬剤による重症薬疹の発症とHLA-A*11:01の関連2022
- Author(s)
  中村亮介, 大関健志, 平山令明, 関根章博, 水川良子, 塩原哲夫, 渡辺秀晃, 末木博彦, 小川浩平, 浅田秀夫, 塚越絵里, 松永佳世子, 新原寛之, 山口由衣, 相原道子, 莚田泰誠, 斎藤嘉朗, 森田栄伸
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] 日本人におけるサルファ剤による重症薬疹の発症とHLA-A*11:01の関連2022
- Author(s)
  中村亮介, 大関健志, 平山令明, 関根章博, 水川良子, 塩原哲夫, 渡辺秀晃, 末木博彦, 小川浩平, 浅田秀夫, 塚越絵里, 松永佳世子, 新原寛之, 山口由衣, 相原道子, 莚田泰誠, 斎藤嘉朗, 森田栄伸
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] アロプリノールによるSJS/TEN発症に関連する一塩基多型を用いた遺伝子診断の分析法バリデーション2022
- Author(s)
  塚越絵里，中村亮介，浅田秀夫，斎藤嘉朗
- Organizer
  第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] Development of a method for genotyping a surrogate marker of HLA-B*58:01 for allopurinol-induced SJS/TEN.2022
- Author(s)
  Tsukagoshi E, Nakamura R, Asada H, Saito Y
- Organizer
  第29回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-22K06760
[Presentation] 日本人における薬物肝障害バイオマーカー候補の検証2019
- Author(s)
  荒川憲昭, 斎藤嘉朗
- Organizer
  第40回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06775
[Presentation] バイオマーカーの適格性確認に関する国際規制動向と日本の取り組み2019
- Author(s)
  斎藤嘉朗
- Organizer
  第40回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06775
[Presentation] Pharmacogenomic research and its implementation in Asian region2018
- Author(s)
  Saito Y
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] 非げっ歯類ゲノム解析への臨床からの期待2018
- Author(s)
  斎藤嘉朗、中村亮介
- Organizer
  第45回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06775
[Presentation] Pharmacogenomic research and its implementation in Asian region2018
- Author(s)
  Saito Y
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06775
[Presentation] 副作用回避へのバイオマーカー情報の応用と課題2017
- Author(s)
  斎藤嘉朗
- Organizer
  第55回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] オミックス解析による副作用バイオマーカー開発の進展2017
- Author(s)
  斎藤嘉朗
- Organizer
  第38回日本臨床薬理学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Introduction to the skin as a target for immune-mediated drug hypersensitivity2017
- Author(s)
  Yoshiro Saito
- Organizer
  Society of Toxicology, 56th Annual Meeting and ToxExpo
- Place of Presentation
  USA, Baltimore
- Year and Date
  2017-03-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Genomic biomarkers and patients’ background information for onset of SJS/TEN2017
- Author(s)
  Yoshiro Saito, Ryosuke Nakamura
- Organizer
  2nd International Stevens-Johnson Syndrome Symposium
- Place of Presentation
  Kyoto
- Year and Date
  2017-01-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] オミックス解析による副作用バイオマーカー開発の進展2017
- Author(s)
  斎藤嘉朗
- Organizer
  第38回日本臨床薬理学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] 副作用回避へのバイオマーカー情報の応用と課題2017
- Author(s)
  斎藤嘉朗
- Organizer
  第55回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Use of PGx information for prediction of severe adverse drug reactions: Current status and future perspectives2016
- Author(s)
  Yoshiro Saito, Keiko Maekawa, Ryosuke Nakamura
- Organizer
  第14回日本臨床腫瘍学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] 医薬品適正使用のためのバイオマーカーおよび薬剤疫学的情報の活用2016
- Author(s)
  斎藤嘉朗
- Organizer
  第66回日本薬学会近畿支部大会
- Place of Presentation
  大阪
- Year and Date
  2016-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] 副作用予測のためのゲノムバイオマーカー探索とそのin vitro 評価2016
- Author(s)
  斎藤嘉朗、前川京子、中村亮介
- Organizer
  第29回　日本動物実験代替法学会
- Place of Presentation
  福岡
- Year and Date
  2016-11-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] バイオマーカー開発の現状と課題2016
- Author(s)
  斎藤嘉朗
- Organizer
  第6回レギュラトリーサイエンス学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Crystal Structures of CYP2C9, CYP2C9*3 and CYP2C9*30 in Complex with Multiple Losartan Molecules Reveal a Peripheral Binding Site and Alternate Active Site Orientations.2016
- Author(s)
  Maekawa K, Adachi M, Matsuzawa Y, Kuroki R, Saito Y, Shah M
- Organizer
  The 21st International Symposium on Microsomes and Drug Oxidations (MDO2016)
- Place of Presentation
  UC Davis Conference Center, Davis, California, USA
- Year and Date
  2016-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] Orphan P450 expression and oxidative fatty acid metabolite levels in breast cancer2016
- Author(s)
  Keiko Maekawa, Yumiko Matsuzawa,　Yoshiro Saito, Shin-ichi Yachida
- Organizer
  日本薬理学会８９回年会
- Place of Presentation
  パシフッコ横浜
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] Genomic markers associated with Stevens-Johnson syndrome/epidermal necrolysis in Japan; A JSAR group study.2016
- Author(s)
  Saito Y and Nakamura R
- Organizer
  1st International Stevens-Johnson Syndrome Symposium
- Place of Presentation
  京都
- Year and Date
  2016-01-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Prediction of severe adverse drug reactions using pharmacogenomic biomarkers: Current status and future prospects in Japan2016
- Author(s)
  Yoshiro Saito, Keiko Maekawa and Ryosuke Nakamura
- Organizer
  International Conference on Human Genetics
- Place of Presentation
  Kyoto
- Year and Date
  2016-04-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] Biomarker regulation and regulatory sciences in Japan2016
- Author(s)
  Yoshiro Saito
- Organizer
  11th International ISSX meeting
- Place of Presentation
  韓国　釜山
- Year and Date
  2016-06-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] 重症眼粘膜障害を伴うSJS/TENの発症と関連する被疑薬およびHLA型について.2015
- Author(s)
  中村亮介, 鹿庭なほ子, 上田真由美, 岡本(内田)好海, 杉山永見子, 高橋幸利, 古谷博和, 矢上晶子, 松倉節子, 池澤善郎, 松永佳世子, 徳永勝士, 外園千恵, 相原道子, 木下茂, 斎藤嘉朗
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] ゲノム薬理学とTDMへの応用2015
- Author(s)
  斎藤嘉朗
- Organizer
  第32回日本TDM学会学術大会
- Place of Presentation
  松本
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] ヒト由来薬物代謝酵素CYP2C9の一塩基置換体(*3および*30)と抗高血圧薬ロサルタンとの複合体のＸ線結晶構造解析2015
- Author(s)
  安達基泰, 黒木良太、前川京子, 松澤由美子, 斎藤嘉朗
- Organizer
  BMB2015（第 38回日本分子生物学会年会、第 88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] 国内の動向：臨床試料を用いた安全性バイオマーカー探索と検証 ―セーフティートランスレーションにおける課題―.2015
- Author(s)
  斎藤嘉朗, 前川京子, 齊藤公亮, 中村亮介, 熊谷雄治
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] 日本人におけるスタチン誘因性筋障害発症と関連するHLA遺伝子型2015
- Author(s)
  佐井君江，梶波康二，赤尾浩慶，今任拓也，松澤由美子，前川京子，日本 PGxデータサイエンスコソーシアム，斎藤嘉朗
- Organizer
  第22回日本免疫毒性学会学術年会
- Place of Presentation
  京都
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] Genetic background of stain-related myopathy in Japanese2015
- Author(s)
  Kajinami K, Akao H, Sai K, Maekawa K, Japanese Pharmacogenomics Data Science Consortium, Saito Y
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-26
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] Purification of cytochrome P450 2C9.1, 2C9.3 and 2C9.30 expressed in E. coli and their activities toward arachidonic acid in vitro2015
- Author(s)
  Keiko Maekawa, Yumiko Matsuzawa, Motoyasu Adachi, Ryota Kuroki, Yoshiro Saito
- Organizer
  19th International Conference on Cytochrome P450
- Place of Presentation
  National Olympics Memorial Youth Center, Shibuya-ku, Tokyo
- Year and Date
  2015-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] 国内の動向：臨床試料を用いた安全性バイオマーカー探索と検証2015
- Author(s)
  斎藤嘉朗, 前川京子, 齊藤公亮, 中村亮介, 熊谷雄治
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K15009
[Presentation] 重篤副作用に関する予測ゲノムマーカー2014
- Author(s)
  斎藤嘉朗, 児玉進, 杉山永見子, 中村亮介
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] 抗体医薬を含むバイオ医薬品の薬物動態, 薬物間相互作用2014
- Author(s)
  斎藤嘉朗
- Organizer
  日本薬物動態学会第28回ワークショップ
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] 抗体医薬を含むバイオ医薬品の薬物動態、薬物間相互作用2014
- Author(s)
  斎藤嘉朗
- Organizer
  日本薬物動態学会　第28回ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] 重篤副作用に関する予測ゲノムマーカー2014
- Author(s)
  斎藤嘉朗, 児玉進, 杉山永見子, 中村亮介
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] 重篤副作用におけるGWAS解析2013
- Author(s)
  斎藤嘉朗，頭金正博, 中村亮介, 関根章博, 鹿庭なほ子
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] バイオマーカー探索研究とその臨床応用に向けての課題2013
- Author(s)
  斎藤　嘉朗、他
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] 重篤副作用におけるGWAS解析2013
- Author(s)
  斎藤嘉朗, 頭金正博, 中村亮介, 関根章博, 鹿庭なほ子
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] ゲノミクスおよびメタボロミクス解析によるバイオマーカー探索2013
- Author(s)
  斎藤嘉朗，鹿庭なほ子，佐井君江，花谷忠昭，中村亮介，前川京子
- Organizer
  第16回日本医薬品情報学会総会・学術大会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] ヒト試料を用いたバイオマーカー研究の現状と問題点2012
- Author(s)
  斎藤　嘉朗、他
- Organizer
  第33 回日本臨床薬理学会学術総会
- Place of Presentation
  沖縄県宜野湾市
- Invited
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] バイオ医薬品と化学合成医薬品の相互作用2012
- Author(s)
  斎藤嘉朗, 佐井君江, 石井明子
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] バイオ医薬品と化学合成医薬品の相互作用2012
- Author(s)
  斎藤　嘉朗、他
- Organizer
  日本薬物動態学会第27 回年会
- Place of Presentation
  東京都江戸川区
- Invited
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] ヒト試料を用いたバイオマーカー研究の現状と問題点2012
- Author(s)
  斎藤嘉朗, 前川京子, 佐井君江, 鹿庭なほ子, 黒瀬光一
- Organizer
  第33回日本臨床薬理学会学術総会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23390144
[Presentation] 臨床的に重要な副作用のゲノム解析に関する取り組みの現況と今後のメタボロミクス解析の必要性等について2012
- Author(s)
  斎藤　嘉朗、他
- Organizer
  第39 回日本毒性学会学術年会
- Place of Presentation
  仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] パクリタキセル投与患者におけるα1-acid glycoproteinと遺伝子多型、薬物動態および患者背景因子の関連性2011
- Author(s)
  香取典子、佐井君江、斎藤嘉朗, 他14名
- Organizer
  日本薬学会第131年回
- Place of Presentation
  ツインメッセ静岡(静岡)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] パクリタキセル投与患者におけるα-1-acid glycoproteinと遺伝子多型、薬物動態および患者背景因子の関連性2011
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一(他12名)
- Organizer
  日本薬学会第131年回
- Place of Presentation
  ツインメッセ静岡(静岡)
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Effects of CYP2C9*3, *28 and *30 on CYP2C9 Inhibition profiles and Glyburide metabolism in Vitro2011
- Author(s)
  Keiko Maekawa, Noriko Harakawa, Su-Ryang Kim, Jun-ichi Sawada, Yoshiro Saito
- Organizer
  第17回北米薬物動態学会
- Place of Presentation
  アトランタアメリカ合衆国
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22590054
[Presentation] Effects of CYP2C9*3, *28 and *30 on CYP2C9 Inhibition profiles and Glyburide metabolism in Vitro2011
- Author(s)
  Maekawa K, Harakawa N, Kim SR, Sawada J, Saito Y
- Organizer
  第17回北米薬物動態学会
- Place of Presentation
  アトランタアメリカ合衆国
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22590054
[Presentation] 日本人癌患者のORM遺伝子多型による血中α-1-酸性糖蛋白レベルへの影響2010
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一、(他12名)
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] 日本人癌患者のORM遺伝子多型による血中α1酸性糖蛋白レベルへの影響2010
- Author(s)
  香取典子、佐井君江、斎藤嘉朗, 他14名
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Genetic polymorphisms of ORM1 and ORM2 genes encoding al-acid glycoproteins in a Japanese population2009
- Author(s)
  香取典子、斎藤嘉朗、佐井君江, (他15名)
- Organizer
  第16回ISSX北米大会
- Place of Presentation
  ボルチモアマリオット(ボルチモア、米国)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Haplotype structure of genes encoding α1-acid glycoprotein in a Japanese population2009
- Author(s)
  香取典子、斎藤嘉朗、佐井君江, (他15名)
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] スルホニルウレア受容体SUR2をコードするABCC9遺伝子の多型探索およびハプロタイプ解析2008
- Author(s)
  斎藤嘉朗
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590554
[Presentation] Involvement of a Combinatorial UDP-Glucuronosyltransferase 1A1 Haplotype(#60#IB) in Increases of Total Bilirubin Concentrations.2007
- Author(s)
  Saito Y, Saeki M, Sai K, Maekawa K, Kaniwa N, Sawada J, Kawamoto M, Saito A, Kamatani N.
- Organizer
  The 52nd Annual Meetin of the Japan Society of Human Genetics.
- Place of Presentation
  Tokyo
- Year and Date
  2007-09-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590142
[Presentation] 血清総ビリルビン値上昇へのUGT1A1ハプロタイプ・コンビネーション(#60-#IB)の関与2007
- Author(s)
  斎藤嘉朗、佐伯真弓、佐井君江、前川京子、鹿庭なほ子、澤田純一、川本学、斎藤聡、鎌谷直之
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-17590142
[Presentation] 血清総ビリルビン値上昇へのUGT1A1ハプロタイプ・コンビネーション(^#60-^#IB)の関与2007
- Author(s)
  齋藤嘉朗、佐伯真弓、佐井君江、前川京子、鹿庭なほ子、澤田純一、川本学、斎藤聡、鎌谷直之
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2007-09-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590142
[Presentation] Medication tendencies for inducing severe ocular surface symptoms in Japanese Stevens-Johnson syndrome / toxic epidermal necrolysis patients.
- Author(s)
  Saito Y, Ueta M, Nakamura R, Sugiyama E, Maekawa K, Takahashi Y, Furuya H, Yagami A, Matsukura S, Ikezawa Z, Matsunaga K, Sotozono C, Aihara M, Kinoshita S, Kaniwa N
- Organizer
  EAACI Drug Hypersensitivity Meeting, DHM 2014
- Place of Presentation
  Bern, Switzerland
- Year and Date
  2014-04-09 – 2014-04-12
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] リピドミクス解析による手足症候群関連代謝物候補のin vitro 探索．
- Author(s)
  斎藤嘉朗，松澤由美子，嶽本和久，石川将己，齊藤公亮，細井寛子，近藤俊輔，上野秀樹，奥坂拓志，前川京子
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] HLA association with antipyretic analgesics-induced Stevens-Johnson syndrome / toxic epidermal necrolysis with severe ocular surface complications in Japanese patients.
- Author(s)
  Nakamura R, Kaniwa N, Ueta M, Sotozono C, Sugiyama E, Maekawa K, Yagami A, Matsukura S, Ikezawa Z, Matsunaga K, Tokunaga K, Aihara M, Kinoshita S, Saito Y
- Organizer
  EAACI Drug Hypersensitivity Meeting, DHM 2014
- Place of Presentation
  Bern, Switzerland
- Year and Date
  2014-04-09 – 2014-04-12
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] Ｘ線結晶回折法によるヒト由来薬物代謝酵素CYP2C9および一塩基置換体(*30)と抗高血圧薬ロサルタンの相互作用解析
- Author(s)
  安達基泰, 前川京子, 松澤由美子, 斎藤嘉朗, 黒木良太
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] バイオマーカー探索・検証のためのヒト血液中脂質代謝物レベルに関する網羅的検討
- Author(s)
  前川京子, 石川将己, 妹尾勇弥, 田島陽子, 齊藤公亮, 浦田政世, 村山真由子,熊谷雄治, 斎藤嘉朗
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] ヒト試料を用いたバイオマーカー開発のためのレギュラトリーサイエンス.
- Author(s)
  斎藤嘉朗，齊藤公亮，児玉進，熊谷雄治，前川京子
- Organizer
  第35回日本臨床薬理学会学術総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2014-12-04 – 2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-24659078
[Presentation] 動物モデルを用いた医薬品化合物によるリン脂質症の解析
- Author(s)
  前川　京子、齊藤　公亮、山田　弘、斎藤　嘉朗
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] Purification of cytochrome P450 2C9.1, 2C9.3 and 2C9.30 expressed in E. coli and their activities toward arachidonic acid in vitro
- Author(s)
  Keiko Maekawa, Yumiko Matsuzawa, Motoyasu Adachi, Ryota Kuroki and Yoshiro Saito
- Organizer
  19th International Conference on Cytochrome P450
- Place of Presentation
  Tokyo
- Year and Date
  2015-06-12 – 2015-06-15
- Data Source
  KAKENHI-PROJECT-25293128
[Presentation] 日本人におけるカルバマゼピン誘因性薬疹発症の危険因子HLA-A*31:01 のサロゲートマーカー多型を対象としたタイピング系の構築．
- Author(s)
  前川京子, 水澤精穂, 北本綾, 北本卓也, 中村亮介, 杉山永見子, 上田真由美, 外園千恵, 池田浩子, 矢上晶子, 松倉節子, 木下茂, 村松正明, 古谷博和, 高橋幸利, 松永佳世子, 相原道子, 関根章博, 日本PGX データサイエンスコンソーシアム, 斎藤嘉朗
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] ヒト試料を用いたバイオマーカー開発のためのレギュラトリーサイエンス.
- Author(s)
  斎藤嘉朗，齊藤公亮，児玉進，熊谷雄治，前川京子
- Organizer
  第35回日本臨床薬理学会学術総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2014-12-04 – 2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-26293122
[]
[]
[]
[]

1. MAEKAWA Keiko (70270626)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. NAKAMURA Ryosuke (50333357)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. SAI Kimie (20195960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. KUROSE Koichi (30280754)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. ADACHI Motoyasu (60293958)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 荒川憲昭 (60398394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. KATORI Noriko (60142121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. ISHII Akiko (50291117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KATO Ken (50501855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TADA Minoru (50506954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SUGIYAMA Emiko (40574695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KONDO Shunsuke (90546201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. KINOSHITA SHIGERU (30116024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. UETA Mayumi (60398386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 石田誠一 (10270505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 谷内田真一 (20359920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 関根章博 (30425631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 高橋幸利 (70262764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 相原道子 (90231753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. 児玉進 (20621460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 塚越絵里 (60615384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
22. 浅田秀夫 (60252681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
23. 花岡正幸 (20334899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 河合康幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 中西宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 藤林幸輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 濱菜摘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 外園千恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Yoshiro 斎藤 嘉朗

SAITO Yoshiro 斎藤 嘉朗

齋藤 嘉朗 サイトウ ヨシロウ

斎藤 嘉朗 サイトウ ヨシロウ

Research Projects

Research Products

Co-Researchers

抗てんかん薬による重症薬疹発症予測のための遺伝子診断薬の開発

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The elucidation of expression mechanism and biological functions of a novel biomarker for diffuse alveolar damage

Principal Investigator

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Review Section

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Research on genomic biomarker exploration on drug-induced liver injury in Japanese, their functional analysis and diagnosisPrincipal Investigator

Principal Investigator

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Review Section

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Construction of novel MHC-class II based strategy and evaluation method for drug-induced myopathy.Principal Investigator

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Development of a diagnostic method for severe cutaneous adverse reactions by genom biomarkers and their pathophysiological relevanceicPrincipal Investigator

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Analysis of Pathogenesis and disease marker of ocular surface inflammatory diseases using lipid metabolomics

Principal Investigator

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Elucidation on pathophysiological significance of orphan P450 expression in tumor tissue and its application to drug discovery research

Principal Investigator

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Reverse omics analysis for mechanisms on hand-foot syndrome and predictive system construction.Principal Investigator

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Mechanistic analysis and prediction of infusion reactionsPrincipal Investigator

Principal Investigator

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Structure‐activity relationship studies of CYP2C9 genetic variants

Principal Investigator

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Association of genotypes for drug-binding protein with anti-cancer drug responses

Principal Investigator

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マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明Principal Investigator

Principal Investigator

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Effects of genetic polymorphisms in 3'-untranslated region on the expression and function of drug metabolizing enzymes.Principal Investigator

Saito Yoshiro 斎藤嘉朗

SAITO Yoshiro 斎藤嘉朗

齋藤嘉朗サイトウヨシロウ

斎藤嘉朗サイトウヨシロウ

[Book] バイオ医薬品（26章　テーラーメイドゲノム創薬）2013

[Book] バイオ医薬品(26章テーラーメイドゲノム創薬)2013