mitani kinuko 三谷絹子

… Alternative Names

Mitani Kinuko 三谷絹子

MITANI Kinuko 三谷絹子

Less

Researcher Number	50251244
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 獨協医科大学, 医学部, 教授 2000 – 2011: 獨協医科大学, 医学部, 教授 1999: 東京大学, 医学部・付属病院, 助手 1997 – 1999: 東京大学, 医学部附属病院, 助手 1996 – 1999: University of Tokyo, Hospital, Internal Medicine, Assistant Professor, 医学部・附属病院, 助手 … More 1997: 東京大学, 医学部・付属病院, 助手 1996 – 1997: 東京大学, 医学部, 助手 1993 – 1995: University of Tokyo, 3rd Dept.of Internal Med., Assistant Pro., 医学部(病), 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Hematology / Biological Sciences / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Hematology / Basic Section 54010:Hematology and medical oncology-related / Cell biology / Molecular biology
Keywords	Principal Investigator MEN / 白血病 / 転写因子 / AML1 / MLL / TEL / t(11;19) / 骨髄異形成症候群 / EVI-1 / CtBP … More / 急性巨核芽球性白血病 / ノックインマウス / ES / トランスジェニックマウス / ノックアウトマウス / p53 / 転写伸長因子 / RNAポリメラーゼII伸長因子 / t(3;21) / TGFβ / RUNX1 / ヒストン脱アセチル化酵素阻害剤 / EVI1 / ERK / ドミナント・ネガティブ効果 / アポトーシス / ドミナント・ネガティブ / PTPRR / 慢性骨髄性白血病 / 遺伝子 / 癌 / 内科 / SKP2 / RUNX1-EVI1 / JNK / Smad3 / leukemia / ベンチジン / ALAS-E / Evi1 / EBPα / C / ETS / アイソフォーム / MOZ / アセチル化 / ヘモグロビン / 赤芽球 / GATA1 / レトロウイルス / 染色体転座 / リン酸化 / inv(12) / GM細胞 / Creリコンビナーゼ / コンディショナルマウス / Lck / コンディショナル / ノックイン / ノックアウト / 伸長因子 / 分子標的療法 / 発現制御 / 中心体 / CD41 / 骨髄異形成 / 血小板増多 / isoform / chromosomal abnormality / transcription factor / 12p13 / t(12;21) / PPO / UT-7 / 染色体異常 / conditional knock-out mice / TGBβ / ノックイン・マウス / モデルマウス / 胸腺 / Creリコンビネース / ノック・イン / 造血幹細胞腫瘍 / 胎生致死 / コンディショナルノックアウト / apoptosis / Evi-1 / キメラ型転写因子 / MEM / AP-1 activity / t(11 ; 19) / elongation factor / RNA polymerase II elongation factor / t(11;19)(q.23;P13.1) / AP-1活性 / レポーター・アッセイ / miRNA / MDS / 予後不良 / 全生存 / 定量PCR法 / Taqman法 / AML / miR-9 / glvcophorin A / β-グロビン / エリスロポエチン / UT-7/GM / MIR-9 / マウス / MIR9 / microRNA / キメラマウス / 血小板ペルオキシダーゼ / EPO / TER119 / 巨核球 / 赤血球 / β-globn / GATAl / GATA-1 / PU.1 / 胎仔肝造血 / ピストン脱アセチル化酵素 / 転写活性 / 分化抑制 / LG-3 / replating / がん抑制因子 / CDKN1A / ピストン脱アセチル化酵素阻害剤 / ETO / GATAL / β-major globin / IALAS-E / EB / ヒストン脱アチヤル化酵素阻害剤 / GFP / tai-to-tail / アンチセンス / DTX2 / RUNX1, RUNX1 / Lox-P配列 / mSin3A / 分化 / MEL細胞 / 12p13転座 / 32D細胞 / UT7 / STAT3 / inv(12)(p13q13) / T細胞 / LCK / Tリンパ球 / Annexin II / コブルストン・アッセイ / 造血幹細胞 / ストローマ細胞 / OP9 / AP‐1活性 / t(11;19)(q23;p13.1) / t(11; 19) (q23; P13.1) / EPI-1 / 前白血病 / t(3;21)(q26;q22) / 急性転化 … More Except Principal Investigator AML1 / 転写因子 / 慢性骨髄性白血病 / 白血病 / Cas / Evi-1 / transcription factor / 急性転化 / Notch / SH3 / chromosomal translocation / 染色体転座 / EVI-1キメラ遺伝子 / t(3;21)転座 / GATA-2 / p53遺伝子 / 癌抑制遺伝子 / AML1遺伝子 / リン酸化 / チロシンリン酸化 / CIZ / GATA2 / LTC-IC / アデノウイルス / Jagged1 / Smad3 / JNK / TGFβ / focal adhesion / 細胞接着 / インテグリン / phosphorylation / 細胞分化 / 遺伝子治療 / 分化抑制 / chimeric protein / EVI-1 / 転座型白血病 / EVi-1 / ALL / キメラ蛋白質 / AML-1 / AML1 gene / blastic crisis / 造血 / ES細胞 / RUNX1 / 造血幹細胞 / ノックアウトマウス / 細胞周期 / p16遺伝子 / EVI-1遺伝子 / MLL遺伝子 / チロシンキナーゼ / 遺伝性素因 / MDS / nucleo-cytoplasmic shuttling protein / actin stress fiber / matrix metalloproteinase / SH3 domain / 転写制御 / プロモーター / マトリックスメタロプロテアーゼ / 心筋線維 / アクチン / マトリックス・メタロプロテアーゼ / 細胞骨格 / differentiation inhibition / hematopoiesis / cleavage / signal / DSL蛋白質 / Notchリガンド / 分子抑制 / 分子内切断 / シグナル / colony-forming unit / long-term culture-initiating cell / CD34+cells / epidermal growth factor / adenovirus vector / hematopoietic stem cell / ex vivo expansion / SCF / インターロイキン6(IL-6) / 血液前駆細胞の体外増幅 / EGF受容体、組み換えアデノウイルス / 上皮細胞増殖因子(EGF) / 体外増幅 / 未熟造血細胞 / コロニー / 上皮細胞増殖因子 / CD34陽性細胞 / active Notch1 / differentiation / DSL domain / EGF受容体 / CD34 / ストローマ細胞 / 自己複製能 / EGF様リピート / Notch3 / Notch2 / Notch1 / 活性化型Notch1 / DSLドメイン / Notch蛋白質 / Apoptosis / Stress / Cell growth / Leukemia / 足場非依存性増殖 / 転写伸長因子 / MLL / MEN遺伝子 / t(11;19)転座型白血病 / 増殖抑制因子 / MAP kinase / zinc finger / 核内蛋白質 / アポトーシス / ストレス刺激 / 増殖抑制 / smad3 / myofibril / knockout mouse / subcellular localization / シグナル伝達 / アクチン線維 / myelogenous leukemias / extracellular signal-regulated kinase / 細胞増殖 / 転写活性 / Evi-1融合蛋白質 / MAPキナーゼ / レドックス制御 / 造血細胞 / 染色体転写 / 急性骨髄性白血病 / Tumor Suppressor Gene / RB Protein / p53 Gene / p16INK4A Gene / Cell Cycle / Evi-1 Gene / Blastic Crisis / Chronic Myelocytic Leukemia / RB蛋白質 / p16INK4A遺伝子 / Evi-1遺伝子 / Anti-sense / Protein-tyrosine kinase / レトロウィルス / アンチセンス / growth stimulation / differentiation suppression / CML / 増殖促進 / p16 gene / suppressor oncogene / 複合転座 / RT-PCR法 / t(15;17)転座 / RARのキメラ遺伝子 / PML / 急性前骨髄球性白血病 / 癌抑制遺 / 転写制御因子 / EVI-1 gene / EVI-1 chimeric gene / chronic myelocytic leukemia / t(3 ; 21) translocation / PCR法 / SSCP法 / 骨髄異形成症候群 / CML急性転化 / Ph^1陽性ALL / N-ras遺伝子 / メチル化阻害剤 / DNAメチル化 / HDACi / ペプチド / 白血病関連キメラ遺伝子 / ヒストン脱アセチル化酵素阻害剤 / EVI1 / Ruxn1 / Runx1 / 再発率 / 生存率 / 予後不良因子 / AML / microRNA / 血液内科学 / 赤芽球系前駆細胞 / Notchl / 骨髄支持細胞 / 幹細胞増幅 / 分化 / 赤芽球系細胞 / 骨髄系前駆細胞 / FAK / 血管拡張 / c-Src / c-Crk / actin線維の束状形成 / p130^<Cas> / 非ホジキンリンパ腫 / 急性リンパ性白血病 / MLH1遺伝子 / DNAミスマッチ修復 / Rb遺伝子 / p15遺伝子 / リンパ系腫瘍 / BCL6遺伝子 / EWS遺伝子 / FISH法 / 骨・軟部腫瘍 / 造血器腫瘍 / RAD54 / WT1 / HLA / インターフェロン / FISH / 転座関連遺伝子 / 癌遺伝子 / 受容体 / 情報伝達 / 造血因子 / 細胞内情報伝達機構 / Vav / Ash / Grb2 / インターロイキン(IL)-3 / エリスロポエチン / GM-CSF / リン酸化蛋白 / ltk蛋白質 / 細胞内シグナル伝達機構 / レセプター型チロシンキナーゼ / ヒトltk遺伝子 Less

小児・AYA世代におけるMDSの発生機序と治療戦略の解明
- Principal Investigator
  
  平林真介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
Molecular pathogenesis and molecular therapy in RUNX1-EVI1-type leukemia.Principal Investigator
- Principal Investigator
  
  Mitani Kinuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Dokkyo Medical University
Analysis of molecular mechanisms in RUNX1-EVI1-type leukemiaPrincipal Investigator
- Principal Investigator
  
  Mitani Kinuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Analysis of mechanisms in hematopoietic regulation by transcription factorsPrincipal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Basic research on new therapy for leukemia by a decoy peptide.
- Principal Investigator
  
  MAKI Kazuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Analysis of RUNX1-target genes and their functions
- Principal Investigator
  
  YAMAGATA Tetsuya
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Molecular mechanism and molecular targeting therapy in transIocation-related leukemia.Principal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
Analysis of mechanisms in hematopoietic regulation and leukemia developmentPrincipal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
発生工学的手法を用いた白血病関連転写因子の機能解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
発生工学的手法を用いた白血病関連転写因子TELの機能解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Mechanisms in hematopoiesis and leukemogenesis by the transcription factor TELPrincipal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
12P13転座型白血病の分子機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
OP9cDNAライブラリーを用いた新規造血幹細胞増殖因子のクローニングPrincipal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
転写因子異常による白血病発症の分子機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Dokkyo Medical University
コンディショナルマウスを用いたヒト白血病関連転写因子の機能解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Dokkyo Medical University
Development of new immune cell therapies with human leukemia model mouse.Principal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo University School of Medicine
11q23転座型白血病の分子機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Analysis of molecular mechanisms in leukemogenesis by chimeric transcription factorsPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Yuichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Dokkyo University School of Medicine
  The University of Tokyo
Notch in hematopoiesis
- Principal Investigator
  
  CHIBA Shigeru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo Hospital
Analyses of Maltipotential Functions of a Novel Signaling Molecule, Cas
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Cell biology
- Research Institution
  University of Tokyo
ノックアウトマウスを用いた新規情報伝達物質p130^<Cas>の生物学的機能解析
- Principal Investigator
  
  小川誠司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
発生工学的手法を用いたヒト白血病モデルマウスの作製Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
造血幹細胞複製因子の同定・単離とその実用化
- Principal Investigator
  
  平井久丸
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
基本転写因子異常による造血幹細胞腫瘍化の機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Analyses of a Novel Signaling Molecule, Cas
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  University of Tokyo
Analysis of molecular mechanisms of leukemia development
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Practical development of a novel method for hematopoietic stem cell expansion
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Ex vivo expansion of hematopoietic stem cells using adenovirus
- Principal Investigator
  
  CHIBA Shigeru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo
造血幹細胞腫瘍白血病化の分子機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
転座関連遺伝子によるがんの診断・病態研究
- Principal Investigator
  
  鎌田七男
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
造血器腫瘍の予後に関する遺伝子診断法の開発
- Principal Investigator
  
  平井久丸
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analysis of transcription factor abnormality in the progression of preleukemic state.Principal Investigator
- Principal Investigator
  
  MITANI Kinuko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo University
造血因子のレセプターからRasに至る細胞内情報伝達機構
- Principal Investigator
  
  花園豊
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒト前白血病における転写因子異常の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
骨髄異形成症候群発症の分子機構の解析Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analysis of Molecular Mechanism of Blastic Crisis in Chronic Myelocytic Leukemia
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokyo
Functional analysis of AML1 gene in normal hematopoietic cells and leukemia cells
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo
造血細胞のチロシンキナーゼを介する情報伝達機構
- Principal Investigator
  
  HANAZONO Yutaka
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
慢性骨髄性白血病急性転化の分子機構Principal Investigator
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
造血細胞特異的受容体型チロシンキナーゼ,ltkに対する増殖因子と生理的意義の解析
- Principal Investigator
  
  豊島秀男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Molecular analysis of leukemias with chromosomal translocation and its application for clinical Diagnosis
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo
A novel gene therapy against human leukemias : suppression of protein-tyrosine kinase activities
- Principal Investigator
  
  MANO Hiroyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
  The University of Tokyo
Molecular Diagnosis of Human Leukemias
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tokyo
Development and clinical application of molecular diagnosis in leukemias
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo

[Journal Article] Emergence of t(3;21)(q26.2;q22) during eltrombopag treatment in a patient with relapsed aplastic anemia who received chemotherapy for angioimmunoblastic T-cell lymphoma.2022
- Author(s)
  Nakamura F, Nakamura Y, Nannya Y, Arai H, Shimbo K, Nakamura Y, Seo S, Sasaki K, Ichikawa M, Ogawa S, Mitani.
- Journal Title
  
  Leukemia Research Reports
  
  Volume: 17 Pages: 100305-100305
- DOI
  10.1016/j.lrr.2022.100305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08822
[Journal Article] Clonal hematopoiesis in adult pure red cell aplasia2021
- Author(s)
  Fujishima N、Kohmaru J、Koyota S、Kuba K、Saga T、Omokawa A、Moritoki Y、Ueki S、Ishida F、Nakao S、Matsuda A、Ohta A、Tohyama K、Yamasaki H、Usuki K、Nakashima Y、Sato S、Miyazaki Y、Nannya Y、Ogawa S、Sawada K、Mitani K、Hirokawa M
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2253-2253
- DOI
  10.1038/s41598-021-81890-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08709, KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-19K08822
[Journal Article] PECAM is an effective and safe anthracycline-containing regimen for patients with relapsed or refractory non-Hodgkin lymphoma.2021
- Author(s)
  Nakamura　F, Arai　H, Tokita　K, Furuichi　S, Sugita-Nagasawa　F, Takahashi　W, Handa　T, Iso　H, Tadokoro　J, Tsurumi　S, Nakamura　Y, Nakamura　Y, Sasaki　K, Seo　S, Ichikawa　M, Mitani K.
- Journal Title
  
  Leukemia & Lympho
  
  Volume: 62 Issue: 1 Pages: 239-242
- DOI
  10.1080/10428194.2020.1817442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08822
[Journal Article] Development of Philadelphia chromosome-negative acute myeloid leukemia with IDH2 and NPM1 mutations in a patient with chronic myeloid leukemia who showed a major molecular response to tyrosine kinase inhibitor therapy.2021
- Author(s)
  Nakamura F, Arai H, Nannya Y, Ichikawa M, Furuichi S, Nagasawa F, Takahashi W, Handa T, Nakamura Y, Tanaka H, Nakamura Y, Sasaki K, Miyano S, Ogawa S, Mitani K.
- Journal Title
  
  Int J Hematol
  
  Volume: 113 Issue: 6 Pages: 936-940
- DOI
  10.1007/s12185-020-03074-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-19H05656
[Journal Article] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia.2021
- Author(s)
  Ochi Y, Yoshida K, Huang YJ, Kuo MC, Nannya Y, Sasaki K, Mitani K, et al.
- Journal Title
  
  Nat comm
  
  Volume: 12 Issue: 1 Pages: 2833-2833
- DOI
  10.1038/s41467-021-23097-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-20K22809, KAKENHI-INTERNATIONAL-15K21741, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-20K08127, KAKENHI-PROJECT-20K08723
[Journal Article] . Efficacy and safety of romiplostim in refractory aplastic anaemia: a Phase II/III, multicentre, open-label study.2020
- Author(s)
  Jang JH, Tomiyama Y, Miyazaki K, Nagafuji K, Usuki K, Uoshima N, Fujisaki T, Kosugi H, Matsumura I, Sasaki K, Kizaki M, Sawa M, Hidaka M, Kobayashi N, Ichikawa S, Yonemura Y, Enokitani K, Matsuda A, Ozawa K, Mitani K, Lee JW, Nakao S.
- Journal Title
  
  Br J Haematol.
  
  Volume: 192 Issue: 1 Pages: 190-199
- DOI
  10.1111/bjh.17190
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08326, KAKENHI-PROJECT-19K08822
[Journal Article] Continuous lenalidomide treatment after　bortezomib-melphalan-prednisolone　therapy for newly diagnosed multiple myeloma.2020
- Author(s)
  Ishida T, Hideo Kimura H, Ozaki S, Kubo K, Sunami K, Takezako N, Fujita H, Hayashi8 T, Toru Kiguchi T, Ohashi K, Yamamoto S, Takamatsu H, Kosugi H, Ohta K, Sakai R, Handa H, Kondo Seiji, Abe Y, Omoto E, Mitani K, Morita S, Murakami H, Shimizu K.
- Journal Title
  
  Annals of Hematology
  
  Volume: - Issue: 5 Pages: 1063-1072
- DOI
  10.1007/s00277-020-03988-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08822
[Journal Article] The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.2020
- Author(s)
  Naka K, Ochiai R, Matsubara E, Kondo C, Yang KM, Hoshii T, Araki M, Araki K, Sotomaru Y, Sasaki K, Mitani K, Kim D-W, Ooshima A, Kim SJ.
- Journal Title
  
  Nature Comm
  
  Volume: 11 Issue: 1 Pages: 4681-4681
- DOI
  10.1038/s41467-020-18491-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-19H03690, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-19H01056
[Journal Article] RUNX1-EVI1 induces dysplastic hematopoiesis and acute leukemia of the megakaryocytic lineage in mice.2018
- Author(s)
  Nakamura Y, Ichikawa M, Oda H, Yamazaki I, Sasaki K, Mitani K.
- Journal Title
  
  Leukemia Res
  
  Volume: 74 Pages: 14-20
- DOI
  10.1016/j.leukres.2018.09.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09858
[Journal Article] Validation of the revised International Prognostic Scoring System in patients with myelodysplastic syndrome in Japan: results from a prospective multicenter registry2017
- Author(s)
  Kawabata H, Tohyama K, Matsuda A, Araseki K, Hata T, Suzuki T, Kayano H, Shimbo K, Zaike Y, Usuki K, Chiba S, Ishikawa T, Arima N, Nogawa M, Ohta A, Miyazaki Y, Mitani K, Ozawa K, Arai S, Kurokawa M, Takaori-Kondo A
- Journal Title
  
  International Journal of Hematology
  
  Volume: 106 Issue: 3 Pages: 375-384
- DOI
  10.1007/s12185-017-2250-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-16K09858, KAKENHI-PROJECT-17K09026
[Journal Article] Chronic myelogenous leukemia in chronic phase transforming into acute leukemia under treatment with dasatinib 4 months after diagnosis.2016
- Author(s)
  Nakamura Y, Tokita T, Nagasawa F, Takahashi W, Nakamura Y, Sasaki K, Ichikawa M, Mitani K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 103 Issue: 3 Pages: 348-353
- DOI
  10.1007/s12185-015-1909-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09858
[Journal Article] Somatic mosaicism in chronic myeloid leukemia in remission.2016
- Author(s)
  Mitani K, Nagata Y, Sasaki K, Yoshida K, Chiba K, Tanaka H, Shiraishi Y, Miyano S, Makishima H, Nakamura Y, Nakamura Y, Ichikawa M, Ogawa S.
- Journal Title
  
  Blood.
  
  Volume: 128 Issue: 24 Pages: 2863-2866
- DOI
  10.1182/blood-2016-06-723494
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K09858
[Journal Article] 骨髄異形成症候群(MDS)関連遺伝子2011
- Author(s)
  牧和宏、三谷絹子
- Journal Title
  
  血液フロンティア 21
  
  Pages: 109-116
- Data Source
  KAKENHI-PROJECT-20390275
[Journal Article] 骨髄異形成症候群の染色体・遺伝子異常と予後2010
- Author(s)
  中村由香、三谷絹子
- Journal Title
  
  血液・腫瘍科 61
  
  Pages: 398-402
- Data Source
  KAKENHI-PROJECT-20390275
[Journal Article] Enhanced expression of the EVI1 gene in NUP98/H0XA-expressing leukemia cells.2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Ohyashiki K, Yamagat a T, Mitani K.
- Journal Title
  
  Int. J. Hematol. 89
  
  Pages: 253-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Enhanced expression of the EVII gene in NUP98/HOXA-expressing leukemia cells.2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Ohyashiki K, Yamagata T, Mitani K
- Journal Title
  
  Int J Hematol 89
  
  Pages: 253-256
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Leukaemia-related transcription factor TEL/ETV6 expands erythroid precursors and stimulates haemoglobin synthesis.2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Maki K, Porcher C, Shimizu R, Yamamoto M, Mitani K.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 689-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390275
[Journal Article] Mediastinal large B-cell lymphoma associated with systemic sclerosis2009
- Author(s)
  Arai H, Iso H, Arai Y, Tadokoro J, Nakamura Y, Yamagata T, Mitani K
- Journal Title
  
  Rinsho Ketsueki 50
  
  Pages: 97-101
- NAID
  10024958988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Enhanced expression of the EVI1 gene in NUP98/HOXA-expressing leukemia cells.2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Ohyashiki K, Yamagata T, Mitani K
- Journal Title
  
  Int J Hematol 89
  
  Pages: 253-256
- NAID
  10025160451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390275
[Journal Article] Enhanced expression of the EVI1 gene in NUP98/HOXA-expressing leukemia cells2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Ohyashiki K, Yamagata T, Mitani K
- Journal Title
  
  International Journal of Hematology 89
  
  Pages: 253-256
- NAID
  10025160451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Mediastinal large B-cell lymphoma associated with systemic sclerosis.2009
- Author(s)
  Arai H, Iso H, Arai Y, Tadokoro J, Nakamura Y, Yamagata T, Mitani K
- Journal Title
  
  Rinsho Ketsueki 50
  
  Pages: 97-101
- NAID
  10024958988
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Mediastinal large B-cell lymphoma associated with systemic sclerosis.2009
- Author(s)
  Arai H, Iso H, Arai Y, Tadokoro J, Nakamura Y, Yamagata T, Mitani K.
- Journal Title
  
  Rinsho Ketsueki. 50
  
  Pages: 97-101
- NAID
  10024958988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Enhanced expression of the EVI1 gene in NUP98/HOXA-expressing leukemia cells2009
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Ohyashiki K, Yamagata T, Mitani K
- Journal Title
  
  Int J Hematol 89
  
  Pages: 253-256
- NAID
  10025160451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera.2008
- Author(s)
  Sasaki K, Yamagata T, Mitani K
- Journal Title
  
  Cancer Sci 99
  
  Pages: 414-422
- NAID
  10024002884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390275
[Journal Article] Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera2008
- Author(s)
  Sasaki K, Yamagata T, Mitani K
- Journal Title
  
  Cancer Science 99
  
  Pages: 414-422
- NAID
  10024002884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Role of the RUNX1-EVI1 fusion gene in leukemogenesis.2008
- Author(s)
  Maki K, Yamagata T, Mitani K
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1878-1883
- NAID
  10024011504
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Role of the RUNX1-EVI1 fusion gene in leukemogenesis.2008
- Author(s)
  Maki K, Yamagata T. Mitani K.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1878-1883
- NAID
  10024011504
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera.2008
- Author(s)
  Sasaki K, Yamagata T, Mitani K
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 414-422
- NAID
  10024002884
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera2008
- Author(s)
  Sasaki K, Yamagata T, Mitani K
- Journal Title
  
  Cancer Sci 99
  
  Pages: 414-422
- NAID
  10024002884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] RUNX1/EVI1 that blocks myeloid differentiation inhibits CCAAT-enhancer binding protein α function2007
- Author(s)
  Tokita K, Maki K, Mitani K
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1752-1757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Low-level expression of ETV6/TEL in patients with Myelodysplastic syndrome.2007
- Author(s)
  Yamagata T, Nakamura Y, Mitani K
- Journal Title
  
  Int J Hematol 86
  
  Pages: 282-285
- NAID
  10019798960
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Chronic ldiopathic myeloflbrosis expressing a novel type of TEL-FDGFRB chimaera responded to imatinib mesylate therapy.2007
- Author(s)
  Tokita K, Maki K, Tadokoro J, Nakamura Y, Arai Y, Sasaki K, Eguchi-Ishimae M, Eguchi M, Mitani K.
- Journal Title
  
  Leukemia 21
  
  Pages: 190-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Low expression of ETV6/TEL found in patients with myelodysplastic syndrome2007
- Author(s)
  Yamagata T, Nakamura Y, Mitani K
- Journal Title
  
  Int J Hematol 86
  
  Pages: 282-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Chronic idiopathic myelofibrosis expressing a novel type of TEL-PDGFRB chimaera responded to imatinib mesylate therapy2007
- Author(s)
  Tokita K, Maki K, Tadokoro J, Nakamura Y, Arai Y, Sasaki K, Eguchi-Ishimae M, Eguchi M, Mitani K
- Journal Title
  
  Leukemia 21
  
  Pages: 190-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Low expression of ETV6/TEL found in patients with myelodysplastic syndrome.2007
- Author(s)
  Yamagata T, Nakamura Y, Mitani K.
- Journal Title
  
  Int J Hematol 86
  
  Pages: 282-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] RUNX1/EVI1 that blocks myeloid differentiation inhibits CCAAT-enhancer binding protein・function.2007
- Author(s)
  Tokita K, Maki K, Mitani K.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1752-1757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Low-Level Expression of ETV6/TEL in Patients with Myelodysplastic Syndrome2007
- Author(s)
  Yamagata T, Nakamura Y, Mitani K.
- Journal Title
  
  International Journal of Hematology 86
  
  Pages: 282-285
- NAID
  10019798960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Low-level expression of ETV6/TEL in atients with myelodysplastic syndrome2007
- Author(s)
  Yamagata T, Nakamura Y, Mitani K
- Journal Title
  
  International Journal of Hematology 86
  
  Pages: 82-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] TEL/ETV6 binds to corepressor KAP1 via the HLF domain2006
- Author(s)
  Nakamura Yuka
- Journal Title
  
  International Journal of Hematology 84・4
  
  Pages: 377-380
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] A solid tumor of donor cell-origin after allogeneic peripheral blood stem cell transplantation.2006
- Author(s)
  Arai Y, Arai H, Aoyagi A, Yamagata T, Mitani K, Kubota K, Kawamata H, Imai Y
- Journal Title
  
  Am J Transplant 6
  
  Pages: 3042-3043
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Development of megakaryoblastic leukaemia in Runxl-Evil knock-in chimaeric mouse.2006
- Author(s)
  Maki K, Yamagata T, Yamazaki I, Oda H, Mitani K
- Journal Title
  
  Leukemia 20
  
  Pages: 1458-1460
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] A novel TEL/ETV6 binding protein KAP1 does not contribute to its transcription-repressive activity.2006
- Author(s)
  Nakamura Y
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Development of megakaryo-blastic leukemia in Runx1-Evi1 knock- in chimaeric mouse.2006
- Author(s)
  Maki K, Yamagata T, Yamazaki I, Oda H, Mitani K.
- Journal Title
  
  Leukemia 20
  
  Pages: 1458-1460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways2006
- Author(s)
  Yamagata T, Maki K, Waga K, Mitani K
- Journal Title
  
  Biochem Biophys Res Comm 347
  
  Pages: 517-526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] TEL/ETV6 binds to corepressor KAP1 via the HLH domain2006
- Author(s)
  Nakamura Y, Yamagata T, Maki K, Sasaki K, Kitabayashi I, Mitani K
- Journal Title
  
  International Journal of Hematology 84
  
  Pages: 377-380
- NAID
  10019259868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] A novel TEL/ETV6 binding protein KAP1 does not contribute to its transcription-repnessiue activity.2006
- Author(s)
  Nakamura Y, Maki K, Sasaki K, Kitabayashi I, Mitani K.
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Development of megakaryo-blastic leukemia in Runx1-Evi1 knock- in chimaeric mouse2006
- Author(s)
  Maki K, Yamagata T, Yamazaki I, Oda H, Mitani K
- Journal Title
  
  Leukemia 20
  
  Pages: 1458-1460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] TEL/ETV6 binds to corepressor KAP1 via the HLH domain.2006
- Author(s)
  Nakamura Y, Yamagata T, Maki K, Sasaki K, Kitabayashi I, Mitani K
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- NAID
  10019259868
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] Development of megakaryoblastic leukaemia in Runx1-Evi1 knock-in chimaeric mouse2006
- Author(s)
  Maki K, Yamagata T, Yamazaki I, Oda H, Mitani K
- Journal Title
  
  Leukemia 20
  
  Pages: 1458-1460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways2006
- Author(s)
  Yamagata T, Maki K, Waga K, Mitani K
- Journal Title
  
  Biochemical and Biophysical Research Communications 347
  
  Pages: 517-526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] A novel TEL/ETV6 binding protein KAP1 does not contribute to its transcription-repressive activity.2006
- Author(s)
  Nakamura Y
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] novel TEL/ETV6 binding protein KAP1 does not contribute to its transcription-repressive activity2006
- Author(s)
  Nakamura Y, Maki K, Sasaki K, Kitabayashi I, Mitani K
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways.2006
- Author(s)
  Yamagata T, Maki K, Waga K, Mitani K
- Journal Title
  
  Biochem Biophys Res Commun. 347
  
  Pages: 517-526
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] A solid tumor of donor cell-origin after allogeneic peripheral blood stem cell transplantation2006
- Author(s)
  Arai Y, Arai H, Aoyagi A, Yamagata T, Mitani K, Kubota K, Kawamata H, Imai Y
- Journal Title
  
  American Journal of Transplantation 6
  
  Pages: 3042-3043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591086
[Journal Article] TEL/ETV6 induces apoptosis in 32D cells through p53-dependent pathways.2006
- Author(s)
  Yamagata T, Maki K, Waga K, Mitani K
- Journal Title
  
  Biochem Biophys Res Comm 347
  
  Pages: 517-526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] A novel TEL/ETV6 binding protein KAP1 does not contribute to its transcription-repressive activity.2006
- Author(s)
  Nakamura Y
- Journal Title
  
  Int J Hematol 84
  
  Pages: 377-380
- Data Source
  KAKENHI-PROJECT-17659295
[Journal Article] Cloning and characteri-zation of a novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12)(p13q13)2005
- Author(s)
  Nakamura F, Nakamura Y, Maki K, Sato Y, Mitani K
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance.2005
- Author(s)
  Seo, S., Asai, T., Saito, T., Suzuki, T., Morishita, Y., Nakamoto, T., Ichikawa, M., Yamamoto, G., Kawazu, M., Yamagata, T., Sakai, R., Mitani, K., Ogawa, S., Chiba, S., Hirai, H.
- Journal Title
  
  J Immunol 75
  
  Pages: 3492-3501
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Cloning and characteri-zation of a novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12) (p13q13).2005
- Author(s)
  Nakamura F, Nakamura Y, Maki K, Sato Y, Mitani K.
- Journal Title
  
  cancer Res 65
  
  Pages: 6612-6621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Cloning and characterization of a novel chimeric gene TEL/PTPRR in acut myelogenous leukemia with inv (12)(p13q13).2005
- Author(s)
  Nakamura F
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Data Source
  KAKENHI-PROJECT-17659295
[Journal Article] Cloning and characterization of a novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12)(p13q13)2005
- Author(s)
  Nakamura, F.
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Dysplastlc definitive hematopoiesis in Aml1//EVi-1 knock-in embryos.2005
- Author(s)
  Maki K, YamagataT, Asai T, Yamazaki I, Oda H, Hirai H, Mitani K.
- Journal Title
  
  Blood 106
  
  Pages: 2147-2155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] TEL/ETV6 accelerates erythroid differentiation and inhiblts megakaryocytlc maturation in a human leukemia cell line UT-7/GM.2005
- Author(s)
  Takahashi W, Sasaki K, Komatsu N, Mitani K
- Journal Title
  
  Cancer Sci 96
  
  Pages: 340-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Cloning and characterization of a novel chimeric gene TEL/PTPRR in acute myelogenous leukemia with inv(12)(p13q13).2005
- Author(s)
  Nakamura, F., Nakamura, Y, Maki, K., Sato, Y., Mitani, K.
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT-7/GM2005
- Author(s)
  Takahashi W, Sasaki K, Komatsu N, Mitani K
- Journal Title
  
  Cancer Sci 96
  
  Pages: 340-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Dysplastic definitive hematopoiesis in AML1/Evi-1 knock-in embryos2005
- Author(s)
  Maki K, Yamagata T, Asai T, Yamazaki I, Oda H, Hirai H, Mitani K
- Journal Title
  
  Blood 106
  
  Pages: 2147-2155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Cloning and characterization of a novel chimeric gene TEL/PTPRR in acut myelogenous leukemia with inv(12)(p13q13).2005
- Author(s)
  Nakamura F
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Data Source
  KAKENHI-PROJECT-17016068
[Journal Article] Runx1/AML1 in normal and abnormal hematopoiesis.2005
- Author(s)
  Yamagata, T., Maki, K., Mitani, K.
- Journal Title
  
  Int J Hematol 82
  
  Pages: 1-8
- NAID
  10016602492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT-7/GM.2005
- Author(s)
  Takahashi, W., Sasaki, K., Komatsu, N., Mitani, K.
- Journal Title
  
  Cancer Sci 96
  
  Pages: 340-348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Dysplastic definitive hematopoiesis in AML1/Evi-1 knock-in embryos.2005
- Author(s)
  Maki, K., Yamagata, T., Asai, T., Yamazaki, I., Oda, H., Hirai, H., Mitani, K.
- Journal Title
  
  Blood 106
  
  Pages: 2147-2155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Cloning and characterization of a novel chimeric gene TEL/PTPRR in acut myelogenous leukemia with inv(12)(p13q13).2005
- Author(s)
  Nakamura F
- Journal Title
  
  Cancer Res 65
  
  Pages: 6612-6621
- Data Source
  KAKENHI-PROJECT-17390283
[Journal Article] Functional domains of Runx1 are differentially required for CD4 repression, TCRb, and CD4/9 double negative to CD4/8 double positive transition in thymocyte development.2004
- Author(s)
  Kawazu, M., Asai, T., Ichikawa, M., Yamamoto, G., Saito, T., Goyama, S., Mitani, K., Miyazono, K., Chiba, S., Ogawa, S., Kurokawa, M., Hirai, H.
- Journal Title
  
  J Immunol 174
  
  Pages: 3526-3533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Molecular mechanisms of leukemogenesis by AML1/EVI-l.2004
- Author(s)
  Mitani K
- Journal Title
  
  Oncogene 23
  
  Pages: 4263-4269
- Data Source
  KAKENHI-PROJECT-14657248
[Journal Article] Molecular mechanisms of leukemogenesis by AML1/EVI-1.2004
- Author(s)
  Mitani K
- Journal Title
  
  Oncogene 23
  
  Pages: 4263-4269
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region.2004
- Author(s)
  Goyama, S., Yamaguchi, Y., Imai, Y., Kawazu, M., Nakagawa, M., Asai, T., Kumano, K., Mitani, K., Ogawa, S., Chiba, S., Kurokawa, M., Hirai, H.
- Journal Title
  
  Blood 104
  
  Pages: 3558-3564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Molecular mechanisms of leukemogenesis by AML1/EVI-1.2004
- Author(s)
  Mitani K.
- Journal Title
  
  Oncogene 23
  
  Pages: 4263-4269
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] TEL/AML1 shows dominant-negative effects over TEL as well as AML1.2004
- Author(s)
  Gunji, H., Waga, K., Nakamura, F., Maki, K., Sasaki, K., Nakamura, Y., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 322
  
  Pages: 623-630
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.2004
- Author(s)
  Imai, Y., Kurokawa, M., Yamaguchi, Y., Izutsu, K., Nitta, E., Mitani K., Satake, M., Noda, T., Ito, Y., Hirai, H.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 1033-1043
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukemia-related transcription factor TEL is negatively regulated through ERK-induced phosphorylation.2004
- Author(s)
  Maki, K., Arai, H., Waga, K., Sasaki, K., Nakamura, F., Imai, Y., Kurokawa, M., Hirai, H., Mitani K.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 3227-3237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Molecular mechanisms of leukemogenesis by AML1/EVI-l.2004
- Author(s)
  Mitani K
- Journal Title
  
  Oncogene 23
  
  Pages: 4263-4269
- Data Source
  KAKENHI-PROJECT-13218117
[Journal Article] AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.2004
- Author(s)
  Ichikawa, M., Asai, T., Saito, T., Yamamoto, G., Seo, S., Yamazaki, I., Yamagata, T., Mitani K., Chiba, S., Ogawa, S., Kurokawa, M., Hirai, H.
- Journal Title
  
  Nat Med 10
  
  Pages: 299-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.2004
- Author(s)
  Yamaguchi, Y., Kurokawa, M., Imai, Y., Izutsu, K., Asai, T., Ichikawa, M., Yamamoto, G., Nitta, E., Yamagata, T., Sasaki, K., Mitani K., Ogawa, S., Chiba, S., Hirai, H.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 15630-15638
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Molecular mechanisms of leukemogenesis by AML1/EVI-1.2004
- Author(s)
  Mitani, K.
- Journal Title
  
  Oncogene 23
  
  Pages: 4263-4269
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Functional analysis of a dominant-negative DETS TEL/ETV6 isoform.2004
- Author(s)
  Sasaki, K., Nakamura, Y., Maki, K., Waga, K., Nakamura, F., Arai, H., Imai, Y., Hirai, H., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 317
  
  Pages: 1128-1137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Monocytic leukemia with CALM/AF10 rearrangement showing mediastinal emphysema.2003
- Author(s)
  Nakamura, F.
- Journal Title
  
  Am J Hematol 72
  
  Pages: 138-142
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Should young patients with e19a2 type BCR/ABL rearrangement undergo stem cell transplantation.2003
- Author(s)
  Nakamura, F.
- Journal Title
  
  Leuk & Lymph 44
  
  Pages: 381-382
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Should young patients with e19a2 type BCR/ABL rearrangement undergo stem cell transplantation.2003
- Author(s)
  Nakamura, F., Ogawa, S., Izutsu, K., Imai, Y., Maki, K., Yamagata, T., Mitani, K., Hirai, H.
- Journal Title
  
  Leuk & Lymph 44
  
  Pages: 381-382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Monocytic leukemia with CALM/AF10 rearrangement showing mediastinal emphysema.2003
- Author(s)
  Nakamura, F., Maki, K., Arai, Y., Nakamura, Y, Mitani, K.
- Journal Title
  
  Am J Hematol 72
  
  Pages: 138-142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells.2003
- Author(s)
  Waga, K., Nakamura, Y., Maki, K., Arai, H., Yamagata, T., Sasaki, K., Kurokawa, M., Hirai, H., Mitani K.
- Journal Title
  
  Oncogene 22
  
  Pages: 59-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.2003
- Author(s)
  Qiao, Y., Ogawa, S., Hangaishi, A., Yuji, K., Izutsu, K., Kunisato, A., Imai, Y., Wang, L., Hosoya, N., Nannyg, Y., Sato, Y., Maki, K., Mitani K., Hirai, H.
- Journal Title
  
  Leukemia 17
  
  Pages: 1112-1120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Expression of the TEL/EVI1 fusion transcript in a patient with chronic myelogenous leukemia with t(3;12)(q26;p13).2002
- Author(s)
  Nakamura, Y., Nakazato, H., Sato, Y., Furusawa, S., Mitani K.
- Journal Title
  
  Am J Hematol 69
  
  Pages: 80-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Expression of the TEL/EVI1 fusion transcript in a patient with chronic myelogenous leukemia with t(3;12)(q26;p13).2002
- Author(s)
  Nakamura, Y.
- Journal Title
  
  Am J Hematol 69
  
  Pages: 80-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Mutational analyses of the AML1 gene in patients with myelodysplastic syndrome.2002
- Author(s)
  Imai, Y., Kurokawa, M., Izutsu, K., Hangaishi, A., Maki, K., Ogawa, S., Chiba, S., Mitani K., Hirai, H.
- Journal Title
  
  Leuk & Lymph 43
  
  Pages: 617-621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Functional regulation of TEL by p38-induced phosphorylation.2002
- Author(s)
  Arai, H., Maki, K., Waga, K., Sasaki, K., Nakamura, Y., Imai, Y., Kurokawa, M.,.Hirai, H., Mitani, K.
- Journal Title
  
  Biochem Biophys Res Comm 299
  
  Pages: 116-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] The t(3 ; 21) fusion product, AML1/Evi-1, blocks AML1-induced transactivation by recruiting CtBP.2002
- Author(s)
  Izutsu, K., Kurokawa, M., Imai, Y., Ichikawa, M., Asai, T., Maki, K., Mitani K., Hirai, H.
- Journal Title
  
  Oncogene 21
  
  Pages: 2695-2703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] N-ras and p53 gene mutations in Japanese patients with myelo-proliferative disorders.2002
- Author(s)
  Tsurumi, S., Nakamura, Y., Maki, M., Omine, M., Fujita, K., Okamura, T., Niho, Y., Hashimoto, S., Kanno, K., Suzuki, K., Hangaishi, A., Ogawa, S., Hirai, H.Mitani, K.
- Journal Title
  
  Am J Hematol 71
  
  Pages: 131-133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370308
[Journal Article] Leukaemia-related trans-cription factor TEL/ETV6 expands erythroid precursors and stimulates haemoglobin synthesis
- Author(s)
  Eguchi-Ishimae M, Eguchi M, Maki K, Porcher C, Shimizu R, Yamamoto M, Mitani K
- Journal Title
  
  Cancer Sci (in press)
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390283
[Presentation] 急性白血病の分子病態と分子標的療法.2021
- Author(s)
  三谷絹子
- Organizer
  日本癌治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] Clonal evolution and clinical impact of genetic lesions in blast crisis of chronic myeloid leukemia.2021
- Author(s)
  越智　陽太郎、吉田　健一、南谷　泰仁、佐々木　光、三谷　絹子、小川　誠司等
- Organizer
  日本血液学会　関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] ASXL1 mutations predict a poor response to darbepoetin alfa in anemic patients with low-risk MDS.2020
- Author(s)
  Hirohiko Shibayama, Yasuyoshi Morita, Motoshi Ichikawa, Yasuhito Nannya, Hitoshi Hanamoto, Yoshinobu Maeda, Tomoko Hata, Toshihiro Miyamoto, Hiroshi Kawabata, Kazuto Takeuchi, Hiroko Tanaka, Junji Kishimoto, Satoru Miyano, Itaru Matsumura, Seishi Ogawa, Koichi Akashi, Yuzuru Kanakura, Kinuko Mitani
- Organizer
  第82回日本血液学会学術集会総会
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] ASXL1 Mutations Predict a Poor Response to Darbepoetin Alfa in Anemic Patients with Low-risk MDS: A Multicenter, Phase II Study.2020
- Author(s)
  Hitoshi Hanamoto, Yasuyoshi Morita, Motoshi Ichikawa, Yasuhito Nannya, Hirohiko Shibayama, Yoshinobu Maeda, Tomoko Hata, Toshihiro Miyamoto, Hiroshi Kawabata, Kazuto Takeuchi, Hiroko Tanaka, Junji Kishimoto, Satoru Miyano, Itaru Matsumura, Seishi Ogawa, Koichi Akashi, Yuzuru Kanakura, Kinuko Mitani.
- Organizer
  第62回米国血液学会
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] Prognostic Relevance of Genetic Abnormalities in Blastic Transformation of Chronic Myeloid Leukemia.2020
- Author(s)
  Yotaro Ochi, Kenichi Yoshida, Ko Sasaki, Yasuhito Nannya, Hideki Makishima, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Masashi Sanada, Satoru Miyano, Kinuko Mitani, Seishi Ogawa, et al.
- Organizer
  第62回米国血液学会
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] Myelodysplastic syndromes ~Recent progresses in molecular and immune therapies~.2019
- Author(s)
  Kinuko Mitani
- Organizer
  5th Asean Federation of Hematology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] 慢性骨髄性白血病の病態進展におけるMIR9の機能.2019
- Author(s)
  佐々木光、永澤英子、吉田健一、竹田淳恵、白石友一、千葉健一、田中洋子、岡田　愛、宮野　悟、市川　幹、小川誠司、三谷絹子
- Organizer
  第56回日本臨床分子医学会学術集会.
- Data Source
  KAKENHI-PROJECT-19K08822
[Presentation] AMLの分子標的療法と分子病態2018
- Author(s)
  三谷絹子
- Organizer
  第115回日本内科学会総会・講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09858
[Presentation] RUNX1-EVI1 キメラ遺伝子による白血病モデルマウスの解析.2017
- Author(s)
  中村由香、市川幹、小田秀明、山崎家春、佐々木光、三谷絹子
- Organizer
  第54回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09858
[Presentation] RUNX1-EVI1 fusion gene induces an acute megakaryoblastic leukemia in mice.2016
- Author(s)
  Yuka Nakamura, Motoshi Ichikawa, Ieharu Yamazaki, Ko Sasaki, Kinuko Mitani
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09858
[Presentation] Presidential Lecture Leukemogenesis by RUNX1-EVI1 and afterward stories ～a message to young doctors and researchers～.2016
- Author(s)
  Kinuko Mitani
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-16K09858
[Presentation] Dysregulated gene and microRNA expression of MDS.2011
- Author(s)
  Maki K, Mitani K.
- Organizer
  JSH International Symposium 2011 in Nagasaki.
- Place of Presentation
  長崎
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-20390275
[Presentation] Molecular pathogenesis of MDS and its clinical implications2010
- Author(s)
  牧和宏、三谷絹子
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591140
[Presentation] Abnormal expression of mir-9 indicates poor prognosis in AML patients.2010
- Author(s)
  Maki K, Yamagata T, Sasaki K, Mitani K.
- Organizer
  15^<th> Congress of EHA.
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-20390275
[Presentation] Molecular pathogenesis of MDS and its clinical implication.2010
- Author(s)
  Maki K, Sasaki K, Yamagata T, Mitani K.
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20390275
[Presentation] microRNA-9の高発現は急性白血病において予後不良を示す2009
- Author(s)
  山形哲也, 佐々木光, 牧和宏, 三谷絹子
- Organizer
  第71回日本血液総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] microRNA-9の高発現は急性白血病において予後不良を示す2009
- Author(s)
  山形哲也, 佐々木光, 牧和弘, 三谷絹子
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 白血病関連転写因子のmicroRNA による制御2009
- Author(s)
  山形哲也・三谷絹子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] microRNAによるTELの発現制御機構の解析およびMDS発症への関与の検討2008
- Author(s)
  佐々木光, 山形哲也, 牧和弘, 三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Roles of leukemia-related transcription factor TEL in erythropoiesis2008
- Author(s)
  Mitani K
- Organizer
  第8回国際ポルフィリン・ヘムシンポジウム
- Place of Presentation
  島根
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-17390283
[Presentation] MDS症例におけるmicroRNAの発現解析2008
- Author(s)
  山形哲也, 三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] ヒストン脱アセチル化酵素阻害剤を用いたRunx1/Evilの造腫瘍活性の抑制2008
- Author(s)
  牧和宏, 佐々木光, 山形哲也, 三谷絹子
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 白血病関連転写因子のmicroRNAによる制御2008
- Author(s)
  山形哲也, 三谷絹子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] microRNAによるTELの発現制御機構の解析およびMDS発症への関与の検討2008
- Author(s)
  佐々木光, 山形哲也, 牧和弘, 三谷絹子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] ヒストン脱アセチル化酵素阻害薬を用いたRUNX1/EVI1の造腫瘍活性の抑制2008
- Author(s)
  牧和宏、山形哲也、佐々木光、三谷絹子
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20591140
[Presentation] microRNA によるTEL の発現制御機構の解析およびMDS 発症への関与の検討2008
- Author(s)
  佐々木光、山形哲也、牧和弘、三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] MDS症例におけるmicroRNAの発現解析2008
- Author(s)
  山形哲也, 三谷絹子
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] ヒストン脱アセチル化酵素阻害剤を用いたRunx1/Evi1の造腫瘍活性の抑制2008
- Author(s)
  牧和弘, 佐々木光, 山形哲也, 三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] microRNAによるTELの発現制御機構の解析およびMDS発症への関与の検討2008
- Author(s)
  佐々木光, 山形哲也, 牧和宏, 三谷絹子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] microRNAによるTELの発現制御機構の解析およびMDS発症への関与の検討2008
- Author(s)
  佐々木光, 山形哲也, 牧和宏, 三谷絹子
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 再発・難治性CD33陽性急性骨髄性白血病に対するCAG-GO療法の安全性と有効性2008
- Author(s)
  仲村祐子, 新井幸宏, 山形哲也, 三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 白血病関連転写因子のmicroRNAによる制御2008
- Author(s)
  山形哲也, 三谷絹子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] MDS 症例におけるmicroRNA の発現解析2008
- Author(s)
  山形哲也・三谷絹子
- Organizer
  第70回日本血液総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 白血病関連転写因子のmicroRNAによる制御2008
- Author(s)
  山形哲也、三谷絹子
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20390275
[Presentation] 再発・難治性CD33陽性急性骨髄性白血病に対するCAG-GO療法の安全性と有効性2008
- Author(s)
  仲村祐子, 新井幸宏, 高橋渉, 鴇田勝哉, 新井ほのか, 半田智幸, 田所治朗, 磯桐子, 鶴見茂治, 牧和宏, 佐々木光, 山形哲也, 三谷絹子
- Organizer
  第70回日本血液学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] MDS 症例におけるp53 関連経路の解析2007
- Author(s)
  山形哲也, 中村由香, 三谷絹子
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会(合同総会)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 中枢神経原発悪性リンパ腫治療の検討2007
- Author(s)
  田所治朗, 新井幸宏, 鴇田勝哉高橋渉, 磯桐子, 新井ほのか, 半田智幸, 仲村祐子, 石前峰斉, 江口真理子, 佐々木光, 牧和宏, 山形哲也, 三谷絹子
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Runx1キメラ型白血病細胞に対するヒストン脱アセチル化酵素阻害剤の作用機序の解析2007
- Author(s)
  佐々木光、山形哲也、三谷絹子
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会(合同総会)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Runx1キメラ型白血病細胞に対するヒストン脱アセチル化酵素阻害剤の作用機序の解析2007
- Author(s)
  佐々木光, 山形哲也, 三谷絹子
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] MDS症例におけるp53関連経路の解析2007
- Author(s)
  山形哲也, 中村由香, 三谷絹子
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Normal and abnormal hematopoiesis by leukemia-related transcription factor TEL2007
- Author(s)
  Mitani K
- Organizer
  USA-Japan Cooperative Cancer Research Program
- Place of Presentation
  Kauai
- Year and Date
  2007-03-21
- Data Source
  KAKENHI-PROJECT-17390283
[Presentation] MDS症例におけるp53関連経路の解析2007
- Author(s)
  山形哲也, 中村由香, 三谷絹子
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Normal and abnormal hematopoiesis by leukemia-related transcription factor TEL.2007
- Author(s)
  Mitani K
- Organizer
  USA-Japan Cooperative Cancer Research Program
- Place of Presentation
  Kauai
- Year and Date
  2007-03-21
- Data Source
  KAKENHI-PROJECT-17016068
[Presentation] アセチル化によるTELの機能制御2007
- Author(s)
  牧和宏, 山形哲也, 北林一生, 三谷絹子
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] inv(16)あるいはt(8;21)型急性骨髄性白血病症例のKIT変異の解析2007
- Author(s)
  高橋渉, 山形哲也, 田所治朗, 新井幸宏, 三谷絹子
- Organizer
  第69回日本血液学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] アセチル化によるTELの機能制御2007
- Author(s)
  牧和弘、山形哲也、北林一生、三谷絹子
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会(合同総会)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 多発性骨髄腫におけるビフォスフォネート投与と骨代謝マーカー2006
- Author(s)
  半田智幸, 高橋渉, 新井ほのか, 田所治朗, 仲村祐子, 石前峰斉, 江口真理子, 佐々木光, 牧和宏, 新井幸宏, 山形哲也, 三谷絹子
- Organizer
  第68回日本血液学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] 新規TEL結合蛋白KAP-1の同定と機能解析2006
- Author(s)
  中村由香, 山形哲也, 牧和宏, 佐々木光, 北林一生, 三谷絹子
- Organizer
  第68回日本血液学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] AMLI/EvilによるC/EBPaの抑制効果2006
- Author(s)
  鴇田勝哉, 牧和宏, 佐々木光, 山形哲也, 三谷絹子
- Organizer
  第68回日本血液学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] AML1/Evi1によるC/EBPaの抑制効果2006
- Author(s)
  鴇田勝哉, 牧和宏, 佐々木光, 山形哲也, 三谷絹子
- Organizer
  第65回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Runx1-Evi1ノックインキメラマウスの急性巨核芽球性白血病の発症2006
- Author(s)
  牧和宏, 山形哲也, 山崎家春, 小田秀明, 三谷絹子
- Organizer
  第68回日本血液学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18591086
[Presentation] Dysplastic definitive hematopoiesis in AML1/Evi-1 knock-in mice.2005
- Author(s)
  Mitani K
- Organizer
  The 8^<th> International symposium on myelodysplastic syndrome
- Place of Presentation
  Nagasaki
- Year and Date
  2005-05-13
- Data Source
  KAKENHI-PROJECT-17016068
[Presentation] Dysplastic definitive hematopoiesis in AML1/Evi-1 knock-in mice2005
- Author(s)
  Mitani K
- Organizer
  The 8^<th> International symposium on myelodysplastic syndrome
- Place of Presentation
  Nagasaki
- Year and Date
  2005-05-13
- Data Source
  KAKENHI-PROJECT-17390283

1. OGAWA Seishi (60292900)

# of Collaborated Projects: 20 results

# of Collaborated Products: 1 results
2. HIRAI Hisamaru (90181130)

# of Collaborated Projects: 17 results

# of Collaborated Products: 0 results
3. SASAKI Ko (60282638)

# of Collaborated Projects: 17 results

# of Collaborated Products: 51 results
4. CHIBA Shigeru (60212049)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
5. MAKI Kazuhiro (50337391)

# of Collaborated Projects: 13 results

# of Collaborated Products: 62 results
6. HONDA Hiroaki (40245064)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
7. HANAZONO Yutaka (70251246)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
8. TANAKA Tomoyuki (50227154)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
9. NAKAMURA Yuichi (20227896)

# of Collaborated Projects: 8 results

# of Collaborated Products: 14 results
10. WAGA Kazuo (00285917)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
11. KUROKAWA Mineo (80312320)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
12. TETSUYA Yamagata (30424047)

# of Collaborated Projects: 5 results

# of Collaborated Products: 61 results
13. 宮川清 (40200133)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
14. TAKAHASHI Tokiharu (30313125)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
15. MARIKO Eguchi (40420781)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
16. MINENORI Eguchi (50420782)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
17. MANO Hiroyuki (90240704)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
18. 中村由香 (80364595)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
19. 豊島秀男 (20197966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 市川幹 (60463840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
21. HIRANO Naoto

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. 杉本耕一

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. SAKAI Ryuichi (40215603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 鎌田七男 (00034629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 田中耕三 (00304452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 田中公夫 (70116622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 阿部達生 (60079746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 広沢信作 (50143574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 森茂郎 (30010424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 瀬戸加大 (80154665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 大木操 (00158792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 平林真介 (50769635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 真部淳 (20292849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 鳴海覚志 (40365317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 小野澤真弘 (70455632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. UENO Hiroo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. KUMANO Keiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. TAKAHASHI Tsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. WITTE Owen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. QWEN Witte

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 鈴木隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 冨山佳昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 石田文宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 牧島秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

mitani kinuko 三谷 絹子

Mitani Kinuko 三谷 絹子

MITANI Kinuko 三谷 絹子

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular pathogenesis and molecular therapy in RUNX1-EVI1-type leukemia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanisms in RUNX1-EVI1-type leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of mechanisms in hematopoietic regulation by transcription factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism and molecular targeting therapy in transIocation-related leukemia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of mechanisms in hematopoietic regulation and leukemia developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発生工学的手法を用いた白血病関連転写因子の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

発生工学的手法を用いた白血病関連転写因子TELの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms in hematopoiesis and leukemogenesis by the transcription factor TELPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

12P13転座型白血病の分子機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

OP9cDNAライブラリーを用いた新規造血幹細胞増殖因子のクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

mitani kinuko 三谷絹子

Mitani Kinuko 三谷絹子

MITANI Kinuko 三谷絹子