takuwa yo 多久和陽

… Alternative Names

TAKUWA Yoh 多久和陽

多久和陽タクワアキラ

多久和陽タクワヨウ

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Researcher Number	60171592
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 医学系, 協力研究員
Affiliation (based on the past Project Information) *help	2020: 金沢大学, 医学系, 協力研究員 2008 – 2019: Kanazawa University, 医学系, 教授 2001 – 2007: 金沢大学, 医学系研究科, 教授 1998 – 2001: Kanazawa Uni., Physiology, Professor, 医学部, 教授 1998 – 1999: 金沢大学, 医学部・第一生理, 教授 … More 1998: Kanazawa University School of Medicine, Professor, 医学部・生理学第一講座, 教授 1997: 国際科学振興財団, 研究開発部, 主任研究員 1997: 国際科学振興財団, 研究開発部, 専任研究員 1997: Foundation for Advancement of International Science, Research Chief, 主任研究員 1996: University of Tokyo, Faculty of Medicine, Dept.of Cardiovascular Biology, Associate Professor, 医学部, 客員助教授 1996: 東京大学, 医学部・附属病院, 助教授 1991 – 1995: 東京大学, 医学部(医), 客員助教授 1991: 筑波大学, 基礎医学系, 講師 1988 – 1990: 筑波大学, 臨床医学系, 講師 Less
Review Section/Research Field	Principal Investigator General physiology / General physiology / Biological Sciences / Pathological medical chemistry / Biological Sciences / 血管生物学 Except Principal Investigator General surgery / General physiology / Basic Section 55030:Cardiovascular surgery-related / Cerebral neurosurgery
Keywords	Principal Investigator Rac / スフィンゴシン-1-リン酸 / Rho / 血管 / Edg / AGR-16 / EDG / イノシトールリン脂質 / 細胞運動 / sphingosine-1-phosphate … More / 受容体 / PI3-キナーゼ / 脂質メディエーター / 病態生理 / 脂質 / PI3キナーゼ / ノックアウトマウス / 遊走 / 転移 / 浸潤 / 内皮 / 平滑筋 / エンドセリン / カルシウムイオン / cell motility / ノックアウト / Receptor / 細胞遊走 / 情報伝達 / ATP / P_2受容体 / ホスファターゼ / 生理学 / 生体分子 / シグナル伝達 / 小胞輸送 / PI 3-キナーゼ / 炎症 / 血管新生 / がん / Edg受容体 / S1P / 血管平滑筋 / G蛋白共役型受容体 / リン酸化 / ミオシン軽鎖 / 平滑筋収縮 / PI-3-P / エンドサイトーシス / エンドソーム / 細胞内小胞輸送 / スフィンゴシンキナーゼ / スフィンゴ脂質 / トランスジェニック / マウス / gene targeting / Cell migration / Sphingosme-1-phosphate / トランスジェニックマウス / 形態形成 / 器官形成 / EDG受容体 / cell migration / Signal transduction / スフィゴシン-1-リン酸 / G protein / P_2 receptor / JNK / Signalling / Mechanical force / PTHrP / Blood vessels / 遺伝子発現 / 副甲状腺ホルモン関連ペプチド / 機械力 / 伸展 / Signal transductions / Vasoactive Substances / Purines / Blood Vessel / P_1受容体 / プリン作動性 / G蛋白 / 情報伝達機構 / 生理活性物質 / プリン体 / ミオシン軽鎖キナーゼ / Cキナーゼ / フォスファターゼ / 小胞 / ホスホイノシチド / スフィンゴシン－1－リン酸 / 循環器疾患 / 循環器・高血圧 / 血管医学 / 血管障壁 / スフィンゴシンー１－リン酸 / イノシトールリン酸 / 血管障害 / アナフィラキシー / 動脈瘤 / 血管透過性 / 血管障壁機能 / 血管恒常性 / 分子病態学 / ホメオスターシス / 心血管 / SIP / SIP_2 / 血管成熟 / S1P_2 / フィンゴシン-1-リン酸 / 癌 / PDGF受容体 / アンチセンス治療法 / バルーン血管障害 / 内膜肥厚 / 血管狭窄 / クローニング / cDNA / 血管内皮 / Ca^<2+>チャネル / ホスホリパーゼA_2 / ホスホリパーゼC / G蛋白質 / 収縮 / カルデスモン / カルシウムチャンネル / フォスフォリパ-ゼC / プロティンキナ-ゼC … More Except Principal Investigator PDGFXR / PDGF / adenovirus / JNK / neointimal SMC / cerebral vasospasm / PDGF-B chain / ATP / 遺伝子治療 / thrombomodulin / 脳血管攣縮 / 一酸化窒素 / 内皮機能 / 血管内皮 / 冠動脈バイパス術 / experimental vasospasm / Ca^<2+> sensitization / vasocontraction / subarachnoid hemorrhage / Dephosphorylation / Calcium sensitization / Vascular smooth muscle / Myosin light chain kinase / Cerebral vasospasm / endothelin / protein kinase C / sphingosine 1-phosphate / calcium sensitization / phosphorylation / myosin binding subunit / myosin light chain kinase / rho kinase / vascular smooth muscle / 実験的くも膜下出血モデル / Ca^<2+>感受性 / 血管収縮 / くも膜下出血 / angiotensin II / neointimal formation / 内膜平滑筋細胞 / アンギオテンシン II / neointinal SHC / ERK / アンギオテンシンII / neointinal SMC / gene expression / signal transduction / P_0 purinoceptor / mechanical stretch / smooth muscle / vascular / P2受容体 / P_2受容体 / 遺伝子発現 / シグナル伝達 / P_2 受容体 / 機械力 / 血管平滑筋 / アデノウィルスベクタ / Angiotensinll / 内膜肥厚 / plasminogen activators / endothelial cell / hybrid-type vascular prosthesis / small caliber vascular prosthesis / 小口径人工血管 / 血管内皮細胞 / thrombomonodulin / tissue plasminegen activator / Plasminogen activators / tissue plasminogen activator / ハイブリッド型人工血管 / 内皮細胞 / ボンベシン / ジアシルグリセロール / タキキニン / エンドセリン / 肺小細胞癌 / カルシウム / Cキナーゼ / 増殖因子 / 分子機構 / 生理機能 / ヌクレオチド / ATP受容体 / big ET / 内皮細胞腫瘍 / ET受容体 / ホスホラミドン / 変換酵素 / bigET / アイソフォーム / エンドセリン(ET) Less

Effects of perivascular tissue on endothelial function of internal thoracic artery in CABG
- Principal Investigator
  
  Iino Kenji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kanazawa University
Regulation of vascular cell function through control of membrane traffic by cellular lipid signalingPrincipal Investigator
- Principal Investigator
  
  Takuwa Yoh
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
炎症制御因子としてのスフィンゴシン－１－リン酸の血管障害における役割Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Control of vascular barrier integrity by MTM family of phosphatidylinositol 3-phosphate phosphatasePrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Mechanisms for the regulation of vascular homeostasis by functional lipid moleculesPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
炎症制御因子としてのスフィンゴシン－１－リン酸の血管障害における役割Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Disruption of vascular integrity by deficiency of PI3K class II αisoform in micePrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Role of functionallipids in cardiovascular homeostasis and diseasesPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Signaling for regulating hematogenous metastasis of tumorsPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Interrated research on the physiological role ofbioactive sphingosine-1-phosphate and Edg receptors by using genetically engineered maice.Principal Investigator
- Principal Investigator
  
  TAKUWA Yho
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズムPrincipal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズムPrincipal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Molecular dissection of the physiological role of bioactive sphingosine-1-phosphate and Edg receptorsPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yho
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Molecular biological analysis of the lipid morphogen sphingosine-1-phosphatePrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Ca^<2+> sensitization and deficiency of myosin light chain dephosphorylation in the pathogenesis of cerebral vasospasm
- Principal Investigator
  
  SASAKI Tomio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Gunma University
Molecular biological research of biological functions of the sphingoshine-1-phosphate receptorsPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General physiology
- Research Institution
  kanazawa University
The role of PDGF-B chain after vascular injury
- Principal Investigator
  
  MIYATA Tetsuro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
ATP受容体の生理機能と分子機構に関する総合的基礎研究
- Principal Investigator
  
  山下勝幸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Osaka University
Molecular Mechanisms for Mechanotransduction in Vascular Smooth Muscle and Endothelial cell
- Principal Investigator
  
  TAKUWA Noriko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  The University of Tokyo
Development of hybrid-type vascular prosthesis with application of gene transfer technique
- Principal Investigator
  
  MIYATA Tetsuro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Molecular analysis and gene transfer to vascular stenosis
- Principal Investigator
  
  IMANISHI Hiroaki, 佐藤紀
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  University of Tokyo
Molecular mechanisms for local regulation of vascular tonicsPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  University of Tokyo
バルーン血管障害後の内膜肥厚発症の分子機構の解明およびアンチセンス治療法の開発Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  The University of Tokyo
血管平滑筋及び内皮に発現する新しいG蛋白質共役型受容体の機能の解析Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
血管内皮の産生する生理活性ペプチドエンドセリン-1の血管平滑筋作用機構の研究Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular Characterization of Purinergic Receptor and its Signal Transduction in the Vascular SystemPrincipal Investigator
- Principal Investigator
  
  TAKUWA Yoh
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  University of Tokyo
血管内皮の生産する生理活性ペプチドエンドセリンー1の血管平滑筋作用機序の研究Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エンドセリンの薬理学的研究
- Principal Investigator
  
  真崎知生, 眞崎智生 (眞崎知生)
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tsukuba
  Kyoto University
カルシウムイオンによる平滑筋収縮の分子機構の解明Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba
異なる細胞増殖因子間に生ずる協同相乗作用の分子機構の研究
- Principal Investigator
  
  多久和典子
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
カルシウムイオンによる平滑筋収縮の分子機構の解明Principal Investigator
- Principal Investigator
  
  多久和陽
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba

[Book] なるほどなっとく！解剖生理学2017
- Author(s)
  多久和典子、多久和陽
- Total Pages
  297
- Publisher
  南山堂
- ISBN
  9784525121617
- Data Source
  KAKENHI-PROJECT-15H04673
[Book] Bioactive Lipid Mediators: Current Reviews and Protocols.2015
- Author(s)
  Takuwa N, OkamotoY, Yoshioka K and Takuwa Y
- Total Pages
  426
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15H04673
[Book] サイトカイン・増殖因子キーワード2015
- Author(s)
  多久和　陽
- Total Pages
  422
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15H04673
[Book] Vascular Biology Update2007
- Author(s)
  尾山治、多久和陽
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-17014034
[Book] Signaling mechanisms for positive and negative regulation of cell motility by sphingosine-1-phosphate receptors. (Y. Hirabayashi, Y. Igarashi, A.H.Merrill(Eds.), Sphingolipid Biology)2006
- Author(s)
  Y. Takuwa, N. Sugimoto, N. Takuwa, Y. Igarasi, Y. Hirabayashi
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17014034
[Book] Sphingolipid Biology.2006
- Author(s)
  Yoh Takuwa
- Total Pages
  531
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17390054
[Book] Sphingolipid Biology.2006
- Author(s)
  Yoh Takuwa et al.
- Total Pages
  531
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17014034
[Book] Sphingolipid Biology2006
- Author(s)
  Yoh Takuwa
- Total Pages
  531
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease.2018
- Author(s)
  Lee J-Y, Han S-H, Par M-H, Baek B, Song I-S, Choi M-K, Takuwa Y, Ryu H, He X, Schuchman E, Bae J-S, Jin H-K, Kim S-H.
- Journal Title
  
  Nat Commun
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04673
[Journal Article] Photoacoustic imaging of tumor vascular permeability with indocyanine green in a mouse model.2018
- Author(s)
  Okumura K, Yoshida K, Yoshioka K, Aki S, Yoneda N, Inoue D, Kitao A, Ogi T, Kozaka K, Minami T, Koda W, Kobayashi S, Takuwa Y and Gabata T
- Journal Title
  
  European Radiology Experimental
  
  Volume: 2: 5 Issue: 1 Pages: 1-9
- DOI
  10.1186/s41747-018-0036-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-16K10343, KAKENHI-PROJECT-16K19812
[Journal Article] Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.2017
- Author(s)
  Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D and Gavalas A.
- Journal Title
  
  PLOS Biology
  
  Volume: 15 (3) Issue: 3 Pages: e2000949-e2000949
- DOI
  10.1371/journal.pbio.2000949
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-26460292
[Journal Article] Early endothelialization associated with a biolimus A9 bioresorbable polymer stent in a porcine coronary model.2017
- Author(s)
  Mori M, Sakata K, Nakanishi C, Nakahashi T, Kawashiri MA, Yoshioka K, Takuwa Y, Okada H, Yokawa JI, Shimojima M, Yoshimuta T, Yoshida S, Yamagishi M, Hayashi K.
- Journal Title
  
  Heart Vessels.
  
  Volume: 32 Issue: 10 Pages: 1244-1252
- DOI
  10.1007/s00380-017-0992-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-15H04673
[Journal Article] Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo.2017
- Author(s)
  Funaki M, Kitabayashi J, Shimakami T, Nagata N, Sakai Y, Takegoshi K, Okada H, Murai K, Shirasaki T, Oyama T, Yamashita T, Ota T, Takuwa Y, Honda M, Kaneko S.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 16978-16978
- DOI
  10.1038/s41598-017-17285-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-16K21058, KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-15K08492
[Journal Article] Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.2017
- Author(s)
  Ohkura SI, Usui S, Takashima SI, Takuwa N, Yoshioka K, Okamoto Y, Inagaki Y, Sugimoto N, Kitano T, Takamura M, Wada T, Kaneko S, Takuwa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 8 Pages: e0182329-e0182329
- DOI
  10.1371/journal.pone.0182329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17K08532, KAKENHI-PROJECT-17K08542, KAKENHI-PROJECT-15H04673, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-15K10970, KAKENHI-PROJECT-17H04166
[Journal Article] Sphingosine-1-phosphate receptor type 2 (S1P_2) inhibits bleomycin-induced cellular senescence in murine lung fibroblasts.2016
- Author(s)
  Zhao J, Okamoto Y, Takuwa Y.
- Journal Title
  
  金沢大学十全医学会雑誌
  
  Volume: 125 Pages: 2-13
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04673
[Journal Article] Phosphatidylinositol 3-kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells.2015
- Author(s)
  Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 10 Pages: 6086-6105
- DOI
  10.1074/jbc.m114.601484
- NAID
  120005593954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26460292, KAKENHI-PROJECT-26460374, KAKENHI-PROJECT-15K10970, KAKENHI-PROJECT-15H04673
[Journal Article] Receptor for advanced glycation end products - membrane type1 matrix metalloprotease axis regulates tissue factor expression via RhoA and Rac1 activation in high-mobility group box-1 stimulated endothelial Cells.2014
- Author(s)
  Sugimoto K, Ohkawara H, Takuwa Y, Ishibashi T and Takeishi Y .
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 12 Pages: 1-13
- DOI
  10.1371/journal.pone.0114429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390051, KAKENHI-PROJECT-24591100, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162
[Journal Article] スフィンゴシン-1-リン酸の炎症における多彩な役割2014
- Author(s)
  多久和　陽
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 138-146
- Data Source
  KAKENHI-PROJECT-25670162
[Journal Article] Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.2014
- Author(s)
  Ishikura K, Misu H, Kumazaki M, Takayama H, Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T
- Journal Title
  
  Diabetologia
  
  Volume: 57 Issue: 9 Pages: 1968-1976
- DOI
  10.1007/s00125-014-3306-9
- NAID
  120005463349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PUBLICLY-25122710, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329
[Journal Article] Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells2014
- Author(s)
  Igarashi J, Hashimoto T, Kubota Y, Shoji K, Maruyama T, Sakakibara N, TakuwaY, Ujihara Y, Katanosaka Y, Mohri S, Naruse K, Yamashita T, Okamoto R, Hirano K, Kosaka H, Takata M, Konishi R, Tsukamoto I.
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 2 Issue: 5 Pages: 68-68
- DOI
  10.1002/prp2.68
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390051, KAKENHI-PROJECT-24591654, KAKENHI-PROJECT-24790123, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25461132, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26220203
[Journal Article] スフィンゴシン-1-リン酸の炎症における多彩な役割2014
- Author(s)
  多久和　陽
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 138-146
- Data Source
  KAKENHI-PUBLICLY-25116711
[Journal Article] スフィンゴシン-1-リン酸の炎症における多彩な役割2014
- Author(s)
  多久和　陽
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 138-146
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through suppression of eNOS in mice.2013
- Author(s)
  Cui H, Okamoto Y, Yoshioka K, et al.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 132 Issue: 5 Pages: 1205-1214
- DOI
  10.1016/j.jaci.2013.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- NAID
  130004943837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] Sphingosine -1 -Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] 血管新生の基礎と臨床2013
- Author(s)
  多久和陽
- Journal Title
  
  Bio Clinica
  
  Volume: 28 Pages: 16-17
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] Essential role of class II PI3K-C2α in sphingosine-1-phosphate receptor-1 mediated signaling and migration in endothelial cells2013
- Author(s)
  Biswas K, Yoshioka K, Asanuma K, Okamoto Y, Takuwa N, Sasaki T, TakuwaY
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 4 Pages: 2325-2339
- DOI
  10.1074/jbc.m112.409656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-23116509
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23116509
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- NAID
  130004943837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670162
[Journal Article] CCL2/CCR2 augments the production of transforming growth factor-beta1, type 1 collagen and CCL2 by human CD45-/collagen 1-positive cells under high glucose concentrations.2013
- Author(s)
  Hara A, Sakai N, Furuichi K, Sakai Y, Takeya M, Bucala R, Mukaida N, Takuwa Y, Matsushima K, Kaneko S, Wada T.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 17 Issue: 6 Pages: 793-804
- DOI
  10.1007/s10157-013-0796-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390051, KAKENHI-PROJECT-24406028, KAKENHI-PUBLICLY-25116711, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-25670269
[Journal Article] 血管新生の基礎と臨床2013
- Author(s)
  多久和　陽
- Journal Title
  
  Bio Clinica
  
  Volume: 28 Pages: 16-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] 血管新生の基礎と臨床2013
- Author(s)
  多久和　陽
- Journal Title
  
  Bio Clinica
  
  Volume: 28 Pages: 16-17
- Data Source
  KAKENHI-PUBLICLY-23116509
[Journal Article] Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases2013
- Author(s)
  Takuwa Y
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 183 Issue: 1 Pages: 185-192
- DOI
  10.1016/j.bbalip.2012.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-22590716, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-23116509
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25116711
[Journal Article] Sphingosine-1-Phosphate Signaling and Cardiac Fibrosis.2013
- Author(s)
  Takuwa N
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 33 Pages: 96-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Sphingosine-1 -phosphate signaling in physiology and diseases2012
- Author(s)
  Takuwa Y
- Journal Title
  
  BioFactors
  
  Volume: 38 Pages: 329-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390051
[Journal Article] Essential role of endothelial class II PI3K-C2α in angiogenesis and vascular barrier function2012
- Author(s)
  Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz J.R, Okamoto H, Sasaki T, Matsui O, Asano M, Adams H.R, Takakura N, Takuwa Y
- Journal Title
  
  Nature med
  
  Volume: 18(10) Pages: 1560-1569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Sphingosine-1-phosphate signaling in physiology and diseases2012
- Author(s)
  Takuwa Y
- Journal Title
  
  BioFactors
  
  Volume: 38 Issue: 5 Pages: 329-337
- DOI
  10.1002/biof.1030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590284, KAKENHI-PROJECT-23590257, KAKENHI-PROJECT-23590344, KAKENHI-PROJECT-23659170, KAKENHI-PUBLICLY-23116509
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1 Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] G Protein-coupledsphingosine-1-phosphate receptors: potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- URL
  http://www.eurochicago.com/wp-content/uploads/2012/03/BMR-22-2011.pdf#page=22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] G Protein-coupled sphingosine-1-phosphate receptors : potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23116509
[Journal Article] Intraradial administration of fasudil inhibits augmented Rho kinase activity to effectively dilate spastic radial artery in coronary artery bypass grafting surgery2011
- Author(s)
  Takagi T, Okamoto Y, Tomita S, Sato A, Yamaguchi S, Takuwa Y, Wa tanabe G
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 142(2)
- URL
  http://dx.doi.org/10.1016/j.jtcvs.2011.01.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats2011
- Author(s)
  Suzuki H, Hashimoto H, Kawasaki M, Watanabe M, Otsubo H, Ishikura T, Fujihara H, Ohnishi H, Onuma E, Yamada-Okabe H, Takuwa Y, Ogata E, Nakamura T, Ueta Y.
- Journal Title
  
  Int J Cancer
  
  Volume: 128 Issue: 9 Pages: 2215-2223
- DOI
  10.1002/ijc.25535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-21591964
[Journal Article] Effects of gomisin A on vascular contraction in rat aortic rings Naunyn-Schmiedeberg2011
- Author(s)
  Seok YM, Choi YW, Kim GD, Kim HY, Takuwa Y, Kim IK.
- Journal Title
  
  Archives of Pharmacology
  
  Volume: 383(1) Issue: 1 Pages: 45-56
- DOI
  10.1007/s00210-010-0571-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PUBLICLY-23116509, KAKENHI-PROJECT-23659170
[Journal Article] Intraradial administration of fasudil inhibits augmented Rho kinase activity to effectively dilate spastic radial artery in coronary artery bypass grafting surgery2011
- Author(s)
  Takagi T, Okamoto Y, Tomita S, Sato A, Yamaguchi S, Takuwa Y, Watanabe G.
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 142(2) Pages: 59-65
- URL
  http://dx.doi.org/10.1016/j.jtcvs.2011.01.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Involvement of membrane type1-matrix metalloproteinase(MT1-MMP) in rage activation signalingpathways2011
- Author(s)
  Kamioka M, Ishibashi T, Ohkawara H, Eguchi R, Sugimoto K, Uekita H, Matsui T, Yamagishi SI, Ando K, Sakamoto T, Sakamoto N, Takuwa Y, Wada I, Shiomi M, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Cell Physiol
  
  Volume: 226(6) Issue: 6 Pages: 1554-1563
- DOI
  10.1002/jcp.22492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-21590340, KAKENHI-PROJECT-21590935, KAKENHI-PUBLICLY-23116509, KAKENHI-PROJECT-23659170
[Journal Article] スフィンゴシン-1-リン酸と炎症2011
- Author(s)
  多久和陽
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 41 Pages: 14-25
- Data Source
  KAKENHI-PUBLICLY-23116509
[Journal Article] スフィンゴシン-1-リン酸と炎症2011
- Author(s)
  多久和　陽
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 41 Pages: 14-25
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1 Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] G Protein-coupled sphingosine-1-phosphate receptors : potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] G Protein-coupled sphingosine-1-phosphate receptors: potential molecular targets for angiogenic and anti-angiogenic therapies.2011
- Author(s)
  Takuwa N
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1 Pages: 460-481
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23116509
[Journal Article] スフィンゴシン-1-リン酸と炎症2011
- Author(s)
  多久和陽
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 41 Pages: 14-25
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Crucial role of membrane type 1 matrix metalloproteinase(MT1-MMP) in RhoA/Rac1-dependent signaling pathways in thrombin-stimulated endothelial cells2011
- Author(s)
  Ando K, Ishibashi T, Ohkawara H, Inoue N, Sugimoto K, Uekita H, Hu C, Okamoto Y, Takuwa Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 18(9) Pages: 762-73
- URL
  http://www.jstage.jst.go.jp/article/jat/18/9/18_6783/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K Takuwa Y
- Journal Title
  
  Am J Cancer Res.
  
  Volume: 1(4) Pages: 460-481
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186046/?tool=pubmed
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659170
[Journal Article] Protein-coupled sphingosine-1-phosphate receptors : potential molecular targets for angiogenic and anti-angiogenic therapies2011
- Author(s)
  Takuwa N, Okamoto Y, Yoshioka K, Takuwa Y.
- Journal Title
  
  Biomed Rev
  
  Volume: 22 Pages: 15-29
- URL
  http://www.eurochicago.com/wp-content/uploads/2012/03/BMR-22-2011.pdf#page=22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Tumor-suppressive Sphingosine-1-phosphate Receptor-2 Counteracting Tumor-promoting Sphingosine-1-phosphate Receptor-1 and Sphingosine Kinase 1-Jekyll Hidden behind Hyde2011
- Author(s)
  Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K Takuwa Y.
- Journal Title
  
  Am J Cancer Res
  
  Volume: 1(4) Pages: 460-481
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186046/?tool=pubmed
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis Pharmaceuticals2011
- Author(s)
  Okamoto Y, Wang F, Yoshioka K, Takuwa N, Takuwa Y.
- Journal Title
  
  Atherosclerosis Pharmaceuticals
  
  Volume: 4 Issue: 1 Pages: 117-137
- DOI
  10.3390/ph4010117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species2010
- Author(s)
  Takuwa N, Ohkura S, Takashima S, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, Sugimoto N, Mizugishi K, Nakanuma Y, Ishii I, Takamura M, Kaneko S, Kojo S, Satouchi K, Mitumori K, Chun J, Takuwa Y
- Journal Title
  
  Cardiovasc Res
  
  Volume: 85(3) Issue: 3 Pages: 484-493
- DOI
  10.1093/cvr/cvp312
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-21591414, KAKENHI-PROJECT-22590284
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice2010
- Author(s)
  Qi X, Okamoto Y, Murakawa T, Wang F, Oyama O, Ohkawa R, Yoshioka K, Du W, Sugimoto N, Yatomi Y, Takuwa N, Takuwa Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 634(1-3) Issue: 1-3 Pages: 121-131
- DOI
  10.1016/j.ejphar.2010.02.038
- NAID
  120002086439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22590284
[Journal Article] JI. Hamada Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with survival of patients with glioblastoma.2010
- Author(s)
  Y. Yoshida, M. Nakada, N. Sugimoto, T. Harada, Y. Hayashi, D. Kita, N. Uchiyama, Y. Hayashi, A. Yachie, Y. Takuwa
- Journal Title
  
  Int J Cancer 126(10)
  
  Pages: 2341-2352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic miceinvolves reactive oxygen species.2010
- Author(s)
  N.Takuwa
- Journal Title
  
  Cardiovasc Res 85
  
  Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Roles of sphingosine-1-phosphate signaling in angiogenesis2010
- Author(s)
  Takuwa Y, Du W, Qi X, Okamoto Y, Takuwa N, Yoshioka K.
- Journal Title
  
  World J Biol Chem
  
  Volume: 1(10) Pages: 298-306
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083935/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Sphingosine-1-phosphate receptor type 1 regulates glioma cell proliferation and correlates with survival of patients with glioblastoma2010
- Author(s)
  Yoshida Y, Nakada M, Sugimoto N, Harada T, Hayashi Y, Kita D, Uchiyama N, Hayashi Y, Yachie A, Takuwa Y, Hamada JI.
- Journal Title
  
  Int J Cancer
  
  Volume: 126(10) Issue: 10 Pages: 2341-2352
- DOI
  10.1002/ijc.24933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22791337
[Journal Article] S1P2, the G protein-coupledreceptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice2010
- Author(s)
  Du W, Takuwa N, Yoshioka K, Okamoto Y, Gonda K, Sugihara K, Fukamizu A, Asano M, Takuwa Y.
- Journal Title
  
  Cancer Res
  
  Volume: 70(2) Issue: 2 Pages: 772-781
- DOI
  10.1158/0008-5472.can-09-2722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057, KAKENHI-PROJECT-22590284
[Journal Article] Preventive effects of pravastatin on thrombintriggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo2010
- Author(s)
  Ohkawara H, Ishibashi T, Saitoh S, Inoue N, Sugimoto K, Kamioka M, Uekita H, Kaneshiro T, Ando K, Takuwa Y, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 88(3) Issue: 3 Pages: 492-501
- DOI
  10.1093/cvr/cvq221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.2010
- Author(s)
  N. Takuwa, S. Ohkura, S. Takashima, K. Ohtani, Y. Okamoto, T. Tanaka, K, Hirano, S. Usui, F. Wang, W. Du, K. Yoshioka, Y. Banno, M. Sasaki, I. Ichi, M. Okamura, N. Sugimoto, K. Mizugishi, Y. Nakanuma, I. Ishii, M. Takamura, S. Kaneko, S. Kojo, K. Satouchi, K. Mitumori, J. Chun, Y. Takuwa
- Journal Title
  
  Cardiovasc Res 85(3)
  
  Pages: 484-493
- NAID
  120001939472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Roles of sphingosine-1-phosphate signaling in angiogenesis.2010
- Author(s)
  Y Takuwa
- Journal Title
  
  World J Biol Chem.
  
  Volume: 1 Pages: 298-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species2010
- Author(s)
  多久和陽
- Journal Title
  
  Cardiovasc Res 85
  
  Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.2010
- Author(s)
  N.Takuwa
- Journal Title
  
  Cardiovasc Res
  
  Volume: 85 Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] Y Takuwa S1P2, the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice.2010
- Author(s)
  W Du, N Takuwa, K Yoshioka, Y Okamoto, K Gonda, K Sugihara, A Fukamizu, M Asano
- Journal Title
  
  Cancer Res 70(2)
  
  Pages: 772-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.2010
- Author(s)
  X Qi, Y Okamoto, T Murakawa, F Wang, O Oyama, R Ohkawa, K Yoshioka, W Du, N Sugimoto, Y Yatomi, N Takuwa, Y Takuwa
- Journal Title
  
  Eur J Pharmacol 634
  
  Pages: 121-131
- NAID
  120002086439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Involvement of sphingosine-1-phosphate and S1P(1) in angiogenesis : Analyses using a new S1P(1) antagonist of non-sphingosine-1-phosphate analog2009
- Author(s)
  Yonesu K, Kawase Y, Inoue T, Takagi N, Tsuchida J, Takuwa Y, Kumakura S, Nara F.
- Journal Title
  
  Biochem Pharmacol
  
  Volume: 15 ; 77(6) Pages: 1011-1020
- URL
  http://dx.doi.org/10.1016/j.bcp.2008.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] RhoA and Rac1 changes in the atherosclerotic lesions of WHHLMI rabbits2009
- Author(s)
  Ohkawara H, Ishibashi T, Shiomi M, Sugimoto K, Uekita H, Kamioka M, Takuwa Y, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 16(6) Pages: 846-856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] LOX-1-LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-d nsity lipoprotein in endothelial cells2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Inoue N, Kamioka M, Uekita H, Ohkawara H, Sakamoto T, Sakamoto N, Okamoto Y, Takuwa Y, Kakino A, Fujita Y, Tanaka T, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 84(1) Issue: 1 Pages: 127-136
- DOI
  10.1093/cvr/cvp177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] 生体におけるスフィンゴシン-1-リン酸シグナル系の機能2009
- Author(s)
  多久和陽
- Journal Title
  
  実験医学 27
  
  Pages: 2068-2073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] LOX-1-LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-d nsity lipoprotein in endothelial cells2009
- Author(s)
  K. Sugimoto, T. Ishibashi, T. Sawamura, N. Inoue, M. Kamioka, H. Uekita, H. Ohkawara, T. Sakamoto, N. Sakamoto, Y. Okamoto, Y. Takuwa, A. Kakino, Y. Fujita, T. Tanaka, T. Teramoto, Y. Maruyama, Y. Takeishi
- Journal Title
  
  Cardiovasc Res 84(1)
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] 生体におけるスフィンゴシン-1-リン酸シグナル系の機能2009
- Author(s)
  多久和陽
- Journal Title
  
  実験医学 27
  
  Pages: 2068-2073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] AThe role of class II PI 3-kinase signaling pathway in physiology and diseases, Curr Biodata Targeted Proteins Database2009
- Author(s)
  Y. Takuwa
- Journal Title
  
  Bloggs, J (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Gene transduction into aortic wall using plasmid-loaded cationized gelatin hydrogel-coated polyester stent-graft.2009
- Author(s)
  H. Zhong, O. Matsui, K. Xu, T. Ogi, J. Sanada, Y. Okamoto, Y. Tabata, Y. Takuwa
- Journal Title
  
  J Vasc Surg 50(6)
  
  Pages: 1433-1443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Gene transduction into aortic wall using plasmid-loaded cationized gelatin hydrogel-coated polyester stent-graft2009
- Author(s)
  Zhong H, Matsui O, Xu K, Ogi T, Sanada J, Okamoto Y, Tabata Y, Takuwa Y.
- Journal Title
  
  J Vasc Surg
  
  Volume: 50(6) Pages: 1433-1443
- URL
  http://www.jstage.jst.go.jp/article/jat/16/6/16_2394/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] RhoA and Rac1 changes in the atherosclerotic lesions of WHHLMI rabbits.2009
- Author(s)
  H Ohkawara, T Ishibashi, M Shiomi, K Sugimoto, H Uekita, M Kamioka, Y Takuwa, T Teramoto, Y Maruyama, Y Takeishi
- Journal Title
  
  J Atheroscler Thromb 16(6)
  
  Pages: 846-856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Inhibitory effect of N-palmitoylphosphatidylethanolamine on macrophage phagocytosis through inhibition of Rac1 and Cdc422009
- Author(s)
  Shiratsuchi A, Ichiki M, Okamoto Y, Ueda N, Sugimoto N, Takuwa Y, Nakanishi Y.
- Journal Title
  
  J Biochem
  
  Volume: 145(1) Issue: 1 Pages: 43-50
- DOI
  10.1093/jb/mvn139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390057
[Journal Article] 生体におけるスフィンゴシン-1-リン酸シグナル系の機能2009
- Author(s)
  多久和陽、岡本安雄、杜娃、戚〓、吉岡和晃、多久和典子
- Journal Title
  
  実験医学 27(13)
  
  Pages: 2068-2073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Involvement of sphingosine-1-phosphate and S1P(1) in angiogenesis: Analyses using a new S1P(1) antagonist of non-sphingosine-1-phosphate analog.2009
- Author(s)
  K. Yonesu, Y. Kawase, T. Inoue, N. Takagi, J. Tsuchida, Y. Takuwa, S. Kumakura, F. Nara
- Journal Title
  
  Biochem Pharmacol 15;77(6)
  
  Pages: 1011-1020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Inhibitory effect of N-palmitoylphosphatidylethanolamine on macrophage phagocytosis through inhibition of Rac1 and Cdc422009
- Author(s)
  A. Shiratsuchi, M. Ichiki, Y. Okamoto, N. Ueda, N. Sugimoto, Y. Takuwa, Y. Nakanishi
- Journal Title
  
  J. Biochem. 145(1)
  
  Pages: 43-50
- NAID
  10024914309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependenton Rho but not Rho kinase.2008
- Author(s)
  S. Takashima, N. Sugimoto, N. Takuwa, Y. Okamoto, K. Yoshioka, M. Takamura, S. Takata, S. Kanekob, Y. Takuwa
- Journal Title
  
  Cardiovasc Res 79(4)
  
  Pages: 689-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] A case report of a renal mixed epithelial and stromal tumor in a heterozygous S1P2 receptor deficient mouse.2008
- Author(s)
  M. Takabatake, T. Takuwa, N. Takuw, H. Yasuno, S. Matsumoto, M. Shibutani, K. Mitsumori
- Journal Title
  
  J Vet Med Sci 70(5)
  
  Pages: 483-485
- NAID
  110006688954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Sphingosine-1-phosphatesignaling and biological activitiesin the cardiovascular system2008
- Author(s)
  Y. Takuwa
- Journal Title
  
  Biochim. Biophys. Acta 1781
  
  Pages: 483-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Sphingosine-1-phosphatesignaling and biological activitiesin the cardiovascular system.2008
- Author(s)
  Y. Takuwa, Y. Okamoto, K. Yoshioka, N. Takuwa
- Journal Title
  
  Biochim. Biophys. Acta 1781(9)
  
  Pages: 483-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] The lysophospholipid mediator sphingosine-1-phosphate promotes angiogenesis in vivo in ischemic hindlimbs of mice.2008
- Author(s)
  O. Oyama, N. Sugimoto, X. Qi, N. Takuwa, K. Mizugishi, J. Koizumi, Y. Takuwa
- Journal Title
  
  Cardiovasc Res 78
  
  Pages: 301-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rhoand Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  K. Yoshioka, N. Sugimoto, N. Takuwa, Y. Takuwa
- Journal Title
  
  Mol Pharmacol 71(3)
  
  Pages: 912-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Statins activate peroxisome proliferator-activated receptor gamma through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages.2007
- Author(s)
  M. Yano, T. Matsumura, T. Senokuchi, N. Ishii, Y. Murata, K. Taketa, H. Motoshima, T. Taguchi, K. Sonoda, D. Kukidome, Y. Takuwa, T. Kawada, M. Brownlee, T. Nishikawa, E. Araki
- Journal Title
  
  Circ Res 100(10)
  
  Pages: 1442-1451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Satoh Synthesis and SAR studies of a novel class of S1P(1) receptor antaeonists.2007
- Author(s)
  T.Nakamura, K.Yonesu, Y.Mizuno, C.Suzuki, Y.Sakata, Y.Takuwa, F.Nara, S.
- Journal Title
  
  Bioorg Med Chem. 15
  
  Pages: 3548-3564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion mediates geranylgeranyl transferase I and Ca2+ signaling.2007
- Author(s)
  T. Sakamoto, T. Ishibashi, K. Sugimoto, N. Sakamoto, H. Ohkawara, M. Niinuma, K. Nagata, M. Kamioka, N. Sugimoto, A. Watanabe, M. Kurabayashi, Y. Takuwa, Y. Maruyama
- Journal Title
  
  Atherosclerosis 193(1)
  
  Pages: 44-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho-and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.2007
- Author(s)
  K.Yoshioka, N.Sugimoto, N.Takuwa, Y.Takuwa
- Journal Title
  
  Mol Pharmacol. 71(3)
  
  Pages: 912-920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Hypothalamic Neuropeptides and Appetite Response in Anorexia-Cachexia Animal.2007
- Author(s)
  Y. Ueta, H. Hashimoto, E. Onuma, Y. Takuwa, E. Ogata
- Journal Title
  
  Endocr J 54(6)
  
  Pages: 831-838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Parathyroid Hormone-Related Protein Induces Cachectic Syndromes without Directly Modulating the Expression of Hypothalamic Feeding-Regulating Peptides.2007
- Author(s)
  H. Hashimoto, Y. Azuma, M. Kawasaki, H. Fujihara, E. Onuma, H. Yamada-Okabe, Y. Takuwa, E. Ogata, Y. Ueta
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 292-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Synthesis and SAR studies of a novel class of S1P(1) receptor antagonists.2007
- Author(s)
  T. Nakamura, K. Yonesu, Y. Mizuno, C. Suzuki, Y. Sakata, Y. Takuwa, F. Nara, S. Satoh
- Journal Title
  
  Bioorg Med Chem 15
  
  Pages: 3548-3564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Ueta Parathyroid Hormone-Related Protein Induces Cachectic Syndromes without Directly Modulating the Expression of Hypothalamic Feeding-Regulating Peptides.2007
- Author(s)
  H.Hashimoto, Y.Azuma, M.Kawasaki, H.Fujihara, E.Onuma, H.Yamada-Okabe, Y.Takuwa, E.Ogata, Y.
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 292-298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Ca2+-independent, inhibitory effects of cyclic AMP on Ca2+ regulation of phosphoinositide 3-kinase C2a, Rho and myosin phosphatase in vascular smooth muscle2007
- Author(s)
  MA. Azam, K. Yoshioka, S. Ohkura, N. Takuwa, N. Sugimoto, K. Sato, Y. Takuwa
- Journal Title
  
  J. Pharm. Exp. Ther 320(2)
  
  Pages: 907-916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Ca2+-independent, inhibitory effects of cyclic AMP on Ca2+ regulation of phosphoinositide 3-kinase C2a, Rho and myosin phosphatase in vascular smooth muscle.2006
- Author(s)
  MA.Azam, K.Yoshioka, S.Ohkura, N.Takuwa, N.Sugimoto, K.Sato, Y.Takuwa
- Journal Title
  
  J. Pharm.Exp.Ther 320(2)
  
  Pages: 907-916
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase.2006
- Author(s)
  R.Zheng, A.Iwase, R.Shen, OB.Goodman Jr, N.Sugimoto, Y.Takuwa, DJ.Lerner, DM.Nanus
- Journal Title
  
  Oncogene. 25(44)
  
  Pages: 5942-5952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] カルシウムイオンによる血管収縮活性化機構の新展開2006
- Author(s)
  多久和陽
- Journal Title
  
  実験医学 24(18)
  
  Pages: 2812-2816
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Takuwa Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor.2006
- Author(s)
  I.Inoki, N.Takuwa, N.Sugimoto, K.Yoshioka, S.Takata, S.Kaneko, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Takuwa Class II phosphoinositide 3-kinase alfa-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle.2006
- Author(s)
  Y.Wang, K.Yoshioka, MA.Azam, N.Takuwa, S.Sakurada, Y.Kayaba, N.sugimoto, I.Inoki, T.Kimura, T.Kuwai, Y.
- Journal Title
  
  Biochem J 394
  
  Pages: 581-592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] DM. Nanus Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase.2006
- Author(s)
  R. Zheng, A. Iwase, R. Shen, OB. Goodman Jr, N. Sugimoto, Y. Takuwa, DJ. Lerner
- Journal Title
  
  Oncogene 25(44)
  
  Pages: 5942-5952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] PKC phosphorylates MARCKS Ser159 not only directly but also through RhoA/ROCK.2006
- Author(s)
  A. Tanabe, Y. Kamisuki, H. Hidaka, M. Suzuki, M. Negishi, Y. Takuwa
- Journal Title
  
  Biochem. Biophys. Res. Commun. 345
  
  Pages: 156-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor.2006
- Author(s)
  I. Inoki, N. Takuwa, N. Sugimoto, K. Yoshioka, S. Takata, S. Kaneko, Y. Takuwa
- Journal Title
  
  Biochem. Biophys. Res. Commun. 346
  
  Pages: 293-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO sells.2006
- Author(s)
  N.Sugimoto, N.Takuwa, K.Yoshioka, Y.Takuwa
- Journal Title
  
  Exp. Cell Res. 312
  
  Pages: 1899-1908
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] スフィンゴシン1リン酸受容体による癌浸潤・転移の制御とその分子構造2005
- Author(s)
  多久和典子他
- Journal Title
  
  実験医学 23
  
  Pages: 218-223
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.2005
- Author(s)
  H. Ohkawara, T. Ishibashi, T. Sakamoto, K. Sugimoto, K. Nagata, K. Yokoyama, N. Sakamoto, M. Kamioka, I. Matsuoka, S. Fukuhara, N. Sugimoto, Y. Takuwa, Y. Maruyama
- Journal Title
  
  J Biol Chem 18;280(11)
  
  Pages: 10182-10188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] スフィンゴシン1リン酸受容体による癌浸潤・転移の制御とその分子構造2005
- Author(s)
  多久和典子
- Journal Title
  
  実験医学 23
  
  Pages: 218-223
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Maruyama Endogenous NO Blockade Enhances Tissue Factor Expression via Increased Ca2+ Influx through MCP-1 in Endothelial Cells by Monocyte Adhesion.2005
- Author(s)
  T.Sakamoto, T.Ishibashi, N.Sakamoto, K.Sugimoto, K.Egashira H.Ohkawara, K.Nagata, K.Yokoyama, M.Kamioka, T.Ichiki, N.Sugimoto, M.Kurabayashi, K.Suzuki, Y.Takuwa, Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 25(9)
  
  Pages: 2005-2011
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Sugimoto Calcium-dependent regulation of Rho and myosin phosphatase in vascular smooth muscle.2005
- Author(s)
  Y.Takuwa, K.Yoshioka, N.Takuwa, Y.Wang, MA.Azam, N.
- Journal Title
  
  Biomed. Res. 16
  
  Pages: 13-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Statins suppress oxidized low-density lipoprotein-induced macrophage proliferation by inactivation of small G protein-p38 MAPK pathway.2005
- Author(s)
  T.Senokuchi, T.Matsumura, M.Sakai, M.Yano, T.Taguchi, K.Sonoda, D.Kukidome, K.Imoto, T.Nishikawa, S.Kim-Mitsuyama, Y.Takuwa, E.Araki.
- Journal Title
  
  J. Biol. Chem. Feb 25;280(8)
  
  Pages: 6627-6633
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Eguchi Signal-Crosstalk between Rho/ROCK and JNK mediates Migration of Vascular Smooth Muscle Cells stimulated by Angiotensin.2005
- Author(s)
  H.Ohtsu, M.Mifune, G.D.Frank, S.Saito, T.Inagami, S.K.Mitsuyama, Y.Takuwa, T.Sasaki, J.D.Rothstein, H.Suzuki, H.Nakashima, E.A.Woolfolk, E.D.Motley, S.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 25
  
  Pages: 1831-1836
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Statins suppress oxidized low-density lipoprotein-induced macrophage proliferation by inactivation of small G protein -p38 MAPK pathway.2005
- Author(s)
  T. Senokuchi, T. Matsumura, M. Sakai, M. Yano, T. Taguchi, K. Sonoda, D. Kukidome, K. Imoto, T. Nishikawa, S. Kim-Mitsuyama, Y. Takuwa, E. Araki
- Journal Title
  
  J. Biol. Chem. 280(8)
  
  Pages: 6627-6633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] RhoA and Rac mediate endothelial cell polarication and detachment induced by T-cadherin.2005
- Author(s)
  M. Philippova, D. Ivanov, R. Allenspach, Y. Takuwa, P. Erne, T. Resink
- Journal Title
  
  FASEB J 19(6)
  
  Pages: 588-890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Maruyama. Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.2005
- Author(s)
  H.Ohkawara, T.Ishibashi, T.Sakamoto, K.Sugimoto, K.Nagata, K.Yokoyama, N.Sakamoto, M.Kamioka, I.Matsuoka, S.Fukuhara, N.Sugimoto, Y.Takuwa, Y.
- Journal Title
  
  J Biol Chem. 18;280(11)
  
  Pages: 10182-10188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] スフィンゴシン1リン酸受容体による癌浸潤・転移の制御とその分子構造2005
- Author(s)
  多久和典子他
- Journal Title
  
  実験医学 23(増刊)
  
  Pages: 218-223
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Inhibition of Rac activation as a mechanism for negativeregulation of actin cytoskeletal reorganization and cell motility by cyclic AMP.2005
- Author(s)
  S. Nagasawa, N. Takuwa, N. Sugimoto, H. Mabuchi, Y. Takuwa
- Journal Title
  
  Biochem J 385
  
  Pages: 737-744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] RhoA and Rac mediate endothelial cell polarication and detachment induced by T-cadherin.2005
- Author(s)
  M.Philippova, D.Ivanov, R.Allenspach, Y.Takuwa, P.Erne, T.Resink.
- Journal Title
  
  FASEB J. 19(6)
  
  Pages: 588-890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Calcium-dependent regulation of Rho and myosin phosphatase in vascular smooth muscle.2005
- Author(s)
  Yoh Takuwa
- Journal Title
  
  Biomed. Res. 16
  
  Pages: 13-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] Inhibition of Rac activation as a mechanism for negativeregulation of actin cytoskeletal reorganization and cell motility by cyclic AMP.2005
- Author(s)
  S.Nagasawa, N.Takuwa, N.Sugimoto, H.Mabuchi, Y.Takuwa.
- Journal Title
  
  Biochem J. 385
  
  Pages: 737-744
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Journal Article] スフィンゴシン1リン酸受容体による癌浸潤・転移の制御とその分子構造2005
- Author(s)
  多久和典子, 杉本直俊, 多久和陽
- Journal Title
  
  実験医学 23
  
  Pages: 218-223
- Data Source
  KAKENHI-PROJECT-17014034
[Journal Article] Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.2004
- Author(s)
  D.Shida, J.Kitayama, H.Yamaguchi, K.Hama, J.Aoki, H.Arai, H.Yamashita, K.Mori, A.Sako, T.Konishi, T.Watanabe, T.Sakai, R.Suzuki, H.Ohta, Y.Takuwa, H.Nagawa.
- Journal Title
  
  Exp Cell Res. 301(2)
  
  Pages: 168-178
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells.2004
- Author(s)
  D.Shida, T.Watanabe, T.Sakai, R.Suzuki, H.Ohta, Y.Takuwa, H.Nagawa
- Journal Title
  
  Exp Cell Res. 301
  
  Pages: 168-178
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Blood lipid mediator sphingosine-1-phosphate potently stimulates platelet derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of kruppel-like factor 5.2004
- Author(s)
  S.Usui, N.Sugimoto, N.Takuwa, S.Sakagami, S.Takata, S.Kaneko, Y.Takuwa.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 12300-12311
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Overexpression of phospholopase D prevents actinomycin D induced apoptosis through potentiation of phosphoinositide 3-kinase signaling pathways in Chinese hamster ovary cells.2004
- Author(s)
  M.Yamada, Y.Banno, Y.Takuwa, M.Koda, A.Hara, Y.Nozawa.
- Journal Title
  
  Biochem.J. 378
  
  Pages: 649-656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Inhibitory and stimulatory regulation of Rac and cell motility by the G_<12/13>-Rho-and the G_i-pathways integrated downstream of a single G protein coupled sphingosine-1-phosphate receptor isoform.2003
- Author(s)
  N.Sugimoto, N.Takuwa, H.Okamoto, S.Sakurada, Y.Takuwa.
- Journal Title
  
  Mol.Cell.Biol. 23
  
  Pages: 1534-1545
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Lysophosphatidic acid enhances metastatic potential of human colon carcinoma DLD1 cells through LPA1.2003
- Author(s)
  D.Shida, J.Kitayama, H.Yamaguchi, Y Okaji, NH.Tsuno, T.Watanabe, Y Takuwa, H.Nagawa.
- Journal Title
  
  Cancer Res. 63
  
  Pages: 1706-1711
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Divergent signals and cytoskeletal Assemblies regulate self-organizing polarity in neutrophils.2003
- Author(s)
  J.Xu, F.Wang, A.V.Keymeulen, P.Herzmark, A.Straight, K.Kelly, Y.Takuwa, N.Sugimoto, T.Mitchison, H.R.Bourne.
- Journal Title
  
  Cell 114
  
  Pages: 201-214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Antiproliferative action of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5.2003
- Author(s)
  H.Ikeda, H.Satoh, M.Yanase, Y.Inoue, T.Tomiya, M.Arai, K.Tejima, K.Nagashima, H.Maekawa, N.Yahagi, Y.Tamtomi, S.Sakurada, Y.Takuwa, I.Ogara, S.Kimura, K.Fujiwara.
- Journal Title
  
  Gastroenterology. 124
  
  Pages: 459-469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor requirement of inhibition of cellular Rac activity.2003
- Author(s)
  K.Arikawa, N.Takuwa, H.Yamaguchi, N.Sugimoto, J.Kitayama, H.Nagawa, K.Takehara, Y.Takuwa.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 32841-32851
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphatidylinositol 3-kinase or Akt, in chinese hamster ovary cells.2003
- Author(s)
  Y, Banno, Y.Takuwa, M.Yamada, N.Takuwa, K.Ohguchi, A.Hara, Y.Nozawa.
- Journal Title
  
  Biochem.J. 369
  
  Pages: 363-368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Journal Article] Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and hematogenous metastasis of melanoma cells.2003
- Author(s)
  H.Yamaguchi, J.Kitayama, N.Takuwa, K.Arikawa, I.Inoki, K.Takehara, H.Nagawa, Y.Takuwa.
- Journal Title
  
  Biochem.J. 374
  
  Pages: 715-722
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390063
[Patent] マクロファージの増殖・分化阻害又はマクロファージの老化促進による肺線維症の抑制2015
- Inventor(s)
  多久和陽、岡本　安雄
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-013793
- Filing Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15H04673
[Patent] 血管内皮関門障害に関連した疾患又は症状を予防及び/又は治療するための候補物質のスクリーニング方法2013
- Inventor(s)
  多久和陽
- Industrial Property Rights Holder
  多久和陽
- Industrial Property Number
  2013-033893
- Filing Date
  2013-02-11
- Data Source
  KAKENHI-PROJECT-23659170
[Patent] 血管内皮関門障害に関連した疾患又は症状を予防及び/又は治療するための候補物質のスクリーニング方法2013
- Inventor(s)
  多久和　陽
- Industrial Property Rights Holder
  多久和　陽
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-033893
- Filing Date
  2013-02-11
- Data Source
  KAKENHI-PROJECT-23659170
[Patent] 血管内皮関門障害に関連した疾患又は症状を予防及び/又は治療するための候補物質のスクリーニング方法2013
- Inventor(s)
  多久和陽
- Industrial Property Rights Holder
  多久和陽
- Industrial Property Number
  2013-033893
- Filing Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-24390051
[Patent] 血管内皮関門障害に関連した疾患又は症状を予防及び/又は治療するための候補物質のスクリーニング方法2013
- Inventor(s)
  多久和　陽
- Industrial Property Rights Holder
  多久和　陽
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-033893
- Filing Date
  2013-02-22
- Data Source
  KAKENHI-PUBLICLY-23116509
[Patent] 非ヒトノックアウト動物、並びにその用途およびその作製方法2011
- Inventor(s)
  多久和陽、吉岡和晃
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Industrial Property Number
  2010-090078
- Filing Date
  2011-04-09
- Data Source
  KAKENHI-PROJECT-17014034
[Patent] S1P2受容体アンタゴニストを含む、粥状動脈硬化治療薬2011
- Inventor(s)
  多久和陽、王飛、岡本安雄
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-21390057
[Patent] SIP_2受容体アンタゴニストを含む、粥状動脈硬化治療薬2011
- Inventor(s)
  多久和陽、王飛、岡本安雄
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-21390057
[Patent] 非ヒトノックアウト動物、並びにその用途およびその作製方法2010
- Inventor(s)
  吉岡和晃、多久和陽
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21390057
[Patent] 癌細胞の転移を阻害する化合物をインビボの系でスクーリングする方法2009
- Inventor(s)
  多久和陽名川弘一
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Acquisition Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-17014034
[Patent] スフィンゴシン-1-リン酸を用いた血管新生を促進する方法2005
- Inventor(s)
  多久和陽, 尾山治
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2005-145422
- Filing Date
  2005-05-18
- Data Source
  KAKENHI-PROJECT-17390054
[Patent] スフィンゴシン-1-リン酸を用いた血管新生を促進する方法2005
- Inventor(s)
  多久和陽, 尾山治
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2005-145422
- Filing Date
  2005-05-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390054
[Presentation] Myotubularin-related protein 4 (MTMR4), a phosphoinositide 3'-phosphatase, regulates endolysosome integrity and autophagy flux in human lung alveolar epithelial A549 cells2018
- Author(s)
  Pham Quynh Hoa, Yoshioka Kazuaki, Azadul Sarker Kabir, Aung Thuzar Khin, Islam Shahidul, Aki Sho, Ishimaru Kazuhiro, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Indispensable role of α and β isoforms of class II phosphoinositide 3-kinases (PI3K) in the uterine smooth muscle contraction during labor2018
- Author(s)
  Sarker Kabir Azadul, Sho Aki, Yoshioka Kazuaki, Kuno Koji, Okamoto Yasuo, Aung Thuzar Khin, Pham Quynh Hoa, Islam Shahidul, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Class II phosphoinositide 3-kinase isoforms PI3K-C2α and PI3K-C2β play essential roles in pinocytosis in vascular endothelial cells2018
- Author(s)
  Aung Thuzar Khin, Yoshioka Kazuaki, Aki Sho, Pham Quynh Hoa, Sarker Kabir Azadul, Islam Shahidul, Ishimaru Kazuhiro, Takuwa Noriko, Takuwa Yoh
- Organizer
  第 95 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Myotubularin - related protein 4 (MTMR4), a phosphoinositide 3-- specific phosphatase, regulates endolysosome integrity and autophagy flux in A549 human lung carcinoma cells2017
- Author(s)
  Quynh Hoa Pham , Kazuaki Yoshioka , Azadul Kabir Sarker , Khin Thuzar Aung , Shahidul Islam , Sho Aki , Sato Nakamura , Noriko Takuwa, Yoh Takuwa
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Phosphoinositide-specific 3'-phosphatase, myotubularin-related protein 4 (MTMR4), regulates lysosomal activity and autophagy2017
- Author(s)
  Pham Quynh Hoa, Kazuaki Yoshioka, Sato Nakamura, MD Azadul Kabir Sarker, Khin Thuzar Aung, Shahidul Islam, Sho Aki, Noriko Takuwa and Yoh Takuwa
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] 抗がん剤による臓器障害におけるスフィンゴシン-1-リン酸（S1P）情報伝達系の関与2017
- Author(s)
  多久和典子、石丸和宏、岡本安雄、多久和陽
- Organizer
  第27回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Endothelial Class II PI3K-C2α is Necessary for Vasucular Formation and Integrity through Regulating Endocytic Membrane Trafficking2017
- Author(s)
  Kazuaki Yoshioka, Sho Aki:, Noriko Takuwa:, Yoh Takuwa
- Organizer
  第81回日本循環器学会学術集会 Topic 3　「Endothelium, Health and Diseases」
- Place of Presentation
  金沢都ホテル
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Phosphotidylinositol 3-kinase Class II isoforms, PI3K-C2α and PI3K-C2β are necessary for Pinocytosis in Endothelial Cells2017
- Author(s)
  Khin Thuzar Aung, Sho Aki, Kazuaki Yoshioka, Pham Hoa Quynh , MD Azadul Kabir Sarker, Islam Shahidul, Noriko Takuwa, Yoh Takuwa.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] he announcement title: Deletion of sphingosine 1-phospahte (S1P) receptor-2 (S1P2) inhibitslung fibrosis throughaltering alveolar macrophage polarization and senescence in mice2016
- Author(s)
  Juanjuan Zhao, Yasuo Okamoto, Yoh Takuwa.
- Organizer
  Gorden research conference　“Glycolipid and Sphingolipid Biology”
- Place of Presentation
  Renaissance Tuscany Il Ciocco （Lucca (Barga), Italy）
- Year and Date
  2016-03-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Sphingosine 1-phospahte (S1P) receptor-2 (S1P2) aggravates lung fibrosis through altering alveolar macrophage polarization and cellular senescence in mice2016
- Author(s)
  JuanJuan Zhao, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa, Takashi Wada, Yutaka Inagaki, Chiaki Takahashi,Yoh Takuwa
- Organizer
  日本生化学会北陸支部第３４回大会
- Place of Presentation
  金沢大学宝町キャンパス　医学部記念館
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] PI3K-C2α is required for TGFβ-induced receptor endocytosis and endosomal signaling inendothelial cells2016
- Author(s)
  Aki Sho, Yoshioka Kazuaki, Okamoto Yasuo, Takuwa Noriko, Takuwa Yoh
- Organizer
  第93回日本生理学会
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Year and Date
  2016-03-22
- Invited
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Phosphatidylinositol 3-kinase class IIαisoform PI3K-C2α is required for transforming growth factor β-induced receptor endocytosis and endosomal signaling in endothelial cells2016
- Author(s)
  2.Sho Aki, Kazuaki Yoshioka, Yasuo Okamoto, Noriko Takuwa and Yoh Takuwa
- Organizer
  第２回春期特別日本血管生物医学会シンポジウム
- Place of Presentation
  大阪大学微生物病研究所谷口記念講堂
- Invited
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] S1P2 による血管新生と血管障壁機能の制御2016
- Author(s)
  岡本安雄、杜娃、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第58回日本脂質生化学会
- Place of Presentation
  にぎわい交流館AU（あう）
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Phosphatidylinositol 3-kinase class II α isoform PI3K-C2α is required for transforming growth factor β-induced receptor endocytosis and endosomal signaling in endothelial cells2016
- Author(s)
  Sho Aki, Kazuaki Yoshioka, Yasuo Okamoto, Noriko Takuwa , Pham Hoa Quynh , MD Azadul Kabir Sarker, Khin Thuzar Aung, Islam Shahidul, Yoh Takuwa
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] S1P2, A Receptor for the Lysophospholipid Mediator Sphingosine 1-phosphate, Protects Against Vascular Barrier Disruption2016
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  International Shock Congress Symposium "Microcirculation and endothelial damage in sepsis and shock"
- Place of Presentation
  東京ドームホテル
- Year and Date
  2016-10-03
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Role of S1P2 in inflammation and fibrosis2015
- Author(s)
  Yoh Takuwa Juanjuan Zhao, Yasuo, Okamoto, Kazuaki Yoshioka and Noriko Takuwa. Role of S1P2 in inflammation and fibrosis
- Organizer
  14 th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases Plenary Lecture
- Place of Presentation
  ハンガリーアカデミーオブサイエンス（ハンガリー　ブタペスト）
- Year and Date
  2015-07-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] クラス II PI3-キナーゼ PI3K-C2αはエンドソーム上でのTGFβ/Smad2/3シグナリングに必須である2015
- Author(s)
  安藝　翔、吉岡　和晃、岡本　安雄、多久和　典子、多久和　陽
- Organizer
  第62回中部日本生理学会
- Place of Presentation
  富山大学　五福キャンパス　黒田講堂(富山県富山市)
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Deletion of sphingosine 1-phospahte (S1P) receptor-2 (S1P-2-) inhibits lung fibrosis through altering alveolar macrophage polarization and senescence in mice.2015
- Author(s)
  Juan juan Zhao Yasuo Okamoto Kazuaki Yoshioka Sho Aki Pham Quynh Hoa Azadul MD Kabir Sarker Khin Thuzar Aung Noriko Takuwa Yutaka Inagaki Chiaki Takahashi Takashi Wada Yoh Takuwa
- Organizer
  BMB2015（第38回日本分子生物学会・第88回日本生化学会）
- Place of Presentation
  神戸ポートアイランド（神戸ポートピアホテル　神戸国際会議場　神戸国際展示場　神戸商工会議所）(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] クラスII α型PI3K-C2αはエンドソーム上でのTGFβ/Smad2/3 シグナリングに必須である2015
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋大学一橋講堂(東京)
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against anaphylaxis and acute lung injury2015
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Yoh Takuwa
- Organizer
  第10回スフィンゴテラピィ（STC）研究会
- Place of Presentation
  ホテルアローレ（石川県加賀市）
- Year and Date
  2015-06-16
- Data Source
  KAKENHI-PROJECT-15H04673
[Presentation] クラスII 型PI3K-C2αはメンブレン・トラフィック調節を介して血管バリア機能を制御する2014
- Author(s)
  吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第91回日本生理学会大会　シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII 型PI3K-C2αはメンブレン・トラフィック調節を介して血管バリア機能を制御する2014
- Author(s)
  吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第91回日本生理学会大会　シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] クラスII 型PI3K-C2αはメンブレン・トラフィック調節を介して血管バリア機能を制御する2014
- Author(s)
  吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第91回日本生理学会大会シンポジウム「心血管系の形態・機能研究の最前線」
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through inhibiting eNOS2014
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Juanjuan Zhao, Yoh Takuwa
- Organizer
  第91回日本生理学会大会 Symposium “Mechanisms on distributive shock and other blood pressure control failures”
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through inhibiting eNOS2014
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Juanjuan Zhao, Yoh Takuwa
- Organizer
  第91回日本生理学会大会　　Symposium “Mechanisms on distributive shock and other blood pressure control failures
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 protects against anaphylactic shock through inhibiting eNOS2014
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Juanjuan Zhao, Yoh Takuwa
- Organizer
  第91回日本生理学会大会　　Symposium “Mechanisms on distributive shock and other blood pressure control failures
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Endothelial PI3K-C2a2013
- Author(s)
  Yoshioka K, Yoshida K, Biswas K, Takuwa Y, et al
- Organizer
  a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express Express Ventura, (U.S.A)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII 型PI3K-C2αはSARA のエンドソームへの動員を制御しTGFß1-Smad2/3シグナル伝達系を介した血管新生を調節する2013
- Author(s)
  安藝翔，吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場/神戸国際展示場/神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] S1P2は内皮型一酸化窒素合成酵素を抑制することによりアナフラキシーショックに対して防御的に働く2013
- Author(s)
  岡本　安雄　崔　弘　吉岡　和晃　多久和　典子　多久和　陽
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘ホテル松島大観荘(宮城県宮城郡)
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIαPI3キナーゼPI3K-C2αの機能的役割2013
- Author(s)
  安藝　翔、吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Endothelial PI3K-C2a, a class II PI3K in angiogenesis and vascular barrier function2013
- Author(s)
  Yoh Takuwa
- Organizer
  Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express（ＵＳＡ）
- Year and Date
  2013-01-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-23116509
[Presentation] S1P2は内皮型一酸化窒素合成酵素を抑制することによりアナフラキシーショックに対して防御的に働く2013
- Author(s)
  岡本　安雄　崔　弘　吉岡　和晃　多久和　典子　多久和　陽
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘(宮城県宮城郡)
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 negatively regulates eNOS and protects against acute vascular barrier disruption2013
- Author(s)
  Yoh Takuwa
- Organizer
  2013FASEB Summer Research Conference Lysophospholipid and Other Related Mediators - From Bench to Clinic
- Place of Presentation
  Hilton Niseko Village（北海道虻田郡）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII 型PI3K-C2αはSARA のエンドソームへの動員を制御しTGFß1-Smad2/3シグナル伝達系を介した血管新生を調節する2013
- Author(s)
  安藝翔，吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場/神戸国際展示場/神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Endothelial PI3K-C2α, a class II PI3K in angiogenesis and vascular barrier function2013
- Author(s)
  Yoh Takuwa
- Organizer
  Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express（ＵＳＡ）
- Invited
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Endothelial P13K-C2a, a class II PI3K in angiogenesis and vascular barrier function2013
- Author(s)
  Yoh Takuwa
- Organizer
  Gordon Research Conference Vascular CeU Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express (USA)(招待講演)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII 型PI3K-C2αはSARA のエンドソームへの動員を制御しTGFß1-Smad2/3シグナル伝達系を介した血管新生を調節する2013
- Author(s)
  安藝翔，吉岡和晃，岡本安雄，多久和典子，多久和陽
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場/神戸国際展示場/神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Endothelial PI3K-C2a2013
- Author(s)
  Yoh Takuwa
- Organizer
  a class II PI3K in angiogenesis and vascular barrier function Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express Express Ventura, (U.S.A)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] ClassII PI3-kinase2013
- Author(s)
  Kuntal Biswas, Kazuaki Yoshioka, Yasuo Okamoto, Noriko Takuwa and Yoh Takuwa
- Organizer
  PI3K-C2alpha, mediates S1P-induced endothelial cell migration through endosomal Rac1 activation Gordon Reseach Conference Vascular Cell Biology
- Place of Presentation
  Four Points Sheraton / Holiday Inn Express Express Ventura, (U.S.A)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] S1P受容体はeNOS-NO経路を抑制することによりアナフラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3キナーゼ-C2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会シンポジウム「血管機能を抑制するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Phosphatidylinositol 3-kinase classII α-isoform contols vesicular trafficking in endothelial cells to serve the essential role in angiogenesis and vascular barrier integrity2013
- Author(s)
  Yoh Takuwa
- Organizer
  第45回動脈硬化学会
- Place of Presentation
  京王プラザホテル(東京都新宿区）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Sphingosine-1-phosphate receptor-2 negatively regulates eNOS and protects against acute vascular barrier disruption2013
- Author(s)
  Yoh Takuwa
- Organizer
  2013FASEB Summer Research Conference Lysophospholipid and Other Related Mediators - From Bench to Clinic
- Place of Presentation
  Hilton Niseko Village（北海道虻田郡）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Phosphatidylinositol 3-kinase classII α-isoform contols vesicular trafficking in endothelial cells to serve the essential role in angiogenesis and vascular barrier integrity2013
- Author(s)
  Yoh Takuwa
- Organizer
  第45回動脈硬化学会
- Place of Presentation
  京王プラザホテル(東京都新宿区）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] S1P受容体はeNOS-NO経路を抑制することによりアナフラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIαPI3キナーゼPI3K-C2αの機能的役割2013
- Author(s)
  安藝　翔、吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] S1P受容体はeNOS-NO経路を抑制することによりアナフラキシーショックに対して抑制的に働く2013
- Author(s)
  岡本安雄、崔弘、吉岡和晃、多久和典子、多久和陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Phosphatidylinositol 3-kinase classII α-isoform contols vesicular trafficking in endothelial cells to serve the essential role in angiogenesis and vascular barrier integrity2013
- Author(s)
  Yoh Takuwa
- Organizer
  第45回動脈硬化学会
- Place of Presentation
  京王プラザホテル(東京都新宿区）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 negatively regulates eNOS and protects against acute vascular barrier disruption2013
- Author(s)
  Yoh Takuwa
- Organizer
  2013FASEB Summer Research Conference Lysophospholipid and Other Related Mediators - From Bench to Clinic
- Place of Presentation
  Hilton Niseko Village（北海道虻田郡）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] クラスII型PI3キナーゼC2αはメンブレン・トラフィッキング調節を介する血管形成及び恒常性維持に必須である2013
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第90回日本生理学会
- Place of Presentation
  タワーホール船堀(東京都)(招待講演)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] S1P2は内皮型一酸化窒素合成酵素を抑制することによりアナフラキシーショックに対して防御的に働く2013
- Author(s)
  岡本　安雄　崔　弘　吉岡　和晃　多久和　典子　多久和　陽
- Organizer
  第55回日本脂質生化学会
- Place of Presentation
  ホテル松島大観荘(宮城県宮城郡)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] TGFβ1-Smad2/3シグナル伝達系を介した血管新生調節におけるクラスIIαPI3キナーゼPI3K-C2αの機能的役割2013
- Author(s)
  安藝　翔、吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3キナーゼ-C2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会シンポジウム「血管機能を抑制するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] クラスIIα型PI3キナーゼ-C2αによる血管新生・バリア機能調節メカニズム2013
- Author(s)
  吉岡　和晃、多久和　典子、岡本　安雄、多久和　陽
- Organizer
  第21回日本血管生物医学会　シンポジウム「血管機能を抑制するシグナリング機構」
- Place of Presentation
  千里阪急ホテル（大阪府豊中市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスIIα型PI3キナーゼC2αは血管形成に必須である2012
- Author(s)
  吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第54回日本脂質生化学会
- Place of Presentation
  九州大学医学部百年講堂(福岡県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Role of sphingosine-1-phosphate in cardiac remodeling and protection2012
- Author(s)
  Yoh Takuwa
- Organizer
  The 1st International Symposium on Lipid Mediators
- Place of Presentation
  九州大学医学部百年講堂(福岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] ラスII 型PI3キナーゼC2αはエンドソーム上でのRac1活性化を制御してスフィンゴシン-1-リン酸(S1P)による血管内皮細胞遊走・管腔形成を調節する2012
- Author(s)
  Kuntal Biswas, 吉岡和晃, 岡本安雄, 多久和典子, 多久和陽
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Essential role of class IIα-isoform P13 kinase (PI3K-C2a) in sphingosine-1-phosphate(SlP-induced endothelial cell migration2012
- Author(s)
  多久和陽
- Organizer
  第7回スフィンゴテラピィ研究会
- Place of Presentation
  能登ロイヤルホテル(石川県)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII型PI3キナーゼC2αノックアウトマウスにおける血管障壁機能の異常2012
- Author(s)
  吉岡和晃、吉田耕太朗、崔弘、安藝翔、Kuntal Biswas,趙娟娟、多久和典子、岡本安雄、多久和陽
- Organizer
  89回日本生理学会大会
- Place of Presentation
  日長野県松本文化会館(長野)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] スフィンゴシン-1-リン酸による血管内皮細胞遊走におけるクラスII型PI3キナーゼC2αの役割2012
- Author(s)
  Kuntal Biswas、吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  日長野県松本文化会館(長野)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Role of sphingosine-1'phosphate in cardiac remodeling and protection2012
- Author(s)
  Yoh Takuwa
- Organizer
  The 1st International Symposium Oil Lipid Mediators
- Place of Presentation
  九州大学医学部百年講堂(福岡県)(招待講演)
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスII型PI3キナーゼC2αは血管形成・血管恒常性維持に必須である2012
- Author(s)
  吉岡和晃, 多久和典子, 岡本安雄, 多久和陽
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)(招待講演)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Role of sphingosine-1-phosphate in cardiac remodeling and protection2012
- Author(s)
  Yoh Takuwa
- Organizer
  The 1st International Symposium on Lipid Mediators
- Place of Presentation
  九州大学医学部百年講堂（福岡県）
- Year and Date
  2012-06-06
- Invited
- Data Source
  KAKENHI-PUBLICLY-23116509
[Presentation] Essential role of class IIα-isoform PI3 kinase (PI3K-C2α) in sphingosine-1-phosphate(S1P-induced endothelial cell migration2012
- Author(s)
  多久和　陽
- Organizer
  第７回　スフィンゴテラピィ研究会
- Place of Presentation
  能登ロイヤルホテル（石川県）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Essential role of class IIα-isoform PI3 kinase (PI3K-C2α) in sphingosine-1-phosphate(S1P-induced endothelial cell migration2012
- Author(s)
  多久和　陽
- Organizer
  第７回　スフィンゴテラピィ研究会
- Place of Presentation
  能登ロイヤルホテル（石川県）
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PUBLICLY-23116509
[Presentation] 血管平滑筋収縮における新しいCa 2+ 標的―ミオシン軽鎖ホスファターゼ2011
- Author(s)
  多久和　陽
- Organizer
  第２７回スパズム・シンポジウム(招待講演)
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis 1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration2011
- Author(s)
  Yoh Takuwa, Noriko Takuwa, Seiichiro Ohkura, Shin-ichiro Takashima, Soichiro Usui2, Shuichi Kaneko, Yasuo Okamoto, Kazuaki Yoshioka
- Organizer
  第32回日本日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 血管平滑筋収縮における新しいCa2+標的-ミオシン軽鎖ホスファターゼ2011
- Author(s)
  多久和陽
- Organizer
  第27回スパズム・シンポジウム
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yoh Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis2011
- Author(s)
  Yoh Takuwa
- Organizer
  1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration and第32回日本日本炎症・再生医学会シンポジウム
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 血管平滑筋収縮における新しいCa 2+標的-ミオシン軽鎖ホスファターゼ2011
- Author(s)
  多久和陽
- Organizer
  第27回スパズム・シンポジウム
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PUBLICLY-23116509
[Presentation] Endothelial class II PI3K-Ca2a has an essential role for physiological and pathological angiogenesis2011
- Author(s)
  Kazuaki Yoshioka, Kotaro Yoshida, Hong Cui, Xun Qi, Tomohiko Wakayama, Noriko Takuwa, Yasuo Okamoto, Kazushi Sugihara, Sho Aki, Kuntal Biswas, Masahide Asano, Yo h Takuwa
- Organizer
  日本分子生物学会第11回春季シンポジウムポスタ
- Place of Presentation
  石川県立音楽堂(石川県)
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis2011
- Author(s)
  Yoh Takuwa
- Organizer
  1st Meeting of Asian-Pacific Federation of Inflammation and Regeneration and 第32回日本日本炎症・再生医学会　シンポジウム・招待講演(招待講演)
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] 血管平滑筋収縮における新しいCa2+標的-ミオシン軽鎖ホスファターゼ2011
- Author(s)
  多久和陽
- Organizer
  第27回スパズム・シンポジウム
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Function role of sphingosine-1-phosphate signaling in angiogenesis2011
- Author(s)
  Yasuo Okamoto, Xun Qi, Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  第19回日本血管生物医学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 血管平滑筋収縮における新しいCa 2+ 標的-ミオシン軽鎖ホスファターゼ2011
- Author(s)
  多久和陽
- Organizer
  第27回スパズム・シンポジウム
- Place of Presentation
  国立京都国際会館(京都府)招待講演
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23659170
[Presentation] クラスII型PI3キナーゼC2αは血管新生と障壁機能に必須である2011
- Author(s)
  吉岡和晃、吉田耕太郎、崔弘、安藝翔、Kuntal Biswas、多久和典子、岡本安雄、多久和陽
- Organizer
  第88回日本生理学会ポスター
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] A novel Ca2+-and phosphoinositide 3-kinase-depend mechanism for myosin phosphatase inhibition and Ca2+-sensitization in vascular smooth muscle2011
- Author(s)
  Yoh Takuwa
- Organizer
  Winter workshop「Plenary Lecture」
- Place of Presentation
  光州(Gwanjn韓国)
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Role of Lysophospholipid Mediator Sphingosine-1-phosphate in Cardiac Fibrosis2011
- Author(s)
  Yoh Takuwa
- Organizer
  1st Meeting of Asian-Pacific Federation of Inflam mation and Regeneration and第32回日本日本炎症・再生医学会シンポジウム
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Data Source
  KAKENHI-PUBLICLY-23116509
[Presentation] ポリ乳酸-グリコール酸共重合体を基材としたスフィンゴシン-1-リン酸徐放微粒子製剤による持続性放出はマウス虚血肢においてAkt/ERK-eNOSを介して血管新生および血管成熟を促進し血流を回復させる2011
- Author(s)
  戚〓、岡本安雄、吉岡和晃、王飛、崔弘、Biswas Kuntal、安藝翔、Dandar Erdembileg、多久和典子、多久和陽
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスII型PI3キナーゼC2αの血管形成における生理的役割:コンディショナルKOマウスを用いた解析2010
- Author(s)
  吉岡和晃、吉田耕太朗、安藝翔、Kuntal Biswas、Wa Du、Xun Qi、Fei Wang、多久和典子、岡本安雄、多久和陽
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  日盛岡市民文化ホールいわて県民情報交流センター(岩手)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Development of Cardiac Fibrosis in Sphingosine Kinase 1 Transgenic Mice through an S1P3 Receptor-mediated Reactive Oxygen Species-dependent Process2010
- Author(s)
  Noriko Takuwa, Seiichiro Ohkura, Shinichiro Takashima, Keisuke Ohtani, Yasuo Okamoto, Soichiro Usui, Kazuaki Yoshioka, Masayuki Takamura, Shuichi Kaneko, Yoh Takuwa
- Organizer
  第74回日本循環器学会総会
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] S1P2受容体によるがん血管新生抑制とそのメカニズム2010
- Author(s)
  多久和典子、杜娃、吉岡和晃、岡本安雄、多久和陽
- Organizer
  日本脂質生化学会
- Place of Presentation
  森秋旅館(群馬伊香保)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Signaling of vascular smooth muscle contraction2010
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa.
- Organizer
  1st International Conference on Biorheology
- Place of Presentation
  和光市
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] クラスIIα型PI3キナーゼC2αは血管新生及びバリアー機能に必須である2010
- Author(s)
  吉岡和晃、多久和典子、岡本安雄、多久和陽
- Organizer
  第18回血管生物医学会
- Place of Presentation
  梅田スカイビル(大阪)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Sphingosine-1-phosphate receptor-2 inhibits tumor angiogenesis and tumor growth in vivo in mice Keystone Symposia Bioactive Lipids2010
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto, and Yoh Takuwa
- Organizer
  Biochemistry and Diseases
- Place of Presentation
  ウエステン都ホテル京都(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] スフィンゴシン-1-リン酸と血管新生の制御2010
- Author(s)
  多久和陽
- Organizer
  第43回加齢医学研究所シンポジウム
- Place of Presentation
  加齢医学研究所 (宮城県)
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] スフィンゴシン-1-リン酸と血管新生の制御2010
- Author(s)
  多久和陽
- Organizer
  第43回加齢医学研究所シンポジウム
- Place of Presentation
  加齢医学研究所大会議室(仙台)シンポジウム発表
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] スフィンゴシン-1-リン酸と血管新生の制御2010
- Author(s)
  多久和陽
- Organizer
  第43回加齢医学研究所シンポジウム
- Place of Presentation
  東北大学加齢医学研究所(仙台)
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] スフィンゴシン-1-リン酸と血管新生の制御2010
- Author(s)
  多久和陽
- Organizer
  第43回加齢医学研究所シンポジウム
- Place of Presentation
  加齢医学研究所(宮城県)
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] S1P2 IS AN ANGIOGENESIS-SUPPRESSIVE RECEPTOR2009
- Author(s)
  Yoh Takuwa
- Organizer
  International Conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  学術総合センター(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 腫瘍血管新生におけるスフィンゴシンー1-リン酸受容体S1P2の役割2009
- Author(s)
  Wa Du,多久和典子,吉岡和晃,岡本安雄, Xun Qi, Fei Wang, Hong Cui, Kuntal Biswas,杉原一司,浅野雅秀,多久和陽
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] INVOLVEMENT OF THE Ca2+-PI3K-C2ALPHARHO-MLC PHOSPHATASE PATHWAY IN HYPERTENSION2009
- Author(s)
  Yasuo Okamoto, Mohammed Ali Azam, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] マウス後肢虚血モデルにおける徐放化S1P製剤を用いた血管新生療法2009
- Author(s)
  戚〓、岡本安雄、村川智美、王飛、尾山治、吉岡和晃、杜娃、多久和典子、多久和陽
- Organizer
  第17回日本血管生物医学会
- Place of Presentation
  東京大学(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Atsusi Sato Noriko Takuwa The pathophysiolosical roles of phosphoinositide 3-kinase(PI3K) class II a-isoform, a Ca2+-dependent regulator of Rho in vascular smooth blood pressure regulation Post-Genomic Advances in the Physiology of Smooth2009
- Author(s)
  Yoh Takuwa, Kazuaki Yoshioka, Yasuo Okamoto Mohammed Ali Azam, Young Mi Seok
- Organizer
  Muscle Satellite Symposium of IUPS 2009
- Place of Presentation
  名古屋市立大学病院(名古屋)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 心筋リモデリングにおけるスフィンゴシン-1-リン酸情報伝達系の病態生理学的役割-スフィンゴシンキナーゼ1トランスジェニックマウスを用いた検討-2009
- Author(s)
  多久和典子,大倉誓一郎,高島伸一郎,大谷啓輔,薄井荘一郎,岡本安雄,王飛,杜娃,吉岡和晃,多久和陽
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] 血管平滑筋のシグナル伝達2009
- Author(s)
  多久和陽
- Organizer
  第24回日本ショック学会
- Place of Presentation
  金沢市文化ホール(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] S1P2 IS AN ANGIOGENESIS-SUPPRESSIVE RECEPTOR2009
- Author(s)
  多久和陽
- Organizer
  International Conference on Phospholipase A2 and Linid Mediators
- Place of Presentation
  学術総合センター(東京都)
- Year and Date
  2009-05-27
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] S1P2 IS AN ANGIOGENESIS-SUPPRESSIVE RECEPTOR International Conference on Phospholipase A2 and Lipid Mediators2009
- Author(s)
  Yoh Takuwa
- Place of Presentation
  National Center of Sciences(東京)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] 血管内皮細胞のTGFb1-Smadシグナル伝達系におけるクラスIIa型PI3キナーゼC2aの役割2009
- Author(s)
  安藝翔,吉岡和晃,岡本安雄,多久和陽
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂(金沢)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] RHOMLC PHOSPHATASE PATHWAY IN HYPERTENSION2009
- Author(s)
  Yasuo Okamoto, Mohammed Ali Azam, Kazuaki Yoshioka, Yoh Takuwa
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Masahide Asano and Yoh Takuwa HOST CELL S1P2 RECEPTOR NEGATIVELY REGULATES TUMOR GROWTH AND ANGIOGENESIS IN VIVO International Conference on Phospholipase A2 and Lipid Mediators2009
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto
- Place of Presentation
  National Center of Sciences(東京)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] HOST CELL S1P2 RECEPTOR NEGATIVELY REGULATES TUMOR GROWTH AND ANGIOGENESIS IN VIVO2009
- Author(s)
  Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto, Masahide Asano and Yoh Takuwa.
- Organizer
  International Conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  学術総合センター(東京)
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] S1P2 IS AN ANGIOGENESIS-SUPPRESSIVE RECEPTOR2009
- Author(s)
  多久和陽
- Organizer
  International Conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  学術総合センター (東京都)
- Year and Date
  2009-05-27
- Data Source
  KAKENHI-PROJECT-21390057
[Presentation] Sphingosine-1-phosphate signaling in tumor biology THE U.S. -JAPAN COOPERATIVE CANCER RESEARCH PROGRAM WORKSHOP2008
- Author(s)
  Yoh Takuwa, Wa Du, Noriko Takuwa, Kazuaki Yoshioka, Yasuo Okamoto
- Place of Presentation
  (平安会館)京都
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Sphingosine-1-phosphate signaling in tumor biology2008
- Author(s)
  Yoh Takuwa
- Organizer
  THE U.S.-JAPAN COOPERATIVE CANCER RESEARCH PROGRAM WORKSHOP 2008
- Place of Presentation
  京都
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] スフィンゴシンキナーゼ1a トランスジェニックマウスにおける心筋線維化の発症2007
- Author(s)
  多久和典子
- Organizer
  第80回日本生化学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Transgenic overexpression of sphingosine kinase la in mice provokes cardiac fibrosis but not increased spontaneous malignancy2007
- Author(s)
  Y. Takuwa
- Organizer
  3rd International Conference on Phospholopase A2 and Lipid Mediators
- Place of Presentation
  イタリア
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] 尾形悦郎癌悪液質モデルラットにおける視床下部摂食関連遺伝子発現とPTHrPの関与2007
- Author(s)
  上田陽一、橋本弘史、東由美子、小沼悦郎、岡部尚文、鈴木仁士、川崎展、藤原広明、多久和陽
- Organizer
  第80回日本内分泌学会東京国際フォーラム
- Place of Presentation
  東京
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Transgenic overexpression of sphingosine kinase 1a in mice provokes cardiac fibrosis but not increased spontaneous malignancy.2007
- Author(s)
  Y. Takuwa
- Organizer
  3ed International Cconference on Phospholopase A2 and Lipid Mediators Gland Hotel Vesuvio
- Place of Presentation
  イタリア
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Regulation of Akt activation and cell migration by Lysophosphatidic acid (LPA)2006
- Author(s)
  Naotoshi Sugimoto, Noriko Takuwa, Yoh Takuwa
- Organizer
  第20回国際生化学・分子生物学会議/第79回日本生化学会大会国立京都国際会館
- Place of Presentation
  京都宝ヶ池プリンスホテル(京都)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] S1P2受容体を介したB16メラノーマ細胞の制御2005
- Author(s)
  多久和典子, 杉本直俊, 尾山治, 多久和陽
- Organizer
  第82回日本生理学会大会
- Place of Presentation
  仙台国際センター(仙台)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Y. Lysophosphatidic acid (LPA) receptor LPA1/Edg2 generates both the stimulatory and inhibitory signals for Rac and cell migration.2005
- Author(s)
  Sugimoto. N, Takuwa. N, Takuwa
- Organizer
  International Union of Physiological Sciences 2005.
- Place of Presentation
  Pali Mountain, (アメリカ)
- Data Source
  KAKENHI-PROJECT-17014034
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Essential role of PI3K class II α for endosomal signaling of S1P1 and other receptors
- Author(s)
  Yoh Takuwa
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-02-10 – 2015-02-12
- Invited
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Sphingosine 1-phosphate receptor-2 plays a protective role against lipopolysaccharide (LPS)-induced acute lung injury
- Author(s)
  Yasuo Okamoto, Hong Cui, Kazuaki Yoshioka, Noriko Takuwa, Sho Aki, JuanJuan Zhao, Hoa Quynh Pham, Md. Azadul Kabir Sarker, Saori Koizumi, Yoh Takuwa
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県・神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Essential role of PI3K class II α for endosomal signaling of S1P1 and other receptors
- Author(s)
  Yoh Takuwa
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-02-10 – 2015-02-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF-1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府・東大阪市）
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF-1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] Essential role of PI3K class II α for endosomal signaling of S1P1 and other receptors
- Author(s)
  Yoh Takuwa
- Organizer
  6th international conference on Phospholipase A2 and Lipid Mediators
- Place of Presentation
  京王プラザホテル（東京都・新宿区）
- Year and Date
  2015-02-10 – 2015-02-12
- Invited
- Data Source
  KAKENHI-PROJECT-24390051
[Presentation] Sphingosine-1-phosphate receptor-2 (S1P2) negatively regulates eNOS and protects against acute vascular barrier disruption
- Author(s)
  Yasuo Okamoto, Cui Hong, Kazuaki Yoshioka, Noriko Takuwa, Toshishige Shibamoto, Yoh Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PUBLICLY-25116711
[Presentation] クラスIIα型PI3K-C2αはALK5 内在化及び足場タンパクSARA のエンドソームへの動員を制御しTGF-1-Smad2/3 を介した血管新生を調節する
- Author(s)
  安藝翔、吉岡和晃、岡本安雄、多久和典子、多久和陽
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2014-06-06 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25670162
[Presentation] Distinct role of S1P2 in the functional regulation of vascular endothelium and smooth muscle
- Author(s)
  Yoh Takuwa, Yasuo Okamoto, Kazuaki Yoshioka, Noriko Takuwa
- Organizer
  The 18th International Vascular Biology Meeting 2014 (IVBM 2014)
- Place of Presentation
  みやこめっせ
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116711

1. TAKUWA Noriko (70150290)

# of Collaborated Projects: 13 results

# of Collaborated Products: 165 results
2. YOSHIOKA Kazuaki (80333368)

# of Collaborated Projects: 10 results

# of Collaborated Products: 83 results
3. SUGIMOTO Naotoshi (80272954)

# of Collaborated Projects: 8 results

# of Collaborated Products: 33 results
4. MIYATA Tetsuro (70190791)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SAKURADA Sotara (00215691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OKAMOTO Yasuo (80293877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
7. 山下亀次郎 (80015982)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HAMADA Kyoko (20262024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAMADA Hirofumi (00189614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IMANISHI Hiroaki (60270881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAKI Tomio (10134561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KURIHARA Hideyuki (30261853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOHAMA Kazuhiro (30101116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Akio (60261856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NEGISHI Masatoshi (80272235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Iino Kenji (60595453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 眞崎智生 (60009991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 柳沢正史 (20202369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 木村定雄 (40134225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平田結喜緒 (50135787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 後藤勝年 (30012660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 村上和雄 (70110517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 井村裕夫 (10025570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 山下勝幸 (20183121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 井上和秀 (80124379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 古家喜四夫 (40132740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 桂木猛 (40004717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 森際克子 (00273665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 佐藤紀 (40170724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 竹村博文 (20242521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 真崎知生

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. ANGGARD E.E.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. LIPPTON H.L.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. SNYDER S.H.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KON V.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. REID J.J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. LUSCHER T.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. MAGUN B.U.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. HIGHSMITH R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. POLAK J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. DUNN M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. WARTON J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. SCOTTーBURDEN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. RYAN U.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. VANHOUTTE P.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. VANE J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. DAVENPORT A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. SCOTT Burden

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. WHARTON J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 川尻剛照

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 高倉伸幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 酒井佳夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 高村雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

takuwa yo 多久和 陽

TAKUWA Yoh 多久和 陽

多久 和陽 タクワ アキラ

多久和 陽 タクワ ヨウ

Research Projects

Research Products

Co-Researchers

Effects of perivascular tissue on endothelial function of internal thoracic artery in CABG

Principal Investigator

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Regulation of vascular cell function through control of membrane traffic by cellular lipid signalingPrincipal Investigator

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炎症制御因子としてのスフィンゴシン－１－リン酸の血管障害における役割Principal Investigator

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Control of vascular barrier integrity by MTM family of phosphatidylinositol 3-phosphate phosphatasePrincipal Investigator

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Mechanisms for the regulation of vascular homeostasis by functional lipid moleculesPrincipal Investigator

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炎症制御因子としてのスフィンゴシン－１－リン酸の血管障害における役割Principal Investigator

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Disruption of vascular integrity by deficiency of PI3K class II αisoform in micePrincipal Investigator

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Role of functionallipids in cardiovascular homeostasis and diseasesPrincipal Investigator

Principal Investigator

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Signaling for regulating hematogenous metastasis of tumorsPrincipal Investigator

Principal Investigator

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Interrated research on the physiological role ofbioactive sphingosine-1-phosphate and Edg receptors by using genetically engineered maice.Principal Investigator

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G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズムPrincipal Investigator

Principal Investigator

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G蛋白共役型受容体による癌の浸潤・転移の制御とその分子メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Molecular dissection of the physiological role of bioactive sphingosine-1-phosphate and Edg receptorsPrincipal Investigator

takuwa yo 多久和陽

TAKUWA Yoh 多久和陽

多久和陽タクワアキラ

多久和陽タクワヨウ