ISHIKAWA Toshihisa 石川智久

… Alternative Names

石川智久

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Researcher Number	60193281
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Affiliation (based on the past Project Information) *help	2013: 独立行政法人理化学研究所, ライフサイエンス技術基盤研究センター, 上級研究員 2012: 独立行政法人理化学研究所, LSA要素技術開発ユニット, 上級研究員 2011: 独立行政法人理化学研究所, ＬＳＡ要素技術開発ユニット, 上級研究員 2009: Tokyo Institute of Technology, オミックス基盤研究領域, 客員主管研究員 2007 – 2008: Tokyo Institute of Technology, 大学院・生命理工学研究科, 教授 … More 2005 – 2006: 東京工業大学, 大学院生命理工学研究科, 教授 2000 – 2004: 東京工業大学, 大学院・生命理工学研究科, 教授 1988: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 医薬分子機能学 / Tumor diagnosis / Applied pharmacology / Living organism molecular science Except Principal Investigator Neurosurgery / 代謝生物化学 / 医薬分子機能学
Keywords	Principal Investigator トランスポーター / Protein Kinase / Canser Drug Resistance / Structure-Activity Relationship / Protein Phosphatase / High Speed Screening / ABC Transporter / Genome-Based Drug Discovery / ゲノム / カーバメートライブラリー … More / カンタリジン / 光学活性 / プロテインキナーゼ / 制癌剤 / 構造活性相関 / プロテインホスファターゼ / 高速スクリーニング系 / ABCトランスポーター / ゲノム創薬 / 臨床応用 / バイオマーカー / 転写制御 / 光線力学診断法 / 代謝 / 遺伝子発現 / メタボローム解析 / アミノレブリン酸 / 脳腫瘍 / 癌幹細胞 / 5-アミノレブリン酸( ALA) / Nrf2 / ABCG2 / ポルフィリン / 5-アミノレブリン酸(ALA) / 光線力学治療 / 光線力学診断 / 悪性脳腫瘍 / 翻訳後修飾 / 遺伝子多型 / 糖鎖 / タンパク質 / 分子プローブ / 創薬 / 生理活性 / 脳・神経 / 癌 … More Except Principal Investigator 脳腫瘍 / 腫瘍可視化 / ポルフィリン / 光線力学療法 / ５アミノレブリン酸 / 悪性神経膠腫 / 光線力学診断 / active site liganding loop / glycation / Werner症候群 / グリケーション / 悪性リンパ腫 / 5アミノレブリン酸 / 手術ロボット / ５－アミノレブリン酸 / プロトポルフィリンIX / がん幹細胞 / ABCG2 / 分子デザイン / 5－アミノレブリン酸 / 光線力学治療 / retinopathy / Enzyme-linked immunosorbent Assay / Cu,Zn-SOD / superoxide dismutase / 不活性化 / スーパーオキサイドディスムターゼ / グリシト-ルリジン / Enzyme-linked Immunosorbent Assay / 網膜症 / Enzyme-linked Immnosorbent Aassay法 / ス-パ-オキサイドディスムタ-ゼ(SOD) / membrane transporter / drug screening / brain capillary endothelial cells / conditionally immortalized cell line / culture cell / gene expression / plasma membrane / blood-brain barrier / 輸送担体 / 新薬スクリーニング / 脳毛細血管内皮細胞 / 条件的不死化細胞 / 培養細胞 / 遺伝子発現系 / 細胞膜輸送 / 血液脳関門 / スーパーオキサイドデイスムターゼ / DNAチップ / アロディニア / PGE_2 / リアノジン受容体 / 15R-TIC / リピドA / サリドマイド / Cu-ATSM / ダントロレン誘導体 / 4'-チオリボヌクレオシド / 可視化プローブ / RXRアンタゴニスト / プロスグランジン / 34mCl / キナーゼ阻害剤 / レチノイド / 光親和性標識法 / MicroPET / プラナーポジトロンイメージング / 神経性疼痛 / Socius / ABCトランスポーター / non-RI光親和性標識法 / 3成分連結PG合成法 / シグナル解析 / 神経因性疼痛 / 阻害剤 / キナーゼ / 人工核酸 / 蛍光プローブ / 高速メチル化 / PET Less

Innovation of 5-ALA photodynamic diagnosis and treatment in malignant glioma by drug discovery and molecular design
- Principal Investigator
  
  Kuroiwa Toshihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical College
Development of equipment for next generation 5-ALA photodynamic diagnosis and treatment
- Principal Investigator
  
  Kajimoto Yoshinaga
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical College
Photodynamic diagnosis of malignant brain tumor: analysis of molecular mechanisms and application to clinical diagnosisPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Toshihisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnosis
- Research Institution
  The Institute of Physical and Chemical Research
ヒトABCトランスポーターの遺伝子多型を認識するタンパク品質管理機構の解明Principal Investigator
- Principal Investigator
  
  石川智久
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  The Institute of Physical and Chemical Research
  Tokyo Institute of Technology
Chemical biology targeting the brain : Molecular design of anticancer agents that efficiently attack brain tumorsPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Toshihisa
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo Institute of Technology
DRUG MOLECULAR DESIGN BASED ON THE FUNCTIONAL ANALYSIS OF DRUG TRANSPORTERSPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Toshihisa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tokyo Institute of Technology
生物新機能と創薬をめざす生体内分子科学
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Gifu University
Development of new drug screening system using the blood-brain barrier transporter gene expression
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tohoku University
癌化におけるスーパーオキサイドの役割
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Inactivation of Cu,Zn-superoxide dismutase due to glycation
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University Medical School

[Book] Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013
- Author(s)
  Ishikawa T, Konig J, Kim R. (本の編集)
- Total Pages
  480
- Publisher
  John-Willey & Sons, Hoboken, NJ, USA
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Human ABC Transporter ABCC11. Ishikawa T, Konig J, Kim R. (eds.), Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013
- Author(s)
  Ishikawa T, Toyoda Y
- Publisher
  John-Willey & Sons
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Emerging new technology of SNP typing. Ishikawa T, Konig J, Kim R. (eds.), Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013
- Author(s)
  Ishikawa T, Hayashizaki Y
- Publisher
  John-Willey & Sons
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Pharmacogenomics of Human Drug Transporters: Clinical Impacts2013
- Author(s)
  Ishikawa T, Kim R., Konig J, (編集)
- Total Pages
  433
- Publisher
  John-Welley & Sons, Hoboken, NJ, USA
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Future perspectives. Ishikawa T, Konig J, Kim R. (eds.), Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013
- Author(s)
  Ishikawa T, Ware J
- Publisher
  John-Willey & Sons
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Pharmacogenomics of Human Drug Transporters: Clinical Impacts2013
- Author(s)
  Ishikawa T, Kim RB, Koenig J.
- Total Pages
  422
- Publisher
  Wiley, Hoboken, NJ, USA
- Data Source
  KAKENHI-PROJECT-23650619
[Book] Recent advances in pharmacogenomic technology for personalized medicine. In : Drug Metabolism2011
- Author(s)
  Ishikawa T, Hayashizaki Y
- Publisher
  InTech Open Access Publisher
- Data Source
  KAKENHI-PROJECT-23650619
[Book] MRP1 (ABCC1)「薬物トランスポーター活用ライブラリー機能・輸送基質から創薬・臨床応用まで」(乾賢一・編)2009
- Author(s)
  石川智久
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18201041
[Book] 小児科診療2009
- Author(s)
  石川智久, 中村亮太, 侵井亜季
- Publisher
  株式会社診断と治療社
- Data Source
  KAKENHI-PROJECT-18201041
[Book] 小児科診療2009
- Author(s)
  石川智久, 中村亮太, 櫻井亜季
- Publisher
  株式会社診断と治療社
- Data Source
  KAKENHI-PROJECT-19659136
[Book] ポルフィリン(ポルフィリンの光励起によるヒトABCトランスポーターABCG2とヘムオキシゲナーゼの誘導におけるNrf2の役割)2009
- Author(s)
  萩谷祐一郎、足立達彦、小倉俊一郎、安然、田村藍、中川大、望月徹、石川智久
- Data Source
  KAKENHI-PROJECT-18201041
[Book] バイオ医薬の開発技術とシーズ2009
- Author(s)
  斉藤光, 石川智久
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19659136
[Book] 創薬スクリーニング:発現系の構築から創薬への応用「薬物トランスポーター活用ライブラリー機能・輸送基質から創薬・臨床応用まで」(乾賢一・編)2009
- Author(s)
  石川智久
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18201041
[Book] 小児科診療2009
- Author(s)
  石川智久、中村亮太、櫻井亜季
- Publisher
  株式会社診断と治療社
- Data Source
  KAKENHI-PROJECT-18201041
[Book] バイオ医薬の開発技術とシース2009
- Author(s)
  斉藤光, 石川智久
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-18201041
[Book] プロテインキナーゼとABCトランスポーターを標的とした分子標的医薬の開発とその戦略「バイオ医薬の開発技術とシーズ」山本重夫監修2008
- Author(s)
  齊藤光、石川智久
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-18201041
[Book] バイオ医薬の開発技術とシーズ2008
- Author(s)
  齊藤光、石川智久
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-18201041
[Book] トランスポーター研究最前線2008
- Author(s)
  田村藍, 若林香菜子, 齊藤光, 石川智久
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-19659136
[Book] トランスポーター科学最前線2008
- Author(s)
  辻彰, 田村藍, 若林香奈子, 齊藤光, 石川智久, 他28名
- Total Pages
  374
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-18201041
[Book] トランスポーター科学最前線2008
- Author(s)
  辻彰, 田村藍, 若林香奈子, 齊藤光, 石川智久, 他28名
- Total Pages
  374
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-19659136
[Book] トランスポーター研究最前線2008
- Author(s)
  田村藍、若林香菜子、齊藤光、石川智久
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-18201041
[Book] トランスポーター研究最前線2008
- Author(s)
  田村藍, 若林香菜子, 齊藤光, 石川智久
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-18201041
[Book] ゲノム医学2004
- Author(s)
  石川智久(企画)
- Publisher
  メディカルレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Genomic Medicine2004
- Author(s)
  Ishikawa, T.(Editor)
- Publisher
  Medical Review Co.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] ゲノムと疾患2004
- Author(s)
  石川智久
- Publisher
  南山堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Genome and Diseases2004
- Author(s)
  Ishikawa, T.
- Publisher
  Nanzan-do
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] ゲノム創薬と未来産業2003
- Author(s)
  石川智久
- Total Pages
  94
- Publisher
  エルゼビア・ジャパン
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Genome Drug Discovery and Future Industry2003
- Author(s)
  Ishikawa, T.
- Total Pages
  94
- Publisher
  Elsevier-Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] ファーマコゲノミクス:21世紀のゲノム創薬と個の医療2002
- Author(s)
  石川智久(監訳)
- Total Pages
  434
- Publisher
  テクノミック
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Introduction to Drug Discovery Science : Paradigm Shift toward Post-Genome Era2002
- Author(s)
  Tsuji, A., Ishikawa, T.
- Publisher
  Kyoritsu
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Genome-based Drug Discovery in the Next Generation2002
- Author(s)
  Ishikawa, T.
- Publisher
  Nakayama Shoten
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] Pharmacogenomics : Drug Discovery and Personalized Medicine in the 21st Century2002
- Author(s)
  Ishikawa, T(Translation)
- Total Pages
  434
- Publisher
  Technomic
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] 次世代ゲノム創薬2002
- Author(s)
  石川智久
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] 創薬サイエンス入門:ポストゲノム時代へのパラダイムシフト2002
- Author(s)
  辻彰, 石川智久
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Book] 天然物及び食品添加物による細胞内レドックス制御機構の温故知新
- Author(s)
  足立達彦、萩谷祐一郎、中川大、石川智久
- Publisher
  Foods & Food Ingredients Jounal of Japan
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Inhibition of human ABC transporter ABCG2 by gefitinib to enhance the efficacy of ALA-photodynamic therapy of brain tumor: learning from in vitro and in vivo experiments.2014
- Author(s)
  Inoue Y, Ikegami Y, Kajimoto Y, Kuroiwa T, Ishikawa T.
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: 1 Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Gefitinb Enhances the Antitumor Activity of CPT-11 in vitro and in vivo by Inhibiting ABCG2 but not ABCB12013
- Author(s)
  Inoue Y, Ikegami Y, Sano K, Suzuki T, Yoshida H, Nakamura Y, Nakagawa H, Ishikawa T.
- Journal Title
  
  Chemotherapy
  
  Volume: 59 Issue: 4 Pages: 260-271
- DOI
  10.1159/000357772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Role of Nrf2 in cancer photodynamic therapy: regulation of human ABC transporter ABCG22013
- Author(s)
  Ishikawa Toshihisa, Kajimoto Yoshinaga, Sun Wei, Nakagawa Hiroshi, Inoue Yoji, Ikegami Yutaka, Miyatake Shin-Ichi, Kuroiwa Toshihiko
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 102 Issue: 9 Pages: 3058-3069
- DOI
  10.1002/jps.23563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592147, KAKENHI-PROJECT-23650619
[Journal Article] Gefitinib enhances the efficacy of photodynamic therapy using 5-aminolevulinic acid in malignant brain tumor cells.2013
- Author(s)
  Sun Wei
- Journal Title
  
  Photodiagnosis Photodyn Ther
  
  Volume: 10 Issue: 1 Pages: 42-50
- DOI
  10.1016/j.pdpdt.2012.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390355, KAKENHI-PROJECT-23592147, KAKENHI-PROJECT-23650619, KAKENHI-PROJECT-24659658
[Journal Article] Inhibition of human ABC transporter ABCG2 by gefitinib to enhanc e the efficacy of ALA-photodynamic thera py of brain tumor : learning from in vitro and in vivo experiments2013
- Author(s)
  Inoue Y, Ikegami Y, Kajimoto Y, Kuroiwa T, Ishikawa T
- Journal Title
  
  ALA-Porphyrin Science
  
  Volume: vol.1 Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Clinical SNP detection by SmartAmp method.2013
- Author(s)
  Ishikawa T, Hayashizaki Y.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1015 Pages: 55-69
- DOI
  10.1007/978-1-62703-435-7_3
- ISBN
  9781627034340, 9781627034357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro2012
- Author(s)
  Hagiya Y, Endo Y, Yonemura Y, Takahashi K, Ishizuka M, Abe F, Tanaka T, Okura I, Nakajima M, Ishikawa T, Ogura S
- Journal Title
  
  Photodiagnosis Photodyn Ther
  
  Volume: 9(3) Issue: 3 Pages: 204-214
- DOI
  10.1016/j.pdpdt.2011.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501305, KAKENHI-PROJECT-23650619
[Journal Article] Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: the mechanism underlying 5-ALA-induced fluorescence in photodynamic diagnosis2011
- Author(s)
  Takahashi K, Ikeda N, Nonoguchi N, Kajimoto Y, Miyatake S, Hagiya Y, Ogura S, Nakagawa H, Ishikawa T, Kuroiwa T.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 13 Pages: 1234-1243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2011
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Miyatake S, Kuroiwa T
- Journal Title
  
  Pharmaceutics
  
  Volume: vol.2 Pages: 615-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors.2011
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Miyatake S, Kuroiwa T.
- Journal Title
  
  Pharmaceutics
  
  Volume: 3 Pages: 615-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650619
[Journal Article] Key role of human ABC transporter ABCG2 in photodynamic therapy and photodynamic diagnosis.2010
- Author(s)
  Ishikawa T, Nakagawa H, Hagiya Y, Nonoguchi N, Miyatake S, Kuroiwa T
- Journal Title
  
  Adv. Pharm. Sci. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Emerging new technologies in pharmacogenomics : Rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1(P-gp/MDR1)2010
- Author(s)
  Ishikawa T., Sakurai A, Hirano H, Lezhava A, Sakurai M, Hayashizaki Y
- Journal Title
  
  Pharmacology and Therapeutics (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Key role of human ABC transporter ABCG2 in photodynamic therapy and photodynamic diagnosis2010
- Author(s)
  Ishikawa T, Nakagawa H, Hagiya Y, Nonoguchi N, Miyatake S, Kuroiwa T.
- Journal Title
  
  Advances in Pharmacological Sciences (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Emerging new technology : QSAR analysis and MO calculation to characterize the interaction of protein kinase inhibitors with human ABC tran sporter ABCG2(BCRP)2010
- Author(s)
  Saito H, An R, Hirano H., Ishikawa T.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] QSAR analysis and MO calculation to predict drug interactions with human ABC transporter ABCG2.2010
- Author(s)
  Saito H, Ishikawa T
- Journal Title
  
  Current Trends Med. Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the F1p recombinase system2010
- Author(s)
  Wakabayashi-Nakao K, Tamura A, Koshiba S, Nakagawa H, Ishikawa T.
- Journal Title
  
  Methods in Molecular Biology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] QSAR analysis and MO calculation to predict drug interactions with human ABC transporter ABCG22010
- Author(s)
  Saito H, Ishikawa T.
- Journal Title
  
  Current Trends in Medicinal Chemistry (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Emerging new technologies in pharmacogenomics: Rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).2010
- Author(s)
  Ishikawa T., Sakurai A, Hirano H, Lezhava A, Sakurai M, Hayashizaki Y
- Journal Title
  
  Pharmacol. Ther. 126
  
  Pages: 69-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Emerging new technology: QSAR analysis and MO calculation to characterize the interaction of protein kinase inhibitors with human ABC transporter ABCG2 (BCRP).2010
- Author(s)
  Saito H, An R, Hirano H, Ishikawa T
- Journal Title
  
  Drug Metab. Pharmacokin. 25
  
  Pages: 72-83
- NAID
  10027581955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Quality control of human ABCG2 protein in the endoplasmic reticulm : ubiquitination and proteasomal degradation2009
- Author(s)
  Wakabayashi K, Tamura A, Furukawa T, Nakagawa H, Ishikawa T.
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flprecombinase system2009
- Author(s)
  Wakabayashi-Nakao K, Tamura A, Koshiba H, Nakagawa H, Ishikawa T.
- Journal Title
  
  Methods Mol. Biol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article]2009
- Author(s)
  石川智久
- Journal Title
  
  薬物トランスポーター活用ライブラリー(乾賢一・編)(羊土社)
  
  Pages: 158-163
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] A rapid and cost-effective SNP detection method : Application of SmartAmp2 to pharmacogenomics research2009
- Author(s)
  Mitani Y, Lezhava A, Sakurai A, Horikawa A, Nagakura M, Hayashizaki Y, Ishikawa T.
- Journal Title
  
  Pharmacogenomics (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] 天然物及び食品添加物による細胞内レドツクス制御機構の温故知新2009
- Author(s)
  足立達彦, 萩谷祐一郎, 中川大, 石川智久
- Journal Title
  
  Foods & Food Ingredients Journal of Japan. 214 (1)
  
  Pages: 35-47
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Major SNP(Q141K)variant of human ABC transporter ABCG2 undergoes lysosomal and proteosomal degradations2009
- Author(s)
  Furukawa T, Wakabayashi K, Tamura A, Nakagawa H, Morishima Y, Osawa Y, Ishikawa T.
- Journal Title
  
  Pharmaceutical Research 26
  
  Pages: 469-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] 天然物及び食品添加物による細胞内レドックス制御機構の温故知新2009
- Author(s)
  足立達彦、萩谷祐一郎、中川大、石川智久
- Journal Title
  
  Foods Food Ingredients Jounal of Japan 214
  
  Pages: 35-47
- NAID
  40016462151
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Earwax, osmidrosis, and breast cancer why does one SNP(538G>A) in the human ABC transporter ABCC11 gene determine earwax type?2009
- Author(s)
  Toyoda Y, Sakurai A, Mitani Y, Nakashima M, Yoshiura K, Nakagawa H, Sakai Y, Ota I, Lezhava A, Hayashizaki Y, Niikawa N, Ishikawa T.
- Journal Title
  
  FASEB Journal 23
  
  Pages: 2001-2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Role of Nrf2 in the induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells via photoactivation of porphyrins2009
- Author(s)
  Hagiya Y, Adachi T, Okura S, An R, Tamura A, Nakagawa H, Mochizuki T, Ishikawa T.
- Journal Title
  
  PORPHYRINS 8
  
  Pages: 12-18
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Quality control of human ABCG2 protein in the endoplasmic reticulm : ubiquitination and proteasomal degradation2009
- Author(s)
  Wakabayashi K, Tamura A, Furukawa T, Nakagawa H, Ishikawa T.
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Technical pitfalls and improvements in high-speed screening and QSAR analysis to predict durg-drug interactions of ABC transporter ABCB11(bile salt export pump)2009
- Author(s)
  Saito H, Hirano H, Wangsoo Shin, Nakamura R, Osumi M, Ishikawa T.
- Journal Title
  
  AAPS Journal 11
  
  Pages: 581-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Technical pitfalls and improvements in high-speed screening and QSAR analysis to predict drug-drug interactions of ABC transporter ABCB11 (bile salt export pump).2009
- Author(s)
  Saito H, Hirano H, Wangsoo Shin, Nakamura R, Osumi M, Ishikawa T
- Journal Title
  
  AAPS J 11(3)
  
  Pages: 581-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] The role of human ABC transporter ABCG2 (BCRP)in pharmacotherapy2009
- Author(s)
  Ishikawa T.
- Journal Title
  
  Advanced Drug Delivery Reviews 61(1)
  
  Pages: 1-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] 薬物トランスポーターのSNP診断2009
- Author(s)
  石川智久
- Journal Title
  
  MedicalBio 別冊(7月)
  
  Pages: 78-83
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] High-speed xcreening and QSAR analysis to predict durg-drug interactions of ABC transporter ABCB11 (bile salt export pump)2009
- Author(s)
  Saito H, Hirano H, Nakamura R, Ishikawa T.
- Journal Title
  
  AAPS J (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro2009
- Author(s)
  An R、Hagiya Y、Tamura A、Li S、Saito H、Tokushima D、Ishikawa T
- Journal Title
  
  Pharmaceutical Research 26(2)
  
  Pages: 449-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro.2009
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Tokushima D, Ishikawa T
- Journal Title
  
  Pharm Res 26(2)
  
  Pages: 449-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Major SNP (Q141K)variant of human ABC transporter ABCG2 Undergoes lysosomal and proteosomal degradations2009
- Author(s)
  Furukawa T, Wakabayashi K, Tamura A, Nakagawa H, Morishima Y, Osawa Y, Ishikawa T
- Journal Title
  
  Pharmaceutical Research 26(2)
  
  Pages: 469-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of human ATP-binding cassette transporter ABCG22009
- Author(s)
  Nakagawa H, Wakabayashi-Nakao K, Tamura A, Toyoda Y, Koshiba S, Ishikawa T.
- Journal Title
  
  FEBS Journal 276
  
  Pages: 7237-7252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro2009
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Ishikawa T.
- Journal Title
  
  PORPHYRINS 8
  
  Pages: 7-12
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] High-speed xcreening and QSAR analysis to predict durg-drug interactions of ABC transporter ABCB11(bile salt export pump)2009
- Author(s)
  齊藤光、平野弘之、中村亮太、石川智久
- Journal Title
  
  AAPS J (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article]2009
- Author(s)
  石川智久
- Journal Title
  
  薬物トランスポーター活用ライブラリー(乾賢一・編)(羊土社)
  
  Pages: 136-139
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin- dependent kinase inhibitors in vitro2009
- Author(s)
  An R, Hagiya Y, Tamura A, Li s, Saito H, Tokushima D, Ishikawa T.
- Journal Title
  
  Pharmaceutical Research 26 (2)
  
  Pages: 449-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Transport-metabolism interplay : LXRa-mediated induction of human ABC transporter ABCC2(cMOAT/MRP2)in HepG2 cells2009
- Author(s)
  Adachi T, Nakagawa H, Hagiya H, Yasuoka T, Ishikawa T.
- Journal Title
  
  Molecular Pharmaceutics 6
  
  Pages: 1678-1688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro2009
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Tokushima D, Ishikawa T.
- Journal Title
  
  Pharmaceutical Research 26
  
  Pages: 449-458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] A rapid and cost-effective SNP detection method : Application of SmartAmp2 to pharmacogenomics research2009
- Author(s)
  Mitani Y, Lezhava A, Sakurai A, Horikawa A, Nagakura M, Hayashizaki Y, Ishikawa T.
- Journal Title
  
  Pharmacogenomics (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Emerging Trends in Human ABC Transporters2009
- Author(s)
  Ishikawa T.
- Journal Title
  
  Pharmaceutical Research 26(2)
  
  Pages: 445-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] 個別化医療」の市場とわが国における課題克服2009
- Author(s)
  石川智久
- Journal Title
  
  MedicalBio 別冊(7月)
  
  Pages: 24-31
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Emerging Trends in Human ABC Transporters2009
- Author(s)
  Ishikawa T.
- Journal Title
  
  Pharmaceutical Research 26(2)
  
  Pages: 445-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Quality control of human ABCG2 protein in the endoplasmeic reticulm : ubiquitination and proteasomal degradation2009
- Author(s)
  Wakabayashi-Nakao K, Tamura A, Furukawa T, Nakagawa H, Ishikawa T.
- Journal Title
  
  Advances in Drug Delivery Review 61
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Nrf 2-dependent induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells by photoactivation of porphyrins : Biochemical implications for cancer cell response to photodynamic therapy2008
- Author(s)
  Hagiya Y, Adachi T, Ogura S, An R, Tamura A, Nakagawa H, Okura I, Mochizuki T, Ishikawa T.
- Journal Title
  
  Journal of Experimental Therapeutics and Oncology 7
  
  Pages: 153-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] MRP class of human ABC transporters: Role of glutathione in the function and gene regulation.2008
- Author(s)
  Toyoda Y, Hagiya Y, Adachi T, Hoshijima K, Kuo MT, Ishikawa T.
- Journal Title
  
  Xenobiotica (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro.2008
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Tokushima D, and Ishikawa T.
- Journal Title
  
  Photochem. Photobiol. Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Human ABC transporters ABCG2 (BCRP)and ABCG42008
- Author(s)
  Koshiba S, An R, Saito H, Wakabayashi K, Tamura A. Ishikawa T.
- Journal Title
  
  Xenobiotica 38(7-8)
  
  Pages: 863-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro.2008
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Tokushima D, and Ishikawa T.
- Journal Title
  
  Photochem. Photobiol. Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Unibiquitin-mediated proteasomal degradation of nonsynonymous SNP variants of human ABC transporter ABCG2.2008
- Author(s)
  Nakagawa H, Tamura A, Wakabayashi K, Hoshijima K, Komada M, Yoshida T, Kometani S, Matsubara T, Mikuriya K, 'Ishikawa T.
- Journal Title
  
  Biochem. J. 411
  
  Pages: 623-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] ポルフィリンの光励起によるヒトABCトランスポーターABCG2とヘムオキシゲナーゼの誘導におけるNrf2の役割2008
- Author(s)
  萩谷祐一郎, 足立達彦, 小倉俊一郎, 安然, 田村藍, 中川大, 望月徹, 石川智久
- Journal Title
  
  Porphyrins (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] 光毒性スクリーニングの最新手法2008
- Author(s)
  田村藍, 安然, 古川朋佳, 石川智久
- Journal Title
  
  谷本学校毒性質問箱 11
  
  Pages: 152-162
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Human ABC transporters ABCG2 (BCRP) and ABCG4.2008
- Author(s)
  Koshiba S, An R, Saito H, Wakabayashi K, Tamura A, and Ishikawa T.
- Journal Title
  
  Xenobiotica, (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] MRP class of human ABC transporters: Role of glutathione in the function and gene regulation.2008
- Author(s)
  Toyoda Y, Hagiya Y, Adachi T, Hoshijima K, Kuo MT, Ishikawa T.
- Journal Title
  
  Xenobiotica (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Nrf2-dependent induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells by photoactivation of porphyrins: Biochemical implications for cancer cell response to photodynamic therapy.2008
- Author(s)
  Hagiya Y, Adachi T, Ogura S, An R, Tamura A, Nakagawa H, Okura I, Mochizuki T, Ishikawa T
- Journal Title
  
  J. Exp. Ther. Oncol 7
  
  Pages: 153-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Nrf2-dependent induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells by photo activation of porphyrins: Biochemical implications for cancer cell response to photodynamic therapy2008
- Author(s)
  萩谷祐一郎、足立達彦、小倉俊一郎、安然、田村藍、中川大、望月徹、石川智久
- Journal Title
  
  Journal of Experimental Therapeutics and Oncology 7
  
  Pages: 153-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Unibiquitin-mediated proteasomal degradation of nonsynonymous SNP variants of human ABC transporter ABCG2.2008
- Author(s)
  Nakagawa H, Tamura A, Wakabayashi K, Hoshijima K, Komada M, Yoshida T, Kometani S, Matsubara T, Mikuriya K, Ishikawa T.
- Journal Title
  
  Biochem. J. 411
  
  Pages: 623-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: Development of in vitro high-speed screening systems.2008
- Author(s)
  Tamura A, An R, Hagiya Y, Hoshijima K, Yoshida T, Mikuriya K, and Ishikawa T.
- Journal Title
  
  Expert Opinion on Drug Metabolism and Toxicology 4(3)
  
  Pages: 255-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] ポルフィリンの光励起によるヒトABCトランスポーターABCG2とヘムオキシゲナーゼの誘導におけるNrf2の役割2008
- Author(s)
  萩谷祐一郎, 足立達彦, 小倉俊一郎, 安然, 田村藍, 中川大, 望月徹, 石川智久
- Journal Title
  
  Porphyrins (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Human ABC transporters ABCG2 (BCRP) and ABCG4.2008
- Author(s)
  Koshiba S, An R, Saito H, Wakabayashi K, Tamura A, and Ishikawa T.
- Journal Title
  
  Xenobiotica (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Drug-induced phototoxicity evoked by inhibition of human ABC transporter ABCG2: Development of in vitro high-speed screening systems.2008
- Author(s)
  Tamura A, An R, Hagiya Y, Hoshijima K, Yoshida T, Mikuriya K, and Ishikawa T.
- Journal Title
  
  Expert Opinion on Drug Metabolism and Toxicology 4(3)
  
  Pages: 255-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Human ABC transporters ABCG2 (BCRP)and ABCG42008
- Author(s)
  Koshiba S, An R, Saito H, Wakabayashi K, Tamura A, Ishikawa T.
- Journal Title
  
  Xenobiotica 38(7-8)
  
  Pages: 863-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases.2007
- Author(s)
  Nakamura T, Nozu K, Iijima K, Yoshikawa N, Moriya Y, Yamamori M, Kako A, Matsuo M, Sakurai A, Okamura N, Ishikawa T, Okumura K, Sakaeda T.
- Journal Title
  
  Biol. Pharm. Bull. 30(12)
  
  Pages: 2371-2375
- NAID
  110006546441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Prediction of drug-induced intrahepatic cholestasis : in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.2007
- Author(s)
  Sakurai A, Kurata A, Onishi Y, Hirano H, Ishikawa T.
- Journal Title
  
  Expert Opin. Drug Saf. 6・1
  
  Pages: 71-86
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Quantitative SAR analysis and molecular dynamics simulation to functionally validate nonsynonymous polylnorphisms of human ABC transporter ABCB1.2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M, Ishikawa T.
- Journal Title
  
  Biochemistry (in press)
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases.2007
- Author(s)
  Nakamura T, Nozu K. Iijima K, Yoshikawa N, Moriya Y, Yamamori M, Kako A, Matsuo M, Sakurai A, Okamura N, Ishikawa T, Okumura K, Sakaeda T.
- Journal Title
  
  Biol. Pharm. Bull. 30(12)
  
  Pages: 2371-2375
- NAID
  110006546441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Nrf2-dependent and-independent induction of ABC transporters ABCC1,ABCC2,and ABCG2 in HepG2 cells under oxidative strees.2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Hagiya Y, Hoshijima K, Noguchi N, Kuo MT and Ishikawa, T.
- Journal Title
  
  J. Exp. Ther. Oncol. 6
  
  Pages: 335-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Theoretical studies for molecular modeling of new camptothecin analogues.2007
- Author(s)
  Aida-Hyugaji S, Nakagawa H, Nomura J, Sakurai M, Nagashima U and Ishikawa T.
- Journal Title
  
  Croatica Chemica Acta 80(2)
  
  Pages: 277-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative strees.2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Hagiya Y, Hoshijima K, Noguchi N, Kuo MT and Ishikawa, T.
- Journal Title
  
  J. Exp. Ther. Oncol. 6
  
  Pages: 335-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Development of polyclonal antibodies specific to ATP-binding casstte transporters human ABCG4 and mouse Abcg4: site-specific expression of mouse Abcg4 in brain.2007
- Author(s)
  Koshiba S, Ito T, Shiota A, Wakabayashi K, Ueda M, Ichinose H, and Ishikawa T.
- Journal Title
  
  J. Exp. Ther. Oncol. 6
  
  Pages: 321-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Intramolecular disulfide bond is a critical checkpoint determining degradative fates of ABC transporter ABCG2 protein.2007
- Author(s)
  Wakabayashi K, Nakagawa H, Tamura A, Koshiba S, Hoshijima K, Komada M, and Ishikawa T.
- Journal Title
  
  J. Biol. Chem. 282(38)
  
  Pages: 27841-27846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Theoretical Studies for Molecular Modeling of New Camptothecin Analogues. Croat.2007
- Author(s)
  Aida-Hyugaji, S., Nakagawa, H., Nomura, J., Sakurai, M., Nagashima, U., Ishikawa, T
- Journal Title
  
  Chemica. Acta 80(2)
  
  Pages: 277-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] High-speed screening and quantitative SAR analysis of human ABC transporter ABCG2 for molecular modeling of anticancer drugs to circumvent multidrug resistance.2007
- Author(s)
  Saito H, Hirano H and Ishikawa T.
- Journal Title
  
  Mini Rev. Medcin. Chem. 7
  
  Pages: 1009-1018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] High-speed screening and quantitative SAR analysis of human ABC transporter ABCG2 for molecular modeling of anticancer drugs to circumvent multidrug resistance.2007
- Author(s)
  Saito H, Hirano H and Ishikawa T.
- Journal Title
  
  Mini Rev. Medcin. Chem. 7
  
  Pages: 1009-1018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Multidrug resistance-associated protein 9 (ABCC12) is present in sperm.2007
- Author(s)
  Ono N, van der Heiden I, Schffer GL, van de Wetering, van Deenter E, de Haas M, Boerke A, Gadella BM, de Rooij DG, Neefjes JJ, Groothuis TAM, Oomen L, Brocks L, Ishikawa T, and Borst P.
- Journal Title
  
  Biochem. J. 406(1)
  
  Pages: 31-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Re-evaluation and functional classification of nonsynonymous single nucleotide polymorphisms of human ABC transporter ABCG2.2007
- Author(s)
  Tamura A, Wakabayashi K, Onishi Y, Takeda M, Ikegami Y, Sawada S, Tsuji M, Matsuda Y and Ishikawa T.
- Journal Title
  
  Cancer Sci. 98(2)
  
  Pages: 231-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.2007
- Author(s)
  Sakurai A, Kurata A, Onishi Y, Hirano H and Ishikawa T.
- Journal Title
  
  Expert Opin. Drug Saf. 6(1)
  
  Pages: 71-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Quantitative SAR analysis and molecular dynamic simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1.2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M, Ishikawa T
- Journal Title
  
  Biochemistry 46(26)
  
  Pages: 7678-7693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture.2007
- Author(s)
  Nakagawa H, Hasumi K, Takami M, Aida-Hyugaji S, Woo JT, Nagai K, Ishikawa T and Wachi M.
- Journal Title
  
  Biochem. Pharmacol. 73(1)
  
  Pages: 34-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Intramolecular disulfide bond is a critical checkpoint determining degradative fates of ABC transporter ABCG2 protein.2007
- Author(s)
  Wakabayashi K, Nakagawa H, Tamura A, Koshiba S, Hoshijima K, Komada M, and Ishikawa T.
- Journal Title
  
  J. Biol. Chem. 282(38)
  
  Pages: 27841-27846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Re-evaluation and functional classification of nonsynonymous single nucleotide polymoiphisms of human ABC transporter ABCG2.2007
- Author(s)
  Tamura A, Wakabayashi K, Onishi Y, Takeda M, Ikegami Y, Sawada S, Tsuji M, Matsuda Y and Ishikawa T.
- Journal Title
  
  Cancer Sci. 98(2)
  
  Pages: 231-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.2007
- Author(s)
  Sakurai A, Kurata A, Onishi Y, Hirano H and Ishikawa T.
- Journal Title
  
  Expert Opin. Drug Saf. 6(1)
  
  Pages: 71-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Quantitative SAR analysis and molecular dynamic simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1.2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M and Ishikawa T.
- Journal Title
  
  Biochemistry 46(26)
  
  Pages: 7678-7693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.2007
- Author(s)
  Tamura A, Onishi Y, An R, Koshiba S, Wakabayashi K, Hoshijima K, Priebe W, Yoshida T, Kometani, S, Matsubara T, Mikuriya K, and Ishikawa, T.
- Journal Title
  
  Drug Metab. Pharmacokin. 22(6)
  
  Pages: 428-440
- NAID
  10020163594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in Osteoclast culture.2007
- Author(s)
  Nakagawa H, Hasumi K, Takami M, Aida-Hyugaji S, Woo JT, Nagai K, Ishikawa T, Wachi M.
- Journal Title
  
  Biochem. Pharmacol. 73・1
  
  Pages: 34-43
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Multidrug resistance-associated protein 9 (ABCC12) is present in sperm.2007
- Author(s)
  Ono N, van der Heiden I, Schffer GL, van de Wetering, van Deenter E, de Haas M, Boerke A, Gadella BM, de Rooij DG, Neefjes JJ, Groothuis TAM, Oomen L, Brocks L, Ishikawa T, and Borst P.
- Journal Title
  
  Biochem. J. 406(1)
  
  Pages: 31-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Quantitative SAR analysis and molecular dynamic simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1.2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M and Ishikawa T.
- Journal Title
  
  Biochemistry 46(26)
  
  Pages: 7678-7693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Theoretical studies for molecular modeling of new camptothecin analogues.2007
- Author(s)
  Aida-Hyugaji S, Nakagawa H, Nomura J, Sakurai M, Nagashima U and Ishikawa T.
- Journal Title
  
  Croatica Chemica Acta 80(2)
  
  Pages: 277-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Identification of two biologically crucial hydroxyl groups of(-)-epigallocatechin gallate in osteoclast culture.2007
- Author(s)
  Nakagawa H, Hasumi K, Takami M, Aida-Hyugaji S, Woo JT, Nagai K, Ishikawa T and Wachi M.
- Journal Title
  
  Biochem. Pharmacol. 73(1)
  
  Pages: 34-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhition by drugs.2007
- Author(s)
  Tamura A, Onishi Y, An R, Koshiba S, Wakabayashi K, Hoshijima K, Priebe W, Yoshida T, Kometani, S, Matsubara T, Mikuriya K, and Ishikawa, T.
- Journal Title
  
  Drug Metab. Pharmacokin. 22(6)
  
  Pages: 428-440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659136
[Journal Article] Re-evaluation and functional classification of nonsynonymous single nucleotide polymorphisms of human ABC transporter ABCG2.2007
- Author(s)
  Tamura A, Wakabayashi K, Onishi Y, Takeda M, Ikigame Y, Sawada S, Tsuji M, Matsuda Y, Ishikawa T.
- Journal Title
  
  Cancer Sci. 98・2
  
  Pages: 231-239
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Development of polyclonal antibodies specific to ATP-binding casstte transporters human ABCG4 and mouse Abcg4: site-specific expression of mouse Abcg4 in brain.2007
- Author(s)
  Koshiba S, Ito T, Shiota A, Wakabayashi K, Ueda M, Ichinose H, and Ishikawa T.
- Journal Title
  
  J. Exp. Ther. Oncol. 6
  
  Pages: 321-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2 : a new approach using the flp recombinase system.2006
- Author(s)
  Wakabayashi K, Nakagawa H, Adachi T, Kii I, Kobatake E, Kudo A, Ishikawa T.
- Journal Title
  
  J. Exp. Ther. Oncol. 5・3
  
  Pages: 205-222
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Human ABC transporter ABCG2 in xenobiotic protection and redox biology.2006
- Author(s)
  Wakabayashi K, Tabura A, Saito H, Onishi Y, Ishikawa T.
- Journal Title
  
  Drug Metab. Rev. 38・3
  
  Pages: 371-391
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer.2006
- Author(s)
  Nakagawa H, Saito H, Ikegami Y, Aida-Hyugaji S, Sawada S, Ishikawa T
- Journal Title
  
  Cancer Lett 234(1)
  
  Pages: 81-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.2006
- Author(s)
  Ishikawa T, Ikegami Y, Sano K, Nakagawa H, Sawada S
- Journal Title
  
  Curr. Pharm. Des 12(3)
  
  Pages: 313-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] A new strategy of higy-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions.2006
- Author(s)
  Saito H, Hirano H, Nakagawa H, Fukami T, Oosumi K, Murakami K, Kimura H, Kouchi T, Konomi M, Tao E, Tsujikawa N, Tarui S, Nagakura M, Osumi M, Ishikawa T.
- Journal Title
  
  J. Pharmacol. Exp. Ther. 317・3
  
  Pages: 1114-1124
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Molecular modeling of new camptothecin analogues to circumvent ABCG2-mediated drug resistance in cancer.2006
- Author(s)
  Nakagawa H, Saito H, Ikegami Y, Aida-Hyugaji S, Sawada S, Ishikawa T.
- Journal Title
  
  Cancer Lett. 234・1
  
  Pages: 81-89
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] A SNP in the ABCC11 gene is the determinant of human earwax type.2006
- Author(s)
  Yoshiura K, Kinoshita A, Ishida T, Ninokata A, Ishikawa T, 他34名
- Journal Title
  
  Nat. Genet. 38・3
  
  Pages: 324-330
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Genetic polymorphisms of human ABC transporter ABCG2 : Development of the standard method for functional validation of SNPs by using the Flp recombinase system.2006
- Author(s)
  Tamura A, Wakabayashi K, Onishi Y, Nakagawa H, Tsuji M, Matsuda Y, Ishikawa T.
- Journal Title
  
  J. Exp. Ther. Oncol. 6・1
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Evaluation of Human P-Glycoprotein (MDR1/ABCB1) ATPase Activity Assay Method by Comparing with in Vitro Transport Measurements : Michaelis-Menten Kinetic Analysis to Estimate the Affinity of P-Glycoprotein to Drugs. Biol.2006
- Author(s)
  Shirasaka Y, Onishi Y, Sakurai A, Nakagawa H, Ishikawa T, Yamashita S.
- Journal Title
  
  Pharm. Bull. 29・12
  
  Pages: 2465-2471
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2 : identification of alleles that are defective in porphyrin transport.2006
- Author(s)
  Tamura A, Watanabe M, Saito H, Nakagawa H, Kamachi T, Okura I, Ishikawa T.
- Journal Title
  
  Mol. Pharmacol. 70・1
  
  Pages: 287-296
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Transport mechanism-based drug molecular design : novel comptothecin analogues to circumvent ABCG2-associated drug resistance of humand tumor cells.2006
- Author(s)
  Ishikawa T, Ikegame Y, Sano K, Nakagawa H, Sawada S.
- Journal Title
  
  Curr. Pharm. Des. 12・3
  
  Pages: 313-325
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] A new strategy of high-speed screening and quantitative structure-activity relationship analysis to evaluate human ATP-binding cassette transporter ABCG2-drug interactions.2006
- Author(s)
  Saito H, Hirano H, Nakagawa H, Fukami T, Oosumi K, Murakami K, Kimura H, Kouchi T, Konomi M, Tao E, Tsujikawa N, Tarui S, Nagakura M, Osumi M, Ishikawa T
- Journal Title
  
  J. Pharmacol. Exp. Ther 317(3)
  
  Pages: 1114-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] High-Speed Screening and QSAR Analysis of Human ATP-Binding Cassette Transporter ABCB11 (Bile Salt Export Pump) To Predict Drug-Induced Intrahepatic Cholestasis.2006
- Author(s)
  Hirano H, Kurata A, Onishi Y, Sakurai A, Saito H, Nakagawa H, Nagakura M, Tarui S, Kanamori Y, Kitajima M, Ishikawa T
- Journal Title
  
  Mol. Pharm 3(3)
  
  Pages: 252-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] Nuclear receptor-mediated xenobiotic procession loops in hpase I, II, and III drug metabolizing systems.2006
- Author(s)
  Nakata K, Tanaka Y, Nakano T, Adachi T, Tanaka H, Kaminuma T, Ishikawa T.
- Journal Title
  
  Drug Metab. Pharmacokinet. 21
  
  Pages: 437-457
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] High-Speed Screening and QSAR Analysis of Human ATP-Binding Cassette Transporter ABCB11 (Bile Salt Export Pump) to Predict Drug-Induced Intrahepatic Cholestasis.2006
- Author(s)
  Hirano H, Kurata A, Onishi Y, Sakurai A, Saito H, Nakagawa H, Nagakura M, Tarui S, Kanamori Y, Kitajima M, Ishikawa T.
- Journal Title
  
  Mol. Pharm. 3・3
  
  Pages: 252-265
- Data Source
  KAKENHI-PROJECT-18201041
[Journal Article] High-speed screening of human ABC transporter function and genetic polymorphisms : New strategies in pharmacogenomics.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Methods in Enzymol 400(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Transport mechanism-based drug molecular design : novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Current Pharm. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Pharmacogenomics of the human ABC transporter ABCG2 : from functional evaluation to drug molecular design.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Naturwissenschaften (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Pharmacogenomics of the human ABC transporter ABCG2 : from functional evaluation to drug molecular design.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Naturwissenschaften (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Transport mechanism-based drug molecular design : novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Current Pharm.Design (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] High-speed screening of human ABC transporter function and genetic polymorphisms : New strategies in pharmacogenomics.2005
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Methods in Enzymol (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] high-speed screening of human ABC transporter function and genetic polymorphisms : New strategies in pharmacogenomics.2005
- Author(s)
  T.Ishikawa
- Journal Title
  
  Nethods in Enzymol. 400
  
  Pages: 485-510
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] The genetic polymorphism of drug transpoters : functional analysis approaches.2004
- Author(s)
  Ishikawa T., Tsuji A., Inui K., Sai Y., Anzai N., Wada M., Endou H., Sumino Y.
- Journal Title
  
  Pharmacogenomics 5
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Evaluation of in vivo selective binding of [^<11>C]doxepine to histamine H_1 receptors in five animal species.2004
- Author(s)
  K.Ishikawa
- Journal Title
  
  Nucl.Med.Biol. 31・4
  
  Pages: 493-502
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] Pharmacogenomics of drug transporters : a new approach to functional analysis of the genetic polymorphisms of ABCB1(P-glycoprotein/MDR1)2004
- Author(s)
  T.Ishikawa
- Journal Title
  
  Biol.Pharm.Bull. 27・7
  
  Pages: 939-948
- NAID
  110003608891
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] The genetic polymorphism of drug transpoters : functional analysis approaches.2004
- Author(s)
  T.Ishikawa
- Journal Title
  
  Pharmacogenomics 5・1
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid.2004
- Author(s)
  Yoshikawa, M., Ikegami, Y., Sano, K., Yoshida, H., Mitomo, H., Sawada, Ishikawa, T.
- Journal Title
  
  J. Exp. Ther. Oncol. 4
  
  Pages: 25-35
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] The genetic polymorphism of drug transporters : functional analysis approaches2004
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Pharmacogenomies 5
  
  Pages: 67-99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Novel camptothecin analogues that circumvent ABCG 2-associated drug resistance in human tumor cells.2004
- Author(s)
  Yoshikawa, M., Ikegami, Y., Hayasaka, S., Ishii, K., Ito, A., Sano, K., Suzuki, T., Togawa, T., Yoshida, H., Soda, H., Oka, M., Kohno, S., Sawada, S., Ishikawa, T., Tanabe, S.
- Journal Title
  
  Int. J. Cancer 110
  
  Pages: 921-927
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] S. Functional evaluation of ABCB1 (P-Glycoprotein) polymorphisms : High-speed screening and Structure-activity relationship analyses.2004
- Author(s)
  Ishikawa, T., Hirano, H., Onishi, Y., Sakurai, A., Tarui
- Journal Title
  
  Drug Metabol. Pharmacokin. 19
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Functional evaluation of ABCB1 (P-Glycoprotein) polymorphisms : High-speed screening and Structure-activity relationship analyses.2004
- Author(s)
  T.Ishikawa
- Journal Title
  
  Drug Metabol.Pharmacokin. 19・1
  
  Pages: 1-14
- NAID
  10012688427
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] Functional Evaluation of ABCB1 (P-Glycoprotein) Polymorphisms : High-Speed Screening and Structure- Activity Relationship Analyses2004
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Drug Metabol.Pharmacokin. 19
  
  Pages: 1-4
- NAID
  10012688427
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Functional Evaluation of ABCB1(P-Glycoprotein) Polymorphisms : High-Speed Screening and Structure-Activity Relationship Analyses.2004
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Drug Metabol.Pharmacokin. 19
  
  Pages: 1-4
- NAID
  10012688427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] The genetic polymorphism of drug transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Pharmacogenomics 5
  
  Pages: 67-99
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Pharmacogenomics of Drug Transporters : A New Approach to Functional Analysis of the Genetic Polymorphisms of ABC B1(P-Glycopprotein/MDR1).2004
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Bio.Pharm.Bull. 27
  
  Pages: 939-948
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Multidrug Resistance : Genetics of ABC Transporters2003
- Author(s)
  Ishikawa, T.
- Journal Title
  
  Nature Encyclopedia of the Human Genome 4
  
  Pages: 154-160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Expression and Functional Characterization of Human ABC Transporter ABCG2 Variants in Insect Cells.2003
- Author(s)
  Ishikawa, T., et al.
- Journal Title
  
  Drug Metabol.Pharmacokin. 18
  
  Pages: 194-202
- NAID
  10011426121
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Journal Article] Multidrug Resistance : Genetics of ABC Transporters. In : Cooper DN(ed.)2003
- Author(s)
  Ishikawa, T.
- Journal Title
  
  Nature Encyclopedia of the Human Genome(London, Nature Publishing Group) 4
  
  Pages: 154-160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370754
[Patent] 治療抵抗性がんの予防又は治療用組成物2014
- Inventor(s)
  石川智久, 黒岩敏彦, 梶本宜永, 藤城高広, 木村誠吾, 宮武伸一, 田中徹
- Industrial Property Rights Holder
  理化学研究所, 大阪医科大学, SBIファーマ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-031220
- Filing Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] 治療抵抗性がんの予防用又は治療用組成物2014
- Inventor(s)
  石川智久、黒岩敏彦、梶本宜永　他
- Industrial Property Rights Holder
  理化学研究所、大阪医科大学、SBIファーマ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-031220
- Filing Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] 化合物の生理活性の定量的予測方法2012
- Inventor(s)
  平野弘之, 辻川登, 石川智久
- Industrial Property Rights Holder
  石川智久, 辻川登
- Industrial Property Rights Type
  特許
- Acquisition Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] 化合物の生理活性の定量的予測方法2012
- Inventor(s)
  平野弘之, 辻川登, 石川智久
- Industrial Property Rights Holder
  石川智久, 辻川登(すべての指定国)平野弘之(米国のみ)
- Industrial Property Rights Type
  特許
- Acquisition Date
  2012-08-31
- Overseas
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] Photodynamic treatment of brain tumor2012
- Inventor(s)
  Toshihisa Ishikawa
- Industrial Property Rights Holder
  Toshihisa Ishikawa
- Industrial Property Rights Type
  特許
- Filing Date
  2012-09-11
- Overseas
- Data Source
  KAKENHI-PROJECT-23650619
[Patent] 抗ガン剤耐性克服剤2007
- Inventor(s)
  平野益治、山川富雄、石川智久、齊藤光
- Industrial Property Rights Holder
  日本ケミファ株式会社
- Filing Date
  2007-12-27
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 化合物の生理活性の定量的予測方法2006
- Inventor(s)
  平野弘之、辻川登、石川智久
- Industrial Property Rights Holder
  石川智久、辻川登(すべての指定国)平野弘之(米国のみ)
- Filing Date
  2006-06-30
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 遺伝子多型の検出方法および薬物のスクリーニング方法2006
- Inventor(s)
  石川智久, 櫻井亜季, 田村藍
- Industrial Property Rights Holder
  東京工業大学
- Filing Date
  2006-08-30
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 化合物の生理活性の定量的予測方法2006
- Inventor(s)
  平野弘之、辻川登、石川智久
- Industrial Property Rights Holder
  石川智久、辻川登
- Filing Date
  2006-06-16
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 化合物の生理活性の定量的予測方法2006
- Inventor(s)
  平野弘之、辻川登、石川智久
- Industrial Property Rights Holder
  平野弘之、辻川登、石川智久
- Filing Date
  2006-06-30
- Overseas
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 遺伝子多型の検出方法および薬物のスクリーニング方法2006
- Inventor(s)
  石川智久、櫻井亜季、田村藍
- Industrial Property Rights Holder
  国立大学法人東京工業大学
- Filing Date
  2006-08-30
- Overseas
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 化合物の生理活性の定量的予測方法2006
- Inventor(s)
  平野弘之、辻川登、石川智久
- Industrial Property Rights Holder
  石川智久、辻川登
- Industrial Property Number
  2006-167002
- Filing Date
  2006-06-16
- Data Source
  KAKENHI-PROJECT-18201041
[Patent] 遺伝子多型の検出方法および薬物のスクリーニング方法2006
- Inventor(s)
  石川智久、櫻井亜季、田村藍
- Industrial Property Rights Holder
  国立大学法人東京工業大学(米国を除く全ての指定国)石川智久、櫻井亜季、田村藍(米国のみ)
- Filing Date
  2006-08-30
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] 5-Aminolevulinic Acid (ALA)-Based Photodynamic Therapy of Malignant Brain Tumors and Glioma Stem Cells : From Basic Research to Clinical Applications of an ABCG2 Inhibitor2014
- Author(s)
  Ishikawa T, Fujishiro T, Kajimoto Y, Inoue Y, Ikegami Y, Kuroiwa T
- Organizer
  FEBS ATP-Binding Cassette (ABC) Proteins
- Place of Presentation
  オーストリア Innsbruck
- Year and Date
  2014-03-12
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍のALA 光線力学診断・治療に向けて : In silico 創薬分子デザインから臨床応用へ2014
- Author(s)
  石川智久
- Organizer
  第347回CBI 学会研究講演会
- Place of Presentation
  東京
- Year and Date
  2014-02-24
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] New challenges in human ABC transporters research : From bench to clinical practice (Keynote lecture)2013
- Author(s)
  Ishikawa T
- Organizer
  International Conference on Role of MDR proteins in pharmacokinetics and toxicology
- Place of Presentation
  ポーランド, Ryn, Zamek Ryn Hotel
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の多剤耐性トランスポーターのファーマコゲノミクス : 基礎研究から個別化医療に向けた新たな挑戦2013
- Author(s)
  石川智久
- Organizer
  愛媛大学医学部セミナー
- Place of Presentation
  愛媛大学医学部
- Year and Date
  2013-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 黒岩敏彦, 石川智久
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  東京
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割 : ABCG2遺伝子の発現調節2013
- Author(s)
  石川智久, 梶本宜永, Wei Sun , 井上裕貴, 池上洋二, 萩谷祐一郎, 小倉俊一郎, 宮武伸一, 黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The role of Nrf2 in photodynamic therapy : Regulation of ABCG2 gene expression2013
- Author(s)
  Ishikawa T, Kajimoto Y, Inoue Y, Ikegami Y, Nakagawa Y, Kuroiwa T
- Organizer
  日本生化学会2013年次大会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 黒岩敏彦, 石川智久
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2013-10-02
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2 阻害剤のデザイン2013
- Author(s)
  井上裕貴, 池上洋二, 佐野和美, 小金井美穂, 吉田久博, 藤城高広, 木村誠吾, 深見竹広, 梶本宜永, 宮武伸一, 黒岩敏彦, 石川智久
- Organizer
  ポルフィリンALA 学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2 の役割 : ABCG2 遺伝子発現の制御2013
- Author(s)
  石川智久, 井上裕貴, 池上洋二, 中川大, 黒岩敏彦
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  東京
- Year and Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Pharmacogenomics of Drug Transporters and Clinical Applications2013
- Author(s)
  Ishikawa T
- Organizer
  The 2nd International Conference on Translational & Personalized Medicine
- Place of Presentation
  米国シカゴHoliday Inn Chicago-North Shore
- Year and Date
  2013-08-07
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍幹細胞様細胞に対する5-ALA PDT 感受性の評価2013
- Author(s)
  藤城高広, 梶本宜永, 木村誠吾, 宮武伸一, 石川智久, 黒岩敏彦
- Organizer
  ポルフィリンALA 学会
- Place of Presentation
  横浜
- Year and Date
  2013-04-27
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Point-of-Care Technology for Personalized Medicine2013
- Author(s)
  Ishikawa T
- Organizer
  Bio-IT World & Molecular Med TRI-CON ASIA
- Place of Presentation
  シンガポール
- Year and Date
  2013-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2012
- Author(s)
  Ishikawa T, Takahashi K, Ikeda N, Kajimoto Y, Hagiya Y, Ogura S, Saito H, Miyatake S-I, Kuroiwa T
- Organizer
  薬物動態国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Pharmacogenomics of Human ABC Transporters : From Bench to Bedside2012
- Author(s)
  Ishikawa T
- Organizer
  Personalized Medicine in Cancer Treatment
- Place of Presentation
  中国 Shenzhen
- Year and Date
  2012-07-13
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: molecular design of ABCG2 inhibitors2012
- Author(s)
  Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T., Ishikawa, T.
- Organizer
  International Forum “Patients and Medicines"
- Place of Presentation
  理化学研究所（横浜）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors2012
- Author(s)
  Toshihisa Ishikawa, Kenkichi Takahashi, Naokado Ikeda, Yoshinaga Kajimoto, Yuichiro Hagiya, Shun-ichiro Ogura, Hikaru Saito, Shin-ichi Miyatake, and Toshihiko Kuroiwa
- Organizer
  International Symposium on PPF Molecular Pharmacokinetics
- Place of Presentation
  一橋記念講堂（東京）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] ポルフィリンを輸送するヒトABC トランスポーターABCG2 の遺伝子多型 : 迅速SNP 検出法の開発2012
- Author(s)
  櫻井亜季, Alexander Lezhava, 林崎良英, 石川智久
- Organizer
  第2回ポルフィリンALA 学会
- Place of Presentation
  横浜
- Year and Date
  2012-04-28
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Transporter-mediated drug interaction strategy for ALA-based photodynamic diagnosis of malignant brain tumor : molecular design of ABCG2 inhibitors2012
- Author(s)
  Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T., Ishikawa, T
- Organizer
  International Forum "Patients and Medicines"
- Place of Presentation
  横浜
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-based photodynamic diagnosis of malignant brain tumor : Molecular design of ABCG2 inhibitors2012
- Author(s)
  Ishikawa T., Kuroiwa T
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Recent Advances in the Human ABC Transporters Research : From Bench to Bedside2011
- Author(s)
  Ishikawa T
- Organizer
  ABC Symposium 2011
- Place of Presentation
  京都
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Screening of transporters involved in porphyrin accumulation after administration of 5-aminolevulinic acid in vitro2011
- Author(s)
  Matsumoto K, Hagiya Y, Nakagawa H, Ishikawa T, Ogura S
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Molecular fluorescence imaging to assist neurosurgery of malignant brain tumors in humans : from bench to bedside2011
- Author(s)
  Ishikawa, T., Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Molecular fluorescence imaging to assist neurosurgery of malignant brain tumors in humans: from bench to bedside2011
- Author(s)
  Ishikawa, T., Takahashi, K., Ikeda, N., Kajimoto, Y., Hagiya, Y., Ogura, S., Miyatake, S., Kuroiwa, T.
- Organizer
  13th Japanese-German Cancer Workshop(招待講演)
- Place of Presentation
  グランドプリンスホテル広島（広島）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The Pivotal Role of PEPT1 and ABCG2 on 5-Aminolevulinic Acid (ALA)-based Photodynamic Sensitization of Cancer Cells in Vitro2011
- Author(s)
  Hagiya Y, Endo Y, Yonemura Y, Takahashi K, Ishizuka M, Abe F, Nakajima M, Ishikawa T, Ogura S
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Recent Advances in the Human ABC Transporters Research: From Bench to Bedside2011
- Author(s)
  Ishikawa T
- Organizer
  ABC 2011 in Kyoto　(招待講演)
- Place of Presentation
  京都大学（京都）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Screening of transporters involved in porphyrin accumulation after administration of 5-aminolevulinic acid in vitro2011
- Author(s)
  Kentaro Matsumoto, Yuichiro Hagiya, Hiroshi Nakagawa, Toshihisa Ishikawa, Shun-ichiro Ogura
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The Pivotal Role of PEPT1 and ABCG2 on 5-Aminolevulinic Acid (ALA)-based Photodynamic Sensitization of Cancer Cells in Vitro2011
- Author(s)
  Yuichiro Hagiya, Yoshio Endo, Yutaka Yonemura, Kiwamu Takahashi, Masahiro Ishizuka, Fuminori Abe, Motowo Nakajima, Toshihisa Ishikawa, Shun-ichiro Ogura
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] QSAR-based prediction and identification of novel dual inhibitors against ABCG2/BCRP and protein kinases2010
- Author(s)
  Saito, H., Hirano, H., Ishikawa, T.
- Organizer
  3^<rd> FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] QSAR-based prediction and identification of novel dual inhibitors against ABCG2/BCRP and protein kinases2010
- Author(s)
  Saito, H., Hirano, H., Ishikawa, T
- Organizer
  3rd FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] The impacts of posttranslational modifications and non-synonymous SNPs on the protein stability of human ABC transporter ABCG2 protein in culture cells2010
- Author(s)
  Nakagawa, H., Wakabayashi-Nakao, K., Tamura, A., Toyoda, Y., Koshiba, S., Furukawa, T., Ishikawa, T.
- Organizer
  3rd FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Pharmacogenomics of human ABC transporters : from functional validation to clinical application2010
- Author(s)
  Ishikawa, T., Aw, W., Saito, H., Toyoda, Y., Nakagawa, H., Lezhava, A., Hayashizaki, Y.
- Organizer
  3^<rd> FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Phamacogenomics of human ABC transporters : from functional validation to chnical application2010
- Author(s)
  Ishikawa, T., Aw, W., Saito, H., Toyoda, Y., Nakagawa, H., Lezhava, A., Hayashizaki, Y.
- Organizer
  3^<rd> FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Earwax, osmidrosis, and breast cancer : why does one SNP(538G>A)in the human ABC transporter ABCC11 gene determine earwax type?2010
- Author(s)
  Toyoda, Y., Nakagawa, H., Aw, W., Lezhava, A., Hayashizaki, Y., Niikawa, N., Ishikawa, T.
- Organizer
  3^<rd> FEBS Special Meeting on ABC Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Genetic Polymorphisms of ABC Transporters in Cancer Chemotherapy : Development of SmartAmp2 Method for Clinical Genetic Testing2010
- Author(s)
  Ishikawa, T., Aw, W., Ledhava, A., Hayashizaki, Y.
- Organizer
  AACR Conference on ranslational Cancer Medicine 2010(Europe)
- Place of Presentation
  Amsterdam、オランダ
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Biochemical characterization of human ABC transporter ABCC11 : Its genetic polymorphism determining earwax type2009
- Author(s)
  Toyoda, Y., Nakagawa, H., Nakashima, M., Yoshiura, K., Niikawa, N., Ishikawa, T.
- Organizer
  The 5^<th> Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  東京
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Human ABC transporter ABCC11 : genetic polymorphisms and molecular mechanisms determining the type of earwax2009
- Author(s)
  Ishikawa, T., Toyoda, Y., Yoshiura, K., Niikawa, N.
- Organizer
  The 5^<th> Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  東京
- Year and Date
  2009-05-26
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Identification and Inhibitory Characterization of Protein Kinase Inhibitors Based on QSAR Analysis of Human ABC Transporter ABCG22009
- Author(s)
  Saito, H., Hirano, H., Ishikawa, T.
- Organizer
  The 5th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Three-Dimensional SAR analysis of protein kinase inhibitors identified by QSAR analysis of human ABC transporter ABCG22009
- Author(s)
  Saito, H., Nakagawa, H, Ishikawa, T.
- Organizer
  日本がん学会総会
- Place of Presentation
  (パシフィコ横浜)横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent Induction of Human ABC Transporter ABCG2 and Heme oxygenase-1 in HepG2 cells by Photoactivation of Porphirins: Biochemical Implications for Cancer Cell Response to Photodynamic Therapy2009
- Author(s)
  Hagiya, Y., Adachi, T., Ogura, S., An, R., Tamura, I., Nakagawa, H., Okura, I., Mochizuki, T., Ishikawa, T.
- Organizer
  The 5th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Genetic polymorphism in human ABC transporter ABCC11 gene : Potential association between earwax and breast cancer risk2009
- Author(s)
  Toyoda, Y., Ota, I., Ishikawa, T., Lezhava, A., Hayashizaki, Y., Ishikawa, T.
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] N-linked glycosylation stabilizes the de novo synthesized human ABC transporter ABCG2 protein2009
- Author(s)
  Nakagawa, H., Wakabayashi-Nakao, K., Tamura, A., Ishikawa, T.
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] N-linked glycosylation stabilizes the de novo synthesized human ABC transporter ABCG2 protein2009
- Author(s)
  Nakagawa, H., Wakabayashi-Nakao, K., Tamura, A., Ishikawa, T.
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Pharmacogenomics of human ABC transporters : From functional SNP analysis to application of SmartAmp2 method in clinical research2009
- Author(s)
  Ishikawa, T., Lezhava, A., Hayashizaki, Y.
- Organizer
  24^<th> JSSX Annual Meeting
- Place of Presentation
  京都
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] 薬物トランスポーターの遺伝子多型の機能解析:国際標準化からFDA白書まで2009
- Author(s)
  石川智久
- Organizer
  イノベーションジャパン
- Place of Presentation
  東京
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Identification and Inhibitory Characterization of Protein Kinase Inhibitors Based on QSAR Analysis of Human ABC Transporter ABCG22009
- Author(s)
  Saito, H., Hirano, H., Ishikawa, T.
- Organizer
  The 5^<th> Takeda Science Foundation Symposium on PharmaSciences, Tokyo, Japan
- Place of Presentation
  (GRAND PRINCE HOTEL TAKANAWA)東京
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Three-Dimensional SAR analysis of protein kinase inhibitors identified by QSAR analysis of human ABC transporter ABCG22009
- Author(s)
  Saito, H., Nakagawa, H., Ishikawa, T.
- Organizer
  68th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent Induction of Human ABC Transporter ABCG2 and Heme oxygenase-1 in HepG2 cells by Photoactivation of Porphirins : Biochemical Implications for Cancer Cell Response to Photodynamic Therapy2009
- Author(s)
  Hagiya, Y., Adachi, T., Ogura, S, An, R., Tamura, I., Nakagawa, H., Okura, I., Mochizuki, T., Ishikawa, T.
- Organizer
  The 5^<th> Takeda Science Foundation Symposium on PharmaSciences, Tokyo, Japan
- Place of Presentation
  (GRAND PRINCE HOTEL TAKANAWA)東京
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Monomeric non-glycosylated form of human ATP-binding cassette transporter ABCG2 is the most fragile in culture cells2009
- Author(s)
  Nakagawa, H., Wakabayashi-Nakao, K., Tamura, A., Koshiba, S., Toyoda, Y., Ishikawa, T.
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] FDA Critical Path Transporter Workshop の報告2009
- Author(s)
  石川智久
- Organizer
  第23回日本薬物動態学会ワークショップ
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Association between the wild type allele in human ABC transporter ABCC11 gene and breast cancer risk : Evaluation by the SmartAmp2 method2009
- Author(s)
  Ishikawa, T., Toyoda Y, Ota, I., Lezhava, A., Ishikawa, T., Hayashizaki, Y.
- Organizer
  AACR Special Conference in Breast Cancer Research
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Impact of Major Non-synonymous SNP(Q141K)on Proteolysis of Human ABC Transporter ABCG2 via Lysosomal and Ubiquitin-mediated Proteasomal Degradation Pathways2009
- Author(s)
  Furukawa, T., Wakabayashi-Nakao, K., Tamura, A., Nakagawa, H., Ishikawa, T.
- Organizer
  The 50^<th> Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  東京
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] SNP(G538A)of the human ABC transporter ABCC11 correlates with earwax type and breast cancer risk2009
- Author(s)
  Ishikawa, T., Nakagawa, H., Toyoda, Y., Saito, H., Hayashizaki, Y.
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Expression mechanism of ABCC2 by LXR ligand T0901317 is different from that of ABCGl2008
- Author(s)
  Adachi T, Nakagawa H, Hoshijima K, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Ehenic differences, functional validation and rapid detection of nonsynonymou SNP 2677G>T/A in human ABCB1 gene2008
- Author(s)
  Sakurai A, Onishi Y Hirano H, Sakurai M, Kawai Y, Mitani Y, Lezhava A, Hayashizaki Y, Ishikawa T.
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Ethnic differences, functional validation and rapid detection of nonsynonymous SNP 2677>T/A in human ABCB1 gene2008
- Author(s)
  Sakurai A、Onishi Y、Hirano H、Sakurai M、Kawai Y、Mitani Y、Lezhava A、Hyashizaki Y、Ishikawa T
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells by photoactivation of porphyrins: Biochemical implications for cancer cell response to photodynamic therapy2008
- Author(s)
  Hagiya Y、Adachi T、Ogura S、An R、Tamura A、Nakagawa H、Okura I、Mochizuki T、Ishikawa T
- Organizer
  Gordon Research Conference
- Place of Presentation
  U.S.A. New Hampshire
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Development of Polyclonal antibodies specific to human ABCG4 and mouse Abcg4: site-specific expression of mouse Abcg4 in brain2008
- Author(s)
  Koshiba S, Ito T, Wakabayashi K, Ichinose H, Ishikawa T.
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Ethnic differences. functional validation and rapid detection of nonsynonymous SNP 2677>T/A in human ABCB1 gene2008
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Sakurai M, Kawai Y Mitani Y,Lezhava A. Hyashizaki Y. Ishikawa T.
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Molecular characterization of ATP-binding cassette transporters human ABCG4 and mouse Abcg42008
- Author(s)
  Koshiba S, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type.2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N, Ishikawa T.
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] International Standardization of in vitro Assay Methods for Drug Transporters : Establishment of Transporter Working Group2008
- Author(s)
  Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Cellular phototoxicity evoked through the inhibition of human ABC transporer ABCG2 by cyclin-dependent kinase inhibitors in vitro2008
- Author(s)
  An R, Hagiya Y Tamura A, Li S, Saito H, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Transporter mechanism-based drug molecular design: High-speed screening, QSAR analysis and molecular orbital calculation2008
- Author(s)
  Ishikawa, T.
- Organizer
  IPAB/AHeDD Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] In Vitro Functional Validation of Genetic Polymorphisms of Human ABCG2 : Identification of Alleles That Are Defective in Porphyrin Transport2008
- Author(s)
  Tamura A, An R, Nakagawa H, Okura I, Ishikawa T
- Organizer
  第8回国際ポルフィリンヘムシンポジウム
- Place of Presentation
  島根
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Genetic Polymorphisms of ABCG2 and ER-associated Degradation (ERAD) Pathway2008
- Author(s)
  Wakabayashi K, Tamura A, An R, Hoshijima K, Nakagawa H, Ishikawa T.
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Identification and Inhibitory Characterization of Protein Kinase Inhibitors Based on QSAR Analysis of Human ABC Transporter ABCG22008
- Author(s)
  Saito H, Hirano H, Hirono S, Tokushima D, Ishikawa T.z
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Quantitative structure-activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABCG1 (P-glycoprotein/MDR1)2008
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T,
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Development of Polyclonal antibodies specific to human ABCG4 and mouse Abcg4: site-specific expression of mouse Abcg4 in brain2008
- Author(s)
  Koshiba S, Ito T, Wakabayashi K, Ichinose H, Ishikawa T.
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Identification and Inhibitory Characterization of Protein Kinase Inhibitors Based on QSAR Analysis of Human ABC Transporter ABCG22008
- Author(s)
  Saito H, Hirano H, Hirono S, Tokushima D, Ishikawa T.z
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Impact of major non・synonymous SNP(Q141K)on proteolysis of ABCG2 via lysosomal and proteasomal degradation pathways2008
- Author(s)
  Tamura A, Wakabayashi K, An R, Furukawa T, Ishikawa T.
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] In Vitro Functional Validation of Genetic Polymorphisms of Human ATP-binding Cassette Transporter ABCB11 (SPGP/BSEP)2008
- Author(s)
  Nakamura R. Sakurai A Ishikawa T.
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type.2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N, Ishikawa T.
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Basic research and current knowledge on BCRP2008
- Author(s)
  Ishikawa, T.
- Organizer
  FDA Critical Path Transporter Workshop
- Place of Presentation
  Bethesda, MD, USA
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Human ABC transporter ABCG2: in vitro assay methods for drug molecular design and clinical application of pharmacogenomics2008
- Author(s)
  Ishikawa, T.
- Organizer
  AstraZeneca Seminar
- Place of Presentation
  Wilmington, USA
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Impact of Major Non-synonymous SNP (Q141K)on Proteolysis of Human ABC Transporter ABCG2 via Lysosomal and Ubiquitin-midiated Proteasomal Degradation Pathways2008
- Author(s)
  Furukawa T, Wakabayashi K, . Tamura A, Nakagawa H, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type.2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N, Ishikawa T.
- Organizer
  2008 桐蔭国際シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Pharmacogenomics of human ABC transporters: functional validation and detection of clinically important SNPs2008
- Author(s)
  Ishikawa, T.
- Organizer
  National Cancer Institute (NCI), NIH
- Place of Presentation
  Bethesda, MD, USA
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of human ATP-binding cassette transporter ABCG2.2008
- Author(s)
  Nakagawa H, Wakabayashi K, Tamura A, Koshiba S, Toyoda Y, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N, Ishikawa T.
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Nrf2-dependent Induction of ABCG2 and HO-1 by Photoactivation of Porphyrins : Implications for Photodynamic Therapy2008
- Author(s)
  Hagiya Y, Tamura A, Ishikawa T.
- Organizer
  2008 日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] SAR in ABC transporters2008
- Author(s)
  Ishikawa, T.
- Organizer
  AAPS Annual Meeting
- Place of Presentation
  Atlanta, USA
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Cellular Phototoxicity Evoked Through the inhibition of Human ABC Transporter ABCG2 by Cyclin-dependent Kinase Inhibitors In Vitro2008
- Author(s)
  An R, Hagiya Y, Tamura A, Li S, Saito H, Ishikawa T.
- Organizer
  2008 桐蔭国際シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Prediction of Drug-induced Intrahepatic Cholestasis : In Vitro Screening and QSAE Analysis of Drug Inhibiting the Human Bile Salt Export Pump(BSEP/ABCBn)2008
- Author(s)
  Shin w, Saito H, Nakamura R, Sakurai A, Ishikawa T.
- Organizer
  2008桐蔭国際シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent Induction of Human ABC Transporter ABCG2 and Heme oxygenase-1 in HepG2 cells by Photoactivation of Porphyrins : Biochemical Implications for Cancer Cell Response to Photodynamic Therapy2008
- Author(s)
  Hagiya Y, Adachi T, Ogura S, An R, Tamura A, Nakagawa H, Okura I, Mochizuki T, Ishikawa T.
- Organizer
  第8回国際ポルフィリンヘムシンポジウム
- Place of Presentation
  島根
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] ヒトABCトランスポーターABCG2の遺伝子多型とERAD : ユビキチン化とプロテアゾーム分解2008
- Author(s)
  若林香菜子, 田村藍, 古川朋佳, 中川大, 石川智久
- Organizer
  トランスポーター研究会第2回関東支部会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] QSAR-based identification of novel dual inhibitors against ABCG2/BCRP and protein kinases2008
- Author(s)
  Saito H, Hirano H, Ishikawa T.
- Organizer
  Gordon Research Conference
- Place of Presentation
  U.S.A. New Hampshire
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent induction of human ABC transporter ABCG2 and hemeoxygenase-1 in HepG2 cells by photoactivation of porphyrins : Biochemical implications for cancer cell response to photodynamic therapy2008
- Author(s)
  Hagiya Y, Adachi T, Ogura S, An R, Tamura A, Nakagawa H, Okura I, Mochizuki T, Ishikawa T.
- Organizer
  Gordon Research Conference
- Place of Presentation
  U.S.A. New Hampshire
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Quantitative structure-activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABCG1 (P-glycoprotein/MDR1)2008
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T.
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Genetic Polymorphisms of ABCG2 and ER-associated Degradation (ERAD) Pathway2008
- Author(s)
  Wakabayashi K, Tamura A, An R, Hoshijima K, Nakagawa H, Ishikawa T.
- Organizer
  2nd FEBS Special Meeting ABC2008
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Why does one SNP in the human ABCC11 gene determine earwax type in Homo Sapiens?2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Yoshiura K, Nakagawa H, Niikawa N, Ishikawa T.
- Organizer
  トランスポーター研究会第2回関東支部会
- Place of Presentation
  東京
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Nrf2-dependent Induction of Humana ABC Transporter ABCG2 and Hemeoxygenase-1 in HepG2 cells by Photoactivation of Porphyrins2008
- Author(s)
  Hagiya Y, Adachi T, Ogura S, An R, Tamura A, Nakagawa H, Okura I, Mochizuki T, Ishikawa T
- Organizer
  日本分子生物学会・日本生化学会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] QSAR-based identification of novel dual inhibitors against ABCG2/BCRP and protein kinases2008
- Author(s)
  Saito H、Hirano H、Ishikawa T
- Organizer
  Gordon Research Conference
- Place of Presentation
  U.S.A.New Hampshire
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Biochemical characterization of a genetic polymorphism of human ABCC11 as a determinant of earwax type.2008
- Author(s)
  Toyoda Y, Sakurai A, Nakashima M, Nakagawa H, Yoshiura K, Niikawa N,Ishikawa T.
- Organizer
  2008 桐蔭国際シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Pharmacogenomics and QSAR analysis of human ABC transporter ABCG22008
- Author(s)
  Ishikawa, T.
- Organizer
  SymCYP Seminar
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Impact of major non-synonymous SNP(Q141K)on proteolysis of ABCG2 via lysosomal and proteasomal degradation pathways2008
- Author(s)
  Tamura A, Wakabayashi K, An R, Furukawa T, Ishikawa T.
- Organizer
  人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] ヒトの耳垢タイプはどのようにして決まるのか? ABCC11の一塩基多型とプロテアソーム分解2008
- Author(s)
  豊田優, 櫻井亜季, 中川大, 吉浦孝一郎, 新川詔夫, 石川智久
- Organizer
  2008「タンパク質の社会」班会議
- Place of Presentation
  沖縄
- Year and Date
  2008-11-25
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Development of polyclonal antibodies specific to ATP-binding cassette transporters human ABCG4 and mouse Abcg4: Site-specific expression of mouse Abcg4 in brain2007
- Author(s)
  Koshiba S, Ito T, Wakabayashi K, Ichinose H, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Development of specific antibodies against mouse ATP-binding cassette transporter Abcg4 and expression of Abcg4 in Sf9 insectcells.2007
- Author(s)
  Koshiba S, Ito T, Ichinose H., Ishikawa, T.
- Organizer
  AACR Annual Meeting 2007
- Place of Presentation
  Los Angeles, U.S.A
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Functional Validate Nonsynonymous Polymorphisms of Human ABCB1 Transporter ABCB1 (P-glycoprotein/MDR1)2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Liew Ei Leen, Obanayama K, Kim G, Sakurai M Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Evidence for ubiquitinqtion and degradation of non-synonymous SNP proteins of human ATP-binding cassette transporter ABCG22007
- Author(s)
  Nakagawa H, Tamura A, Wakabayashi K, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Evaluation and Functional Classification of Nonsynonymous Single Nucleotide Polymorphisms of Human ABC Transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Ikegami Y, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] International Standardization of the Methods for In-vitro Funtional Analysis of Drug Transporters2007
- Author(s)
  Ishikawa T
- Organizer
  8th International ISSX Meeting (Short Course2)
- Place of Presentation
  仙台
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] A New Strategy of High-Speed Screening and Quantitative SAR Analysis to Evaluate Human ABC Transporter ABCG2-Drug Interactions2007
- Author(s)
  Saito H, Hirano H, Osumi M, , Ishikawa T
- Organizer
  Gordon Research Conference on Drug Metabolism
- Place of Presentation
  NH U.S.A.
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] QSAR Analysis of Human ABC Transporter ABCB1 (P-GP/MDR1): Effect of SNPs on the Substrate Specificity toward CDK Inhibitors2007
- Author(s)
  Liew Ei Leen, Sakurai A, Hirano H, Seigneuret M, Ishikawa T
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Evaluation and Functional Classification of Nonsynonymous Single Nucleotide Polymorphisms of Human ABC Transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Ikegami Y, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] A New Strategy of High-Speed Screening and Quantitative SAR Analysis to Evaluate Human ABC Transporter ABCG2-Drug Interactions2007
- Author(s)
  Saito H, Hirano H, Osumi M, , Ishikawa T
- Organizer
  Gordon Research Conference on Drug Metabolism
- Place of Presentation
  NH U.S.A.
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Disulfide Bond Formation Plays a Crucial Role in Protein Stability of Human ABCG22007
- Author(s)
  Wakabayashi K, Nakagawa H, Tamura A, Hoshijima K, Komada M, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] High-Speed Screening and QSAR Analysis of Human ABC Transporter ABCG2 for Molecular Modeling of Anticancer Drugs2007
- Author(s)
  Saito H, Tamura A, Wakabayashi K, Sakurai A, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Nrf2-dependent and indepenndent transcriptional upregulation of ABCC1, ABCC2, ABCC3, and ABCG2 genes in HepG2 cells.2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M.T, Ishikawa T.
- Organizer
  AACR Annual Meeting 2007
- Place of Presentation
  Los Angeles, U.S.A.
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Functional validation of genetic plymorphisms of ABCB1 (P-glycoprotein/MDR1): Quantative SAR analysis and moleculae dynamic simulation2007
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T,
- Organizer
  Gordon Research Conference on Drug Metabolism
- Place of Presentation
  NH U.S.A.
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] High-Speed Screening and QSAR Analysis of Human ABC Transporter ABCG2 for Molecular Modeling of Anticancer Drugs2007
- Author(s)
  Saito H, Tamura A, Wakabayashi K, Sakurai A, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Functional validation of genetic plymorphisms of ABCB1(P-glycoprotein/MDR1): Quantative SAR analysis and moleculae dynamic simulation2007
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T,
- Organizer
  Gordon Research Conference on Drug Metabolism
- Place of Presentation
  NH U.S.A.
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Characterization and Classification of CDK Inhibitors by QSAR Analysis of Human ABC Transporter ABCG22007
- Author(s)
  Saito H, Hirano H, Hirono S, Tokushima D, Ishikawa T
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] ヒトABCトランスポーターABCG2のポルフィリン輸送における薬理学的役割:薬物によるABCG2の阻害と光毒性との関係2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M.T, Ishikawa T.
- Organizer
  第34回ポルフィリン研究会
- Place of Presentation
  東京
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Transport Mechanism-Based Drug Molecular Design: High-Speed Screening and Quantitative SAR Analysis of ABC Transport ABCG2 to design Novel Anticancer Drugs2007
- Author(s)
  Saito H, Hirano H, Ikegami Y, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Evidence for ubiquitinqtion and degradation of non-synonymous SNP proteins of human ATP-binding cassette transporter ABCG22007
- Author(s)
  Nakagawa H, Tamura A, Wakabayashi K, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] QSAR Analysis of Human ABC Transporter ABCB1 (P-GP/MDR1): Effect of SNPs on the Substrate Specificity toward CDK Inhibitors2007
- Author(s)
  Liew Ei Leen, Sakurai A, Hirano H, Seigneuret M, Ishikawa T
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Development of specific antibodies against mouse ATP-binding cassette transporter Abcg4 and expression of Abcg4 in Sf9 insect cells.2007
- Author(s)
  Koshiba S, Ito T, Ichinose H., Ishikawa, T.
- Organizer
  AACR Annual Meeting 2007
- Place of Presentation
  Los Angeles, U.S.A.
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Expression of ABC transporter mRNA in Cololectal cancer Specimen2007
- Author(s)
  Satake K, Ikegami Y, Sano K, Yamane Y, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Development of polyclonal antibodies specific to ATP-binding cassette transporters human ABCG4 and mouse Abcg4: Site-specific expression of mouse Abcg4 in brain2007
- Author(s)
  Koshiba S, Ito T, Wakabayashi K, Ichinose H, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] ヒトABCトランスポーターABCG2のポルフィリン輸送における薬理学的役割:薬物によるABCG2の阻害と光毒性との関係2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M.T, Ishikawa T.
- Organizer
  第34回ポルフィリン研究会
- Place of Presentation
  Los Angeles, U.S.A.
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Evaluation and Functional Classification of Nonsynonymous Single Nucleotide Polymorphisms of Human ABC Transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Ikegami Y, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Critical role of human ABC transporter ABCG2 in cancer photodynamic therapy and porphyria risk2007
- Author(s)
  Ishikawa T, Wakabayashi K, Saito H, Sakurai A, Tamara A
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Nrf2-dependent Induction of ABCC2 and ABCG2 in HepG2 cells under Oxidative Stress2007
- Author(s)
  Hagiya Y, Adachi T, Nakagawa H, Hoshijima K, Noguchi N, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Re-evalution and functional classification of nonsynonymous single nucleotide polymorphisms of human ABC transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Takeda M, Ikegami Y, Ishikawa T
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  金沢
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Critical Role of Human ABC Transporter ABCG2 in Cancer Photodynamic Therapy and Porphyria Risk2007
- Author(s)
  An R, Tamura A, Onishi Y, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Liver X receptor ligands include the expression of ATP-binding cassette transporter ABCG2 in human Hepatoma HepG2 cells2007
- Author(s)
  Adachi T, Nakagawa H, Hoshijima K, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Nrf2-dependent Induction of ABCC2 and ABCG2 in HepG2 cells under Oxidative Stress2007
- Author(s)
  Hagiya Y, Adachi T, Nakagawa H, Hoshijima K, Noguchi N, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Liver X receptor ligands include the expression of ATP-binding cassette transporter ABCG2 in human Hepatoma HepG2 cells2007
- Author(s)
  Adachi T, Nakagawa H, Hoshijima K, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Development of Expression system of A Novel Human ATP-Binding Cassette treansporter ABCC112007
- Author(s)
  Toyoda Y, Sakurai A, Yoshiura K, Miwa N, Niikawa N, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] ヒトABCトランスポーターABCG2のポルフィリン輸送における薬理学的役割:薬物によるABCG2の阻害と光毒性との関係2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M.T, Ishikawa T.
- Organizer
  第34回ポルフィリン研究会
- Place of Presentation
  Los Angeles, U.S.A.
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Evaluation and Functional Classification of Nonsynonymous Single Nucleotide Polymorphisms of Human ABC Transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Ikegami Y, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Disulfide Bond Formation Plays a Crucial Role in Protein Stability of Human ABCG22007
- Author(s)
  Ishikawa T, Wakabayashi K, Saito H, Sakurai A, Tamura A
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Disulfide Bond Formation Plays a Crucial Role in Protein Stability of Human ABCG22007
- Author(s)
  Ishikawa T, Wakabayashi K, Saito H, Sakurai A, Tamara A
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Disulfide Bond Formation Plays a Crucial Role in Protein Stability of Human ABCG22007
- Author(s)
  Wakabayashi K, Nakagawa H, Tamura A, Hoshijima K, Komada M, Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Transport Mechanism-Based Drug Molecular Design: High-Speed Screening and Quantitative SAR Analysis of ABC Transport ABCG2 to design Novel Anticancer Drugs2007
- Author(s)
  Saito H, Hirano H, Ikegami Y, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Expression of ABC transporter mRNA in Cololectal cancer Specimen2007
- Author(s)
  Satake K, Ikegami Y, Sano K, Yamane Y, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Nrf2-dependent and indepenndent transcriptional upregulation of ABCC1, ABCC2, ABCC3, and ABCG2 genes in HepG2 cells.2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M. T, Ishikawa T.
- Organizer
  AACR Annual Meeting 2007
- Place of Presentation
  Los Angeles, U.S.A
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Functional validation of genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1): The funtional impact of tetra-allelic SNPs 2677G>T,A, or C2007
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T,
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  金沢
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Development of Expression system of A Novel Human ATP-Binding Cassette treansporter ABCC112007
- Author(s)
  Toyoda Y, Sakurai A, Yoshiura K, Miwa N, Niikawa N, Ishikawa T.
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Critical role of human ABC transporter ABCG2 in cancer photodynamic therapy and porphyria risk2007
- Author(s)
  Ishikawa T, Wakabayashi K, Saito H, Sakurai A, Tamura A
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Re-evalution and functional classification of nonsynonymous single nucleotide polymorphisms of human ABC transporter ABCG22007
- Author(s)
  Tamura A, Wakabayashi K, Takeda M, Ikegami Y, Ishikawa T
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  金沢
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] International Standardization of the Methods for In-vitro Funtional Analysis of Drug Transporters2007
- Author(s)
  Ishikawa T
- Organizer
  8th International ISSX Meeting (Short Course2)
- Place of Presentation
  仙台
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Characterization and Classification of CDK Inhibitors by QSAR Analysis of Human ABC Transporter ABCG22007
- Author(s)
  Saito H, Hirano H, Hirono S, Tokushima D, Ishikawa T
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  仙台
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] ヒトABCトランスポーターABCG2のポルフィリン輸送における薬理学的役割:薬物によるABCG2の阻害と光毒性との関係2007
- Author(s)
  Adachi T, Nakagawa H, Chung I, Kuo M.T, Ishikawa T.
- Organizer
  第34回ポルフィリン研究会
- Place of Presentation
  東京
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Functional validation of genetic polymorphisms of ABCB1 (P-glycoprotein/MDR1): The funtional impact of tetra-allelic SNPs 2677G>T, A, or C2007
- Author(s)
  Sakurai A, Onishi Y, Liew Ei Leen, Hirano H, Sakurai M, Seigneuret M, Ishikawa T,
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  金沢
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] Functional Validate Nonsynonymous Polymorphisms of Human ABCB1 Transporter ABCB1 (P-glycoprotein/MDR1)2007
- Author(s)
  Sakurai A, Onishi Y, Hirano H, Liew Ei Leen, Obanayama K, Kim G, Sakurai M Ishikawa T
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Functionally Validate Nonsynonymous Polymorphisms of Human ABC Transporter ABCB1 (P-glycoprotein/MDR1)2007
- Author(s)
  Sakurai A, Tamura A, Saito H, Wakabayashi K, Sakaeda T, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18201041
[Presentation] Functionally Validate Nonsynonymous Polymorphisms of Human ABC Transporter ABCB1 (P-glycoprotein/MDR1)2007
- Author(s)
  Sakurai A, Tamura A, Saito H, Wakabayashi K, Sakaeda T, Ishikawa T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19659136
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、小金井美穂、吉田久博、藤城高広、木村誠吾、深見竹広、梶本宜永、宮武伸一、黒岩敏彦、石川智久
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子の発現調節
- Author(s)
  石川智久、梶本宜永、Wei Sun 、井上裕貴、池上洋二、萩谷祐一郎、小倉俊一郎、宮武伸一、黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Pharmacogenomics of Human ABC Transporters: From Bench to Bedside
- Author(s)
  Toshihisa Ishikawa
- Organizer
  Personalized Medicine in Cancer Treatment
- Place of Presentation
  中国Shenzhen
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Point-of-Care Technology for Personalized Medicine
- Author(s)
  Ishikawa T
- Organizer
  Bio-IT World & Molecular Med TRI-CON ASIA
- Place of Presentation
  Marina Bay Sands, Singapore, Singapore
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子発現の制御
- Author(s)
  石川智久、井上裕貴、池上洋二、中川大、黒岩敏彦
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、黒岩敏彦、石川智久
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 脳腫瘍幹細胞様細胞に対する5-ALA PDT感受性の評価
- Author(s)
  藤城高広、梶本宜永、木村誠吾、宮武伸一、石川智久、黒岩敏彦
- Organizer
  ポルフィリンALA学会
- Place of Presentation
  東京工業大学すずかけ台キャンパス
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] Pharmacogenomics of Drug Transporters and Clinical Applications
- Author(s)
  Ishikawa T
- Organizer
  The 2nd International Conference on Translational & Personalized Medicine
- Place of Presentation
  Holiday Inn Chicago-North Shore, Chicago, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-based photodynamic diagnosis of malignant brain tumor: Molecular design of ABCG2 inhibitors
- Author(s)
  Ishikawa T., Kuroiwa T.
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 5-Aminolevulinic Acid (ALA)-Based Photodynamic Therapy of Malignant Brain Tumors and Glioma Stem Cells: From Basic Research to Clinical Applications of an ABCG2 Inhibitor
- Author(s)
  Ishikawa T, Fujishiro T, Kajimoto Y, Inoue Y, Ikegami Y, Kuroiwa T.
- Organizer
  FEBS ATP-Binding Cassette (ABC) Proteins
- Place of Presentation
  Hotel Grauer Baer, Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の多剤耐性トランスポーターのファーマコゲノミクス：基礎研究から個別化医療に向けた新たな挑戦
- Author(s)
  石川智久
- Organizer
  愛媛大学医学部セミナー
- Place of Presentation
  愛媛大学医学部
- Invited
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] The role of Nrf2 in photodynamic therapy: Regulation of ABCG2 gene expression
- Author(s)
  Ishikawa T, Kajimoto Y, Inoue Y, Ikegami Y, Nakagawa Y, Kuroiwa Y
- Organizer
  日本生化学会 2013年次大会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍のALA光線力学診断・治療に向けて： In silico創薬分子デザインから臨床応用へ
- Author(s)
  石川智久
- Organizer
  第347回CBI学会研究講演会
- Place of Presentation
  東京大学本郷キャンパス・山上会館
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 癌の光線力学治療におけるNrf2の役割：ABCG2遺伝子発現の制御
- Author(s)
  石川智久、井上裕貴、池上洋二、中川大、黒岩敏彦
- Organizer
  日本薬物動態学会2013年総会
- Place of Presentation
  タワーホール船堀, 東京
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] 悪性脳腫瘍の光線力学診断と治療をめざしたABCG2阻害剤のデザイン
- Author(s)
  井上裕貴、池上洋二、佐野和美、黒岩敏彦、石川智久
- Organizer
  日本癌学会2013年総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] ポルフィリンを輸送するヒトABCトランスポーターABCG2の遺伝子多型：迅速SNP検出法の開発
- Author(s)
  櫻井亜季、Alexander Lezhava、林崎良英、石川智久
- Organizer
  第2回ポルフィリンALA学会
- Place of Presentation
  東京工業大学
- Data Source
  KAKENHI-PROJECT-23650619
[Presentation] New challenges in human ABC transporters research: From bench to clinical practice
- Author(s)
  Ishikawa T
- Organizer
  International Conference on Role of MDR proteins in pharmacokinetics and toxicology
- Place of Presentation
  Hotel Zamek Ryn, Ryn, Poland
- Invited
- Data Source
  KAKENHI-PROJECT-23650619

1. NAKAGAWA Hiroshi (40397039)

# of Collaborated Projects: 3 results

# of Collaborated Products: 93 results
2. KUROIWA Toshihiko (30178115)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
3. SODEOKA Mikiko (60192142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAKURAI Minoru (50162342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. DOI Takayuki (90212076)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANIGUCHI Naoyuki (90002188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SUGIYAMA Toshihiro (00127242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Kajimoto Yoshinaga (30224413)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 藤井茂 (60144482)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OGURA Shun-ichiro (90343160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
11. TERASAKI Tetsuya (60155463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKANAGA Hitomi (20284523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHTSUKI Sumio (60323036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HOSOYA Ken-ichi (70301033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ABE Takaaki (80292209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 鈴木正昭 (90093046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡辺恭良 (40144399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松田彰 (90157313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 伊藤誠二 (80201325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 萩原正敏 (10208423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 根岸学 (60201696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鈴木和年 (90162932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 影近弘之 (20177348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 米倉義晴 (60135572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 森望 (00130394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 橋本祐一 (90164798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 長野哲雄 (20111552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MORI Shinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 桜井実

# of Collaborated Projects: 0 results

# of Collaborated Products: 33 results
30. 遠藤良夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIKAWA Toshihisa 石川 智久

石川 智久

Research Projects

Research Products

Co-Researchers

Innovation of 5-ALA photodynamic diagnosis and treatment in malignant glioma by drug discovery and molecular design

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Development of equipment for next generation 5-ALA photodynamic diagnosis and treatment

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Photodynamic diagnosis of malignant brain tumor: analysis of molecular mechanisms and application to clinical diagnosisPrincipal Investigator

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ヒトABCトランスポーターの遺伝子多型を認識するタンパク品質管理機構の解明Principal Investigator

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Chemical biology targeting the brain : Molecular design of anticancer agents that efficiently attack brain tumorsPrincipal Investigator

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DRUG MOLECULAR DESIGN BASED ON THE FUNCTIONAL ANALYSIS OF DRUG TRANSPORTERSPrincipal Investigator

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生物新機能と創薬をめざす生体内分子科学

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Development of new drug screening system using the blood-brain barrier transporter gene expression

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癌化におけるスーパーオキサイドの役割

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Inactivation of Cu,Zn-superoxide dismutase due to glycation

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[Book] Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013

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[Book] Human ABC Transporter ABCC11. Ishikawa T, Konig J, Kim R. (eds.), Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013

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[Book] Emerging new technology of SNP typing. Ishikawa T, Konig J, Kim R. (eds.), Pharmacogenomics of Human Drug Transporters : Clinical Impacts2013

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[Book] Pharmacogenomics of Human Drug Transporters: Clinical Impacts2013

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Publisher

ISHIKAWA Toshihisa 石川智久

石川智久