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Itaka Keiji  位高 啓史

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… Alternative Names

ITAKA Keiji  位高 啓史

位高 敬史  イタカ ケイシ

位たか 啓史  イタカ ケイジ

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Researcher Number 60292926
Other IDs
External Links
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 教授
2025: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, ラボ長
2025: 大阪大学, 感染症総合教育研究拠点, 教授
Affiliation (based on the past Project Information) *help 2017 – 2024: 東京医科歯科大学, 生体材料工学研究所, 教授
2020: 東京大学, 大学院医学系研究科(医学部), 特任准教授
2016: 東京大学, 大学院医学系研究科(医学部), 特任准教授
2016: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), 主幹研究員
2016: 東京大学, 医学系研究科, 准教授 … More
2013 – 2016: 東京大学, 医学(系)研究科(研究院), 准教授
2015: 東京大学, 医学(系)研究科(研究院), 特任准教授
2015: 東京大学, 大学院医学系研究科, 特任准教授
2014: 東京大学, 医学系研究科, 特任准教授
2013: 東京大学, 大学院医学系研究科, 特任准教授
2011 – 2012: 東京大学, 医学(系)研究科(研究院), 特任准教授
2009 – 2012: The University of Tokyo, 大学院・医学系研究科, 特任准教授
2007 – 2008: The University of Tokyo, Graduate School of medicine, Lecturer
2006: The University of Tokyo, The graduate school of Medicine, Project Researcher, 大学院医学系研究科, 研究拠点特任教員
2005 – 2006: 東京大学, 大学院医学系研究科, 特任講師
2005: 東京大学, 大学院・医学系研究科, 研究拠点特任教員
2005: 東京大学, 大学院医学系研究科, 科学技術振興特任教員 Less
Review Section/Research Field
Principal Investigator
Biomedical engineering/Biomaterial science and engineering / Orthopaedic surgery / Biomedical engineering/Biological material science / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering / Basic Section 56020:Orthopedics-related / Neurosurgery
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Biomedical engineering/Biomaterial science and engineering / Orthopaedic surgery … More / Basic Section 90130:Medical systems-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Basic Section 53020:Cardiology-related / Cardiovascular medicine / Neurosurgery / Dermatology / Chemistry / Science and Engineering / General surgery / Biomedical engineering/Biological material science Less
Keywords
Principal Investigator
mRNA医薬 / mRNA / DDS / 変形性関節症 / 関節軟骨 / 脊髄損傷 / siRNA / ナノキャリア / 遺伝子治療 / ラマン分光法 … More / Catwalk / CatWalk / 運動機能評価 / 脳室内投与 / ネプリライシン / アルツハイマー病 / 転写因子 / mRNA送達 / 脳神経疾患 / 神経保護 / 脳虚血 / 難治神経疾患 / 神経疾患 / 送達システム / polyplex micelle / nanotechnology / bone and joint disease / nanocarrier / delivery system / 高分子ミセル / ナノテクノロジー / 骨軟骨疾患 / デリバリーシステム / 中枢神経系 / 免疫原性 / 神経障害 / ナノミセル / FGFシグナル / 生体適合性 / C型ナトリウム利尿ペプチド / スフェロイド / 遺伝子キャリア / 細胞移植 / 細胞治療 / 軟骨無形成症 / 外傷治療 / 骨格筋 / 外傷 / ナノ材料 / バイオテクノロジー / 遺伝子 / ナノバイオ … More
Except Principal Investigator
ハイドロゲル / siRNA / ドラッグデリバリー / mRNA / 後根神経節 / 神経障害性疼痛 / RNA / 統合インターフェース / 再生医工学 / 再生医療 / 遺伝子治療 / 高分子ミセル / サテライトグリア / マクロファージ / 末梢神経障害性疼痛 / ソノポレーション / 遺伝子導入 / 超音波 / ワクチン / 超音波治療装置 / 超音波穿孔法 / ウルトラファインバブル / ナノバブル / 超音波医科学 / キャリア / ゲノム編集 / 光制御 / 光増感剤 / 光化学的内在化 / PCI / 絞扼性神経モデル / 脊髄ミクログリア / ナノミセル / RNAシーケンス / 脊髄後角 / 細胞分化 / 直接変換 / RNA送達 / 直接分化転換 / 糖尿病 / ダイレクトリプログラミング / 体細胞 / インスリン / 1型糖尿病 / 分化転換 / 心筋疾患 / 核酸医療薬 / 蓄積病 / 核酸医療 / 遺伝性心筋症 / 遺伝性疾患 / 原因療法 / 核酸医薬 / 特発性心筋症 / 循環器・高血圧 / 原因治療 / 遺伝学 / 心筋症 / 循環器 / エクソソーム / 再生 / 細胞移植治療 / 白質障害 / 運動機能 / ネットワーク / 再現性 / 定位脳手術 / エンドセリン / 内包 / 大脳白質梗塞 / ラット / ドラッグデリバリーシステム / ヒト由来神経栄養因子 / ヒト骨髄由来細胞 / 白質障害モデル / 細胞移植 / ラット前脳虚血 / 脳梗塞実験モデル / 膿保護作用 / BDNF mRNA / 脳梗塞 / mRNA delivery / BDNFmRNA / 全脳虚血モデル / 二重盲検比較対照第II相試験 / 加工幹細胞SB623 / 骨髄由来間葉系幹細胞 / 大脳白質障害 / シグナル因子 / 生体材料 / 骨軟骨 / シグナル / 人工骨 / 骨軟骨生物学 / IL-17 / Th17 / ケモタキシス / 樹状細胞 / 血管成長因子 / 乾癬 / シグナル伝達 / 細胞・組織 / 発現制御 / 免疫学 / Transcription Factor / Joint Development / Cartilage Metabolism / ATX / HMG / GDF5 / WNT9A / 転写制御 / 転写因子 / 関節再生 / 骨軟骨代謝学 / differentiation / proliferation / 3D culture / soluble factor / hydrogel / chondrocyte / tissue engineering / nanotechnology / 分化 / 増殖 / 三次元培養 / 液性因子 / 軟骨細胞 / ナノテクノロジー / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / グルコーストランスポーター / アルツハイマー病 / 脳-血液関門 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / 血液脳関門(BBB) / 薬物送達システム / ポリアミノ酸 / ポリエチレングリコール / ブロック共重合体 / 血管再生 / 虚血性疾患 / 機能ポ性リマー / 機能性ポリマー / がん治療 Less
  • Research Projects

    (26 results)
  • Research Products

    (351 results)
  • Co-Researchers

    (51 People)
  •  光工学手法を応用した変形性関節症治療用mRNA医薬の創製Principal Investigator

    • Principal Investigator
      位高 啓史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Novel therapy targeting macrophages in neuropathic pain model

    • Principal Investigator
      平井 高志
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Photochemical internalization of mRNAs

    • Principal Investigator
      Ohtsuki Takashi
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Okayama University
  •  Development of a carrier-free transdermal nanobubble mRNA sonoporation transfer vaccine

    • Principal Investigator
      立花 克郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Fukuoka University
  •  Development of RNA therapies for curing of type 1 diabetes

    • Principal Investigator
      Matsumto Masahito
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Juntendo University
      Tokyo Medical and Dental University
  •  Novel therapy for neuropathic pain model based on mRNA agerts

    • Principal Investigator
      Hirai Takashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  mRNA medicine for treatment of osteoarthritis: An approach for chondrocytes in cartilage tissuePrincipal Investigator

    • Principal Investigator
      Itaka Keiji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Development and Evaluation of New Clinically Applicable Nucleic Acid Drugs for Myocardial Diseases

    • Principal Investigator
      Onoue Kenji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Nara Medical University
  •  Treatment of spinal cord injury using mRNA medicinePrincipal Investigator

    • Principal Investigator
      位高 啓史
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of 4-dimensional scaffold system that integrates signaling factors and 3-dimensional structural biomaterials

    • Principal Investigator
      Tei Yuichi
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo
  •  mRNA送達機能構造材料を用いた骨・軟骨再生法の開発に関する基礎的検討

    • Principal Investigator
      鄭 雄一
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo
  •  Basic research for regenerative medicine for white matter disorder in central nervous system

    • Principal Investigator
      Imai Hideaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      The University of Tokyo
  •  mRNA medicine for neuroprotection after cerebral ischemic attackPrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Development of mRNA medicine for treatment of neural diseases and injuryPrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Development of a new therapeutic strategy for cardiomyopathy by administration of mRNA

    • Principal Investigator
      Onoue Kenji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Nara Medical University
  •  治療用核酸頭蓋内送達システムの開発と脳神経系難病治療への展開Principal Investigator

    • Principal Investigator
      位高 啓史
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo
  •  Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Chemistry
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
      The University of Tokyo
  •  Induction of IL-17-producing T cells by VEGF-A as starting molecule: Paradigm shift of psoriasis pathogenesis.

    • Principal Investigator
      Tokura Yoshiki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Development of in vivo mRNA delivery system for treating diseasesPrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Gene therapy for achodroplasia using a biocompatible non-viral gene delivery systemPrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  A novel approach to treat severe trauma using gene introduction by nanomicelle into skeletal musclePrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of Novel Therapeutic Angiogenesis Method by Combination of Nanotechnology and siRNA Targeting PHD2

    • Principal Investigator
      NISHIYAMA Nobuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Development of multifunctional polymeric micelles for systemic siRNA delivery

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of multi-functional nanocarrier of siDNA and application for bone and joint diseasesPrincipal Investigator

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Expression Cloning of Joint Regenerative Genes

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
      The University of Tokyo
  •  Research and Development for Fabrication of 3D-structured Tissue-engineered Cartilage through Nino-molecular Technologies

    • Principal Investigator
      HOSHI Kazuto
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo

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All Journal Article Presentation Book Patent

  • [Book] 三次元培養における培養手法と周辺技術動向2019

    • Author(s)
      位髙啓史
    • Total Pages
      197
    • Publisher
      情報機構
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Book] 認知症の早期診断技術と進行抑制/予防薬・機能性食品の開発2019

    • Author(s)
      位髙啓史
    • Total Pages
      486
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Book] 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリー(トランスレーショナルリサーチを支援する遺伝子医学MOOK30号)2016

    • Author(s)
      内田智士、位高啓史、片岡一則
    • Pages
      119-124
    • Total Pages
      300
    • Publisher
      株式会社メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] Nanoparticles in the lung : environmental exposure and drug delivery(Drug and gene delivery in the lungs)2015

    • Author(s)
      S. Uchida, K. Itaka, K. Kataoka
    • Total Pages
      403
    • Publisher
      CRC press, Taylor & Francis Group(Florida, USA)
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] 口腔科学2013

    • Author(s)
      位高 啓史
    • Total Pages
      1072
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Book] バイオマテリアルとしての細胞:骨芽細胞.バイオマテリアルの基礎2010

    • Author(s)
      位高啓史
    • Publisher
      日本医学館
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Book] 医療ナノテクノロジー-最先端医学とナノテクの融合-(監修:片岡 一則)第II部第1章「ナノDDS」(pp.86-108)2007

    • Author(s)
      位高 啓史
    • Total Pages
      227
    • Publisher
      杏林図書
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] 医療ナノテクノロジー -最先端医学とナノテクの融合-(監修:片岡 一則) 第II部第1章「ナノDDS」2007

    • Author(s)
      位高 啓史
    • Publisher
      杏林図書
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] 高分子ナノキャリアを用いた遺伝子導入と再生医療への応用2007

    • Author(s)
      位高 啓史, 片岡 一則
    • Publisher
      メディカルレビュー(in press)
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] 高分子ミセル型ナノキャリアによるDDSとティッシュエンジニアリングへの応用2006

    • Author(s)
      位たか 啓史, 片岡 一則
    • Publisher
      日本医学館(In press)
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] ナノキャリアによる遺伝子・siRNAデリバリー2006

    • Author(s)
      位たか 啓史, 鄭 雄一, 片岡 一則
    • Total Pages
      400
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Intracranial Gene Delivery Mediated by Albumin-Based Nanobubbles and Low-Frequency Ultrasound2024

    • Author(s)
      Koga Takayuki、Kida Hiroshi、Yamasaki Yutaro、Feril Loreto B.、Endo Hitomi、Itaka Keiji、Abe Hiroshi、Tachibana Katsuro
    • Journal Title

      Nanomaterials

      Volume: 14 Issue: 3 Pages: 285-285

    • DOI

      10.3390/nano14030285

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K15728, KAKENHI-PROJECT-21K09168, KAKENHI-PROJECT-23K07800, KAKENHI-PROJECT-23K08835, KAKENHI-PROJECT-23K25235
  • [Journal Article] Novel Technique of Anterior Foraminotomy Based on Augmented Reality with Computed Tomography Navigation System: A Case Report2024

    • Author(s)
      Hirai Takashi、Egawa Satoru、Sakai Kenichiro、Onuma Hiroaki、Hashimoto Jun、Utagawa Kurando、Morishita Shingo、Yamada Kentaro、Matsukura Yu、Arai Yoshiyasu、Yoshii Toshitaka
    • Journal Title

      Spine Surgery and Related Research

      Volume: 8 Issue: 1 Pages: 114-117

    • DOI

      10.22603/ssrr.2023-0162

    • ISSN
      2432-261X
    • Year and Date
      2024-01-27
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08582
  • [Journal Article] Augmented Reality Support for Anterior Decompression and Fusion Using Floating Method for Cervical Ossification of the Posterior Longitudinal Ligament2023

    • Author(s)
      Onuma Hiroaki、Sakai Kenichiro、Arai Yoshiyasu、Torigoe Ichiro、Tomori Masaki、Sakaki Kyohei、Hirai Takashi、Egawa Satoru、Kobayashi Yutaka、Okawa Atsushi、Yoshii Toshitaka
    • Journal Title

      Journal of Clinical Medicine

      Volume: 12 Issue: 8 Pages: 2898-2898

    • DOI

      10.3390/jcm12082898

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08582
  • [Journal Article] Raman spectroscopic insight into osteoarthritic cartilage regeneration by mRNA therapeutics encoding cartilage-anabolic transcription factor Runx12022

    • Author(s)
      Pezzotti Giuseppe、Zhu Wenliang、Terai Yuki、Marin Elia、Boschetto Francesco、Kawamoto Komei、Itaka Keiji
    • Journal Title

      Materials Today Bio

      Volume: 13 Pages: 100210-100210

    • DOI

      10.1016/j.mtbio.2022.100210

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] Versatile Design of Intracellular Protein-Responsive Translational Regulation System for Synthetic mRNA2022

    • Author(s)
      Nakanishi Hideyuki、Saito Hirohide、Itaka Keiji
    • Journal Title

      ACS Synthetic Biology

      Volume: 11 Issue: 3 Pages: 1077-1085

    • DOI

      10.1021/acssynbio.1c00567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-19K20696, KAKENHI-PROJECT-20H05626
  • [Journal Article] Synthetic mRNA for ex?vivo therapeutic applications2022

    • Author(s)
      Nakanishi Hideyuki、Itaka Keiji
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 44 Pages: 100447-100447

    • DOI

      10.1016/j.dmpk.2022.100447

    • NAID

      210000173115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-19K20696
  • [Journal Article] mRNAを用いた新しい創薬の可能性2022

    • Author(s)
      位髙啓史
    • Journal Title

      実験医学

      Volume: 40 Pages: 550-556

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] Treatment of ischemic neuronal death by introducing brain-derived neurotrophic factor mRNA using polyplex nanomicelle2021

    • Author(s)
      Y. Fukushima, S. Uchida, H. Imai, H. Nakatomi, K. Kataoka, N. Saito, K. Itaka
    • Journal Title

      Biomaterials

      Volume: 270 Pages: 120681-120681

    • DOI

      10.1016/j.biomaterials.2021.120681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K18381
  • [Journal Article] Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice2021

    • Author(s)
      Oyama Natsuko、Kawaguchi Maho、Itaka Keiji、Kawakami Shigeru
    • Journal Title

      Pharmaceutics

      Volume: 13 Issue: 11 Pages: 1810-1810

    • DOI

      10.3390/pharmaceutics13111810

    • NAID

      120007185291

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-21H03818
  • [Journal Article] 新しい創薬モダリティとしてのmRNA2021

    • Author(s)
      位髙啓史
    • Journal Title

      BIO Clinica

      Volume: 35 Pages: 1371-1375

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] 新規創薬・ワクチンモダリティとしてのmRNA2021

    • Author(s)
      位髙啓史
    • Journal Title

      医学のあゆみ

      Volume: 279 Pages: 988-992

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬・mRNAワクチンとは何か2021

    • Author(s)
      位髙啓史
    • Journal Title

      学術の動向

      Volume: 26 Pages: 38-43

    • NAID

      130008163595

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬・mRNAワクチンの基礎と応用2021

    • Author(s)
      中西秀之、位髙啓史
    • Journal Title

      実験医学増刊号

      Volume: 39 Pages: 2693-2701

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬に利用されるキャリア開発:ナノミセル型キャリア2020

    • Author(s)
      位髙啓史
    • Journal Title

      Drug Delivery System

      Volume: 35 Pages: 27-34

    • NAID

      130007835773

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬の臨床展開2020

    • Author(s)
      位高啓史
    • Journal Title

      PHARMSTAGE

      Volume: 20 Pages: 65-68

    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA as a Tool for Gene Transfection in 3D Cell Culture for Future Regenerative Therapy2020

    • Author(s)
      S. Uchida, K. Yanagihara, A. Matsui, K. Kataoka, K. Itaka
    • Journal Title

      Micromachines

      Volume: 11 Issue: 4 Pages: 426-426

    • DOI

      10.3390/mi11040426

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-17K20086
  • [Journal Article] Regulation of Chondrocyte Differentiation by Changing Intercellular Distances Using Type II Collagen Microfibers2020

    • Author(s)
      Li Jinyu、Sasaki Naoko、Itaka Keiji、Terpstra Margo、Levato Riccardo、Matsusaki Michiya
    • Journal Title

      ACS Biomaterials Science & Engineering

      Volume: 6 Issue: 10 Pages: 5711-5719

    • DOI

      10.1021/acsbiomaterials.0c00427

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬開発の世界的動向2019

    • Author(s)
      位髙啓史、秋永士朗、井上貴雄
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス, PMDRS

      Volume: 50 Pages: 242-249

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬品の品質・安全性評価の考え方2019

    • Author(s)
      荒戸 照世, 位髙 啓史,秋永 士朗,佐藤 秀昭,山口 照英,真木 一茂,内田 恵理子,吉田 徳幸,井上 貴雄
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス, PMDRS

      Volume: 50 Pages: 300-306

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Journal Article] Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factor.2019

    • Author(s)
      C. -Y. Lin, S. T. Crowley, S. Uchida, Y. Komaki, K. Kataoka, K. Itaka
    • Journal Title

      Mol. Ther. Nucleic Acids

      Volume: 16 Pages: 162-171

    • DOI

      10.1016/j.omtn.2019.02.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17F17410, KAKENHI-PROJECT-16K10842, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-20K20386
  • [Journal Article] Enhancement of motor function 1 recovery after spinal cord injury in mice by delivery of brain derived neurotrophic factor mRNA.2019

    • Author(s)
      S. T. Crowley, Y. Fukushima, S. Uchida, K. Kataoka, K. Itaka
    • Journal Title

      Mol. Ther. Nucleic Acids

      Volume: 17 Pages: 465-476

    • DOI

      10.1016/j.omtn.2019.06.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-19K18381, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17F17410, KAKENHI-PROJECT-19H03776
  • [Journal Article] mRNA医薬の研究開発動向と将来展望2019

    • Author(s)
      位髙啓史
    • Journal Title

      医薬ジャーナル

      Volume: 55 Pages: 627-632

    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Journal Article] mRNA医薬の研究開発動向と将来展望2019

    • Author(s)
      位髙啓史
    • Journal Title

      医薬ジャーナル

      Volume: 55 Pages: 627-632

    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] Enhanced Antibacterial Property of Facet-Engineered TiO2 Nanosheet in Presence and Absence of Ultraviolet Irradiation2019

    • Author(s)
      Hayashi Kenichiro、Nozaki Kosuke、Tan Zhenquan、Fujita Kazuhisa、Nemoto Reina、Yamashita Kimihiro、Miura Hiroyuki、Itaka Keiji、Ohara Satoshi
    • Journal Title

      Materials

      Volume: 13 Issue: 1 Pages: 78-78

    • DOI

      10.3390/ma13010078

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11796, KAKENHI-PROJECT-18K17086, KAKENHI-PROJECT-16H05531, KAKENHI-PROJECT-16K11645, KAKENHI-PROJECT-19H03776
  • [Journal Article] Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination2018

    • Author(s)
      Uchida Satoshi、Yoshinaga Naoto、Yanagihara Kayoko、Yuba Eiji、Kataoka Kazunori、Itaka Keiji
    • Journal Title

      Biomaterials

      Volume: 150 Pages: 162-170

    • DOI

      10.1016/j.biomaterials.2017.09.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03024, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] mRNA医薬を用いた脳神経疾患の治療戦略2018

    • Author(s)
      位髙啓史、福島雄大
    • Journal Title

      バイオマテリアル-生体材料-

      Volume: 36 Pages: 220-223

    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Journal Article] Combined CatWalk Index: an improved method to measure mouse motor function using the automated gait analysis system2018

    • Author(s)
      Crowley S, Kataoka K, Itaka K
    • Journal Title

      BMC Research Notes

      Volume: 11 Issue: 1 Pages: 263-263

    • DOI

      10.1186/s13104-018-3374-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-17F17410
  • [Journal Article] Treatment of Bone Defects by Transplantation of Genetically Modified Mesenchymal Stem Cell Spheroids2018

    • Author(s)
      Yanagihara K, Uchida S, Ohba S, Kataoka K, Itaka K
    • Journal Title

      Molecular Therapy - Methods & Clinical Development

      Volume: 9 Pages: 358-366

    • DOI

      10.1016/j.omtm.2018.04.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15642, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K19635
  • [Journal Article] mRNA医薬を用いた脳神経疾患の治療戦略2018

    • Author(s)
      位髙啓史、福島雄大
    • Journal Title

      バイオマテリアル-生体材料-

      Volume: 36 Pages: 220-223

    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] mRNA医薬を用いた脳神経疾患の治療戦略2018

    • Author(s)
      位髙啓史、福島雄大
    • Journal Title

      バイオマテリアル-生体材料-

      Volume: 36 Pages: 220-223

    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Journal Article] Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection.2018

    • Author(s)
      A. Matsui, S. Uchida, A. Hayashi, K. Kataoka, K. Itaka
    • Journal Title

      J. Control. Release

      Volume: 285 Pages: 1-11

    • DOI

      10.1016/j.jconrel.2018.06.033

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-15H03017
  • [Journal Article] Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer.2017

    • Author(s)
      F. Perche, S. Uchida, H. Akiba, C.-Y. Lin, M. Ikegami, A. Disrala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka
    • Journal Title

      Curr. Alzheimer Res.

      Volume: 14 Issue: 3 Pages: 295-302

    • DOI

      10.2174/1567205013666161108110031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H02420
  • [Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017

    • Author(s)
      Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 2001-2009

    • DOI

      10.1038/s41467-017-00952-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Screening of mRNA chemical modification to maximize protein expression with reduced immunogenicity.2016

    • Author(s)
      S. Uchida, K. Kataoka, K. Itaka
    • Journal Title

      Pharmaceutics

      Volume: 7 Issue: 3 Pages: 137-151

    • DOI

      10.3390/pharmaceutics7030137

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Introduction to Special Issue: A New Paradigm of Gene Therapy2016

    • Author(s)
      Itaka K
    • Journal Title

      Pharmaceutics

      Volume: 8 Issue: 1 Pages: 1-1

    • DOI

      10.3390/pharmaceutics8010001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles2016

    • Author(s)
      Lin CY, Perche F, Ikegami M, Uchida S, Kataoka K, Itaka K
    • Journal Title

      J Control Release

      Volume: 235 Pages: 268-275

    • DOI

      10.1016/j.jconrel.2016.06.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14F04406, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure.2016

    • Author(s)
      H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 138 Issue: 5 Pages: 1478-1481

    • DOI

      10.1021/jacs.5b11726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Development of mRNA-based therapeutics2016

    • Author(s)
      Itaka K
    • Journal Title

      Nihon Yakurigaku Zasshi

      Volume: 148 Pages: 190-196

    • NAID

      130005598209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids2016

    • Author(s)
      Uchida S, Hayakawa K, Ogata T, Tanaka S, Kataoka K, Itaka K
    • Journal Title

      Biomaterials

      Volume: 109 Pages: 1-11

    • DOI

      10.1016/j.biomaterials.2016.09.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-15K20962
  • [Journal Article] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.2016

    • Author(s)
      1.Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 18743-18743

    • DOI

      10.1038/srep18743

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330
  • [Journal Article] Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety.2016

    • Author(s)
      S. Uchida, H. Kinoh, T. Ishii, A. Matsui, T. A. Tockary, K. M. Takeda, H. Uchida, K. Osada, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 82 Pages: 221-228

    • DOI

      10.1016/j.biomaterials.2015.12.031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
  • [Journal Article] メッセンジャーRNA医薬を実現するDDS開発と疾患治療への応用2016

    • Author(s)
      位髙啓史
    • Journal Title

      Drug Delivery System (DDS)

      Volume: 31 Pages: 343-351

    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases.2015

    • Author(s)
      A. Matsui, S. Uchida, T. Ishii, K. Itaka, K. Kataoka
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 15810-15810

    • DOI

      10.1038/srep15810

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury.2015

    • Author(s)
      Hayakawa K, Uchida S, Ogata T, Tanaka S, Kataoka K, Itaka K.
    • Journal Title

      J Control Release

      Volume: 197 Pages: 1-9

    • DOI

      10.1016/j.jconrel.2014.10.027

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle2015

    • Author(s)
      Chen Q, Osada K, Pennisi M, Uchida S, Tockary TA, Dirisala A, Li Y, Takeda KM, Oniyanagi S, Itaka K, Kataoka K
    • Journal Title

      Soft Matter

      Volume: 11 Issue: 14 Pages: 2718-2722

    • DOI

      10.1039/c4sm02850c

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Toroidal packaging of pDNA into block ionomer micelles exerting promoted in vivo gene expression.2015

    • Author(s)
      Y. Li, K. Osada, Q. Chen, T. A. Tockary, A. Dirisala, K. M. Takeda, S. Uchida, K. Nagata, K. Itaka, K. Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 16 Issue: 9 Pages: 2664-2671

    • DOI

      10.1021/acs.biomac.5b00491

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
  • [Journal Article] ナノDDSの再生医療への展開:mRNAデリバリーによる生体内細胞制御2015

    • Author(s)
      位髙啓史,片岡一則
    • Journal Title

      細胞工学

      Volume: 34 Pages: 946-951

    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Journal Article] Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles2015

    • Author(s)
      Baba M, Itaka K, Kondo K, Yamasoba T, Kataoka K.
    • Journal Title

      J Control Release

      Volume: 201 Pages: 41-48

    • DOI

      10.1016/j.jconrel.2015.01.017

    • NAID

      120006348466

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-26293366
  • [Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors2014

    • Author(s)
      Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 10 Pages: 3416-3426

    • DOI

      10.1016/j.biomaterials.2013.12.086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
  • [Journal Article] Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors2014

    • Author(s)
      Dirisala A, Osada K, Chen Q, Tockary TA, Machitani K, Osawa S, Liu X, Ishii T, Miyata K, Oba M, Uchida S, Itaka K, Kataoka K
    • Journal Title

      Biomaterials

      Volume: 35(20) Issue: 20 Pages: 5359-5368

    • DOI

      10.1016/j.biomaterials.2014.03.037

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.2014

    • Author(s)
      Nagata K, Itaka K, Baba M, Uchida S, Ishii T, Kataoka K.
    • Journal Title

      J Control Release

      Volume: 183C Pages: 27-34

    • DOI

      10.1016/j.jconrel.2014.03.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection2014

    • Author(s)
      H. Uchida, K. Itaka, T. Nomoto, T. ishii, T. Suma, M. Ikegami, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 136 Issue: 35 Pages: 12396-12405

    • DOI

      10.1021/ja506194z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006
  • [Journal Article] An injectable spheroid system with genetic modification for cell transplantation therapy2014

    • Author(s)
      Satoshi Uchida, Keiji Itaka, Takahifo Nomoto, Taisuke Endo, Yu Matsumoto, Takehiko Ishii, Kazunori Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Pages: 2499-2506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Journal Article] Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.2013

    • Author(s)
      Ohgidani M, Furugaki K, Shinkai K, Kunisawa Y, Itaka K, Kataoka K, Nakano K.
    • Journal Title

      J Control Release

      Volume: 167 Issue: 3 Pages: 238-247

    • DOI

      10.1016/j.jconrel.2013.02.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24390303, KAKENHI-PROJECT-24390322
  • [Journal Article] In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle2013

    • Author(s)
      Satoshi Uchida, Keiji Itaka, et al.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 2 Pages: e56220-e56220

    • DOI

      10.1371/journal.pone.0056220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Journal Article] Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers2013

    • Author(s)
      Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
    • Journal Title

      Macromolecules

      Volume: 46 Issue: 16 Pages: 6585-6592

    • DOI

      10.1021/ma401093z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain2012

    • Author(s)
      T.Suma, N.Nishiyama, et al
    • Journal Title

      Biomaterials

      Volume: 33 Issue: 9 Pages: 2770-2779

    • DOI

      10.1016/j.biomaterials.2011.12.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] 生体適合性遺伝子ナノキャリアの開発研究と疾患治療への応用.2012

    • Author(s)
      位高啓史
    • Journal Title

      バイオマテリアル-生体材料

      Volume: Vol.30 Pages: 39-46

    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles2011

    • Author(s)
      H.Uchida, N.Nishiyama, et al
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 133 Issue: 39 Pages: 15524-15532

    • DOI

      10.1021/ja204466y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Combination of Chondroitin Sulfate and Polyplex Micelles from Poly(ethylene glycol)-poly{ N'-[ N-(2-aminoethyl)-2-aminoethyl] aspartamide} Block Copolymer for Prolonged In Vivo Gene Transfection with Reduced Toxicity2011

    • Author(s)
      Uchida S, Itaka K, Chen Q, Osada K, Miyata K, Ishii T, Harada-Shiba M, Kataoka K
    • Journal Title

      J Control Release

      Volume: Vol.2 Pages: 296-302

    • URL

      http://dx.doi.org/10.1016/j.jconrel.2011.04.026

    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Combination of Chondroitin Sulfate and Polyplex Micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} Block Copolymer for Prolonged In Vivo Gene Transfection with Reduced Toxicity2011

    • Author(s)
      Uchida S, Itaka K, Chen Q, Osada K, Miyata K, Ishii T, Harada-Shiba M, Kataoka K
    • Journal Title

      J Control Release

      Volume: 2 Issue: 2 Pages: 296-302

    • DOI

      10.1016/j.jconrel.2011.04.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049
  • [Journal Article] Progress and prospects of polyplex nanomicelles for plasmid DNA delivery2011

    • Author(s)
      Itaka K, Kataoka K
    • Journal Title

      Curr Gene Ther

      Volume: Vol.11 Pages: 457-465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      J.Control. Release

      Volume: 143 Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity2010

    • Author(s)
      Itaka K, Ishii T, Hasegawa Y, Kataoka K.
    • Journal Title

      Biomaterials. 31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      Itaka K, Osada K, Morii K, Kim P, Yun SH, Kataoka K
    • Journal Title

      J Control Release

      Volume: Vol.143 Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      Itaka K, Osada K, Morii K, Kim P, Yun SH, Kataoka K.
    • Journal Title

      J Control Release. 143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-12010

    • Author(s)
      Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K
    • Journal Title

      Mol Pharm

      Volume: Vol.7 Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] バイオマテリアルとしての細胞:骨芽細胞2010

    • Author(s)
      位高啓史
    • Journal Title

      バイオマテリアルの基礎

      Pages: 233-236

    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010

    • Author(s)
      K. Miyata, N. Gouda, H. Takemoto, M. Oba, Y. Lee, H. Koyama, Y. Yamasaki, K. Itaka, N. Nishiyama, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 31(17) Issue: 17 Pages: 4764-4770

    • DOI

      10.1016/j.biomaterials.2010.02.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M. Oba, Y. Vachutinsky, K. Miyata, M. R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
    • Journal Title

      Mol. Pharm

      Volume: 7(2) Issue: 2 Pages: 501-509

    • DOI

      10.1021/mp9002317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22390244
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      K.Itaka, K.Kataoka, et al
    • Journal Title

      J.Control.Release Vol.143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity2010

    • Author(s)
      Itaka K, Ishii T, Hasegawa Y, Kataoka K
    • Journal Title

      Biomaterials

      Volume: Vol.31 Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-1.2010

    • Author(s)
      Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K
    • Journal Title

      Mol Pharm. (掲載確定,印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimising cumulative toxicity2010

    • Author(s)
      K.Itaka, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effectivegene carrier minimizing cumulative toxicity.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Efficient delivery of bioactive antibodies into thecytoplasm of living cells by charge-conversional polyion complex micelles. Angew2010

    • Author(s)
      Y. Lee, T. Ishii, H.-J. Kim, N. Nishiyama, Y. Hayakawa, K. Itaka, K. Kataoka
    • Journal Title

      Chem. Int. Ed

      Volume: 49(14) Issue: 14 Pages: 2552-2555

    • DOI

      10.1002/anie.200905264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats2009

    • Author(s)
      M. Harada-Shiba, I. Takamisawa, K. Miyata, T. Ishii, N. Nishiyama, K. Itaka, K. Kangawa, F. Yoshihara, Y. Asada, K. Hatakeyama, N. Nagaya, K. Kataoka
    • Journal Title

      Mol. Ther

      Volume: 17(7) Issue: 7 Pages: 1180-1186

    • DOI

      10.1038/mt.2009.63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299
  • [Journal Article] PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors2008

    • Author(s)
      Takae S, Itaka K, et a1
    • Journal Title

      J. Am Chem Soc 130

      Pages: 6001-6009

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomersas Bioresponsive Non-Viral Gene Vectors2008

    • Author(s)
      Takae S, Itaka K, et. al.
    • Journal Title

      J Am Chem Soc 130

      Pages: 6001-6009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors2008

    • Author(s)
      Takae S, Itaka K, et. al.
    • Journal Title

      J Am Chem Soc. 130(18)

      Pages: 6001-6009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] pH-Responsive PEGylated nanogels as targetable and low invasive endosomolytic agents to induce the enhanced transfection efficiency of nonviral gene vectors.2007

    • Author(s)
      Motoi Oishi, Keiji Itaka, et al.
    • Journal Title

      Colloid and Polymer Science (in press)

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Nano Bioengineering (Editor; Kazunori Kataoka) Chapter 2(1)2007

    • Author(s)
      Itaka K
    • Journal Title

      Kyorin Tosho

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Gene delivery with biocompatible cationic polymer : Pharmacogenomic analysis on cell bioactivity2007

    • Author(s)
      Masago K, Itaka K, et. al.
    • Journal Title

      Biomaterials 28(34)

      Pages: 5169-5175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner2007

    • Author(s)
      Ohba S, Itaka K, et. al.
    • Journal Title

      Biochem Biophys Res Commun. 15 357(4)

      Pages: 854-860

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomice2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15

      Pages: 1655-1662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Itaka K, et. al.
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-390

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Gene delivery with biocompatible cationic polymer:Pharmacogenomic analysis on cell bioactivity2007

    • Author(s)
      Masago K, Itaka K, et. al.
    • Journal Title

      Biomaterials. 28

      Pages: 5169-5175

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Itaka K, et. al.
    • Journal Title

      Biochem Biophys Res Commun 357(2)

      Pages: 383-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner2007

    • Author(s)
      Ohba S, Itaka K, et. al.
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 854-860

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly(ethylene glycol)-siRNA Conjugate Formulated in PEGylated Polyplexes2007

    • Author(s)
      Oishi M, Itaka K, et. al.
    • Journal Title

      Chem Med Chem 2(9)

      Pages: 1290-1297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] pH-Responsive PEGylated nanogels as targetable and low invasive endosomolytic agents to induce the enhanced transfection effciency of nonviral gene vectors2007

    • Author(s)
      Oishi M, Itaka K, et. al.
    • Journal Title

      Colloid Polym Sci 285

      Pages: 1055-1060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Gene delivery with biocompatible cationic polymer:Pharmacogenomic analysis on cell bioac2007

    • Author(s)
      Masago K, Itaka K, et. al.
    • Journal Title

      Biomaterials 28

      Pages: 5169-5175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] pH-Responsive PEGylated nanogels as targetable and low invasive endosomolytic agents to induce the enhanced transfection efficiency of nonviral gene vectors2007

    • Author(s)
      Oishi M, Itaka K, et. al.
    • Journal Title

      Colloid Polym Sci 285

      Pages: 1055-1060

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner2007

    • Author(s)
      Shinsuke Ohba, Keiji Itaka, et al.
    • Journal Title

      BBRC (in press)

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly (ethylene glycol)-siRNA Conjugate Formulated in PEGylated Polyplexes2007

    • Author(s)
      Oishi M, Itaka K, et. al.
    • Journal Title

      ChemMedChem 2

      Pages: 1290-1297

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly(ethvlene glvcol)-siRNA Coniugate Formulated in PEGylated Polyplexes2007

    • Author(s)
      Oishi M, Itaka K, et. al.
    • Journal Title

      Chem Med Chem 10

      Pages: 1290-1297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatibli polyplex nanomicelles2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15(9)

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] The State of the Art of Nanobioscience in Japan2006

    • Author(s)
      S.Ueno, K.Itaka et al.
    • Journal Title

      IEEE Trans Nanobiosci. 5(1)

      Pages: 54-65

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] A PEG-Based Biocompatible Block Catiomer with High Buffering Capacity for the Construction of Polyplex Micelles Showing Efficient Gen Transfer toward Primary Cells2006

    • Author(s)
      Kanayama N, Itaka K, et. al.
    • Journal Title

      Chem Med Chem 1(4)

      Pages: 439-444

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] PEG-based biocompatible block catiomer with high-buffering capacity for the construction of polyplex micells showing efficient gene transfer toward primary cells.2006

    • Author(s)
      N.Kanayama, K.Itaka, et al.
    • Journal Title

      ChemMedChem (in press)

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] The State of the Art of Nanobioscience in Japan2006

    • Author(s)
      Ueno S, Itaka K, et. al.
    • Journal Title

      IEEE Trans. NanoBiosci 5

      Pages: 54-65

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] A PEG-Based Biocompatible Block Catiomer with High Buffering Capacity for the Construction of Polyplex Micelles Showing Efficient Gene Transfer toward Primary Cells.2006

    • Author(s)
      Kanayama N, Itaka K, et. al.
    • Journal Title

      Chem Med Chem 1

      Pages: 439-444

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] The State of the Art of Nanobioscience in Japan2006

    • Author(s)
      Ueno S, Itaka K, et. al.
    • Journal Title

      IEEE Trans. NanoBiosci 5(1)

      Pages: 54-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      Nishiyama N, Itaka K, et. al.
    • Journal Title

      Nat Mater 4(12)

      Pages: 934-941

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      Nishiyama N, Itaka K, et. al.
    • Journal Title

      Nat Mater 4

      Pages: 934-941

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      N.Nishiyama, K.Itaka, et al.
    • Journal Title

      Nat. Mater. 4(12)

      Pages: 934-941

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing2004

    • Author(s)
      Itaka K et al.
    • Journal Title

      J Am Chem Soc. 126(42)

      Pages: 13612-13613

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390431
  • [Journal Article] Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing2004

    • Author(s)
      Itaka K et al.
    • Journal Title

      J Am Chem Soc 126(42)

      Pages: 13612-13613

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390431
  • [Patent] 軟骨変性の分析装置、これを含む診断または診断補助 のための装置、軟骨の変性程度を判定する方法、およ び被験物質の薬効を評価する方法2022

    • Inventor(s)
      位髙啓史
    • Industrial Property Rights Holder
      位髙啓史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Patent] 軟骨変性の分析装置、これを含む診断または診断補助のための装置、軟骨 の変性程度を判定する方法、および被験物質の薬効を評価する方法2021

    • Inventor(s)
      位髙啓史
    • Industrial Property Rights Holder
      位髙啓史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Patent] mRNA輸送担体の安定化方法2016

    • Inventor(s)
      内田 智士、片岡 一則、吉永 直人、位高 啓史
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-252488
    • Filing Date
      2016-12-27
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Patent] mRNAを効率よく生体内に送達できるポリイオンコンプレックス並びにこれを用いた関節症の治療薬および治療法2015

    • Inventor(s)
      位髙啓史,大庭伸介,鄭雄一,片岡一則
    • Industrial Property Rights Holder
      位髙啓史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-151564
    • Filing Date
      2015-07-31
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Patent] タンパク質発現を向上させる方法およびタンパク質発現用組成物2014

    • Inventor(s)
      位髙啓史,片岡一則,池上賢,内田智士,内田寛邦,長田和也
    • Industrial Property Rights Holder
      一般社団法人医療産業イノベーション機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-090634
    • Filing Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Patent] タンパク質発現を向上させる方法およびタンパク質発現用組成物2014

    • Inventor(s)
      位髙啓史, 片岡一則, 池上賢, 内田智士, 内田寛邦, 長田和也
    • Industrial Property Rights Holder
      一般社団法人医療産業イノベーション機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-090634
    • Filing Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Patent] mRNA送達用組成物2014

    • Inventor(s)
      片岡一則、位高啓史、石井武彦、内田寛邦、内田智士、馬場美雪
    • Industrial Property Rights Holder
      一般社団法人医療産業イノベーション機構
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-02-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Patent] mRNA送達用組成物2014

    • Inventor(s)
      片岡一則、位高啓史、石井武彦、内田寛邦、内田智士、馬場美雪
    • Industrial Property Rights Holder
      一般社団法人医療産業イノベーション機構
    • Filing Date
      2014-02-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Patent] ポリカチオン荷電性ポリマー及び核酸のキャリヤーとしての使用2006

    • Inventor(s)
      位高 啓史 他7名
    • Industrial Property Rights Holder
      位高 啓史 他7名
    • Industrial Property Number
      2005-035233
    • Filing Date
      2006-02-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Patent] ペプチドリガンドを有するブロック共重合体2005

    • Inventor(s)
      位たか 啓史他5名
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2005-054260
    • Filing Date
      2005-02-28
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Patent] ポリカチオン荷電性ポリマー及び核酸のキャリヤーとしての使用2005

    • Inventor(s)
      位たか 啓史他7名
    • Industrial Property Rights Holder
      東京大学
    • Industrial Property Number
      2005-035233
    • Filing Date
      2005-02-10
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] メッセンジャーRNA(mRNA)を用いた新しい創薬・遺伝子治療2022

    • Author(s)
      位髙啓史
    • Organizer
      第131回SCE・Net技術懇談会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の骨格筋へのハイドロダイナミクス法投与と末梢神経損傷治療への応用2022

    • Author(s)
      高橋拓也、福島雄大、位髙啓史
    • Organizer
      第21回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA創薬:ワクチン・医薬品への新展開2022

    • Author(s)
      位髙啓史
    • Organizer
      2022ライフサイエンス知財フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬・mRNAワクチンの過去・現在・未来2021

    • Author(s)
      位髙啓史
    • Organizer
      第36回Wakoワークショップ
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の神経保護治療応用:ナノミセルを用いたBDNF mRNAによる全脳虚血後海馬神経細胞死治療2021

    • Author(s)
      福島雄大,今井英明,中冨浩文,齊藤延人,位髙啓史
    • Organizer
      第80回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA 医薬・mRNA ワクチンによる新しい創薬の可能性2021

    • Author(s)
      位髙啓史
    • Organizer
      第11回CSJ化学フェスタ2021(日本化学会秋季事業)
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA 医薬・mRNA ワクチン開発と実用化2021

    • Author(s)
      位髙啓史
    • Organizer
      遺伝子・デリバリー研究会第20回シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の実用化に必要とされるDDS2021

    • Author(s)
      位髙啓史
    • Organizer
      第7回日本筋学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] 標的タンパク質を発現する細胞選択的にmRNA の翻訳を制御する技術の開発2021

    • Author(s)
      中西秀之、齊藤博英、位髙啓史
    • Organizer
      遺伝子・デリバリー研究会第20回シンポジウム
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNAs Encoding Split Cytotoxic Proteins for Selective Cell Elimination Based on Specific Protein Detection2021

    • Author(s)
      Kendall Free, Hideyuki Nakanishi, Keiji Itaka
    • Organizer
      9th International mRNA Health Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬を用いた新しい遺伝子治療の可能性2021

    • Author(s)
      位髙啓史
    • Organizer
      第24回日本ムコ多糖症研究会・日本ムコ多糖症患者家族の会 合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬品の開発と応用2021

    • Author(s)
      位髙啓史
    • Organizer
      第62回日本先天代謝異常学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA medicine and mRNA vaccine: A new drug modality for various diseases2021

    • Author(s)
      Keiji Itaka
    • Organizer
      14th International Symposium on Nanomedicine (ISNM 2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の現状と今後の展望2021

    • Author(s)
      位髙啓史
    • Organizer
      ロシュWebinar
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬・ワクチンとは何か2021

    • Author(s)
      位髙啓史
    • Organizer
      日本薬学会・日本学術会議共同主催 公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNAワクチン・mRNA医薬品とは何か?2021

    • Author(s)
      位髙啓史
    • Organizer
      日本学術会議 公開シンポジウム「新型コロナワクチンを正しく知る」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬品の実用2021

    • Author(s)
      位髙啓史
    • Organizer
      一般財団法人製剤機械技術学会 第31回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNAワクチン・mRNA医薬の開発と今後の展望2021

    • Author(s)
      位髙啓史
    • Organizer
      第37回日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬・mRNAワクチンの開発と今後の課題2021

    • Author(s)
      位髙啓史
    • Organizer
      第85回日本皮膚科学会東京支部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] 腎臓を標的とするmRNA送達の基礎的検討2020

    • Author(s)
      川上茂、大山奈津子、川口真帆、位髙啓史
    • Organizer
      第36回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNAで拓く未来医学2020

    • Author(s)
      位髙啓史
    • Organizer
      未来医学研究会マンスリーセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬開発と難治疾患治療・再生医療への応用2020

    • Author(s)
      位髙啓史
    • Organizer
      第20回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics: A new modality for treatment of bone and joint diseases2020

    • Author(s)
      Keiji Itaka
    • Organizer
      Japan Bone Academy 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics for regulating cell fate and functions2020

    • Author(s)
      Keiji Itaka
    • Organizer
      第43回日本分子生物学会年会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] Intraventricular BDNF mRNA administration prevents ischemic neuronal death with the uptake predominantly by astrocytes2020

    • Author(s)
      Yuta Fukushima, Keiji Itaka
    • Organizer
      8th International mRNA Health Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics: from vaccine to regenerative medicine2020

    • Author(s)
      位髙啓史
    • Organizer
      COINS Seminar #57
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の可能性~ワクチンから再生医療まで2020

    • Author(s)
      位髙啓史
    • Organizer
      時事トップセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] Conditional transitional regulation of synthetic mRNAs by caliciviral VPg protein-based translational activator (CaVT)2020

    • Author(s)
      Hideyuki Nakanishi, Keiji Itaka, Hirohide Saito
    • Organizer
      8th International mRNA Health Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬実用化に向けた展望2020

    • Author(s)
      位髙啓史
    • Organizer
      第22回インターフェックスジャパン
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の現状と将来展望2020

    • Author(s)
      位髙啓史
    • Organizer
      ウェビナー「mRNA創薬の最前線」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬開発と難治疾患治療・再生医療への応用2020

    • Author(s)
      位髙啓史
    • Organizer
      ナノ学会第18回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の関節・軟骨疾患治療への応用2019

    • Author(s)
      位髙啓史、福島雄大、松本征仁
    • Organizer
      第6回JCRベーシックリサーチカンファレンス
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics for intractable diseases and regenerative medicine2019

    • Author(s)
      Keiji Itaka
    • Organizer
      Seoul Brain Barrier Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] Muscle-targeted hydrodynamic injection of mRNA medicine for treating peripheral nerve injury2019

    • Author(s)
      Fumiya Ebihara, Kazuya Nagata, Yuta Fukushima, Masahito Matsumoto, Keiji Itaka
    • Organizer
      19th Symposium for Gene Design and Delivery
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] メッセンジャーRNA(mRNA)医薬を用いた椎間板疾患治療2019

    • Author(s)
      位髙啓史、Chin-yu Lin, Samuel Crowley、内田智士、小牧裕司、片岡一則
    • Organizer
      第34回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA medicine for introducing therapeutic transcription factors2019

    • Author(s)
      Keiji Itaka
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA医薬が生み出す新しい治療戦略2019

    • Author(s)
      位髙啓史
    • Organizer
      第3回バイオ医薬EXPO
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] 核酸医薬・mRNA医薬実用化に求められるDDS2019

    • Author(s)
      位髙啓史
    • Organizer
      日本核酸医薬学会第5回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬が生み出す新しい治療戦略2019

    • Author(s)
      位髙啓史
    • Organizer
      第3回バイオ医薬EXPO「次世代の核酸医薬・遺伝子治療の可能性」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA medicine encoding a cartilage-anabolic transcription factor for treatment of intervertebral disc disease2019

    • Author(s)
      Keiji Itaka, Chin-yu Lin, Samuel Crowley, Satoshi Uchida, Yuji Komaki, Kazunori Kataoka
    • Organizer
      日本核酸医薬学会第5回年会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] In vivo Delivery of mRNA Therapeutics by unique polyplex nanomicelles2019

    • Author(s)
      Tetsuo Yoshida, Miki Masai, Satoshi Uchida, Shiro Akinaga, Kazunori Kataoka, Keiji Itaka
    • Organizer
      7th International mRNA Health Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の運動器疾患治療への応用2019

    • Author(s)
      位髙啓史
    • Organizer
      日本筋学会第5回学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA医薬の脳神経保護薬への展開:BDNF mRNAのナノミセルによる脳室内投与2019

    • Author(s)
      福島雄大、内田智士、片岡一則、位髙啓史
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬による虚血性中枢神経疾患神経保護治療2019

    • Author(s)
      福島雄大,位髙啓史
    • Organizer
      第4回日本遺伝子細胞治療学会若手研究会セミナー
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の再生医療への応用2019

    • Author(s)
      位髙啓史
    • Organizer
      第35回日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA 医薬の開発と難治疾患治療への応用2019

    • Author(s)
      位髙啓史
    • Organizer
      第7回お茶の水サイエンス倶楽部
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics for intractable diseases and regenerative medicine2019

    • Author(s)
      Keiji Itaka
    • Organizer
      2019 Seoul Brain Barrier Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA医薬の骨格筋への投与による末梢神経障害の早期機能回復2019

    • Author(s)
      蛯原郁弥、長田和也、福島雄大、松本征仁、位髙啓史
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] BDNF mRNA therapeutics for ischemic neuronal death2019

    • Author(s)
      Yuta Fukushima, Satoshi Uchida, Kazunori Kataoka, Keiji Itaka
    • Organizer
      7th International mRNA Health Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] 骨格筋を標的とするmRNA医薬の開発と末梢神経障害治療への応用2019

    • Author(s)
      蛯原郁弥、長田和也、福島雄大、松本征仁、位髙啓史
    • Organizer
      第41回日本バイオマテリアル学会大会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の再生医療への応用2019

    • Author(s)
      位髙啓史
    • Organizer
      第35回日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] Design, Characterisation And Optimisation Of Novel Polymeric Nanoparticle Systems For Intratumoral Delivery Of Messenger RNA2019

    • Author(s)
      Sanyogitta Puri, Masai M, Akinaga S, Itaka K
    • Organizer
      46th Controlled Release Society Annual Meeting & Exposition
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA therapeutics for ischemic neuronal death: Intraventricular administration of BDNF mRNA using polyplex nanomicelles2019

    • Author(s)
      Yuta Fukushima, Satoshi Uchida, Kazunori Kataoka, Keiji Itaka
    • Organizer
      19th Symposium for Gene Design and Delivery
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] メッセンジャーRNA医薬による軟骨・椎間板疾患治療2019

    • Author(s)
      位髙啓史
    • Organizer
      第20回運動器科学研究会
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] 新しい核酸医薬としてのmRNA医薬:その実用化に向けた課題2019

    • Author(s)
      位髙啓史
    • Organizer
      日本核酸医薬学会DDS部会主催合同サテライトシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] 新しい核酸医薬としてのmRNA医薬:その実用化に向けた課題2019

    • Author(s)
      位髙啓史
    • Organizer
      日本核酸医薬学会DDS部会主催合同サテライトシンポジウム2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA medicine for introducing therapeutic transcription factors2019

    • Author(s)
      Keiji Itaka
    • Organizer
      Keystone Symposia on Molecular and Cellular Biology: Protein Replacement through Nucleic Acid Therapies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA医薬の運動器疾患治療への応用2019

    • Author(s)
      位髙啓史
    • Organizer
      日本筋学会第5回学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03776
  • [Presentation] mRNA medicine as a new paradigm of gene therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      6th International mRNA Health Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      The 6th Japan-China Symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNAが生み出すパラダイムシフト~新たな核酸医薬品開発に向けて~2018

    • Author(s)
      位髙啓史
    • Organizer
      第24回創剤フォーラム若手研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA医薬を用いた脳神経疾患治療2018

    • Author(s)
      位髙啓史
    • Organizer
      第37回日本認知症学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Enhancement of motor function recovery in mice by delivery of mRNA nanomicelles encoding brain derived neurotrophic factor2018

    • Author(s)
      Samuel Crowley, Kazunori Kataoka, Keiji Itaka
    • Organizer
      3rd Japan-US Technical Information Exchange Forum on Blast Injury (JUFBI 2018)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA医薬の研究開発動向2018

    • Author(s)
      位髙啓史
    • Organizer
      日本核酸医薬学会第4回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      3rd International Symposium on Biomedical Engineering
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      3rd International Symposium on Biomedical Engineering
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapy for cartilage degeneration diseases2018

    • Author(s)
      Keiji Itaka, Shinsuke Ohba, Satoshi Uchida, Ung-il Chung, Kazunori Kataoka
    • Organizer
      5th TERMIS World Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA medicine as a new paradigm of gene therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      6th International mRNA Health Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA医薬を用いた脳神経疾患治療2018

    • Author(s)
      位髙啓史
    • Organizer
      第37回日本認知症学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNA医薬の研究開発動向2018

    • Author(s)
      位髙啓史
    • Organizer
      日本核酸医薬学会第4回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Treatment of spinal cord injury by injection of therapeutic mRNA-containing nanomicelles2018

    • Author(s)
      Samuel Crowley, 内田智士、片岡一則、位髙啓史
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] mRNAが生み出すパラダイムシフト~新たな核酸医薬品開発に向けて~2018

    • Author(s)
      位髙啓史
    • Organizer
      第24回創剤フォーラム若手研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA medicine as a new paradigm of gene therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      6th International mRNA Health Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2018

    • Author(s)
      Keiji Itaka
    • Organizer
      The 6th Japan-China Symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] Treatment of spinal cord injury by injection of therapeutic mRNA-containing nanomicelles2018

    • Author(s)
      Samuel Crowley, 内田智士、片岡一則、位髙啓史
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Enhancement of motor function recovery in mice by delivery of mRNA nanomicelles encoding brain derived neurotrophic factor2018

    • Author(s)
      Samuel Crowley, Kazunori Kataoka, Keiji Itaka
    • Organizer
      3rd Japan-US Technical Information Exchange Forum on Blast Injury
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA-based therapy for cerebral ischemia -Enhanced neuroprotective effects of astrocytes by BDNF mRNA2017

    • Author(s)
      Fukushima Y, Imai H, Uchida S, Nakatomi H, Kataoka K, Saito N, Itaka K
    • Organizer
      The 2nd Japan-US Technical Information Exchange Forum on Blast Injury JUFBI 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapeutics for intractable diseases and regenerative medicine2017

    • Author(s)
      K. Itaka
    • Organizer
      11th Annual Symposium on Nanobiotechnology 2017
    • Place of Presentation
      Kawasaki City Industrial Promotion Hall (Kanagawa, Japan)
    • Year and Date
      2017-02-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] mRNA投与による虚血性脳神経疾患に対する神経保護治療2017

    • Author(s)
      福島雄大, 内田智士,今井英明,中冨浩文, 片岡一則, 斉藤延人, 位高啓史
    • Organizer
      遺伝子・デリバリー研究会第17回シンポジウム
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017

    • Author(s)
      内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
    • Organizer
      第33回DDS学会学術大会
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] BDNF mRNA delivery using biocompatible nanomicellar carrier treats delayed neuronal death via enhanced neuroprotective effects of astrocytes2017

    • Author(s)
      Fukushima Y, Imai H, Uchida S, Nakatomi H, Kataoka K, Itaka K, Saito N
    • Organizer
      Neuroscience 2017
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2017

    • Author(s)
      Keiji Itaka
    • Organizer
      5th International mRNA Health Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17410
  • [Presentation] 中枢神経虚血性疾患に対するmRNA遺伝子治療:BDNF mRNAによる神経保護治療2017

    • Author(s)
      福島雄大, 内田智士,今井英明,中冨浩文, 片岡一則, 斉藤延人, 位高啓史
    • Organizer
      日本核酸医薬学会第3回年会
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017

    • Author(s)
      内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
    • Organizer
      日本核酸医薬学会第3回年会
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] Transient BDNF introduction therapy against delayed neuronal death in hippocampal CA1 neurons using biocompatible nanomicellar mRNA carrier2017

    • Author(s)
      Fukushima Y, Imai H, Uchida S, Nakatomi H, Kataoka K, Itaka K, Saito N
    • Organizer
      28th Symposium on Cerebral Blood Flow, Metabolism and Function
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] 虚血性脳神経疾患に対するmRNA投与による神経保護治療2017

    • Author(s)
      福島雄大, 内田智士,今井英明,中冨浩文, 片岡一則, 斉藤延人, 位高啓史
    • Organizer
      第33回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapy for intractable diseases and regenerative medicine2017

    • Author(s)
      Keiji Itaka
    • Organizer
      5th International mRNA Health Conference
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] mRNA-based therapeutics for intractable diseases and regenerative medicine.2017

    • Author(s)
      位高啓史
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] An Animal Study for Augmenting Clearance of Beta-Amyloid Using Neprilysin mRNA2016

    • Author(s)
      Keiji Itaka, Chin-Yu Lin, Satoshi Uchida, Kazunori Kataoka
    • Organizer
      4th International mRNA Conference
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2016-11-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Intracerebral administration of mRNA for treating brain diseases : An animal study for augmenting clearance of beta-amyloid using neprilysin mRNA2016

    • Author(s)
      K. Itaka, C. -Y. Lin, S. Uchida, K. Kataoka
    • Organizer
      The 4th International mRNA Conference
    • Place of Presentation
      Westin Boston Waterfront (Massachusetts, USA)
    • Year and Date
      2016-11-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 新しいバイオ医薬品としてのmRNA2016

    • Author(s)
      位髙啓史
    • Organizer
      東レ医薬研究ワークショップ
    • Place of Presentation
      東レ基礎研究センター医薬研究所(神奈川県鎌倉市)
    • Year and Date
      2016-01-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-14F04406
  • [Presentation] 運動感覚器機能を維持・再生するナノ再建術2016

    • Author(s)
      位高啓史, 片岡一則
    • Organizer
      第5回CSJ化学フェスタ2015
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2016-02-25
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] ナノDDSを用いたmRNAデリバリーとその応用2016

    • Author(s)
      位高啓史
    • Organizer
      第63回日本実験動物学会総会
    • Place of Presentation
      ミューザ川崎シンフォニーホール(神奈川県、川崎市)
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] ナノDDSを用いたmRNAデリバリーとその応用2016

    • Author(s)
      位髙啓史
    • Organizer
      第63回日本実験動物学会総会
    • Place of Presentation
      ミューザ川崎シンフォニーホール(神奈川県川崎市)
    • Year and Date
      2016-05-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] メッセンジャーRNA医薬を実現するDDS開発と疾患治療への応用2016

    • Author(s)
      位髙啓史
    • Organizer
      第32回日本DDS学会学術集会
    • Place of Presentation
      静岡県コンベンションアーツセンター(静岡県静岡市)
    • Year and Date
      2016-07-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] 新しいバイオ医薬品としてのメッセンジャーRNAの可能性2016

    • Author(s)
      位髙啓史
    • Organizer
      第15回国際バイオテクノロジー展(BIOTech2016)
    • Place of Presentation
      東京ビッグサイト(東京都江東区)
    • Year and Date
      2016-05-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polymeric nanocarrier2016

    • Author(s)
      Chin-Yu Lin、Satoshi Uchida、Masaru Ikegami、Keiji Itaka、Kazunori Kataoka
    • Organizer
      第16回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      川崎生命科学・環境研究センター(神奈川県川崎市)
    • Year and Date
      2016-05-16
    • Data Source
      KAKENHI-PROJECT-14F04406
  • [Presentation] mRNA-based therapeutics using nanoDDS for intractable diseases and serious injury2016

    • Author(s)
      Keiji Itaka
    • Organizer
      Japan-US Forum on Blast Injury 2016
    • Place of Presentation
      ニュー山王ホテル(東京都港区)
    • Year and Date
      2016-06-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA delivery using nano drug delivery systems for intractable diseases and regenerative medicine2016

    • Author(s)
      Keiji Itaka
    • Organizer
      Emerging Therapeutics Summit (ETS’16)
    • Place of Presentation
      Melbourne,Australia
    • Year and Date
      2016-11-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA医薬品の開発と治療応用に向けた戦略2016

    • Author(s)
      位髙啓史
    • Organizer
      日本薬物動態学会第31回会年会
    • Place of Presentation
      キッセイ文化ホール(長野県松本市)
    • Year and Date
      2016-10-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA delivery using nano drug delivery systems for intractable diseases and regenerative medicine2016

    • Author(s)
      Keiji Itaka
    • Organizer
      Ireland-Japan Biomaterials & Tissue Engineering Meeting
    • Place of Presentation
      Galway, Ireland
    • Year and Date
      2016-06-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] mRNA delivery using nano drug delivery systems for intractable diseases and regenerative medicine2016

    • Author(s)
      K. Itaka
    • Organizer
      Ireland-Japan Biomaterials & Tissue Engineering Meeting
    • Place of Presentation
      Meyrick Hotel (Galway, Ireland)
    • Year and Date
      2016-06-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] ナノミセルを用いたmRNA デリバリーによる遅発性細胞死に対する神経保護治療2016

    • Author(s)
      福島雄大、内田智士、今井英明、位髙啓史、片岡一則、斉藤延人
    • Organizer
      第16回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      川崎生命科学・環境研究センター(神奈川県川崎市)
    • Year and Date
      2016-05-16
    • Data Source
      KAKENHI-PROJECT-16K15642
  • [Presentation] Polyplex namomicelles assembled with neprilysin mRNA augmented clearance of beta-amyloid peptide from intracerebroventricular infusion2015

    • Author(s)
      C. -Y. Lin, S. Uchida, K. Itaka, K. Kataoka
    • Organizer
      2015 ESGCT and FSGT Collaborative Congress
    • Place of Presentation
      Finlandia Hall (Helsinki, Finland)
    • Year and Date
      2015-09-19
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 神経系をターゲットとしたmRNA送達と治療への応用2015

    • Author(s)
      位高啓史
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(兵庫県神戸市)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 神経系をターゲットとしたmRNA 送達と治療への応用2015

    • Author(s)
      位高啓史
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(神戸市)
    • Year and Date
      2015-03-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] メッセンジャーRNAデリバリーによる運動感覚機能再建2015

    • Author(s)
      位髙啓史,片岡一則
    • Organizer
      日本化学会,第5回CSJ化学フェスタ2015
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-10-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Messenger RNA-based therapy for an apoptosis-related disease in the liver2015

    • Author(s)
      S. Uchida, A. Matsui, K. Itaka, K. Kataoka
    • Organizer
      2015 ESGCT and FSGT Collaborative Congress
    • Place of Presentation
      Finlandia Hall (Helsinki, Finland)
    • Year and Date
      2015-09-18
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 転写因子mRNAの関節内投与による変形性関節症治療2015

    • Author(s)
      位髙啓史,Hailati Aini, 内田寛邦,内田智士,鄭雄一,大庭伸介,片岡一則
    • Organizer
      日本核酸医薬学会 第1回年会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] 新しいバイオ医薬品としてのmRNA2015

    • Author(s)
      位髙啓史
    • Organizer
      GE Life Sciences Day 2015
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川県横浜市)
    • Year and Date
      2015-07-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-14F04406
  • [Presentation] mRNAの核酸医薬としての応用2015

    • Author(s)
      位高啓史
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(神戸市)
    • Year and Date
      2015-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 末梢神経損傷における麻痺骨格筋へのアプローチ:IGF-1投与による筋萎縮防止・早期神経機能改善2015

    • Author(s)
      位髙 啓史,長田 和也,池上 賢,内田 智士,片岡 一則
    • Organizer
      第14回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 転写因子mRNAの関節内投与による変形性関節症治療2015

    • Author(s)
      位高啓史, H. Aini, 内田寛邦, 内田智士, 鄭雄一, 大庭伸介, 片岡一則
    • Organizer
      第1回日本核酸医薬学会大会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-12-01
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] メッセンジャーRNAを用いた新しい遺伝子治療と再生医療への応用2015

    • Author(s)
      位高啓史, 内田智士, 片岡一則
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-03
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] Treating neurological disorders by in vivo mRNA introduction using polyplex nanomicelles2015

    • Author(s)
      Keiji Itaka, Miyuki Baba, Hirokuni Uchida, Satoshi Uchida, Kazunori Kataoka
    • Organizer
      Biomaterials International 2015
    • Place of Presentation
      Kenting,Taiwan
    • Year and Date
      2015-06-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Treating neurological disorders by in vivo mRNA introduction using polyplex nanomicelles2015

    • Author(s)
      K. Itaka, M. Baba, H. Uchida, S. Uchida, K. Kataoka
    • Organizer
      Biomaterials International 2015
    • Place of Presentation
      Howard Beach Resort-Kenting (Kenting, Taiwan)
    • Year and Date
      2015-06-04
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 新しいバイオ医薬品としてのmRNA2015

    • Author(s)
      位髙啓史
    • Organizer
      GE Life Sciences Day 2015
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川県横浜市)
    • Year and Date
      2015-07-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] Messenger RNA (mRNA) -based gene therapy for introduction of an anti-apoptotic factor2015

    • Author(s)
      S. Uchida, A. Matsui, K. Itaka, K. Kataoka
    • Organizer
      ASGCT 18th Annual Meeting
    • Place of Presentation
      Hyatt Regency New Orleans (New Orleans, Louisiana, USA)
    • Year and Date
      2015-05-15
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] メッセンジャーRNAを用いた新しい遺伝子治療と再生医療への応用2015

    • Author(s)
      位髙啓史,内田智士,片岡一則
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] A disease-modifying strategy for osteoarthritis treatment by introducing mRNA encoding cartilage-anabolic transcription factor2015

    • Author(s)
      Keiji Itaka,Hailati Aini, Shinsuke Ohba, Ung-il Chung, Kazunori Kataoka.
    • Organizer
      3rd International mRNA Health Conference
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03017
  • [Presentation] A disease-modifying strategy for osteoarthritis treatment by introducing mRNA encoding cartilage-anabolic transcription factor2015

    • Author(s)
      K. Itaka
    • Organizer
      3rd International mRNA Health Conference
    • Place of Presentation
      Hilton Berlin, Berlin, Germany
    • Year and Date
      2015-11-12
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] N置換ポリアスバルタマイド側鎖の化学構造がmRNAポリプレックスの細胞内安定性及び発現持続性に及ぼす影響2015

    • Author(s)
      内田寛邦, 位高啓史, 宮田完二郎, 西山伸宏, 片岡一則
    • Organizer
      第1回日本核酸医薬学会大会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-12-01
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 高分子ナノミセルを用いた肝ターゲットmRNAデリバリー2014

    • Author(s)
      松井秋倫,内田智士,石井武彦,位髙啓史,片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー(東京都)
    • Year and Date
      2014-09-08
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Enhanced transfection of mRNA transcribed from elongated-poly(A/T) tail-containing vector.2014

    • Author(s)
      Masaru Ikegami, Satoshi Uchida, Hirokuni Uchida, Kazuya Nagata, Kazunori Kataoka and Keiji Itaka.
    • Organizer
      ASGCT 17th Annual Meeting
    • Place of Presentation
      Washington, DC, USA.
    • Year and Date
      2014-05-21
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 新しい治療用核酸としてのmRNA2014

    • Author(s)
      位髙啓史, 内田智士, 片岡一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学(東京都港区)
    • Year and Date
      2014-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] poly(A)鎖長の制御によるmRNAデリバリーの効率最大化2014

    • Author(s)
      池上 賢、内田 智士、内田 寛邦、長田 和也、片岡 一則、位高 啓史
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学薬学部芝共立キャンパス(東京都)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Treatment of neurological disorders by in vivo mRNA introduction using a novel carrier, polyplex nanomicelles2014

    • Author(s)
      Keiji Itaka, Miyuki Baba, Satoshi Uchida, Kazunori Kataoka
    • Organizer
      10th Annual Meeting of the Oligonucleotide Therapeutics Society.
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2014-10-12
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNAデリバリーにおける翻訳効率向上のためのpoly(A)鎖長の制御2014

    • Author(s)
      池上賢,内田智士,内田寛邦,長田和也,片岡一則,位髙啓史
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー(東京都)
    • Year and Date
      2014-09-08
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] In vivo mRNA introduction using polyplex nanomicelles to treat neurological disorders2014

    • Author(s)
      Keiji Itaka, Miyuki Baba, Satoshi Uchida, Kazunori Kataoka
    • Organizer
      ESGCT and NVGCT Collaborative Congress 2014
    • Place of Presentation
      The Hague, Netherlands
    • Year and Date
      2014-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 新しい治療用核酸としてのmRNA2014

    • Author(s)
      位高啓史
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学薬学部芝共立キャンパス(東京都)
    • Year and Date
      2014-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Reducing Amyloid-b in Mouse Brain by Intraventricular Injection of Neprilysin-expressing mRNA using Polyplex Nanomicelles2014

    • Author(s)
      Lin Chin-yu, 内田智士,池上賢,位髙啓史,片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー
    • Year and Date
      2014-09-08
    • Data Source
      KAKENHI-PROJECT-14F04406
  • [Presentation] 骨格筋へのIGF-1遺伝子導入による末梢神経損傷の早期機能回復2014

    • Author(s)
      長田和也,位髙啓史,片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー(東京都)
    • Year and Date
      2014-09-09
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNAの生体内送達:高分子ミセル型キャリアによる肝臓ターゲットデリバリー2014

    • Author(s)
      松井 秋倫,内田 智士,石井 武彦,位髙 啓史,片岡 一則
    • Organizer
      GE Life Sciences Day 2014
    • Place of Presentation
      パシフィコ横浜 会議センター(横浜市)
    • Year and Date
      2014-08-01
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNA投与による生体内での細胞アポトーシスシグナルの制御2014

    • Author(s)
      内田 智士,松井 秋倫,石井 武彦,位高 啓史,片岡 一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学薬学部芝共立キャンパス(東京都)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] DDSと3次元スフェロイド細胞移植システムの融合による脊髄損傷治療2014

    • Author(s)
      位髙 啓史,内田 智士,早川謙太郎,緒方 徹,片岡 一則
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      城山観光ホテル(鹿児島市)
    • Year and Date
      2014-10-10
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNA投与による生体内での細胞アポトーシスシグナル制御2014

    • Author(s)
      内田智士, 松井秋倫, 石井武彦, 位髙啓史, 片岡一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学(東京都港区)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] Reducing Amyloid-b in Mouse Brain by Intraventricular Injection of Neprilysin-expressing mRNA using Polyplex Nanomicelles.2014

    • Author(s)
      Lin Chin-yu, 内田智士,池上賢,位髙啓史,片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー(東京都)
    • Year and Date
      2014-09-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 肝臓への効率的なmRNA導入を目指したナノミセルキャリアの開発2014

    • Author(s)
      松井秋倫,内田智士,石井武彦,位髙啓史,片岡一則
    • Organizer
      第36回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2014-11-17
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] In vivo mRNA introduction using polyplex nanomicelles to treat neurological disorders2014

    • Author(s)
      K. Itaka
    • Organizer
      European Society Of Gene&Cell Therapy 2014(ESGCT)
    • Place of Presentation
      World Forum(Hague, Netherlands)
    • Year and Date
      2014-10-25
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] ポリアスパルタマイド側鎖のアミノエチレン構造の繰り返し数がmessenger RNA導入機構に及ぼす影響2014

    • Author(s)
      内田寛邦,位髙啓史,宮田完二郎,石井武彦,西山伸宏,片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学M&Dタワー(東京都)
    • Year and Date
      2014-09-09
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNAデリバリーの効率最大化:poly(A)鎖長を制御したmRNA調製法の確立2014

    • Author(s)
      池上賢,内田智士,内田寛邦,長田和也,片岡一則,位髙啓史
    • Organizer
      第36回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] マイクロパターン化基盤スフェロイド細胞培養と生体適合性遺伝子キャリアの融合による新規細胞移植システム2013

    • Author(s)
      位高啓史,内田智士,池上賢,柳原歌代子,遠藤泰輔,片岡一則
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] Treatment of sensory nerve disorder by in vivo mRNA introduction using polyplex nanomicelle2013

    • Author(s)
      K. Itaka, M. Baba, T. Ishii, K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (Honolulu, Hawaii, USA)
    • Year and Date
      2013-07-21
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 高分子ナノミセルを用いた中枢神経系への安全かつ持続的なmRNA導入2013

    • Author(s)
      内田智士、位髙啓史、内田寛邦、石井武彦、福島重人、長田健介、片岡一則
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京天学薬学部板橋キャンパス(東京都板橋区)
    • Year and Date
      2013-05-11
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 3次元スフェロイド培養と非ウイルス性遺伝子ベクターを組み合わせた新規細胞移植システムの開発2013

    • Author(s)
      内田智士,位高啓史,遠藤泰輔,柳原歌代子,野本貴大,松本有,石井武彦,片岡一則
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀
    • Year and Date
      2013-11-26
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] In vivo mRNA delivery using a novel non-viral carrier, polyplex nanomicelle2013

    • Author(s)
      K. Itaka, S. Uchida, K. Kataoka
    • Organizer
      FRONTIERS2013 - Joint EPFL/University of Tokyo Symposium on "Frontiers in Nanomedicine and Imaging"
    • Place of Presentation
      Swiss Federal Institute of Technology (Lausanne, Switzerland)
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] Regulation of mRNA immunogenicity by nanomicelle encapsulation for in vivo mRNA delivery2013

    • Author(s)
      S. Uchida, K. Itaka, H. Uchida, K. Hayakawa, T. Ogata, T. Ishii, S. Fukushima, K. Osada, K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (Honolulu, Hawaii, USA)
    • Year and Date
      2013-07-21
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] 3次元スフェロイド細胞培養とナノミセルによる遺伝子導入を融合した新規細胞移植システム2013

    • Author(s)
      内田智士,位高啓史,遠藤泰輔,野本貴大,松本有,片岡一則
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ
    • Year and Date
      2013-07-04
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] 3次元スフェロイド培養を用いた間葉系幹細胞移植による骨欠損治療2013

    • Author(s)
      柳原歌代子、内田智士、池上賢、前田祐二郎、大庭信介、位高啓史、片岡一則
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京大学板橋キャンパス
    • Year and Date
      2013-05-11
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] In vivo mRNA delivery system using polyplex nanomicelle and its application for neurologic disorders2013

    • Author(s)
      K. Itaka
    • Organizer
      International Symposium Optics for Health Sciences
    • Place of Presentation
      KAIST (Daejeon, Korea)
    • Year and Date
      2013-12-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] Treatment of neurological disorder by in vivo mRNA introduction using polyplex nanomicelle2013

    • Author(s)
      K. Itaka
    • Organizer
      7th Annual Symoposium on Nanobiotechnology
    • Place of Presentation
      Bristol Marriot Royal Hotel (Bristol, UK)
    • Year and Date
      2013-11-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Presentation] In vivo mRNA Introduction into CNS using non-viral polyplex nanomicelle2012

    • Author(s)
      Keiji Itaka
    • Organizer
      6th Annual Symposium on Nanobiotechnology ″Kyoto Cell-Material Integration 2012″
    • Place of Presentation
      京都大学 芝蘭会館(京都市)
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] In Vivo mRNA Delivery to Central Nervous System Using Polyplex Nanomicelles2012

    • Author(s)
      Uchida Satoshi, Keiji Itaka, et al.
    • Organizer
      American Society of Gene & Cell Therapy 15th Annual Meeting
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2012-05-18
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNA transfectionに最適化したカチオン性ポリマーの新規開発 : ポリアスパルタマイド側のアミノエチレン構造の繰り返し数がmRNA導入効率に及ぼす影響2012

    • Author(s)
      内田寛邦, 位高啓史, 他
    • Organizer
      日本バイオマテリアル学会シンポジウム2012
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2012-11-26
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Anovel platform of genetically-modified cell transplantation using 3D spheroid culture system on micropatterned substrates and polyplex nanomicelles2012

    • Author(s)
      Itaka K, Endo T, Uchida S, Kataoka K
    • Organizer
      American Society of Gene & Cell Therapy 15th Annual Meeting
    • Place of Presentation
      Philadelphia, PA, USA
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] In vivo mRNA introduction to central nervous system using polyplex nanomicelles2012

    • Author(s)
      Keiji Itaka
    • Organizer
      ESGCT and SFTCG Collaborative Congress 2012
    • Place of Presentation
      Versailles, France(招待講演)
    • Year and Date
      2012-10-28
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] ナノミセルによる実用的in vivo mRNAデリバリー2012

    • Author(s)
      位高啓史, 他
    • Organizer
      第12回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      仙台市民会館(仙台市)
    • Year and Date
      2012-09-04
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] ナノミセルを用いた中枢神経系へのin vivo mRNAデリバリー2012

    • Author(s)
      内田智士, 位高啓史, 他
    • Organizer
      第28回日本DDS学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2012-07-04
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Non-viral in vivo mRNA delivery using polypi ex nanomicelle2012

    • Author(s)
      Keiji Itaka, et al.
    • Organizer
      1st Joint Symposium 2012 Bridging Cancer Nanotechnology
    • Place of Presentation
      Houston, USA
    • Year and Date
      2012-08-13
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] マクロファージ活性化を回避する安全な肺への遺伝子導入2011

    • Author(s)
      位高啓史,内田智士, Qixian Chen,長田健介,石井武彦,柴田映子,柴田雅明,斯波真理子,片岡一則
    • Organizer
      第21回アンチセンスシンポジウム,第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
    • Place of Presentation
      大阪大学(大阪府吹田市)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible polyplex nanomicelle for safe and effective gene introduction minimizing inflammatory responses2011

    • Author(s)
      Itaka K
    • Organizer
      European Society of Gene and Cell Therapy, British Society for Gene Therapy, Collaborative Congress
    • Place of Presentation
      Brighton Center(Brighton, UK)
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible polyplex nanomicelle for safe and effective gene introduction minimizing inflammatory responses2011

    • Author(s)
      Keiji Itaka, Satoshi Uchida, Qixen Chen, Takehiko Ishii, Kensuke Osada, Kazunori Kataoka
    • Organizer
      European Society of Gene and Cell Therapy
    • Place of Presentation
      ブライトンセンター(英国)
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 機能性と炎症制御を両立させたナノキャリアによる肺への遺伝子導入2011

    • Author(s)
      位高啓史,内田智士, Qixian Chen,長田健介,石井武彦,柴田映子,柴田雅朗,斯波真理子,片岡一則
    • Organizer
      第33回日本バイオマテリアル学会大会
    • Place of Presentation
      京都府民総合交流プラザ京都テルサ(京都府京都市)
    • Year and Date
      2011-11-22
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biodegradable Polyamino Acid-Based Polycations for Safe and Effective Gene Transfer Minimizing Cumulative Toxicity2010

    • Author(s)
      Itaka K
    • Organizer
      13th Annual Meeting of American Society of Gene & Cell Therapy
    • Place of Presentation
      Marriot Wardman Park(Washington DC, USA)
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible Polyplex Nanomicelle for Safe and Effective Gene Transfer2010

    • Author(s)
      Itaka K
    • Organizer
      17th Annual Meeting of the German Society for Gene Therapy
    • Place of Presentation
      LMU Campus Groβhadern(Munich, Germany)
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biodegradable Polyamino Acid-Based Polycations for Safe and Effective Gene Transfer Minimizing Cumulative Toxicity2010

    • Author(s)
      Keiji Itaka
    • Organizer
      13th Annual Meeting of American Society of Gene, Cell Therapy
    • Place of Presentation
      Marriot Wardman Park (Washington DC, USA)
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Safe and effective gene delivery using biocompatible polyplex nanomicelle2010

    • Author(s)
      Itaka K
    • Organizer
      4th Annual Symposium on Nanobiotechnology
    • Place of Presentation
      Ludwig-Maximilians-Universitaet(Munich, Germany)
    • Year and Date
      2010-10-06
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生体適合性遺伝子キャリアとしてのナノミセル2010

    • Author(s)
      位高啓史
    • Organizer
      第26回日本DDS学会学術集会
    • Place of Presentation
      大阪国際交流センター(大阪府大阪市)
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生体適合性遺伝子キャリアとしてのナノミセル2010

    • Author(s)
      位高啓史
    • Organizer
      第26回日本DDS学会学術集会
    • Place of Presentation
      大阪国際交流センター(大阪市) 招待講演
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible Polyplex Nanomicelle for Safe and Effective Gene Transfe2010

    • Author(s)
      Keiji Itaka
    • Organizer
      Trilateral Symposium on NanoBio Integration
    • Place of Presentation
      Freie Universitat Berlin(Berlin, Germany) 招待講演
    • Year and Date
      2010-10-02
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Safe and effective gene delivery using biocompatible polyplex nanomicell2010

    • Author(s)
      Keiji Itaka
    • Organizer
      4th Annual Symposium on Nanobiotechnology
    • Place of Presentation
      Ludwig-Maximilians-Universitaet(Munich, Germany) 招待講演
    • Year and Date
      2010-10-06
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible Polyplex Nanomicelle for Safe and Effective Gene Transfer2010

    • Author(s)
      Itaka K
    • Organizer
      Trilateral Symposium on NanoBio Integration
    • Place of Presentation
      Freie Universitat Berlin(Berlin, Germany)
    • Year and Date
      2010-10-02
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible Polyplex Nanomicelle for Safe and Effective Gene Transfe2010

    • Author(s)
      Keiji Itaka
    • Organizer
      17th Annual Meeting of the German Society for Gene Therapy
    • Place of Presentation
      LMU Campus Groβhadern(Munich, Germany)
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生分解性ナノミセルによる遺伝子デリバリーと機能評価2009

    • Author(s)
      位高啓史, 石井武彦, 片岡一則
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京ドームホテル,東京
    • Year and Date
      2009-07-04
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 細胞をターゲットするドラッグ・遺伝子デリバリーシステムの研究展開2009

    • Author(s)
      位高啓史
    • Organizer
      第5回IN Cell User's Day(招待講演)
    • Place of Presentation
      蚕糸科学研究所,東京
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Gene delivery with structure-specific biodegradable polymer-safe and sustained transgene expression by avoiding cumulative toxicity2009

    • Author(s)
      Itaka K
    • Organizer
      10th US-Japan Symposium on Drug Delivery Systems
    • Place of Presentation
      Maui Resort & Spa, Lahaina(Hawaii, USA)
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Engineered Supra-Macromolecular Assemblies as Nanodevices for Gene and Nucleic Acid Delivery.2009

    • Author(s)
      位高啓史
    • Organizer
      2nd Asian Biomaterials Congress(ABMC)(招待講演)
    • Place of Presentation
      National University of Singapore, Singapore
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Engineered Supra-Macromolecular Assemblies as Nanodevices for Gene and Nucleic Acid Delivery2009

    • Author(s)
      Itaka K
    • Organizer
      2nd Asian Biomaterials Congress(ABMC)
    • Place of Presentation
      National University of Singapore(Singapore)
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生分解性カチオニックポリマーによる遺伝子デリバリー2009

    • Author(s)
      位高啓史,石井武彦,片岡一則
    • Organizer
      遺伝子・デリバリー研究会第9回シンポジウム
    • Place of Presentation
      大阪大学コンベンションセンター(大阪府吹田市)
    • Year and Date
      2009-07-11
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生分解性ナノミセルによる遺伝子デリバリーと機能評価2009

    • Author(s)
      位高啓史,石井武彦,片岡一則
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京ドームホテル(東京都)
    • Year and Date
      2009-07-04
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 細胞をターゲットするドラッグ・遺伝子デリバリーシステムの研究展開2009

    • Author(s)
      位高啓史
    • Organizer
      第5回IN Cell User's Day
    • Place of Presentation
      蚕糸科学研究所(東京都)
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Gene delivery with structure-specific biodegradable polymer-safe and sustained transgene expression by avoiding cumulative toxicity2009

    • Author(s)
      位高啓史
    • Organizer
      10th US-Japan Symposium on Drug Delivery Systems
    • Place of Presentation
      Maui Resort & Spa, Lahaina, Maui, Hawaii, USA
    • Year and Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Block copolymer micelles as smart nanocarriers for tumor targeting.2009

    • Author(s)
      位高啓史
    • Organizer
      International conference on materials for advanced technologies 2009(ICMAT)and International union of material research societies-International conference in Asia(IUMRA-ICA 2009)(招待講演)
    • Place of Presentation
      Suntec Singapore International Convention & Exhibition Centre, Singapore
    • Year and Date
      2009-06-29
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] 生分解性カチオニックポリマーによる遺伝子デリバリー2009

    • Author(s)
      位高啓史, 石井武彦, 片岡一則
    • Organizer
      遺伝子・デリバリー研究会第9回シンポジウム
    • Place of Presentation
      大阪大学コンベンションセンター,大阪
    • Year and Date
      2009-07-11
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Block copolymer micelles as smart nanocarriers for tumor targeting2009

    • Author(s)
      Itaka K
    • Organizer
      International conference on materials for advanced technologies 2009(ICMAT) and International union of material research societies-International conference in Asia(IUMRA-ICA 2009)
    • Place of Presentation
      Suntec Singapore International Convention & Exhibition Centre(Singapore)
    • Year and Date
      2009-06-29
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible nanocarrier for gene and siRNA delivery2009

    • Author(s)
      Itaka K
    • Organizer
      First World Congress of International Academy of Nanomedicine(IANM)
    • Place of Presentation
      Sanya(Hainan, China)
    • Year and Date
      2009-06-13
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Biocompatible nanocarrier for gene and siRNA delivery.2009

    • Author(s)
      位高啓史
    • Organizer
      First World Congress of International Academy of Nanomedicine(IANM)(招待講演)
    • Place of Presentation
      Sanya, Hainan, China
    • Year and Date
      2009-06-13
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Presentation] Supra-molecular Assembly of Block Copolymers as Smart Nanocarriers for Gene and Drug Delivery2008

    • Author(s)
      Keiji Itaka
    • Organizer
      Materials Research Society (MRS) 2008 Spring Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2008-03-25
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Supra-molecular Assembly of Block Copolymers as Smart Nanocarriers for Gene and Drug Delivery2008

    • Author(s)
      Itaka K, et. al.
    • Organizer
      Materials Research Society (MRS) 2008 Spring Meeting
    • Place of Presentation
      San Francisco, CA, U.S.A.
    • Year and Date
      2008-03-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Pharmacogenomic analysis of non-viral gene transfer:Feasibility of effective cell differentitation toward tissue engineering.2007

    • Author(s)
      Itaka K, et. al.
    • Organizer
      10th Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      Seattle, WA. U.S.A.
    • Year and Date
      2007-06-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] In vivo bone regeneration without cell transplantation using supramolecular nanocarrier for gene delivery2007

    • Author(s)
      Keiji Itaka
    • Organizer
      第13回日本遺伝子治療学会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] ナノミセル型遺伝子キャリアの再生医療への応用と機能解析2007

    • Author(s)
      位高 啓史
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-26
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] ナノミセル遺伝子デリバリーの再生医療への応用2007

    • Author(s)
      位高 啓史
    • Organizer
      第29回日本バイオマテリアル学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-26
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Pharmacogenomic analysis of non-viral gene transfer: Feasibility of effective cell differentiation toward tissue engineering2007

    • Author(s)
      Keiji Itaka
    • Organizer
      10th Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      Seattle, WA.U.S.A
    • Year and Date
      2007-05-31
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Pharmacogenomic analysis of non-viral gene transfer : Feasibility of effective cell differentiation toward tissue engineering2007

    • Author(s)
      Itaka K
    • Organizer
      10th Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      Seattle, WA. U.S.A.
    • Year and Date
      2007-06-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Bone Regeneration by Osteogenic Gene Delivery without Cell Transplantation Using Supramolecular Nanocarrier2006

    • Author(s)
      Itaka K, et. al.
    • Organizer
      9th Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      Baltimore, MD. U.S.A.
    • Year and Date
      2006-06-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Biocompatible nanocarrier of plasmid DNA for bone regeneration2006

    • Author(s)
      Itaka K, et. al.
    • Organizer
      33rd Annual Meeting et Exposition of the Controlled Release Society
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2006-07-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Supramolecular nanocarrier for DNA facilitating regulated gene expression2005

    • Author(s)
      Itaka K, et. al.
    • Organizer
      The 6th International Conference on Intelligent Materials and Systems ICIM'05
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2005-07-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] Supramolecular nanocarrier for DNA facilitating regulated gene expression2005

    • Author(s)
      Itaka K
    • Organizer
      The 6th International Conference on Intelligent Materials and Systems ICIM''05
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2005-07-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Presentation] mRNA生体内デリバリーによる嗅覚神経障害の機能回復

    • Author(s)
      位高 啓史,馬場 美雪,石井 武彦,近藤 健二,山岨 達也,片岡 一則
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都市)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNA 肝ターゲットデリバリーへの高分子ナノミセルの応用

    • Author(s)
      松井 秋倫,内田 智士,石井 武彦,位高 啓史,片岡 一則
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 生体適合性ナノDDSによる核酸デリバリーと疾患治療への応用

    • Author(s)
      位高啓史
    • Organizer
      第14回運動器科学研究会
    • Place of Presentation
      汐留コンファレンスセンター(東京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] IGF-1発現pDNAの生体適合性キャリアを用いた骨格筋デリバリーによる末梢神経外傷後の早期機能回復

    • Author(s)
      長田和也、位高啓史、石井武彦、片岡一則
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都市)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] In vivo mRNA delivery system using polyplex nanomicelle and its application for neurologic disorders

    • Author(s)
      K.Itaka
    • Organizer
      International symposium on optics for health science
    • Place of Presentation
      Daejeon, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] IGF-1 Gene Delivery by Polyplex Nanomicelle Promotes Neural Function Recovery after Adult PNS Injury on Diabetic Mice

    • Author(s)
      Kazuya Nagata, Keiji Itaka, Takehiko Ishii, and Kazunori Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 3次元スフェロイド培養を用いた間葉系幹細胞移植による骨欠損治療

    • Author(s)
      柳原歌代子、内田智士、池上賢、前田祐二郎、大庭信介、位高啓史、片岡一則
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京大学板橋キャンパス(東京都)
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] Non-viral gene introduction using polyplex nanomicelles for regenerative medicine

    • Author(s)
      Keiji Itaka
    • Organizer
      Dutch - Japanese Cross Debate Workshop on RM and Stem cells
    • Place of Presentation
      Yokohama
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] 3次元スフェロイド細胞培養とナノミセルによる遺伝子導入を融合した新規細胞移植システム

    • Author(s)
      内田智士,位高啓史,遠藤泰輔,野本貴大,松本有,片岡一則
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都市)
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] 神経障害の機能再生に向けた新規アプローチ:mRNAの生体内デリバリー

    • Author(s)
      位高 啓史,馬場 美雪,内田 智士,石井 武彦,近藤 健二,山岨 達也,片岡 一則
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 骨格筋ターゲット遺伝子導入による末梢神経外傷モデルの早期機能回復

    • Author(s)
      長田 和也、位高 啓史、石井 武彦、片岡 一則.
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京大学板橋キャンパス(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Treatment of neurological disorder by in vivo mRNA introduction using polyplex nanomicelle

    • Author(s)
      Itaka K.
    • Organizer
      7th Annual Symposium on Nanobiotechnology 2013
    • Place of Presentation
      Bristol, UK
    • Invited
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 脊髄組織でタンパク持続発現を可能とするmRNAデリバリーシステムの開発と脊髄損傷治療への展開

    • Author(s)
      位高啓史,内田智士,早川謙太郎,緒方徹,片岡 一則
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      幕張メッセ国際会議場(千葉市)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 高分子ナノミセルを用いた中枢神経系への安全かつ持続的なmRNA導入

    • Author(s)
      内田 智士、位高 啓史、内田 寛邦、石井 武彦,福島 重人、長田 健介、片岡 一則
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京大学板橋キャンパス(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] mRNAポリプレックスの安定性とその発現持続性に及ぼすポリアスパルタミド側鎖構造の効果

    • Author(s)
      内田 寛邦,位高 啓史,宮田 完二郎,石井 武彦, 西山 伸宏,片岡 一則
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 生体適合性遺伝子ナノキャリアの開発研究と疾患治療への応用

    • Author(s)
      位高 啓史
    • Organizer
      第33回日本バイオマテリアル学会大会(招待講演)
    • Place of Presentation
      京都府民総合交流プラザ京都テルサ(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] Treatment of sensory nerve disorder by in vivo mRNA introduction using polyplex nanomicelle

    • Author(s)
      K. Itaka, M. Baba, T. Ishii, and K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] 3次元スフェロイド培養と非ウイルス性遺伝子ベクターを組み合わせた新規細胞移植システムの開発

    • Author(s)
      内田 智士,位高 啓史,遠藤 泰輔,柳原 歌代子,野本 貴大,松本 有,石井 武彦,片岡一則
    • Organizer
      第35回日本バイオマテリアル学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Data Source
      KAKENHI-PROJECT-23659708
  • [Presentation] In vivo mRNAデリバリーによる嗅覚神経障害モデルの機能回復

    • Author(s)
      位高 啓史,馬場 美雪,石井 武彦,近藤 健二,山岨 達也,片岡 一則
    • Organizer
      第13回遺伝子・デリバリー研究会シンポジウム
    • Place of Presentation
      帝京大学板橋キャンパス(東京都)
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] In vivo mRNA delivery using polyplex nanomicelle with reduced immunological responses

    • Author(s)
      S. Uchida, K. Itaka, H. Uchida, K. Hayakawa, T. Ogata, T. Ishii, S. Fukushima, K. Osada, K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-24300170
  • [Presentation] Polyplex nanomicelles for safe and effective gene delivery

    • Author(s)
      Keiji Itaka
    • Organizer
      Seoul NanoHealth 2011, 5th Annual Symposium on Nanobiotechnology(招待講演)
    • Place of Presentation
      Yonsei大学(韓国)
    • Data Source
      KAKENHI-PROJECT-23659708
  • 1.  TEI Yuichi (30345053)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 2.  KATAOKA Kazunori (00130245)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 55 results
  • 3.  KAWAGUCHI Hiroshi (40282660)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  NISHIYAMA Nobuhiro (10372385)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 5.  ISHII Takehiko (80415075)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 21 results
  • 6.  OSADA Kensuke (10396947)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 7.  OGATA Toru (00392192)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 8.  NAKAMURA Kozo (60126133)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  MIYATA Kanjiro (50436523)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  Imai Hideaki (70359587)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 11.  Onoue Kenji (90510173)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  Hirai Takashi (40510350)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 13.  大庭 伸介 (20466733)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  酒井 崇匡 (70456151)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  吉井 俊貴 (50583754)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 16.  福島 雄大 (40837895)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  LIN CHIN-YU
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 18.  YAMASAKI Yuichi (00322678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAGA Nobuhiko (80251263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YOKOTA Takanori (90231688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TSUMOTO Kouhei (90271866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  ANRAKU Yasutaka (60581585)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MATSUMOTO Yu (80548553)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 24.  UCHIDA Satoshi (20710726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 29 results
  • 25.  HOSHI Kazuto (30344451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  OGASAWARA Toru (20359623)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  MATSUBARA Takehiro (40361498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  IKEDA Toshiyuki (80322759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  Tokura Yoshiki (00172156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  Hirakawa Satoshi (50419511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  Yoshimoto Takayuki (80202406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  Matsumto Masahito (90321819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  Ohtsuki Takashi (80321735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  小牧 裕司 (10548499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  筑田 博隆 (30345219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  北條 宏徳 (80788422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  石崎 泰樹 (90183003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  宮脇 哲 (70407914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  小野 秀明 (50771846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  齊藤 延人 (60262002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  岡崎 康司 (80280733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  大川 淳 (30251507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  松崎 典弥 (00419467)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 44.  立花 克郎 (40271605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  貴田 浩志 (80529454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  安田 充 (20742307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  Wakimoto Hiroko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  CROWLEY SAMUEL
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 49.  SAITO Taku
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  NOZAKI Kosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  山崎 裕太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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