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Takeda Atsushi  武田 篤

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TAKEDA Atsushi  武田 篤

TAKEDA Atushi  武田 篤

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Researcher Number 70261534
Other IDs
Affiliation (Current) 2025: 独立行政法人国立病院機構仙台西多賀病院(臨床研究部), 独立行政法人国立病院機構仙台西多賀病院, 院長
Affiliation (based on the past Project Information) *help 2017: 独立行政法人国立病院機構, 仙台西多賀病院, 院長
2014 – 2015: 独立行政法人国立病院機構仙台西多賀病院(臨床研究部), その他部局等, その他
2014: 独立行政法人国立病院機構, 仙台西多賀病院, 院長
2013: 東北大学, 医学(系)研究科(研究院), 大学院非常勤講師
2013: 東北大学, 医学(系)研究科(研究院), 非常勤講師 … More
2013: 東北大学, 大学院医学系研究科, 准教授
2012: 東北大学, 大学院・医学系研究科, 准教授
2011 – 2012: 東北大学, 医学(系)研究科(研究院), 准教授
2007 – 2009: Tohoku University, 大学院・医学系研究科, 准教授
2005: Tohoku University, Hospital, Lecturer, 病院, 講師
2002 – 2004: Tohoku University, Neurology, Research Associate, 大学院・医学系研究科, 助手
2001: 東北大学, 大学院・医学研究科, 助手
2000: 東北大学, 大学院・医学系研究科, 助手
1998: 東北大学, 医学部, 助手
1997: 東北大学, 医学部・附属病院, 助手
1995 – 1996: 東北大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Neurology / Neurology / Biological Sciences / Biological Sciences
Except Principal Investigator
Neurology / Neurology / Ophthalmology
Keywords
Principal Investigator
パーキンソン病 / 多系統萎縮症 / シヌクレイノパチー / Parkinson disease / bilirubin / heme oxygenase / 神経細胞死 / 神経変性 / Alzheimer disease / neurodegeneration … More / oxidative stress / alpha-synuclein / 分子イメージング / グリア細胞質封入体 / レビー小体 / αシヌクレイン / ヘムオキシゲナーゼ / 酸化的ストレス / CO / biliverdin / antioxidant / synucleinopathy / Multiple system atrophy / dopamine oxidation / quinone / neuronal death / カテコラミン / 細胞モデル / ドーパミン酸化物 / キノン体 / multiple system atrophy / nucleic acid oxidation / RNA oxidation / oxidative stresses / ミオパチー / rimmed-vacuole / biopyrrin / アルツハイマー病 / 核酸酸化 / RNA酸化 / 髄液 / エクソソーム / miRNA / バイオマーカー / シヌクレイン / BF-227 / レビー小体型認知症 / ミトコンドリア / 小胞体ストレス / アポトーシス / αシヌクレン / シヌクレノパチー / ビリルビン / アツルハイマー病 / CSF / biopyrrins / bilirerdin / bilirabin / oxidafive stress / Heme oxygenase / oxidutive stress / neuro degeneration / heme … More
Except Principal Investigator
ischemia / α-シヌクレイン / パーキンソン病 / neuronal death / inflammation / neurotrophic factor / antioxidant / oxidative stress / cytokine / [11C]BF-227 / PET / 多系統萎縮症 / 小胞輸送 / [11C] BF-227 / oxdiative stress / in flammation / liposomes / excitotoxicity / glutamate / growth factors / neurotrophic factors / cytokines / retinal damage / 興奮毒 / グルタミン酸 / 細胞増殖因子 / 神経栄養因子 / リポソーム / 生理活性物質 / 虚血性眼底疾患 / 虚血 / Nedd4 / ESCRT / alpha-synuclein / 細胞間伝播 / オリゴデンドログリア / 神経細胞 / エンドサイトーシス / セルトラリン / エンドソーム / ダイナミン / エキソソーム / プリオン仮説 / αシヌクレイン / 異常凝集タンパク Less
  • Research Projects

    (16 results)
  • Research Products

    (214 results)
  • Co-Researchers

    (20 People)
  •  In vivo visualization of synuclein deposits in Parkinson's disease and its clinical applicability

    • Principal Investigator
      Kikuchi Akio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  内在化αシヌクレインにおけるESCRTを中心とした小胞輸送に関する研究

    • Principal Investigator
      菅野 直人
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  シヌクレイノパチーの分子イメージングPrincipal Investigator

    • Principal Investigator
      武田 篤
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Early diagnosis and treatment of Parkinson disease dementiaPrincipal Investigator

    • Principal Investigator
      TAKEDA ATSUSHI
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Sendai Nishitaga National Hospital
      Tohoku University
  •  micro RNA as a novel biomarker for neurodegenerative disesesPrincipal Investigator

    • Principal Investigator
      TAKEDA Atsushi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Analysis of molecular mechanisms behind the prion hypothesis in synucleinopathy

    • Principal Investigator
      HASEGAWA Takafumi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  In vivo visualization of synuclein deposition in multiple system atrophy and its clinical applicability

    • Principal Investigator
      KIKUCHI Akio
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Molecular mechanisms of cell death in synucleinopathyPrincipal Investigator

    • Principal Investigator
      TAKEDA Atsushi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Aggregation of alpha-synuclein and mechanisms of cell deathPrincipal Investigator

    • Principal Investigator
      TAKEDA Atsushi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      TOHOKU UNIVERSITY
  •  α-Synuclein代謝異常と酸化的ストレス-特にヘム異化系との関連Principal Investigator

    • Principal Investigator
      武田 篤
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Roles of oxidative stresses in neurodegeneration and myodegeneration focusing on the heme catabolismPrincipal Investigator

    • Principal Investigator
      TAKEDA Atsushi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  中枢神経系に於けるヘム異化の意義:特に神経変性機構との関連についてPrincipal Investigator

    • Principal Investigator
      武田 篤
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  中枢神経系に於けるヘム異化の意義:特に神経変性機構との関連についてPrincipal Investigator

    • Principal Investigator
      武田 篤
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  中枢神経系に於けるヘム異化の意義:特に神経変性機構との関連についてPrincipal Investigator

    • Principal Investigator
      武田 篤
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Treatment of ischemic retinal injury by administration of various cytokines through vitreous cavity.

    • Principal Investigator
      TAMAI Makoto
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Mechanism of Ischemic Neuronal Death : Neuron, Glial interaction

    • Principal Investigator
      NAKAMURA Shozo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] パーキンソン病実践診療マニュアル2016

    • Author(s)
      武田篤(編著)
    • Total Pages
      280
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Book] Visual function in Parkinson’s disease. in Chaudhuri KR., Tolosa E, Schapira AHV., & Poewe W. (ed.); Non-motor symptoms of Parkinson’s disease 2nded.2014

    • Author(s)
      Baba T., Estrada-Bellmann I., Mori E., Takeda A.
    • Total Pages
      11
    • Publisher
      Oxford University Press
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Book] パーキンソン病、「ガイドライン外来診療2013」(泉孝英編)2013

    • Author(s)
      武田篤
    • Publisher
      日経メディカル開発
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Book] (第5章)パーキンソン病とその他の症状や疾患その考え方と対応パーキンソン病と嗅覚障害の関係は?【あなたも名医!ここを押さえる!パーキンソン病診療34のギモンに答える】jmed mook23号2012

    • Author(s)
      馬場徹、武田篤
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Book] 痙性斜頚のPET、「ジストニア2012」(長谷川一子編)2012

    • Author(s)
      武田篤、菊池昭夫
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Book] パーキンソン病の病因・病態生理、「GP・レジデントのためのパーキンソン病テキストブック」(山本光利編)2012

    • Author(s)
      武田篤
    • Publisher
      アルタ出版
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Journal Article] Parkinson’s disease-linked DNAJC13 mutation aggravates α-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.2018

    • Author(s)
      Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y and Aoki M.
    • Journal Title

      Hum Mol Genet.

      Volume: 27 Issue: 5 Pages: 823-836

    • DOI

      10.1093/hmg/ddy003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09744, KAKENHI-PROJECT-17K09745, KAKENHI-PROJECT-17K19658, KAKENHI-PROJECT-17K16134, KAKENHI-PROJECT-16H05325, KAKENHI-PUBLICLY-17H05682, KAKENHI-PUBLICLY-17H05683, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-15K19502, KAKENHI-PROJECT-17K09789, KAKENHI-PROJECT-15K09331
  • [Journal Article] Longitudinal study of cognitive and cerebral metabolic changes in Parkinson's disease.2017

    • Author(s)
      Baba T, Hosokai Y, Nishio Y, Kikuchi A, Hirayama K, Suzuki K, Hasegawa T, Aoki M, Takeda A, Mori E.
    • Journal Title

      J Neurol Sci

      Volume: 372 Pages: 288-293

    • DOI

      10.1016/j.jns.2016.11.068

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01550, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-17K09789
  • [Journal Article] Subgroup differences in “brain-type” transferrin and alpha-synuclein in Parkinson's disease and multiple system atrophy2016

    • Author(s)
      A Yoshihara, M Fukatsu, K Hoshi, Y Hashimoto, et. al
    • Journal Title

      The Journal of Biochemistry

      Volume: 159 Issue: 2 Pages: 87-91

    • DOI

      10.1093/jb/mvw015

    • Description
      未定
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H00638, KAKENHI-PROJECT-24390219, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-15K09322, KAKENHI-PROJECT-26461303, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-26460394, KAKENHI-PROJECT-16H04758
  • [Journal Article] On the utility of MIBG SPECT/CT in evaluating cardiac sympathetic dysfunction in Lewy body diseases2016

    • Author(s)
      Odagiri H, Baba T, Nishio Y, Iizuka O, Matsuda M, Inoue K, Kikuchi A, Hasegawa T, Aoki M, Takeda A, Taki Y, Mori E
    • Journal Title

      PLoS One

      Volume: 11(4) Issue: 4 Pages: 0152746-0152746

    • DOI

      10.1371/journal.pone.0152746

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PUBLICLY-15H01550, KAKENHI-PROJECT-26461303
  • [Journal Article] In vivo visualization of tau pathology using 18F-THK5351 PET in corticobasal syndrome.2016

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Kobayashi M, Tano O, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Ezura M, Hiraoka K, Mugikura S, Takase K, Iwata R, Taki Y, Furukawa K, HArai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A,Aoki M.
    • Journal Title

      Neurology

      Volume: 87 Issue: 22 Pages: 2309-2316

    • DOI

      10.1212/wnl.0000000000003375

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01550, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-15H04900, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-15K19767, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-16K15570
  • [Journal Article] Brain Metabolic Changes of Cervical Dystonia with Spinocerebellar Ataxia Type 1 after Botulinum Toxin Therapy2016

    • Author(s)
      Kikuchi A, Takeda A, Sugeno N, Miura E, Kato K, Hasegawa T, Baba T, Konno M, Oshima R, Watanuki S, Hiraoka K, Tashiro M, Aoki M
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 14 Pages: 1919-1922

    • DOI

      10.2169/internalmedicine.55.5843

    • NAID

      130005164997

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-26461303
  • [Journal Article] ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways2016

    • Author(s)
      Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M and Tanaka N
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 24997-24997

    • DOI

      10.1038/srep24997

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461263, KAKENHI-PUBLICLY-15H01550, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-26461303
  • [Journal Article] Loss of awareness of hyposmia is associated with mild cognitive impairment in Parkinson's disease.2016

    • Author(s)
      Kawasaki I., Baba T., Takeda A., Mori E.
    • Journal Title

      Parkinsonism & related dis.

      Volume: 22 Pages: 74-79

    • DOI

      10.1016/j.parkreldis.2015.11.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-26860657
  • [Journal Article] Pareidolia in Parkinson's disease without dementia: A positron emission tomography study.2015

    • Author(s)
      Uchiyama M., Nishio Y., Yokoi K., Hosokai Y., Takeda A., Mori E.
    • Journal Title

      Parkinsonism & relat. disord

      Volume: 21 Issue: 6 Pages: 603-609

    • DOI

      10.1016/j.parkreldis.2015.03.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Journal Article] K63-linked ubiquitination by E3 Ubiquitin Ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein.2014

    • Author(s)
      Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 26 Pages: 18137-18151

    • DOI

      10.1074/jbc.m113.529461

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303
  • [Journal Article] VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease.2014

    • Author(s)
      Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M.
    • Journal Title

      Neurobio Dis

      Volume: 71 Pages: 1-13

    • DOI

      10.1016/j.nbd.2014.07.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24591286, KAKENHI-PUBLICLY-25110741, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-26670446
  • [Journal Article] Olfactory Dysfunction and Dementia in Parkinson's Disease.2014

    • Author(s)
      Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E.
    • Journal Title

      J Parkinsons Dis

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] Improvement of freezing of gait in patients with Parkinson’s disease by imagining bicycling.2014

    • Author(s)
      Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Oshima R, Aoki M, Takeda A.
    • Journal Title

      Case Rep Neurol

      Volume: 6 Issue: 1 Pages: 92-95

    • DOI

      10.1159/000362119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-25461264, KAKENHI-PROJECT-26461303
  • [Journal Article] Isolated posterior column lesion in a case with mixed connective tissue disease2014

    • Author(s)
      Tomomi Shijo, Naoto Sugeno, Hiroshi Kuroda, Takafumi Hasegawa, Atsushi Takeda and Masashi Aoki
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: in press Issue: 3 Pages: 95-95

    • DOI

      10.1111/ncn3.88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Journal Article] 1.Neural Substrates of Cognitive Subtypes in Parkinson's Disease: A 3-Year Longitudinal Study2014

    • Author(s)
      Shoji Y¸ Nishio Y, Baba T, Uchiyama M, Yokoi K, Ishioka T, Hosokai Y, Hirayama K, Fukuda H, Aoki M, Hasegawa T, Takeda A, Mori E.
    • Journal Title

      PLoS ONE

      Volume: 9(10) Issue: 10 Pages: e110547-e110547

    • DOI

      10.1371/journal.pone.0110547

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23700617, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-26461263
  • [Journal Article] Cognitive impairment in multiple system atrophy : A position statement by the Neuropsychology Task Force of the MDS multiple system atrophy (MODIMSA) Study Group2014

    • Author(s)
      Stankovic I., Krismer F., Jesic A., Antonini A., Benke T., Brown RG., Burn DJ., Holton JL., Kaufmann H., Kostic VS., Ling H., Meissner WG., Poewe W., Semnic M., Seppi K., Takeda A., Weintraub D., Wenning GK.
    • Journal Title

      Movement Disorders

      Volume: (in press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/24753321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Journal Article] K63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein2014

    • Author(s)
      Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
    • Journal Title

      Journal of Biological Chemistry

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Journal Article] Olfactory Dysfunction and Dementia in Parkinson's Disease.2014

    • Author(s)
      Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E.
    • Journal Title

      J Parkinsons Dis.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Journal Article] Cognitive impairment in multiple system atrophy: A position statement by the Neuropsychology Task Force of the MDS multiple system atrophy (MODIMSA) Study Group.2014

    • Author(s)
      Stankovic I., Krismer F., Jesic A., Antonini A., Benke T., Brown RG., Burn DJ., Holton JL., Kaufmann H., Kostic VS., Ling H., Meissner WG., Poewe W., Semnic M., Seppi K., Takeda A., Weintraub D., Wenning GK.
    • Journal Title

      Movement Disorders

      Volume: 29 Issue: 7 Pages: 857-867

    • DOI

      10.1002/mds.25880

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Journal Article] Olfactory dysfunction and dementia in Parkinson's disease.2014

    • Author(s)
      Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E.
    • Journal Title

      J Parkinsons Dis

      Volume: 4 Issue: 2 Pages: 181-187

    • DOI

      10.3233/jpd-130277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-26461263, KAKENHI-PROJECT-26461303
  • [Journal Article] Olfactory dysfunction and dementia in Parkinson's disease2014

    • Author(s)
      Takeda A., Baba T., Kikuchi A., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E.
    • Journal Title

      J. Parkinsons Dis

      Volume: (in press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/24625830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Journal Article] Pathogenesis of Multiple system atrophy.2013

    • Author(s)
      Hasegawa T, Kikuchi A, Takeda A.
    • Journal Title

      Neurol Clin Neurosci

      Volume: 1 (6) Issue: 6 Pages: 189-194

    • DOI

      10.1111/ncn3.57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228, KAKENHI-PUBLICLY-24111502, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24659423
  • [Journal Article] Choreoathetosis in a patient with neuromyelitis optica spectrum disorder2013

    • Author(s)
      Naoto Sugeno, Rumiko Izumi, Kazuhiro Kato, Ichiro Nakashima, Atsushi Takeda and Masashi Aoki
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 1 Issue: 4 Pages: 154-156

    • DOI

      10.1111/ncn3.36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Journal Article] Pathogenesis of multiple system atrophy.2013

    • Author(s)
      Hasegawa T, Kikuchi A, Takeda A.
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 1 Issue: 4 Pages: 189-194

    • DOI

      10.1007/s00415-014-7271-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-26461303
  • [Journal Article] Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study2013

    • Author(s)
      Akio Kikuchi, Toru Baba, Takafumi Hasegawa, Michiko Kobayashi, Naoto Sugeno, Masatoshi Konno, Emiko Miura, Yoshiyuki Hosokai, Toshiyuki Ishioka, Yoshiyuki Nishio, Kazumi Hirayama, Kyoko Suzuki, Masashi Aoki, ShokiTakahashi, Hiroshi Fukuda, Yasuto Itoyama, Etsuro Mori, Atsushi Takeda
    • Journal Title

      BMJ Open

      Volume: 3 Issue: 3 Pages: e002249-e002249

    • DOI

      10.1136/bmjopen-2012-002249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PUBLICLY-24111502, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-24659423, KAKENHI-PROJECT-25461264
  • [Journal Article] Anti-voltage-gated potassium channel antibody is associated with chronic autonomic and sensory neuropathy.2013

    • Author(s)
      Kaneko K, Tano O, Kikuchi A, Hasegawa T, Tateyama M, Yoshioka M, Saito H, Watanabe O, Takeda A, Aoki M.
    • Journal Title

      J Neurol

      Volume: 260 Issue: 1 Pages: 315-317

    • DOI

      10.1007/s00415-012-6730-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-24659423, KAKENHI-PROJECT-25461286
  • [Journal Article] Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease : a 3 year longitudinal study2012

    • Author(s)
      Baba T, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, Takahashi S, Fukuda H, Aoki M, Itoyama Y, Mori E, Takeda A
    • Journal Title

      Brain

      Volume: 135 Pages: 161-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Journal Article] Suppression of dynamin GTPase decreases alpha-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.2012

    • Author(s)
      Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A.
    • Journal Title

      Mol Neurodegener

      Volume: 7 Issue: 1 Pages: 38-38

    • DOI

      10.1186/1750-1326-7-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23591266, KAKENHI-PROJECT-23790974, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390222, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-24111502
  • [Journal Article] Attentional Set-Shifting Deficit in Parkinson's Disease Is Associated with Prefrontal Dysfunction: An FDG-PET Study2012

    • Author(s)
      Yoichi Sawada, Yoshiyuki Nishio, Kyoko Suzuki, Kazumi Hirayama, Atsushi Takeda, Yoshiyuki Hosokai, Toshiyuki Ishioka, Yasuto Itoyama, Shoki Takahashi, Hiroshi Fukuda, Etsuro Mori
    • Journal Title

      PLoS ONE

      Volume: 7(6) Issue: 6 Pages: e38498-e38498

    • DOI

      10.1371/journal.pone.0038498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-22791104, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-23119703, KAKENHI-PUBLICLY-24111502
  • [Journal Article] Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia2012

    • Author(s)
      Hiraoka K, Okamura N, Funaki Y, Hayashi A, Tashiro M, Hisanaga K, Fujii T, Takeda A, Y anai K, Iwata R, Mori E
    • Journal Title

      Eur Neurol

      Volume: 68 Issue: 3 Pages: 137-143

    • DOI

      10.1159/000338774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390297, KAKENHI-PROJECT-23791388, KAKENHI-PROJECT-24300102, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24390278, KAKENHI-PROJECT-24659423, KAKENHI-PLANNED-21120007, KAKENHI-PUBLICLY-24111502
  • [Journal Article] Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease : a 3-year longitudinal study2012

    • Author(s)
      BabaT, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, et al
    • Journal Title

      Brain

      Volume: 135 Issue: 1 Pages: 162-169

    • DOI

      10.1093/brain/awr321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300345, KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-22791104, KAKENHI-PUBLICLY-23119703, KAKENHI-PUBLICLY-23135502, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-24390219, KAKENHI-PROJECT-24659423, KAKENHI-PUBLICLY-24111502
  • [Journal Article] Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson’s disease: a 3-year longitudinal study.2012

    • Author(s)
      Baba T, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, Takahashi S, Fukuda H, Aoki M, Itoyama Y, Mori E, Takeda A.
    • Journal Title

      Brain

      Volume: 135 Pages: 161-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2011

    • Author(s)
      Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A
    • Journal Title

      Parkinsonism & Related Disorders

      Volume: 17 Issue: 9 Pages: 698-700

    • DOI

      10.1016/j.parkreldis.2011.07.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23790974
  • [Journal Article] The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein.2011

    • Author(s)
      Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A.
    • Journal Title

      PLoS ONE

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] The AAA-A TPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of alpha-Synuclein2011

    • Author(s)
      Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A
    • Journal Title

      PLoS One

      Volume: 6 Issue: 12 Pages: 1-14

    • DOI

      10.1371/journal.pone.0029460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23790974
  • [Journal Article] Parkinson病の運動症状発症に先行する非運動症状 ー嗅覚障害ー2011

    • Author(s)
      馬場徹、菊池昭夫、長谷川隆文、武田篤
    • Journal Title

      神経内科

      Volume: 75 Pages: 319-323

    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] Association of olfactory dysfunction and brain. Metabolism in Parkinson’s disease.2011

    • Author(s)
      Baba T, Takeda A, Kikuchi A, Nishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, Mori E, Takahashi S, Fukuda H, Itoyama Y.
    • Journal Title

      Mov Disord

      Volume: 26 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] Differentiating Parkinson’s disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test.2011

    • Author(s)
      Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A.
    • Journal Title

      Parkinsonism Relat Disord

      Volume: 17 Pages: 698-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Journal Article] Association of olfactory dysfunction and brain metabolism in Parkinson's disease2011

    • Author(s)
      Baba T, Takeda A, Kikuchi A, Hishio Y, Hosokai Y, Hirayama K, Hasegawa T, Sugeno N, Suzuki K, et al
    • Journal Title

      Movement disorder

      Volume: 26 Issue: 4 Pages: 621-628

    • DOI

      10.1002/mds.23602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300345, KAKENHI-PROJECT-22611002, KAKENHI-PROJECT-22791104, KAKENHI-PUBLICLY-23135502, KAKENHI-PROJECT-23591228, KAKENHI-PROJECT-23790974
  • [Journal Article] Differentiating Parkinson's disease from multiple system atrophy by [(123)I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2011

    • Author(s)
      Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Takeda A
    • Journal Title

      Parkinsonism Relat Disord

      Volume: 17 Pages: 698-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Journal Article] Functional imaging studies of hyposmia in Parkinson's disease2010

    • Author(s)
      Takeda A., Saito N., Baba T., Kikuchi A., Sugeno N., Kobayashi M., Hasegawa T., Itoyama Y.
    • Journal Title

      J.Neurol.Sci. 289

      Pages: 36-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] In vivo visualization of α-synuclein deposition by carbon-11-labeled 2-(2-[2-dimethylaminothiazol-5-yl]ethenyl)-6-(2-[fluoro] ethoxy)benzoxazole positron emission tomography in multiple system atrophy2010

    • Author(s)
      Kikuchi A., Takeda A., Okamura N., Tashiro M., Hasegawa T., Furumoto S., Kobayashi M., Sugeno N., Baba T., Miki Y., Mori F., Wakabayashi K., Funaki Y., Iwata R., Takahashi S., Fukuda H., Arai H., Kudo Y., Yanai K, Itoyama Y.
    • Journal Title

      Brain (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease2009

    • Author(s)
      Satake W., Nakabayashi Y., Mizuta I., Hirota Y., Ito C., Kubo M., Kawaguchi T., Tsunoda T., Watanabe M., Takeda A., Tomiyama H., Nakashima K., Hasegawa K., Obata F., Yoshikawa T., Kawakami H., Sakoda S., Yamamoto M., Hattori N., Murata M., Nakamura Y., Toda T.
    • Journal Title

      Nature Genet. 41

      Pages: 1303-1307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] CSF protein biomarkers for proximal axonal damage improve prognostic accuracy in the acute phase of Guillain-Barre Syndrome2009

    • Author(s)
      Petzold A., Brettschneider J., Jin K., Keir G., Murray N.M.F., Hirsch N.P., Itoyama Y., Reilly M.M., Takeda A., Tumani H.
    • Journal Title

      Muscle Nerve 40

      Pages: 42-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Do parkinsonian patients have trouble telling lies? : The neurobiological basis of deceptive behavior2009

    • Author(s)
      Abe N., Fujii T., Hirayama K., Takeda A., Hosokai Y., Ishioka T., Nishio Y., Suzuki K., Itoyama Y., Takahashi S., Fukuda H., Mori E.
    • Journal Title

      Brain 132

      Pages: 1386-1395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment2009

    • Author(s)
      Hosokai Y., Nishio Y., Hirayama K., Takeda A., Ishioka T., Sawada Y., Suzuki K., Itoyama Y., Takahashi S., Fukuda H., Mori E.
    • Journal Title

      Mov.Disord. 24

      Pages: 854-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease2009

    • Author(s)
      Su B., Liu H., Wang X., Chen SG., Siedlak SL., Kondo E., Choi R., Takeda A., Castellani RJ., Perry G., Smith MA., Zhu X., Lee HG.
    • Journal Title

      Mol.Neurodeg. 4

      Pages: 32-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Narcolepsy as an initial manifestation of neuromyelitis optica with antiaquaporin-4 antibody2009

    • Author(s)
      Baba T., Nakashima I., Kanbayashi T., Konno M., Takahashi T., Fujihara K., Misu T., Takeda A., Shiga Y., Ogawa H., Itoyama Y.
    • Journal Title

      J.Neurol. 256

      Pages: 287-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Nucleic acid oxidation in Alzheimer disease2008

    • Author(s)
      Moreira PI., Nunomura A., Nakamura M., Takeda A., Shenk JC., Aliev G., Smith MA., Perry G.
    • Journal Title

      Free Radic Biol Med. 44

      Pages: 1493-505

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Ser129 phosphorylation of α-synuclein induces unfolded protein response mediated cell death2008

    • Author(s)
      Sugeno N., Takeda A., Hasegawa T., Kobayashi M., Kikuchi A., Mori F., Wakabayashi K., Itoyama Y.
    • Journal Title

      J.Biol Chem. 283:

      Pages: 23179-23188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Sublethal RNA oxidation as a mechanism for neurodegenerative disease2008

    • Author(s)
      Castellani RJ., Nunomura A., Rolston RK., Moreira PI., Takeda A., Perry G., Smith MA.
    • Journal Title

      Int.J.Mol.Sci. 9

      Pages: 789-806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] PARK9-linked parkinsonism in Eastern Asia : Mutation detection in ATP13A2 and clinical phenotype2008

    • Author(s)
      Ning YP, Kanai K., Tomiyama H., Li Y, Funayama M., Yoshino H, Sato S., Asahina M., Kuwabara S, Takeda A., Hattori T., Mizuno Y., Hattori N.
    • Journal Title

      Neurology 70

      Pages: 1491-1493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Ser129 phosphorylation of α-synuclein induces unfolded protein response mediated cell death2008

    • Author(s)
      Sugeno N., Takeda A., et.al.
    • Journal Title

      J. Biel Chem 238

      Pages: 23179-23188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites.2007

    • Author(s)
      Hasegawa T., Sugeno N., Takeda A., Matsuzaki-Kobayashi M., Kikuchi A., Furukawa K., Miyagi T., Itoyama Y.
    • Journal Title

      FEBS Lett. 581

      Pages: 406-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population.2007

    • Author(s)
      Satake W, Mizuta I, Suzuki S, Nakabayashi Y, Ito C, Watanabe M, Takeda A, Hasegawa K, Sakoda S, Yamamoto M, Hattori N, MurataM, Toda T.,
    • Journal Title

      Neuroreport 18

      Pages: 937-940

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] Olfactory dysfunction in Parkinson's disease.2007

    • Author(s)
      Takeda A., Kikuchi A., Itoyama Y.
    • Journal Title

      J. Neurol. 254(sup.4)

      Pages: 2-7

    • Data Source
      KAKENHI-PROJECT-19590978
  • [Journal Article] High ion permeability of plasma membrane caused by the α-synuclein mutations contributes to cellular degeneration.2006

    • Author(s)
      Furukawa K., M-Kobayashi M., Hasegawa T., Kikuchi A., Itoyama Y., Wang Y., Yao PJ., Bushlin I, Takeda A.
    • Journal Title

      J.Neurochem. (In press)

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Mechanisms of neuronal death in synucleinopathy2006

    • Author(s)
      Takeda A., Hasegawa A, Matsuzaki-Kobayashi M., Sugeno N., Kikuchi A., Itoyama Y., Furukawa K.
    • Journal Title

      J.Biomed.Biotech. (In press)

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Synergistic interaction between α-synuclein and oxidized catechol metabolites produced by tyrosinase : Implications for selective neurodegeneration in Parkinson's disease.2006

    • Author(s)
      Hasegawa T., Matsuzaki-Kobayashi M., Takeda A., Sugeno N., Kikuchi A., Furukawa K., Perry G, Smith MA., Itoyama Y.
    • Journal Title

      FEBS Lett. 580

      Pages: 2147-2152

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Tau modifiers as therapeutic targets for Alzheimer's disease.2005

    • Author(s)
      Liu Q., Lee HG., Honda K., Siedlak SL., Harris PL., Cash AD., Zhu X., Avila J., Nunomura A., Takeda A., et al.
    • Journal Title

      Biochim Biophys Acta 1739

      Pages: 211-215

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Alzheimer-specific epitopes of tau represent lipid peroxidation induced conformations.2005

    • Author(s)
      Liu Q, Smith MA, Avila J, DeBernardis J, Kansal M, Takeda A, et al.
    • Journal Title

      Free Radic Biol Med. 38

      Pages: 746-754

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Histochemical features of stress-induced aggregates in α-synuclein overexpression cells.2004

    • Author(s)
      Matsuzaki M., Hasegawa T., Takeda A., et al.
    • Journal Title

      Brain Researdch 1004

      Pages: 83-90

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Histochemical features of stress-induced aggregates in a-synuclein overexpressing cells.2004

    • Author(s)
      Matsuzaki M., Hasegawa T., Takeda A., Kikuchi A., Furukawa K., Kato Y., Itoyama Y.
    • Journal Title

      Brain Research 1004

      Pages: 83-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Accelerated formation of α-synuclein aggregates in differentiated SH-SY5Y neuroblastoma cells2004

    • Author(s)
      Hasegawa T., Matsuzaki M., Takeda A., et al.
    • Journal Title

      Brain Research 1013

      Pages: 51-59

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Histochemical features of stress-induced aggregates in α-synuclein overexpressing cells.2004

    • Author(s)
      Matsuzaki M., Hasegawa T., Takeda A., et al
    • Journal Title

      Brain Research 1004

      Pages: 83-90

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Heme catabolism and heme oxygenase in neurodegenerative disease.2004

    • Author(s)
      Takeda A., Itoyama Y., Kimpara T., et al.
    • Journal Title

      Antioxidants and Redox Signaling 6

      Pages: 888-894

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Tau modifiers as therapeutic targets for Alzheimer's disease2004

    • Author(s)
      Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Nunomura A, Takeda A, et al.
    • Journal Title

      Biochim Biophys Acta 1739

      Pages: 211-215

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Accelerated formation of a-synuclein aggregates in differentiated SH-SY5Y neuroblastoma cells.2004

    • Author(s)
      Hasegawa T., Matsuzaki M., Takeda A., Kikuchi A., Akita H., Perry G, Smith MA., Itoyama Y.
    • Journal Title

      Brain Research 1013

      Pages: 51-59

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease.2004

    • Author(s)
      Nunomura A., Chiba S., Lippa C.F., Cras P., Kalaria R.N., Takeda A., et al
    • Journal Title

      Neurobiology of Disease 17

      Pages: 108-114

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Accelerated formation of α-synuclein aggregates in differentiated SH-SY5Y neuroblastoma cells.2004

    • Author(s)
      Hasegawa T., Matsuzaki M., Takeda A., et al.
    • Journal Title

      Brain Research 1013

      Pages: 51-59

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with parkinsonism2004

    • Author(s)
      Kikuchi A, Takeda A, et al.
    • Journal Title

      Movement Disorders 19

      Pages: 590-593

    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.2003

    • Author(s)
      Tateyama M., Takeda A., Onodera Y., Matsuzaki M., Hasegawa T., Nunomura A., Hirai K., Perry G, Smith MA., Itoyama Y.
    • Journal Title

      Acta Neuropathologica 105

      Pages: 581-585

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.2003

    • Author(s)
      Tateyama M., Takeda A., et al.
    • Journal Title

      Acta Neuropathologica 105

      Pages: 581-585

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase.2003

    • Author(s)
      Hasegawa T., Matsuzaki M., Takeda A., Kikuchi A., Furukawa K., Shibahara S., Itoyama Y.
    • Journal Title

      J. Neurochem 87

      Pages: 470-475

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Journal Article] Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase.2003

    • Author(s)
      Hasegawa T., Matsuzaki M., Takeda A., et al.
    • Journal Title

      J. Neurochem. 87

      Pages: 470-475

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590874
  • [Presentation] 大脳皮質基底核症候群における18F-THK5351 PETの経時的変化2017

    • Author(s)
      菊池昭夫、江面道典、岡村信行、長谷川隆文、石木愛子、原田龍一、荒井啓行、谷内一彦、古本 祥三、田代 学、工藤幸司、武田 篤、青木正志
    • Organizer
      第36回日本認知症学会
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] 18F-THK5351 PET in corticobasal syndrome2017

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Ezura M, Baba T, Sugeno N, Yoshida S, Kobayashi J, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] Assessment of tau pathology in patients with corticobasal syndrome using 18F-THK5351 PET2016

    • Author(s)
      Kikuchi A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Toru Baba, Naoto Sugeno, Ryuji Oshima, Shun Yoshida, Junpei Kobayashi, Ezura M, Kobayashi M, Tano O, Mugikura S, Iwata R, Ishiki A, Furukawa K, Arai H, Furumoto S, Tashiro M, Yanai K, Kudo Y, Takeda A, Aoki M
    • Organizer
      The Movement Disorder Society's 20th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] パーキンソン病患者での[11C]BF-227 PETによるα-シヌクレイン蛋白凝集体の画像化2016

    • Author(s)
      菊池昭夫、岡村信行、馬場 徹、長谷川隆文、菅野直人、大嶋龍司、吉田隼、小林潤平、平岡宏太良、古本祥三、谷内一彦、田代 学、工藤幸司、武田 篤、青木正志
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸、神戸コンベンションセンター・神戸ポートピアホテル
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] 難治性の運動症状や非運動症状にどう対応するか?2015

    • Author(s)
      武田篤
    • Organizer
      第33回日本神経治療学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-11-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] [11C]BF-227 PETにおける多系統萎縮症脳内α-シヌクレインの経時的変化2015

    • Author(s)
      菊池昭夫、岡村信行、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、吉田隼、古本祥三、平岡宏太良、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      朱鷺メッセ (新潟)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] Longitudinal [11C]BF-227 PET study in MSA-C patients2015

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Furumoto S, Hasegawa T, Watanuki S, Hiraoka K, Funaki Y, Kobayashi M, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Yoshida S, Iwata R, Takahashi S, Fukuda H, Itoyama Y, Arai H, Kudo Y, Yanai K, Aoki M, Takeda A.
    • Organizer
      19th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-06-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] パーキンソン病に於けるコリン系と認知機能、そしてレビー小体型認知症との関連2015

    • Author(s)
      武田篤
    • Organizer
      第69回国立病院総合医学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-10-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化2015

    • Author(s)
      198)菊池 昭夫、馬場 徹、長谷川 隆文、菅野 直人、今野 昌俊、三浦 永美子、大嶋 龍司、岡村 信行、古本 祥三、谷内 一彦、田代 学、工藤 幸司、糸山 泰人、武田 篤、青木 正志
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Hyposmia and cholinergic deficiency in Parkinson Disease2014

    • Author(s)
      Takeda A.
    • Organizer
      The13th International Parkinson Disease Symposium in Takamatsu
    • Place of Presentation
      Takamatsu, Japan
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] K63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized alpha-synuclein2014

    • Author(s)
      Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A.
    • Organizer
      18th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      スウェーデン、ストックホルム
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] Severe hyposmia is a prodromal symptom of dementia in Parkinson disease2013

    • Author(s)
      Takeda A.
    • Organizer
      9th International congress on mental dysfunction & other non-motor features in Parkinson's disease and related disorders
    • Place of Presentation
      Seoul, South Korea
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in α-synuclein transgenic Drosophila.2013

    • Author(s)
      Hasegawa T, Konno M, Miura E, Sugeno N, Nagai Y, Fujikake N, Suzuki M, Kikuchi A, Aoki M, Takeda A.
    • Organizer
      The MDS 17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of alpha-synuclein2013

    • Author(s)
      Sugeno N. Hasegawa T. Konno M. Miura E. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] Severe hyposmia is a prodromal symptom of dementia in Parkinson disease2013

    • Author(s)
      Takeda A.
    • Organizer
      9th International congress on mental dysfunction & other non-motor features in Parkinson’s disease and related disorders
    • Place of Presentation
      Seoul, South Korea
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] In vivo visualization ofα-synuclein depositions in the human brain with multiple system atrophy and Parkinson's disease2013

    • Author(s)
      Kikuchi A., Takeda A.
    • Organizer
      1st Annual MJFF Alpha-Synuclein Imaging Summit
    • Place of Presentation
      New York, USA
    • Year and Date
      2013-11-08
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities inα-synuclein transgenic drosophila2013

    • Author(s)
      Hasegawa T., Konno M., Miura E., Sugeno N., Nagai Y., Fujikake N., Suzuki M., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Search for rare-variant risks of Parkinson's disease by sequencing of candidate genes and exome sequencing2013

    • Author(s)
      Satake W. Ando Y. Tomiyama H. Takeda A. Hasegawa K. Yamamoto M. Murata M. Hattori N. Toda T.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] Search for rare-variant risks of Parkinson's disease by sequencing of candidate genes and exome sequencing2013

    • Author(s)
      Satake W. Ando Y. Tomiyama H. Takeda A. Hasegawa K. Yamamoto M. Murata M. Hattori N. Toda T.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of alpha-synuclein2013

    • Author(s)
      Sugeno N. Hasegawa T. Konno M. Miura E. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Miura E. Hasegawa T. Konno M. Sugeno N. Kikuchi A. Baba T. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] The E3 ubiquitin ligase Nedd4 facilitates the endosomal targeting of extracellular alpha-synuclein.2013

    • Author(s)
      Sugeno N, Hasegawa T, Konno M, Miura E, Oshima R, Kikuchi A, Aoki M, Takeda A.
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of alpha-synuclein2013

    • Author(s)
      Sugeno N., Hasegawa T., Konno M., Miura E., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Differentiating Parkinson’s disease from multiple system atrophy by [123I]meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013

    • Author(s)
      Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Aoki M, Takeda A
    • Organizer
      The Movement Disorder Society's 17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Naoto Sugeno, Yoshitaka Nagai, Nobuhiro Fujikake, Mari Suzuki, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
    • Organizer
      AD/PD2013
    • Place of Presentation
      フローレンス、イタリア
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] E3 ubiquitin ligase Nedd4はαシヌクレインのエンドソームへのターゲッティングに重要である2013

    • Author(s)
      菅野直人、長谷川隆文、今野昌俊、三浦永美子、菊池昭夫、青木正志、武田篤
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京、東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in alpha-synuclein transgenic drosophila2013

    • Author(s)
      Hasegawa T, Konno M, Miura E, Sugeno N, Nagai Y, Fujikake N, Suzuki M, Kikuchi A, Aoki M, Takeda A
    • Organizer
      17th International Congress of Parkinson's Disease and Related Disorders
    • Place of Presentation
      シドニー,オーストラリア
    • Year and Date
      2013-06-17
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] ., RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      62) Miura E. Hasegawa T. Konno M. Sugeno N. Kikuchi A. Baba T. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] DNAJC6遺伝子異常によるパーキンソン病発症機序解析2013

    • Author(s)
      長谷川隆文、菅野直人、今野昌俊、三浦永美子、三好耕、浅沼幹人、菊池昭夫、青木正志、武田篤
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013

    • Author(s)
      Kikuchi A., Baba T., Hasegawa T., Sugeno N., Konno M., Aoki M., Takeda A.
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Hasegawa T, Konno M, Miura M, Suzuki M, Sugeno N, Nagai Y, Fujikake N, Kikuchi A, Aoki M, Takeda A.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Miura E. Hasegawa T. Konno M. Sugeno N. Kikuchi A. Baba T. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] パーキンソン病の嚥下障害と脳代謝の関係(縦断研究)2013

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、小林理子、菅野直人、今野昌俊、三浦永美子、西尾慶之、平山和美、鈴木匡子、青木正志、高橋昭喜、福田 寛、糸山泰人、森 悦朗、武田 篤
    • Organizer
      第7回日本パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Search for rare-variant risks of Parkinson's disease by sequencing of candidate genes and exome sequencing2013

    • Author(s)
      Satake W. Ando Y. Tomiyama H. Takeda A. Hasegawa K. Yamamoto M. Murata M. Hattori N. Toda T.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] E3 ubiquitin ligase Nedd4 is a key regulator of the endosomal targeting of a-synuclein2013

    • Author(s)
      Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      オーストラリア、シドニー
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] αSYN蓄積・神経変性におけるESCRT機能異常の関与2013

    • Author(s)
      大嶋龍司、長谷川隆文、田中伸幸、玉井恵一、菅野直人、三浦永美子、今野昌俊、菊池昭夫、青木正志、武田篤
    • Organizer
      第7回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] RNAi-mediated knockdown of VPS35 impairs α-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Hasegawa T, Konno M, Miura M, Suzuki M, Sugeno N, Nagai Y, Fujikake N, Kikuchi A, Aoki M, Takeda A.
    • Organizer
      XX World Congress on Parkinson's Disease and Related Disorders
    • Place of Presentation
      Geneva, Switzerland
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013

    • Author(s)
      Kikuchi A. Baba T. Hasegawa T. Sugeno N. Konno M. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of extracellular alpha-synuclein2013

    • Author(s)
      Naoto Sugeno, Takafumi Hasegawa, Masatoshi Konno, Emiko Miura, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] パーキンソン病の嚥下障害と脳代謝の関係(縦断研究)2013

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、小林理子、菅野直人、今野昌俊、三浦永美子、西尾慶之、平山和美、鈴木匡子、青木正志、高橋昭喜、福田 寛、糸山泰人、森 悦朗、武田 篤
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Search for rare-variant risks of Parkinson's disease by sequencing of candidate genes and exome sequencing2013

    • Author(s)
      Satake W., Ando Y., Tomiyama H., Takeda A., Hasegawa K., Yamamoto M., Murata M., Hattori N., Toda T.
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in α-synuclein transgenic drosophila2013

    • Author(s)
      Hasegawa T. Konno M. Miura E. Sugeno N. Nagai Y. Fujikake N. Suzuki M. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] αシヌクレイン細胞内取り込みはダイナミン阻害により抑制される2013

    • Author(s)
      長谷川隆文、今野昌俊、菅野直人、三浦永美子、菊池昭夫、青木正志、武田篤
    • Organizer
      平成24年度 運動失調症の病態解明と治療法開発に関する研究班班会議
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Differentiating Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013

    • Author(s)
      Kikuchi A. Baba T. Hasegawa T. Sugeno N. Konno M. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] RNAi-mediated knockdown of VPS35 impairsα-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Hasegawa T, Konno M, Miura E, Sugeno N, Nagai Y, Fujikake N, Suzuki M, Kikuchi A, Aoki M, Takeda A
    • Organizer
      The 11th International Conference on Alzheimer's & Parkinson's Diseases (AD/PD 2013)
    • Place of Presentation
      フローレンス,イタリア
    • Year and Date
      2013-03-07
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] ショウジョウバエモデルを用いたVPS35遺伝子異常によるパーキンソン病発症機構の解析2013

    • Author(s)
      今野昌俊、長谷川隆文、鈴木マリ、藤掛伸宏、永井義隆、三浦永美子、菅野直人、大嶋龍司、菊池昭夫、青木正志、武田篤
    • Organizer
      第7回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in α-synuclein transgenic drosophila2013

    • Author(s)
      Hasegawa T. Konno M. Miura E. Sugeno N. Nagai Y. Fujikake N. Suzuki M. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] RNAi-mediated silencing of VPS35 exacerbates phenotypic and locomotor abnormalities in α-synuclein transgenic drosophila2013

    • Author(s)
      Hasegawa T. Konno M. Miura E. Sugeno N. Nagai Y. Fujikake N. Suzuki M. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] RNAi-mediated knockdown of VPS35 impairsα-synuclein degradation by inhibiting the maturation of cathepsin D2013

    • Author(s)
      Miura E., Hasegawa T., Konno M., Sugeno N., Kikuchi A., Baba T., Aoki M., Takeda A.
    • Organizer
      17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] K63-linked ubiquitination by Nedd4 facilitates endosomal sequestration of internalized α-synuclein2013

    • Author(s)
      Naoto Sugeno, Takafumi Hasegawa, Ryuji Oshima, Nobuyuki Tanaka, Masashi Konno, Emiko Miura, Akio Kikuchi, Toru Baba, Mitsunori Fukuda, Tadashi Anan, Mitsuyoshi Nakao, Sven Geisler, Masashi Aoki and Atsushi Takeda
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      アメリカ合衆国、サン・ディエゴ
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] Severe hyposmia is a prodromal symptom of dementia in Parkinson disease2013

    • Author(s)
      Takeda A.
    • Organizer
      9th International congress on mental dysfunction & other non-motor features in Parkinson’s disease and related disorders
    • Place of Presentation
      Seoul, South Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Severe hyposmia is a prodromal symptom of dementia in Parkinson disease2013

    • Author(s)
      Takeda A.
    • Organizer
      9th International congress on mental dysfunction & other non-motor features in Parkinson’s disease and related disorders
    • Place of Presentation
      Seoul, South Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Nedd4 E3 ubiquitin ligase facilitates the endosomal targeting of alpha-synuclein2013

    • Author(s)
      Sugeno N. Hasegawa T. Konno M. Miura E. Kikuchi A. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] E3ユビキチンライゲースNedd4は細胞外αシヌクレインのエンドソームへのターゲッティングを制御する2013

    • Author(s)
      菅野直人、長谷川隆文、今野昌俊、三浦永美子、大嶋龍司、菊池昭夫、青木正志、武田篤
    • Organizer
      第7回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京、京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-25461264
  • [Presentation] Parkinson's disease from multiple system atrophy by [123I] meta-iodobenzylguanidine myocardial scintigraphy and olfactory test2013

    • Author(s)
      Kikuchi A. Baba T. Hasegawa T. Sugeno N. Konno M. Aoki M. Takeda A.
    • Organizer
      17th International Congress of Parkinson’s Disease and Movement Disorders, Sydney, Australia, 2013
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] レトロマー障害はカテプシンD成熟障害を介しα-シヌクレイン蓄積を誘導する2013

    • Author(s)
      三浦永美子、長谷川隆文、今野昌俊、菅野直人、大嶋龍司、菊池昭夫、青木正志、武田篤
    • Organizer
      第7回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Japanese 2nd GWAS identifies strong association at a novel risk locus and MCCC1 for Parkinson’s disease2012

    • Author(s)
      Satake W., Yamamoto K., Ando Y., Takeda A., et al.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] MIBG心筋シンチグラフィーと嗅覚テストによるパーキンソン病と多系統萎縮症の鑑別2012

    • Author(s)
      菊池昭夫、馬場徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、青木正志、武田篤
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Nedd4 participates in the internalization process of alpha-synuclein2012

    • Author(s)
      Sugeno N., Hasegawa T., Konno M., Miura E., Baba T., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Severe olfactory dysfunction is predictive of dementia associated with Parkinson's disease : A 3-year longitudinal study2012

    • Author(s)
      Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] The E3 ligase Nedd4 participates in the internalization process of alpha-synuclein2012

    • Author(s)
      Sugeno N., Hasegawa T., Konno M., Miura E., Baba T., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein2012

    • Author(s)
      Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Miura E., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] αシヌクレインのリソソーム移行および細胞外分泌はAAA型ATPase VPS4により制御される2012

    • Author(s)
      長谷川隆文、今野昌俊、三浦永美子、馬場徹、菅野直人、菊池昭夫、青木正志、武田篤
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Severe olfactory dysfunction is predictive of dementia associated with Parkinson’s disease: A 3-year longitudinal study2012

    • Author(s)
      Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] The AAA-ATPase VPS4 regulates Extracellular Secretion and Lysosomal Targeting of Alpha-synuclein2012

    • Author(s)
      Hasegawa T., Konno M, Baba T, Sugeno N, Kikuchi A, Miura E, Takeda A
    • Organizer
      NRF-JSPS Asian Science Seminar
    • Place of Presentation
      ソウル,韓国
    • Year and Date
      2012-02-14
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Neural basis of memory impairment in Parkinson's disease: A longitudinal PET study2012

    • Author(s)
      Shoji Y., Nishio Y, Takeda A., Uchiyama M., Kashinoura T., Hosokai Y., Fukuda H., Mori E.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Japanese 2nd GWAS identifies strong association at a novel risk locus and MCCC1 for Parkinson's disease2012

    • Author(s)
      Satake W., Yamamoto K., Ando Y., Takeda A., Tomiyama H., Kawakami H., Hasegawa K., Obata F., Watanabe M., Tamaoka A., Nakashima K., Sakoda S., Yamamoto M., Hattori N., Murata M., Nakamura Y., Toda T.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Neural basis of memory impairment in Parkinson’s disease: A longitudinal PET study2012

    • Author(s)
      Shoji Y., Nishio Y., Takeda A., Uchiyama M., Kashinoura T., Hosokai Y., Fukuda H., Mori E.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Neural basis of memory impairment in Parkinson’s disease: A longitudinal PET study2012

    • Author(s)
      Shoji Y., Nishio Y., Takeda A., Uchiyama M., Kashinoura T., Hosokai Y., Fukuda H., Mori E.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] Nedd4 participates in the internalization process of alpha-synuclein2012

    • Author(s)
      Sugeno N., Hasegawa T., Konno M., Miura E., Baba T., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein2012

    • Author(s)
      Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Miura E., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] Suppression of Dynamin GTPase Activity Decreases α-synuclein Uptake in Neuronal and Oligodendroglial Cells2012

    • Author(s)
      Takafumi Hasegawa, Masatoshi Konno, Naoto Sugeno, Emiko Miura, Toru Baba, Akio Kikuchi, Masashi Aoki, Atsushi Takeda
    • Organizer
      第17回武田科学振興財団 生命科学シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of Alpha-synuclein2012

    • Author(s)
      Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Miura E, Takeda A
    • Organizer
      NRF-JSPS Asian Science Seminar 2012
    • Place of Presentation
      ソウル、韓国
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein2012

    • Author(s)
      Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Miura E., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting ofα-synuclein2012

    • Author(s)
      Hasegawa T., Konno M., Baba T., Sugeno N., Kikuchi A., Miura E., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] MIBG心筋シンチグラフィーと嗅覚テストによるパーキンソン病と多系統萎縮症の鑑別2012

    • Author(s)
      菊池昭夫、馬場徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、青木正志、武田篤
    • Organizer
      第6回日本パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Severe olfactory dysfunction is predictive of dementia associated with Parkinson’s disease: A 3-year longitudinal study2012

    • Author(s)
      Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Dynamin GTPase activity decreases alpha-synuclein uptake in neuronal and oligodendroglial cells2012

    • Author(s)
      Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Neural basis of memory impairment in Parkinson's disease : A longitudinal PET study2012

    • Author(s)
      Shoji Y., Nishio Y., Takeda A., Uchiyama M., Kashinoura T., Hosokai Y., Fukuda H., Mori E.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] ショウジョウバエモデルを用いたVps35遺伝子異常によるパーキンソン病病態の解析2012

    • Author(s)
      長谷川隆文、今野昌俊、三浦永美子、菅野直人、永井義隆、藤掛伸宏、鈴木マリ、菊池昭夫、馬場徹、青木正志、武田篤
    • Organizer
      平成24年度 第6回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Dynamin GTPase activity decreases alpha-synuclein uptake in neuronal and oligodendroglial cells2012

    • Author(s)
      Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Dynamin GTPase activity decreases alpha-synuclein uptake in neuronal and oligodendroglial cells2012

    • Author(s)
      Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-06-17
    • Data Source
      KAKENHI-PUBLICLY-24111502
  • [Presentation] Japanese 2nd GWAS identifies strong association at a novel risk locus and MCCC1 for Parkinson’s disease2012

    • Author(s)
      Satake W., Yamamoto K., Ando Y., Takeda A., et al.
    • Organizer
      16th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Severe olfactory dysfunction is predictive of dementia associated with Parkinson's disease : A 3-year longitudinal study2012

    • Author(s)
      Baba T., Kikuchi A., Hirayama K., Nishio Y., Hosokai Y., Kanno S., Hasegawa T., Sugeno N., Konno M., Miura E., Mori E., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Japanese 2nd GWAS identifies strong association at a novel risk locus and MCCC1 for Parkinson's disease2012

    • Author(s)
      Satake W., Yamamoto K, Ando Y., Takeda A., Tomiyama H., Kawakami H., Hasegawa K., Obata F., Watanabe M., Tamaoka A., Nakashima K., Sakoda S., Yamamoto M., Hattori N., Murata M., Nakamura Y., Toda T.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] αシヌクレイン細胞間伝播はダイナミン機能阻害により抑制される2012

    • Author(s)
      長谷川隆文、今野昌俊、三浦永美子、菅野直人、菊池昭夫、青木正志、武田篤
    • Organizer
      第30回 日本神経治療学会総会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Dynamin GTPase activity decreases alpha-synuclein uptake in neuronal and oligodendroglial cells2012

    • Author(s)
      Konno M., Hasegawa T., Baba T., Miura E., Sugeno N., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24659423
  • [Presentation] Suppression of Dynamin GTPase Activity Decreasesα-synuclein Uptake in Neuronal and Oligodendroglial Cells2012

    • Author(s)
      Hasegawa T, Konno M, Sugeno N, Miura E, Baba T, Kikuchi A, Aoki M, Takeda A
    • Organizer
      The 17th Takeda Science Foundation Symposium on Bioscience."Therapeutic Approach for Neurodegenerative Diseases : Focusing on Alzheimer & Parkinson Diseases"
    • Place of Presentation
      大阪
    • Year and Date
      2012-12-07
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Nedd4 participates in the internalization process of alpha-synuclein2012

    • Author(s)
      Sugeno N., Hasegawa T., Konno M., Miura E., Baba T., Kikuchi A., Aoki M., Takeda A.
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-synuclein2012

    • Author(s)
      Takafumi Hasegawa, Masatoshi Konno, Toru Baba, Naoto Sugeno, Akio Kikuchi, Emiko Miura, Atsushi Takeda
    • Organizer
      16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      ダブリン、アイルランド
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting ofα-synuclein2012

    • Author(s)
      Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Miura E, Takeda A
    • Organizer
      The 16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      ダブリン,アイルランド
    • Year and Date
      2012-06-18
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] Role of TPPP/p25 on alpha-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy2011

    • Author(s)
      Hasegawa T, Baba T, Michiko Kobayashi, Konno M, Sugeno N, Kikuchi A, Takeda A
    • Organizer
      15th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      トロント、カナダ
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] MVB sorting機構はα-synuclein分泌・ライソゾーム移行に関与する2011

    • Author(s)
      長谷川 隆文、今野 昌俊、馬場 徹、菅野 直人、菊池 昭夫、若林 孝一、武田 篤
    • Organizer
      第5回パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] 培養細胞系を用いたα-synucleinプリオン仮説の分子病態解析2011

    • Author(s)
      長谷川隆文、今野昌俊、馬場徹、菅野直人、菊池昭夫、武田篤
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] アルファシヌクレインの細胞外分泌・ライソゾーム移行を制御する細胞内膜動輸送系の探索2011

    • Author(s)
      長谷川隆文、今野 昌俊、馬場 徹、菅野 直人、菊池 昭夫、武田 篤
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591228
  • [Presentation] GCI形成過程における Tubulin polymerization promoting protein の機能的役割2009

    • Author(s)
      小林理子, 長谷川隆文, 武田篤, 菅野直人, 菊池昭夫, 馬場徹, 糸山泰人
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] 嗅覚異常、シンポジウム「パーキンソン病の診断をめぐる新機軸」2009

    • Author(s)
      武田篤
    • Organizer
      第62回日本自律神経学会
    • Place of Presentation
      和歌山
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病患者における嗅覚障害の神経基盤の検討2009

    • Author(s)
      馬場徹, 菅野直人, 小林理子, 菊池昭夫, 長谷川隆文, 武田篤, 糸山泰人, 平山一美, 森悦朗
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] レビー小体がなければパーキンソン病とはいえない・Yes2009

    • Author(s)
      武田篤
    • Organizer
      第3回MDSJ
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Cytoprotective effects of extracellular dopamine under the dopamine overproduction2009

    • Author(s)
      Sugeno N., Kobayashi M., Hasegawa T., Takeda A., Kikuchi A., Baba T., Itoyama Y.
    • Organizer
      13th International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] チロシン水酸化酵素発現細胞における細胞死2009

    • Author(s)
      菅野直人, 小林理子, 武田篤, 長谷川隆文, 菊池昭夫, 馬場徹, 糸山泰人
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病の病態:運動症候と非運動症候2009

    • Author(s)
      武田篤, 他
    • Organizer
      第51回 日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Dopamine Dysregulation Syndrome、シンポジウム「PD・DLBの認知・行動障害」2009

    • Author(s)
      武田篤
    • Organizer
      第14回日本精神神経医学会
    • Place of Presentation
      仙台
    • Year and Date
      2009-11-05
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Changes in brain metabolism and dysphagia in Parkinson's disease2009

    • Author(s)
      Kikuchi A., Takeda A., Baba, T. Sugeno N., Kobayashi M., Hasegawa T., Mori E., Itoyama Y.
    • Organizer
      13th International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病の病態 : 運動症候と非運動症候、シンポジウム「パーキンソン病の病因・診断・治療研究の進歩」2009

    • Author(s)
      武田篤
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] 痙性斜頚患者における脳代謝の検討2009

    • Author(s)
      菊池昭夫, 武田篤, 馬場徹, 菅野直人, 小林理子, 長谷川隆文, 田代学, 四月朔日聖一, 伊藤正敏, 関和則, 糸山泰人
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Changes in brain metabolism and hyposmia in Parkinson's disease2009

    • Author(s)
      Baba T., Takeda A., Kikuchi A., Sugeno N., Kobayashi M., Hasegawa T., Hirayama K., Mori E., Itoyama Y.
    • Organizer
      13th International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病におけるαSYN自己抗体の存在およびオリゴマークリアランスへの関与2009

    • Author(s)
      長谷川隆文, 武田篤, 菊池昭夫, 菅野直人, 小林理子, 馬場徹, 糸山泰人
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Hyposomnia in Parkinson's disease is associated with changes in cortical metabolism2008

    • Author(s)
      Takeda A., Kikuchi A., Sugeno N., Kobayashi M., Hirayama K., Mori E., Itoyama Y.
    • Organizer
      12th International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病の錯綜図認知障害と脳代謝2008

    • Author(s)
      平山和美, 石岡俊之, 武田篤, 細貝良行, 鈴木匡子, 西尾憲之, 糸山泰人, 福田寛, 森悦朗
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Ser129 phosphorylation of α-synuclein induces unfolded protein response mediated cell death2008

    • Author(s)
      Sugeno N., Takeda A., et.al.
    • Organizer
      12^<th> International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2008-06-25
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] 軽度認知障害を有するパーキンソン病患者における大脳局所灰白質量減少2008

    • Author(s)
      西尾憲之, 武田篤, 平山和美, 鈴木匡子, 細貝良行, 石岡俊之, 糸山泰人, 森悦朗
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Ser129 phosphorylation of α-synuclein induces unfolded protein response mediated cell death2008

    • Author(s)
      Sugeno N., Takeda A., Hasegawa T., Kobayashi M., Kikuchi A., Itoyama Y.
    • Organizer
      12th International congress of Parkinson's disease and movement disorders
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Lewy 小体は善玉である・YES2008

    • Author(s)
      武田篤
    • Organizer
      第2回MDSJ
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病患者における嚥下障害と脳代謝の検討2008

    • Author(s)
      菊池昭夫, 武田篤, 菅野直人, 小林理子, 長谷川隆文, 細貝良行, 石岡俊之, 西尾憲之, 岡田和枝, 平山和美, 鈴木匡子, 森悦朗, 金田朋洋, 高橋昭喜, 福田寛, 糸山泰人
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] Wearing-off の機序とその評価、イブニングセミナー「PD治療におけるL-dopa療法を再考する」2008

    • Author(s)
      武田篤
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病の病態 : 分子生物学から分かったこと. シンポジウム「パーキンソン病の臨床、基礎の最前線」2008

    • Author(s)
      武田篤
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病感受性遺伝子の同定-FGF20と新規感受性遺伝子-2008

    • Author(s)
      佐竹渉, 水田依久子, 渡邉雅彦, 武田篤, 長谷川一子, 中島健二, 佐古田三郎, 山本光利, 服部信孝, 村田美穂, 戸田達史
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] αシヌクレインリン酸化によって誘導される細胞死は小胞体ストレスを介する2008

    • Author(s)
      菅野直人, 武田篤, 小林理子, 菊池昭夫, 長谷川隆文, 糸山泰人
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病感受性遺伝子の同定および統計学的相互作用解析2008

    • Author(s)
      水田依久子, 佐竹渉, 角田達彦, 渡邉雅彦, 武田篤, 長谷川一子, 中島健二, 山本光利, 服部信孝, 村田美穂, 戸田達史
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] ドパミン過剰産生細胞を用いた細胞死メカニズムの検討 : 酸化的ストレスとの関連2008

    • Author(s)
      小林理子, 菅野直人, 武田篤, 菊池昭夫, 糸山泰人
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] PET and fMRI of Olfaction in PD2008

    • Author(s)
      Takeda A.
    • Organizer
      6th International Congress on mental dysfunctions & other non-motor features in Parkinson's disease
    • Place of Presentation
      Dresden, Germany
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病患者における嗅覚低下と脳代謝の検討2008

    • Author(s)
      武田篤, 菊池昭夫, 菅野直人, 小林理子, 平山和美, 森悦朗, 糸山泰人
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19590978
  • [Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化.

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、岡村信行、古本祥三、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] パーキンソン病における脳内α-シヌクレイン蛋白凝集体のPETによる画像化.

    • Author(s)
      菊池昭夫、馬場 徹、長谷川隆文、菅野直人、今野昌俊、三浦永美子、大嶋龍司、岡村信行、古本祥三、谷内一彦、田代 学、工藤幸司、糸山泰人、武田 篤、青木正志.
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] Exome sequencing of Parkinson's disease in order to identify genetic variants with high disease-risk

    • Author(s)
      Satake W. Ando Y. Tomiyama H. Kashihara K. Mochizuki H. Murayama S. Takeda A. Hasegawa K. Tsuji S. Yamamoto M. Murata M. Hattori N. Toda T.
    • Organizer
      18th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-07 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Functional ESCRT machinery is required for the clearance of aggregate-prone proteins associated with neurodegenerative diseases

    • Author(s)
      Oshima R. Hasegawa T. Sugeno N. Konno M. Miura E. Kikuchi A. Tamai K. Takeda A. Tanaka N. Aoki M.
    • Organizer
      18th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-07 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] [11C] BF-227 PET can visualize in vivo α-synuclein deposition in Parkinson’s disease.

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Hasegawa T, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Furumoto S, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Aoki M, Itoyama Y, Takeda A.
    • Organizer
      18th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-26461303
  • [Presentation] In vivo visualization of α-synuclein deposition by carbon-11-labeled 2-(2-[2-dimethylaminothiazol-5-yl]ethenyl)−6-(2-[fluoro]ethoxy)benzoxazole positron emission tomography in Parkinson's disease

    • Author(s)
      Kikuchi A. Okamura N. Tashiro M. Hasegawa T. Sugeno N. Baba T. Konno M. Miura E. Oshima R. Furumoto S. Funaki Y. Iwata R. Takahashi S. Fukuda H. Arai H. Kudo Y. Yanai K. Itoyama Y. Aoki M. Takeda A.
    • Organizer
      18th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-07 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Hot Topics in Parkinson Disease

    • Author(s)
      Takeda A.
    • Organizer
      The14th International Parkinson Disease Symposium in Takamatsu
    • Place of Presentation
      Takamatsu, Japan
    • Year and Date
      2015-02-27 – 2015-03-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] [11C] BF-227 PET can visualize in vivo α-synuclein deposition in Parkinson’s disease.

    • Author(s)
      Kikuchi A, Okamura N, Tashiro M, Hasegawa T, Sugeno N, Baba T, Konno M, Miura E, Oshima R, Furumoto S, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Aoki M, Itoyama Y, Takeda A.
    • Organizer
      18th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-23591266
  • [Presentation] K63-linked ubiquitination by Nedd4 facilitates endosomal sequestration of internalized alpha-synuclein, 18th International Congress of Parkinson’s Disease and Movement Disorders

    • Author(s)
      Sugeno N. Hasegawa T. Tanaka N. Oshima R. Konno M. Miura E. Kikuchi A. Baba T. Fukuda M. Geisler S. Aoki M. Takeda A.,
    • Organizer
      18th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-07 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-24390219
  • [Presentation] Cognitive impairment in multiple system atrophy: A position statement by the neuropsychology task force of the MDS multiple system atrophy (MODIMSA) study group

    • Author(s)
      Stankovic I. Krismer F. Jesic A. Antonini A. Benke T. Brown R.G. Burn D.J. Holton J.L. Kaufmann H. Kostic V.S. Ling H. Meissner W.G. Poewe W. Semnic M. Seppi K. Takeda A. Weintraub D. Wenning G.K.
    • Organizer
      18th International Congress of Parkinson’s Disease and Movement Disorders
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-07 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-24390219
  • 1.  HASEGAWA Takafumi (70361079)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 58 results
  • 2.  KIKUCHI Akio (80463785)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 38 results
  • 3.  OKAMURA Nobuyuki (40361076)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 4.  FURUMOTO Shozo (00375198)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 5.  TASHIRO Manabu (00333477)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 6.  FUNAKI Yoshihito (50261491)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 7.  菅野 直人 (30509550)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 23 results
  • 8.  NAGAI Yoshitaka (60335354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 9.  TAMAI Makoto (90004720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OHKI Kazuo (80115394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ISHIGURO Sei-ichi (20111271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAKAMURA Shozo (80108498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ITOYAMA Yasuto (30136428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  竪山 真規
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  HOSOKAI Yoshiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 16.  青木 正志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  石岡 俊之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  若林 孝一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  森 文秋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  鈴木 匡子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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