Kaneda Toshio 金田利夫

… Alternative Names

KANEDA Toshio 金田利夫

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Researcher Number	70339521
Other IDs
External Links
Affiliation (Current)	2025: 星薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 星薬科大学, 薬学部, 准教授 2015: 星薬科大学, 薬学部, 講師 2014 – 2015: 星薬科大学, 薬学部, 准教授 2013: 星薬科大学, 薬学部, 講師 2010 – 2011: 星薬科大学, 薬学部, 講師 … More 2006: 星薬科大学, 薬学部, 助教授 2006: 星薬科大学, 薬学部・病態整理学教室, 助教 2003 – 2005: 星薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Natural medicines Except Principal Investigator Morphological basic dentistry / Biological pharmacy / Experimental pathology
Keywords	Principal Investigator 天然物 / がん / PD-1 / 免疫賦活作用 / 漢方薬 / 免疫賦活物質 / B細胞 / ニワトコ / 免疫賦活 / アルカロイド … More / 平滑筋弛緩 / TRPC6 / TRPチャネル / TRPC / 平滑筋 / 血管弛緩 / vasodilation / TRP channel / decipic acid / alkaloid … More Except Principal Investigator TGF-β / RANKL / beta ig-h3 / 骨芽細胞 / 破骨細胞形成 / シグナル伝達 / 癌 / 転写因子 / 薬学 / ユビキチン・リガーゼ / PML-RARα / 白血病 / osteopontin / integrin / RGD sequence / osteoclast progenitors / osteoclastogenesis / 骨吸収 / 接着タンパク / オステオポンチン / インテグリン / RGD配列 / 破骨細胞前駆細胞 / 破骨細胞分化 / Transgenic mice / Animal model / Graves' disease / Anti-TSH receptor antibody / TSH receptor / エレクトロポレーション / トランスジェニックマウス / モデルマウス / バセドウ病 / 抗TSH受容体抗体 / TSH受容体 / RANKL産生 / 細胞融合 / 炎症性骨吸収 / LOX-1 / 破骨細胞 / 炎症性骨破壊 / 分泌機構 / 細胞融合タンパク質 / ノックアウトマウス / scavenger receptor / LDL受容体 / caveolin-1 Less

A study of searching for immunostimulating natural productsPrincipal Investigator
- Principal Investigator
  
  Kaneda Toshio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Hoshi University
The elucidation of the role of lipid in bone resorption of inflammatory bone diseases; in particular, the exploration of the role of LOX-1 as an oxidized LDL receptor
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Research for natural products including alkaloids that inhibit TRP channelsPrincipal Investigator
- Principal Investigator
  
  Kaneda Toshio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Hoshi University
DEPENDENCY OF OSTEOCLAST DIFFERENTIATION ON EXOGENOUS CHOLESTEROL AND ROLE OF CAVEOLIN-1 IN OSTEOCLASTOGENESIS
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
白血病発症におけるE3ユビキチン・リガーゼの機能解析とその臨床応用
- Principal Investigator
  
  武藤章弘
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Study on the immunological mechanism of anti-TSH receptor antibody production by using transgenic mice
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hoshi University Faculty of Pharmaceutical Science
Elucidation of role of beta ig-3 derived from osteoclasts in bone resorption and formation
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University

All 2015 2013 2012 2004 2003 Other

All Journal Article Presentation

[Journal Article] Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.2015
- Author(s)
  Nakayachi M, Ito J, Hayashida C, Ohyama Y, Kakino A, Okayasu M, Sato T, Ogasawara T, Kaneda T, Suda N, Sawamura T, Hakeda Y
- Journal Title
  
  Bone. 75:170-182
  
  Volume: 75 Pages: 170-182
- DOI
  10.1016/j.bone.2015.02.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659916, KAKENHI-PROJECT-25293422, KAKENHI-PROJECT-26870540, KAKENHI-PROJECT-26463085, KAKENHI-PROJECT-15K15759, KAKENHI-PROJECT-26670895, KAKENHI-PROJECT-25293376
[Journal Article] Vasorelaxant effects on rat aortic artery by two types of indole alkaloids, naucline and cadamine2013
- Author(s)
  Mineri Ishizuka, Ikumi Koga, Kazumasa Zaima, Toshio Kaneda, Yusuke Hirasawa, A. Hamid A. Hadi, Hiroshi Morita
- Journal Title
  
  J. Nat. Med.
  
  Volume: 67 Issue: 2 Pages: 399-403
- DOI
  10.1007/s11418-012-0689-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460139, KAKENHI-PROJECT-25460140
[Journal Article] Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice due to a defect in osteoclasticcell-cell fusion2012
- Author(s)
  Okayasu M, Nakayachi M, Hayashida C, Ito J, Kaneda T, Masuhara M, Suda N, Sato T, Hakeda Y
- Journal Title
  
  J Biol Chem
  
  Volume: (In press) Issue: 23 Pages: 19229-19241
- DOI
  10.1074/jbc.m111.323600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592341, KAKENHI-PROJECT-22791792, KAKENHI-PROJECT-23593018, KAKENHI-PROJECT-24593079
[Journal Article] Receptor activator of NF-kB ligand-dependent expression of caveolin-1 in osteoclast precursors and high dependency of osteoclastogenesis on exogenous lipoprotein2012
- Author(s)
  Hada N, Okayasu M, Ito J, Nakayachi M, Hayashida C, Kaneda T, Uchida N, Muramatsu T, Koike C, Masuhara M, Sato T, Hakeda Y
- Journal Title
  
  Bone
  
  Volume: 50 Pages: 226-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592341
[Journal Article] The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage2004
- Author(s)
  Kobayashi Y, Ueyama S, Arai Y, Yoshida Y, Kaneda T, Sato T, Shin K, Kumegawa M, Hakeda Y
- Journal Title
  
  J. Bone Miner. Metab. 22
  
  Pages: 318-328
- NAID
  10013606023
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591946
[Journal Article] The active metabolite of lefluonomide, A771726,inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.2004
- Author(s)
  Kobayashi, Y., Ueyama, S., Arai, Y., Yoshida, Y., Kaneda, T., Sato, T., Shin, K., Kumegawa, M., Hakeda, Y.
- Journal Title
  
  J.Bone Miner.Metab. 22
  
  Pages: 318-328
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591946
[Journal Article] Dexamethasone enhances osteoclast formation synergistically with transforming growth factor-b by stimulating the priming of osteolast progenitors for differentiation into osteoclasts.2003
- Author(s)
  Takuma, A., Kaneda, T., Sato, T., Ninomiya, S., Kumegawa, M., Hakeda, Y.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 44667-44674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591946
[Journal Article] Dexamethasone enhances osteoclast formation synergistically with transforming growth factor-b by stimulating the priming of osteoclast progenitors for differentiation into osteoclasts2003
- Author(s)
  Takuma A, Kaneda T, Sato T, Ninomiya S, Kumegawa M, Hakeda Y
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 44667-44674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591946
[Presentation] Vasorelaxant Activity of Chromanones from Calophyllum scriblitifolium Bark on Rat Aortic Artery2015
- Author(s)
  F. Ifadotunnikmah, T. Sasaki, A. E. Nugroho, Y. Hirasawa, T. Kaneda, A. H. A. Hadi, H. Morita
- Organizer
  Inaugural Symposium of the Phytochemical Society of Asia 2015
- Place of Presentation
  徳島
- Year and Date
  2015-08-30
- Data Source
  KAKENHI-PROJECT-25460140
[Presentation] オトギリソウ科Calophyllum scriblitifoliumより単離したクロマノン類の血管平滑筋弛緩作用2013
- Author(s)
  佐々木忠裕、Alfarius Eco Nugroho、石塚美練里、光田恵里香、房梁、平澤祐介、金田利夫、森田博史、A. Hamid A.Hadi
- Organizer
  日本生薬学会
- Place of Presentation
  北海道医療大学
- Data Source
  KAKENHI-PROJECT-25460140
[Presentation] Indole Alkaloids from Tabernaemontana corymbosa
- Author(s)
  Alfarius Eco Nagroho、馬上未帆、金田利夫、A.Hamid A Hadi、森田博史
- Organizer
  日本生薬学会
- Place of Presentation
  福岡大学
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25460140
[Presentation] Calophyllum scriblitfolium より単離したクロマノン類の絶対立体配置
- Author(s)
  佐々木忠裕、Alfarius Eco Nagroho、平澤祐介、金田利夫、A.Hamid A Hadi、森田博史
- Organizer
  日本生薬学会
- Place of Presentation
  福岡大学
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25460140

1. HAKEDA Yoshiyuki (90164772)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. SATO Takuya (00316689)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. MASUHARA Masaaki (70372901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. YOSHIDA Tadashi (00182767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MUTO Akihiro (90239468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OKAYASU Mari (10610941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OGASAWARA Toru (20359623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITO Junta (40609096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAYASHIDA Chiyomi (40710900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORITA Hiroshi (70220069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 木崎昌弘 (20161432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ヌグロホアルファリウス・エコ (40770029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 須田直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kaneda Toshio 金田 利夫

KANEDA Toshio 金田 利夫

Research Projects

Research Products

Co-Researchers

A study of searching for immunostimulating natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The elucidation of the role of lipid in bone resorption of inflammatory bone diseases; in particular, the exploration of the role of LOX-1 as an oxidized LDL receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for natural products including alkaloids that inhibit TRP channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEPENDENCY OF OSTEOCLAST DIFFERENTIATION ON EXOGENOUS CHOLESTEROL AND ROLE OF CAVEOLIN-1 IN OSTEOCLASTOGENESIS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

白血病発症におけるE3ユビキチン・リガーゼの機能解析とその臨床応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the immunological mechanism of anti-TSH receptor antibody production by using transgenic mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of role of beta ig-3 derived from osteoclasts in bone resorption and formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vasorelaxant effects on rat aortic artery by two types of indole alkaloids, naucline and cadamine2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low-density lipoprotein receptor deficiency causes impaired osteoclastogenesis and increased bone mass in mice due to a defect in osteoclasticcell-cell fusion2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Receptor activator of NF-kB ligand-dependent expression of caveolin-1 in osteoclast precursors and high dependency of osteoclastogenesis on exogenous lipoprotein2012

Author(s)

Journal Title

Data Source

[Journal Article] The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] The active metabolite of lefluonomide, A771726,inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Dexamethasone enhances osteoclast formation synergistically with transforming growth factor-b by stimulating the priming of osteolast progenitors for differentiation into osteoclasts.2003

Author(s)

Journal Title

Kaneda Toshio 金田利夫

KANEDA Toshio 金田利夫