Suzuki Takafumi 鈴木隆史

… Alternative Names

SUZUKI Takafumi 鈴木隆史

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Researcher Number	70508308
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 東北大学, 医学系研究科, 准教授 2021 – 2023: 東北大学, 医学系研究科, 准教授 2016 – 2021: 東北大学, 医学系研究科, 講師 2017: 東北大学, 医学(系)研究科(研究院), 講師 2012 – 2015: 東北大学, 医学(系)研究科(研究院), 助教 … More 2011: 東北大学, 医学系研究科, 助教 2008 – 2011: Tohoku University, 大学院・医学系研究科, 助教 2010: 東北大学, 大学院・医学(系)研究科, 助教 2009: Tohoku University, 医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48040:Medical biochemistry-related / Biological Sciences / Transformative Research Areas, Section (IV) Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Medium-sized Section 48:Biomedical structure and function and related fields / Broad Section H / Risk sciences of radiation and chemicals / Biological Sciences / Hematology
Keywords	Principal Investigator Nrf2 / Keap1 / ストレス / ストレス応答 / 含セレン蛋白質 / センサー / 宇宙環境ストレス / 宇宙ストレス / 発現制御 / 遺伝子 … More / 過酸化水素 / 腎性尿崩症 / ユビキチンライゲース / ユビキチン化制御 / ストレスセンサー / がん / 酸化ストレス防御機構 / ミエロイド系細胞 / がん転移 / 含セレン酵素群 / 神経変性 / 抗酸化酵素 / 酸化ストレス / SeCys-tRNA / システイン残基 / トランスジェニックマウス / 転写因子 … More Except Principal Investigator 酸化ストレス / 活性酸素 / Keap1 / Nrf2 / 転写因子 / 環境 / 環境応答 / 分子動力学シミュレーション / 構造生物学 / ナトリウムチャネル / 局所麻酔薬 / KEAP1-NRF2系 / 健康長寿 / 加齢関連疾患 / Keap1-Nrf2制御系 / ストレス応答 / 細胞･組織 / Mrf2 / 細胞・組織 / 遺伝子組換えマウス / DNA損傷 / 突然変異 / アポトーシス / MIS応答 / 皮膚 / 紫外線 / ヘムオキシゲナーゼ１ / プロテオスタシス / ATF4 / GCN1L1 / eIF2alpha / 酸素ストレス / プロテアソーム / ミトコンドリア / 細胞の老化 / 癌化 / 細胞周期 / 転写制御 / 造血幹細胞 / 遺伝子 / ストレス / 発現制御 / エリスロポエチン / 低酸素 Less

KEAP1-NRF2制御系による多様な環境ストレス感知機構の分子基盤解明Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
宇宙環境ストレス応答の理解から挑む加齢性疾患の克服Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Tohoku University
Keap1-Nrf2制御系によるストレス応答の動的構造基盤の解明Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
Development of Adverse Events-free Local Anesthetics in Cryo-EM Structural Determination of Sodium Channels
- Principal Investigator
  
  Yamauchi Masanori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tohoku University
Regulation of transcription factor Nrf2 activity by the stress sensor Keap1Principal Investigator
- Principal Investigator
  
  Suzuki Takafumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy
- Principal Investigator
  
  Yamamoto Masayuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  Tohoku University
生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用
- Principal Investigator
  
  山本雅之
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Tohoku University
Regulation of transcription factor Nrf2 activity by the stress sensor Keap1Principal Investigator
- Principal Investigator
  
  SUZUKI Takafumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
宇宙ストレス克服を目指した転写因子Nrf2の生理機能解析Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tohoku University
Stress Sensor Mechanism by the Keap1-Nrf2 SystemPrincipal Investigator
- Principal Investigator
  
  Suzuki Takafumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Mecahistic analysis of a protective response of skin tissue to UV genotoxicity
- Principal Investigator
  
  IKEHATA Hironobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tohoku University
Elucidation of redox regulatory mechanisms by transcription factor network
- Principal Investigator
  
  Itoh Ken
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Search for novel physiological function of transcriptional factor Nrf2Principal Investigator
- Principal Investigator
  
  Suzuki Takafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
ストレスセンサーKeap1のユビキチンライゲース活性制御機構の解明Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
がん微小環境における酸化ストレス防御機構の意義Principal Investigator
- Principal Investigator
  
  鈴木隆史
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Generation of disease models for neurodegenerative disorders by deleting selenoprotein synthesisPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takafumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
The missing link between proliferation and oxidative stress regulation in hematopoietic stem cells
- Principal Investigator
  
  MINEGISHI Naoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Miyagi University
  Sendai University
Physiological function analysis of stress sensor Keap1Principal Investigator
- Principal Investigator
  
  SUZUKI Takafumi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Molecular Mechanisms of Adaptive Responses to Food and Oxygen
- Principal Investigator
  
  YAMAMOTO Masayuki
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Tohoku University

[Book] 人体の細胞生物学 : カラー図解　第３章3.遺伝子発現の調節2018
- Author(s)
  鈴木隆史、山本雅之
- Total Pages
  271
- Publisher
  日本医事新報社
- ISBN
  9784784932320
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Book] 人体の細胞生物学 : カラー図解　第３章3.遺伝子発現の調節2018
- Author(s)
  鈴木隆史、山本雅之
- Total Pages
  271
- Publisher
  日本医事新報社
- ISBN
  9784784932320
- Data Source
  KAKENHI-PROJECT-17KK0183
[Book] Keap1による多様なストレス感知機構2018
- Author(s)
  鈴木隆史、山本雅之
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-26111010
[Book] 転写制御とエピジェネティクスーゲノムでコードに向けて-第V部第16章「環境応答と転写因子」2008
- Author(s)
  鈴木隆史、山本雅之
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20890013
[Book] 転写制御とエピジェネティクスーゲノムでコードに向けて-第V部第16章「環境応答と転写因子」2008
- Author(s)
  鈴木隆史, 山本雅之
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20890013
[Journal Article] Differential squamous cell fates elicited by NRF2 gain of function versus KEAP1 loss of function2024
- Author(s)
  Takahashi Jun、Suzuki Takafumi、Sato Miu、Nitta Shuji、Yaguchi Nahoko、Muta Tatsuki、Tsuchida Kouhei、Suda Hiromi、Morita Masanobu、Hamada Shin、Masamune Atsushi、Takahashi Satoru、Kamei Takashi、Yamamoto Masayuki
- Journal Title
  
  Cell Reports
  
  Volume: 43 Issue: 4 Pages: 114104-114104
- DOI
  10.1016/j.celrep.2024.114104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
[Journal Article] Effects of NRF2 polymorphisms on safety and efficacy of bardoxolone methyl: subanalysis of TSUBAKI study2023
- Author(s)
  Ikejiri Kazuaki、Suzuki Takafumi、Muto Satsuki、Takama Hirotaka、Yamawaki Kengo、Miyazawa Tatsuya、Urakawa Itaru、Aoki Yuichi、Otsuki Akihito、Katsuoka Fumiki、Kinoshita Kengo、Nangaku Masaomi、Akizawa Tadao、Yamamoto Masayuki
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 28 Issue: 3 Pages: 225-234
- DOI
  10.1007/s10157-023-02427-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
[Journal Article] Molecular Basis of the KEAP1-NRF2 Signaling Pathway2023
- Author(s)
  Suzuki Takafumi、Takahashi Jun、Yamamoto Masayuki
- Journal Title
  
  Molecules and Cells
  
  Volume: 46 Issue: 3 Pages: 133-141
- DOI
  10.14348/molcells.2023.0028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06876
[Journal Article] A Point Mutation at C151 of<i>Keap1</i>of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me)2023
- Author(s)
  Gatbonton-Schwager Tonibelle、Yagishita Yoko、Joshi Tanvi、Wakabayashi Nobunao、Srinivasan Harini、Suzuki Takafumi、Yamamoto Masayuki、Kensler Thomas W.
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 104 Issue: 2 Pages: 51-61
- DOI
  10.1124/molpharm.123.000671
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06876, KAKENHI-PROJECT-19H05649
[Journal Article] A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells2023
- Author(s)
  Baird Liam、Taguchi Keiko、Zhang Anqi、Takahashi Yushi、Suzuki Takafumi、Kensler Thomas W.、Yamamoto Masayuki
- Journal Title
  
  Redox Biology
  
  Volume: 66 Pages: 102845-102845
- DOI
  10.1016/j.redox.2023.102845
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649
[Journal Article] Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice2023
- Author(s)
  Shimizu Ritsuko、Hirano Ikuo、Hasegawa Atsushi、Suzuki Mikiko、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Uruno Akira、Suzuki Norio、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 875-875
- DOI
  10.1038/s42003-023-05251-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
[Journal Article] Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals2023
- Author(s)
  Aoki YI, Taguchi K, Anzawa H, Kawashima J, Ishida N, Otuki A, Hasegawa A, Baird L, Suzuki T, Motoike IN, Ohneda K, Kumada K, Katsuoka F, Kinoshita K, Yamamoto M.
- Journal Title
  
  J Biochem
  
  Volume: Online ahead of print. Issue: 6 Pages: 611-627
- DOI
  10.1093/jb/mvae008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
[Journal Article] Nrf2 activation improves experimental rheumatoid arthritis2023
- Author(s)
  Zhang Anqi、Suzuki Takafumi、Adachi Saki、Yoshida Eiki、Sakaguchi Shimon、Yamamoto Masayuki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 207 Pages: 279-295
- DOI
  10.1016/j.freeradbiomed.2023.07.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06876, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
[Journal Article] Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium2023
- Author(s)
  Hirose Wataru、Horiuchi Makoto、Li Donghan、Motoike Ikuko N.、Zhang Lin、Nishi Hafumi、Taniyama Yusuke、Kamei Takashi、Suzuki Mikiko、Kinoshita Kengo、Katsuoka Fumiki、Taguchi Keiko、Yamamoto Masayuki
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 15 Issue: 1 Pages: 153-178
- DOI
  10.1016/j.jcmgh.2022.09.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-21K16466, KAKENHI-PROJECT-19H05649
[Journal Article] The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation <i>In Vivo</i>2022
- Author(s)
  Kuga Ayumi、Tsuchida Kouhei、Panda Harit、Horiuchi Makoto、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Suzuki Mikiko、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 42 Issue: 7 Pages: 1-22
- DOI
  10.1128/mcb.00563-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-19H05649
[Journal Article] The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf22022
- Author(s)
  Dayalan Naidu S、Suzuki T、Dikovskaya D、Knatko EV、Higgins M、Sato M、Novak M、Villegas JA、Moore TW、Yamamoto M、Dinkova-Kostova AT.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 1 Pages: 103703-103703
- DOI
  10.1016/j.isci.2021.103703
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-19H05649
[Journal Article] Multifaceted Roles of the KEAP1-NRF2 System in Cancer and Inflammatory Disease Milieu2022
- Author(s)
  Panda Harit、Wen Huaichun、Suzuki Mikiko、Yamamoto Masayuki
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 3 Pages: 538-538
- DOI
  10.3390/antiox11030538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05649
[Journal Article] Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity2022
- Author(s)
  Panda Harit、Suzuki Mikiko、Naito Mitsuru、Saito Ritsumi、Wen Huaichun、Baird Liam、Uruno Akira、Miyata Kanjiro、Yamamoto Masayuki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 187 Pages: 92-104
- DOI
  10.1016/j.freeradbiomed.2022.05.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20K07352
[Journal Article] Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production2021
- Author(s)
  Cvetko Filip、Caldwell Stuart T.、Higgins Maureen、Suzuki Takafumi、Yamamoto Masayuki、Prag Hiran A.、Hartley Richard C.、Dinkova-Kostova Albena T.、Murphy Michael P.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100169-100169
- DOI
  10.1074/jbc.ra120.016551
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19H05649
[Journal Article] Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction2021
- Author(s)
  Zhang Anqi、Suzuki Takafumi、Adachi Saki、Naganuma Eriko、Suzuki Norio、Hosoya Tomonori、Itoh Ken、Sporn Michael B.、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 41 Issue: 11 Pages: 0023621-0023621
- DOI
  10.1128/mcb.00236-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
[Journal Article] Novel method for evaluating the health condition of mice in space through a video downlink2021
- Author(s)
  YUMOTO Akane、KOKUBO Toshiaki、IZUMI Ryutaro、SHIMOMURA Michihiko、FUNATSU Osamu、TADA Motoki N.、OTA-MURAKAMI Naoko、IINO Kayoko、SHIRAKAWA Masaki、MIZUNO Hiroyasu、KUDO Takashi、TAKAHASHI Satoru、SUZUKI Takafumi、URUNO Akira、YAMAMOTO Masayuki、SHIBA Dai
- Journal Title
  
  Exp. Anim.
  
  Volume: 70 Issue: 2 Pages: 236-244
- DOI
  10.1538/expanim.20-0102
- NAID
  130008037417
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19H05649
[Journal Article] Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice2020
- Author(s)
  Li Lei、Nakano Daisuke、Zhang Anqi、Kittikulsuth Wararat、Morisawa Norihiko、Ohsaki Hiroyuki、Suzuki Norio、Yamamoto Masayuki、Nishiyama Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 144 Issue: 4 Pages: 229-236
- DOI
  10.1016/j.jphs.2020.09.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H03191
[Journal Article] Environmental pollutants and the immune response2020
- Author(s)
  Suzuki Takafumi、Hidaka Takanori、Kumagai Yoshito、Yamamoto Masayuki
- Journal Title
  
  Nature Immunology
  
  Volume: 21 Issue: 12 Pages: 1486-1495
- DOI
  10.1038/s41590-020-0802-6
- NAID
  40022683384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K17336, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H05649
[Journal Article] Microenvironmental activation of Nrf2 restricts the progression of Nrf2-activated malignant tumors2020
- Author(s)
  Makiko Hayashi, Ayumi Kuga, Mikiko Suzuki, Harit Panda, Hiroshi Kitamura, Hozumi Motohashi, Masayuki Yamamoto
- Journal Title
  
  Cancer Research
  
  Volume: 0 Issue: 16 Pages: 00-00
- DOI
  10.1158/0008-5472.can-19-2888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J04895, KAKENHI-PROJECT-19K07379, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621
[Journal Article] Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers2020
- Author(s)
  Okazaki Keito、Anzawa Hayato、Liu Zun、Ota Nao、Kitamura Hiroshi、Onodera Yoshiaki、Alam Md. Morshedul、Matsumaru Daisuke、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5911-5911
- DOI
  10.1038/s41467-020-19593-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-19K07379, KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K16350, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08617
[Journal Article] Cellular Nrf2 levels determine cell fate during chemical carcinogenesis in esophageal epithelium2020
- Author(s)
  Horiuchi M, Taguchi K, Hirose W, Tsuchida K, Suzuki M, Taniyama Y, Kamei T, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 41 Issue: 2
- DOI
  10.1128/mcb.00536-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649
[Journal Article] Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function2019
- Author(s)
  Nagasu Hajime、Sogawa Yuji、Kidokoro Kengo、Itano Seiji、Yamamoto Toshiya、Satoh Minoru、Sasaki Tamaki、Suzuki Takafumi、Yamamoto Masayuki、Wigley W. Christian、Proksch Joel W.、Meyer Colin J.、Kashihara Naoki
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 11 Pages: 12253-12263
- DOI
  10.1096/fj.201900217r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02828, KAKENHI-PROJECT-18K19417
[Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019
- Author(s)
  Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
- Journal Title
  
  Cell Reports
  
  Volume: 28 Issue: 3 Pages: 746-758
- DOI
  10.1016/j.celrep.2019.06.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H00990, KAKENHI-PROJECT-19H01019, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17H06170, KAKENHI-ORGANIZER-15H05935
[Journal Article] Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model2019
- Author(s)
  Panda Harit、Keleku-Lukwete Nadine、Kuga Ayumi、Fuke Nobuo、Suganuma Hiroyuki、Suzuki Mikiko、Yamamoto Masayuki
- Journal Title
  
  Experimental Hematology
  
  Volume: 77 Pages: 51-60.e1
- DOI
  10.1016/j.exphem.2019.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
[Journal Article] Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation2018
- Author(s)
  Kikuchi Kenta、Iida Mayumi、Ikeda Naoki、Moriyama Shigetaka、Hamada Michito、Takahashi Satoru、Kitamura Hiroshi、Watanabe Takashi、Hasegawa Yoshinori、Hase Koji、Fukuhara Takeshi、Sato Hideyo、Kobayashi Eri H.、Suzuki Takafumi、Yamamoto Masayuki、Tanaka Masato、Asano Kenichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 201 Issue: 2 Pages: 635-651
- DOI
  10.4049/jimmunol.1800040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K15590
[Journal Article] Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.2018
- Author(s)
  Yoshida E, Suzuki T, Morita M, Taguchi K, Tsuchida K, Motohashi H, Doita M, and Yamamoto M
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 5 Pages: 386-392
- DOI
  10.1111/gtc.12579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508
[Journal Article] Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF12018
- Author(s)
  Dayalan Naidu Sharadha、Suzuki Takafumi、Yamamoto Masayuki、Fahey Jed W.、Dinkova-Kostova Albena T.
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 62 Issue: 18 Pages: 1700908-1700908
- DOI
  10.1002/mnfr.201700908
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-17K15590
[Journal Article] Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding2018
- Author(s)
  Kanamoto Mayu、Tsuchiya Yoshihiro、Nakao Yuki、Suzuki Takafumi、Motohashi Hozumi、Yamamoto Masayuki、Kamata Hideaki
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 11 Pages: e0203978-e0203978
- DOI
  10.1371/journal.pone.0203978
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16K18419, KAKENHI-PROJECT-17K15590
[Journal Article] C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape2018
- Author(s)
  Dayalan Naidu Sharadha、Muramatsu Aki、Saito Ryota、Asami Soichiro、Honda Tadashi、Hosoya Tomonori、Itoh Ken、Yamamoto Masayuki、Suzuki Takafumi、Dinkova-Kostova Albena T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8037-8037
- DOI
  10.1038/s41598-018-26269-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K15590
[Journal Article] The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.2017
- Author(s)
  Hidaka, T., Ogawa, E., Kobayashi, E.H., Suzuki, T., Funayama, R., Nagashima, T., Fujimura, T., Aiba, S., Nakayama, K., Okuyama, R., Yamamoto, M.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 18 Issue: 1 Pages: 64-73
- DOI
  10.1038/ni.3614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K10143, KAKENHI-PROJECT-17K15590, KAKENHI-PROJECT-17H04240
[Journal Article] Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.2017
- Author(s)
  Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi EH, Yamaoka A, Baird L, Takahashi N, Sato H, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 14577-14577
- DOI
  10.1038/ncomms14577
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-16K19027, KAKENHI-PROJECT-17K15590
[Journal Article] The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2017
- Author(s)
  Higashi C, Kawaji A, Tsuda N, Hayashi M, Saito R, Yagishita Y, Suzuki T, Uruno A, Nakamura M, Nakao K, Furusako S, Yamamoto M.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 802 Pages: 76-84
- DOI
  10.1016/j.ejphar.2017.02.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-16K19046, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K15590
[Journal Article] Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice.2017
- Author(s)
  Sogawa Y, Nagasu H, Iwae S, Ihoriya C, Itano S, Uchida A, Kidokoro K, Taniguchi S, Takahashi M, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Horng T and Kashihara N.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 8801-8801
- DOI
  10.1038/s41598-017-08054-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04838, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19501
[Journal Article] Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.2017
- Author(s)
  T. Suzuki, M. Yamamoto
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 41 Pages: 16817-16824
- DOI
  10.1074/jbc.r117.800169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02815
[Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.2016
- Author(s)
  Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 11624-11624
- DOI
  10.1038/ncomms11624
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228
[Journal Article] Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.2016
- Author(s)
  Iso T, Suzuki T, Baird L, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36 Issue: 24 Pages: 3100-3112
- DOI
  10.1128/mcb.00389-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-26460354
[Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016
- Author(s)
  Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
- Journal Title
  
  Nature Commun
  
  Volume: 7 Issue: 1 Pages: 12030-12030
- DOI
  10.1038/ncomms12030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
[Journal Article] Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response2016
- Author(s)
  Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M.
- Journal Title
  
  Molecular and Cellular Biology.
  
  Volume: 36 Issue: 2 Pages: 271-284
- DOI
  10.1128/mcb.00868-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815
[Journal Article] Molecular basis of the Keap1-Nrf2 system2015
- Author(s)
  T. Suzuki, M. Yamamoto
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 88 Pages: 93-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02815
[Journal Article] The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap12015
- Author(s)
  Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
- Journal Title
  
  Science Signaling.
  
  Volume: 8 Issue: 404 Pages: 404-404
- DOI
  10.1126/scisignal.aad0667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-24115007, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26650011, KAKENHI-PROJECT-26670150
[Journal Article] Molecular basis of the Keap1-Nrf2.2015
- Author(s)
  Suzuki T, Yamamoto M
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 88 Pages: 93-100
- DOI
  10.1016/j.freeradbiomed.2015.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-26111002
[Journal Article] Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.2014
- Author(s)
  Hiramoto K, Satoh H, Suzuki T, Moriguchi T, Pi J, Shimosegawa T, Yamamoto M.
- Journal Title
  
  Cancer Prevention Research
  
  Volume: 7 Issue: 8 Pages: 835-844
- DOI
  10.1158/1940-6207.capr-14-0094
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25112502, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354
[Journal Article] Keap1 inhibition attenuates glomerulosclerosis.2014
- Author(s)
  Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 29 Issue: 4 Pages: 783-791
- DOI
  10.1093/ndt/gfu002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112502, KAKENHI-PUBLICLY-25117703, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26461241
[Journal Article] Toward clinical application of the Keap1-Nrf2 pathway.2013
- Author(s)
  Suzuki T, Motohashi H, and Yamamoto M*.
- Journal Title
  
  Trends Pharmacol. Sci.
  
  Volume: 34 Issue: 6 Pages: 340-346
- DOI
  10.1016/j.tips.2013.04.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25112502
[Journal Article] Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.2013
- Author(s)
  Suzuki T, Shibata T, Takaya K, Shiraishi K, Kohno T, Kunitoh H, Tsuta K, Furuta K, Goto K, Hosoda F, Sakamoto H, Motohashi H and Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 33 Issue: 12 Pages: 2402-2412
- DOI
  10.1128/mcb.00065-13
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790340, KAKENHI-PUBLICLY-25112502
[Journal Article] Roles Nrf2 Plays in Myeloid Cells and Related Disorders.2013
- Author(s)
  Kobayashi E, Suzuki T, Yamamoto M
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2013 Pages: 529219-529219
- DOI
  10.1155/2013/529219
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25112502
[Journal Article] Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.2013
- Author(s)
  Suzuki T
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112502
[Journal Article] ユビキチンープロテアソーム系によるKeap1-Nrf2経路の制御機構2012
- Author(s)
  鈴木隆史
- Journal Title
  
  医学のあゆみ
  
  Volume: 234 Pages: 525-529
- Data Source
  KAKENHI-PUBLICLY-23112502
[Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012
- Author(s)
  Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 4 Pages: 760-766
- DOI
  10.1111/j.1349-7006.2012.02216.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24790306, KAKENHI-PLANNED-23116002
[Journal Article] Select heterozygous keap1 mutations have a dominant-negative effect on wild-type keap1 in vivo.2011
- Author(s)
  Suzuki T, Maher J, Yamamoto M.
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Pages: 1700-1709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia.2011
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M.
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 986-996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Isolation and Characterization of Renal Erythropoietin-Producing Cells from Genetically Produced Anemia Mice2011
- Author(s)
  Pan X, Suzuki N, Hirano I, Yamazaki S, Minegishi N, Yamamoto M
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 10 Pages: 25839-25839
- DOI
  10.1371/journal.pone.0025839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06108, KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002
[Journal Article] Acute erythropoietin cardioprotection is mediated by endothelial response2011
- Author(s)
  Teng R, Calvert JW, Sibmooh N, Piknova B, Suzuki N, Sun J, Martinez K, Yamamoto M, Schechter AN, Lefer DJ, Noguchi CT
- Journal Title
  
  Basic Res Cardiol
  
  Volume: 106 Issue: 3 Pages: 343-354
- DOI
  10.1007/s00395-011-0158-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Select heterozygous keap1 mutations have a dominant-negative effect on wild-type keap1 in vivo2011
- Author(s)
  Suzuki T, Maher J, Yamamoto M.
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Pages: 986-996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia2011
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M
- Journal Title
  
  Blood
  
  Volume: 117 Issue: 3 Pages: 986-996
- DOI
  10.1182/blood-2010-05-285817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216
[Journal Article] Specific contribution of the Erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stage2011
- Author(s)
  Suzuki N, Obara N, Pan X, Watanabe M, Jishage K, Minegishi N, and Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Pages: 3896-3905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011
- Author(s)
  Suzuki T, Maher JM, and Yamamoto M
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 1700-1709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Isolation and Characterization of renal erythropoietin-producing cells from genetically produced anemia mice2011
- Author(s)
  Pan X, Suzuki N, Hirano I, Yamazaki S, Minegishi N, and Yamamoto M
- Journal Title
  
  PLos One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2011
- Author(s)
  Souma T, Abe M, Moriguchi T, Yanagisawa-Miyazawa N, Shibata E, Akiyama Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: (未定)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Disrupted erythropoietin signaling promotes obesity and alters hypothalamus proopiomelanocortin production2011
- Author(s)
  Teng R, Gavrilova O, Suzuki N, Chanturiya T, Schimel D, Hugendubler L, Mammen S, Yver DR, Cushman SW, Mueller E, Yamamoto M, Hsu LL, Noguchi CT
- Journal Title
  
  Nature Commun
  
  Volume: 2 Issue: 1
- DOI
  10.1038/ncomms1526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia2011
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 986-996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Select Heterozygous Keap1 Mutations Have a Dominant-Negative Effect on Wild-Type Keap1 In Vivo2011
- Author(s)
  Suzuki T, Maher J, Yamamoto M.
- Journal Title
  
  Cancer Res
  
  Volume: 71 Issue: 5 Pages: 1700-1709
- DOI
  10.1158/0008-5472.can-10-2939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591216
[Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
- Author(s)
  Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 405 Issue: 1 Pages: 13-18
- DOI
  10.1016/j.bbrc.2010.12.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163
[Journal Article] Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages2011
- Author(s)
  Suzuki N, Obara N, Pan X, Watanabe M, Jishage K-i, Minegishi N, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 18 Pages: 3896-3905
- DOI
  10.1128/mcb.05463-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22790895
[Journal Article] Dysfunction of fibroblasts of extra-renal origin underlies renal fibrosis and renal anemia in mice2011
- Author(s)
  Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K-i, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Issue: 10 Pages: 3981-3990
- DOI
  10.1172/jci57301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591027, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22600011
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway2010
- Author(s)
  Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M, Hirohashi S
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 9095-9105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2010
- Author(s)
  Suzuki T, Maher J, Yamamoto M
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 1700-1709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
- Author(s)
  Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 30 Pages: 2668-2680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
- Author(s)
  Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 30 Issue: 12 Pages: 3016-3026
- DOI
  10.1128/mcb.01591-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591216
[Journal Article] Global downstream pathway analysis reveals a dependence of oncogenic NRF2 mutation on the mTOR growth signaling pathway2010
- Author(s)
  Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M and Hirohashi S
- Journal Title
  
  Cancer Resarch
  
  Volume: 70 Pages: 9095-9105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Fractionation of Mature Eosinophils in GATA-Reporter Transgenic Mice2010
- Author(s)
  Kim K, Suzuki N, Ohneda K, Minegishi N, Yamamoto M.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 220 Issue: 2 Pages: 127-138
- DOI
  10.1620/tjem.220.127
- NAID
  130004459794
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591216
[Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
- Author(s)
  Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 30 Pages: 3016-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher J, Suzuki T, Winnard PT, Raman V, Ebina M, Nukiwa T, Yamamoto M.
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Issue: 10 Pages: 1833-1843
- DOI
  10.1093/carcin/bgq105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591216
[Journal Article] Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway2010
- Author(s)
  Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M, Hirohashi S.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Issue: 22 Pages: 9095-9105
- DOI
  10.1158/0008-5472.can-10-0384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591216
[Journal Article] The anemia of the newborn induces erythropoietin expression in the developing mouse retina2010
- Author(s)
  Scheerer N, Dunker N, Imagawa S, Yamamoto M, Suzuki N, Fandrey J., The anemia of the newborn induces erythropoietin expression in the developing mouse retina
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
- Author(s)
  Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 30 Pages: 3016-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790268
[Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
- Author(s)
  Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.
- Journal Title
  
  Mol Cell Biol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890013
[Journal Article] Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans2009
- Author(s)
  Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, Tauchi M, Suzuki H, Hyodo I, Yamamoto M.
- Journal Title
  
  Cancer Prev.Res. 2
  
  Pages: 353-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress Th2-cytokine production or antibody production2009
- Author(s)
  Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
- Journal Title
  
  Int.Immunol 21
  
  Pages: 769-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] GATA box is essential for tissue-specific erythropoietin gene expression2008
- Author(s)
  Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, Yamamoto M. Repression via the
- Journal Title
  
  Blood 111
  
  Pages: 5223-5362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
- Author(s)
  Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M.
- Journal Title
  
  Mol Cell Biol 28
  
  Pages: 2758-2770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Repression via the GATA box is essential for tissue-specific erythropoietin gene expression2008
- Author(s)
  Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, and Yamamoto M
- Journal Title
  
  Blood
  
  Volume: 111 Pages: 5223-5362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Repression via the GATA box is essential for tissue-specific erythropoietin gene expression2008
- Author(s)
  Obara N, Suzuki N, 他
- Journal Title
  
  Blood 111
  
  Pages: 5223-5232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Physiological significance of reactive cysteine residues of Keap1 in deter mining Nrf2 activity2008
- Author(s)
  Yamamoto T, Suzuki T, 他
- Journal Title
  
  Molecular and Cellular Biology 28
  
  Pages: 2758-2770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article]2008
- Author(s)
  鈴木隆史, 他
- Journal Title
  
  「環境応答と転写因子」転写制御とエピジェネティクスーゲノムでコードに向けて(南山堂)
  
  Pages: 143-149
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
- Author(s)
  Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 28 Pages: 2758-2770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Use of gene manipulated mice in the study of erythropoietin gene expression.2007
- Author(s)
  Suzuki N, Obara N, and Yamamoto M.
- Journal Title
  
  Methods Enzymol. 435
  
  Pages: 157-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Does K-11706 enhance performance and why?2007
- Author(s)
  Imagawa S, Matsumoto K, Horie M, Ohkoshi N, Nagasawa T, Doi T, Suzuki N, and Yamamoto M.
- Journal Title
  
  Int J Sports Med. 28
  
  Pages: 928-933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Inchinkoto, an herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.2007
- Author(s)
  Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y and Suzuki H.
- Journal Title
  
  Am J Physiol Gastrointestinal Liver Physiol. 295
  
  Pages: 1450-1463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] 酸素センシングと赤血球造血シグナル2007
- Author(s)
  今川重彦、小原直、鈴木教郎、山本雅之
- Journal Title
  
  細胞 39
  
  Pages: 537-540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.2007
- Author(s)
  Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim K-C, and Engel JD.
- Journal Title
  
  Development. 139
  
  Pages: 1703-1712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] NRF2活性化型食道扁平上皮癌マウスモデルの確立とその解析2023
- Author(s)
  高橋洵、牟田達紀、佐藤美羽、矢口菜穂子、鈴木隆史、大沼忍、石田孝宣、海野倫明、亀井尚、山本雅之
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06876
[Presentation] 含セレン抗酸化酵素合成破綻状態の恒常性維持におけるKeap1過酸化水素センサーの重要性の解明2023
- Author(s)
  佐藤美羽, 矢口菜穂子, 鈴木隆史, 山本雅之
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06876
[Presentation] Nrf2 activation improves Rheumatoid arthritis of SKG mice.2022
- Author(s)
  Anqi Zhang, Saki Adachi, Eiki Yoshida, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  日本生化学会東北支部第88回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06876
[Presentation] NRF2 Activation Improves Rheumatoid Arthritis of SKG Mice.2022
- Author(s)
  Zhang Anqi、安達紗希、吉田瑛紀、鈴木隆史、山本雅之.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06876
[Presentation] Establishment of Hmox1-DsRed reporter mouse system.2020
- Author(s)
  Anqi Zhang, Saki Adachi, Tomonori Hosoya, Ken Itoh, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  第86回日本生化学会東北支部例会
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Identification of a compound which is synthetic lethal with Nrf2 activity.2019
- Author(s)
  Liam Baird, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Multiple sensor mechanism of the Keap1-Nrf2 system.2019
- Author(s)
  Takafumi Suzuki and Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Verification of the hinge & latch mechanism of Keap1-Nrf2 system by NMR method.2019
- Author(s)
  Yuta Horie, Tatsuro Iso, Jin Inoue, Takafumi Suzuki, Seizo Koshiba, Takashi Kamei, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Molecular mechanism of cellular oxidative stress sensing by Keap1.2019
- Author(s)
  Takafumi Suzuki, Aki Muramatsu, Ryota Saito, Tatsuro Iso, Saki Adachi, Hiromi Suda, Masanobu Morita, Liam Baird, Masayuki Yamamoto
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Verification of the hinge & latch mechanism of Keap1-Nrf2 system by NMR method.2019
- Author(s)
  Yuta Horie, Tatsuro Iso, Jin Inoue, Takafumi Suzuki, Seizo Koshiba, Takashi Kamei, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Verification of the hinge & latch mechanism of Keap1-Nrf2 system by NMR method.2019
- Author(s)
  Yuta Horie, Tatsuro Iso, Jin Inoue, Takafumi Suzuki, Seizo Koshiba, Takashi Kamei, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Activation of transcription factor Nrf2 suppresses autoimmune arthritis.2019
- Author(s)
  Saki Adachi, Eiki Yoshida, Eriko Naganuma, Takafumi Suzuki, Masayuki Yamamoto
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Identification of a compound which is synthetic lethal with Nrf2 activity.2019
- Author(s)
  Liam Baird, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Molecular mechanism of cellular oxidative stress sensing by Keap12019
- Author(s)
  Takafumi Suzuki, Aki Muramatsu, Ryota Saito, Tatsuro Iso, Saki Adachi, Hiromi Suda, Masanobu Morita, Liam Baird, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Multiple sensor mechanism of the Keap1-Nrf2 system.2019
- Author(s)
  Takafumi Suzuki and Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340
[Presentation] Multiple sensor mechanism of the Keap1-Nrf2 system.2019
- Author(s)
  Takafumi Suzuki and Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Identification of a compound which is synthetic lethal with Nrf2 activity.2019
- Author(s)
  Liam Baird, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Activation of transcription factor Nrf2 suppresses autoimmune arthritis.2019
- Author(s)
  Saki Adachi, Eiki Yoshida, Eriko Naganuma, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Activation of transcription factor Nrf2 suppresses autoimmune arthritis.2019
- Author(s)
  Saki Adachi, Eiki Yoshida, Eriko Naganuma, Takafumi Suzuki, Masayuki Yamamoto
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Molecular mechanism of cellular oxidative stress sensing by Keap1.2019
- Author(s)
  Takafumi Suzuki, Aki Muramatsu, Ryota Saito, Tatsuro Iso, Saki Adachi, Hiromi Suda, Masanobu Morita, Liam Baird, Masayuki Yamamoto
- Organizer
  The Environmental Response V, 17th JBS Biofrontier Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Keap1酸化ストレスセンサーの機能解析2018
- Author(s)
  村松亜紀、鈴木隆史、斎藤良太, 磯達朗、須田博美、守田匡伸、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] システイン反応性Nrf2誘導剤に対する応答を欠失したKeap1変異体の創出2018
- Author(s)
  鈴木隆史、村松亜紀、斎藤良太, 磯達朗、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Structural and functional analyses of oxidative stress response by Keap1-Nrf2 system.2018
- Author(s)
  Seizo Koshiba, Tatsuro Iso, Jin Inoue, Aki Muramatsu, Takafumi Suzuki, Takanori Kigawa and Masayuki Yamamoto.
- Organizer
  28th ICMRBS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] TBE-31はKeap1Cys151を介してNrf2を活性化し抗炎症に働く2018
- Author(s)
  村松亜紀、鈴木隆史、Dinkova-Kostova, 山本雅之
- Organizer
  第84回日本生化学会東北支部例会
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] システイン反応性Nrf2誘導剤に対する応答を欠失したKeap1変異体の創出2018
- Author(s)
  鈴木隆史、村松亜紀、斎藤良太, 磯達朗、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Keap1酸化ストレスセンサーの機能解析2018
- Author(s)
  村松亜紀、鈴木隆史、斎藤良太, 磯達朗、須田博美、守田匡伸、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Structural and functional analyses of oxidative stress response by Keap1-Nrf2 system.2018
- Author(s)
  45. Seizo Koshiba, Tatsuro Iso, Jin Inoue, Aki Muramatsu, Takafumi Suzuki, Takanori Kigawa and Masayuki Yamamoto
- Organizer
  28th ICMRBS,
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] Keap1-Nrf2系によるストレス応答メカニズムとその生理的意義2018
- Author(s)
  鈴木隆史
- Organizer
  第84回日本生化学会東北支部例会奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Keap1-Nrf2系によるストレス応答メカニズムとその生理的意義2018
- Author(s)
  鈴木隆史
- Organizer
  第84回日本生化学会東北支部例会奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] システイン反応性Nrf2誘導剤に対する応答を欠失したKeap1変異体の創出2018
- Author(s)
  鈴木隆史、村松亜紀、斎藤良太, 磯達朗、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] TBE-31はKeap1Cys151を介してNrf2を活性化し抗炎症に働く2018
- Author(s)
  村松亜紀、鈴木隆史、Dinkova-Kostova, 山本雅之
- Organizer
  第84回日本生化学会東北支部例会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Structural and functional analyses of oxidative stress response by Keap1-Nrf2 system.2018
- Author(s)
  Seizo Koshiba, Tatsuro Iso, Jin Inoue, Aki Muramatsu, Takafumi Suzuki, Takanori Kigawa and Masayuki Yamamoto.
- Organizer
  28th ICMRBS
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04963
[Presentation] Keap1-Nrf2系によるストレス応答メカニズムとその生理的意義2018
- Author(s)
  鈴木隆史
- Organizer
  第84回日本生化学会東北支部例会奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Keap1酸化ストレスセンサーの機能解析2018
- Author(s)
  村松亜紀、鈴木隆史、斎藤良太, 磯達朗、須田博美、守田匡伸、山本雅之
- Organizer
  第91回日本生化学大会
- Data Source
  KAKENHI-PROJECT-17KK0183
[Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017
- Author(s)
  鈴木隆史, 関詩織, 長沼絵理子, 高橋信行,佐藤博, 山本雅之.
- Organizer
  第40回生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Keap1-Nrf2系による酸化ストレス防御機構2017
- Author(s)
  鈴木隆史, 山本雅之
- Organizer
  第7回日本分子状水素医学生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] 酸化ストレス応答におけるKeap1の構造・相互作用解析2017
- Author(s)
  井上仁, 村松亜紀, 鈴木隆史, 磯達朗, 小柴生造, 山本雅之
- Organizer
  第56回NMR討論会
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] 酸化ストレス応答におけるKeap1の構造・相互作用解析2017
- Author(s)
  井上仁, 村松亜紀, 鈴木隆史, 磯達朗, 小柴生造, 山本雅之.
- Organizer
  第56回NMR討論会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] TBE-31はKeap1 Cys151を介してNrf2を活性化し抗炎症に働く2017
- Author(s)
  村松亜紀, 鈴木隆史, Albena Dinkova-Kostova, 山本雅之
- Organizer
  第40回生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Keap1-Nrf2システムによる酸化ストレス応答機構2017
- Author(s)
  鈴木隆史, 山本雅之
- Organizer
  第17回日本蛋白質学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017
- Author(s)
  鈴木隆史、関詩織、長沼絵里子、高橋信行、佐藤博、山本雅之
- Organizer
  第60回日本腎臓学会学術会
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Keap1-Nrf2システムによる酸化ストレス応答機構2017
- Author(s)
  鈴木隆史, 山本雅之
- Organizer
  第17回日本蛋白質学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] 骨髄球系細胞における転写因子Nrf2活性化がエラスターゼ誘導性肺気腫の形成を阻害する2017
- Author(s)
  佐藤慶, 鈴木隆史, 長沼絵理子, 杉浦久敏, 一ノ瀬正和, 山本雅之.
- Organizer
  第40回生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] Keap1-Nrf2系による酸化ストレス防御機構2017
- Author(s)
  鈴木隆史, 山本雅之
- Organizer
  第7回日本分子状水素医学生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017
- Author(s)
  鈴木隆史, 関詩織, 長沼絵理子, 高橋信行,佐藤博, 山本雅之
- Organizer
  第40回生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] Keap1-Nrf2システムによる酸化ストレス応答機構2017
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  第17回日本蛋白質学会大会
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] 骨髄球系細胞における転写因子Nrf2活性化がエラスターゼ誘導性肺気腫の形成を阻害する2017
- Author(s)
  佐藤慶, 鈴木隆史, 長沼絵理子, 杉浦久敏, 一ノ瀬正和, 山本雅之
- Organizer
  第40回生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017
- Author(s)
  鈴木隆史, 関詩織, 長沼絵里子, 高橋信行, 佐藤博, 山本雅之
- Organizer
  第60回日本腎臓学会学術会
- Data Source
  KAKENHI-PROJECT-17K15590
[Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017
- Author(s)
  鈴木隆史, 関詩織, 長沼絵里子, 高橋信行, 佐藤博, 山本雅之
- Organizer
  第60回日本腎臓学会学術会
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] Air polluteon induces Atopic dermatitiss-like pathologyes via Aryl hydrocarbon receptor2016
- Author(s)
  日高高徳、小林枝里、鈴木隆史、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Air pollution activates Aryl hydrocarbon receptor of un-differentiated keratinocytes, leading to Atopic dermatitis-like pathologiesn.2016
- Author(s)
  Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  46th Annual Meeting of the European Society for Dermatological Research. the Technical University of Munich
- Place of Presentation
  Munich (Germany)
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Nrf2活性化は骨形成低下を引き起こす2016
- Author(s)
  吉田瑛紀、鈴木隆史、長沼絵理子、小林枝里、守田匡伸、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の転写阻害2016
- Author(s)
  小林枝里、鈴木隆史、舟山亮、長嶋剛史、中山啓子、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Characterization of three major cysteine sensors of Keap1 in stress response.2016
- Author(s)
  T. Suzuki, R. Saito, K. Hiramoto, S. Asami, E. Naganuma, H. Suda, T. Iso, H. Yamamoto, M. Morita, L. Baird, Y. Furusawa, T. Negishi, M. Ichinose, M. Yamamoto
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] Air pollution activates Aryl hydrocarbon receptor in murine epidermis, leading to Atopic dermatitis-like pathologies.2016
- Author(s)
  Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, and Masayuki Yamamoto.
- Organizer
  The 41st Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Keap1の反応性システイン残基による多様なストレス感知機構2016
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] Keap1の反応性システイン残基による多様なストレス感知機構2016
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.2016
- Author(s)
  Suzuki T, Saito R, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M.
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Keap1センサーシステイン残基による多様なストレス感知機構2016
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] A novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2016
- Author(s)
  Higashi C, Hayashi M, Tsuda N, Kawaji A, Nakao K, Satoh F, Nakamura M, Furusako S, Saito R, Suzuki T, Uruno A, Yamamoto M. 
- Organizer
  32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  London (United Kingdom)
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Keap1センサーシステイン残基による多様なストレス感知機構2016
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Keap1-Nrf2系による生体防御機構2015
- Author(s)
  鈴木隆史
- Organizer
  第64回脳研･高度先進合同セミナー
- Place of Presentation
  弘前大学（青森県弘前市）
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] Keap1-Nrf2系による生体防御機構2015
- Author(s)
  鈴木隆史
- Organizer
  第64回脳研・高度先進合同セミナー
- Place of Presentation
  弘前（弘前大学医学部）
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] ストレス応答におけるNrf2, Keap1, Cul3の細胞内分子挙動の解析2015
- Author(s)
  磯達朗, 鈴木隆史, 山本雅之
- Organizer
  第81回日本生化学会東北支部例会
- Place of Presentation
  仙台（東北大学さくらホール）
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] 分子構造に基づく転写因子Nuclear factor (erythroid-derived 2)-like 2(Nrf2)の抗酸化剤応答配列認識機構の解析2015
- Author(s)
  鈴木香絵、椎名政昭、浜田恵輔、石川涼平、金井達哉、豊後泰子、岡田千佳子、馬場しほ、鈴木隆史、太田力、山本雅之、緒方一博
- Organizer
  BMB 2015
- Place of Presentation
  神戸（神戸ポートアイランド）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] ストレスセンサーKeap1のシステイン変異体ノックインマウスの機能解析2015
- Author(s)
  浅見颯一郞、斎藤良太、平本圭一郎、鈴木隆史、山本雅之
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] ストレスセンサーKeap1のシステイン変異体ノックインマウスの機能解析2015
- Author(s)
  浅見颯一郎、斎藤良太、平本圭一郎、鈴木隆史、山本雅之
- Organizer
  BMB 2015
- Place of Presentation
  神戸（神戸ポートアイランド）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015
- Author(s)
  斎藤良太、平本圭一郎、浅見颯一郞、鈴木隆史、山本雅之
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02815
[Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015
- Author(s)
  斎藤良太、平本圭一郎、浅見颯一郎、鈴木隆史、山本雅之
- Organizer
  BMB 2015
- Place of Presentation
  神戸（神戸ポートアイランド）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015
- Author(s)
  斎藤良太、平本圭一郎、浅見颯一郎、鈴木隆史、山本雅之
- Organizer
  BMB 2015
- Place of Presentation
  ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Nrf2欠損マウスにおけるアセトアミノフェン誘発性肝障害の機序検討~ミトコンドリアFusion/Fissionへ及ぼす影響~2015
- Author(s)
  森脇さや香、後藤志麻、宮脇出、出口二郎、船橋斉、鈴木隆史、山本雅之
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢（石川県音楽堂、金沢市アートホール、ホテル日航金沢）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Myeloid-specific transcription by Nrf2.2014
- Author(s)
  Eri H. Kobayashi, Takafumi Suzuki, and Masayuki Yamamoto.
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels.2014
- Author(s)
  Suzuki T, Shibata T, Takaya K, Shiraishi K, Kohno T, Hunitoh H, Tsuta K, Furuta K, Goto K, Hosoda F, Sakamoto H, Motohashi H, Yamamoto M.
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis to the lung.2014
- Author(s)
  Keiichiro Hiramoto, Hironori Satoh, Takafumi Suzuki, Takashi Moriguchi, Tooru Shimosegawa and Masayuki Yamamoto.
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] 転写因子Nrf2の遺伝子発現量の重要性2014
- Author(s)
  鈴木隆史、柴田龍弘、高屋快、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部　第80回例会
- Place of Presentation
  アキタパークホテル（秋田）
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] 転写因子Nrf2の遺伝子発現量の重要性2014
- Author(s)
  鈴木隆史、柴田龍弘、高屋快、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部　第80回例会
- Place of Presentation
  秋田、アキタパークホテル
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] ミエロイド系細胞における酸化ストレス防御機構破綻ががん転移に及ぼす影響2013
- Author(s)
  平本圭一郎、佐藤大希、鈴木隆史、山本雅之
- Organizer
  第79回日本生化学会東北支部会
- Place of Presentation
  片平さくらホール
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] 転写因子Nrf2の舌癌予防効果2013
- Author(s)
  大越明、鈴木隆史、小林俊光、山本雅之
- Organizer
  第61回日本耳鼻咽喉科学会東北地方連合学術講演会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels.2013
- Author(s)
  Takafumi Suzuki, Tatsuhiro Shibata, Kai Takaya, Hozumi Motohashi, and Masayuki Yamamoto.
- Organizer
  The 35rd NAITO conference on The Ubiquitin-Proteasome System, From Basic Mechanisms to Pathophysiological Roles
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels.2013
- Author(s)
  鈴木隆史、柴田龍弘、高屋快、本橋ほづみ、山本雅之
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Keap1-Nrf2システムによる酸化ストレス防御機構2013
- Author(s)
  鈴木隆史
- Organizer
  第31回Kidney, Hypertension & Endocrine Seminar
- Place of Presentation
  東北大学艮陵会館
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] がん微小環境における酸化ストレス防御機構の意義2012
- Author(s)
  鈴木隆史
- Organizer
  新学術領域研究「がん微小環境ネットワークの統合的研究」班会議
- Place of Presentation
  東京大学
- Year and Date
  2012-07-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112502
[Presentation] 特定のヘテロ型Keap1変異体は野性型Keap1に対してドミナントネガティブに働く2012
- Author(s)
  鈴木隆史
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23112502
[Presentation] 4NQO誘発舌がんにおけるKeap1-Nrf2系の役割2012
- Author(s)
  大越明、鈴木隆史、小林俊光、山本雅之
- Organizer
  第147回日本耳鼻咽喉科学会宮城県地方部会学術講演会
- Place of Presentation
  仙台
- Year and Date
  2012-03-18
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] トランスジェニックマウスを用いたKeap1-Nrf2システムの機能解析2012
- Author(s)
  鈴木隆史、山本雅之
- Organizer
  東北大学Network Medicine GCOE冬の合宿2012
- Place of Presentation
  秋保
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] 4NQO誘発舌がんにおけるKeap1-Nrf2系の役割2012
- Author(s)
  大越明、鈴木隆史、小林俊光、山本雅之
- Organizer
  第147回日本耳鼻咽喉科学会宮城県地方部会学術講演会
- Place of Presentation
  仙台
- Year and Date
  2012-03-18
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo.2012
- Author(s)
  鈴木隆史
- Organizer
  第78回日本生化学会東北支部例会
- Place of Presentation
  山形大学
- Invited
- Data Source
  KAKENHI-PUBLICLY-23112502
[Presentation] In vivo validation of the multiple sensing mechanism of the Keap1-Nrf2 system.2012
- Author(s)
  Takafumi Suzuki,
- Organizer
  The 33rd NAITO conference on Oxygen Biology: Hypoxia, Oxidative stress and Diseases
- Place of Presentation
  Sapporo
- Year and Date
  2012-06-26
- Data Source
  KAKENHI-PUBLICLY-23112502
[Presentation] マルチストレスセンサーKeap1の生理的機能解析2011
- Author(s)
  高屋快、鈴木隆史、山本雅之
- Organizer
  第4回リトリート大学院生研究発表会
- Place of Presentation
  東北大学・片平さくらホール
- Year and Date
  2011-01-15
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Keap1による多様なストレス感知機構の実証2011
- Author(s)
  高屋快、鈴木隆史、山本雅之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 慢性腎臓病における繊維化と腎性貧血を担う細胞の同定およびその制御法の開発2011
- Author(s)
  高瀬昌幸、浅田礼光、中村仁、小口綾貴子、浅田美咲子、鈴木教郎、山村研一、名越慈人、芝田晋介、Tata Rao Nagaswara、Hans Fehling Joerg、深津敦司、峯岸直子、北徹、木村剛、岡野栄之、山本雅之、柳田素子
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] マウス遺伝学解析に基盤とするKeap1-Nrf2システムの解明2011
- Author(s)
  山本雅之、鈴木隆史、田口恵子、本橋ほづみ
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 胎仔期神経細胞、神経堤細胞によるエリスロポエチン産生2011
- Author(s)
  平野育生, 鈴木教郎, 潘小青, 山嵜瞬, 峯岸直子, 山本雅之
- Organizer
  新学術領域「細胞運命制御」総括班主催「若手の会」
- Place of Presentation
  軽井沢
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Complementary Contribution of Nrf2 Gene Battery and Selenoproteins to Antioxidative Stress Response2011
- Author(s)
  Takafumi Suzuki
- Organizer
  Seminar of School of Biochemistry and Immunology Trinity College Dublin
- Place of Presentation
  Dublin, Ireland.
- Year and Date
  2011-01-27
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] 含セレン蛋白質とNrf2による酸化ストレス防御機構の脳発達時期における役割2011
- Author(s)
  大越明、鈴木隆史、西島維知子、山本雅之
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] 酸化ストレスによる神経疾患病態形成におけるKeap1-Nrf2系の役割の解明2011
- Author(s)
  大越明、鈴木隆史、山本雅之
- Organizer
  第4回リトリート大学院生研究発表会
- Place of Presentation
  東北大学・片平さくらホール
- Year and Date
  2011-01-15
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011
- Author(s)
  Takafumi Suzuki, Jonathan Maher, Masayuki Yamamoto
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Keap1による多様なストレス感知機構2011
- Author(s)
  高屋快、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「活性酸素シグナル」第6回班会議
- Place of Presentation
  東京
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] THE NRF2-KEAP1 STRESS RESPONSE PATHWAY : MOLECULAR BASIS OF ADAPTIVE RESPONSES AND PATHOGENESIS2011
- Author(s)
  Masayuki Yamamoto, Hirofumi Kurokawa, Takafumi Suzuki, Keiko Taguchi, Hozumi Motohashi
- Organizer
  SOT's 50th Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center in Washington, D. C.
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] マウス遺伝学解析に基盤とするKeap1-Nrf2システムの解明2011
- Author(s)
  山本雅之、鈴木隆史、田口恵子、本橋ほづみ
- Organizer
  第70回日本癌学会学術総会・名古屋国際会議場
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] エリスロポエチン欠損マウスの部分レスキューによる遺伝性超貧血マウスの樹立2011
- Author(s)
  山嵜瞬, 峯岸直子, 鈴木教郎, 山本雅之
- Organizer
  新学術領域「細胞運命制御」総括班主催「若手の会」
- Place of Presentation
  軽井沢
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 腎臓Erythropoietin産生細胞の単離と遺伝子発現様式の解析2011
- Author(s)
  潘小青、鈴木教郎、平野育生、山嵜瞬、峯岸直子、山本雅之
- Organizer
  新学術領域「細胞運命制御」総括班主催「若手の会」
- Place of Presentation
  軽井沢
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 含セレン蛋白質とNrf2による酸化ストレス防御機構の脳発達時期における役割2011
- Author(s)
  大越明、鈴木隆史、西島維知子、山本雅之
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] HIF-HRE系によるエリスロポエチン遺伝子の低酸素誘導的・組織特異的転写制御機構2011
- Author(s)
  鈴木教郎、潘小青、山本雅之
- Organizer
  第9回がんとハイポキシア研究会
- Place of Presentation
  東京
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011
- Author(s)
  Takafumi Suzuki, Jonathan Maher, Masayuki Yamamoto
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1による多様なストレス感知機構の実証2011
- Author(s)
  高屋快、鈴木隆史、山本雅之
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Keap1による多様なストレス感知機構2011
- Author(s)
  高屋快、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「活性酸素シグナル」第6回班会議
- Place of Presentation
  昭和薬科大学
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytoprotective enzymes by Nrf22010
- Author(s)
  Suzuki T, Kawatani Y, Ohkoshi A, Kelly V, Yamamoto M.
- Organizer
  9^<th> International Sympoosium on Selenium in Biology and Medicine
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 転写因子GATA2によるG1サイクリン遺伝子発現の制御2010
- Author(s)
  峯岸直子、鈴木教郎, 他
- Organizer
  BMB2010(第33回日本分子生物学会年会、第83回日本生化学会大会、合同大会)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] エリスロポエチン欠損マウスの部分レスキューによる遺伝性超貧血マウスの樹立2010
- Author(s)
  山奇瞬, 峯岸直子, 鈴木教郎, 山本雅之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Compound Deficiency of Nrf2 and Selenoproteins in hematopoietic cells leads to severe defects in erythroid and lymphoid lineage development2010
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M.
- Organizer
  9^<th> International Sympoosium on Selenium in Biology and Medicine, Selenium 2010
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Erythropoietin from neural and neural crest cells support primitive erythropoiesis2010
- Author(s)
  Hirano I, Suzuki N, Pan X, Minegishi N, Yamamoto M
- Organizer
  9th Japanese Biochemical Society Bio-frontier Symposium 2010/5th International Symposium on GATA factors
- Place of Presentation
  仙台
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 単離腎臓Erythropoietin産生細胞を用いたErythropoietin遺伝子制御機構の解明2010
- Author(s)
  平野育生、潘小青、鈴木教郎、山嵜瞬、小原直、峯岸直子、山本雅之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Cytoprotective systems of skin by selenoproteins and Nrf22010
- Author(s)
  Takayama M, Suzuki T, Takaya K, Okuyama R, Yamamoto M.
- Organizer
  9^<th> International Sympoosium on Selenium in Biology and Medicine
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 上皮細胞における転写因子Nrf2の活性化2010
- Author(s)
  田口恵子、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部会第76回例会・シンポジウム
- Place of Presentation
  福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Cytoprotective systems of skin by selenoproteins and Nrf22010
- Author(s)
  Mariko Takayama, Takafumi Suzuki, Kai Takaya, Ryuhei Okuyama, Masayuki Yamamoto
- Organizer
  9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] G1 Cyclin genes are direct target of GATA22010
- Author(s)
  Minegishi N, Suzuki N, Suzuki M, Harigae H, Yamamoto M.
- Organizer
  5th International Symposium on GATA factors
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 成獣における誘導的エリスロポエチン遺伝子破壊の造血に与える影響2010
- Author(s)
  山嵜瞬、峯岸直子、鈴木教郎、小原直、潘小青、平野育生、寺社下浩一、本田紅里穂、山本雅之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] GATA factors in tissue-specific erythropoietin gene regulation2010
- Author(s)
  Minegishi N, Suzuki, N, Obara N, Pan X, Hirano I, Yamazaki S, Yamamoto M.
- Organizer
  5th International Symposium on GATA factors
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development2010
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M
- Organizer
  9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 慢性腎臓病における線維化と腎性貧血を担う細胞の同定およびその制御法の開発2010
- Author(s)
  高瀬昌幸, 浅田礼光, 中村仁, 小口綾貴子, 浅田三咲子, 鈴木教郎, 山村研一, 名越慈人, 芝田晋介, Tata Rao Nageswara, Hans Fehling Joerg, 深津敦司, 峯岸直子, 北徹, 木村剛, 岡野栄之, 山本雅之, 柳田素子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytoprotective enzymes by Nrf22010
- Author(s)
  Takafumi Suzuki, Yukie Kawatani, Akira Okoshi, Vincent Kelly, Masayuki Yamamoto
- Organizer
  9th international Symposium on Selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] 胎仔期神経細胞,神経堤細胞によるエリスロポエチン産生2010
- Author(s)
  平野育生, 鈴木教郎, 潘小青, 山奇瞬, 峯岸直子, 山本雅之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Isolation and characterization of renal erythropoietin-producing cells : Contribution of HIF3α in vivo2010
- Author(s)
  Pan X, Suzuki N, Hirano I, Yamazaki S, Yamashita T, Ohneda O, Minegishi N, Yamamoto M.
- Organizer
  5th International Symposium on GATA factors
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Cytoprotective systems of skin by selenoproteins and Nrf22010
- Author(s)
  Mariko Takayama, Takafumi Suzuki, Kai Takaya, Ryuhei Okuyama and Masayuki Yamamoto
- Organizer
  9th international Symposium on Selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytoprotective enzymes by Nrf2.2010
- Author(s)
  Suzuki T, Kawatani Y, Okoshi A, Kelly V, Yamamoto M
- Organizer
  9th international Symposium on Selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Isolation and characterization of renal erythropoietin-producing cells : Contribution of HIF3a in vivo2010
- Author(s)
  Pan X, Suzuki N, Hirano I, Yamazaki S, Yamashita T, Ohneda O, Minegishi N, Yamamoto M
- Organizer
  9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
- Place of Presentation
  仙台
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 成獣における誘導的エリスロポエチン遺伝子破壊の造血に与える影響2010
- Author(s)
  山奇瞬, 峯岸直子, 鈴木教郎, 小原直, 潘小青, 平野育生, 寺社下浩一, 本田紅里穂, 山本雅之
- Organizer
  第33回日本分子生物学会年会,第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Hematopoietic deficiency of Nrf2 and selenoproteins leads to severe defects in erythrocytes and lymphocytes2010
- Author(s)
  Yukie Kawatani, Takafumi Suzuki, Vincent Kelly, and Masayuki Yamamoto
- Organizer
  9th international Symposium on Selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] Isolation and characterization of renal erythropoietin-producing cells : Contribution of HIF3 in vivo2010
- Author(s)
  Pan X, Suzuki N, Hirano I, Yamazaki S, Obara N, Minegishi N, Yamamoto M.
- Organizer
  52th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Erythropoietin from neural and neural crest cells support primitive erythropoiesis2010
- Author(s)
  Hirano I, Suzuki N, Pan X, Minegishi N, Yamamoto M.
- Organizer
  5th International Symposium on GATA factors
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Rescue of Epo-deficient mice from anemia by complementation with BAC transgene2010
- Author(s)
  Yamazaki S, Suzuki N, Obara N, Pan X, Hirano I, Jishage K, Honda C, Minegishi N, Yamamoto M
- Organizer
  9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
- Place of Presentation
  仙台
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Complementary contribution of Nrf2 gene battery and selenoproteins to antioxidative stress response.2010
- Author(s)
  Masayuki Yamamoto, Takafumi Suzuki, Yukie Kawatani, Vincent Kelly
- Organizer
  9th international Symposium on Selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790268
[Presentation] 単離腎臓Erythropoietin産生細胞を用いたErythropoietin遺伝子制御機構の解明2010
- Author(s)
  平野育生, 潘小青, 鈴木教郎, 山奇瞬, 小原直, 峯岸直子, 山本雅之
- Organizer
  第33回日本分子生物学会年会,第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 転写因子GATA2によるG1サイクリン遺伝子発現の制御2010
- Author(s)
  峯岸直子, 鈴木教郎, 鈴木未来子, 張替秀郎, 山本雅之
- Organizer
  第33回日本分子生物学会年会,第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytoprotective enzymes by Nrf22010
- Author(s)
  Takafumi Suzuki, Yukie Kawatani, Akira Ohkoshi, Vincent Kelly, Masayuki Yamamoto
- Organizer
  9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
- Place of Presentation
  京都
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 尿細管管腔内アルカリ化は脂肪酸結合アルブミンによる近位尿細管細胞からの活性酸素産生を、Pyk2経路を介して改善する。2009
- Author(s)
  相馬友和、阿部倫明、森口尚、秋山泰利、豊原敬文、鈴木健弘、種本雅之、阿部高明、山本雅之、伊藤貞嘉
- Organizer
  Kidney Frontier 2009
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Roles of HIF-binding sequences in chromatin dynamics during activation of the hypoxia-inducible genes2009
- Author(s)
  Norio Suzuki, Orjan Wrange, Katarina Gradin, Sergey Belikov, Kian Leong Lee, Masayuki Yamamoto, Lorenz Poellinger
- Organizer
  8th Int.Luebeck Conference Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
- Place of Presentation
  University of Luebeck, Germany
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009
- Author(s)
  鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009
- Author(s)
  鈴木隆史, 川谷幸恵, Vincent Kelly, 山本雅之
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wildtype Keap1 in vivo2009
- Author(s)
  Takafumi Suzuki, Jonathan Maher, Yukie Kawatani, Masayuki Yamamoto
- Organizer
  International symposium 2009 on Signaling Functions of Reactive Oxygen Species
- Place of Presentation
  阿蘇
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Nrf2 acts as a novel metastasis suppressor in the lung2009
- Author(s)
  Satoh H, Taguchi K, Moriguchi T, Suzuki T, Ebina M, Nukiwa T, Yamamoto M.
- Organizer
  68回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wildtype Keap1 in vivo2009
- Author(s)
  Takafumi Suzuki, Jonathan Maher, Yukie Kawatani, Masayuki Yamamoto
- Organizer
  International symposium 2009 on Signaling Functions of Reactive Oxygen Species
- Place of Presentation
  阿蘇
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009
- Author(s)
  鈴木隆史(招待)
- Organizer
  第62回日本酸化ストレス学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Nrf2-Keap1ストレス応答系は両刃の剣:発癌支持作用と化学発癌予防作用2009
- Author(s)
  山本雅之、柴田龍弘、太田力、Kit Tong、黒河博文、鈴木隆史、田口恵子、本橋ほづみ
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] Select heterogenous Keap1 mutations have a dominant-negative effect on wild type Keap1 in vivo2009
- Author(s)
  Suzuki T, Maher J, Kawatani Y, Yamamoto M.
- Organizer
  JST International Symposium on Molecular Mechanism of Environmental Response to Food and Oxyge III
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2009
- Author(s)
  Souma T, Abe M, Moriguchi T, Akiyama Y, Toyohara T, Shiwaku H, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
- Organizer
  The 1st International Symposium "Challenge to Medical Innovation"
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Compound deficiency of Nrf2 and selenoproteins in hematopoietic cells leads to severe defects in erythroid and lymphoid development2009
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M.
- Organizer
  51th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wildtype Keap1 in vivo.2009
- Author(s)
  Takahumi Suzuki
- Organizer
  International symposium 2009 on Signaling Functions of Reactive Oxygen Species
- Place of Presentation
  Kumamoto
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] エリスロポエチン遺伝子発現制御に十分な領域2009
- Author(s)
  山崎瞬, 鈴木教郎, 小原直, 潘小青, 平野育生, 峯岸直子, 山本雅之
- Organizer
  東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Nrf2-Keap1ストレス応答系は両刃の剣 : 発癌支持作用と化学発癌予防作用2009
- Author(s)
  山本雅之, 柴田龍弘, 太田力, Kit Tong, 黒河博文, 鈴木隆史, 田口恵子, 本橋ほづみ
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] 含セレン蛋白質とNrf2による酸化ストレスに対する2段階防御2009
- Author(s)
  鈴木隆史(招待)
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 含セレン蛋白質とNrf2による酸化ストレスに対する2段階防御2009
- Author(s)
  鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Localization and expression pattern of erythropoietin producing cells in the adult and developing mouse retina2009
- Author(s)
  N.Scheerer, N.Dunker, S.Imagawa, M.Yamamoto, N.Suzuki, J.
- Organizer
  8th Int.Luebeck Conference Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
- Place of Presentation
  University of Luebeck, Germany
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Rescue of Erythropoietin-Deficient Mice From Anemia by Complementation with BAC Transgene2009
- Author(s)
  Shun Yamazaki, Norio Suzuki, Naoshi Obara, Xiaoqing Pan, Ikuo Hirano, Kou-ichi Jishage, Kurisu Honda, Naoko Minegishi, Masayuki Yamamoto
- Organizer
  The 51th ASH Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 遺伝子欠失マウスのレスキューと条件付きEpo遺伝子破壊マウスの樹立2009
- Author(s)
  山奇瞬, 鈴木教郎, 小原直, 潘小青, 平野育生, 峯岸直子, 山本雅之
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] 生体におけるKeap1/Nrf2制御系の機能貢献と応答機構2009
- Author(s)
  本橋ほづみ, 藤田理恵, 鈴木隆史, Kit Tong, 黒河博文, 山本雅之
- Organizer
  第62回日本酸化ストレス学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] TGF-beta suppresses transcription of Heme Oxigenase-1 through induction of MafK and Bach12009
- Author(s)
  沖田結花里、鴨志田敦、鈴木裕之、伊東健、本橋ほづみ、五十嵐和彦、山本雅之、加藤光保
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wildtype Keap1 in vivo.2009
- Author(s)
  鈴木隆史, Jonathan Maher, Yukie Kawatani, 山本雅之
- Organizer
  International symposium 2009 on Signaling Functions of Reactive Oxygen Species
- Place of Presentation
  阿蘇
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] Rescue of erythropoietin-deficient mice from anemia by complementation with BAC transgene2009
- Author(s)
  Yamazaki, S, Suzuki N, Obara N, Pan X, Hirano I, Jishage K, Honda C, Minegishi N, Yamamoto, M.
- Organizer
  51th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Regulation of erythropoietin gene expression in mouse2009
- Author(s)
  Masayuki Yamamoto, Xiaoqing Pan, Syun Yamazaki, Ikuo Hirano, Naoko Minegishi, Norio Suzuki
- Organizer
  8th International Luebeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
- Place of Presentation
  University of Luebeck Germany
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] New function of host NRF2 in lung cancer2009
- Author(s)
  佐藤大希, 田口恵子, 森口尚, 鈴木隆史, 海老名雅仁, 貫和敏博, 山本雅之
- Organizer
  Interdisciplinary Force 学生成果発表会
- Place of Presentation
  仙台
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009
- Author(s)
  鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
- Organizer
  第62回日本酸化ストレス学会
- Place of Presentation
  福岡
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytopeotective enzymes by Nrf22009
- Author(s)
  Kawatani Y, Suzuki T, Kelly V, Yamamoto M.
- Organizer
  JST International Symposium on Molecular Mechanism of Environmental Response to Food and Oxygeniii
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Select heterogenous Keap1 mutations have a dominant-negative effect on wild type Keap1 in vivo.2009
- Author(s)
  Suzuki T, Maher J, Kawatani Y, Yamamoto M.
- Organizer
  International Symposium 2009 on Signaling Function of Reactive Oxygen Species
- Place of Presentation
  Aso
- Data Source
  KAKENHI-PROJECT-21591216
[Presentation] Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Development2009
- Author(s)
  Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M.
- Organizer
  The 51th ASH Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 遺伝子欠失マウスのレスキューと条件付きEpo遺伝子破壊マウスの樹立2009
- Author(s)
  山嵜瞬, 鈴木教郎, 小原直, 潘小青, 平野育生, 峯岸直子, 山本雅之
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1変異体によるドミナントネガティブ効果のトランスジェニックレスキュー法を用いた検証2008
- Author(s)
  鈴木隆史、Jonathan Maher、山本雅之
- Organizer
  Biochemistry and Molecular Biology 2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] Keap1変異体によるドミナントネガティブ効果のトランスジェニックレスキュー法を用いた検証2008
- Author(s)
  鈴木隆史, Jonathan Maher, 山本雅之
- Organizer
  Biochemistry and Molecular Biology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20890013
[Presentation] Keap1変異体によるドミナントネガティブ効果のトランスジェニックレスキュー法を用いた検証2008
- Author(s)
  鈴木隆史, 他
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Multiple Sensor Mechanism of the Keap1-Nrf2 System.
- Author(s)
  8.Takafumi Suzuki, Kai Takaya, Ryota Saito, Keiichiro Hiramoto, Tatsuro Iso and Masayuki Yamamoto.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research”
- Place of Presentation
  京都、国際高等研究所
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] 複合遺伝子欠失レスキュー法による転写因子Nrf2の新規生理機能探索
- Author(s)
  鈴木隆史、平本圭一郎、長沼絵理子、高橋信行、佐藤博、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] CRISPR/Cas9システムを用いたNrf2点変異マウスの作製
- Author(s)
  守田匡伸、大槻晃史、鈴木隆史、須田博美、鈴木未来子、清水律子、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Keap1 Cys273 and Cys288 are functional sensors for 15d-PGJ2 to activate Nrf2 signaling.
- Author(s)
  9.Takafumi Suzuki, Ryota Saito, Kei-ichiro Hiramoto, Tatsuro Iso, Masayuki Yamamoto.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Robinson College, Cambridge, UK
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Keap1 Cys273 and Cys288 are functional sensors for 15d-PGJ2 to activate Nrf2 signaling.
- Author(s)
  Takafumi Suzuki, Ryota Saito, Kei-ichiro Hiramoto, Tatsuro Iso, Masayuki Yamamoto.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease.
- Place of Presentation
  Robinson College, Cambridge, UK.
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] 複合遺伝子欠失レスキュー法による転写因子Nrf2の新規生理機能探索
- Author(s)
  鈴木隆史、平本圭一郎、長沼絵理子、高橋信行、佐藤博、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] Myeloid-specific transcriptional regulation by Nrf2.
- Author(s)
  Eri H. Kobayashi, Takafumi Suzuki, Masayuki Yamamoto.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease.
- Place of Presentation
  Robinson College, Cambridge, UK.
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Keap1 Cys273 and Cys288 are functional sensors for 15d-PGJ2 to activate Nrf2 signaling.
- Author(s)
  Suzuki T, Saito R, Hiramoto K, Iso T, Yamamoto M.
- Organizer
  The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Cambridge, UK.
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] ストレス応答型転写因子Nrf2による炎症性サイトカイン遺伝子の発現抑制
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
- Organizer
  修飾シグナル病若手ワークショップ
- Place of Presentation
  森秋旅館（湯河原町）
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] Multiple Sensor Mechanism of the Keap1-Nrf2 System.
- Author(s)
  Takafumi Suzuki, Kai Takaya, Ryota Saito, Keiichiro Hiramoto, Tatsuro Iso and Masayuki Yamamoto.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research”
- Place of Presentation
  国際高等研究所（京都）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PUBLICLY-25112502
[Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の発現抑制
- Author(s)
  小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460354
[Presentation] CRISPR/Cas9システムを用いたNrf2点変異マウスの作製
- Author(s)
  守田匡伸、大槻晃史、鈴木隆史、須田博美、鈴木未来子、清水律子、山本雅之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460354
[]
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[]

1. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 6 results

# of Collaborated Products: 128 results
2. TAGUCHI Keiko (20466527)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. MINEGISHI Naoko (40271895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
4. MORITA Masanobu (10519094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KATSUOKA Fumiki (30447255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MOTOHASHI Hozumi (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
7. KUROKAWA Hirofumi (80359546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Norio (20447254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 73 results
9. MORIGUCHI Takashi (10447253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. Itoh Ken (10323289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Nobuyuki (40588456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. SATO Hiroshi (60215829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. IKEHATA Hironobu (90250737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Yamauchi Masanori (00404723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 濱崎純 (80533588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 杉野繁一 (00423765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡部聡 (50432357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 木下賢吾 (60332293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SEKI Shiori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HIRAMOTO Keiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. NAGANUMA Eriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. ISO Tatsuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. MURAMATSU Aki

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
24. SAITO Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SUDA Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. BAIRD Liam

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SUZUKI Mikiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. SEKINE Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 佐藤英世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 舟山亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 松丸大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 宮崎陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 石田典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Takafumi 鈴木 隆史

SUZUKI Takafumi 鈴木 隆史

Research Projects

Research Products

Co-Researchers

KEAP1-NRF2制御系による多様な環境ストレス感知機構の分子基盤解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

宇宙環境ストレス応答の理解から挑む加齢性疾患の克服Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Keap1-Nrf2制御系によるストレス応答の動的構造基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Adverse Events-free Local Anesthetics in Cryo-EM Structural Determination of Sodium Channels

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of transcription factor Nrf2 activity by the stress sensor Keap1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of transcription factor Nrf2 activity by the stress sensor Keap1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

宇宙ストレス克服を目指した転写因子Nrf2の生理機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Stress Sensor Mechanism by the Keap1-Nrf2 SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mecahistic analysis of a protective response of skin tissue to UV genotoxicity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of redox regulatory mechanisms by transcription factor network

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for novel physiological function of transcriptional factor Nrf2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Suzuki Takafumi 鈴木隆史

SUZUKI Takafumi 鈴木隆史

[Book] 人体の細胞生物学 : カラー図解　第３章3.遺伝子発現の調節2018

[Book] 人体の細胞生物学 : カラー図解　第３章3.遺伝子発現の調節2018