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Katsura Yoshimoto  桂 義元

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… Alternative Names

KATSURA Yoshimoto  桂 義元

YOSHIMOTO Katsura  桂 義元

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Researcher Number 90027095
Affiliation (Current) 2025: 日本大学, 医学部, その他
Affiliation (based on the past Project Information) *help 2008: Nihon University, 医学部, 兼任講師
2007: Nihon University, 医学部, 客員教授
2005 – 2006: 東京医科歯科大学, 難治疾患研究所免疫疾患部門, 非常勤講師(客員教授)
2002: 東京医科歯科大学, 大学院・医歯学総合研究科, 客員教授
2000 – 2001: 京都大学, 再生医学研究所, 教授 … More
1998 – 2001: 京都大学, 再生医科学研究所, 教授
1999: Institute for Frontier Medical Science Professor, 再生医科研究所, 教授
1999: 京都大学, 大学院・再生医科学研究所, 教授
1993 – 1997: 京都大学, 胸部疾患研究所, 教授
1996: 京都大学, 胸腺疾患研究所, 教授
1990 – 1992: 京都大学, 医学部, 教授
1988 – 1991: 京都大学, 胸部疾患研究所, 教授
1990: 京都大学, 胸部疾患研, 教授
1990: Kyoto Univ., Chest Dis. Res. Inst., Professor, 胸部疾患研究所
1989: 京都大学, 胸部研, 教授
1987: Chest Disease Research Institute, Kyoto University. Ptoseddor, 結核胸部疾患研究所, 教授
1986: Chest Disease Research Institute, Kyoto University. Professor, 結核胸部疾患研究所, 教授 Less
Review Section/Research Field
Principal Investigator
Immunology / Laboratory animal science / 医学一般 / Immunology / Biological Sciences
Except Principal Investigator
Immunology / Biological Sciences
Keywords
Principal Investigator
T細胞 / 分化 / 胸腺 / T cell / differentiation / thymus / 前駆細胞 / 造血幹細胞 / AIDS / progenitor … More / hematopoietic stem cell / 決定 / T cell progenitor / 細胞間相互作用 / ストローマ細胞 / 転写因子 / T前駆細胞 / 遺伝子治療 / 幹細胞 / 骨髄 / 遺伝子導入 / Thymus / 正・負の選択 / Antisense RNA / Transgenic mouse / Gene therapy / Human immunodeficiency virus / CD4 gene / Model animal / アンチセンスRNA / トランスジェニックマウス / CD4遺伝子 / モデル動物 / Gene / Electric pulse / Electroportion / 電気的遺伝子移入 / 電気的細胞融合 / 電気的膜穿孔 / 遺伝子移入 / DNA / 遺伝子 / 高電圧パルス / 電気穿孔 / Differentiation / Hemopoietic stem cell / 血液幹細胞 / NK cell / NK細胞 / cell-to-cell interaction / microenvironment / epithelial cell / 微小環境 / 上皮細胞 / lineage committed progenitor / AGM region / commitment / ミエロイド細胞 / B細胞 / 系列特異的前駆細胞 / AGM領域 / コミットメント / positive selection / stromal cell / transcription factor / 増殖因子 / 胸腺ストローマ細胞 / 生長因子 / 正の選択 / Organ culture / Stromal cell / Transcription factor / Adhesion molecule / Stem cell / モノクローナル抗体 / 臓器培養 / 接着分子 / gene therapy / stem cell / bone marrow / retrovirus vector / エイズ / レトロウイルスベクタ- / Cytokine / Stroma cells / Development / サイトカイン / ストロ-マ細胞 / γδT細胞 / 遺伝子再構成 / 胸線 / γσT細胞 / αβT細胞 / 移出 / ケモカインレセプター / ケモカイン / 系列決定 … More
Except Principal Investigator
トランスジェニックマウス / 重点領域研究 / 免疫系 / 神経・内分泌系 / サイトカイン / シグナル伝達 / 胚中心 / stem cell factor / 血液幹細胞 / 生体高次調節 / costimulatory factor / apoptosis / cytokine / antigen receptor / tolerance / signal transduction / lymphocyte lineage / クローナル除去 / リンパ球初期分化 / 補助因子受容体 / サイトカイン受容体 / 骨髄ストローマ / 補助刺激因子 / 細胞死 / 抗原受容体 / 免疫寛容 / リンパ球増殖分化 / 間葉系細胞株 / 組織培養 / 胸腺 / DLL1遺伝子 / 系列決定 / γδT細胞 / αβT細胞 / CD94 / NK細胞 / STAT / BLNK / Btk / プレB細胞レセプター / 遺伝子再構成 / リンパ球前駆細胞 / T細胞分化 / B細胞分化 / 胸腺外分化 / Bリンパ球 / Tリンパ球 / コミットメント / GTPase活性化蛋白 / クローン増巾 / アナ-ジ- / 免疫応答 / 細胞骨格 / 細胞接着 / Ras / Rap1 / 低分子G蛋白 / 遺伝子組み換え / 転写因子 / 細胞分化 / インテグリン / 低分子量G蛋白 / レパートリー形成 / 抗原レセプター / インターロイキン11 / トランスフェリンレセプター / ストロマ細胞 / P53遺伝子 / 受容体型チロシンキナーゼ / インタ-ロイキン11 / 胸腺ストロ-マ細胞 / M‐CSFレセプタ- / p53遺伝子 / c‐kit / T細胞 / 巨核球コロニ- / GーCSFレセプタ- / gp55遺伝子 / 細胞周期 / CD34 / 造血幹細胞 Less
  • Research Projects

    (22 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (38 People)
  •  Identification of prethymic T cell progenitors in adult micePrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Nihon University
  •  αβT細胞系列とγδT細胞系列への運命決定の分子機構の解明

    • Principal Investigator
      河本 宏
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  免疫システム構築の情報伝達制御

    • Principal Investigator
      烏山 一
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  リンパ球の系列分岐・運命分岐を決定するシグナル伝達機構Principal Investigator

    • Principal Investigator
      桂 義元
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
      Kyoto University
  •  レパートリー形成の分子機構

    • Principal Investigator
      湊 長博
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  Elucidation of the mechanism of lineage commitment and differentiation in T cell developmentPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Cell-to-Cell Interaction in T Cell DifferentiationPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Determination and differentiation of heamtopoietic stem cell toward T, B and myeloid cell lineagesPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Studies on the mechanism of T cell development in the thymusPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Clarification of the role of cells constructing the thymic microenvironment in the early T cell developmentPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular mechnisms of immune tolerance.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  免疫系と神経・内分泌系との相互制御機構

    • Principal Investigator
      村松 繁
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析ー

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  神経・内分泌系と連携する免疫系による生体の高次調節

    • Principal Investigator
      村松 繁
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析

    • Principal Investigator
      溝口 秀昭
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  Establishment of a high efficiency method for gene transfer into the hematopoietic stem cellPrincipal Investigator

    • Principal Investigator
      KATSURA Yoshimto
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kyoto University
  •  神経・内分泌系と連携する免疫系による生体の総合調節

    • Principal Investigator
      村松 繁
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Analysis of the Mechanism of Induction of T cell development in the Thymus.Principal Investigator

    • Principal Investigator
      YOSHIMOTO Katsura
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Human CD4 gene transgenic mouse as an AIDS model animal.Principal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Laboratory animal science
    • Research Institution
      KYOTO UNIVERSITY
  •  Studies on the differentiation of T cells from hemopoietic stem cell.Principal Investigator

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Impoved electroporation system for high-vield gene transfer into mammalian cells.Principal Investigator

    • Principal Investigator
      KATSRA Yoshimoto
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      医学一般
    • Research Institution
      Kyoto University

All 2008 2007 2005

All Journal Article Presentation

  • [Journal Article] T前駆細胞の発生2008

    • Author(s)
      河本 宏, 桂 義元
    • Journal Title

      メディカルバイオ 5

      Pages: 32-38

    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] Adult T-cell progenitors retain myeloidpotential2008

    • Author(s)
      Wada H,Masuda K,Satoh R, Kakugawa K, Ikawa T, Katsura Y, Kawamoto H
    • Journal Title

      Nature 452

      Pages: 768-772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] T前駆細胞の発生:T細胞系列のアイデンティティー2008

    • Author(s)
      河本宏、桂義元
    • Journal Title

      メディカルバイオ 5

      Pages: 32-38

    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] Quantification of progenitors capable of generating T cells in humancord blood.2007

    • Author(s)
      Kato M, Masuda K, Kakugawa K, Kawamoto H, Mugishima H, Katsura Y
    • Journal Title

      European Journal of Haematology 80(2)

      Pages: 151-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] Quantification of Progenitors capable of generating T cell In human cord blood2007

    • Author(s)
      Kato M, Masuda K, Kakugawa K, Kawamoto H, Mugishima H, Katsura Y
    • Journal Title

      European Journal of Haematology 80(2)

      Pages: 151-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] T cell lineage determination precedes the initiation of TCRbeta gene rearrangement2007

    • Author(s)
      Masuda K,Kakugawa K,Nakayama T,Minato M,Katsura Y,Kawamoto H
    • Journal Title

      Journal of Haematology 179

      Pages: 3699-3706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] T cell lineage determination precedes the initiation of TCRbeta gene rearrengement.2007

    • Author(s)
      Masuda K, Kakugawa K, Nakayama T, Minato M, Katsura Y, Kawamoto H
    • Journal Title

      Journal of Immunology 179

      Pages: 3699-3706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Journal Article] Thymic anlage is colonized by progenitors restricted to T, NK and dendritic cell lineages.2005

    • Author(s)
      Masuda, K., Itoi, M., Amagai, T., Minato, N., Katsura, Y., Kawamoto, H.
    • Journal Title

      J.Immunol. 174

      Pages: 2525-2532

    • Data Source
      KAKENHI-PROJECT-17047043
  • [Journal Article] The earliest thymic progenitors in adults are restricted to T, NK and dendritic cell lineages and have a potential to form more diverse TCR-□ chains than fetal progenitors.2005

    • Author(s)
      Lu, M., R.Tayu, T.Ikawa, K.Masuda, I.Matsumoto, H.Mugishima, H.Kawamoto, Y.Katsura.
    • Journal Title

      J.Immunol. 175

      Pages: 5848-5956

    • Data Source
      KAKENHI-PROJECT-17047043
  • [Journal Article] Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.2005

    • Author(s)
      Masuda, K., H.Kubagawa, T.Ikawa, C.C.Chen, K.Kakugawa, M.Hattori, R.Kageyama, M.D.Cooper, N.Minato, Y.Katsura, H.Kawamoto.
    • Journal Title

      EMBO J 24

      Pages: 4052-4060

    • Data Source
      KAKENHI-PROJECT-17047043
  • [Presentation] 胸腺皮質の修復再生機構2007

    • Author(s)
      佐藤瑠美、桂義元、Ewijk W.v.、河本宏
    • Organizer
      第17回Kyoto cell Conference (第17回KTCC事務局)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Presentation] Thymic cortical epithelial cell are generated in two separate waves.2007

    • Author(s)
      佐藤 瑠美, 桂 義元,
    • Organizer
      第17回Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19590500
  • [Presentation] Thymic cortical epithelial cells are generated in two separate waves2007

    • Author(s)
      佐藤留美、桂義元、Ewijk W.v.、河本宏
    • Organizer
      第37回日本免疫学会総会・学術集会(特定非営利活動法人 日本免疫学会)
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590500
  • 1.  FUJIMOTO Shinji (60199370)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  HIROKAWA Katsuiku (00014093)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  SAITO Takashi (50205655)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  NISHIKAWA Shin-ichi (60127115)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  村松 繁 (30025291)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  名取 俊二 (50012662)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  溝口 秀昭 (70049021)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  中畑 龍俊 (20110744)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  浅野 茂隆 (50134614)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  須田 年生 (60118453)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  平嶋 邦猛 (00165169)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SAKAGUCHI Nobuo (70192086)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  KINA Tatsuo (30127071)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  岡田 秀親 (30160683)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  熊谷 勝男 (00005018)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  高浜 洋介 (20183858)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  烏山 一 (60195013)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  徳久 剛史 (20134364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  TESHIGAWARA Keisuke (50217402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HIRANO Toshio (40136718)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SUZUKI Gen (00179201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HABU Sonoko (30051618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OKADA Yasunobu (10025661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ISOBE Ken-ichi (20151441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  中埜 幸治 (00137134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  藤沢 肇 (60079689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  湊 長博 (40137716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  谷口 克 (80110310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  河本 宏 (00343228)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 32.  上出 利光 (00160185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  佐竹 正延 (50178688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  中内 啓光 (40175485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  日合 弘 (10073131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  TAMURA Masahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  GERMERAAD Wi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  VAN Ewijk Wi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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