KIMURA Mikio 木村幹男

Researcher Number	90114462
External Links
Affiliation (based on the past Project Information) *help	2004 – 2005: 国立感染症研究所, 感染症情報センター, 室長 2001: National Institute of Infections Diseases, Sinior Research Scientist, 感染症情報センター, 室長(研究職) 2000 – 2001: National Institute of Infectious Diseases, Infectious Diseases Surveillance Center, Section Chief., 感染症情報センター, 室長 2000: 国立感染症研究所, 室長(研究職) 1999: 東京大学, 医科学研究所, 助手 1990 – 1997: 東京大学, 医科学研究所, 助手 1986 – 1987: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator 内科学一般 Except Principal Investigator Experimental pathology / Biological pharmacy / Drug development chemistry / 応用薬理学・医療系薬学 / 寄生虫学(含医用動物学) / Laboratory medicine
Keywords	Principal Investigator 自己免疫 / lpr^<cg> gene / 自己免疫病 / gp120 / HIV / gld / lpr / superantigen / mouse mammary tumor virus / MRL mouse … More / glomerlonehritis / autoimmune disease / VB8.2 / レトロウイルス / スーパー抗原 / マウス乳癌ウイルス / MRLマウス / lpr^<cg>遺伝子 / 糸球体腎炎 / idiotype network / autoimmunity / 抗gp120抗体 / 自己免疫マウス / イディオタイプネットワーク / 1pr^<cg>遺伝子 / PCR法 / 抗原検出法 / 再燃 / 熱帯熱マラリア / ホーミング / DN細胞 / ヘテロ接合 / lprcg / 転移 / 浸潤 / リンパ節腫脹 / lpr^<cg> … More Except Principal Investigator 自己免疫病 / マラリア / lpr^<cg>遺伝子 / malaria / リンパ節腫脹 / lpr^<cg> gene / gld遺伝子 / RT-PCR / Microtiter plate-hybridization / PCR / MRL mice / 相補作用 / MRLマウス / Lymphadenopathy / Autoimmune disease / マウス / hormone-dependent mammary tumor / autoimmune disease / lens / hereditary cataract / early development / kidney / mice / type IV collagen / Basement membrane / コンパクション / マウス初期発生 / マウス腎臓 / 【IV】型コラーゲン / 転移 / 自律性獲得 / 進展 / ホルモン依存性乳癌 / 水晶体 / 遺伝性白内障 / 初期発生 / 腎臓 / IV型コラーゲン / 基底膜 / mechanism analysis / johzan alkaloid / antimalarials / drug-resistant / endoperoxides / 薬剤耐性メカニズム / 天然生薬抗マラリア資源 / 作用機序解析 / 耐性機構 / 薬剤耐性 / 環状過酸化化合物 / 新規抗マラリア薬 / therapeutic effect / β-1, 3-D-glucan inhibitor / Pneumocystis pneumonia / 新規のリカニ肺炎治療薬 / リポペプチド化合物 / 治療効果 / リポペプタイド化合物 / 新規のカリニ肺炎治療薬 / Japanese patients / mefloquine / severe malaria / pharmacokinetics / antimalarial drugs / falcipalum malaria / HPLC / 日本人症例 / 適正化 / 薬物動態 / 治療 / メフロキン / 抗マラリア薬 / 重症熱帯熱マラリア / Loop-mediated Isothermal Amplification / Plasmodium falciparum / LAMP method / Diagnosis of DNA / Malaria / 多型 / 18S rRNA / 卵形マラリア / 四日熱マラリア / 三日熱マラリア / 熱帯熱マラリア / 遺伝子 / 薬剤耐性マラリア / 等温遺伝子増幅法 / 熱帯熱マラリア原虫 / LAMP法 / DNA診断 / Diagnosis / 診断法 / Gene therapy / Lymphoproliferation / Vbeta8.2+ T cells / Mammary tumor virus / Superantigen / 1pr^<cg>遺伝子 / 遺伝子治療 / Vβ8.2T細胞 / マウス乳癌ウイルス / スーパー抗原 / imported malaria / Plasmodium ovale / 18S rRNA gene / DNA diagnosis / malaria parasite / 卵型 / 三日熱 / 熱帯熱 / 原虫 / リボソーム / 診断 / DNA / 18S rRNA遺伝子 / 輸入マラリア / 卵形マラリア原虫 / 18SrRNA遺伝子 / DNA診断法 / マラリア原虫 / lymphadenopathy / artiritis / gromeluronephritis / congenic / autoimmunity / MRL background / mouse model / リンパ筋腫脹 / 血管炎 / 糸球体腎炎 / コンジェニック / MRL背景 / マウスモデル / Homing / Complementation / Nephritis / Autoimmunity / Gld gene / Lpr^<cg> gene / 全身性リンパ節腫脹 / ホーミング / 腎炎 / 自己免疫 / Autoantibody / Thymus / gld gene / Double-negative T cells / Mouse / ホ-ミング / 異常T細胞 / 自己抗体 / 胸腺 / CD4^ー8^ーT細胞 / 全身リンパ節腫脹 Less

New antiamlarial drug development research against drug-resistant Plasmodium falciparum
- Principal Investigator
  
  KIM Hyesook
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  OKAYAMA UNIVERSITY
Therapeutic effect of a water-soluble echinocandin on Pneumo cystis Pneumonia
- Principal Investigator
  
  FURUTA Takahisa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The University of Tokyo
熱帯熱マラリア治療の適正な評価に関する研究Principal Investigator
- Principal Investigator
  
  木村幹男
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Development of simple and specific DNA diagnostic method of Malaria in Malaria endemic areas
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
Pharmacokinetic study on the establishment of appropriate therapy of Japanese severe malaria patients
- Principal Investigator
  
  OHTOMO Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Jikei University School of Medicine
Amelioration of lpr^<cg>-induced autoimmune diseases with Vbeta8.2-specific viral superantigen and its application to gene therapy in mice
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Diagnosis of malaria by RT-PCR
- Principal Investigator
  
  FURUTA Takahisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokyo
Development of a new DNA diagnostic system for the species-specific detection of human malaria parasites using specific nucleotide sequences of the 18S ribosomal RNA gene.
- Principal Investigator
  
  WATAYA Yusuke
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Analysis and murine atoimmune disease utilizing a superantigen possessed by a retrovirus.Principal Investigator
- Principal Investigator
  
  KIMURA Mikio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Elucidation of properties and mechanism of development of autoimmune diseases in new congenic MRL/MpJ-lprcg/lprcg mice
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Role of anti-HIV-gp120 antibody in the lpr^<cg> and other autoimmune mice.Principal Investigator
- Principal Investigator
  
  KIMURA Mikio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
lprcg、lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明Principal Investigator
- Principal Investigator
  
  木村幹男
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Studies on background genes aggravating lpr^<cg>-induced nephritis and complementation between lpr^<cg> and gld genes
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
lpr^<cg>,lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明Principal Investigator
- Principal Investigator
  
  木村幹男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Studies on the Mechanism of Induction of Autoimmune Disease by the Novel Lymphoproliferation gene, lpr^<cg>
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Institute of Medical Science, University of Tokyo
Studies on the roles of collagens in cell proliferation and differentiation, tissue organization, and pathological changes
- Principal Investigator
  
  MATSUZAW akio
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Institute of Medical Science, University of Tokyo

All 2004

All Book

[Book] 抗原虫薬2004
- Author(s)
  金恵淑, 綿矢有佑, 木村幹男, 益山新樹, 野島正朋
- Total Pages
  5
- Publisher
  臨床と微生物
- Data Source
  KAKENHI-PROJECT-16390031
[Book] 抗原虫薬2004
- Author(s)
  金惠淑, 綿矢有佑, 木村幹男, 益山新樹, 野島正朋
- Total Pages
  5
- Publisher
  臨床と微生物
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390031

1. MATSUZAWA Akio (50012745)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. KATAGIRI Takuya (70126100)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. FURUTA Takahisa (30143514)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. WATAYA Yusuke (90127598)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. KIM Hye-sook (70314664)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. WATANABE Tomomasa (10100174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. IKEDA Hidetoshi (60101119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NARIUCHI Hideo (10012741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. WAKABAYASHI Tomo (90092379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ARAI Meiji (30294432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NEGISHI Kazuo (70116490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHTOMO Hiroshi (80072916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. WATANABE Naohiro (00057019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAWAI Satoru (70275733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TANAKA Shin (70134624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松岡裕之 (10173816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 早津彦哉 (10012593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMANE Akio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIMURA Mikio 木村 幹男

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Analysis and murine atoimmune disease utilizing a superantigen possessed by a retrovirus.Principal Investigator

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Role of anti-HIV-gp120 antibody in the lpr^<cg> and other autoimmune mice.Principal Investigator

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lprcg、lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明Principal Investigator

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lpr^<cg>,lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明Principal Investigator

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KIMURA Mikio 木村幹男