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KITA Kiyoshi  北 潔

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Kita Kiyoshi  北 潔

KITA Kiyosi  北 潔

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Researcher Number 90134444
Other IDs
External Links
Affiliation (Current) 2025: 長崎大学, 熱帯医学・グローバルヘルス研究科, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 長崎大学, 熱帯医学・グローバルヘルス研究科, 教授
2019 – 2021: 長崎大学, 熱帯医学・グローバルヘルス研究科, 教授
2017: 東京大学, 大学院医学系研究科
2016 – 2017: 長崎大学, 熱帯医学・グローバルヘルス研究科, 教授
2016: 長崎大学, 熱帯医学グローバルヘルス研究科, 教授 … More
2014 – 2016: 東京大学, 医学(系)研究科(研究院), 教授
2015: 東京大学, 大学院医学系研究科, 教授
2015: 長崎大学, グローバルヘルス研究科, 教授
2007 – 2010: The University of Tokyo, Graduate School of Medicine, Professor
2006: 東大, 医学(系)研究科(研究院), 教授
2005 – 2006: 東京大学, 医学系研究科, 教授
2005 – 2006: The University of Tokyo, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授
1998 – 2005: 東京大学, 大学院・医学系研究科, 教授
1999 – 2001: 東京大学, 医学系研究科, 教授
1999 – 2000: 東京大学, 医学部, 教授
1998: 東京大学, 医学研究科, 教授
1997: 医科学研究所, 助教授
1991 – 1997: 東京大学, 医科学研究所, 助教授
1992: 東京大学, 医科研, 助教授
1989 – 1990: 順天堂大学, 医学部, 講師
1989: 順天堂大学, 医学部・寄生虫学教室, 講師
1987: Juntendo University School of Medicine, 医学部・寄生虫学講座, 助手
1987: Juntendo University School of Medicine, 医学部・寄生虫学講座, 講師
1986: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
寄生虫学(含医用動物学) / Biological Sciences / Basic Section 49040:Parasitology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 49010:Pathological biochemistry-related / General medical chemistry / Parasitology (including sanitary zoology) / Parasitology (including Sanitary zoology)
Except Principal Investigator
寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology) … More / 寄生虫学(含医用動物学) / Bioproduction chemistry/Bioorganic chemistry / Biological Sciences / Functional biochemistry / Biological Sciences / Infectious disease medicine / Tumor biology / Area studies / Veterinary medical science / Virology Less
Keywords
Principal Investigator
ミトコンドリア / 複合体II / 低酸素適応 / フマル酸還元酵素 / 呼吸鎖 / mitochondria / Ascaris suum / コハク酸脱水素酵素 / 薬剤開発 / マラリア … More / Malaria / complex II / アスコフラノン / トリパノソーマ / シアン耐性酸化酵素 / 寄生虫 / 進化 / 寄生適応 / 感染症 / NADH-フマル酸還元系 / ロドキノン / 回虫 / 大腸菌 / アセンブリー / シトクロムb / ケミカルバイオロジー / 化合物探索 / 構造生物学的解析 / 生化学的解析 / エネルギー転換 / 硫化水素代謝 / マンソン住血吸虫 / ウガンダ / オンコセルカ感染 / 興奮性アミノ酸 / うなづき症候群 / 代謝経路 / 代謝 / 代替経路 / 酸化的リン酸化 / ミトコンドリア病 / asucofuranone / cyanide-resistant oxidase / Trypanosome / percoll / cell fractionation / apicoplast / Mitochondria / 構造活性相関 / GFP / パーコール / 細胞分画 / アピコプラスト / biosynthesis of ubiquinone / adaptation to low oxygen tension / crystal structure analysis / parasite / NADH-fumarate reductase / HIF-1 / NADH-フアル酸還元系 / ユビキノン生合成 / 結晶解析 / enzyme evolution / oxygen adaptation / quinol-fumarate reductase / Complex II / 回虫(Ascaris suum) / 酵素進化 / キノールーフアル酸還元酵素 / 回虫(Assaris suum) / vector / animal model / immunoresponse / drug developmen / vaccine / Parasitic adaptation / Tropical infectious diseases / ベクター / 実験動物モデル / 免疫応答 / 新薬開発 / 熱帯感染症 / 宿主・寄生体相互作用 / 新興・再興感染症 / 化学療法剤 / ワクチン / respiratory chain / isozyme / fumarate reductase / succinate dehydrogenase / adaptative evolution / gene expression / 回虫(Ascans suum) / アイソザイム / 呼吸鎖電子伝達系 / 回虫(Ascarrs suum) / 適応進化 / 遺伝子発現 / cDNA sequence / cloning / cytochrome b / サブユニットの解離 / cDNA塩基配列 / クロ-ニング / シアン耐酸化酵素 / 生合成 / 微生物 / 特殊環境 / 細胞・組織 / エネルギー代謝 / オルガネラ / 発生・分化 / 発現制御 / 酵素 / フマル酸呼吸 / 酸素適応 / 立体構造解析 / 結晶化 / 複合体I / コハク酸脱水酵素 / ヘム鉄 / ヘムb / 酸化還元酵素 / ヘムタンパク質 … More
Except Principal Investigator
ミトコンドリア / 寄生虫 / マラリア / 熱帯熱マラリア / 微生物 / 細菌 / ウイルス / 免疫 / ワクチン / affinity labeling / Crithidia fasciculata / SERA / mitochondria / Trichinella britovi / Caenorhabditis elegans / tRNA / Molecular epidemiology / International collaboration / 遺伝子解析 / 分子疫学的調査 / 国際研究者交流 / アセトゲニン / 呼吸鎖阻害剤 / G6PD deficiency / 新型四日熱マラリア原虫 / G6PD欠損症 / NDIII / COI / PCR / 原虫 / squirrel monkey / vaccine / paramyosin / monoclonal IgE / schistosomiasis japonica / リスザル / パラミオシン / モノクローナルIgE / 日本住血吸虫症 / 免疫学 / 感染症 / 抗マラリア薬 / 結晶構造解析 / 芽殖孤虫 / フマル酸還元酵素 / 薬剤標的分子 / フラボプロテイン / 酵素の触媒機構 / ユビキノン / 基質結合部位 / 阻害剤 / 共結晶 / X線結晶構造解析 / ユビキノン結合部位 / NADH dehydrogenase / 電子線クライオトモグラフフィー / 3Dプリンター / 蛋白質 / ナノバイオ / 分子モーター / 電子顕微鏡 / 電子線クライオトモグラフィー / 3Dプリンター / 高速AFM / 質量分析 / ビデオライブラリー / スマートフォンアプリ / 技術開発・支援 / 急速凍結レプリカ法 / クライオ電子顕微鏡 / エクソソーム / スカベンジャー受容体 / リポ蛋白 / ケミカルバイオロジー / 新規薬剤標的 / ピリミジン生合成経路 / フマル酸呼吸 / 癌微小環境 / 知的障害者 / 知的障碍者 / コミュニティベースオーガナイゼイション / 紛争後社会 / ケア / 世帯構造 / コミュニティベースドオーガナイゼイション / 知的障害 / ウガンダ共和国 / うなづき症候群 / glutamine antagonist / Acivicin / carbamoyl-phosphate synthetase II (EC 6.3.5.5) / pyrimidine nucleotides / parasitic protozoa (Trypanosomatidae) / グルタミン / 代謝調節 / カルバミルリン酸合成酵素(EC6.3.5.5) / 増殖阻害 / グルタミン拮抗剤 / acivicin / カルバミルリン酸合成酵素II(EC6.3.5.5) / ピリミジンヌクレオチド / トリパノソーマ科寄生原虫 / Biomphalaria / Oncomelania / Paragonimus / Ascaris / environmental adaptation / PEPCK-succinate pathway / Fumarate reductase system / チトクロム / 高速液体クロマトグラフ / 複合体【II】 / 嫌気的エネルギー代謝 / 電子伝達系 / 平巻貝 / 宮入貝 / 肺吸虫 / 回虫 / 環境適応 / PEPCK-コハク酸経路 / フマル酸還元系 / Gene analysis / Vaccine candidate antigen / Human malaria parasite / Plasmod ium falciparum / Myanmar : Indonesia : Vietnam / 熱帯熱マラリア原虫 / ミャンマー:インドネシア:ベトナム:カンボジア / ワクチン抗原 / ヒトマラリア原虫 / 分子疫学調査 / ミャンマー:インドネシア:ベトナム / Chemotherapy / Derivatives / Mice / Ascofuranone / Cyanide insensitive alternative oxidase / Rhodesian sleeping sickness / アフリカ睡眠病 / 組み換え酵素 / 治療薬 / 血流 / ヤギ / アフリカトリパノソーマ / ローデシア睡眼病 / 化学療法 / 誘導体 / マウス / アスコフラノン / シアン耐性呼吸酵素 / ローデシア睡眠病 / complex I / acetogenin / respiratory inhibitor / 複合体-I / 呼吸鎖酵素阻害剤 / elongation factor Tu / translation / nematode / EF-Tu / タンパク質合成 / 線形動物 / Molecular analysis / New Plasmodium ovale / New Plasmodium malariae / New human malaria / Myanmar ; Vietnam ; Cambodia ; Indonesia ; Thailand / 新型卵形マラリア原虫 / 新型ヒトマラリア原虫 / ミャンマー:ベトナム:カンボジア:インドネシア:タイ / Mitochondria / Respiratory Enzymes / Respiratory Inhibitor / 構造活性相関 / 呼吸鎖酵素 / new type / field survey / SSUrRNA gene / Plasmodium malariae / Myanmar / Southeast Asia / malaria / リボゾームRNA遺伝子 / インドネシア / ベトナム / タイ / 卵形マラリア / 新型種 / 疫学調査 / SSUrRNA遺伝子 / 四日熱マラリア原虫 / ミャンマー / 東南アジア / Molecular Phylogenetics / Marine Mammals / Diphyllobothriidae / Sparganum ploriferum / 分子系統 / 海産哺乳類 / 裂頭条虫科 / antibodies / phage display method / faiciparm malaria / Thalland / genes related to servere malaria / mouse severe malaria / ヘパラン硫酸 / 補体レセプター1型(CR1) / ロゼット / マラリア流行 / 重症化 / マラリア抗原 / マラリア抗体 / 熱帯熱マラリア患者 / CD14 / 第18染色体 / 抗体 / ファージ・ディスプレー法 / 熱帯マラリア / タイ国 / 重症マラリア感受性遺伝子 / マウス重症マラリア / target molecule / Plasmodium falciparum / protozoa / tropical fever / antisense / Screening / Anti-malaria drug / Malaria / インターネット / スクリーニンヅ / マラリア治療薬 / ATPase / 標的分子 / P.falciparum / 熱帯熱 / アンチセンス / スクリーニング / protective immunity / 防御免疫 / 中間宿主 / 終宿主 / 駆虫薬 / 羊 / 犬 / ミトコンドリア呼吸鎖 / 感染源対策 / 人獣共通感染症 / 単包条虫 / 多包条虫 / 駆虫 / 青海省 / 中国 / 薬剤開発 / 疫学 / エキノコックス / 研究マトリックス / 宿主応答機構 / 病原性発現機構 / 増殖機構 / 感染現象 / 生態系 / マラリア伝播 / 遺伝子 / Plasmodium / 電子伝達複合体 / グラフィックス / コハク酸脱水素酵素 / O_2還元反応中間体 / チトクロムbc_1 / チトクロム酸化酵素 / プロトン輸送機構 / オキシダーゼ結晶化条件 / ヒドロゲナーゼFeS,Ni中心 / 回虫発生とSDH,FRD / bc_l低分解能結晶構造 / bc_l反応機構と2量体 / 好アルカリ性細菌のチトクロムc酸化酵素 / ヒドロゲナーゼの活性中心 / チトクロム酸化酵素の反応速度論 / オキシダーゼ反応機構 / 回虫の複合体II / bc_1低分解能結晶構造 / bc_1の結晶化 / プレロセルコイド / 病態 / 免疫応答 / 実験的芽殖孤虫症 / アミノ酸配列 / フラビン結合領域 / 回虫ミトコンドリア / 複合体II / 嫌気的エネルギ-代謝 Less
  • Research Projects

    (44 results)
  • Research Products

    (182 results)
  • Co-Researchers

    (124 People)
  •  Causative agent and pathogenesis of "nodding syndrome" epilepsy in AfricaPrincipal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Nagasaki University
  •  Investigation of sulfide metabolism pathway from Schistosoma mansoniPrincipal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 49040:Parasitology-related
    • Research Institution
      Nagasaki University
  •  Insights on the mechanism of mitochondrial diseasesPrincipal Investigator

    • Principal Investigator
      Kita Kiyoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Nagasaki University
  •  Study on the reaction mechanism of type II NADH dehydrogenase by structural and biochemical analyses of the enzyme-inhibitor interaction.

    • Principal Investigator
      Yamashita Tetsuo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kagawa University
  •  Chemical biology of cyanide-insensitive Trypanosome alternative oxidase.Principal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Parasitology (including sanitary zoology)
    • Research Institution
      Nagasaki University
      The University of Tokyo
  •  An epidemiological study on echinococcosis in Qinghai, China, and development of a chemotherapeutic drug for humans and domestic animals

    • Principal Investigator
      Nonaka Nariaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      University of Miyazaki
  •  Interdisciplinary research aiming at establishing treatment and care for Nodding Syndrome in Uganda

    • Principal Investigator
      TAKEI Yayoi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Area studies
    • Research Institution
      Sophia University
  •  Pyrimidine biosynthesis and energy metabolism in cancer microenvironment

    • Principal Investigator
      INAOKA KEN DANIEL
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo
  •  Host Sterol Supply to Plasmodium Parasites as the Therapeutic Target in Malaria

    • Principal Investigator
      ISO-O Naoyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokyo
  •  Generalization of harmonized supramolecular motility machinery and its diversity

    • Principal Investigator
      MIYATA Makoto
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka City University
  •  Growth and pathogenicity of helminthesPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Matrix of Infection Phenomena

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2006 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Microbial Chemistry Research Foundation
      The University of Tokyo
  •  Support for Research Techniques and Materials

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Microbial Chemistry Research Foundation
  •  Diversity of energy transducing mechanism by organella from the parasites such as PlasmodiumPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      The University of Tokyo
  •  低酸素適応における寄生虫ミトコンドリア特異的呼吸酵素群の生理機能Principal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      The University of Tokyo
  •  感染現象の研究マトリックスを構築するための企画調査研究

    • Principal Investigator
      NOMOTO Akio
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  Study on respiratory enzyme complex I based on the organic synthesis of acetogenin analogues

    • Principal Investigator
      MIYOSHI Hideto
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      Kyoto University
  •  DEVELOPMENT OF CHEMOTHERAPY FOR AFRICAN TRYPANOSOMIASIS USING ASCOFURANONE

    • Principal Investigator
      YABU Yoshisada
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Nagoya City University
  •  Molecular epidemiological study on the SERA antigen gene in Plasmodium falciparum

    • Principal Investigator
      KAWAMOTO Fumihiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      OITA UNIVERSITY
  •  Synthesis of functional probes toward elucidation of the function of respiratory enzymes of Caenorhabditis elegans.

    • Principal Investigator
      MIYOSHI Hideto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioproduction chemistry/Bioorganic chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular epidemiology on distribution of new human malaria parasite and G6PD deficiency

    • Principal Investigator
      KAWAMOTO Fumihiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      OITA UNIVERSITY
      大分医科大学
  •  Study of nematode mitochondrial translation system using parasitic nematodes

    • Principal Investigator
      WATANABE Yoh-ichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      The University of Tokyo
  •  Molecular organization and physiological functions of the respiratory chain specific for mitochondria from PlasmodiumPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  マラリア原虫ミトコンドリア特異的呼吸酵素群の分子構築と生理機能Principal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  低酸素適応における回虫ミトコンドリア特異的呼吸酵素群の生理機能Principal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  Physiological function of respiratory enzymes specific for parasite mitochondria in the adaptation to low oxygen tensionPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  マラリア制圧の総合戦略

    • Principal Investigator
      TANABE Kazuyuki
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Osaka Institute of Technology
  •  Molecular organization of mitochondrial quinol-fumarate reductase and its role in oxygen adaptation.Principal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  Genomic factors of parasites and human beings on malaria severity

    • Principal Investigator
      AIKAWA Masamichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokai University
  •  Molecular phylogenetics of diphyllobothriid cestodes with special reference to the species identification of Sparganum proliferum.

    • Principal Investigator
      KURAMOCHI Toshiaki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      National Science Museum, Tokyo
  •  Surveys on malaria and gene analysis in Southeast Asia

    • Principal Investigator
      KAWAMOTO Fumihiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Nagoya University
  •  サブユニット間ヘム架橋型シトクロムbにおけるヘム特異的アセンブリー機構Principal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  サブユニット間ヘム架橋型シトクロムbにおけるヘム特異的アセンブリー機構Principal Investigator

    • Principal Investigator
      北 潔
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Molecular approach for malaria controlPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi, 小島 荘明 (小島 莊明)
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Development of Anti-malarial Drug and it's Molecular Target

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Okayama University
  •  Selective expression of the mitochondrial genes from Ascaris suumPrincipal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  Development of schistosomiasis vaccines by using squirrel monkeys

    • Principal Investigator
      KOJIMA Somei
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  呼吸鎖電子伝達酵素の分子構築

    • Principal Investigator
      松原 央
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Molecular and immunological studies on mechanisms of protective immunity to schistosomiasis japonica

    • Principal Investigator
      KOJIMA Somei
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  芽殖孤虫および芽殖孤虫症に関する基礎研究

    • Principal Investigator
      小島 荘明, KOJIMA Somei
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  回虫ミトコンドリア呼吸系における低酸素圧適応機構の解析

    • Principal Investigator
      OYA Hiroshi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Juntendo University
  •  The Function of B Cytochrome in Complex II (Succinate-Ubiquinone Oxidoreductase)Principal Investigator

    • Principal Investigator
      KITA Kiyoshi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Juntendo University School of Medicine
  •  An analysis of fumarate reductase systems in parasitic helminths and various intermediate molluscan hosts

    • Principal Investigator
      OYA Hiroshi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Juntendo Uiversity School of Medicine
  •  Comparative studies on pyrimidine nucleotide biosynthesis characteristic of parasitic protozoa

    • Principal Investigator
      AOKI Takashi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Juntendo University School of Medicine

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent Other

  • [Book] The timing of worm exclusion in dogs repeatedly infected with the cestode Echinococcus multilocularis. In: Echinococcosis (ed: Tonay Incebo)2017

    • Author(s)
      Enkai、S., Sakamoto, K., Kaneko,M., Kouguchi, H., Irie, T., Yagi, K., Matsumoto, J., Oku, Y., Katakura, K., Fujita, O., Nozaki, T., Kita, K.
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Book] Kala Azar in South Asia2017

    • Author(s)
      Nozomu Nihashi, Daniel Ken Inaoka, Chiaki Tsuge, Emmanuel Oluwadare Balogun, Yasutaka Osada, Yasuyuki Goto, Yoshitsugu Matsumoto, Takeshi Nara, Tatsushi Mogi, Shigeharu Harada, Kita Kiyoshi
    • Total Pages
      309
    • Publisher
      Springer International Publishing
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Book] Cytochrome Complexes:Evolution, Structures, Energy Transduction, and Signaling2016

    • Author(s)
      Luke Young, Benjamin May, Tomoo Shiba, Shigeharu Harada, Daniel Ken Inaoka, Kiyoshi Kita, Anthony L. Moore
    • Total Pages
      739
    • Publisher
      Springer Netherlands
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Book] 抗眠り病薬アスコフラノン ー自然からの贈り物ー in 生命科学から創薬へのイノベーション(米田悦啓、堤康央、石井健 編)2014

    • Author(s)
      北潔、志波智生、稲岡ダニエル健、原田繁春
    • Total Pages
      7
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Book] 「クリプトスポリジウム」感染症事典2012

    • Author(s)
      原田倫世、北潔
    • Publisher
      オーム社
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Book] 微生物資源国際戦略2009

    • Author(s)
      北潔
    • Total Pages
      448
    • Publisher
      サイエンスフォーラム社
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Book] 「眠り病は眠らない」岩波科学ライブラリー2008

    • Author(s)
      山内一也、北潔
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase2021

    • Author(s)
      Hartuti Endah Dwi、Sakura Takaya、Tagod Mohammed S. O.、Yoshida Eri、Wang Xinying、Mochizuki Kota、Acharjee Rajib、Matsuo Yuichi、Tokumasu Fuyuki、Mori Mihoko、Waluyo Danang、Shiomi Kazuro、Nozaki Tomoyoshi、Hamano Shinjiro、Shiba Tomoo、Kita Kiyoshi、Inaoka Daniel Ken
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 13 Pages: 7236-7236

    • DOI

      10.3390/ijms22137236

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436
  • [Journal Article] Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii2021

    • Author(s)
      Acharjee Rajib、Talaam Keith、Hartuti Endah、Matsuo Yuichi、Sakura Takaya、Gloria Bundutidi、Hidano Shinya、Kido Yasutoshi、Mori Mihoko、Shiomi Kazuro、Sekijima Masakazu、Nozaki Tomoyoshi、Umeda Kousuke、Nishikawa Yoshifumi、Hamano Shinjiro、Kita Kiyoshi、Inaoka Daniel
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 15 Pages: 7830-7830

    • DOI

      10.3390/ijms22157830

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-18KK0454, KAKENHI-PROJECT-20H00620, KAKENHI-PROJECT-19H03436
  • [Journal Article] Weak O2 binding and strong H2O2 binding at the non-heme diiron center of Trypanosome Alternative Oxidase2021

    • Author(s)
      S.Yamasaki, M.Shoji, M.Kayanuma, V.Sladek, D.K.Inaoka, Y.Matsuo, T.Shiba, L.Young, A.L.Moore, K.Kita, Y.Shigeta
    • Journal Title

      Biochimica et Biophysica Acta - Bioenergetics

      Volume: 1862 Issue: 4 Pages: 148356-9

    • DOI

      10.1016/j.bbabio.2020.148356

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05088, KAKENHI-PLANNED-20H05453, KAKENHI-PROJECT-19K07523, KAKENHI-PUBLICLY-20H05497, KAKENHI-PROJECT-19H03436
  • [Journal Article] Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection2021

    • Author(s)
      Talaam Keith Kiplangat、Inaoka Daniel Ken、Hatta Takeshi、Tsubokawa Daigo、Tsuji Naotoshi、Wada Minoru、Saimoto Hiroyuki、Kita Kiyoshi、Hamano Shinjiro
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: 65 Issue: 10

    • DOI

      10.1128/aac.00418-21

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436, KAKENHI-PROJECT-21K06996, KAKENHI-PROJECT-17H01684, KAKENHI-PROJECT-21H04852
  • [Journal Article] The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.2020

    • Author(s)
      Mochizuki K, Inaoka DK, Mazet M, Shiba T, Fukuda K, Kurasawa H, Millerioux Y, Boshart M, Balogun EO, Harada S, Hirayama K, Bringaud F, Kita K.
    • Journal Title

      Biochim Biophys Acta Bioenerg

      Volume: 1861(11) Issue: 11 Pages: 148283-148283

    • DOI

      10.1016/j.bbabio.2020.148283

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436
  • [Journal Article] Identification of small molecule inhibitors of human COQ72020

    • Author(s)
      Tsuganezawa Keiko、Sekimata Katsuhiko、Nakagawa Yukari、Utata Rei、Nakamura Kana、Ogawa Naoko、Koyama Hiroo、Shirouzu Mikako、Fukami Takehiro、Kita Kiyoshi、Tanaka Akiko
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 28 Issue: 1 Pages: 115182-115182

    • DOI

      10.1016/j.bmc.2019.115182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Journal Article] Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum2019

    • Author(s)
      Araki Yasuko、Awakawa Takayoshi、Matsuzaki Motomichi、Cho Rihe、Matsuda Yudai、Hoshino Shotaro、Shinohara Yasutomo、Yamamoto Masaichi、Kido Yasutoshi、Inaoka Daniel Ken、Nagamune Kisaburo、Ito Kotaro、Abe Ikuro、Kita Kiyoshi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 未定 Issue: 17 Pages: 8269-8274

    • DOI

      10.1073/pnas.1819254116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15679, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-18KK0454, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-19H03436, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095
  • [Journal Article] Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system2019

    • Author(s)
      Pang, Y., Yamamoto, H., Sakamoto, H., Oku, M., Mutungi, J.K., Sahani, M.H., Kurikawa, Y., Kita, K., Noda, N.N., Sakai, Y., Jia, H., Mizushima, N.
    • Journal Title

      Nat. Struct. Mol. Biol.

      Volume: 26 Issue: 4 Pages: 289-296

    • DOI

      10.1038/s41594-019-0204-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03670, KAKENHI-PROJECT-16K07689, KAKENHI-PROJECT-19H03436
  • [Journal Article] Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors2018

    • Author(s)
      Yamashita Tetsuo, Inaoka Daniel Ken, Shiba Tomoo, Oohashi Takumi, Iwata So, Yagi Takao, Kosaka Hiroaki, Miyoshi Hideto, Harada Shigeharu, Kita Kiyoshi, Hirano Katsuya
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 2427-2427

    • DOI

      10.1038/s41598-018-20775-6

    • NAID

      120006532084

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17420, KAKENHI-PROJECT-15K07005
  • [Journal Article] Re-identification of the ascofuranone-producing fungus Ascochyta viciae as Acremonium sclerotigenum2017

    • Author(s)
      Hijikawa, Y., Matsuzaki, M., Suzuki, S., Inaoka, D. K., Tatsumi, R., Kido, Y. and Kita, K.
    • Journal Title

      J. Antibiotics

      Volume: 70 Issue: 3 Pages: 304-307

    • DOI

      10.1038/ja.2016.132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Journal Article] Design and Synthesis of Potent Substrate-based Inhibitors of the Trypanosoma cruzi Dihydroorotate Dehydrogenase2017

    • Author(s)
      D. K. Inaoka, M. Iida, S. Hashimoto, T. Tabuchi,T. Kuranaga, E. O. Balogun, T. Honma, A. Tanaka, S. Harada, T. Nara, K. Kita, M. Inoue
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 25 Issue: 4 Pages: 1465-1470

    • DOI

      10.1016/j.bmc.2017.01.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01130, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J12403, KAKENHI-PROJECT-16K15268
  • [Journal Article] Development of a new air-stable structure-simplified nafuredin-γ analog as a potent and selective nematode complex I inhibitor2017

    • Author(s)
      Masaki Ohtawa, Shiho Arima, Risa Shimizu, Naomi Hanatani, Eri Shimizu, Kazuro Shiomi, Kiyoshi Kita, Satoshi Omura,Tohru Nagamitsu
    • Journal Title

      The Journal of Antibiotics(Tokyo)

      Volume: 印刷中 Issue: 5 Pages: 647-654

    • DOI

      10.1038/ja.2017.16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26304041
  • [Journal Article] Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion.2017

    • Author(s)
      Francisco Jose Fueyo Gonzalez, Godwin U. Ebiloma, Carolina Izquierdo Garcia, Victor Bruggeman, Jose Maria Sanchez Villamanan, Anne Donachie, Emmanuel Oluwadare Balogun, Daniel Ken Inaoka, Tomoo Shiba, Shigeharu Harada, Kiyoshi Kita, Harry P. de Koning, Christophe Dardonville
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 60(4) Issue: 4 Pages: 1509-1522

    • DOI

      10.1021/acs.jmedchem.6b01740

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26440027
  • [Journal Article] Investigation into the Physiological Significance of the Phytohormone Abscisic Acid in Perkinsus marinus, an Oyster Parasite Harboring a Non-Photosynthetic Plastid2016

    • Author(s)
      Sakamoto, H, Suzuki, S., Nagamune, K., Kita, K., Matsuzaki, M.
    • Journal Title

      J. Eukaryot. Microbiol.

      Volume: 印刷中 Issue: 4 Pages: 440-446

    • DOI

      10.1111/jeu.12379

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04726, KAKENHI-WRAPUP-16H01703, KAKENHI-PROJECT-26253025
  • [Journal Article] Investigation into the ubiquinol-binding site of the trypanosomal alternative oxidase2016

    • Author(s)
      Benjamin May, Luke Young, Mary Albury, Daniel Ken Inaoka, Kiyoshi Kita, Anthony L. Moore
    • Journal Title

      Biochimica et Biophysica Acta (BBA)-Bioenergetics

      Volume: 1857 Pages: e41-e41

    • DOI

      10.1016/j.bbabio.2016.04.309

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Journal Article] Drug selection using bleomycin for transfection of the oyster-infecting parasite Perkinsus marinus2016

    • Author(s)
      Sakamoto H, Kita K, Matsuzaki M
    • Journal Title

      Parasitology International

      Volume: 未定 Issue: 5 Pages: 563-566

    • DOI

      10.1016/j.parint.2016.04.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23117004, KAKENHI-PROJECT-26253025
  • [Journal Article] Parasites resistant to the anti-malarial atovaquone fail to transmit by mosquitoes.2016

    • Author(s)
      Goodman, C. D., Siregar, J., Mollard, V., Vega-Rodriguez, J., Syafruddin, D., Matsuoka, H., Matsuzaki, M., Toyama, T., Sturm, A., Cozijnsen, A., Jacobs-Loreno, M., Kita, K., Marzuki, S. and McFadden, G. I.
    • Journal Title

      Science

      Volume: 352 Pages: 349-353

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Journal Article] The Open Form Inducer Approach for Structure-Based Drug Design2016

    • Author(s)
      D. K. Inaoka, M. Iida, T. Tabuchi, T. Honma, N. Lee, S. Hashimoto, S. Matsuoka, T. Kuranaga, K. Sato, T. Shiba, K. Sakamoto, E. O. Balogun, S. Suzuki, T. Nara, J. R. Rocha, C. A. Montanari, A. Tanaka, M. Inoue, K. Kita, S. Harada
    • Journal Title

      PLoS ONE

      Volume: 11 Issue: 11 Pages: e0167078-e0167078

    • DOI

      10.1371/journal.pone.0167078

    • NAID

      120006987593

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01130, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J12403, KAKENHI-PROJECT-26304041, KAKENHI-PROJECT-26460504, KAKENHI-PROJECT-16K15268
  • [Journal Article] Structural study of MPN387, an essential protein for gliding motility of a human pathogenic bacterium, Mycoplasma pneumoniae2016

    • Author(s)
      Kawakita Y, Kinoshita M, Furukawa Y, Tulum I, Tahara YO, Katayama E, Namba K, Miyata M
    • Journal Title

      Journal of Bacteriology

      Volume: 198 Issue: 17 Pages: 2352-9

    • DOI

      10.1128/jb.00160-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24117002, KAKENHI-PROJECT-25000013, KAKENHI-ORGANIZER-24117001
  • [Journal Article] Hit and lead criteria in drug discovery for infectious diseases of the developing world2015

    • Author(s)
      Katsuno, K., Burrows, J.N., Duncan, K., van Huijsduijnen, R.H., Kaneko, T., Kita, K., Mowbray, C.E., Schmatz, D., Warner, P. & Slingsby, B.T.
    • Journal Title

      Nat. Rev. Drug Discov.

      Volume: 14 Pages: 751-758

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Journal Article] In vivo curative and protective potential of orally administrated 5-aminolevulinic acid plus ferrous iron against malaria2015

    • Author(s)
      Suzuki S, Hikosaka K, Balogun EO, Komatsuya K, Niikura M, Kobayashi F, Takahashi K, Tanaka T, Nakajima M, Kita K.
    • Journal Title

      Antimicrobial Agents and Chemotherapy

      Volume: 59 Issue: 11 Pages: 6960-6967

    • DOI

      10.1128/aac.01910-15

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08449, KAKENHI-PROJECT-15K08451, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J04920
  • [Journal Article] Lactate retards the development of erythrocytic stages of the human malaria parasite Plasmodium falciparum.2015

    • Author(s)
      Hikosaka K, Hirai M, Komatsuya K, Ono Y, Kita K.
    • Journal Title

      Parasitol Int

      Volume: 64 Issue: 3 Pages: 301-303

    • DOI

      10.1016/j.parint.2014.08.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26860277, KAKENHI-PROJECT-24590501
  • [Journal Article] Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method2015

    • Author(s)
      Ryunosuke Yoshino, Nobuaki Yasuo, Daniel Ken Inaoka, Yohsuke Hagiwara, Kazuki Ohno, Masaya Orita, Masayuki Inoue, Tomoo Shiba, Shigeharu Harada, Teruki Honma, Emmanuel Oluwadare Balogun, Josmar Rodrigues Da Rocha, Carlos Alberto Montanari, Kiyoshi Kita, Masakazu Sekijima
    • Journal Title

      PLoS One

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Journal Article] 1.Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria2015

    • Author(s)
      Inaoka DK, Shiba T, Sato D, Balogun EO, Sasaki T, Nagahama M, Oda M, Matsuoka S, Ohmori J, Honma T, Inoue M, Kita K, Harada S
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 16 Issue: 7 Pages: 15287-15308

    • DOI

      10.3390/ijms160715287

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440027, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26870119
  • [Journal Article] Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria2015

    • Author(s)
      Daniel Ken Inaoka, Tomoo Shiba, Dan Sato, Emmanuel Oluwadare Balogun, Tsuyoshi Sasaki, Madoka Nagahama, Masatsugu Oda, Shigeru Matsuoka, Junko Ohmori, Teruki Honma, Masayuki Inoue, Shigeharu Harada, and Kiyoshi Kita
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Journal Article] 2.Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method2015

    • Author(s)
      Yoshino R, Yasuo N, Inaoka DK, Hagiwara Y, Ohno K, Orita M, Inoue M, Shiba T, Harada S, Honma T, Balogun EO, da Rocha JR, Montanari CA, Kita K, Sekijima M
    • Journal Title

      PLoS One

      Volume: 10 Issue: 5 Pages: 1-15

    • DOI

      10.1371/journal.pone.0125829

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440027, KAKENHI-PROJECT-24240044, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15H02776, KAKENHI-PROJECT-26870119
  • [Journal Article] Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex.2015

    • Author(s)
      Siregar JE, Kurisu G, Kobayashi T, Matsuzaki M, Sakamoto K, Mi-Ichi F, Watanabe Y, Hirai M, Matsuoka H, Syafruddin D, Marzuki S, Kita K.
    • Journal Title

      Parasitol Int

      Volume: 64 Issue: 3 Pages: 295-300

    • DOI

      10.1016/j.parint.2014.09.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24112705, KAKENHI-PUBLICLY-26117719, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-24590501
  • [Journal Article] Conservation of two distinct types of 100S ribosome in bacteria.2013

    • Author(s)
      Ueta, M., et al
    • Journal Title

      Genes to Cells

      Volume: 18 Issue: 7 Pages: 554-574

    • DOI

      10.1111/gtc.12057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21227006, KAKENHI-PROJECT-23651126, KAKENHI-ORGANIZER-24117001, KAKENHI-PROJECT-25840002
  • [Journal Article] Critical roles of the mitochondrial complex II in oocyst formation of rodent malaria parasite Plasmodium berghei2012

    • Author(s)
      A., Hirai, M., Tanaka, Q. T., Watanabe, Y., Matsuoka, H. and Kita, K.
    • Journal Title

      J. Biochem

      Volume: (掲載確定)(印刷中)

    • NAID

      10031166137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade2012

    • Author(s)
      Tachibana, S., Sullivan, S. A., Kawai, S., Nakamura, S., Kim, H. R., Goto, N., Arisue, N., Palacpac, N., Honma, H., Yagi, M., Tougan, T., 5, Katakai, Y., Kaneko, O., Mita, T., Kita, K., Yasutomi, Y., Sutton, P. L., Shakhbatyan, R., Horii, T., Yasunaga, T., Barnwell, J. W., Escalante, A. A., Carlton, J. M. and Tanabe, K
    • Journal Title

      Nature Genet

      Volume: (掲載確定)(印刷中)

    • NAID

      120006985529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Concatenated mitochondrial DNA of the coccidian parasite Eimeria tenella2011

    • Author(s)
      Hikosaka, K., Nakai, Y., Watanabe, Y., Tachibana, S., Arisue, N., Palacpac, N. M., Toyama, T., Honma, H., Horii, T., Kita, K. and Tanabe, K
    • Journal Title

      Mitochondrion

      Volume: 11 Pages: 273-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Contribution of the FAD and quinone binding sites to the production of reactive oxygen species (ROS) from Ascaris suum mitochondrial complex II.2010

    • Author(s)
      Paranagama, M.P., Sakamoto, K., Amino, H., Awano, M., Miyoshi, H., Kita, K.
    • Journal Title

      Mitochondrion 10

      Pages: 158-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Extensive frameshift at all AGG and CCC codons in the mitochondrial cytochrome c oxidase subunit 1 gene of Perkinsus marinus(Alveolata ; Dinoflagellata)2010

    • Author(s)
      Masuda, I., Matsuzaki, M. and Kita, K
    • Journal Title

      Nucleic Acids Research

      Volume: 38 Pages: 6186-6194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner, is essential for the parasite's survival2009

    • Author(s)
      Sasaki N., Hirai, M., Maeda, K., Yui, R., Itoh, K., Namiki, S., Morita, T., Hata, M., Murakami-Murofushi, K., Matsuoka, H., Kita, K., Sato, S
    • Journal Title

      FEBS Lett

      Volume: 583 Pages: 1446-1450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Regulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunit.2009

    • Author(s)
      Tomitsuka, E., Kita, K., Esumi, H.
    • Journal Title

      Proc.Jap.Acad. B85

      Pages: 258-265

    • NAID

      130000138032

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi is Composed of Twelve Peptides Including a Heterodimeric Ip Subunit2009

    • Author(s)
      Morales, J., Mogi, T., Mineki, S., Takashima, E., Mineki, R., Hirawake, H., Sakamoto, K., . mura, S. and Kita, K
    • Journal Title

      J. Biol. Chem

      Volume: 284 Pages: 7255-7263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with specific inhibitor, flutolanil.2009

    • Author(s)
      Osanai, A., Harada, S., Sakamoto, K., Shimizu, H., Inaoka, D. K., Kita, K.
    • Journal Title

      Acta Crystallographica F65

      Pages: 941-944

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Mitochondrial Dehydrogenases in the Aerobic Respiratory Chain of the Rodent Malaria Parasite Plasmodium yoelii yoelii2009

    • Author(s)
      Kawahara,K., Mogi, T., Tanaka, Q. T., Hata, M., Miyoshi, H.and Kita K.
    • Journal Title

      J. Biochem 145

      Pages: 229-237

    • NAID

      10026301704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Mitochondrial Dehydrogenases in the Aerobic Respiratory Chain of the Rodent Malaria Parasite Plasmodium yoelii yoelii2009

    • Author(s)
      Kawahara, K., Mogi, T., Tanaka, Q. T., Hata, M., Miyoshi, H. and Kita K
    • Journal Title

      J. Biochem

      Volume: 145 Pages: 229-237

    • NAID

      10026301704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Freezing survival of the nematode Caenorhabditis elegans in the presence of a cryoprotectant.2009

    • Author(s)
      Hayashi, M., Oguma, T., Amino, H., Kita, K., Murase, N.
    • Journal Title

      Cryobiology and Cryotechnology 55

      Pages: 9-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner,is essential for the parasite's survival2009

    • Author(s)
      Sasaki, N., Hirai, M., Maeda, K., Yui, R., Itoh, K., Namiki, S., Morita, T., Hata, M., Murakami-Murofushi, K., Matsuoka, H., Kita, K., Sato, S.
    • Journal Title

      FEBS Lett. 583

      Pages: 1446-1450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi is Composed of Twelve Peptides Including a Heterodimeric Ip Subunit2009

    • Author(s)
      Morales, J., Mogi, T., Mineki, S., Takashima, E., Mineki, R., Hirawake, H., Sakamoto, K., mura, S.and Kita, K.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 7255-7263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Change of subunit composition of mitochondrial complex II (Succinate-ubiquinone reductase/Quinol-fumarate reductase) in Ascaris suum during the migration in the experimental host2008

    • Author(s)
      Iwata F., Shinjyo N., Amino H., Sakamoto K., Islam M. K., Tsuji N. and Kita K.
    • Journal Title

      Parasitol. Int. 57

      Pages: 54-61

    • NAID

      10020151144

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Anaerobic NADH-Fumarate Reductase System Is Predominant in the Respiratory Chain of Echinococcus multilocularis, Providing a Novel Target for the Chemotherapy of Alveolar Echinococcosis2008

    • Author(s)
      Matsumoto J., Sakamoto K., Shinjyo N., Kido Y., Yamamoto N., Yagi K., Miyoshi H., Nonaka N., Katakura K., Kita K. and Oku Y.
    • Journal Title

      Antimicrob. Agents. Chemother. 52

      Pages: 164-170

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Anaerobic NADH-Fumarate Reductase System Is Predominant in the Respiratory Chain of Echinococcus multilocularis, Providing a Novel Target for the Chemotherapy of Alveolar Echinococcosis.2008

    • Author(s)
      Matsumoto J., Sakamoto K., Shinjyo N., Kido Y., Yamamoto N., Yagi K., Miyoshi H., Nonaka N., Katakura K., Kita K., Oku Y.
    • Journal Title

      Antimicrob.Agents.Chemother. 52

      Pages: 164-170

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Mutation underlying resistance of Plasmodium berghei to atovaquone in the quinone binding domain 2 (Qo_2) of the cytochrome b gene.2008

    • Author(s)
      Siregar J. E., Syafruddin D., Matsuoka H, Kita K., and Marzuki S.
    • Journal Title

      Parasitol. Int. 57

      Pages: 229-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Screening of detergents for solubilization, purification and crystallization of membrane proteins : a case study on succinate : ubiquinone oxidoreductase from Escherichia coli.2008

    • Author(s)
      Shimizu, H., Nihei, C., Inaoka, D. K., Mogi, T., Kita, K., Harada, S.
    • Journal Title

      Acta Crystallographica F64

      Pages: 858-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] A cryptic algal group unveiled: a plastid biosynthesis pathway in the oyster parasite Perkinsus marinus2008

    • Author(s)
      Matsuzaki M., Kuroiwa H., Kuroiwa T., Kita K., and Nozaki H.
    • Journal Title

      Mol. Biol. Evolution 25

      Pages: 1167-1179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Change of subunit composition of mitochondrial complex II (Succinate-ubiquinone reductase/Quinol-fumarate reductase) in Ascaris suum during the migration in the experimental host.2008

    • Author(s)
      Iwata F., Shinjyo N., Amino H., Sakamoto K., Islam M.K., Tsuji N., Kita K.
    • Journal Title

      Parasitol.Int. 57

      Pages: 54-61

    • NAID

      10020151144

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Screening of detergents for solubilization, purification and crystallization of membrane proteins: a case study on succinate:ubiquinone oxidoreductase from Escherichia coli2008

    • Author(s)
      Shimizu, H., Nihei, C., Inaoka, D. K., Mogi, T., Kita, K. and Harada, S.
    • Journal Title

      Acta Crystallographica F64

      Pages: 858-862

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] A cryptic algal group unveiled : a plastid biosynthesis pathway in the oyster parasite Perkinsus marinus2008

    • Author(s)
      Matsuzaki M., Kuroiwa H., Kuroiwa T., Kita K. and Nozaki H
    • Journal Title

      Mol. Biol. Evolution

      Volume: 25 Pages: 1167-1179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Mitochondria and apicoplast of Plasmodium fakiparum : behaviour on subcellular fractionation and the implication2007

    • Author(s)
      Kobayashi T., Sato, S., Takamiya, S., Komaki-Yasuda, K., Yano, K., Hirata, A., Onitsuka, I., Hata, M., Mi-ichi, F., Tanaka, T., Hase, T., Miyajima, A., Kawazu, S., Watanabe, Y., Kita, K.
    • Journal Title

      Mitochondrion 7

      Pages: 125-132

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Parasitology in Japan:Advances in drug discovery and biochemical studies2007

    • Author(s)
      K.Kita
    • Journal Title

      Trends in Parasitology 23

      Pages: 223-229

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Advances in drug discovery and biochemical studies.2007

    • Author(s)
      K. Kita
    • Journal Title

      Trends in Parasitol. 23

      Pages: 223-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Parasitology in Japan : Advances in drug discovery and biochemical studies.2007

    • Author(s)
      Kita, K., Shiomi K., Omura, S.
    • Journal Title

      Trends in Parasitol. 23

      Pages: 223-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Parasitology in Japan : Advances in drug discovery and biochemical studies.2007

    • Author(s)
      北 潔 et al.
    • Journal Title

      Trends in Parasitol. (印刷中)

    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Journal Article] Parasitology in Japan : Advances in drug discovery and biochemical studies.2007

    • Author(s)
      北 潔 et al.
    • Journal Title

      Trends in Parasitol. (印刷中)

    • Data Source
      KAKENHI-PLANNED-18073004
  • [Journal Article] Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase2006

    • Author(s)
      Sariego, I., Annoura, T., Nara, T., Hashimoto, M., Tsubouchi, A., Iizumi, K., Makiuchi, T., Murata, E., Kita, K., Aoki, T.
    • Journal Title

      Parasitol. Int. 55

      Pages: 1116-1116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Recent advances in research for parasite control in Japan2006

    • Author(s)
      Arizono, N., Shiomi, K., Kita, K., Nakanishi, K., Omura, S.
    • Journal Title

      Trend. Parasitol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Up-regulation of Heme Biosynthesis during Neuronal Differentiation.2006

    • Author(s)
      Shinjyo, N., Kita, K.
    • Journal Title

      J. Biochem. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol.2006

    • Author(s)
      Yabu, Suzuki, Nihei, Minagawa, Hosokawa, Nagai, Kita, Ohta
    • Journal Title

      Parasitology International 55

      Pages: 39-43

    • NAID

      10017321501

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Mutational analysis of the Trypanosoma vivax alternative oxidase : the E(X)eY motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity2005

    • Author(s)
      Nakamura, K., Sakamoto, K.Kido, Y., Fujimoto, Y., Suzuki, T., Suzuki, M., Yabu, Y, Ohta, N., Tsuda, A., Onuma, M., Kita, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 334

      Pages: 593-600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Alternative oxidase (AOX) genes of African trypanosomes: Phylogeny and evolution of AOX and plastid terminal oxidase families.2005

    • Author(s)
      Suzuki, Hashimoto, Yabu, Majiwa, Ohshima, Suzuki, Lu, Hato, Kido, Sakamoto, Nakamura, Kita, Ohta
    • Journal Title

      Journal of Eukaryotic Microbiology 52

      Pages: 374-381

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] A y-Lactone Form Nafuredin, Nafuredin-y, also Inhibits Helminth Complex I2005

    • Author(s)
      Shiomi, K., Ui, H., Suzuki, H., Hatano, H., Nagamitsu, T., Takano, D., Miyadera, H., Yamashita, T., Kita, K., Miyoshi, H., Harder, A., Tomoda, H., Omura, S.
    • Journal Title

      J. Antibiot. 58

      Pages: 50-55

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] 寄生虫のmtDNA2005

    • Author(s)
      北潔
    • Journal Title

      蛋白質核酸酵素 (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590365
  • [Journal Article] PfPDE1, a novel cGMP-specific phosphodiesterase, from the human malaria parasite Plasmodium fakiparum2005

    • Author(s)
      Yuasa, K., Mi-ichi, F., Kobayashi, T., Yamanouchi, M., Kotera, J., Kita, K., Omori, K.
    • Journal Title

      Biochem. J. 392

      Pages: 221-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Mutational analysis of the Trypanosoma vivax alternative oxidase: The E(X)_6Y motif is conserved in both mitochondrial alternative oxidase and plastid terminal oxidase and is indispensable for enzyme activity.2005

    • Author(s)
      Nakamura, Sakamoto, Kido, Fujimoto, Suzuki, Suzuki, Yabu, Ohta, Tsuda, Onuma, Kita
    • Journal Title

      Biochemical and Biophysical Research Communications 334

      Pages: 593-600

    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Rhodoquinone Reaction Site of Mitochondrial Complex I in Parasitic Helminth.2004

    • Author(s)
      Yamashita, T., Ino, T., Miyoshi, H., Sakamoto, K., Osanai, A., Nakamaru-Ogiso, E., Kita, K.
    • Journal Title

      Ascaris suum.Biochim.Biophys.Acta (Bioenergetics) 1608

      Pages: 97-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380083
  • [Journal Article] Rhodoquinone reaction site of mitochondrial complex I, in parasitic helminth, Ascaris suum.2004

    • Author(s)
      Yamashita, T., Ino, T., Miyoshi, H., Sakamoto K., Osanai, A., Nakamaru-Ogiso, E., Kita, K.
    • Journal Title

      Biochim Biophys. Acta (Bioenergetics) 1608

      Pages: 97-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Isolation and characterization of the stage- specific cytochrome b small subunit (CybS) of Ascaris suum complex II from the aerobic respiratory chain of larval mitochondria.2003

    • Author(s)
      Amino, H., Osanai, A., Miyadera, H., Shinjyo, N., Tomitsuka, T., Taka, H., Mineki, R., Murayama, K., Takamiya, S., Aoki, T., Miyoshi, H., Sakamoto, K., Kojima, S., Kita, K.
    • Journal Title

      Mol. Biochem. Parasitol. 128

      Pages: 175-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Parasite mitochondria as a drug target : diversity and dynamic changes during the life cycle.2003

    • Author(s)
      Kita, K., Nihei, C., Tomitsuka, E
    • Journal Title

      Curr. Med. Chem. 10

      Pages: 1241-1253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1, a product of longevity gene of the nematode worm.2003

    • Author(s)
      Adachi, A., Shinjyo, N., Fujita, D., Miyoshi, H., Amino, H.Watanabe, Y., Kita, K.
    • Journal Title

      FEBS Lett. 543

      Pages: 175-179

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Isolation and characterization of the stage-specific cytochrome b small subunit (CybS) of Ascaris suum complex II from the aerobic respiratory chain of larval mitochondria.2003

    • Author(s)
      Amino, H., Osanai, A., Miyadera, H., Shinjyo, N., Tomitsuka, E., Taka, H.Mineki, R.Murayama, K.Takamiya, S.Aoki, T.Miyoshi, H., Sakamoto, K Kojima, S., Kita, K.
    • Journal Title

      Mol.Biochem.Parasitol. 128

      Pages: 175-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380083
  • [Journal Article] Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).2003

    • Author(s)
      Miyadera, H., Shiomi, K., Ui, H., Yamaguchi, Y., Masuma, R., Tomoda, H., Miyoshi, H., Osanai, A., Kita, K., Omura, S.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 100

      Pages: 473-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).2003

    • Author(s)
      Miyadera, H., Shiomi, K., Ui, H., Yamaguchi Y., Masuma, R., Tomoda, H., Miyoshi, H., Osanai, A., Kita, K., Ohmura, S.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 473-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380083
  • [Journal Article] Complex II from phototrophic purple bacterium Rhodoferax fermentans displays rhodoquinol-fumarate reductase activity.2003

    • Author(s)
      Miyadera, H., Hiraishi, A., Miyoshi, H., Sakamoto, K., Mineki, R., Murayama, K., Nagashima, K., Matsuura, K., Kojima, S., Kita, K.
    • Journal Title

      Eur.J.Biochem. 270

      Pages: 1863-1874

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15380083
  • [Journal Article] Direct evidence for expression of Type II flavoprotein subunit in human complex II (succinate-ubiquinone reductase).2003

    • Author(s)
      Tomitsuka, E., Goto, Y., Taniwaki, M., Kita, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 311

      Pages: 774-779

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Direct evidence for two distinct forms of the flavoprotein subunit of human mitochondrial complex II (succinate-ubiquinone reductase).2003

    • Author(s)
      Tomitsuka, E., Hirawake, H., Goto, Y., Taniwaki, M., Harada, S., Kita, K.
    • Journal Title

      J. Biochem. 134

      Pages: 191-195

    • NAID

      10012056682

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Purification of active recombinant Trypanosome Alternative Oxidase.2003

    • Author(s)
      Nihei, C., Fukai, Y., Kawai, K., Osanai, A., Yabu, Y., Suzuki, T., Ohta, N., Minagawa, N., Nagai, K., Kita, K.
    • Journal Title

      FEBS Lett. 538

      Pages: 35-40

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Complex II from Phototrophic Purple Bacterium Rhodoferax fermentans displays rhodoquinol-fumarate reductase activity.2003

    • Author(s)
      Miyadera, H., Hiraishi, A., Miyoshi, H., Sakamoto, K., Mineki, R., Murayama, K., Nagashima' V.P., Matsuura, K., Kojima, S., Kita, K
    • Journal Title

      Eur. J. Biochem. 270

      Pages: 1863-1874

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Parasite mitochondria as a drug target : diversity and dynamic changes during the life cycle2003

    • Author(s)
      Kita, K.
    • Journal Title

      Curr. Med. Chem. 10

      Pages: 1241-1253

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Role of complex II in anaerobic respiration of the parasite mitochondria from Ascaris suum and Plasmodium falciparum2002

    • Author(s)
      Kita, K.
    • Journal Title

      Biochim. Biophys. Acta 1553

      Pages: 123-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Electron transfer complexes in Ascaris mitochondria2002

    • Author(s)
      Kita, K., Takamiya, S.
    • Journal Title

      Advance in Parasitology. 51

      Pages: 95-131

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Role of complex II in anaerobic respiration of the parasite mitochondria from Ascaris suum and Plasmodium falciparum2002

    • Author(s)
      Kita, K., Hirawake, H., Miyadera, H., Amino, H., Takeo, S.
    • Journal Title

      Biochim. Biophys. Acta 1553

      Pages: 123-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Complex II inactivation is lethal in the nematode Caenorhabditis elegans2002

    • Author(s)
      Ichimiya, H., Huet, R.G., Hartman, P., Amino, H., Kita, K., Ishii, N.
    • Journal Title

      Mitochondrion 2

      Pages: 191-198

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Quinones in long- lived clk-1 mutants of Caenorhabditis elegans2002

    • Author(s)
      Miyadera, H., Kano, K., Miyoshi, H., Ishii, N., Hekimi, S., Kita, K.
    • Journal Title

      FEBS Lett. 512

      Pages: 33-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Electron transfer complexes in Ascaris mitochondria2002

    • Author(s)
      Kita, K.
    • Journal Title

      Advance in Parasitology 51

      Pages: 95-131

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans2001

    • Author(s)
      Miyadera, H., Amino, H., Hiraishi, A., Taka, H., Murayama, M., Miyoshi, H., Sakamoto, K., Ishii, N., Hekimi, S., Kita, K.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 7713-7716

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854011
  • [Journal Article] Parasitology in Japan: Advances in drug discovery and biochemical studies

    • Author(s)
      Kita, K., Shiomi, K., Omura, S
    • Journal Title

      Trends in Parasitol 23

      Pages: 223-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Journal Article] Mitochondrial DNA of parasites

    • Author(s)
      Kita, K, Watanabe, Y.
    • Journal Title

      Tanpakushitsu Kakusan koso (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590365
  • [Journal Article] Expression, purification, and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate

    • Author(s)
      Inaok, D.K., Takashima, E., Osanai, A., Shimizu, H., Nara, T., Aoki, T., (2005) Harada, S., Kita, K.
    • Journal Title

      Acta Crystallographica F61

      Pages: 875-878

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Parasite mitochondria as a target of chemotherapy : The inhibitory effect of licochalcone A on the Plasmodium fakiparum respiratory chain

    • Author(s)
      Mi-ichi, F., Miyadera, H., Kobayashi, T., Takamiya, S., Waki, S., Iwata, S.(2005) Shibata, S., Kita, K.
    • Journal Title

      Ann.New York Acad. Sci. 1056

      Pages: 46-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021014
  • [Journal Article] Ukulactones A and B, new NADH-fumarate reductase inhibitors produced by Penicillium sp.FKI-3389.

    • Author(s)
      Mori, M., Morimoto, H., Kim, Y-P., Ui, H., Nonaka, K., Masuma, R., Sakamoto, S., Kita, K., Tomoda, H., Shiomi, K., mura, S.
    • Journal Title

      Tetrahedron 掲載確定(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Patent] Dihydroorotic and acid dehydrogenase inhibitor2016

    • Inventor(s)
      Kiyoshi Kita, et al.
    • Industrial Property Rights Holder
      Kiyoshi Kita, et al.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-06-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Patent] Endoparasite control agent2016

    • Inventor(s)
      Kiyoshi Kita, et al.
    • Industrial Property Rights Holder
      Kiyoshi Kita, et al.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-10-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Patent] Endoparasite control agent and method for using the same2016

    • Inventor(s)
      Kiyoshi Kita, et al.
    • Industrial Property Rights Holder
      Kiyoshi Kita, et al.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-09-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Patent] 駆虫剤2014

    • Inventor(s)
      北 潔、稲岡 健ダニエル、山本 雅一
    • Industrial Property Rights Holder
      北 潔、稲岡 健ダニエル、山本 雅一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-10-17
    • Acquisition Date
      2015-04-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Patent] 内部寄生虫防除剤2011

    • Inventor(s)
      北潔、諏訪明之
    • Industrial Property Rights Holder
      東京大学、日本農薬株式会社
    • Industrial Property Number
      2011-045042
    • Filing Date
      2011-03-02
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] 寄生原虫 Trypanosoma 由来エネルギー代謝酵素を用いた代替エネルギ ー代謝経路の構築とミトコンドリア病研究への応用2021

    • Author(s)
      林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
    • Organizer
      日本生体エネルギー研究会第47回討論会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Co-crystal structure analysis of Ferulenol derivatives in complex with human dihydroorotate dehydrogenase: a therapeutic target for cancer cells living under tumor microenvironment2021

    • Author(s)
      Mohammed S. O. Tagod, Takaya Sakura, Eri Amalia, Takahiro Sasagawa, Osumi Yukiko, Matsui Hiroki, Masuda Ayuna, Yukiko Miyazaki, Tomoo Shiba, Hiroyuki Saimoto, Kiyoshi Kita, Daniel Ken Inaoka
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Biochemical studies of mitochondrial malate:quinone oxidoreductase from Toxoplasma gondii2021

    • Author(s)
      Acharjee R., Talaam K. K., Hartuti E. D., Matsuo Y., Sakura T., Gloria B. M., Hidano S., Kido Y., Mori M., Shiomi K., Sekijima M., Nozaki T., Umeda K., Nishikawa Y., Hamano S., Kita K. and Inaoka D. K.
    • Organizer
      日本生体エネルギー研究会第47回討論会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Expression of trypanosomal acetate: succinate CoA transferase is sufficient to develop resistance to the ATP synthase inhibitor bedaquiline in Mycobacterium smegmatis2021

    • Author(s)
      Bundutidi M. G, Ando Y., Matsuo Y., Nakatani Y., Kiel H., Cook G. M., Sakura T., Hamano S., Hirayama K. and Kita K., Inaoka D. K.
    • Organizer
      日本生体エネルギー研究会第47回討論会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 寄生原虫トリパノソーマ由来エネルギー代謝因子を用いたミトコンドリア呼吸鎖機能破綻の解析2021

    • Author(s)
      林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Characterization of putative sulfide:quinone oxidoreductase from an intestinal parasite Schistosoma mansoni2021

    • Author(s)
      Talaam Keith Kiplangat, Yuichi Matsuo, Acharjee Rajib, Tetsuo Yamashita, Kawano Tetsuro, Endah Dwi Hartuti, Tomoyoshi Nozaki, Shinjiro Hamano, Kiyoshi Kita, and Daniel Ken Inaoka
    • Organizer
      日本生体エネルギー研究会第47回討論会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Trypanosoma brucei由来シアン耐性酵素TAOのミトコンドリア病研究への応用2021

    • Author(s)
      林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
    • Organizer
      第九十回日本寄生虫学会・第三十二回日本臨床寄生虫学会・合同大会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] Trypanosoma 由来エネルギー代謝因子を用いたミトコンドリア病発症 機構の解明2020

    • Author(s)
      林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
    • Organizer
      日本生体エネルギー研究会 第46回討論会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 創薬標的としてのミトコンドリア-寄生虫からがん細胞まで-2019

    • Author(s)
      北潔
    • Organizer
      京都大学学際融合教育研究推進センター第9回生理化学ユニットシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] フィラリアのミトコンドリアを標的にした生化学的解析2019

    • Author(s)
      望月恒太、稲岡健ダニエル、Zannatul Ferdoush、大森惇子、福本晋也、濱﨑めぐみ、濱野真二郎、平山健二、北潔
    • Organizer
      第13回蠕虫研究会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] がん微小環境におけるピリミジン生合成経路2019

    • Author(s)
      稲岡健ダニエル, 宮崎幸子, 志波智夫, 斎本博之, Amalia Eri, 城戸康年, 坂井千香, Moore Anthony L., 原田繁春, 北潔
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 寄生虫はどうやって高濃度硫化水素環境に適応しているのか?2019

    • Author(s)
      稲岡健ダニエル、Talaam Keith Kiplangat、松尾祐一、川野哲郎、 Endah Dwi Hartuti、野崎智義、濱野真二郎、北潔
    • Organizer
      第13回蠕虫研究会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 薬剤ターゲットとしてのミトコンドリアー寄生虫からがん細胞までー2019

    • Author(s)
      北潔
    • Organizer
      日本臨床腫瘍薬学会学術大会2020
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 感染症の現状と課題、そして対策2019

    • Author(s)
      北潔
    • Organizer
      第7回アフリカ開発会議ポストフォーラムin 熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 肝蛭のミトコンドリア呼吸鎖におけるPlumbaginの作用機序の解明2019

    • Author(s)
      田渋敦士、関まどか、稲岡健ダニエル、麻田正仁、北潔
    • Organizer
      第13回蠕虫研究会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 回虫成虫複合体IIを標的にした特異的な抗線虫薬の創出2019

    • Author(s)
      志波智生, 稲岡健ダニエル, 北潔, 原田繁春
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03436
  • [Presentation] 競合および混合阻害剤との共結晶構造解析により明らかとなった出芽酵母由来Type II NADH脱水素酵素のユビキノン結合部位2018

    • Author(s)
      山下哲生,稲岡健ダニエル,志波智生,大橋匠,岩田想,矢木隆雄,三芳秀,原田繁春,北潔,平野勝也
    • Organizer
      日本農芸化学会中四国支部第51回講演会
    • Data Source
      KAKENHI-PROJECT-15K07005
  • [Presentation] Diversity of respiratory chains in parasite mitochondria - As a drug target -2017

    • Author(s)
      Kiyoshi Kita
    • Organizer
      the 115th International Titisee Conference
    • Place of Presentation
      Treschers Schwarzwaldhotel (Mainz, Germany)
    • Year and Date
      2017-03-29
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] NTDsと治療薬の現状と課題2017

    • Author(s)
      北 潔
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2017-03-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 薬剤標的としてのミトコンドリアー寄生虫からがん細胞までー2016

    • Author(s)
      北潔
    • Organizer
      日本農芸化学会2016年会
    • Place of Presentation
      札幌市
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] Magic Bullets for Parasitic Diseases - Drugs from Japan -2016

    • Author(s)
      KITA Kiyoshi
    • Organizer
      日本薬理学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] Ascofuranone: a gift from nature as anti-parasite drug2016

    • Author(s)
      KITA Kiyoshi
    • Organizer
      US-Japan EID Meeting - 50th Anniversary
    • Place of Presentation
      Bethesda, USA
    • Year and Date
      2016-01-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] Re-modeling of respiratory chain in the parasite mitochondria during their adaptation環境適応における寄生虫ミトコンドリア呼吸鎖のリモデリング2016

    • Author(s)
      北 潔
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県、つくば市)
    • Year and Date
      2016-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] Mitochondria as drug target -from parasites to cancer cells2016

    • Author(s)
      Kiyoshi Kita
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine, The 16th Conference of Japanese Society of Mitochondrial Research and Medicine
    • Place of Presentation
      TKPガーデンシティ品川(東京都、港区)
    • Year and Date
      2016-10-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] ミトコンドリア呼吸鎖電子伝達系 -創薬ターゲットとして-2016

    • Author(s)
      北 潔
    • Organizer
      日本生物工学会第23回九州支部飯塚大会
    • Place of Presentation
      九州工業大学(福岡県、飯塚市)
    • Year and Date
      2016-12-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 新規抗マラリア薬としての5-アミノレブリン酸2016

    • Author(s)
      北 潔
    • Organizer
      第6回ポルフィリン-ALA学会年会
    • Place of Presentation
      東京大学医科学研究所(東京都、港区)
    • Year and Date
      2016-04-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 熱帯感染症制圧へ向けての創薬 -薬剤標的としてのミトコンドリア-2016

    • Author(s)
      北 潔
    • Organizer
      中高温微生物研究センター・シンポジウム 「熱帯感染症の制圧に向けて」
    • Place of Presentation
      山口大学(山口県、山口市)
    • Year and Date
      2016-11-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] Ascofuranone: a gift from nature as anti-parasite drug2016

    • Author(s)
      Kiyoshi Kita
    • Organizer
      US-Japan EID Meeting - 50th Anniversary
    • Place of Presentation
      Rockville, MD, USA
    • Year and Date
      2016-01-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] 宿主内低酸素環境下で作動する寄生虫のエネルギー代謝経路鍵酵素の構造と特異的阻害剤2016

    • Author(s)
      原田繁春, 稲岡ダニエル健, バログン エマニュエル,佐藤暖, 志波智生, 北潔
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター/東北大学川内北キャンパス(宮城県)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] Echinococcus multilocularisミトコンドリアを標的とした創薬2016

    • Author(s)
      遠海重裕、稲岡健ダニエル、大森惇子、坂本君年、入江隆夫、孝口裕一、八木欣平、斎本博之、北潔
    • Organizer
      第85回日本寄生虫学会
    • Place of Presentation
      宮崎市
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] 新規抗エキノコックス薬の開発 -ミトコンドリアを標的として-2016

    • Author(s)
      北 潔
    • Organizer
      青海大学-宮崎大学合同シンポジウム -エキノコックス対策-
    • Place of Presentation
      中国青海大学畜牧獣医科学院 (青海省西寧市, 中国)
    • Year and Date
      2016-09-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 結晶構造から見たフルトラニルおよびその誘導体化合物の回虫成虫複合体Ⅱに対する特異性2015

    • Author(s)
      米愛加, 長濱まどか, 梅本亮, 山本京史, 佐藤暖, 志波智生, 稲岡 ダニエル健, 福田智美, 織田雅次, 北潔, 原田繁春
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 寄生線虫類のミトコンドリア酸呼吸と宿主内微小環境適応。2015

    • Author(s)
      稲岡ダニエル健, Ferdoush Zannatul, 大森淳子, 福田智美, 福本晋也, 福本真一郎, 志波智生, 原田繁春 , 北潔
    • Organizer
      第23回分子寄生虫学ワークショップ/ 第13回分子寄生虫・マラリア研究フォーラム合同大会
    • Place of Presentation
      帯広畜産大学
    • Year and Date
      2015-08-30
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 抗エキノコックス薬剤標的としてのミトコンドリアのフマル酸呼吸2015

    • Author(s)
      遠海重裕、稲岡 健ダニエル、大森惇子、坂本君年、入江陸夫、考口裕一、八木欣平、斎本博之、北潔
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 低酸素環境下で生息する回虫成虫複合体Ⅱの構造・機能相関と特異的阻害剤の開発2015

    • Author(s)
      原田繁春、稲岡 ダニエル健、北潔
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 原虫ミトコンドリオンの酢酸代謝2015

    • Author(s)
      稲岡ダニエル健、Emmanuel O. Balogun、鈴木重雄、志波智生、原田繁春、Frederic Bringaud、北潔
    • Organizer
      YoungMito 2015
    • Place of Presentation
      千葉・ホテルシーサイド一宮オーツカ
    • Year and Date
      2015-07-09
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 線虫類のフマル酸呼吸と宿主内微小環境適応2015

    • Author(s)
      Daniel Ken Inaoka , Zannatul Ferdoush, Ohmori Junko, Fukuda Tomomi, Shinya Fukumoto, Shinichiro Fukumoto, Shiba Tomoo, Harada Shigeharu and Kiyoshi Kita
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 犬糸状虫の生活環におけるミトコンドリア呼吸鎖の変動-成虫とミクロフィラリアの比較-2015

    • Author(s)
      Daniel Ken Inaoka, Zannatul Ferdoush, Ohmori Junko, Fukumoto Shinya, Shinichiro Fukumoto and Kiyoshi Kita
    • Organizer
      第9回蠕虫研究会
    • Place of Presentation
      岩手・つなぎ温泉 清温荘
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] 出芽酵母由来Type II NADH dehydrogenase (NDH-2)のユビキノン競合阻害剤との高分解能複合体構造解析2015

    • Author(s)
      大橋拓未、稲岡ダニエル健、山下哲生、志波智生、岩田想、原田繁春、北潔
    • Organizer
      日本生体エネルギー研究会 第41回討論会
    • Place of Presentation
      東京大学医学部1号館講堂
    • Year and Date
      2015-12-23
    • Data Source
      KAKENHI-PROJECT-15K07005
  • [Presentation] ミトコンドリア呼吸鎖の多様性:寄生虫からがん細胞まで2014

    • Author(s)
      北潔
    • Organizer
      第52回生物物理学会
    • Place of Presentation
      札幌市
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] 低酸素適応におけるミトコンドリアの役割:寄生虫からがん細胞まで2014

    • Author(s)
      北 潔
    • Organizer
      第14回日本ミトコンドリア学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 低酸素適応におけるミトコンドリアの役割:寄生虫からがん細胞まで2014

    • Author(s)
      北潔
    • Organizer
      第14回日本ミトコンドリア学会年会
    • Place of Presentation
      福岡市
    • Year and Date
      2014-12-04
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] ミトコンドリア呼吸鎖の多様性:寄生虫からがん細胞まで2014

    • Author(s)
      北 潔
    • Organizer
      第52回生物物理学会
    • Place of Presentation
      札幌
    • Year and Date
      2014-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 寄生虫の低酸素エネルギー代謝経路を標的にした構造生命科学による創薬2014

    • Author(s)
      原田繁春、北 潔
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-26253025
  • [Presentation] 寄生虫の低酸素エネルギー代謝経路を標的にした構造生命科学による創薬2014

    • Author(s)
      原田繁春、北潔
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都市
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] The different roles of mitochondrial complex II in the intraerythrocytic stages and insect stage of Plasmodium studied by gene targeting of the Fp subunit2012

    • Author(s)
      Kita, Kiyoshi
    • Organizer
      The Mantra Erskine Beach Resort
    • Place of Presentation
      Lorne(Australia)
    • Year and Date
      2012-02-22
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] The different roles of mitochondrial complex II in the intraerythrocytic stages and insect stage of Plasmodium studied by gene targeting of the Fp subunit2012

    • Author(s)
      北潔
    • Organizer
      MAM2012 Molecular Approaches to Malaria
    • Place of Presentation
      ローンMantra Erskine Resort(オーストラリア)
    • Year and Date
      2012-02-22
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] The roles of mitochondrial complex II(succinate-ubiquinone reductase/quinol-fumarate reductase) of Plasmodium studied by gene targeting of the Fp subunit2011

    • Author(s)
      Kita, Kiyoshi
    • Organizer
      Hotel Borobudur
    • Place of Presentation
      Jakarta(Indonesia)
    • Year and Date
      2011-11-08
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] 寄生虫ミトコンドリアの多様性:薬剤標的として2011

    • Author(s)
      北潔
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会館、京都府
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] Novel enzymes of parasite mitochondria essential for their survival2010

    • Author(s)
      Kita K.
    • Organizer
      The 10th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji (Hyogo)
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] エキノコックスミトコンドリア呼吸鎖複合体IIassembly factorのクローニング2010

    • Author(s)
      遠海重裕、坂元君年、後藤美穂、松本淳、八木欣平、片倉賢、奥祐三郎、藤田修、野崎智義、北潔
    • Organizer
      第70回日本寄生虫学会東日本支部大会
    • Year and Date
      2010-10-02
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] マラリア原虫コハク酸-ユビキノン還元(複合体II)の遺伝子破壊による表現型解析2009

    • Author(s)
      日野明紀菜、平井誠、田中健、松岡裕之、北潔
    • Organizer
      第78回日本寄生虫学会大会
    • Place of Presentation
      法政大学市ヶ谷キャンパス外濠校舎、東京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] 低酸素適応におけるミトコンドリアの役割2009

    • Author(s)
      北潔
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] 低酸素適応におけるミトコンドリアの役割2009

    • Author(s)
      北潔
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] 寄生性渦鞭毛藻類Perkinsusのミトコンドリアにおけるribosomal frameshiftを伴う遺伝子発現系2009

    • Author(s)
      増田功、松崎素道、北潔
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド、兵庫県
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] 寄生虫の生活環におけるダイナミックなエネルギー代謝の変動2008

    • Author(s)
      北潔
    • Organizer
      第81回日本生化学会大会第・31回日本分子生物学会年会合同大会
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] 寄生虫の生活環におけるダイナミックなエネルギー代謝の変動2008

    • Author(s)
      北潔
    • Organizer
      第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] 寄生虫の生活環におけるダイナミックなエネルギー代謝の変動2008

    • Author(s)
      北 潔
    • Organizer
      第81回日本生化学会大会第・31回日本分子生物学会年会合同大会
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] Ascaris suum quinol fumarate reductase can produce high amount of reactive oxygen species2008

    • Author(s)
      Madhavi Paranagama, Kimitoshi Sakamoto, Kiyoshi Kita
    • Organizer
      第81回日本生化学会大会第・31回日本分子生物学会年会合同大会
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] Ascaris suum quinol fumarate reductase can produce high amount of reactive oxygen species.2008

    • Author(s)
      Madhavi Paranagama, Kimitoshi Sakamoto, Kiyoshi Kita
    • Organizer
      第81回日本生化学会大会第・31回日本分子生物学会年会合同大会
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] Parasite mitochondria as a target of chemotherapy2007

    • Author(s)
      Kita K.
    • Organizer
      10th IUBMB Conference
    • Place of Presentation
      Salvador, Bahia, Brazil
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PLANNED-18073004
  • [Presentation] Diversity of parasite mitochondria: as a target of chemotherapy2007

    • Author(s)
      Kita, K
    • Organizer
      10 IUBMB Conference and 36a. Annual Meeting of SBBq
    • Place of Presentation
      Salvador, Brazil
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Presentation] Parasite mitochondria as a target of chemotherapy2007

    • Author(s)
      Kita, K
    • Organizer
      VIII Central American and Caribbean Congress of Parasitology and Tropical Medicine
    • Place of Presentation
      Habana, Cuba
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Presentation] Parasite mitochondria as a target of chemotherapy2007

    • Author(s)
      Kita K.
    • Organizer
      10th IUBMB Conference
    • Place of Presentation
      Salvador, Bahia, Brazil
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-18GS0314
  • [Presentation] Target of glycerol in ascofuranone/glycerol in vitro trypanocidal effect to African trvoanosomes2007

    • Author(s)
      Fujioka, S., Nakamura, K., Kido, Y., Sakamoto, K., Haga, Y., Saimoto, H., Suzuki, T., Yabu, Y., Kita, K
    • Organizer
      80th annual meeting of Biochemistry
    • Place of Presentation
      Japan
    • Year and Date
      2007-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390122
  • [Presentation] トリパノソーマ科原虫ミトコンドリアのATP合成における酢酸代謝の役割。

    • Author(s)
      稲岡ダニエル健、鈴木重雄、Emmanuel O. Balogun、原田繁春、Frédéric Bringaud、北潔
    • Organizer
      日本生体エネルギー研究会、第40回討論会
    • Place of Presentation
      愛媛大学 南加記念ホール
    • Year and Date
      2014-12-11 – 2014-12-13
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] ヒトミトコンドリアDHODHを標的とした分子創薬

    • Author(s)
      Daniel Ken Inaoka、Hiroyuki Saimoto 、Shigeharu Harada 、Kiyoshi Kita
    • Organizer
      第二回 YoungMito
    • Place of Presentation
      大阪府箕面・みのお山荘「風の杜」
    • Year and Date
      2014-05-22 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Chemical validation of 12-subunits respiratory Complex II from Trypanosomatid as drug target

    • Author(s)
      Daniel Ken Inaoka, Nozomu Nihashi, Chiaki Tsuge, Takeshi Nara, Shigeharu Harada, Kiyoshi Kita
    • Organizer
      13th International Congress of Parasitology
    • Place of Presentation
      Camino Real Hotel, Mexico City
    • Year and Date
      2014-08-10 – 2014-08-15
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Echinococcus multilocularis(larval stage)ミトコンドリアのフマル酸呼吸を薬剤標的とした新規薬剤開発

    • Author(s)
      遠海重裕、稲岡健ダニエル、大森惇子、坂本君年、入江隆夫、孝口裕一、八木欣平、斎本博之、北潔
    • Organizer
      第84回日本寄生虫学会大会
    • Place of Presentation
      杏林大学、三鷹市
    • Year and Date
      2015-03-21 – 2015-03-22
    • Data Source
      KAKENHI-PROJECT-26304041
  • [Presentation] Structure-based design of potent and selective inhibitors against Trypanosoma cruzi dihydroorotate dehydrogenase

    • Author(s)
      Daniel Ken Inaoka, Maiko Iida, Toshiyuki Tabuchi, 中15人、Kiyoshi Kita
    • Organizer
      The Asia Hub for e-Drug Discovery Symposium
    • Place of Presentation
      Chengdu, Sichuan, China
    • Year and Date
      2014-09-11 – 2014-09-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Dissociation constant (Kd) of Trypanosoma brucei alternative oxidase inhibitors and their trypanocidal activity

    • Author(s)
      Daniel Ken Inaoka, Tomoo Shiba, Tsuge Chiaki, Chou Rihe, Gen Takahashi, Satoshi Ueda, Yasutoshi Kido, Emmanuel Oluwadare Balogun, Kimitoshi Sakamoto, Takeshi Nara, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Hiroyuki Saimoto, Anthony Moore, Shigeharu Harada, Kiyoshi Kita
    • Organizer
      第84回日本寄生虫学会大会
    • Place of Presentation
      杏林大学三鷹キャンパス
    • Year and Date
      2015-03-21 – 2015-03-22
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] ブタ回虫、ヘモンカスとディロフィラリアの成虫及びアニサキスのL3幼虫では嫌気的なミトコンドリア呼吸鎖が機能する

    • Author(s)
      稲岡 ダニエル健、Zannatul Ferdoush、大森 惇子、福本 晋也、福本 奈津子、二橋 望、福本 真一郎、辻 尚利、北 潔
    • Organizer
      第8回蠕虫研究会
    • Place of Presentation
      ホテル鹿の湯 札幌定山渓
    • Year and Date
      2014-09-06 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Characterization of Eimeria tenella sporozoite mitochondria

    • Author(s)
      稲岡 ダニエル 健、松林 誠、小松谷 啓介、八田 岳士、三好 猛晴、磯部 尚、 川原 史也、山岸 潤也、彦坂 健児、佐藤 暖、志波 智生、原田 繁春、辻 尚利、北 潔
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Eimeria tenellaスポロゾイト呼吸鎖の生化学的解析

    • Author(s)
      稲岡 ダニエル 健、松林 誠、小松谷 啓介、八田 岳士、三好 猛晴、磯部 尚、川原 史也、山岸 潤也、彦坂 健児、佐藤 暖、志波 智生、 原田 繁春、辻 尚利、北 潔
    • Organizer
      第22回分子寄生虫学ワークショップ/第12回分子寄生虫・マラリア研究フォーラム合同大会
    • Place of Presentation
      帯広畜産大学・原虫病研究センター、PKホール
    • Year and Date
      2014-08-31 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Pyrimidine de novo biosynthesis under tumor microenvironment

    • Author(s)
      Daniel Ken Inaoka, Yukiko Hirota, Takahiro Sasagawa, Eriko Tomitsuka, Chika Sakai, Hiroyuki Saimoto, Shigeharu Harada, Kiyoshi Kita
    • Organizer
      第37回日本分子生物学会年会(ワークショップ)
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26870119
  • [Presentation] Eimeria tenella スポロゾイトのミトコンドリア精製法の確立と呼吸鎖酵素活性

    • Author(s)
      松林 誠、稲岡 ダニエル 健、小松谷 啓介、八田 岳士、三好 猛晴、磯部 尚、川原 史也、山岸 潤也、彦坂 健児、佐藤 暖、志波 智生、 原田 繁春、北 潔、辻 尚利
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学 高等教育推進機構
    • Year and Date
      2014-09-09 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-26870119
  • []

  • 1.  KOJIMA Somei (00009622)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  HARADA Shigeharu (80156504)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 22 results
  • 3.  MIYOSHI Hideto (20190829)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 4.  WATANABE Yoh-ichi (90323568)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 5.  AMINO Hisako (10323601)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 6.  SASAKAWA Chihiro (70114494)
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  • 9.  HORII Toshihiro (80142305)
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  • 16.  YANAGI Yusuke (40182365)
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  • 18.  KAWAMOTO Fumihiko (40115556)
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  • 19.  審良 静男 (50192919)
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  • 22.  MITSUYAMA Masao (10117260)
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  • 23.  NISHIYAMA Yukihiro (60115615)
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  • 27.  KIMURA Masatsugu (60195378)
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  • 28.  TAKAOKA Hiroyuki (00094152)
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  • 29.  FUKUDA Masako (00156788)
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  • 30.  KANBE Toshio (50093018)
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  • 31.  SATO Yasuaki (30533616)
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  • 32.  鳥居 本美 (20164072)
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  • 34.  HORIGUCHI Yasuhiko (00183939)
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  • 35.  KOYASU Shigeo (90153684)
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  • 36.  NAKANISHI Kenji (60172350)
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  • 37.  SASAKI Narie (20359699)
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  • 38.  Nonaka Nariaki (50281853)
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  • 39.  HORII Yoichiro (80173623)
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  • 40.  KOUGUCHI Hirokazu (50435567)
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  • 41.  HATTORI Shosaku (00164864)
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  • 42.  ITAI Akiko (60012647)
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  • 43.  MATSUDA Akira (90157313)
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  • 44.  SEKIMIZU Kazuhisa (90126095)
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  • 45.  TAKEO Satoru (40302666)
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  • 46.  MATSUMOOT Yoshitsugu (00173922)
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  • 47.  KANO Shigeyuki (60233912)
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  • 48.  ITO Mamoru (00176364)
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  • 49.  MAENO Yoshimasa (70131191)
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  • 50.  KURAMOCHI Toshiaki (80277590)
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  • 51.  MATSUOKA Hiroyuki (10173816)
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  • 52.  OTSUKA Yasushi (00244161)
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  • 53.  OHTSUKI Takashi (80321735)
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  • 54.  KAMIYA Haruo (70002079)
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  • 55.  YABU Yoshisada (70080083)
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  • 56.  SUZUKI Takashi (70305530)
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  • 57.  AOKI Takashi (20053283)
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  • 58.  TAKEI Yayoi (40197257)
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  • 59.  SAKAI Kikuko (70722023)
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  • 60.  SAITO Takashi (10532533)
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  • 61.  OTA Itaru (60191938)
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  • 62.  MOJI Kazuhiko (80166321)
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  • 63.  NISHI Makoto (10444473)
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  • 64.  HONMA Teruki (10466039)
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  • 66.  MIYATA Makoto (50209912)
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  • 67.  MORI Hiroyuki (10243271)
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  • 68.  UYEDA Q. Taro (90356551)
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  • 99.  NAGATA Kyosuke
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  • 105.  NI Ma
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  • 106.  ENKAI Shigehiro
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  • 107.  SUGIKI Akiko
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  • 108.  KAWAGUCHI Hiroko
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  • 109.  OGAWA Shingo
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  • 110.  NOYA Oscar
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  • 111.  NOYA Belkisy
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  • 112.  KAI Feng
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  • 113.  Hermann Feldmeier
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  • 114.  Edward Kirumira
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  • 115.  Kato Stonewall
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  • 116.  ACHARJEE RAJIB
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  • 117.  MATSUZAKI Motomichi
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    # of Collaborated Products: 1 results
  • 118.  NIIKURA Mamoru
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    # of Collaborated Products: 1 results
  • 119.  永宗 喜三郎
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    # of Collaborated Products: 1 results
  • 120.  井上 将行
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    # of Collaborated Products: 2 results
  • 121.  城戸 康年
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    # of Collaborated Products: 1 results
  • 122.  庄司 光男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 123.  平井 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 124.  山本 林
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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