Tsumoto Kouhei 津本浩平

… Alternative Names

TSUMOTO Kouhei 津本浩平

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Researcher Number	90271866
Other IDs
External Links
Affiliation (Current)	2025: 東京大学, 大学院工学系研究科(工学部), 教授 2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, 招へい副センター長
Affiliation (based on the past Project Information) *help	2016 – 2023: 東京大学, 大学院工学系研究科(工学部), 教授 2013 – 2017: 東京大学, 大学院工学系研究科, 教授 2013 – 2015: 東京大学, 工学(系)研究科(研究院), 教授 2014: 東京大学, 工学系研究科, 教授 2010 – 2012: 東京大学, 医科学研究所, 教授 … More 2007 – 2009: The University of Tokyo, Graduate School of Frontier Sciences, Associate Professor 2006: 東京大学, 大学院新領域創成科学研究科, 助教授 2006: The University of Tokyo, Graduate School of Frontier Sciences, Associate Professor, 新領域創成科学研究科, 助教授 2005: 東京大学, 大学院・新領域創成科学研究科, 助教授 2002 – 2004: 東北大学, 大学院・工学研究科, 助教授 2001: 東北大学, 大学院・工学研究科, 講師 1997 – 2000: 東北大学, 大学院・工学研究科, 助手 1996 – 1998: 東北大学, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Complex systems / Biofunction/Bioprocess / Biofunction/Bioprocess / Science and Engineering / Biophysics / Basic Section 27040:Biofunction and bioprocess engineering-related / 生物・生体工学 / Molecular biology Except Principal Investigator Science and Engineering / Biological Sciences … More / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 50:Oncology and related fields / Pathology, Infection/Immunology, and related fields / Chemical engineering and related fields / Otorhinolaryngology / Functional materials chemistry / 生物・生体工学 / Digestive surgery / Chemistry / Engineering / Biomolecular chemistry / Cell biology / Biofunction/Bioprocess / Science and Engineering Less
Keywords	Principal Investigator 蛋白質 / 分子認識 / 相互作用 / 特異性 / 物理化学 / 生物・生体工学 / 蛋白質間相互作用 / 抗体 / 熱力学 / バイオテクノロジー … More / 金属細胞生物学 / 生物無機化学 / 生命金属科学 / 生体分子 / 受容体 / 可溶化 / X線結晶構造解析 / 蛋白質工学 / 熱量測定 / ダイナミクス / 蛋白質エンジニアリング / 分子動力学計算 / 金属イオン / CDR / フラクチュエーション / ペプチド / 計算科学 / 抗原 / 低分子化合物 / 低分子化抗体 / 金属取り込み / 病原性微生物 / 生命物理化学 / モダリティ / 機能制御分子 / 生体内金属動態 / 有害金属 / 生命金属 / 遷移状態 / 薬学 / 創薬 / 速度論 / 阻害剤 / 低分子 / 蛋白質-蛋白質相互作用 / BIO-ENGINEERING / BIOMOLECULE / BIOTECHNOLOGY / PROTEIN / リフォールディング / プロテインマニピュレーション / 製剤 / フィロールディング / 凝集会合形成 / クロマトグラフィー / アルギニン / 溶媒・添加剤 / 低分子スクリーニング / フラグメントスクリーニング / 熱力学解析 / 低分子創薬 / スクリーニング / 天然変性 / ナノバイオ / シグナル伝達 / 生物物理 / 後退ライブラリー / MUC1 / 膜蛋白質 / 抗体ライブラリー / 癌免疫療法 / MUCI / ファージ提示法 / 融合蛋白質 / EGFR / ファージディスプレイ / がん細胞 / 細胞表面抗原 / 非共有結合 / 変異体 / 熱力学的解析 / 蛋白性抗原 / 抗原抗体相互作用 / ファージ提示系 / 進化工学 / 親和性 / 可変領域断片 / 抗原抗体反応 / 繊維状ファージ … More Except Principal Investigator 分子認識 / 抗体 / 抗原抗体相互作用 / バイオテクノロジー / 結晶構造解析 / X線結晶構造解析 / Prestin / GFP / SEA / グルコーストランスポーター / 高分子ミセル / 蛋白質 / タンパク質相互作用 / 抗体工学 / ファージ提示法 / 変異導入 / 蛋白質間相互作用 / 熱力学的解析 / 自然免疫 / 巻き戻し系 / 不溶性顆粒 / 構造解析 / 生体信号計測 / 機械学習 / ヘルスケアIoT / ウェアラブル / 電子デバイス / 核酸 / Glut / Glut 1/4 / トランスフェリン / リサイクリング / 核酸医薬 / Glucose transporter / トランスフェリンレセプター / LDL受容体 / ヘテロ核酸 / 神経変性疾患 / トランスフェリン受容体 / 血液脳関門 / 血液脳腫瘍関門 / ドラッグデリバリーシステム / がん免疫療法 / 膠芽腫 / mRNA / 免疫チェックポイント阻害剤 / 分子標的薬 / 分子間相互作用 / 菌種特異的増殖阻害剤 / 細菌感染症 / 機能阻害 / 単分子抗体 / 鉄取り込み / スクリーニング / 低分子化合物 / 増殖阻害薬 / ヘム鉄 / Shr / 鉄獲得系 / A群レンサ球菌 / ヒアルロン酸 / 再生医学 / バイオマテリアル / 医用化学工学 / リンクモジュール / 炎症 / TSG-6 / レクチン / ハイドロゲル / Isothermal titration calorimetry / Purification / Atomic force microscopy / Molecular motor / Protein / Otology / 膜タンパク質 / アメリカ / 国際研究者交流 / 等温滴定型カロリメトリー / パッチクランプ法 / 走査プローブ顕微鏡 / 生物物理 / 等温滴定カロリメトリー / 精製 / 原子間力顕微鏡 / 分子モータ / 耳科学 / AND Logic Gate / Azobenzene / Photochromic Molecule / Molecular Chaperon / Chaperonin / リフォールディング / GroEL / 光異性化 / 分子機械 / AND論理回路 / アゾベンゼン / フォトクロミック分子 / 分子シャペロン / シャペロニン / REFOLDING SYSTEM / MOLECULAR RECOGNITION / EXPRESSION SYSTEM / CRYTAL STRUCTURE / AUTOANTIGENS / MUTAGENESIS / PHAGE-DISPLAY SYSTEM / ANTIBODY / 非共有結合 / 変異体 / 蛋白性抗原 / 巻き戻しシステム / 発現系 / 自己抗原 / single chain Fv / MUSE 11 / MUC 1 / Bispecific antibody / Cholangiocarcinoma / Adoptive immunotherapy / CD_<28> / CD_3 / MVC1 / LAK細胞 / Bispecific抗体 / scFu / MUC-1 / 一本鎖抗体 / MUSE11 / MUC1 / バイスペシフィク抗体 / 胆管癌 / 養子免疫療法 / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / アルツハイマー病 / 脳-血液関門 / 遺伝子治療 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / siRNA / 血液脳関門（BBB） / 薬物送達システム / ポリアミノ酸 / ポリエチレングリコール / ブロック共重合体 / ナノバイオ / タンパク質 / 生物機能工学 / コンピュータシミュレーション / スプライシング / ヒストン / 血管内皮細胞 / オルタナティブスプライシング / パターン認識受容体 / 細胞周期 / RNAプロセッシング / ペントラキシン / ヒストン障害 / 敗血症 / がん化 / 糸球体 / 細胞間接着 / 細胞接着 / ダイニン / プロテオーム / 抗リン酸化抗体 / 細胞運動 / 細胞内情報伝達 / リン酸化 / MAPキナーゼ / ERK / ファージディスプレイ / Hot-Spot / 細胞表面抗原 / ナノ材料 / 非天然型抗体 / 生細胞パニング / 親和性成熟 / ヒトFc受容体 / 非天然型組換え抗体 / 二重特異性抗体 / diabody / マテリアル認識ペプチド / CDR移植 / 無作為変異導入 / 高機能性非天然型抗体 / 金表面特異的抗体 / 酸化亜鉛認識抗体 / マテリアル認識抗体 / ペプチド移植 / バイオインターフェイス / 相補性 / 熱力学 / 特異性・親和性 / 抗原 / ヒト白血球抗原 / T細胞受容体 / 細胞性免疫 / 受容体 / 等温滴定型熱量測定 / 表面プラズモン共鳴 / ILT-HLA相互作用 / TCR-HLA相互作用 / 卷き戻し系 / エリスロポエチン受容体 / 抗体-受容体キメラ蛋白質 / 融合蛋白質 / 細胞増殖 / キメラ受容体 Less

Full-body electronic skins for digital me
- Principal Investigator
  
  染谷隆夫
- Project Period (FY)
  2022 – 2028
- Research Category
  
  Fund for the Promotion of Joint International Research (International Leading Research )
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Elucidation and Control of Local Fractions in Protein EngineeringPrincipal Investigator
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  The University of Tokyo
Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemArea Organizer
- Area Organizer
  
  津本浩平
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemPrincipal Investigator
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Development of molecular recognition elements for understanding and regulation of biometal dynamicsPrincipal Investigator
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Pioneering glioblastoma therapy by in situ mRNA-based amplification of immune checkpoint inhibitors
- Principal Investigator
  
  Kataoka Kazunori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Development of novel in situ crosslinked hydrogel using lectins
- Principal Investigator
  
  Ito Taichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Chemical engineering and related fields
- Research Institution
  The University of Tokyo
Development of species-specific anti-bacterial therapeutic agents based on molecular interaction
- Principal Investigator
  
  NAKAGAWA ICHIRO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pathology, Infection/Immunology, and related fields
- Research Institution
  Kyoto University
Development of heteroduplex oligonucleotide crossing the blood-brain barrier
- Principal Investigator
  
  Yokota Takanori
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical and Dental University
Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approachesPrincipal Investigator
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Dynamics of Molecular Pattern Recognition in Protein Interaction
- Principal Investigator
  
  HAMAKUBO TAKAO
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Ligand discovery based on biophysical analysesPrincipal Investigator
- Principal Investigator
  
  Tsumoto Kouhei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  The University of Tokyo
Bio-design for interface molecules in nano scale
- Principal Investigator
  
  KUMAGAI IZUMI
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Engineering
- Research Institution
  Tohoku University
Analysis of regulatory mechanisms of newly identified ERK substrates
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
Structural and Functional Analyses of Intrinsically Unfolded Proteins for EngineeringPrincipal Investigator
- Principal Investigator
  
  TSUMOTO Kouhei
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
蛋白質相互作用における多重特異性の定量的記述と応用Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
受容体分子認識における多重特異性発現機構の定量的解明Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Structural and functional analysis of the motor protein prestin using purified protein
- Principal Investigator
  
  WADA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Tohoku University
Development of a novel system for solubilization and preparation of proteins based on the aggregation suppression effects of arginine on proteinsPrincipal Investigator
- Principal Investigator
  
  TSUMOTO Kouhei
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Fabrication of dynamic materials using molecular chaperons
- Principal Investigator
  
  KINBARA Kazushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional materials chemistry
- Research Institution
  The University of Tokyo
抗原抗体反応における特異性・親和性創出と水分子との関連に関する実験的考察
- Principal Investigator
  
  熊谷泉
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Protein Engineering for Construction of Bio-interfaces
- Principal Investigator
  
  KUMAGAI Izumi
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tohoku University
細胞表面抗原特異的ヒト抗体の網羅的選択・調製と応用Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  Tohoku University
構造情報に基づく細胞性免疫システムにおける特異的分子認識機構の解明
- Principal Investigator
  
  熊谷泉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
GENERATION AND UTILIZATION OF NOVEL HUMAN ANTIBODY MOLECULES BASED ON GENETIC INFORMATION
- Principal Investigator
  
  KUMAGAI Izumi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Tohoku University
構造情報に基づく抗原抗体反応の精密解析と特異性・親和性を決定する因子の抽出Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Tohoku University
シグナル伝達機構解析を目指した抗体-受容体キメラ蛋白質の創製と構造解析
- Principal Investigator
  
  熊谷泉
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
新機能抗体-受容体キメラ蛋白質の創製と細胞増殖制御機構解析への応用
- Principal Investigator
  
  KUMAGAI Izumi
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
抗体分子の人工設計を目指す抗原抗体相互作用の精密解析Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Tohoku University
Establishment of the adoptive anticancer immunotherapy for the unresectable cholangiocarcinoma using the bispecific antibody - Construction of bacterial expression system of bispecific antibodies
- Principal Investigator
  
  SUZUKI Masanori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY
新規なファージベクター系を利用した抗体分子の機能改変Principal Investigator
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University

[Book] 創薬研究のためのスクリーニング学実践テキスト2022
- Author(s)
  （分担）長門石曉，津本浩平、（編）スクリーニング学研究会
- Total Pages
  374
- Publisher
  羊土社
- ISBN
  9784758122580
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 医用工学ハンドブック2022
- Author(s)
  佐久間一郎、秋吉一成、津本浩平
- Total Pages
  544
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437350
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] 品質評価のカギをにぎる　バイオ医薬品の分析法2022
- Author(s)
  津本浩平、石井明子、内山進、本田真也
- Total Pages
  180
- Publisher
  じほう
- ISBN
  9784840754606
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 治療の可能性が広がる　抗体医薬2022
- Author(s)
  津本　浩平
- Total Pages
  231
- Publisher
  羊土社
- ISBN
  9784758104074
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 治療の可能性が広がる　抗体医薬2022
- Author(s)
  津本　浩平
- Total Pages
  231
- Publisher
  羊土社
- ISBN
  9784758104074
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] 医薬品開発のための分光法2022
- Author(s)
  津本浩平、長門石曉、半沢宏之
- Total Pages
  272
- Publisher
  講談社
- ISBN
  9784065295823
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 医用工学ハンドブック2022
- Author(s)
  佐久間一郎、秋吉一成、津本浩平
- Total Pages
  544
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437350
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 品質評価のカギをにぎる　バイオ医薬品の分析法2022
- Author(s)
  津本浩平、石井明子、内山進、本田真也
- Total Pages
  180
- Publisher
  じほう
- ISBN
  9784840754606
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] 医薬品開発のための分光法2022
- Author(s)
  津本浩平、長門石曉、半沢宏之
- Total Pages
  272
- Publisher
  講談社
- ISBN
  9784065295823
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] ヘムタンパク質の科学2022
- Author(s)
  （分担）中木戸誠，津本浩平、（監修）城宜嗣、青野重利、齋藤正男
- Total Pages
  472
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437787
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 創薬研究のための相互作用解析パーフェクト2021
- Author(s)
  津本　浩平、前仲　勝実
- Total Pages
  368
- Publisher
  羊土社
- ISBN
  9784758122566
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 生命金属ダイナミクス　～生体内における金属の挙動と制御～2021
- Author(s)
  城　宜嗣、津本　浩平
- Total Pages
  564
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] 生命金属ダイナミクス～生体内における金属の挙動と制御～2021
- Author(s)
  中木戸誠, 津本浩平
- Total Pages
  564
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437060
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 創薬研究のための相互作用解析パーフェクト2021
- Author(s)
  津本　浩平、前仲　勝実
- Total Pages
  368
- Publisher
  羊土社
- ISBN
  9784758122566
- Data Source
  KAKENHI-PLANNED-19H05766
[Book] 熱量測定・熱分析ハンドブック第3版2020
- Author(s)
  長門石曉, 津本浩平
- Total Pages
  363
- Publisher
  日本熱測定学会
- ISBN
  9784621305072
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 膜タンパク質工学ハンドブック2020
- Author(s)
  由井杏奈, 妹尾暁暢, 長門石曉, 津本浩平
- Total Pages
  624
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860435370
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 機器分析ハンドブック 2 高分子・分離分析編2020
- Author(s)
  中木戸誠, 長門石曉, 津本浩平
- Total Pages
  192
- Publisher
  化学同人
- ISBN
  9784759820225
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 第19章　抗体医薬の基礎物性評価医薬品原薬の結晶化と物性評価:その最先端技術と評価の実際2019
- Author(s)
  津本浩平, 長門石曉
- Total Pages
  10
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 材料創製を指向したタンパク質相互作用解析高分子, 68巻3月号2019
- Author(s)
  長門石曉, 中木戸誠, 津本浩平
- Total Pages
  2
- Publisher
  高分子学会
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 黄色ブドウ球菌の鉄取り込み機構：Isdシステム生化学, 90(3), 279-2892018
- Author(s)
  Jose M. M. Caaveiro, 津本浩平
- Total Pages
  11
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 薬学雑誌, 138(8), 1033-10412018
- Author(s)
  長門石曉, Jose M. M. Caaveiro, 津本浩平次世代の低分子創薬を拓くタンパク質-低分子間相互作用の物理化学的解析
- Total Pages
  9
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] タンパク質相互作用の創薬－物理化学を介して生体の科学, Vol.69, No.4, 349-3532018
- Author(s)
  長門石曉, 津本浩平
- Total Pages
  5
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 神経難病と抗体医薬による分子標的治療医薬ジャーナル　2018年7月号 Vol.54, No.7, 1607-16112018
- Author(s)
  中木戸誠, 津本浩平
- Total Pages
  5
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] バイオ医薬品の分析のコツ　品質評価のための基礎と応用（第７回）タンパク質の分子間相互作用 PHARM TECH JAPAN 2018年2月号 Vol.34 No.2, 339-3452018
- Author(s)
  津本浩平, 長門石曉, 中木戸誠, 黒田大祐
- Total Pages
  7
- Publisher
  株式会社じほう
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] コンピュータ技術による抗体分子設計実験医学 2018年7月 Vol.36, No.11, 1859-18662018
- Author(s)
  黒田大祐, 津本浩平
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] CSJカレントビュー　医療・診断・創薬の化学　医療応用のための物理化学2017
- Author(s)
  津本浩平、長門石曉（分担執筆）
- Total Pages
  6
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] 生体分子化学　8章　酵素2017
- Author(s)
  長門石曉、津本浩平（分担執筆）
- Total Pages
  27
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-16H02420
[Book] サイエンスシグナリングジャパン2015
- Author(s)
  太期　健二、津本　浩平、浜窪　隆雄
- Total Pages
  2
- Publisher
  米国科学振興協会
- Data Source
  KAKENHI-PROJECT-25220205
[Book] 実験医学研究成果を薬につなげるアカデミア創薬の戦略と実例：化合物の“質”を評価する新しいスクリーニング系2014
- Author(s)
  長門石曉、津本浩平
- Total Pages
  220
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25249115
[Book] 技術レポート２０２３：物理化学的スクリーニング技術による創薬戦略と展望2013
- Author(s)
  長門石曉、津本浩平
- Total Pages
  324
- Publisher
  日本能率協会総合研究所
- Data Source
  KAKENHI-PROJECT-25249115
[Book] 生化学事典「クロマトグラフィー」「界面活性剤」2012
- Author(s)
  中木戸誠、津本浩平
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 遺伝子工学2011
- Author(s)
  津本浩平
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 生物工学2011
- Author(s)
  津本浩平
- Data Source
  KAKENHI-PROJECT-21360398
[Book] Amino Acids, Peptides and Proteins in Organic Chemistry Volume 5-Analysis and Function of Amino Acids and Peptides2011
- Author(s)
  Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, Tsutomu Arakawa
- Publisher
  Wiley
- Data Source
  KAKENHI-PROJECT-21360398
[Book] BIOINDUSTRY2011
- Author(s)
  津本浩平
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 抗体の安定性向上技術2011
- Author(s)
  津本浩平
- Publisher
  BIOINDUSTRY
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 生化学事典2011
- Author(s)
  中木戸誠、津本浩平
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21360398
[Book] タンパク質相互作用解析:等温滴定型熱量測定と表面プラズモン共鳴2011
- Author(s)
  津本浩平
- Publisher
  生物工学
- Data Source
  KAKENHI-PROJECT-21360398
[Book] ファインケミカルシリーズ抗体医薬のための細胞構築と培養技術2010
- Author(s)
  津本浩平、江島大輔、荒川力
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 酵素:一般論「酵素利用技術大系」2010
- Author(s)
  津本浩平
- Publisher
  株式会社エヌ・ティーエス
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 酵素利用技術大系2010
- Author(s)
  津本浩平
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 抗原抗体相互作用の熱力学的制御生体機能関連化学部会ニュースレター2010
- Author(s)
  津本浩平
- Publisher
  社団法人日本化学会
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 抗体会合体の定量的評価の課題抗体医薬のための細胞構築と培養技術2010
- Author(s)
  津本浩平、江島大輔、荒川力
- Data Source
  KAKENHI-PROJECT-21360398
[Book] リフォールディング「酵素利用技術大系」2010
- Author(s)
  工藤基徳、津本浩平
- Publisher
  株式会社エヌ・ティーエス
- Data Source
  KAKENHI-PROJECT-21360398
[Book] Encyclopedia of Life Sciences2010
- Author(s)
  Kumagai I. and Tsumoto K.
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 薬学雑誌2009
- Author(s)
  津本浩平、宇井美穂子
- Data Source
  KAKENHI-PROJECT-21360398
[Book] 熱測定2009
- Author(s)
  津本浩平、宇井美穂子
- Data Source
  KAKENHI-PROJECT-21360398
[Book] たんぱく質結晶の新展開2008
- Author(s)
  津本、田中
- Publisher
  シーエムシー出版(印刷中)
- Data Source
  KAKENHI-PROJECT-19021011
[Book] たんぱく質結晶の新展開2008
- Author(s)
  津本、田中
- Total Pages
  15
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Book] たんぱく質結晶の新展開2008
- Author(s)
  津本, 田中
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-17360393
[Book] ナノバイオ辞典2007
- Author(s)
  津本浩平 (分担執筆)
- Total Pages
  1000
- Publisher
  エヌティーエス
- Data Source
  KAKENHI-PROJECT-17360393
[Book] ナノバイオ辞典2007
- Author(s)
  津本浩平(分担執筆)
- Total Pages
  1000
- Publisher
  エヌティーエス
- Data Source
  KAKENHI-PROJECT-18038007
[Book] バイオプロダクション2006
- Author(s)
  津本浩平
- Total Pages
  250
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17360393
[Book] バイオプロダクション2006
- Author(s)
  津本浩平(分担執筆)
- Total Pages
  180
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17360393
[Book] 生物物理学ハンドブック(分担執筆)2006
- Author(s)
  津本浩平
- Total Pages
  500
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-17360393
[Book] バイオプロダクション2006
- Author(s)
  津本
- Total Pages
  20
- Publisher
  コロナ社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Book] 生物物理学ハンドブック2006
- Author(s)
  津本, ら
- Total Pages
  4
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Book] ナノバイオ辞典2006
- Author(s)
  津本
- Total Pages
  2
- Publisher
  テクノシステム
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Book] 生物物理学ハンドブック(分担執筆)2006
- Author(s)
  津本浩平
- Total Pages
  500
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-18038007
[Book] バイオプロダクション2006
- Author(s)
  津本浩平(分担執筆)
- Total Pages
  180
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-18038007
[Book] ゲノミクス・プロテオミクスの新展開~生物情報の解析と応用~2005
- Author(s)
  津本
- Total Pages
  10
- Publisher
  エヌ・ティー・エス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Book] コンビナトリアルバイオエンジニアリングの展開 (担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
- Author(s)
  津本浩平ら
- Publisher
  CMC社(印刷中)
- Data Source
  KAKENHI-PROJECT-16041204
[Book] コンビナトリアルバイオエンジニアリングの展開 (担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
- Author(s)
  津本浩平ら
- Publisher
  CMC社(印刷中)
- Data Source
  KAKENHI-PROJECT-14704006
[Book] コンビナトリアルバイオエンジニアリングの展開(担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
- Author(s)
  津本浩平ら
- Publisher
  CMC社(印刷中)
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Experimental modification in thermal stability of oligomers by alanine substitution and site saturation mutagenesis of interfacial residues2024
- Author(s)
  Hoya Megumi、Matsunaga Ryo、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 691 Pages: 149316-149316
- DOI
  10.1016/j.bbrc.2023.149316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Structural basis for the recognition of human hemoglobin by the heme-acquisition protein Shr from Streptococcus pyogenes2024
- Author(s)
  Senoo Akinobu、Hoshino Masato、Shiomi Toshiki、Nakakido Makoto、Nagatoishi Satoru、Kuroda Daisuke、Nakagawa Ichiro、Tame Jeremy R. H.、Caaveiro Jose M. M.、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 5374-5374
- DOI
  10.1038/s41598-024-55734-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Functional insights of Tyr37 in framework region 2 directly contributing to the binding affinities and dissociation kinetics in single-domain VHH antibodies2024
- Author(s)
  Yamamoto Koichi、Nagatoishi Satoru、Nakakido Makoto、Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 709 Pages: 149839-149839
- DOI
  10.1016/j.bbrc.2024.149839
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Unveiling the affinity?stability relationship in anti-measles virus antibodies: a computational approach for hotspots prediction2024
- Author(s)
  Paul Rimpa、Kasahara Keisuke、Sasaki Jiei、P?rez Jorge Fern?ndez、Matsunaga Ryo、Hashiguchi Takao、Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 10 Pages: 1302737-1302737
- DOI
  10.3389/fmolb.2023.1302737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20596, KAKENHI-PLANNED-19H05766
[Journal Article] Generation of antibodies to an extracellular region of the transporters Glut1/Glut4 by immunization with a designed antigen2024
- Author(s)
  Sumikawa Taichi、Nakakido Makoto、Matsunaga Ryo、Kuroda Daisuke、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 2 Pages: 105640-105640
- DOI
  10.1016/j.jbc.2024.105640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PLANNED-21H05090
[Journal Article] High-throughput analysis system of interaction kinetics for data-driven antibody design2023
- Author(s)
  Matsunaga Ryo、Ujiie Kan、Inagaki Mayuko、Fern?ndez P?rez Jorge、Yasuda Yoshiki、Mimasu Shinya、Soga Shinji、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-023-46756-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ1171, KAKENHI-PLANNED-19H05766
[Journal Article] Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion2023
- Author(s)
  Senoo Akinobu、Nagatoishi Satoru、Kuroda Daisuke、Ito Sho、Ueno Go、Caaveiro Jose M. M.、Tsumoto Kouhei
- Journal Title
  
  Protein Science
  
  Volume: 32 Issue: 9
- DOI
  10.1002/pro.4744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] 生命金属科学：これまでも，これからも2023
- Author(s)
  津本浩平
- Journal Title
  
  Farumashia
  
  Volume: 59 Issue: 3 Pages: 171-171
- DOI
  10.14894/faruawpsj.59.3_171
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-19H05760
[Journal Article] Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes2023
- Author(s)
  Yamazaki Taichi、Nagatoishi Satoru、Yamawaki Tsukushi、Nozawa Takashi、Matsunaga Ryo、Nakakido Makoto、Caaveiro Jose M.M.、Nakagawa Ichiro、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 10 Pages: 105254-105254
- DOI
  10.1016/j.jbc.2023.105254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18214, KAKENHI-PROJECT-22KK0096, KAKENHI-PROJECT-21K07023, KAKENHI-PLANNED-19H05766, KAKENHI-PUBLICLY-22H04809, KAKENHI-PROJECT-23K24130
[Journal Article] Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain2023
- Author(s)
  Amano A, Sanjo N, Araki W, Anraku Y, Nakakido M, Matsubara E, Tomiyama T, Nagata T, Tsumoto K, Kataoka K, Yokota T.
- Journal Title
  
  J Nanobiotechnology
  
  Volume: 21 Issue: 1 Pages: 36-50
- DOI
  10.1186/s12951-023-01772-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19510, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-21K18268, KAKENHI-PROJECT-20K07798
[Journal Article] Structural insights into 3Fe?4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P4502023
- Author(s)
  Gilep A、Varaksa T、Bukhdruker S、Kavaleuski A、Ryzhykau Y、Smolskaya S、Sushko Ta、Tsumoto K、Grabovec I、Kapranov I、Okhrimenko I、Marin E、Shevtsov M、Mishin A、Kovalev K、Kuklin A、Gordeliy V、Kaluzhskiy L、Gnedenko O、Yablokov E、Ivanov A、Borshchevskiy V、Strushkevich N
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 9 Pages: 1100032-1100032
- DOI
  10.3389/fmolb.2022.1100032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Dispersion function of a protein, DP-1, identified in Collimonas sp. D-25, for the synthesis of gold nanoparticles2023
- Author(s)
  Tang Donglin、Kato Yugo、Zhang Dingkun、Negishi Lumi、Kurumizaka Hitoshi、Hirata Takafumi、Nakakido Makoto、Tsumoto Kouhei、Shuji Fujisawa、Tsuguyuki Saito、Okumura Taiga、Nagata Koji、Suzuki Michio
- Journal Title
  
  ChemBioChem
  
  Volume: 24 Issue: 14
- DOI
  10.1002/cbic.202300221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17888, KAKENHI-PROJECT-23K22611, KAKENHI-PLANNED-19H05766
[Journal Article] Design of single-domain VHH antibodies to increase the binding activity in SPR amine coupling2023
- Author(s)
  Hirao Atsunori、Nagatoishi Satoru、Ikeuchi Emina、Yamawaki Tsukushi、Mori Chinatsu、Nakakido Makoto、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 663 Pages: 54-60
- DOI
  10.1016/j.bbrc.2023.04.048
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Non-Affinity Purification of Antibodies2023
- Author(s)
  Arakawa Tsutomu、Tomioka Yui、Nakagawa Masataka、Sakuma Chiaki、Kurosawa Yasunori、Ejima Daisuke、Tsumoto Kouhei、Akuta Teruo
- Journal Title
  
  Antibodies
  
  Volume: 12 Issue: 1 Pages: 15-15
- DOI
  10.3390/antib12010015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Inactivation and spike protein denaturation of novel coronavirus variants by CuxO/TiO2 nano-photocatalysts2023
- Author(s)
  Tatsuma Tetsu、Nakakido Makoto、Ichinohe Takeshi、Kuroiwa Yoshinori、Tomioka Kengo、Liu Chang、Miyamae Nobuhiro、Onuki Tatsuya、Tsumoto Kouhei、Hashimoto Kazuhito、Wakihara Toru
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4033-4033
- DOI
  10.1038/s41598-023-30690-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03491
[Journal Article] In vitro validation of chromogenic substrate assay for evaluation of surrogate FVIII-activity of emicizumab2023
- Author(s)
  Yamaguchi Tomoko、Shinozawa Keiko、Nagatoishi Satoru、Mitsuhashi Ayano、Bingo Masato、Inaba Hiroshi、Amano Kagehiro、Tsumoto Kohei、Kinai Ei
- Journal Title
  
  Thrombosis Research
  
  Volume: 222 Pages: 131-139
- DOI
  10.1016/j.thromres.2023.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Quantitative analysis of antibody aggregates by combination of pinched-flow fractionation and coulter method2023
- Author(s)
  Nagatoishi Satoru、Toyoshima Toshinobu、Furukawa Kotohiro、Tsumoto Kouhei
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 681 Pages: 115331-115331
- DOI
  10.1016/j.ab.2023.115331
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Arginine cluster introduction on framework region in anti‐lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops2023
- Author(s)
  Maeta Shingo、Nakakido Makoto、Matsuura Hiroaki、Sakai Naoki、Hirata Kunio、Kuroda Daisuke、Fukunaga Atsushi、Tsumoto Kouhei
- Journal Title
  
  Protein Science
  
  Volume: 32 Issue: 9
- DOI
  10.1002/pro.4745
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PLANNED-21H05090
[Journal Article] Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene2023
- Author(s)
  Yui Anna、Kuroda Daisuke、Maruno Takahiro、Nakakido Makoto、Nagatoishi Satoru、Uchiyama Susumu、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 6493-6493
- DOI
  10.1038/s41598-023-32444-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Conformational features and interaction mechanisms of VH H antibodies with β-hairpin CDR3: A case of Nb8-HigB2 interaction2023
- Author(s)
  Yamamoto Koichi、Nagatoishi Satoru、Matsunaga Ryo、Nakakido Makoto、Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  Protein Science
  
  Volume: 32 Issue: 12
- DOI
  10.1002/pro.4827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Agarose native gel electrophoresis analysis of thermal aggregation controlled by Hofmeister series2023
- Author(s)
  Tomioka Yui、Sato Ryo、Takahashi Ryo、Nagatoishi Satoru、Shiba Kohei、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
- Journal Title
  
  Biophysical Chemistry
  
  Volume: 296 Pages: 106977-106977
- DOI
  10.1016/j.bpc.2023.106977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth2023
- Author(s)
  Valenciano-Bellido Sandra、Caaveiro Jose M.M.、Nakakido Makoto、Kuroda Daisuke、Aikawa Chihiro、Nakagawa Ichiro、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 9 Pages: 104927-104927
- DOI
  10.1016/j.jbc.2023.104927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18214, KAKENHI-PROJECT-22KK0096, KAKENHI-PLANNED-19H05766, KAKENHI-PUBLICLY-22H04809, KAKENHI-PROJECT-23K24130
[Journal Article] Biophysical insight into protein-protein interactions in the Interleukin-11/Interleukin-11Rα/glycoprotein 130 signaling complex2023
- Author(s)
  Mori Chinatsu、Nagatoishi Satoru、Matsunaga Ryo、Kuroda Daisuke、Nakakido Makoto、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 682 Pages: 174-179
- DOI
  10.1016/j.bbrc.2023.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Group A Streptococcus cation diffusion facilitator proteins contribute to immune evasion by regulating intracellular metal concentrations2023
- Author(s)
  Aikawa Chihiro、Shimizu Akihide、Nakakido Makoto、Murase Kazunori、Nozawa Takashi、Tsumoto Kouhei、Nakagawa Ichiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 676 Pages: 141-148
- DOI
  10.1016/j.bbrc.2023.07.052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18214, KAKENHI-PROJECT-22KK0096, KAKENHI-PROJECT-22K07053, KAKENHI-PROJECT-21K07023, KAKENHI-PLANNED-19H05766, KAKENHI-PUBLICLY-22H04809, KAKENHI-PROJECT-23K24130
[Journal Article] Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection2023
- Author(s)
  Akiba Hiroki、Fujita Junso、Ise Tomoko、Nishiyama Kentaro、Miyata Tomoko、Kato Takayuki、Namba Keiichi、Ohno Hiroaki、Kamada Haruhiko、Nagata Satoshi、Tsumoto Kouhei
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 987-987
- DOI
  10.1038/s42003-023-05326-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06453, KAKENHI-PLANNED-19H05766
[Journal Article] Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein2022
- Author(s)
  Otsubo Ryota、Minamitani Takeharu、Kobiyama Kouji、Fujita Junso、Ito Toshihiro、Ueno Shiori、Anzai Itsuki、Tanino Hiroki、Aoyama Hiroshi、Matsuura Yoshiharu、Namba Keiichi、Imadome Ken-Ichi、Ishii Ken J.、Tsumoto Kouhei、Kamitani Wataru、Yasui Teruhito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20120-20120
- DOI
  10.1038/s41598-022-24730-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15042, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K22630, KAKENHI-PROJECT-23K23821
[Journal Article] Residue-based program of a β-peptoid twisted strand shape via a cyclopentane constraint2022
- Author(s)
  Kim J, Kobayashi H, Yokomine M, Shiratori Y, Ueda T, Takeuchi K, Umezawa K, Kuroda D, Tsumoto K, Morimoto J, Sando S.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 20 Issue: 35 Pages: 6994-7000
- DOI
  10.1039/d2ob01300b
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20H03378
[Journal Article] Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations2022
- Author(s)
  Yasuda Satoshi、Akiyama Tomoki、Kojima Keiichi、Ueta Tetsuya、Hayashi Tomohiko、Ogasawara Satoshi、Nagatoishi Satoru、Tsumoto Kouhei、Kunishima Naoki、Sudo Yuki、Kinoshita Masahiro、Murata Takeshi
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 126 Issue: 5 Pages: 1004-1015
- DOI
  10.1021/acs.jpcb.1c08684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K14674, KAKENHI-PLANNED-18H05425, KAKENHI-PUBLICLY-21H00404, KAKENHI-PROJECT-21H02446, KAKENHI-PROJECT-20K21482, KAKENHI-PROJECT-21K15054, KAKENHI-PROJECT-20H02531
[Journal Article] Analysis of bovine serum albumin unfolding in the absence and presence of ATP by SYPRO Orange staining of agarose native gel electrophoresis2022
- Author(s)
  Tomioka Yui、Nakagawa Masataka、Sakuma Chiaki、Kurosawa Yasunori、Nagatoishi Satoru、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 654 Pages: 114817-114817
- DOI
  10.1016/j.ab.2022.114817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus.2022
- Author(s)
  Valenciano-Bellido Sandra、Caaveiro Jose M.M.、Morante Koldo、Sushko Tatyana、Nakakido Makoto、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Issue: 6 Pages: 101995-101995
- DOI
  10.1016/j.jbc.2022.101995
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-18H05425
[Journal Article] Experimental Comparison of Bond Lifetime and Viscoelastic Relaxation in Transient Networks with Well-Controlled Structures2022
- Author(s)
  Katashima Takuya、Kudo Ryota、Naito Mitsuru、Nagatoishi Satoru、Miyata Kanjiro、Chung Ung-il、Tsumoto Kouhei、Sakai Takamasa
- Journal Title
  
  ACS Macro Letters
  
  Volume: 11 Issue: 6 Pages: 753-759
- DOI
  10.1021/acsmacrolett.2c00152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05733, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K15338
[Journal Article] Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer2022
- Author(s)
  Shozu Kanto、Kaneko Syuzo、Shinkai Norio、Dozen Ai、Kosuge Hirofumi、Nakakido Makoto、Machino Hidenori、Takasawa Ken、Asada Ken、Komatsu Masaaki、Tsumoto Kouhei、Ohnuma Shin-Ichi、Hamamoto Ryuji
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 14 Issue: 1 Pages: 1-13
- DOI
  10.1186/s13148-022-01370-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-22KJ0925
[Journal Article] Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions2022
- Author(s)
  Shinozaki Chinatsu、Kohno Keita、Shiroishi Mitsunori、Takahashi Daisuke、Yoshikawa Yu、Abe Yoshito、Hamase Kenji、Nakakido Makoto、Tsumoto Kohei、Inoue Kazuhide、Tsuda Makoto、Ueda Tadashi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 131-131
- DOI
  10.1038/s41598-021-03784-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06514, KAKENHI-PROJECT-21K06517, KAKENHI-PROJECT-20H02531
[Journal Article] Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer2022
- Author(s)
  Suganuma Masatoshi、Kubo Takuya、Ishiki Kengo、Tanaka Kota、Suto Kouzou、Ejima Daisuke、Toyota Masahiro、Tsumoto Kouhei、Sato Toshiyuki、Nishikawa Youichi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 9568-9568
- DOI
  10.1038/s41598-022-13763-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] PRELP Regulates Cell-Cell Adhesion and EMT and Inhibits Retinoblastoma Progression2022
- Author(s)
  Hopkins Jack、Asada Ken、Leung Alex、Papadaki Vasiliki、Davaapil Hongorzul、Morrison Matthew、Orita Tomoko、Sekido Ryohei、Kosuge Hirofumi、Reddy M. Ashwin、Kimura Kazuhiro、Mitani Akihisa、Tsumoto Kouhei、Hamamoto Ryuji、Sagoo Mandeep S.、Ohnuma Shin-ichi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 19 Pages: 4926-4926
- DOI
  10.3390/cancers14194926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-22KJ0925, KAKENHI-PROJECT-20K09805
[Journal Article] Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics2022
- Author(s)
  Khetan R, Curtis R, Deane CM, Hadsund JT, Kar U, Krawczyk K, Kuroda D, Robinson SA, Sormanni P, Tsumoto K, Warwicker J, Martin ACR.
- Journal Title
  
  mAbs
  
  Volume: 14 Issue: 1 Pages: 2020082-2020082
- DOI
  10.1080/19420862.2021.2020082
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19H04202
[Journal Article] Nucleic acid-triggered tumoral immunity propagates pH‐selective therapeutic antibodies through tumor‐driven epitope spreading2022
- Author(s)
  Furuya G, Katoh H, Atsumi S, Hashimoto I, Komura D, Hatanaka R, Senga S, Hayashi S, Akita S, Matsumura H, Miura A, Mita H, Nakakido M, Nagatoishi S, Sugiyama A, Suzuki R, Konishi H, Yamamoto A, Abe H, Hiraoka N, Aoki K, Kato Y, Seto Y, Yoshimura C, Miyadera K, Tsumoto K, Ushiku T, Ishikawa S
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 1 Pages: 321-338
- DOI
  10.1111/cas.15596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10074, KAKENHI-PROJECT-22K09929, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-20H02531
[Journal Article] Development of a high-throughput method to screen novel antiviral materials2022
- Author(s)
  Nakakido Makoto、Tanaka Naoki、Shimojo Ayako、Miyamae Nobuhiro、Tsumoto Kouhei
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 4 Pages: e0266474-e0266474
- DOI
  10.1371/journal.pone.0266474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Analytical Method for Experimental Validation of Computer-Designed Antibody2022
- Author(s)
  Tanabe Aki、Tsumoto Kouhei
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2552 Pages: 409-433
- DOI
  10.1007/978-1-0716-2609-2_23
- ISBN
  9781071626085, 9781071626092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-22K15598
[Journal Article] Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction2022
- Author(s)
  Kosuge Hirofumi、Nagatoishi Satoru、Kiyoshi Masato、Ishii-Watabe Akiko、Terao Yosuke、Ide Teruhiko、Tsumoto Kouhei
- Journal Title
  
  Biochemistry
  
  Volume: 62 Issue: 2 Pages: 262-269
- DOI
  10.1021/acs.biochem.1c00832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-22KJ0925, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-19H05766
[Journal Article] Addition of arginine hydrochloride and proline to the culture medium enhances recombinant protein expression in Brevibacillus choshinensis: The case of RBD of SARS-CoV-2 spike protein and its antibody2022
- Author(s)
  Matsunaga Ryo、Tsumoto Kouhei
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 194 Pages: 106075-106075
- DOI
  10.1016/j.pep.2022.106075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K14737, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Performance Comparison of Spectral Distance Calculation Methods2022
- Author(s)
  Oyama Taiji、Suzuki Satoko、Horiguchi Yasuo、Yamane Ai、Akao Kenichi、Nagamori Koushi、Tsumoto Kouhei
- Journal Title
  
  Applied Spectroscopy
  
  Volume: 76 Issue: 12 Pages: 1482-1493
- DOI
  10.1177/00037028221121687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Ladder observation of bovine serum albumin by high resolution agarose native gel electrophoresis2022
- Author(s)
  Tomioka Yui、Nakagawa Masataka、Sakuma Chiaki、Nagatoishi Satoru、Tsumoto Kouhei、Arakawa Tsutomu、Akuta Teruo
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 215 Pages: 512-520
- DOI
  10.1016/j.ijbiomac.2022.06.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Correction: Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masaneori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 8 Pages: 102262-102262
- DOI
  10.1016/j.jbc.2022.102262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15598, KAKENHI-PROJECT-20H02531
[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masanori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Issue: 6 Pages: 101962-101962
- DOI
  10.1016/j.jbc.2022.101962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-21K08272, KAKENHI-PLANNED-21H05090, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03228
[Journal Article] Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR32022
- Author(s)
  Kinoshita Seisho、Nakakido Makoto、Mori Chinatsu、Kuroda Daisuke、Caaveiro Jose M.M.、Tsumoto Kouhei
- Journal Title
  
  Protein Science
  
  Volume: 31 Issue: 11 Pages: 1-12
- DOI
  10.1002/pro.4450
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05090, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03228, KAKENHI-PLANNED-19H05766
[Journal Article] Structural Classification of CDR-H3 in Single-Domain VHH Antibodies2022
- Author(s)
  Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2552 Pages: 61-79
- DOI
  10.1007/978-1-0716-2609-2_2
- ISBN
  9781071626085, 9781071626092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Production of IgG1-based bispecific antibody without extra cysteine residue via intein-mediated protein trans-splicing2021
- Author(s)
  Akiba Hiroki、Ise Tomoko、Nagata Satoshi、Kamada Haruhiko、Ohno Hiroaki、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 19411-19411
- DOI
  10.1038/s41598-021-98855-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Molecular basis for the activation of actinoporins by lipids2021
- Author(s)
  Caaveiro Jose M.M.、Tsumoto Kouhei
- Journal Title
  
  Methods Enzymol.
  
  Volume: 649 Pages: 277-306
- DOI
  10.1016/bs.mie.2021.01.008
- ISBN
  9780128238585
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Single-chain variable fragment (scFv) targeting streptolysin O controls group A Streptococcus infection.2021
- Author(s)
  Aikawa C, Kawashima K, Fukuzaki C, Nakakido M, Murase K, Nozawa T, Tsumoto K, Nakagawa I
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 20 Pages: 177-183
- DOI
  10.1016/j.bbrc.2021.06.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07537, KAKENHI-PROJECT-18KK0193, KAKENHI-PUBLICLY-20H05504, KAKENHI-PROJECT-19H03471, KAKENHI-PROJECT-21K07023, KAKENHI-PROJECT-21K19376, KAKENHI-PROJECT-20H02531
[Journal Article] An integrated computational pipeline for designing high-affinity nanobodies with expanded genetic codes2021
- Author(s)
  Aditya K Padhi, Ashutosh Kumar, Ken-ichi Haruna, Haruna Sato, Hiroko Tamura, Satoru Nagatoishi, Kouhei Tsumoto, Atushi Yamaguchi, Fumie Iraha, Mihoko Takahashi, Kensaku Sakamoto, Kam Y J Zhang
- Journal Title
  
  Briefings in Bioinformatics
  
  Volume: 22 Issue: 6
- DOI
  10.1093/bib/bbab338
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02416, KAKENHI-PROJECT-20H02531
[Journal Article] Structural basis for antigen recognition by methylated lysine?specific antibodies2021
- Author(s)
  Ishii M, Nakakido M, Caaveiro JMM, Kuroda D, Okumura CJ, Maruyama T, Entzminger K, Tsumoto K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100176-100176
- DOI
  10.1074/jbc.ra120.015996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-17H06109
[Journal Article] Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope2021
- Author(s)
  Makabe Koki、Yokoyama Takeshi、Uehara Shiro、Uchikubo-Kamo Tomomi、Shirouzu Mikako、Kimura Kouki、Tsumoto Kouhei、Asano Ryutaro、Tanaka Yoshikazu、Kumagai Izumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5790-5790
- DOI
  10.1038/s41598-021-84171-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0178, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19H02519, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H02534, KAKENHI-PROJECT-19H02831, KAKENHI-PROJECT-19H00918
[Journal Article] Novel neutralizing human monoclonal antibodies against tetanus neurotoxin2021
- Author(s)
  Minamitani Takeharu、Kiyose Karin、Otsubo Ryota、Ito Toshihiro、Akiba Hiroki、Furuta Rika A.、Inoue Tsuyoshi、Tsumoto Kouhei、Satake Masahiro、Yasui Teruhito
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 12134-12134
- DOI
  10.1038/s41598-021-91597-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16641, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K16403
[Journal Article] Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate2021
- Author(s)
  Ota Tomoki、Senoo Akinobu、Shirakawa Masumi、Nonaka Hiroshi、Saito Yutaro、Ito Sho、Ueno Go、Nagatoishi Satoru、Tsumoto Kouhei、Sando Shinsuke
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 2 Pages: 102036-102036
- DOI
  10.1016/j.isci.2021.102036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19J14451
[Journal Article] Author Correction: Structure-based design and discovery of novel anti-tissue factor antibodies with cooperative double-point mutations, using interaction analysis2021
- Author(s)
  Chiba Shuntaro、Tanabe Aki、Nakakido Makoto、Okuno Yasushi、Tsumoto Kouhei、Ohta Masateru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18153-18153
- DOI
  10.1038/s41598-021-97892-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme2021
- Author(s)
  Akiba Hiroki、Tamura Hiroko、Caaveiro Jose M M、Tsumoto Kouhei
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 5 Pages: 623-629
- DOI
  10.1093/jb/mvab082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-17H06109
[Journal Article] Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3.2021
- Author(s)
  Ten T, Nagatoishi S, Maeda R, Hoshino M, Nakayama Y, Seiki M, Sakamoto T, Tsumoto K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 297 Issue: 5 Pages: 101304-101304
- DOI
  10.1016/j.jbc.2021.101304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Peptoid-based reprogrammable template for cell-permeable inhibitors of protein?protein interactions2021
- Author(s)
  Fukuda Y, Yokomine M, Kuroda D, Tsumoto K, Morimoto J, Sando S.
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 40 Pages: 13292-13300
- DOI
  10.1039/d1sc01560e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19H04202
[Journal Article] Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion2021
- Author(s)
  Senoo Akinobu、Ito Sho、Nagatoishi Satoru、Saito Yutaro、Ueno Go、Kuroda Daisuke、Yoshida Kouhei、Tashima Takumi、Kudo Shota、Sando Shinsuke、Tsumoto Kouhei
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1041-1041
- DOI
  10.1038/s42003-021-02575-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PLANNED-19H05766
[Journal Article] Anion solvation enhanced by positive supercharging mutations preserves thermal stability of an antibody in a wide pH range2021
- Author(s)
  Kasahara Keisuke、Kuroda Daisuke、Tanabe Aki、Kawade Raiji、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 563 Pages: 54-59
- DOI
  10.1016/j.bbrc.2021.05.053
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H04202
[Journal Article] Elaboration of Non-naturally Occurring Helical Tripeptides as p53–MDM2/MDMX Interaction Inhibitors2021
- Author(s)
  Su Aoze、Tabata Yuko、Aoki Kiyono、Sada Akane、Ohki Rieko、Nagatoishi Satoru、Tsumoto Kouhei、Wang Siyuan、Otani Yuko、Ohwada Tomohiko
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 7 Pages: 681-692
- DOI
  10.1248/cpb.c21-00238
- NAID
  130008060029
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07605, KAKENHI-PROJECT-18H02552, KAKENHI-PROJECT-20H02531
[Journal Article] Mechanism of dimerization and structural features of human LI-cadherin2021
- Author(s)
  Yui Anna、Caaveiro Jose M.M.、Kuroda Daisuke、Nakakido Makoto、Nagatoishi Satoru、Goda Shuichiro、Maruno Takahiro、Uchiyama Susumu、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Issue: 3 Pages: 101054-101054
- DOI
  10.1016/j.jbc.2021.101054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival2021
- Author(s)
  Nishinaga Megumi、Sugimoto Hiroshi、Nishitani Yudai、Nagai Seina、Nagatoishi Satoru、Muraki Norifumi、Tosha Takehiko、Tsumoto Kouhei、Aono Shigetoshi、Shiro Yoshitsugu、Sawai Hitomi
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 467-467
- DOI
  10.1038/s42003-021-01987-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05761, KAKENHI-PLANNED-19H05762, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-17H03093, KAKENHI-PROJECT-18K05321, KAKENHI-PUBLICLY-20H05451, KAKENHI-PROJECT-21H02064, KAKENHI-PROJECT-21H02421, KAKENHI-PROJECT-20K06517, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF12021
- Author(s)
  Kori Satomi、Shibahashi Yuki、Ekimoto Toru、Nishiyama Atsuya、Yoshimi Sae、Yamaguchi Kosuke、Nagatoishi Satoru、Ohta Masateru、Tsumoto Kouhei、Nakanishi Makoto、Defossez Pierre-Antoine、Ikeguchi Mitsunori、Arita Kyohei
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 52 Pages: 116500-116500
- DOI
  10.1016/j.bmc.2021.116500
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-18H05426, KAKENHI-PUBLICLY-21H00272, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05741
[Journal Article] A glutamine sensor that directly activates TORC12021
- Author(s)
  Tanigawa Mirai、Yamamoto Katsuyoshi、Nagatoishi Satoru、Nagata Koji、Noshiro Daisuke、Noda Nobuo N.、Tsumoto Kouhei、Maeda Tatsuya
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1093-1093
- DOI
  10.1038/s42003-021-02625-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-18H02151, KAKENHI-PROJECT-20H03251, KAKENHI-PROJECT-20K06555, KAKENHI-PROJECT-19K16344, KAKENHI-PROJECT-20H02531
[Journal Article] Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support2021
- Author(s)
  Ito Toshihiro、Minamitani Takeharu、Hayakawa Masaki、Otsubo Ryota、Akiba Hiroki、Tsumoto Kouhei、Matsumoto Masanori、Yasui Teruhito
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 22341-22341
- DOI
  10.1038/s41598-021-01696-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16641, KAKENHI-PROJECT-20K08479, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K16403
[Journal Article] B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice2021
- Author(s)
  Lee MSL, Inoue T, Ise W, Matsuo-Dapaah J, Wing JB, Temizoz B, Kobiyama K, Hayashi T, Patil A, Sakaguchi S, Simon AK, Bezbradica JS, Nagatoishi S, Tsumoto K, Inoue J, Akira S, Kurosaki T, Ishii KJ, Coban C
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 219 Issue: 2
- DOI
  10.1084/jem.20211336
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02749, KAKENHI-PROJECT-20H03503, KAKENHI-PROJECT-20H02531
[Journal Article] Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-12021
- Author(s)
  Queliconi BB, Kojima W, Kimura M, Imai K, Udagawa C, Motono C, Hirokawa T, Tashiro S, Caaveiro JMM, Tsumoto K, Yamano K, Tanaka K, Matsuda N
- Journal Title
  
  J Cell Sci
  
  Volume: 134 Issue: 22 Pages: 1-1
- DOI
  10.1242/jcs.258653
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-18H02443, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-20H02531
[Journal Article] Thermodynamic Dissection of Potency and Selectivity of Cytosolic Hsp90 Inhibitors2021
- Author(s)
  Yoshimura Chihoko、Nagatoishi Satoru、Kuroda Daisuke、Kodama Yasuo、Uno Takao、Kitade Makoto、Chong-Takata Khoontee、Oshiumi Hiromi、Muraoka Hiromi、Yamashita Satoshi、Kawai Yuichi、Ohkubo Shuichi、Tsumoto Kouhei
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 5 Pages: 2669-2677
- DOI
  10.1021/acs.jmedchem.0c01715
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells2021
- Author(s)
  Eguchi Akihiro、Ueki Ayaka、Hoshiyama Junya、Kuwata Keiko、Chikaoka Yoko、Kawamura Takeshi、Nagatoishi Satoru、Tsumoto Kouhei、Ueki Ryosuke、Sando Shinsuke
- Journal Title
  
  JACS Au
  
  Volume: n/a Issue: 5 Pages: 578-585
- DOI
  10.1021/jacsau.0c00121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15693, KAKENHI-PROJECT-20H02531
[Journal Article] A new twist of rubredoxin function in M. tuberculosis2021
- Author(s)
  Sushko Tatsiana、Kavaleuski Anton、Grabovec Irina、Kavaleuskaya Anna、Vakhrameev Daniil、Bukhdruker Sergey、Marin Egor、Kuzikov Alexey、Masamrekh Rami、Shumyantseva Victoria、Tsumoto Kouhei、Borshchevskiy Valentin、Gilep Andrei、Strushkevich Natallia
- Journal Title
  
  Bioorganic Chemistry
  
  Volume: 109 Pages: 104721-104721
- DOI
  10.1016/j.bioorg.2021.104721
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis2021
- Author(s)
  Sekiya Motohiro、Kainoh Kenta、Sugasawa Takehito、Yoshino Ryunosuke、Hirokawa Takatsugu、Tokiwa Hiroaki、Nakano Shogo、Nagatoishi Satoru、Tsumoto Kouhei、Takeuchi Yoshinori、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41467-021-26638-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-20H02531
[Journal Article] Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies2021
- Author(s)
  Ikeuchi E, Kuroda D, Nakakido M, Murakami A, Tsumoto K.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20624-20624
- DOI
  10.1038/s41598-021-98977-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-17H06109, KAKENHI-PROJECT-19H04202
[Journal Article] Development of biparatopic bispecific antibody possessing tetravalent scFv-Fc capable of binding to ROBO1 expressed in hepatocellular carcinoma cells2021
- Author(s)
  Watanabe Yuji、Tanabe Aki、Hamakubo Takao、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 2 Pages: 307-315
- DOI
  10.1093/jb/mvab049
- NAID
  40022722450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Characterization of a putative maltodextrin-binding protein of Streptococcus pyogenes, SPs0871 and the development of a VHH inhibitor2021
- Author(s)
  Yamawaki T, Nakakido M, Ujiie K, Aikawa C, Nakagawa I, Tsumoto K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 6 Pages: 1-7
- DOI
  10.1016/j.bbrc.2021.05.056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07537, KAKENHI-PROJECT-18KK0193, KAKENHI-PUBLICLY-20H05504, KAKENHI-PROJECT-19H03471, KAKENHI-PROJECT-21K19376, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] A Novel Cell-Based Intracellular Protein?Protein Interaction Detection Platform (SOLIS) for Multimodality Screening2021
- Author(s)
  Kashima Daiki、Kageoka Miho、Kimura Yosuke、Horikawa Makiko、Miura Masashi、Nakakido Makoto、Tsumoto Kouhei、Nagamune Teruyuki、Kawahara Masahiro
- Journal Title
  
  ACS Synthetic Biology
  
  Volume: 10 Issue: 5 Pages: 990-999
- DOI
  10.1021/acssynbio.0c00483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-23K21062
[Journal Article] Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR2021
- Author(s)
  Kosuge Hirofumi、Nakakido Makoto、Nagatoishi Satoru、Fukuda Tetsuya、Bando Yasuhiko、Ohnuma Shin-ichi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100278-100278
- DOI
  10.1016/j.jbc.2021.100278
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Microsecond molecular dynamics suggest that a non-synonymous mutation, frequently observed in patients with mild symptoms in Tokyo, alters dynamics of the SARS-CoV-2 main protease2021
- Author(s)
  Kuroda D, Tsumoto K.
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 18 Issue: 0 Pages: 215-222
- DOI
  10.2142/biophysico.bppb-v18.022
- NAID
  130008088919
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H04202
[Journal Article] Electrostatic-triggered exothermic antibody adsorption to the cellulose nanoparticles2021
- Author(s)
  Murakami Keisuke、Nagatoishi Satoru、Kasahara Keisuke、Nagai Hirokazu、Sasajima Yoshiyuki、Sasaki Ryo、Tsumoto Kouhei
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 632 Pages: 114337-114337
- DOI
  10.1016/j.ab.2021.114337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Structural Basis for the Binding Mechanism of Human Serum Albumin Complexed with Cyclic Peptide Dalbavancin2020
- Author(s)
  Ito Sho、Senoo Akinobu、Nagatoishi Satoru、Ohue Masahito、Yamamoto Masaki、Tsumoto Kouhei、Wakui Naoki
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 63 Issue: 22 Pages: 14045-14053
- DOI
  10.1021/acs.jmedchem.0c01578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19926, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19J14451
[Journal Article] Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening2020
- Author(s)
  Miyazaki Takuya、Uchida Satoshi、Nagatoishi Satoru、Koji Kyoko、Hong Taehun、Fukushima Shigeto、Tsumoto Kouhei、Ishihara Kazuhiko、Kataoka Kazunori、Cabral Horacio
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 9 Issue: 16 Pages: 2000538-2000538
- DOI
  10.1002/adhm.202000538
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-20H04524
[Journal Article] Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand2020
- Author(s)
  Kosuge Hirofumi、Nagatoishi Satoru、Kiyoshi Masato、Ishii‐Watabe Akiko、Tanaka Toru、Terao Yosuke、Oe Seigo、Ide Teruhiko、Tsumoto Kouhei
- Journal Title
  
  Biotechnology Progress
  
  Volume: 36 Issue: 6
- DOI
  10.1002/btpr.3016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher2020
- Author(s)
  Akiba Hiroki、Takayanagi Kensuke、Kusano-Arai Osamu、Iwanari Hiroko、Hamakubo Takao、Tsumoto Kouhei
- Journal Title
  
  Biotechnology Reports
  
  Volume: 25 Pages: e00418-e00418
- DOI
  10.1016/j.btre.2020.e00418
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-17H06109
[Journal Article] Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain2020
- Author(s)
  Jinbing Xie, Daniel Gonzalez-Carter, Theofilus A. Tockary, Noriko Nakamura, Yonger Xue, Makoto Nakakido, Hiroki Akiba, Anjaneyulu Dirisala, Xueying Liu, Kazuko Toh, Tao Yang, Zengtao Wang, Shigeto Fukushima, Junjie Li, Sabina Quader, Kouhei Tsumoto, Takanori Yokota, Yasutaka Anraku*, and Kazunori Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: - Issue: 6 Pages: 6729-6742
- DOI
  10.1021/acsnano.9b09991
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14100, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-18K18393
[Journal Article] The Kg‐antigen, RhAG with a Lys164Gln mutation, gives rise to haemolytic disease of the newborn2020
- Author(s)
  Tanaka Mitsunobu、Abe Takaaki、Minamitani Takeharu、Akiba Hiroki、Horikawa Toshihiro、Tobita Ryutaro、Isa Kazumi、Ogasawara Kenichi、Takahashi Hideo、Tateyama Hidemi、Tone Satomi、Tsumoto Kouhei、Yasui Teruhito、Kimura Takafumi、Fujimura Yoshihiro、Hirayama Fumiya、Tani Yoshihiko、Takihara Yoshihiro
- Journal Title
  
  British Journal of Haematology
  
  Volume: 191 Issue: 5 Pages: 920-926
- DOI
  10.1111/bjh.16955
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design2020
- Author(s)
  Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 5 Pages: 1631-1651
- DOI
  10.1016/j.xphs.2020.01.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-19H03522
[Journal Article] 64Cu-labeled minibody D2101 visualizes CDH17-positive gastric cancer xenografts with short waiting time2020
- Author(s)
  Fujiwara Kentaro、Akiba Hiroki、Tsuji Atsushi B.、Sudo Hitomi、Sugyo Aya、Nagatsu Kotaro、Zhang Ming-Rong、Iwanari Hiroko、Kusano-Arai Osamu、Kudo Shota、Kikuchi Chika、Tsumoto Kouhei、Momose Toshimitsu、Hamakubo Takao、Higashi Tatsuya
- Journal Title
  
  Nuclear Medicine Communications
  
  Volume: Publish Ahead of Print Issue: 7 Pages: 688-695
- DOI
  10.1097/mnm.0000000000001203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06159, KAKENHI-PROJECT-18H02774, KAKENHI-PROJECT-20H02531
[Journal Article] Unique Electronic Structures of the Highly Ruffled Hemes in Heme-Degrading Enzymes ofStaphylococcus aureus, IsdG and IsdI, by Resonance Raman and Electron Paramagnetic Resonance Spectroscopies2020
- Author(s)
  Takahashi Satoshi、Nambu Shusuke、Matsui Toshitaka、Fujii Hiroshi、Ishikawa Haruto、Mizutani Yasuhisa、Tsumoto Kouhei、Ikeda-Saito Masao
- Journal Title
  
  Biochemistry
  
  Volume: 59 Issue: 40 Pages: 3918-3928
- DOI
  10.1021/acs.biochem.0c00731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05701, KAKENHI-PROJECT-20K21166, KAKENHI-PUBLICLY-19H04581, KAKENHI-PUBLICLY-20H05435, KAKENHI-PROJECT-18H02382, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H02693
[Journal Article] Structure-based design and discovery of novel anti-tissue factor antibodies with cooperative double-point mutations, using interaction analysis2020
- Author(s)
  Chiba Shuntaro、Tanabe Aki、Nakakido Makoto、Okuno Yasushi、Tsumoto Kouhei、Ohta Masateru
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17590-17590
- DOI
  10.1038/s41598-020-74545-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20K16377
[Journal Article] Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody2019
- Author(s)
  Akiba Hiroki、Tamura Hiroko、Kiyoshi Masato、Yanaka Saeko、Sugase Kenji、Caaveiro Jose M. M.、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 15481-15481
- DOI
  10.1038/s41598-019-50722-y
- NAID
  120006822517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18K14892, KAKENHI-PROJECT-17H06109
[Journal Article] An epitope‐directed antibody affinity maturation system utilizing mammalian cell survival as readout2019
- Author(s)
  Eguchi Akihiro、Nakakido Makoto、Nagatoishi Satoru、Kuroda Daisuke、Tsumoto Kouhei、Nagamune Teruyuki、Kawahara Masahiro
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 116 Issue: 7 Pages: 1742-1751
- DOI
  10.1002/bit.26965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H01792, KAKENHI-PROJECT-17K19007, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-17H06109
[Journal Article] How the protonation state of a phosphorylated amino acid governs molecular recognition: insights from classical molecular dynamics simulations2019
- Author(s)
  Kawade Raiji、Kuroda Daisuke、Tsumoto Kouhei
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 5 Pages: 903-912
- DOI
  10.1002/1873-3468.13674
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-19J14494
[Journal Article] Effects of a remote mutation from the contact paratope on the structure of CDR-H3 in the anti-HIV neutralizing antibody PG162019
- Author(s)
  Kondo Hiroko X.、Kiribayashi Ryo、Kuroda Daisuke、Kohda Jiro、Kugimiya Akimitsu、Nakano Yasuhisa、Tsumoto Kouhei、Takano Yu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 19840-19840
- DOI
  10.1038/s41598-019-56154-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06589, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-17H06109
[Journal Article] Phospholipid Membrane Fluidity Alters Ligand Binding Activity of a G Protein-Coupled Receptor by Shifting the Conformational Equilibrium.2019
- Author(s)
  Yoshida K, Nagatoishi S, Kuroda D, Suzuki N, Murata T, Tsumoto K.
- Journal Title
  
  Biochemistry
  
  Volume: 58(6) Issue: 6 Pages: 504-508
- DOI
  10.1021/acs.biochem.8b01194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-16H04710
[Journal Article] Computer-guided library generation applied to the optimization of single-domain antibodies2019
- Author(s)
  Akiba Hiroki、Tamura Hiroko、Caaveiro Jose M M、Tsumoto Kouhei
- Journal Title
  
  Protein Engineering, Design and Selection
  
  Volume: 32 Issue: 9 Pages: 423-431
- DOI
  10.1093/protein/gzaa006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-17H06109
[Journal Article] Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction.2019
- Author(s)
  Nonaka H, Nakanishi Y, Kuno S, Ota T, Mochidome K, Saito Y, Sugihara F, Takakusagi Y, Aoki I, Nagatoishi S, Tsumoto K, Sando S.
- Journal Title
  
  Nat Commun.
  
  Volume: 10(1) Issue: 1 Pages: 876-876
- DOI
  10.1038/s41467-019-08833-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction.2019
- Author(s)
  Chigira T, Nagatoishi S, Takeda H, Yoshimaru T, Katagiri T, Tsumoto K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 518 Issue: 1 Pages: 183-189
- DOI
  10.1016/j.bbrc.2019.08.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06419, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K10551
[Journal Article] Structural features of methionine aminopeptidase2-active core peptide essential for binding with S100A42019
- Author(s)
  Katagiri Naohiro、Nagatoishi Satoru、Tsumoto Kouhei、Endo Hideya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 516 Issue: 4 Pages: 1123-1129
- DOI
  10.1016/j.bbrc.2019.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082
[Journal Article] Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations.2019
- Author(s)
  Yoshida K, Kuroda D, Kiyoshi M, Nakakido M, Nagatoishi S, Soga S, Shirai H, Tsumoto K.
- Journal Title
  
  Sci Rep.
  
  Volume: 9(1) Issue: 1 Pages: 4482-4482
- DOI
  10.1038/s41598-019-40461-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17H06109
[Journal Article] Generation and characterization of antagonistic anti-human interleukin (IL)-18 monoclonal antibodies with high affinity: Two types of monoclonal antibodies against full-length IL-18 and the neoepitope of inflammatory caspase-cleaved active IL-18.2019
- Author(s)
  Nariai Y, Kamino H, Obayashi E, Kato H, Sakashita G, Sugiura T, Migita K, Koga T, Kawakami A, Sakamoto K, Kadomatsu K, Nakakido M, Tsumoto K, Urano T.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 663 Pages: 71-82
- DOI
  10.1016/j.abb.2019.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-19H00340, KAKENHI-PROJECT-17H06109
[Journal Article] Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface2019
- Author(s)
  Yamashita Takefumi、Mizohata Eiichi、Nagatoishi Satoru、Watanabe Takahiro、Nakakido Makoto、Iwanari Hiroko、Mochizuki Yasuhiro、Nakayama Taisuke、Kado Yuji、Yokota Yuki、Matsumura Hiroyoshi、Kawamura Takeshi、Kodama Tatsuhiko、Hamakubo Takao、Inoue Tsuyoshi、Fujitani Hideaki、Tsumoto Kouhei
- Journal Title
  
  Structure
  
  Volume: 27 Issue: 3 Pages: 519-527
- DOI
  10.1016/j.str.2018.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06094, KAKENHI-PUBLICLY-17H05732, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17H06109
[Journal Article] Long-Term Stability and Reversible Thermal Unfolding of Antibody Structure at Low pH: Case Study2018
- Author(s)
  Fukada H, Tsumoto K, Arakawa T, Ejima D.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 107 Issue: 11 Pages: 2965-2967
- DOI
  10.1016/j.xphs.2018.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Inhibition of homophilic dimerization and disruption of cell adhesion by P-cadherin-specific small molecules from SPR-based assays2018
- Author(s)
  Senoo A, Nagatoishi S, Moberg A, Babol LN, Mitani T, Tashima T, Kudo S, Tsumoto K.
- Journal Title
  
  Chemical Communications
  
  Volume: 54 Issue: 42 Pages: 5350-5353
- DOI
  10.1039/c8cc01964a
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-16H04710
[Journal Article] Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery.2018
- Author(s)
  Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 496 Issue: 2 Pages: 614-620
- DOI
  10.1016/j.bbrc.2018.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06693
[Journal Article] Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column2018
- Author(s)
  Kiyoshi M, Caaveiro JMM, Tada M, Tamura H, Tanaka T, Terao Y, Morante K, Harazono A, Hashii N, Shibata H, Kuroda D, Nagatoishi S, Oe S, Ide T, Tsumoto K, Ishii-Watabe A
- Journal Title
  
  Scientific Reports
  
  Volume: 8:3955 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-018-22199-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962
[Journal Article] A combination of 19 F NMR and surface plasmon resonance for site-specific hit selection and validation of fragment molecules that bind to the ATP-binding site of a kinase2018
- Author(s)
  Nagatoishi S, Yamaguchi S, Katoh E, Kajita K, Yokotagawa T, Kanai S, Furuya T, Tsumoto K.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 8 Pages: 1929-1938
- DOI
  10.1016/j.bmc.2018.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-16H04710
[Journal Article] A secondary RET mutation in the activation loop conferring resistance to vandetanib.2018
- Author(s)
  Nakaoku T, Kohno T, Araki M, Niho S, Chauhan R, Knowles PP, Tsuchihara K, Matsumoto S, Shimada Y, Mimaki S, Ishii G, Ichikawa H, Nagatoishi S, Tsumoto K, Okuno Y, Yoh K, McDonald NQ, Goto K
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 625-625
- DOI
  10.1038/s41467-018-02994-7
- NAID
  120006406830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15036, KAKENHI-PROJECT-16H02420
[Journal Article] 12. Improvement of antibody affinity by introduction of basic amino acid residues into the framework region.2018
- Author(s)
  Fukunaga A, Maeta S, Reema B, Nakakido M, Tsumoto K.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 15 Pages: 81-85
- DOI
  10.1016/j.bbrep.2018.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H06109
[Journal Article] Tyrosine sulfation restricts the conformational ensemble of a flexible peptide, strengthening the binding affinity for an antibody2018
- Author(s)
  K. Miyanabe, T. Yamashita, Y. Abe, H. Akiba, Y. Takamatsu, M. Nakakido, T. Hamakubo, T. Ueda, JMM. Caaveiro, and K. Tsumoto
- Journal Title
  
  Biochemistry
  
  Volume: 57 Issue: 28 Pages: 4177-4185
- DOI
  10.1021/acs.biochem.8b00592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0103, KAKENHI-PROJECT-15H05752, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H06109
[Journal Article] PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.2018
- Author(s)
  Moriya C, Taniguchi H, Nagatoishi S, Igarashi H, Tsumoto K, Imai K
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 2 Pages: 373-383
- DOI
  10.1111/cas.13458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710
[Journal Article] Enzymatically Cleavable Traceless Biotin Tag for Protein PEGylation and Purification2018
- Author(s)
  Adam Marcin Wawro, Yusuke Aoki, Takahiro Muraoka, Kouhei Tsumoto, and Kazushi Kinbara
- Journal Title
  
  Chem. Common.
  
  Volume: 印刷中 Issue: 15 Pages: 1913-1916
- DOI
  10.1039/c7cc05814d
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05147, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H04885
[Journal Article] Repertoire analysis of antibody CDR-H3 loops suggests affinity maturation does not typically result in rigidification2018
- Author(s)
  Jeliazkov JR, Sljoka A, Kuroda D, Tsuchimura N, Katoh N, Tsumoto K, Gray JJ
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9:413 Pages: 1-17
- DOI
  10.3389/fimmu.2018.00413
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420
[Journal Article] Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry2018
- Author(s)
  Obi N, Fukuda T, Nakayama N, Ervin J, Bando Y, Nishimura T, Nagatoishi S, Tsumoto K, Kawamura T.
- Journal Title
  
  Rapid Communications in Mass Spectrometry
  
  Volume: 32 Issue: 8 Pages: 665-671
- DOI
  10.1002/rcm.8083
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Biophysical Analysis of the Protein-Small Molecule Interactions to Develop Small Molecule Drug Discovery2018
- Author(s)
  Nagatoishi S, Caaveiro JMM, Tsumoto K.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 8 Pages: 1033-1041
- DOI
  10.1248/yakushi.17-00211-2
- NAID
  130007429352
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Antibody Affinity Maturation by Computational Design.2018
- Author(s)
  Kuroda D, Tsumoto K.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1827 Pages: 15-34
- DOI
  10.1007/978-1-4939-8648-4_2
- ISBN
  9781493986477, 9781493986484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition.2018
- Author(s)
  Takahashi T, Nagatoishi S, Kuroda D, Tsumoto K.
- Journal Title
  
  PLoS One
  
  Volume: 13(10) Issue: 10 Pages: e0204856-e0204856
- DOI
  10.1371/journal.pone.0204856
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Structures of the prefusion form of measles virus fusion protein in complex with inhibitors2018
- Author(s)
  Hashiguchi T, Fukuda Y, Matsuoka R, Kuroda D, Kubota M, Shirogane Y, Watanabe S, Tsumoto K, Kohda D, Plemper RK, Yanagi Y
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 115(10) Issue: 10 Pages: 2496-2501
- DOI
  10.1073/pnas.1718957115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420
[Journal Article] Synergistic Cytotoxic Effect on Gastric Cancer Cells of an Immunotoxin Cocktail in Which Antibodies Recognize Different Epitopes on CDH172018
- Author(s)
  Kusano-Arai O, Iwanari H, Kudo S, Akiba H, Matsusaka K, Kaneda A, Fukayama M, Tsumoto K, Hamakubo T.
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 37 Issue: 1 Pages: 1-11
- DOI
  10.1089/mab.2017.0043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-16H05412
[Journal Article] Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis2018
- Author(s)
  Ohara Yukiko、Ozeki Yuriko、Tateishi Yoshitaka、Mashima Tsukasa、Arisaka Fumio、Tsunaka Yasuo、Fujiwara Yoshie、Nishiyama Akihito、Yoshida Yutaka、Kitadokoro Kengo、Kobayashi Haruka、Kaneko Yukihiro、Nakagawa Ichiro、Maekura Ryoji、Yamamoto Saburo、Katahira Masato、Matsumoto Sohkichi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 10 Pages: 0204160-0204160
- DOI
  10.1371/journal.pone.0204160
- NAID
  120006534592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-18K08172, KAKENHI-PROJECT-16H05187, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16K14048, KAKENHI-PROJECT-17K19552
[Journal Article] Characterization of glycoengineered anti-HER2 monoclonal antibodies produced by using a silkworm?baculovirus expression system2018
- Author(s)
  Egashira Y, Nagatoishi S, Kiyoshi M, Ishii-Watabe A, Tsumoto K.
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 163 Issue: 6 Pages: 481-488
- DOI
  10.1093/jb/mvy021
- NAID
  40021579952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082
[Journal Article] Structural behavior of keratin-associated protein 8.1 in human hair as revealed by a monoclonal antibody.2018
- Author(s)
  Akiba H, Ikeuchi E, Ganbat J, Fujikawa H, Arai-Kusano O, Iwanari H, Nakakido M, Hamakubo T, Shimomura Y, Tsumoto K.
- Journal Title
  
  J Struct Biol.
  
  Volume: 204(2) Issue: 2 Pages: 207-214
- DOI
  10.1016/j.jsb.2018.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H06109
[Journal Article] Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody.2018
- Author(s)
  Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  J. Biochem.
  
  Volume: in press Issue: 1 Pages: 65-76
- DOI
  10.1093/jb/mvy032
- NAID
  40021625331
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Discovery and Optimization of Inhibitors of the Parkinson’s Disease Associated Protein DJ-12018
- Author(s)
  Tashiro Shinya、Caaveiro Jose M. M.、Nakakido Makoto、Tanabe Aki、Nagatoishi Satoru、Tamura Yasushi、Matsuda Noriyuki、Liu Dali、Hoang Quyen Q.、Tsumoto Kouhei
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 13 Issue: 9 Pages: 2783-2793
- DOI
  10.1021/acschembio.8b00701
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-17J07322, KAKENHI-PROJECT-17K19338, KAKENHI-PROJECT-15H05705, KAKENHI-PROJECT-16H04710
[Journal Article] Enhanced intracellular delivery of siRNA by controlling ATP-responsivity of phenylboronic acid-functionalized polyion complex micelles.2018
- Author(s)
  M. Naito, N. Yoshinaga, T. Ishii, A. Matsumoto, Y. Miyahara, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Biosci.
  
  Volume: 1 Issue: 1
- DOI
  10.1002/mabi.201700357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25000006
[Journal Article] Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin2018
- Author(s)
  Takumi Tashima , Satoru Nagatoishi, Jose M.M. Caaveiro, Makoto Nakakido, Hiroshi Sagara, Osamu Kusano-Arai, Hiroko Iwanari, Hitomi Mimuro, Takao Hamakubo, Shin-ichi Ohnuma and Kouhei Tsumoto
- Journal Title
  
  Communications Biology
  
  Volume: 1:33 Issue: 1 Pages: 1-10
- DOI
  10.1038/s42003-018-0038-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17J10207, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K19551, KAKENHI-PLANNED-18H05425
[Journal Article] Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity2018
- Author(s)
  Kawade R, Akiba H, Entzminger K, Maruyama T, Okumura CJ, Tsumoto K.
- Journal Title
  
  Protein Engineering, Design and Selection
  
  Volume: 31 Issue: 7-8 Pages: 243-247
- DOI
  10.1093/protein/gzy008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H06109
[Journal Article] Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen.2017
- Author(s)
  Yumura K, Akiba H, Nagatoishi S, Kusano-Arai O, Iwanari H, Hamakubo T, Tsumoto K.
- Journal Title
  
  J. Biochem.
  
  Volume: 162 Issue: 3 Pages: 203-210
- DOI
  10.1093/jb/mvx023
- NAID
  40021326109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-25000006
[Journal Article] Biophysical characterization of the interaction between heme and proteins responsible for heme transfer in Streptococcus pyogenes.2017
- Author(s)
  Hoshino M, Nakakido M, Nagatoishi S, Aikawa C, Nakagawa I, Tsumoto K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Issue: 2 Pages: 1109-1114
- DOI
  10.1016/j.bbrc.2017.09.055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08775, KAKENHI-PROJECT-17K19552, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16H06693
[Journal Article] Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer.2017
- Author(s)
  F. Perche, S. Uchida, H. Akiba, C.-Y. Lin, M. Ikegami, A. Disrala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka
- Journal Title
  
  Curr. Alzheimer Res.
  
  Volume: 14 Issue: 3 Pages: 295-302
- DOI
  10.2174/1567205013666161108110031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H02420
[Journal Article] Elucidation of potential sites for antibody engineering by fluctuation editing2017
- Author(s)
  Yanaka Saeko、Moriwaki Yoshitaka、Tsumoto Kouhei、Sugase Kenji
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 9597-9597
- DOI
  10.1038/s41598-017-10246-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05893, KAKENHI-PROJECT-16H02420
[Journal Article] Insight in the Evolution of Therapeutic Monoclonal Antibodies<br/>—Fundamental Technologies for Creation and Evaluation of Next Generation mAbs—2017
- Author(s)
  Ishii-Watabe A, Tsumoto K.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 137 Issue: 7 Pages: 815-816
- DOI
  10.1248/yakushi.16-00252-F
- NAID
  130007287840
- ISSN
  0031-6903, 1347-5231
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Analysis of Pore Formation and Protein Translocation Using Large Biological Nanopores.2017
- Author(s)
  Watanabe H, Gubbiotti A, Chinappi M, Takai N, Tanaka K, Tsumoto K and Kawano R
- Journal Title
  
  Anal. Chem.
  
  Volume: 89 Issue: 21 Pages: 11269-11277
- DOI
  10.1021/acs.analchem.7b01550
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06043
[Journal Article] Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin2017
- Author(s)
  S. Kudo, J. M. M. Caaveiro, S. Nagatoishi, T. Miyafusa, T. Matsuura, Y. Sudou, and K. Tsumoto
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 39518-39518
- DOI
  10.1038/srep39518
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011
[Journal Article] Polymeric SpyCatcher Scaffold Enables Bioconjugation in a Ratio-Controllable Manner.2017
- Author(s)
  Jia L, Minamihata K, Ichinose H, Tsumoto K and Kamiya N
- Journal Title
  
  Biotechnol. J.
  
  Volume: 12 Pages: 1700195-1700195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Production and characterization of genetically modified human IL-11 variants.2017
- Author(s)
  Sano E, Takei T, Ueda T, Tsumoto K.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1861 Issue: 2 Pages: 205-217
- DOI
  10.1016/j.bbagen.2016.11.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Therapeutic Vesicular Nanoreactors with Tumor-Specific Activation and Self-Destruction for Synergistic Tumor Ablation2017
- Author(s)
  Li Junjie、Dirisala Anjaneyulu、Ge Zhishen、Wang Yuheng、Yin Wei、Ke Wendong、Toh Kazuko、Xie Jinbing、Matsumoto Yu、Anraku Yasutaka、Osada Kensuke、Kataoka Kazunori
- Journal Title
  
  Angew Chem Int Ed Engl
  
  Volume: 56 Issue: 45 Pages: 14025-14030
- DOI
  10.1002/anie.201706964
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-15K12536, KAKENHI-PROJECT-25000006
[Journal Article] Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers2017
- Author(s)
  A. Pica, I. R. Krauss, V. Parente, H. Tateishi-Karimata, S. Nagatoishi, K. Tsumoto, N. Sugimoto, and F. Sica
- Journal Title
  
  Nucleic Acids Res., 45, 461-469 (2017)
  
  Volume: 45 Issue: 1 Pages: 461-469
- DOI
  10.1093/nar/gkw1113
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02283, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-26810094, KAKENHI-PROJECT-16H02420
[Journal Article] Structural basis for binding and transfer of heme in bacterial heme-acquisition systems2017
- Author(s)
  Naoe Youichi、Nakamura Nozomi、Rahman Md. Mahfuzur、Tosha Takehiko、Nagatoishi Satoru、Tsumoto Kouhei、Shiro Yoshitsugu、Sugimoto Hiroshi
- Journal Title
  
  Proteins: Structure, Function, and Bioinformatics
  
  Volume: 85 Issue: 12 Pages: 2217-2230
- DOI
  10.1002/prot.25386
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05896, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03092
[Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017
- Author(s)
  Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2001-2009
- DOI
  10.1038/s41467-017-00952-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Functional contacts between MPER and the anti-HIV-1 broadly neutralizing antibody 4E10 extend into the core of the membrane2017
- Author(s)
  Rujas, E., Insausti, S., Garcia-Porras, M., Sanchez-Eugenia, R., Tsumoto, K., Nieva, J.L., and Caaveiro, J.M.M.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 429 Issue: 8 Pages: 1213-1226
- DOI
  10.1016/j.jmb.2017.03.008
- NAID
  120006328970
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Peripheral membrane interactions boost the engagement by an anti HIV-1 broadly neutralizing antibody2017
- Author(s)
  Rujas, E., Caaveiro, J.M.M., Insausti, S., Garcia-Porras, M., Tsumoto, K., and Nieva, J.L.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Issue: 13 Pages: 5571-5583
- DOI
  10.1074/jbc.m117.775429
- NAID
  120006328971
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011
[Journal Article] Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity.2017
- Author(s)
  Lee Y, Nishizawa T, Takemoto M, Kumazaki K, Yamashita K, Hirata K, Minoda A, Nagatoishi S, Tsumoto K, Ishitani R and Nureki O.
- Journal Title
  
  Nature Plants.
  
  Volume: 3 Issue: 10 Pages: 825-832
- DOI
  10.1038/s41477-017-0022-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-16J07405, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
[Journal Article] Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1.2017
- Author(s)
  Yui A, Akiba H, Kudo S, Nakakido M, Nagatoishi S and Tsumoto K
- Journal Title
  
  J. Biochem.
  
  Volume: 162 Pages: 255-258
- DOI
  10.1093/jb/mvx050
- NAID
  40021380511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06693, KAKENHI-PROJECT-25000006
[Journal Article] Haemolytic actinoporins interact with carbohydrates using their lipid-binding module.2017
- Author(s)
  Tanaka K, Caaveiro JMM, Morante K and Tsumoto K.
- Journal Title
  
  Philos. Trans. R. Soc. B.
  
  Volume: 372 Issue: 1726 Pages: 20160216-20160216
- DOI
  10.1098/rstb.2016.0216
- NAID
  120006328969
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962
[Journal Article] Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.2016
- Author(s)
  Suzuki T, Nagatoishi S, Tsumoto K, Abe T. (全41人，5番目と25番目)
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles2016
- Author(s)
  Yi, Y., Kim, H. J., Mi, P., Zheng, M., Takemoto, H., Toh, K., Kim, B. S., Hayashi, K., Naito, M., Matsumoto, Y., Miyata, K., Kataoka, K.
- Journal Title
  
  J Control Release
  
  Volume: 244 Pages: 247-256
- DOI
  10.1016/j.jconrel.2016.08.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Identification of a membrane-bound prepore species clarifies the lytic mechanism of actinoporins2016
- Author(s)
  Morante, K., Bellomio, A., Gil-Carton, D., Redondo-Morata, L., Sot, J., Scheuring, S., Valle, M., Gonzalez-Manas, J.M., Tsumoto, K., and Caaveiro, J.M.M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 37 Pages: 19210-19219
- DOI
  10.1074/jbc.m116.734053
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.2016
- Author(s)
  Kado Y1, Mizohata E2, Nagatoishi S3, Iijima M4, Shinoda K4, Miyafusa T3, Nakayama T2, Yoshizumi T2, Sugiyama A4, Kawamura T4, Lee YH4, Matsumura H2, Doi H4, Fujitani H4, Kodama T4, Shibasaki Y4, Tsumoto K5, Inoue T6.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Issue: 5 Pages: 2319-2330
- DOI
  10.1074/jbc.m115.656009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670377, KAKENHI-PROJECT-15K17882, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25440022, KAKENHI-PROJECT-25282230, KAKENHI-PUBLICLY-26102526
[Journal Article] Assessment of the Protein-Protein Interactions in a Highly Concentrated Antibody Solution by Using Raman Spectroscopy.2016
- Author(s)
  Ota C, Noguchi S, Nagatoishi S, Tsumoto K
- Journal Title
  
  Pharm. Res.
  
  Volume: 33(4) Issue: 4 Pages: 956-969
- DOI
  10.1007/s11095-015-1842-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Differential effect of membrane composition on the pore forming ability of four different sea anemone actinoporins2016
- Author(s)
  Garcia-Linares, S., Rivera-de-Torre, E., Morante, K., Tsumoto, K., Caaveiro, J.M.M., Gavilanes, J.G., Slotte, J.P., and Martinez-del-Pozo, A.
- Journal Title
  
  Biochemistry
  
  Volume: 55 Issue: 48 Pages: 6630-6641
- DOI
  10.1021/acs.biochem.6b01007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals TGFBR2 as a Novel Regulator of Glioblastoma Stem Cell Properties2016
- Author(s)
  Narushima Y, Kozuka-Hata H, Koyama-Nasu R, Tsumoto K, Inoue J, Akiyama T & Oyama M.
- Journal Title
  
  Molecular and Cellular Proteomics
  
  Volume: 15 Issue: 3 Pages: 1017-1031
- DOI
  10.1074/mcp.m115.049999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-26505001, KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-26290036
[Journal Article] In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis.2016
- Author(s)
  Sigala PA, Morante K, Tsumoto K, Caaveiro JM, Goldberg DE.
- Journal Title
  
  Biochemistry
  
  Volume: 55 Issue: 34 Pages: 4836-4849
- DOI
  10.1021/acs.biochem.6b00562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Journal Article] Quantitative phosphoproteomics-based molecular network description for high-resolution kinase-substrate interactome analysis.2016
- Author(s)
  Narushima, Y., Kozuka-Hata, H., Tsumoto, K., Inoue, J. and Oyama, M.
- Journal Title
  
  Bioinformatics
  
  Volume: 印刷中 Issue: 14 Pages: 2083-2088
- DOI
  10.1093/bioinformatics/btw164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-26290036, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06578, KAKENHI-PROJECT-26505001, KAKENHI-PROJECT-16H02420
[Journal Article] Adhesive dimerization of human P-cadherin catalyzed by a chaperone-like mechanism2016
- Author(s)
  Kudo, S., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  Structure
  
  Volume: 24 Issue: 9 Pages: 1523-1536
- DOI
  10.1016/j.str.2016.07.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420
[Journal Article] Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface2016
- Author(s)
  Rujas, E., Caaveiro, J.M.M., Partida-Hanon, A., Gulzar, N., Morante, K., Apellaniz, B., Garcia-Porras, M., Bruix, M., Tsumoto, K., Scott, J.K., Jimenez, M.A., and Nieva, J.L.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 38177-38177
- DOI
  10.1038/srep38177
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420
[Journal Article] Reply to "The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?"2016
- Author(s)
  Rujas E, Gulzar N, Morante K, Tsumoto K, Scott JK, Nieva JL, Caaveiro JM
- Journal Title
  
  J. Virol.
  
  Volume: 90(6) Issue: 6 Pages: 3276-3277
- DOI
  10.1128/jvi.02970-15
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting2016
- Author(s)
  Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 113 Pages: 253-265
- DOI
  10.1016/j.biomaterials.2016.10.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178
[Journal Article] Structural basis for amino-acid export by DMT superfamily transporter YddG2016
- Author(s)
  H. Tsuchiya, S. Doki, M. Takemoto, T. Ikuta, T. Higuchi, K. Fukui, Y. Usuda, E. Tabuchi, S. Nagatoishi, K. Tsumoto, T. Nishizawa, K. Ito, N. Dohmae, R. Ishitani and O. Nureki
- Journal Title
  
  Nature
  
  Volume: 534 Issue: 7607 Pages: 417-420
- DOI
  10.1038/nature17991
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26410190, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H02420
[Journal Article] pH responsiveness of fibrous assemblies of repeat-sequence amphipathic α-helix polypeptides.2015
- Author(s)
  Takei T, Tsumoto K, Okonogi A, Kimura A, Kojima S, Yazaki K, Takei T, Ueda T, Miura K.
- Journal Title
  
  Protein Sci.
  
  Volume: 24(5) Issue: 5 Pages: 883-894
- DOI
  10.1002/pro.2665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Bidirectional transformation of a protein between its Native Water-Soluble and Transmembrane Conformations.2015
- Author(s)
  Tanaka, K., Caaveiro, J.M.M., and Tsumoto, K.
- Journal Title
  
  Biochemistry
  
  Volume: 54 Issue: 46 Pages: 6863-6866
- DOI
  10.1021/acs.biochem.5b01112
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-24000011
[Journal Article] Thermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions.2015
- Author(s)
  Akiba H, Tsumoto K.
- Journal Title
  
  J. Biol. chem
  
  Volume: 158(1) Issue: 1 Pages: 1-13
- DOI
  10.1093/jb/mvv049
- NAID
  40020522493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011
[Journal Article] Differential binding of prohibitin-2 to estrogen receptor α and to drug-resistant ERα mutants.2015
- Author(s)
  Chigira T, Nagatoishi S, Tsumoto K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 463 Issue: 4 Pages: 726-731
- DOI
  10.1016/j.bbrc.2015.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011
[Journal Article] Differential Effects of IFN-β on the Survival and Growth of Human Vascular Smooth Muscle and Endothelial Cells.2015
- Author(s)
  Sano E, Tashiro S, Tsumoto K, Ueda T.
- Journal Title
  
  Biores Open Access.
  
  Volume: 4(1) Issue: 1 Pages: 1-15
- DOI
  10.1089/biores.2014.0052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172
[Journal Article] Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.2015
- Author(s)
  Bai Y, Tashiro S, Nagatoishi S, Suzuki T, Yan D, Liu R, Tsumoto K, Bartlam M, Yamamoto T.
- Journal Title
  
  Protein Cell.
  
  Volume: 6 Issue: 12 Pages: 924-928
- DOI
  10.1007/s13238-015-0225-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172
[Journal Article] Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.2015
- Author(s)
  Nakano K, Chigira T, Miyafusa T, Nagatoishi S, Caaveiro JM, Tsumoto K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 15337-15337
- DOI
  10.1038/srep15337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115
[Journal Article] Osteomodulin regulates diameter and alters shape of collagen fibrils.2015
- Author(s)
  Tashima T, Nagatoishi S, Sagara H, Ohnuma S, Tsumoto K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 463 Issue: 3 Pages: 292-296
- DOI
  10.1016/j.bbrc.2015.05.053
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115
[Journal Article] A Pore-Forming Toxin Requires a Specific Residue for its Activity in Membranes with Particular Physicochemical Properties2015
- Author(s)
  Koldo Morante, Jose M.M. Caaveiro, Koji Tanaka, Juan Manuel Gonzalez-Manas and Kouhei Tsumoto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: M114 Issue: 17 Pages: 615211-615211
- DOI
  10.1074/jbc.m114.615211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-25249115
[Journal Article] Rapid Heme Transfer Reactions between NEAr Transporter Domains of Staphylococcus aureus: A Theoretical Study Using QM/MM and MD Simulations.2015
- Author(s)
  Moriwaki Y, Terada T, Tsumoto K, Shimizu K.
- Journal Title
  
  PLoS One
  
  Volume: 10(12) Issue: 12 Pages: e0145125-e0145125
- DOI
  10.1371/journal.pone.0145125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Structural Analysis of Fc/FcγR Complexes: A Blueprint for Antibody Design.2015
- Author(s)
  Caaveiro, J.M.M., Kiyoshi, M. and Tsumoto, K.
- Journal Title
  
  Immunological Reviews
  
  Volume: 268 Issue: 1 Pages: 201-221
- DOI
  10.1111/imr.12365
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25000006
[Journal Article] The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region2015
- Author(s)
  Apellaniz B, Rujas E, Serrano S, Morante K, Tsumoto K, Caaveiro JM, Jimenez MA, Nieva JL.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 (21) Issue: 21 Pages: 12999-13015
- DOI
  10.1074/jbc.m115.644351
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.2015
- Author(s)
  Nakayama T, Mizohata E, Yamashita T, Nagatoishi S, Nakakido M, Iwanari H, Mochizuki Y, Kado Y, Yokota Y, Satoh R, Tsumoto K, Fujitani H, Kodama T, Hamakubo T, Inoue T.
- Journal Title
  
  Protein Sci
  
  Volume: 24 Issue: 3 Pages: 328-340
- DOI
  10.1002/pro.2619
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] Structural basis for self-assembly of a cytolytic pore lined by protein and lipid2015
- Author(s)
  Koji Tanaka, Jose M.M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas and Kouhei Tsumoto
- Journal Title
  
  Nature Communications
  
  Volume: 6 Issue: 1 Pages: 6337-6337
- DOI
  10.1038/ncomms7337
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25249115
[Journal Article] Protein stabilization by an amphiphilic short monodisperse oligo(ethylene glycol)2015
- Author(s)
  Nabanita Sadhukhan, Takahiro Muraoka, Mihoko Ui, Satoru Nagatoishi, Kouhei Tsumoto, Kazushi Kinbara
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 40 Pages: 8457-8460
- DOI
  10.1039/c4cc10301g
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26410170, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25410166
[Journal Article] Structural basis for binding of human IgG1 to its high-affinity human receptor FcgRI2015
- Author(s)
  Kiyoshi M, Caaveiro JM, Kawai T, Tashiro S, Ide T, Asaoka Y, Hatayama K, Tsumoto K.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 6866-6866
- DOI
  10.1038/ncomms7866
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172, KAKENHI-PROJECT-25000006
[Journal Article] Functional characterization of Val60, a key residue in the membrane-oligomerization of fragaceatoxin C, an Actinoporin from Actinia fragacea2015
- Author(s)
  Morante K, Caaveiro JM, Viguera AR, Tsumoto K, Gonzalez-Manas JM
- Journal Title
  
  FEBS Lett.
  
  Volume: 589(15) Issue: 15 Pages: 1840-1846
- DOI
  10.1016/j.febslet.2015.06.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Journal Article] Structural and thermodynamics basis of epitope binding to neutralizing and non-neutralizing forms of the anti-HIV-1 4E10 antibody2015
- Author(s)
  Rujas, E., Gulzar, N., Morante, K., Tsumoto, K., Scott, J.K., Nieva, J.L. and Caaveiro, J.M.M.
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 23 Pages: 11975-11991
- DOI
  10.1128/jvi.01793-15
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115
[Journal Article] Thermodynamic characterization of the interaction between human Y-box binding protein YB-1 and nucleic acids2015
- Author(s)
  Tanabe Y, Nagatoishi S, Tsumoto K.
- Journal Title
  
  Mol. Biosyst.
  
  Volume: 11 Issue: 9 Pages: 2441-2448
- DOI
  10.1039/c5mb00184f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011
[Journal Article] Reversible Ion Transportation Switch by a Ligand-Gated Synthetic Supramolecular Ion Channel2014
- Author(s)
  Takahiro Muraoka, Takahiro Endo, Kazuhito V. Tabata, Hiroyuki Noji, Satoru Nagatoishi, Kouhei Tsumoto, Rui Li and Kazushi Kinbara
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136 Issue: 44 Pages: 15584-15595
- DOI
  10.1021/ja5070312
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-25249115
[Journal Article] Role of Positions e and g in the Fibrous Assembly Formation of an Amphipathic alpha-Helix-Forming Polypeptide2014
- Author(s)
  Takei, T.
- Journal Title
  
  Biopolymers
  
  Volume: in press Issue: 3 Pages: 260-72
- DOI
  10.1002/bip.22479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247013, KAKENHI-PROJECT-23570190, KAKENHI-PROJECT-25249115
[Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles2014
- Author(s)
  H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 9 Pages: 8979-8991
- DOI
  10.1021/nn502125h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Affinity Improvement of a Therapeutic Antibody by Structure-Based Computational Design : Generation of Electrostatic Interactions in the Transition State Stabilizes the Antibody-Antigen Complex2014
- Author(s)
  Masato Kiyoshi, Jose M.M. Caaveiro, Eri Miura, Satoru Nagatoishi, Makoto Nakakido, Shinji Soga, Hiroki Shirai, Shigeki Kawabata, Kouhei Tsumoto
- Journal Title
  
  Plos One
  
  Volume: 9 Issue: 1 Pages: e87099-e87099
- DOI
  10.1371/journal.pone.0087099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25000006
[Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors2014
- Author(s)
  Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 10 Pages: 3416-3426
- DOI
  10.1016/j.biomaterials.2013.12.086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
[Journal Article] Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014
- Author(s)
  Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 27 Pages: 7887-7895
- DOI
  10.1016/j.biomaterials.2014.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Alternative downstream processes for production of antibodies and antibody fragments2014
- Author(s)
  Tsutomu Arakawa, Kouhei Tsumoto, Daisuke Ejima
- Journal Title
  
  Biochimica et Biophysica Acta - Proteins and Proteomics
  
  Volume: 1844 Issue: 11 Pages: 2032-2040
- DOI
  10.1016/j.bbapap.2014.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011
[Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2014
- Author(s)
  Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Drug Delivery and Translational Research
  
  Volume: 4 Issue: 1 Pages: 50-60
- DOI
  10.1007/s13346-013-0175-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Identification and Characterization of the X-Dimer of Human P-Cadherin : Implications for Homophilic Cell Adhesion2014
- Author(s)
  Shota Kudo, Jose M. M. Caaveiro, Shuichiro Goda, Satoru Nagatoishi, Keisuke Ishii, Tadashi Matsuura, Yukio Sudou, Tatsuhiko Kodama, Takao Hamakubo, and Kouhei Tsumoto
- Journal Title
  
  Biochemistry
  
  Volume: 53(11) Issue: 11 Pages: 1742-1752
- DOI
  10.1021/bi401341g
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J04678, KAKENHI-PROJECT-24000011, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25450133
[Journal Article] The staphylococcal elastin-binding protein regulates zinc-dependent growth/biofilm formation.2014
- Author(s)
  M. Nakakido, C. Aikawa, I. Nakagawa, K. Tsumoto.
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 156 Issue: 3 Pages: 155-162
- DOI
  10.1093/jb/mvu027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J06919, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25125708, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25293370, KAKENHI-PROJECT-26860285
[Journal Article] Grafting Synthetic Transmembrane Units to the Engineered Low-Toxicity alpha-Hemolysin to Restore Its Hemolytic Activity2014
- Author(s)
  Mihoko Ui, Kousuke Harima, Toshiaki Takei, Kouhei Tsumoto, Kazuhito V. Tabata, Hiroyuki Noji, Sumire Endo, Kimio Akiyama, Takahiro Muraoka, and Kazushi Kinbara
- Journal Title
  
  Molecular Biosystems
  
  Volume: 10 Issue: 12 Pages: 3199-3206
- DOI
  10.1039/c4mb00405a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25410166
[Journal Article] Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer2014
- Author(s)
  T. Nomoto, S. Fukushima, M. Kumagai, K. Machitani, Arnida, Y. Matsumoto, M. Oba, K. Miyata, K. Osada, N. Nishiyama, K. Kataoka
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3545-3545
- DOI
  10.1038/ncomms4545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25670010
[Journal Article] Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class Ⅰ complex2014
- Author(s)
  Saeko Yanaka, Takamasa Ueno, Yi Shi, Jianxun Gi, George F. Gao, Kouhei Tsumoto, and Kenji Sugase
- Journal Title
  
  J Biol Chem.
  
  Volume: 268 Issue: 35 Pages: 24680-90
- DOI
  10.1074/jbc.m114.566174
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25133706, KAKENHI-PROJECT-25249115
[Journal Article] Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-12014
- Author(s)
  Shinya Tashiro, Jose M. M. Caaveiro, Chun-Xiang Wu, Quyen Q. Hoang, Kouhei Tsumoto
- Journal Title
  
  Biochemistry
  
  Volume: 53(14) Issue: 14 Pages: 2218-2220
- DOI
  10.1021/bi500294h
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J08172, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25249115
[Journal Article] Protective effect of the long pentraxin PTX3 against histone-mediated endothelial cell cytotoxicity in sepsis.2014
- Author(s)
  Daigo K, Nakakido M, Ohashi R, Fukuda R, Matsubara K, Minami T, Yamaguchi N, Inoue K, Jiang S, Naito M, Tsumoto K, Hamakubo T.
- Journal Title
  
  Sci Signal
  
  Volume: 7 Issue: 343
- DOI
  10.1126/scisignal.2005522
- NAID
  120005537769
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24591070, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26640069
[Journal Article] Bidirectional binding property of high glycine-tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair2013
- Author(s)
  Ryo Matsunaga, Ryota Abe, Daisuke Ishii, Shun-ichi Watanabe, Masato Kiyoshi, Bernd Nöcker, Masaru Tsuchiya, Kouhei Tsumoto
- Journal Title
  
  Journal of Structural Biology
  
  Volume: 183 Issue: 3 Pages: 484-494
- DOI
  10.1016/j.jsb.2013.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J05539, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115
[Journal Article] Heme binding mechanism of structurally similar iron-regulated surface determinant near transporter domains of Staphylococcus aureus exhibiting different affinities for heme.2013
- Author(s)
  Yoshitaka Moriwaki
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 49 Pages: 8866-8877
- DOI
  10.1021/bi4008325
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J06526, KAKENHI-PROJECT-23300109, KAKENHI-PROJECT-24000011, KAKENHI-PUBLICLY-24102516, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25708026
[Journal Article] Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus2013
- Author(s)
  Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka, Kouhei Tsumoto
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 23 Pages: 3824-3830
- DOI
  10.1016/j.febslet.2013.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011
[Journal Article] Hyperthin nanochains composed of self-polymerizing protein shackles2013
- Author(s)
  Ryo Matsunaga, Saeko Yanaka, Satoru Nagatoishi, Kouhei Tsumoto
- Journal Title
  
  Nature Communications
  
  Volume: 4 Issue: 1 Pages: 2211-2211
- DOI
  10.1038/ncomms3211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J05539, KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25249115
[Journal Article] Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus2013
- Author(s)
  Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka, Martin E. Tanner, Kouhei Tsumoto
- Journal Title
  
  Bioscience Reports
  
  Volume: 33 Issue: 3 Pages: 463-474
- DOI
  10.1042/bsr20130017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115
[Journal Article] Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers2013
- Author(s)
  Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
- Journal Title
  
  Macromolecules
  
  Volume: 46 Issue: 16 Pages: 6585-6592
- DOI
  10.1021/ma401093z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] Selective binding of antimicrobial porphyrins to the hame-receptor IsdH-NEAT3 of Staphylococcus aureus.2013
- Author(s)
  Nhuan Vu
- Journal Title
  
  Protein Science
  
  Volume: 22 Issue: 7 Pages: 942-953
- DOI
  10.1002/pro.2276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J06526, KAKENHI-PROJECT-23300109, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115
[Journal Article] Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress2013
- Author(s)
  Takahiko Ito, Kouhei Tsumoto
- Journal Title
  
  Protein Science
  
  Volume: 22 Issue: 11 Pages: 1542-1551
- DOI
  10.1002/pro.2340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011
[Journal Article] Directed Evolution and Structural Analysis of NADPH-Dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) Reductase from Ralstonia eutropha Reveals Two Mutations Responsible for Enhanced Kinetics2013
- Author(s)
  Ken'ichiro Matsumoto, Yoshikazu Tanaka, Tsuyoshi Watanabe, Ren Motohashi, Koji Ikeda, Kota Tobitani, Min Yao, Isao Tanaka, Seiichi Taguchi
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 79 Issue: 19 Pages: 6134-6139
- DOI
  10.1128/aem.01768-13
- NAID
  120005411137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011
[Journal Article] Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide2013
- Author(s)
  Matsui T, Nambu S, Ono Y, Goulding CW, Tsumoto K, Ikeda-Saito M.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 18 Pages: 3025-3027
- DOI
  10.1021/bi400382p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011, KAKENHI-ORGANIZER-24120001, KAKENHI-PLANNED-24120006, KAKENHI-PROJECT-24350081, KAKENHI-PUBLICLY-25109504
[Journal Article] Effects of Chain Length of an Amphipathic Polypeptide Carrying the Repeated Amino Acid Sequence (LETLAKA)(n) on α-Helix and Fibrous Assembly Formation.2013
- Author(s)
  Takei T., et al
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 16 Pages: 2810-2820
- DOI
  10.1021/bi400001c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227006, KAKENHI-PROJECT-23247013, KAKENHI-PROJECT-25249115
[Journal Article] Improving the affinity of an antibody for its antigen via long-range electrostatic interactions2013
- Author(s)
  Atsushi Fukunaga, Kouhei Tsumoto
- Journal Title
  
  Protein Engineering Design & Selection
  
  Volume: 26 Issue: 12 Pages: 773-780
- DOI
  10.1093/protein/gzt053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011
[Journal Article] Crystal Structure of Enzyme CapF of Staphylococcus aureus Reveals a Unique A rchitecture Composed of Two Functional Domains2012
- Author(s)
  Miyafusa T, Caaveiro JM, Tanaka Y, Tsumoto K
- Journal Title
  
  Biochemical journal
  
  Volume: (印刷中) Issue: 3 Pages: 671-680
- DOI
  10.1042/bj20112049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07066, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-24655145
[Journal Article] Establishment of a microcarrier culture system with serial sub-cultivation for functionally active human endothelial cells2012
- Author(s)
  Tashiro S, Tsumoto K, Sano E
- Journal Title
  
  J.Biotechnol.
  
  Volume: (印刷中) Issue: 3-4 Pages: 202-213
- DOI
  10.1016/j.jbiotec.2012.02.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Mapping the ultra-weak protein-protein interactions between heme transporters of Staphylococcus aureus2012
- Author(s)
  Ryota Abe, Jose M.M.Caaveiro, Hiroko Kozuka-Hata, Masaaki Oyama, Kouhei Tsumoto
- Journal Title
  
  Journal of biological chemistry
  
  Volume: (印刷中) Issue: 20 Pages: 16477-16487
- DOI
  10.1074/jbc.m112.346700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06068, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-23510254
[Journal Article] Interleukin-11 Links Oxidative Stress and Compensatory Proliferation2012
- Author(s)
  Nishina T, Komazawa-Sakon S, Yanaka S, Zheng X, Palo J, Kojima Y, Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M, Kouhei T, Okamura K, Nakano H
- Journal Title
  
  Science Signal
  
  Volume: 5 Issue: 207
- DOI
  10.1126/scisignal.2002056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06193, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23659404, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-24700705, KAKENHI-PROJECT-24790328, KAKENHI-PUBLICLY-23117717
[Journal Article] Catalytic activity of MsbA reconstituted in nanodisc particles is modulated by remote interactions with the bilayer2011
- Author(s)
  Kawai T, Caaveiro JM, Abe R, Katagiri T, Tsumoto K
- Journal Title
  
  FEBS Lett
  
  Volume: 585 Issue: 22 Pages: 3533-3537
- DOI
  10.1016/j.febslet.2011.10.015
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Refolding single-chain antibody(scFv) using lauroyl-L-glutamate as a solubilization detergent and arginine as a refolding additive2011
- Author(s)
  Motonori Kudou ; Daisuke Ejima ; Haruna Sato ; Ryosuke Yumioka ; Tsutomu Arakawa ; and Kouhei Tsumoto
- Journal Title
  
  Protein Exp. Purif
  
  Volume: 77 Issue: 1 Pages: 68-74
- DOI
  10.1016/j.pep.2010.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] A novel protein refolding system using lauroyl-l-glutamate as a solubilizing detergent and arginine as a folding assisting agent2011
- Author(s)
  Kudou M, Yumioka R, Ejima D, Arakawa T, Tsumoto K
- Journal Title
  
  Protein Expr Purif
  
  Volume: 75 Issue: 1 Pages: 46-54
- DOI
  10.1016/j.pep.2010.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Gene expression profiling predicts response to temozolomide in malignant gliomas.2011
- Author(s)
  Yoshino A, Ogino A, Yachi K, Ohta T, Fukushima T, Watanabe T, Katayama Y, Okamoto Y, Naruse N, Sano E, Tsumoto K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 36(6) Pages: 1367-1377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Chemical and Pharmacological Chaperones : Application for Recombinant Protein Production and Protein Folding Diseases2011
- Author(s)
  Rahul S. Rajan, Kouhei Tsumoto, Masao Tokunaga, Hiroko Tokunaga, Yoshiko Kita and Tsutomu Arakawa
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 18 Issue: 1 Pages: 1-15
- DOI
  10.2174/092986711793979698
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Hydration is Required in DNA G-Quadruplex-Protein Binding2011
- Author(s)
  Nagatoishi S, Isono N, Tsumoto K, Sugimoto N
- Journal Title
  
  Chembiochem.
  
  Volume: 12 Issue: 12 Pages: 1822-1826
- DOI
  10.1002/cbic.201100264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-22655057
[Journal Article] A novel protein refolding system using lauroy1-1-glutamate as a solubilizing detergent and arginine as a folding assisting agent.2011
- Author(s)
  Kudou M, Yumioka R, Ejima D, Arakawa T, Tsumoto K.
- Journal Title
  
  Protein Exp.Purif.
  
  Volume: 印刷中掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Chemical and Pharmacological Chaperones : Application for Recombinant Protein Production and Protein Folding Diseases.2011
- Author(s)
  Rajan R S, Tsumoto K, Tokunaga M, Tokunaga H, Kita Y, Arakawa T
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 18(1) Pages: 11-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Stepwise Characterization of the Thermodynamics of Trichocyte Intermediate Filament Protein Supramolecular Assembly2011
- Author(s)
  Ishii D, Abe R, Watanabe SI, Tsuchiya M, Nocker B, Tsumoto K
- Journal Title
  
  J. Mol. Biol
  
  Volume: 408 Issue: 5 Pages: 832-838
- DOI
  10.1016/j.jmb.2011.03.034
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas2011
- Author(s)
  Yoshino A, Tashiro S, Ogino A, Yachi K, Ohta T, Fukushima T, Watanabe T, Katayama Y, Okamoto Y, Sano E, Tsumoto K
- Journal Title
  
  Int J Oncol.
  
  Volume: 39 Pages: 529-542
- DOI
  10.3892/ijo.2011.1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Molecular Basis of Recognition of Antibacterial Porphyrins by Heme-Transporter IsdH-NEAT3 of Staphylococcus aureus2011
- Author(s)
  Moriwaki Y, Caaveiro JM, Tanaka Y, Tsutsumi H, Hamachi I, Tsumoto K
- Journal Title
  
  Biochemistry
  
  Volume: 50 Issue: 34 Pages: 7311-7320
- DOI
  10.1021/bi200493h
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Non-core region modulates interleukin-11 signaling activity : Generation of agonist and antagonist variants2011
- Author(s)
  Yanaka S, Sano E, Naruse N, Miura KI, Futatsumori-Sugai M, Caaveiro JM, Tsumoto K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Issue: 10 Pages: 8085-8093
- DOI
  10.1074/jbc.m110.152561
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Monoubiquitination of Tob/BTG family proteins competes with degradation-targeting polyubiquitination.2011
- Author(s)
  Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 409 Issue: 1 Pages: 70-4
- DOI
  10.1016/j.bbrc.2011.04.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21360398, KAKENHI-PUBLICLY-23121506, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-23689027
[Journal Article] Refolding single-chain antibody (scFv) using lauroyl-L-glutamate as a solubilization detergent and arginine as a refolding additive.2011
- Author(s)
  Kudou M, Ejima D, Sato H, Yumioka R, Arakawa T, Tsumoto K
- Journal Title
  
  Protein Exp.Purif.
  
  Volume: 印刷中掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladder-like Polycyclic Ether and the Anti-Ciguatoxin Antibody 10C9Fab2011
- Author(s)
  Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, Kouhei Tsumoto
- Journal Title
  
  Molecular BioSystems
  
  Volume: 7 Issue: 3 Pages: 793-798
- DOI
  10.1039/c0mb00162g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladder-like Polycyclic Ether and the Anti-Ciguatoxin Antibody 10C9Fab2011
- Author(s)
  Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, and Kouhei Tsumoto
- Journal Title
  
  Molecular Bio Systems
  
  Volume: 7 Pages: 793-798
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Molecular basis of recognition of antibacterial porphyrions by heme-transoprter IsdH-NEAT3 of Staphylococcus aureus Biochemistry2011
- Author(s)
  Moriwaki, Y., Caaveiro, J.M.M., Tanaka, Y., Tsutsumi, H., Hamachi, I., Tsumoto, K.
- Journal Title
  
  Biochemistry
  
  Volume: 50 Pages: 7211-7320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Non-core region modulates interleukin-11 signaling activity : Generation of agonist and antagonist variants.2011
- Author(s)
  Yanaka S, Sano E, Naruse N, More KI, Futatsumori-Sugai M, Caaveiro JM, Tsumoto K
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 印刷中掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladde r-like Polycychc Ether and the Anti-Ciguatoxin Antibody 10C9Fab.2011
- Author(s)
  Ui M, Tanaka Y, Tsumuraya T, Fujii I, Inoue M, Hirama M, Tsumoto K
- Journal Title
  
  Mol.BioSyst.
  
  Volume: 印刷中掲載確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex : HyHEL-10-HEL2010
- Author(s)
  Yokota A., Tsumoto K., Shiroishi M., Nakanishi T., Kondo H., Kumagai I
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 10 Pages: 7686-7696
- DOI
  10.1074/jbc.m109.089623
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Temperature and salt concentration alter base-sequence selectivity of a duplex DNA-binding protein2010
- Author(s)
  Nagatoishi S, Tanaka Y, Kudou M and Tsumoto K
- Journal Title
  
  Mol. Biosyst
  
  Volume: 6 Issue: 1 Pages: 98-101
- DOI
  10.1039/b914828k
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] An approach to rational ligand-design based on a thermodynamic analysis2010
- Author(s)
  Ui M, Tsumoto K
- Journal Title
  
  Recent Pat Biotechnol
  
  Volume: 4 Issue: 3 Pages: 183-188
- DOI
  10.2174/187220810793611482
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Step-Wise Refolding of Recombinant Proteins.2010
- Author(s)
  Tsumoto K, Arakawa T, Chen L.
- Journal Title
  
  Curr Pharm Biotechnol.
  
  Volume: 11(3) Pages: 285-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Non-Denaturing Solubilization of Inclusion Bodies.2010
- Author(s)
  津本浩平
- Journal Title
  
  Curr Pharm Biotechnol. (掲載確定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Direct and Selective Immobilization of Proteins by Means of an Inorgan is Material-Binding Peptide : Discussion on Functionalization in the Elongation to Material-Binding Peptide.2010
- Author(s)
  Yokoo N, Thgashi T, Umetsu M, Tsumoto K, Hattori T, Nakanishi T, Ohera S, Takami S, Naka T, Abe H, Kumagai I, Adschiri T.
- Journal Title
  
  J.Phys.Chem.B.
  
  Volume: 114(1) Pages: 480-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Salicylate-induced translocation of prestin having mutation in the GTSRH sequence to the plasma membrane.2010
- Author(s)
  Kumano S, Iida K, Ishihara K, Murakoshi M, Tsumoto K, Ikeda K, Kumagai I, Kobayashi T, Wada H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584(11) Pages: 2327-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Contribution of the flexible loop region to the function of Staphylococcal enterotoxin B (SEB)2010
- Author(s)
  Yanaka S, Kudou M, Tanaka Y, Sasaki T, Takemoto S, Sakata A, Hattori Y, Koshi T, Futaki S, Tsumoto K, Nakashima T
- Journal Title
  
  Protein Eng.Des.Select.
  
  Volume: 23(5) Pages: 415-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Contribution of the flexible loop region to the function of Staphylococcal enterotoxin B(SEB)2010
- Author(s)
  Saeko Yanaka, Motonori Kudou, Yoshikazu Tanaka, Takumi Sasaki, Sumiyo Takemoto, Atsuko Sakata Yukio Hattori, Tomoyuki Koshi, Shiro Futaki, Kouhei Tsumoto, and Toshihiro Nakashima
- Journal Title
  
  Protein Eng. Des. Select
  
  Volume: 23 Issue: 5 Pages: 415-421
- DOI
  10.1093/protein/gzq006
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Signal peptide design for improving recombinant protein secretion in the baculovirus expression vector system2010
- Author(s)
  Futatsumori-Sugai M and Tsumoto K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 391 Issue: 1 Pages: 931-935
- DOI
  10.1016/j.bbrc.2009.11.167
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] The structural mechanism of the inhibition of archaeal Re1E toxin by its cognate Re1B antitoxin.2010
- Author(s)
  Shinohara M, Guo JX, Mori M, Nakashima T, Takagi H, Nishimoto E, Yamashita S, Tsumoto K, Kakuta Y, Kimura M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 400(3) Pages: 346-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Step-Wise Refolding of Recombinant Proteins.2010
- Author(s)
  津本浩平
- Journal Title
  
  Curr Pharm Biotechnol. (掲載確定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Reactive oxygen species induced by Streptococcus pyogenes invasion trigger apoptotic cell death in infected epithelial cells.2010
- Author(s)
  Aikawa C, Nozawa T, Maruyama F, Tsumoto K, Hamada S, Nakagawa I.
- Journal Title
  
  Cell Microbiol.
  
  Volume: 12(6) Pages: 814-830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Expression of antibody variable region-human alkaline pbosphatase fusion proteins in mammalian cells.2010
- Author(s)
  Sasajima Y, Iwasaki R, Tsumoto K, Kumagai I, Ihara M, Ueda H.
- Journal Title
  
  J Immunol Methods.
  
  Volume: 361(1-2) Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Salicylate restores transport function and anion exchanger activity of missense pendrin mutations.2010
- Author(s)
  Ishihara K, Okuyama S, Kumano S, Iida K, Hamana H, Murakoshi M, Kobayashi T, Usami S, Ikeda K, Haga Y, Tsumoto K Nakamura H, Hirasawa N, Wada H.
- Journal Title
  
  Hear Res.
  
  Volume: 270(1-2) Pages: 110-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Signal peptide design for improving recombinant protein secretion in the baculovirus expression vector system2010
- Author(s)
  Futatsumori-Sugai M, Tsumoto K
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 391(1) Pages: 931-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents2010
- Author(s)
  Ryota Abe, Jose M. M. Caaveiro, Motonori Kudou and Kouhei Tsumoto
- Journal Title
  
  Mol. Bio Syst
  
  Volume: 6 Issue: 4 Pages: 677-679
- DOI
  10.1039/b925791h
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents.2010
- Author(s)
  Ryota Abe, Jose M.M.Caaveiro, Motonori Kudou, Kouhei Tsumoto
- Journal Title
  
  Mol.BioSyst.
  
  Volume: 6 Pages: 677-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex : HyHEL-10-HEL2010
- Author(s)
  Yokota A., Tsumoto K., Shiroishi M., Nakanishi T., Kondo H., Kumagai I
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 7686-7696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Antigen-antibody Binding2010
- Author(s)
  Kumagai I., 津本浩平
- Journal Title
  
  Encyclopedia of Life Sciences (掲載確定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Non-Denaturing Solubilization of Inclusion Bodies.2010
- Author(s)
  Tsumoto K, Abe R, Ejima D, Arakawa T.Non-Denaturing Solubilization of Inclusion Bodies.
- Journal Title
  
  Curr Pharm Biotechnol.
  
  Volume: 11(3) Pages: 309-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Reactive oxygen species induced by Streptococcus pyogenes invasion trigger apoptotic cell death in infected epithelial cells2010
- Author(s)
  Aikawa C, Nozawa T, Maruyama F, Tsumoto K, Hamada S, Nakagawa I
- Journal Title
  
  Cell Microbiol
  
  Volume: 12 Issue: 6 Pages: 814-830
- DOI
  10.1111/j.1462-5822.2010.01435.x
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] 抗原抗体相互作用の熱力学的解析:特異性と親和性2009
- Author(s)
  津本浩平
- Journal Title
  
  熱測定 36
  
  Pages: 205-215
- NAID
  10025613091
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] To be excluded or to bind, that is the question : Arginine effects on proteins2009
- Author(s)
  Nakakido M, Kudou M, Arakawa T, and Tsumoto K
- Journal Title
  
  Curr. Pharm. Biotechnol
  
  Volume: 10 Pages: 415-420
- URL
  http://www.benthamdirect.org/pages/content.php?CPB/2009/00000010/00000004/0010G.SGM
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Contributions of interfacial residues of human Interleukin15 to the specificity and affinity for its private alpha-receptor2009
- Author(s)
  Sakamoto S, Jose M. M. Caaveiro, Sano E, Tanaka Y, Kudou M and Tsumoto K
- Journal Title
  
  J. Mol. Biol
  
  Volume: 389 Issue: 5 Pages: 880-894
- DOI
  10.1016/j.jmb.2009.04.050
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Immobilized metal affinity chromatography in the presence of arginine2009
- Author(s)
  Abe R, Kudou M, Tanaka Y, Arakawa T and Tsumoto K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 381 Issue: 3 Pages: 306-310
- DOI
  10.1016/j.bbrc.2009.01.054
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Utilization of an arginine-elution method for FLAG-tag chromatography2009
- Author(s)
  Futatsumori-Sugai M, Abe R, Watanabe M, Kudou M, Yamamoto T, Ejima D, Arakawa T, and Tsumoto K
- Journal Title
  
  Protein Expr Purif
  
  Volume: 67 Issue: 2 Pages: 148-155
- DOI
  10.1016/j.pep.2009.03.012
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] 相互作用の熱力学情報に基づく低分子リガンド設計2009
- Author(s)
  津本浩平
- Journal Title
  
  薬学雑誌 (掲載確定, 印刷中)
- NAID
  130000136119
- Data Source
  KAKENHI-PROJECT-21360398
[Journal Article] Grafting of material-binding function into antibodies Functionalization by peptide grafting2008
- Author(s)
  Hattori T, Umetsu M, Nakanishi T, Tsumoto K, Ohara S, Abe H, Naito M, Asano R, Adschiri T, Kumagai I.
- Journal Title
  
  Biochem Biophys Res Commun. 365
  
  Pages: 751-757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] アミノ酸を利用したクロマトグラフィー2008
- Author(s)
  工藤、津本
- Journal Title
  
  月刊バイオテクノロジー (掲載確定)
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Grafting of material-binding function into antibodies Functionalization by peptide grafting2008
- Author(s)
  Hattori T., Umetsu M., Nakanishi T., Tsumoto K., Ohara S., Abe H., Naito M.,Asano R., Adschiri T., Kumagai I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 365
  
  Pages: 751-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
- Author(s)
  Kouhei Tsumoto
- Journal Title
  
  The Journal of Biological Chemistry 283
  
  Pages: 12259-12266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Expression, Purification, Crystallization, and Primary Diffraction Analysis of CapF, a Capsular Polysaccharide Synthesis Enzyme from Staphylococcus aureus2008
- Author(s)
  Takamitsu Miyafusa, Yoshikazu Tanaka, Makoto Kuroda, Toshiko Ohta, Kouhei Tsumoto
- Journal Title
  
  Acta Crystallogr. F (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Thermodynamic consequences of mutations in Vernier zone residues of a humanized anti-human epidermal growth factor receptor (EGFR) murine antibody, 5282008
- Author(s)
  Makabe K., Nakanishi T., Tsumoto K., Tanaka Y., Kondo H., Umetsu M., Sone Y., Asano R., Kumagai I.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 1156-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings:The case of ciguatoxin CTX3C-ABC and its specific antibody IC492008
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J Biol Chem (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] アミノ酸を利用したクロマトグラフィー2008
- Author(s)
  工藤、津本
- Journal Title
  
  月刊バイオテクノロジー (印刷中)
- Data Source
  KAKENHI-PROJECT-19021011
[Journal Article] Critical contribution of VH-VL interaction to reshaping of an antibody : the case of humanization of anti-lysozyme antibody, HyHEL-102008
- Author(s)
  Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I.
- Journal Title
  
  Protein Sci. 17(2)
  
  Pages: 261-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings : The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
- Author(s)
  Tsumoto K^*, Yokota A, Tanaka Y, Ui M, Tsumuraya T, Fujii I, Kumagai I, Nagumo Y, Oguri H, Inoue M, Hirama M.
- Journal Title
  
  J Biol Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effect of an amyloidogenic sequence attached to yellow fluorescent protein2008
- Author(s)
  Hamada D, Tsumoto K, Sawara M, Tanaka N, Nakahira K, Shiraki K, Yanagihara I.
- Journal Title
  
  Proteins Struct. Funct. Bioinfor (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Critical Contribution of VH-VL Interaction to Reshaping of an Antibody : The case of humanization of anti-lysozyme antibody, HyHEL-102008
- Author(s)
  Nakanishi T., Tsumoto K., Yokota A., Kondo H., Kumagai I.
- Journal Title
  
  Protein Sci. 17
  
  Pages: 261-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] A helical string of alternately connected three-helix bundles for the cell wall-associated adhesion protein Ebb from Staphylococcus aureus2008
- Author(s)
  Tanaka Y, Sakamoto S, Kuroda M, Goda S, Gao YG, Tsumoto K, Hiragi Y, Yao M, Watanabe N, Ohta T, Tanaka I.
- Journal Title
  
  Structure 16(3)
  
  Pages: 488-496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
- Author(s)
  Tsumoto K., Yokota A., Tanaka Y., Ui M., Tsumuraya T., Fujii I., Kumagai I., Nagumo Y., Oguri H., Inoue M., Hirama M.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 12259-12266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings2008
- Author(s)
  Tsumoto K, et.al.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 12259-12266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021011
[Journal Article] Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 5282008
- Author(s)
  Makabe K, Nakanishi T, Tsumoto K, Tanaka Y, Kondo H, Umetsu M, Sane Y, Asano R, Kumagai I.
- Journal Title
  
  J Biol Chem. 283(2)
  
  Pages: 1156-1166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings: The case of cituatoxin CTX3C-ABC and its specific antibody 1C49.2008
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J. Biol Chem. (印刷中)(掲載決定)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Thermodynamic analysis reveals that GTP binding affects the interaction between the alpha- and gamma-subunits of translatio initiation factor 22008
- Author(s)
  Nakakido M, Tanaka Y, Sokabe M, Tsumoto K.
- Journal Title
  
  Biochem Biophys Res Commun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] How Protein Recognizes Ladder-like Polycycfic Ethers : Interactions between Ciguatoxin (CTX3C) Fragments and Its specific antibody 10C92008
- Author(s)
  Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, Kouhei Tsumoto
- Journal Title
  
  J. Biol. Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings: The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.2008
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J Biol Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021011
[Journal Article] Molecular properties. of two proteins homologous to PduO-type ATP : cob(I)alamin adenosyltransferase from Sulfolobus tokodaii2007
- Author(s)
  Tanaka Y, Sasaki T, Kumagai 1, Yasutake Y, Yao M, Tanaka I, Tsumoto K
- Journal Title
  
  Proteins Struct. Funct. Bioinfor. 68
  
  Pages: 446-457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Suppression of protein interactions by arginine : A proposed mechanism of arginine effects2007
- Author(s)
  Arakawa T, Ejima D, Tsumoto K, Obeyama N, Tanaka Y, Kita Y, Timasheff S. N.
- Journal Title
  
  Biophys Chem. 127
  
  Pages: 1-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Circular dichroism spectra demonstrate formation of the thrombin-binding DNA aptamer G-quadruplex under stabilizing-cation-deficient conditions2007
- Author(s)
  Nagatoishi S, Tanaka Y, Tsumoto K.
- Journal Title
  
  Biochem. Biophys. Res. Comm. 352
  
  Pages: 812-817
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J. Chromatogr. A 1154
  
  Pages: 81-86
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Structural consequences of mutaof a protein antigen-antibody complex. The case of HyHEL-10-HEL2007
- Author(s)
  Shiroishi M., Tsumoto K., Tanaka Y., Yokota A., Nakanishi T., Kondo H., Kumagai I.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 6783-6791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] A Human antibody fragment with high affinity for biodegradable polymer film2007
- Author(s)
  Watanabe H., Tsumoto K., Taguchi S., Yamashita K., Doi Y., Nishimiya Y., Kondo H., Umetsu M., Kumagai I.
- Journal Title
  
  Bioconjug. Chem. 18
  
  Pages: 645-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography2007
- Author(s)
  Tsumoto K, Ejima D, Senczuk A. M, Kita Y, Arakawa T
- Journal Title
  
  J Pharmaceut. Sci. 96
  
  Pages: 1677-1690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] A Human Antibody Fragment with High Affinity for Biodegradable Polymer Film2007
- Author(s)
  Watanabe H, Tsumoto K, Taguchi S, Yamasbita K, Doi Y, Nishimiya Y, Kondo H, Umetsu M, Kumagai I.
- Journal Title
  
  Bioconjugate Chem. 18
  
  Pages: 645-651
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effects of salts on protein-surface interactions:applications for column chromatography2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J Pharmaceut.Sci 96
  
  Pages: 1677-1690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J.Chromatogr. A 1154
  
  Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021011
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
- Author(s)
  Tsumoto K et al.
- Journal Title
  
  J. Chromatogr. A (印刷中)
- Data Source
  KAKENHI-PROJECT-18038007
[Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography.2007
- Author(s)
  Tsumoto K et al.
- Journal Title
  
  J.Pharmaceut.Sci. (印刷中)
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Improved performance of column chromatography by arginine : Dye-affinity chromatography2007
- Author(s)
  Arakawa T, Ejima D, Tsumoto K, Isbibashi M, Tokunaga M
- Journal Title
  
  Protein Expr. Puri. 52
  
  Pages: 410-414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography.2007
- Author(s)
  Tsumoto K et al.
- Journal Title
  
  J. Pharmaceut. Sci. (印刷中)
- Data Source
  KAKENHI-PROJECT-18038007
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
- Author(s)
  Tsumoto K et al.
- Journal Title
  
  J.Chromatogr.A (印刷中)
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies2007
- Author(s)
  Ejima D, Tsumoto K, Fukada H, Yumioka R, Nagase K, Arakawa T and Philo J. S.
- Journal Title
  
  Proteins Struct. Funct. Bioinfor. 66
  
  Pages: 954-962
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Induced binding of proteins by ammonium sulfate in affinity and ion-exchange column chromatography2007
- Author(s)
  Arakawa T, Tsumoto K, Ejinua D, Kita Y, Yonezawa Y, Tokunaga M
- Journal Title
  
  J. Biochem Biophys. Methods 70
  
  Pages: 493-498
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effects of salts on protein-surface interactions: applications for column chromatography.2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J. Pharmaceut. Sci. 96
  
  Pages: 1677-1690
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex : The case of HyHEL-10-HEL2007
- Author(s)
  Shiroishi M, Tsumoto K, Tanaka Y, Yokota A, Nakanishi T, Kondo H, Kumagai I.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 6783-6791
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Crystal structure analysis reveals a novel forkhead-associated (FHA) domain of ESAT-6 secretion system C (EssC) protein in Staphylococcus aureus2007
- Author(s)
  Tanaka Y, Kuroda M, Yasutake Y, Yao M, Tsumoto K, Watanabe M, Ohta T, Tanaka I
- Journal Title
  
  Proteins Struct. Funct. Bioinfor. 69
  
  Pages: 659-664
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effects of salts on protein-surface interactions: applications for column chromatography.2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J Pharmaceut. Sci. 96
  
  Pages: 1677-1690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021011
[Journal Article] Structural and Mutational analyses of Drp35 from Staphylococcus aureus : a possible mechanism for its lactonase activity2007
- Author(s)
  Tanaka Y, Morikawa K, Ohki Y, Yao. M, Tsumoto K, Watanabe N, Ohta T, Tanaka I
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 5770-5780
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] The effects of arginine on protein binding and elution in hydrophobic interaction and ion-exchange chromatography2007
- Author(s)
  Arakawa T, Tsumoto K, Nagase K, Ejima D
- Journal Title
  
  Protein Expr. Purif. 54
  
  Pages: 110-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] The N-terminal domain of elastin-binding protein of Staphylococcus aureus changes its secondary structure in a membrane-mimetic environment2007
- Author(s)
  Nakakido M, Tanaka Y, Tsumoto K.
- Journal Title
  
  J. Biochem. 142
  
  Pages: 131-134
- NAID
  10020096902
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A2007
- Author(s)
  Tsumoto K, Ejima D, Nagase K, Arakawa T.
- Journal Title
  
  J. Chromatogr. A 1154
  
  Pages: 81-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography.The cases of human interleukin-6 and activin-A2007
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  J.Chromatogr.A 1154
  
  Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] クロマトグラフィ-における凝集抑制と溶媒制御2006
- Author(s)
  津本, ら
- Journal Title
  
  生物工学会誌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Humanization of the bispecific EGFR×CD3 diabody and its efficacy as a potential clinical reagent2006
- Author(s)
  Ryutaro Asano, Yukiko Sone, Koki Makabe, Kouhei Tsumoto, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo, Izumi Kumagai
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages: 4036-4042
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] プロテインマニピュレーション : 蛋白質リフォールディングの最先端2006
- Author(s)
  津本浩平ら
- Journal Title
  
  化学と生物
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Efficient leukocyte IG-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer2006
- Author(s)
  Shiroishi M, Kuroki K, Ose T, Rasubala L, Shiratori I, Arase H, Tsumoto K, Kumagai I, Kohda D, Maenaka K.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 10439-10447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Entropically driven MHC class I recognition by human inhibitory receptor leukocyte Ig-like receptor B1 (LILRB1/ILT2/CD85j)2006
- Author(s)
  Shiroishi M., Kuroki K., Tsumoto K., Yokota A., Sasaki T., Amano K., Shimojima T., Shirakihara Y., Rasubala L., van der MerKohda D., Maenaka K.
- Journal Title
  
  J. Mol. Biol. 355
  
  Pages: 237-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] 蛋白質折りたたみの人工制御:プロテインマニピュレ-ション2006
- Author(s)
  津本, ら
- Journal Title
  
  未来材料
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Entropically driven MHC class I recognition by human inhibitory receptor leukocyte Ig-like receptor B1 (LILRBI/ILT2/CD85j)2006
- Author(s)
  Shiroishi M, Kuroki K, Tsumoto K, Yokota A, Sasaki T, Amano K, Shimojima T, Shirakihara Y, Rasubala L, van der Merwe PA, Kumagai I, Kohda D, Maenaka K.
- Journal Title
  
  J. Mol. Biol. 355
  
  Pages: 237-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] 抗原抗体相互作用における特異性・親和性創出機構の精密解析2006
- Author(s)
  津本浩平
- Journal Title
  
  生化学 (印刷中)
- NAID
  10017291659
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Efficient leIg-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer2006
- Author(s)
  Shiroishi M., Kuroki K., Ose T., Rasubala L., Shiratori I., Arase H., Tsumoto K., Kumagai I., Kohda D., Maenaka K.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 10439-10447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] 蛋白質折りたたみの人工制御 : プロテインマニピュレーション2006
- Author(s)
  津本浩平ら
- Journal Title
  
  未来材料
- Data Source
  KAKENHI-PROJECT-18038007
[Journal Article] Humanization of the bispecific epidermal growth or receptor x CD3 diabody and its efficacy as a potential clinical reagent,2006
- Author(s)
  Asano R., Sone Y., Makabe K., Tsumoto K., Hayashi H., Katayose Y., Unno M., Kudo T., Kumagai I.
- Journal Title
  
  Clin. Cancer Res. 12
  
  Pages: 4036-4042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] A novel "reverse screening" to identify refolding additives for activin-A2006
- Author(s)
  Daisuke Ejima, Kunio Ono, Kouhei Tsumoto*, Tsutomu Arakawa, Yuzuru Eto
- Journal Title
  
  Protein Expression and Purification 47
  
  Pages: 45-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] 蛋白質折りたたみの人工制御 : プロテインマニピュレーション2006
- Author(s)
  津本浩平ら
- Journal Title
  
  未来材料
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] 蛋白質リフォ-ルディングの最先端:プロテインマニピュレ-ション2006
- Author(s)
  津本, ら
- Journal Title
  
  化学と生物
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2ILIR2/ILT4/CD85d)2006
- Author(s)
  Shiroishi M, Kuroki K, Rasubala L, Tsumoto K, Kumagai I, Kurimoto E, Kato K, Kohda D, Maenaka K.
- Journal Title
  
  Proc Natl Acad Sci USA. 103
  
  Pages: 16412-16417
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Structural basis for reon of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)2006
- Author(s)
  Shiroishi M., Kuroki K., Rasubala L., Tsumoto K., Kumagai I., Kurimoto E., Kato K., Kohda D., Maenaka K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103
  
  Pages: 16412-16417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] クロマトグラフィーにおける凝集抑制と溶媒制御2006
- Author(s)
  津本浩平ら
- Journal Title
  
  生物工学会誌
- Data Source
  KAKENHI-PROJECT-18038007
[Journal Article] Review : Small molecule pharmacological chaperones : from thermodynamic stabilization to pharmaceutical drugs2006
- Author(s)
  Tsutomu Arakawa, Daisuke Ejima, Yoshiko Kita, Kouhei Tsumoto
- Journal Title
  
  Biochim. Biophis. Acta 1764
  
  Pages: 1677-1687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] 抗原抗体相互作用における特異性・親和性創出機構の精密解析2006
- Author(s)
  津本
- Journal Title
  
  生化学 78
  
  Pages: 93-109
- NAID
  10017291659
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] プロテインマニピュレーション : 蛋白質リフォールディングの最先端2006
- Author(s)
  津本浩平ら
- Journal Title
  
  化学と生物
- Data Source
  KAKENHI-PROJECT-18038007
[Journal Article] Aggregation suppression of proteins by arginine during thermal unfolding2006
- Author(s)
  Arakawa T, Kita Y, Ejima D, Tsumoto K, Fukada H.
- Journal Title
  
  Protein Pept Lett. 13
  
  Pages: 921-927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] クロマトグラフィーにおける凝集抑制と溶媒制御2006
- Author(s)
  津本浩平ら
- Journal Title
  
  生物工学会誌
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Daisuke EjimaBiotech Applications of Arginine : Novel Uses in Protein Production, Processing, Analysis, and Formulation2005
- Author(s)
  Tsutomu Arakawa, Kouhei Tsumoto
- Journal Title
  
  BioProcess International 3
  
  Pages: 20-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Tumor-directed lymphocyte-activating cytokines : refolding-based preparation of recombinant human interleukin-12 and an antibody variable domain-fused protein by additive-intoduced stepwise dialysis2005
- Author(s)
  Makabe K., Asano R., Ito T., Tsumoto K., Kudo T., Kumagai I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 328
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Arginine reduces non-specific protein binding in gel filtration2005
- Author(s)
  Daisuke Ejima, Ryosuke Yumioka, Tsutomu Arakawa, Kouhei Tsumoto
- Journal Title
  
  Journal of Chromatography A 1094
  
  Pages: 49-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Review: Why is Arginine Effective in Suppressing Aggregation?2005
- Author(s)
  Tsumoto, et. al.
- Journal Title
  
  Pep. Protein Lett. 12
  
  Pages: 613-619
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Review : Why is Arginine Effective in Suppressing Aggregation2005
- Author(s)
  Kohei Tsumoto, Daisuke Ejima, Yoshiko Kita, Tsutomu Arakawa
- Journal Title
  
  Pep. Protein Lett. 12
  
  Pages: 613-619
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Bioassistance for preferential immobilization of ZnO and synthesis of nanostrucrized ZnO forming a flower-type morphology2005
- Author(s)
  Mitsuo Umetsu, Masamichi Mizuta, Satoshi Ohara, Seiichi Takami, Hideki Watanabe, Kouhei Tsumoto, Izumi Kumagai, Tadafumi Adschiri
- Journal Title
  
  Advanced Materials 17
  
  Pages: 2571-2575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Characterization of Arginine as a Solvent Additive : A Halophilic Enzyme as a Model Protein2005
- Author(s)
  Matsujiro Ishibashi, Kohei Tsumoto, Daisuke Ejima, Tsutomu Arakawa, Masao Tokunaga
- Journal Title
  
  Pep. Protein Lett. 12
  
  Pages: 649-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Nondenaturing solubilization of beta2 microglobulin from inclusion bodies by L-arginine2005
- Author(s)
  Umetsu M., Tsumoto K., Nitta S., Adschiri T., Ejima D., Arakawa T., Kumagai I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 328
  
  Pages: 189-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Bioassisted room-temperature immobilization and mineralization of zinc oxide -The structural ordering of ZnO nanoparticles into a flower-type morphorogy2005
- Author(s)
  Umetsu M., Mizuta M., Tsumoto K., Ohara S., Takami S., Watanabe H., Kumagai I., Adschiri T.
- Journal Title
  
  Adv. Mater. 17
  
  Pages: 2571-2575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Review : Why is Arginine Effective in Suppressing Aggregation?2005
- Author(s)
  Kohei Tsumoto et al.
- Journal Title
  
  Pep.Protein Lett. 12
  
  Pages: 613-619
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography2005
- Author(s)
  Daisuke Ejima, Ryosuke Yumioka, Kouhei Tsumoto, Tsutomu Arakawa
- Journal Title
  
  Analytical Biochemistry 345
  
  Pages: 250-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Crystal structure of the hypothetical protein ST2072 from Sulfolobus tokodaii2005
- Author(s)
  Yoshikazu Tanaka, Kouhei Tsumoto, Eiki Tanabe, Yoshiaki Yasutake, Naoki Sakai, Min Yao, Isao Tanaka, Izumi Kumagai
- Journal Title
  
  Proteins Structure Function and Bioinformatics 61
  
  Pages: 1127-1131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Mini Review : Is arginine a protein-denaturant2005
- Author(s)
  Matsujiro Ishibashi, Kouhei Tsumoto, Masao Tokunaga, Daisuke Ejima, Yoshiko Kita and Tsutomu Arakawa
- Journal Title
  
  Protein Exp. Purif. 42
  
  Pages: 1-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Journal Article] Why is Arginine Effective in Suppressing Aggregation?2005
- Author(s)
  Kohei Tsumoto, et al.
- Journal Title
  
  Pep.Protein Lett. 12
  
  Pages: 613-619
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Glorioso J.C., Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule2005
- Author(s)
  Nakano K., Asano R., Tsumoto K., Kwon H., Goins W.F., Kumagai I., Cohen J.B.
- Journal Title
  
  Mol. Ther. 11
  
  Pages: 617-626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Pathway to insoluble aggregates on the refolding of a single-chain Fv antibody: morphological changes of aggregated protein onrefolding2004
- Author(s)
  Umetsu M., Ashish K., Tsumoto K., Kumagai I.
- Journal Title
  
  Chem. Lett. (Jpn.) 33
  
  Pages: 1600-1601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments,2004
- Author(s)
  Nagumo Y., Oguri H., Tsumoto K., Shindo Y., Hirama M., Tsumuraya T., Fujii I., Tomioka Y., Mizugaki M., Kumagai I.
- Journal Title
  
  J. Immunol. Meth. 289
  
  Pages: 137-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification.2004
- Author(s)
  Kouhei Tsumoto, et al.
- Journal Title
  
  Biotechnology Progress 20
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-14704006
[Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification.2004
- Author(s)
  Kouhei Tsumoto, et al.
- Journal Title
  
  Biotechnology Progress 20
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-16041204
[Journal Article] A highly effectivbispecific diabody for cancer immunotherapy : cure of xenografted tumors by bispecific diabody and T-LAK cells2004
- Author(s)
  Hayashi H., Asano R., Tsumoto K., Katayose Y., Suzuki M., Unno M., Kodama H., Takemura S., Yoshida H., Makabe K., Imai K., Matsuno S., Kumagai I., Kudo T.
- Journal Title
  
  Cancer Immunol. Immunother. 53
  
  Pages: 497-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Fucose depletion from human IgG1 oligosaccharide enhancbinding enthalpy and association rate between IgG1 and FcγRIIIa2004
- Author(s)
  Okazaki A., Shoji-Hosaka E., Nakamura K., Wakitani M., Uchida K., Kakita S., Tsumoto K., Kumagai I., Shitara K.
- Journal Title
  
  J. Mol. Biol. 336
  
  Pages: 1239-1249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16106011
[Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification2004
- Author(s)
  Kouhei Tsumoto, et al.
- Journal Title
  
  Biotechnology Progress 20
  
  Pages: 301-308
- Data Source
  KAKENHI-PROJECT-16106011
[Patent] 金属ナノクラスター2021
- Inventor(s)
  鈴木康介, 山口和也,(中略), 津本浩平, 中木戸誠
- Industrial Property Rights Holder
  鈴木康介, 山口和也,(中略), 津本浩平, 中木戸誠
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-141495
- Filing Date
  2021
- Acquisition Date
  2022
- Data Source
  KAKENHI-PLANNED-19H05766
[Patent] 全身性炎症反応症候群の治療又は予防剤2013
- Inventor(s)
  浜窪隆雄、津本浩平
- Industrial Property Rights Holder
  国立大学法人東京大学、学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2013
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-25220205
[Patent] 抗体改変による疾患部位特異的な診断薬・治療薬の集積法2009
- Inventor(s)
  浜窪隆雄、津本浩平, 他
- Industrial Property Rights Holder
  東大TLO
- Filing Date
  2009-04-09
- Overseas
- Data Source
  KAKENHI-PROJECT-21360398
[Patent] 抗体改変による疾患部位特異的な診断薬・治療薬の集積法2009
- Inventor(s)
  浜窪隆雄、津本浩平, 他
- Industrial Property Rights Holder
  東大TLO
- Filing Date
  2009-04-09
- Data Source
  KAKENHI-PROJECT-21360398
[Patent] 新規なダイアボディ型二重特異性抗体2006
- Inventor(s)
  熊谷泉, 工藤俊雄, 津本浩平, 浅野竜太郎
- Industrial Property Rights Holder
  東北テクノアーチ
- Filing Date
  2006-05-19
- Data Source
  KAKENHI-PROJECT-16106011
[Presentation] University of Tokyo C2CIMM / ESPCI - PSL University Joint Symposium,2024
- Author(s)
  Ujiie K, Tanabe A, Nagatoishi S, Tsumoto K
- Organizer
  University of Tokyo C2CIMM / ESPCI - PSL University Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Supercharging antibodies to control the physicochemical properties2024
- Author(s)
  Kasahara K、Kuroda D、Jose M. M. Caaveiro、Yamawaki T、Nakakido M、Nagatoishi S、Tsumoto K
- Organizer
  University of Tokyo C2CIMM / ESPCI - PSL University Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 膜蛋白質Glut1の動態解明を指向した部位特異的抗体の開発2023
- Author(s)
  住川太一, 中木戸誠, 黒田大祐, 津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Unique molecular recognition mechanisms of β-hairpin CDR3 of an anti-HigB2 VHH antibody2023
- Author(s)
  Yamamoto K, Nakakido M, Kuroda D, Nagatoishi S, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 新技術と情報科学による新時代の創薬モダリティ2023
- Author(s)
  津本浩平
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] シナプスオーガナイザーMDGA1に対するナノボディの取得と人工シナプスコネクターへの応用2023
- Author(s)
  横尾尚典、中木戸誠、松田恵子、木下清晶、柚﨑通介、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] シナプスオーガナイザーMDGA1に対するナノボディの取得と人工シナプスコネクターの設計2023
- Author(s)
  横尾尚典、中木戸誠、松田恵子、木下清晶、柚﨑通介、津本浩平
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Generation of Site-specific Antibodies to a Membrane Protein by Using a Scaffold Protein2023
- Author(s)
  Sumikawa T、Nakakido M、Kuroda D、Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 化膿レンサ球菌の糖結合蛋白質SPs1696の機能を阻害する抗体の探索2023
- Author(s)
  山脇つくし、中木戸誠、木下清晶、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Proposal for the model of aHUS pathogenesis caused by anti-CFH autoantibodies based on the functional analysis of novel antibodies2023
- Author(s)
  Yokoo T, Tanabe A, Nakakido M, Nagatoishi S, Jose M. M. Caaveiro, Yoshida Y, Ikeda Y, Nangaku M, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Characterization of modulation system of multi-specific interactions of PRELP with intrinsically weak affinity through ECM localization2023
- Author(s)
  小菅啓史、中木戸誠、スサーナデベガ、長門石曉、福田哲也、板東泰彦、大沼信一、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40抗体のエピトープと速度論的性質に基づくアゴニスト活性デザイン2023
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第17回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 次世代抗体医薬品への期待2023
- Author(s)
  津本浩平
- Organizer
  第33回日本リウマチ学会関東支部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] An Endothelial Cell-Pericytes Coculture to Model Abnormal Angiogenesis in vitro2023
- Author(s)
  Susana de Vega, Tsumoto K, Okada Y
- Organizer
  3D Cell Culture and Organoid Modeling 2023, Oxford Global
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Molecularly linked antibodies inhibit the function of metal binding proteins2023
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  Library Design for Protein Engineerin
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Fab抗体とNanobodyのスーパーチャージによる物性・機能改質2023
- Author(s)
  笠原慶亮、黒田大祐、カアベイロホセ、山脇つくし、氏家寛、中木戸誠、長門石曉、津本浩平
- Organizer
  第2回　日本抗体学会学術大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 細胞外マトリクスへの局在を介した多重特異性蛋白質PRELPの弱い相互作用の制御機構の解析2023
- Author(s)
  小菅啓史、中木戸誠、スサーナデベガ、長門石曉、福田哲也、板東泰彦、大沼信一、津本浩平
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Elucidation and control of physicochemical properties of antibodies by supercharging of variable regions2023
- Author(s)
  Kasahara K, Kuroda D, Nagatoishi S, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Fab抗体とNanobodyのスーパーチャージによる物性・機能改質2023
- Author(s)
  笠原慶亮、黒田大祐、カアベイロホセ、山脇つくし、氏家寛、中木戸誠、長門石曉、津本浩平
- Organizer
  第2回日本抗体学会学術大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] In silico design of cross-reactive antibodies which incorporates antigen's dynamics2023
- Author(s)
  安田佳生、黒田大祐、佐々木慈英、中木戸誠、松長遼、橋口隆生、津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] シナプスオーガナイザーMDGA1に対するナノボディの取得と人工シナプスコネクターへの応用2023
- Author(s)
  横尾尚典、中木戸誠、松田恵子、木下清晶, 柚﨑通介, 津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 膜蛋白質Glut1の動態解明を指向した部位特異的抗体の開発2023
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40アゴニスト抗体の結合部位と速度論的性質に基づく受容体認識及びシグナル制御機構の考察2023
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Thermodynamic analysis of Fv-supercharged antibody-antigen interactions and control of interaction parameters2023
- Author(s)
  笠原慶亮、黒田大祐、カアベイロホセ、長門石曉、津本浩平
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 可変領域の表面電荷改変による抗体の安定性・結合親和性制御メカニズムの解明2023
- Author(s)
  笠原慶亮、黒田大祐、長門石曉、津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 分子連結した抗体は金属結合蛋白質の機能を阻害する2023
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Thermodynamic analysis of Fv-supercharged antibody-antigen interactions and control of interaction parameters2023
- Author(s)
  笠原慶亮、黒田大祐、カアベイロホセ、長門石曉、津本浩平
- Organizer
  第61回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体FR2残基による特徴的な親和性-安定性トレードオフ機構の解明2023
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、津本浩平
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Development of a covalently-binding antibody mimetics2023
- Author(s)
  徳永悠希、松長遼、津本浩平
- Organizer
  Library Design for Protein Engineering
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] VHH抗体における37番残基の相互作用寄与メカニズムの検証2023
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、津本浩平
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Proposal for the model of aHUS pathogenesis caused by anti-CFH autoantibodies based on the functional analysis of novel antibodies2023
- Author(s)
  Yokoo T, Tanabe A, Nakakido M, Nagatoishi S, Jose M. M. Caaveiro, Yoshida Y, Ikeda Y, Nangaku M, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Analytical Solutions for Research, Development & CMC of Novel Modalities of Drugs (I) ～Comprehensive Understanding of Molecular Structure, Dynamics and Function2023
- Author(s)
  津本浩平,長門石曉
- Organizer
  PITTCON 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 可変領域スーパーチャージ抗体の安定性・結合親和性とその溶媒依存性の解明2023
- Author(s)
  笠原慶亮、黒田大祐、長門石曉、津本浩平
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 抗OX40アゴニスト抗体の受容体認識およびシグナル制御機構に関する速度論的特性2023
- Author(s)
  氏家　寛、田部亜季、長門石曉、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Elucidation and control of physicochemical properties of antibodies by supercharging of variable regions2023
- Author(s)
  Kasahara K, Kuroda D, Nagatoishi S, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿レンサ球菌の糖結合蛋白質SPs1696の機能を阻害する抗体の探索2023
- Author(s)
  山脇つくし、中木戸誠、木下清晶、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 相互作用データのハイスループットな収集による抗体特異性制御残基の特定2023
- Author(s)
  稲垣万優子、松長遼、奥村繁、丸山俊昭、Entzminger Kevin、津本浩平
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] ハイスループット蛋白質熱安定性データ収集系の開発2023
- Author(s)
  伊藤沙衣、松長遼、中木戸誠、河村大輔、加藤洋人、石川俊平、津本浩平
- Organizer
  第61回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Characterization of modulation system of multi-specific interactions of PRELP with intrinsically weak affinity through ECM localization2023
- Author(s)
  小菅啓史、中木戸誠、スサーナデベガ、長門石曉、福田哲也、板東泰彦、大沼信一、津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] In silico design of cross-reactive antibodies which incorporates antigen & dynamics2023
- Author(s)
  安田佳生、黒田大祐、佐々木慈英、中木戸誠、松長遼、橋口隆生、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 第23回日本蛋白質科学会年会2023
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  令和5年度生命金属科学夏の合宿
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Unique molecular recognition mechanisms of β-hairpin CDR3 of an anti-HigB2 VHH antibody2023
- Author(s)
  Yamamoto K、Nakakido M、Kuroda D、Nagatoishi S、Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Development of high-throughput data collecting system for thermal stability of protein2023
- Author(s)
  伊藤沙衣、松長遼、中木戸誠、河村大輔、加藤洋人、石川俊平、津本浩平
- Organizer
  Library Design for Protein Engineering
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 抗体医薬の技術革新　～多様化する抗体薬のメカニズムを解き明かす～2023
- Author(s)
  津本浩平
- Organizer
  第20回日本臨床腫瘍学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] T細胞活性化因子OX40を制御する合理的なアゴニスト抗体設計指針の提案2023
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] VHHのβ-hairpin型CDR3解明のためのNb8抗体に関する精密解析2023
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHHのβ-hairpin型CDR3解明のためのNb8抗体に関する精密解析2023
- Author(s)
  山本晃一, 中木戸誠, 黒田大祐, 長門石曉, 津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Fab抗体とNanobodyのスーパーチャージによる物性・機能改質2023
- Author(s)
  笠原慶亮、黒田大祐、カアベイロホセ、山脇つくし、氏家寛、中木戸誠、長門石曉、津本浩平
- Organizer
  第2回日本抗体学会学術大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 金属結合蛋白質MtsAに対する分子連結型機能制御抗体の開発2023
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] Generation of Site-specific Antibodies to a Membrane Protein by Using a Scaffold Protein2023
- Author(s)
  Sumikawa T, Nakakido M, Kuroda D, Tsumoto K
- Organizer
  The 37th Annual Symposium of the Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 固定化単ドメイン抗体の結合活性と変性剤耐性解析2023
- Author(s)
  平尾篤紀、長門石曉、池内江美奈、山脇つくし、森千夏、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] An Endothelial Cell-Pericytes Coculture to Model Abnormal Angiogenesis in vitro2023
- Author(s)
  Susana de Vega, Tsumoto K, Okada Y
- Organizer
  3D Cell Culture and Organoid Modeling 2023_Oxford Global
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40アゴニスト抗体の受容体認識およびシグナル制御機構に関する速度論的特性2023
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 個性を活かしたタンパク質デザイン戦略2023
- Author(s)
  松長遼、津本浩平
- Organizer
  第1回 MA-T学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 物理化学的解析に基づくメチル化抗原特異的認識抗体の親和性向上2023
- Author(s)
  三浦優花、横尾尚典、中木戸誠、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 可変領域の表面電荷改変による抗体の安定性・結合親和性制御メカニズムの解明2023
- Author(s)
  笠原慶亮、黒田大祐、長門石曉、津本浩平
- Organizer
  第23回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] シナプスオーガナイザーMDGA1に対するナノボディを用いた人工シナプスコネクターの創出2023
- Author(s)
  横尾尚典、中木戸誠、松田恵子、木下清晶、柚﨑通介、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 細胞外マトリクスへの局在を介した多重特異性蛋白質PRELPの弱い相互作用の制御機構の解析2023
- Author(s)
  小菅啓史、中木戸誠、スサーナデベガ、長門石曉、福田哲也、板東泰彦、大沼信一、津本浩平
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] A群レンサ球菌の表層蛋白質の機能を阻害する抗体の探索2023
- Author(s)
  山脇つくし、中木戸誠、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第96回　日本細菌学会総会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ハイスループット蛋白質熱安定性データ収集系の開発2023
- Author(s)
  伊藤沙衣、松長遼、中木戸誠、河村大輔、加藤洋人、石川俊平、津本浩平
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K21343
[Presentation] 腫瘍抑制蛋白質PRELPのマルチバレント相互作用を介した機能制御2023
- Author(s)
  中木戸誠, 小菅啓史, 長門石曉, 福田哲也, 板東泰彦, Susana de Vega, 大沼信一, 津本浩平
- Organizer
  第96回　日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40抗体のエピトープと速度論的性質に基づくアゴニスト活性デザイン2023
- Author(s)
  氏家　寛、田部亜季、長門石曉、津本浩平
- Organizer
  第17回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ハイスループットな抗体変異体スクリーニング系の構築2022
- Author(s)
  稲垣万優子、松長遼、奥村繁、丸山俊昭、Entzminger K、津本浩平
- Organizer
  第95回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Commitment to drug development in the center for drug design research(CDDR) 創薬デザイン研究センター（CDDR)の取り組み2022
- Author(s)
  津本浩平
- Organizer
  日本組織培養学会第94回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 様々なIgG型抗体に関するFcγRIIIaの物理化学的相互作用解析2022
- Author(s)
  長門石曉, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌のマルトース/マルトデキストリン結合蛋白質SPs0871の機能を阻害するVHH抗体による基質結合阻害機構の解明2022
- Author(s)
  山脇つくし、中木戸誠、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Commitment to drug development in the center for drug design research(CDDR) 創薬デザイン研究センター（CDDR)の取り組み2022
- Author(s)
  津本浩平
- Organizer
  日本組織培養学会第94回大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 表面電荷改変抗体のコロイド安定性・結合親和性とその溶媒依存性の解析2022
- Author(s)
  笠原慶亮、黒田大祐、長門石曉、津本浩平
- Organizer
  第60回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Molecular Basis of Contribution of Intramolecular Interactions between Complementarity Determining Region 3 (CDR3) and Framework Region on Biophysical Properties in Camelid Single-Domain Antibody2022
- Author(s)
  Kinoshita S, Nakakido M, Kuroda D, Jose M. M. Caaveiro, Tsumoto K
- Organizer
  The 36th Annual Symposium of The Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 抗OX40アゴニスト小唄の相互作用に関する速度論的研究2022
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Monomer-Dimer Equilibrium of a Tumor Suppressor PRELP Driven by the Hydrophobic Interface Regulates the Multi-Specific Interactions2022
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Development of molecular inhibitors against iron transporters from Streptococcos pyogenes2022
- Author(s)
  Nakakido M, Asano R, Fernandez P.J., Takeuchi M, Aikawa C, Nakagawa I, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Acquisition of novel VHH antibodies to synaptic organizers for application to molecular imaging2022
- Author(s)
  横尾尚典、中木戸誠、松田恵子、柚﨑通介、津本浩平
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] VHH抗体の概要と医療応用の可能性2022
- Author(s)
  津本浩平
- Organizer
  第32回日本リウマチ学会関東支部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Physicochemical analysis of receptor recognition mechanism of anti-OX40 agonist antibodies2022
- Author(s)
  氏家寛、田部亜季，長門石曉，津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Superchargingデザインは溶媒選択により抗体の物性を制御できる2022
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Rubredoxin A from M. tuberculosis2022
- Author(s)
  Sushko T, J.M.M. Caaveiro, Nagatoishi S, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Functional Evaluation of Molecule-Linked Antibodies against Metal-Binding Protein of Streptococcus pyogenes, MtsA2022
- Author(s)
  Asano R, Nakakido M, Takeuchi M, Aikawa C, Nakagawa I, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Molecular Basis of Contribution of Intramolecular Interactions between Complementarity Determining Region 3 (CDR3) and Framework Region on Biophysical Properties in Camelid Single-Domain Antibody2022
- Author(s)
  Kinoshita S, Nakakido M, Kuroda D, Jose M. M. Caaveiro, Tsumoto K
- Organizer
  The Protein Society 36th Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Functional Evaluation of Molecule-Linked Antibodies against Metal-Binding Protein of Streptococcus pyogenes, MtsA2022
- Author(s)
  淺野　梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  10th Asian Biological Inorganic Chemistry Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] FcγRIIIa受容体の固定化系と溶液系における抗体認識機構の解明2022
- Author(s)
  長門石曉、木下清晶, 黒田大祐, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌のマルトース/マルトデキストリン結合蛋白質SPs0871の機能を阻害するVHH抗体による基質結合阻害機構の解明2022
- Author(s)
  山脇つくし、中木戸誠、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40アゴニスト小唄の相互作用に関する速度論的研究2022
- Author(s)
  氏家寛、田部亜季，長門石曉，津本浩平
- Organizer
  第16回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 新規抗体の機能解析に基づく抗CFH自己抗体によるaHUS発症機構モデルの提案2022
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、カアベイロホセ、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Development of Molecular Inhibitors against Iron Transporters from Streptococcus pyogenes2022
- Author(s)
  Nakakido M, Asano R, Fernandez P.J., Takeuchi M, Aikawa C, Nakagawa I, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Development of new antimicrobial strategies against the iron uptake systems of Streptococcus pyogenes2022
- Author(s)
  Fernandez J, Caaveiro MM J, Nakakido M, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 創薬モダリティ開発を加速させる相互作用解析支援と技術開発2022
- Author(s)
  津本浩平
- Organizer
  BINDSシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌細胞表面由来金属結合タンパク質に対する機能阻害剤探索2022
- Author(s)
  中木戸誠、淺野梨紗、竹内美結、伊藤翔、相川知宏、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Development of Humanized Single-Domain Antibody Synthetic Libraries Based on Physicochemical Analyses2022
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] A群レンサ球菌の表層蛋白質の機能を阻害する抗体の探索2022
- Author(s)
  山脇つくし、中木戸誠、相川知宏、カアベイロホセ、中川一路、津本浩平
- Organizer
  第96回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] モダリティ創薬と抗体2022
- Author(s)
  津本浩平
- Organizer
  第72回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] In silico design of cross-reactive antibodies binding to SARS-CoV and SARS-CoV-2 spike RBDs2022
- Author(s)
  安田佳生、黒田大祐、佐々木慈英、中木戸誠、松長遼、橋口隆生、津本浩平
- Organizer
  第60回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌細胞表面由来金属結合タンパク質に対する機能阻害剤探索2022
- Author(s)
  中木戸誠、淺野梨紗、竹内美結、伊藤翔、相川知宏、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] In silico design of cross-reactive antibodies binding to SARS-CoV and SARS-CoV-2 spike RBDs2022
- Author(s)
  安田佳生、黒田大祐、佐々木慈英、中木戸誠、松長遼、橋口隆生、津本浩平
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Identification and validation of multi-specific interactions of a tumor suppressor protein PRELP2022
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  The 17th International Symposium of the Institute Network for Biomedical Sciences & International Symposium on Tumor Biology in Kanazawa 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Characterization of the regulatory system of multi-specific interactions of a novel tumor suppressor PRELP through the hydrophobicity-driven dimerization2022
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S,Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Rubredoxin A from M. tuberculosis2022
- Author(s)
  Sushko T, J.M.M. Caaveiro, Nagatoishi S, Tsumoto K
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体の概要と医療応用の可能性2022
- Author(s)
  津本浩平
- Organizer
  第32回日本リウマチ学会関東支部学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2022
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] モダリティ創薬と抗体2022
- Author(s)
  津本浩平
- Organizer
  第72回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Monomer-Dimer Equilibrium of a Tumor Suppressor PRELP Driven by the Hydrophobic Interface Regulates the Multi-Specific Interactions2022
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗体創薬のための物性解析：これまでとこれから2022
- Author(s)
  長門石曉、津本浩平
- Organizer
  第1回日本抗体学会設立記念学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] CDR-Graftingによるヒト化VHHの物性機能解析に基づくヒト化VHH人工合成ライブラリ構築2022
- Author(s)
  木下清晶、中木戸誠、黒田大祐、Jose M.M. Caaveiro、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 表面電荷改変抗体のコロイド安定性・結合親和性とその溶媒依存性の解析2022
- Author(s)
  笠原慶亮、黒田大祐、長門石曉、津本浩平
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 足場蛋白質を活用した特定のエピトープ領域に対する抗体取得2022
- Author(s)
  住川　太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  日本化学会生体機能関連化学会若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌由来金属結合蛋白質MtsAに対するバイパラトピック抗体の設計と機能評価2022
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Physicochemical analysis of receptor recognition mechanism of anti-OX40 agonist antibodies2022
- Author(s)
  氏家寛、田部亜季，長門石曉，津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌由来金属結合蛋白質MtsAに対するバイパラトピック抗体の設計と機能評価2022
- Author(s)
  淺野梨紗、中木戸誠、竹内美結、相川知宏、中川一路、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Identification and validation of multi-specific interactions of a tumor suppressor protein PRELP2022
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  The 17th International Symposium of the Institute Network for Biomedical Sciences & International Symposium on Tumor Biology in Kanazawa 2022 (Hybrid Conference)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] ハイスループットな抗体変異体スクリーニング系の構築2022
- Author(s)
  稲垣万優子、松長遼、奥村繁、丸山俊昭、Entzminger K、津本浩平
- Organizer
  第95回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Acquisition of novel VHH antibodies to synaptic organizers for application to molecular imaging2022
- Author(s)
  横尾尚典、中木戸誠、松田恵子、柚﨑通介、津本浩平
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] FcγRIIIa受容体の固定化系と溶液系における抗体認識機構の解明2022
- Author(s)
  長門石曉、木下清晶, 黒田大祐, 小菅啓史, 木吉真人, 石井明子, 寺尾陽介, 井出輝彦, 津本浩平
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] CDR-Graftingによるヒト化VHHの物性機能解析に基づくヒト化VHH人工合成ライブラリ構築2022
- Author(s)
  木下　清晶、中木戸誠、黒田大祐、Jose M.M. Caaveiro、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Superchargingデザインは溶媒選択により抗体の物性を制御できる2022
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第22回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿レンサ球菌のマルトース/マルトデキストリン結合蛋白質SPs0871の特性評価及びその機能を阻害するVHH抗体の探索2021
- Author(s)
  山脇つくし、中木戸誠、相川知宏、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021
- Author(s)
  中木戸誠、竹内美結、長門石曉、相川知宏、中川一路、津本浩平
- Organizer
  第94回　日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Drug Delivery System技術開発へのタンパク質工学の貢献：現状と今後2021
- Author(s)
  津本浩平
- Organizer
  立命館大学　製剤技術研究コンソーシアム　2021年度　第4回研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 蛋白質科学が社会へ与えるインパクト：AMED-BINDSから次のステージへ2021
- Author(s)
  津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿レンサ球菌のマルトース/マルトデキストリン結合蛋白質SPs0871の特性評価及びその機能を阻害するVHH抗体の探索2021
- Author(s)
  山脇つくし、中木戸誠、相川知宏、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021
- Author(s)
  中木戸誠、竹内美結、長門石曉、相川知宏、中川一路、津本浩平
- Organizer
  第94回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Interaction analysis between small-molecules and proteins using HDX-MS in physicochemical screening2021
- Author(s)
  長門石曉,　津本浩平
- Organizer
  第69回質量分析総合討論会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Proteomic Identification and Validation of Novel Interactions of a Tumor Suppressor PRELP with the Growth Factor Receptors IGFI-R and p75NTR2021
- Author(s)
  Hirofumi Kosuge, Makoto Nakakido, Satoru Nagatoishi, Tetsuya Fukuda, Yasuhiko Bando, Shin-ichi Ohnuma, Kouhei Tsumoto
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、カアベイロホセ、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿連鎖球菌由来金属トランスポーターに対する機能阻害剤探索2021
- Author(s)
  中木戸誠、竹内美結、伊藤翔、相川知宏、長門石曉、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 次世代抗体開発と物理化学2021
- Author(s)
  津本浩平
- Organizer
  有機合成化学協会「ニューモダリティと有機合成化学」第6回勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] VHH抗体の構造特徴を利用したβ-hairpin型ペプチド設計手法の探索2021
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2021
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 膜蛋白質Glut1の細胞外領域を認識する抗体取得法の提案2021
- Author(s)
  住川　太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗OX40抗体の受容体機能制御に関わる分子メカニズム解明2021
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Proteomic Identification and Validation of Novel Interactions of a Tumor Suppressor PRELP with the Growth Factor Receptors IGFI-R and p75NTR2021
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 膜蛋白質の膜外領域を認識する抗体の取得2021
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 膜蛋白質Glut1の細胞外領域を認識する抗体取得法の提案2021
- Author(s)
  住川　太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] A novel homodimerization mechanism of LI-cadherin2021
- Author(s)
  Yui A, Caaveiro J.M.M, Kuroda D, Nakakido M, Nagatoishi S, Maruno T, Uchiyama S, Tsumoto K
- Organizer
  The Protein Society 35th Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Physicochemical studies of mutations in framework regions of VHH focusing on intramolecular interactions with CDR32021
- Author(s)
  木下清晶、中木戸誠,、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 次世代医薬品開発と蛋白質科学2021
- Author(s)
  津本浩平
- Organizer
  CIBoG特別
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Acquisition of novel VHH antibodies to synaptic organizers for application to molecular imaging2021
- Author(s)
  横尾尚典、中木戸誠、柚﨑通介、津本浩平
- Organizer
  第44回日本神経科学大会　CJK 第１回国際会議
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] How SNPs in LI-cadherin gene increases the risk of cancer metastasis2021
- Author(s)
  Yui A, Kikuchi C, Goda S, Kudo S, Akiba H, Nakakido M, Kuroda D, Nagatoishi S, Arai O, Iwanari H, Hamakubo T, Tsumoto K
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 膜蛋白質の膜外領域を認識する抗体の取得2021
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Physicochemical studies of mutations in framework regions of VHH focusing on intramolecular interactions with CDR32021
- Author(s)
  木下清晶、中木戸誠,、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] プロテオーム解析に基づく腫瘍抑制蛋白質PRELPと膜蛋白質の新規相互作用探索と機能解析2021
- Author(s)
  小菅啓史、中木戸誠、長門石曉、福田哲也、板東泰彦、大沼信一、津本浩平
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿連鎖球菌由来金属トランスポーターに対する機能阻害剤探索2021
- Author(s)
  中木戸誠、竹内美結、伊藤翔、相川知宏、長門石曉、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] A novel homodimerization mechanism of LI-cadherin2021
- Author(s)
  Anna yui, Jose M. M. Caaveiro, Daisuke Kuroda, Makoto Nakakido, Satoru Nagatoishi, Takahiro Maruno, Susumu Uchiyama, and Kouhei Tsumoto
- Organizer
  The Protein Society 35th Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗体工学のモダリティ創薬への貢献2021
- Author(s)
  津本浩平
- Organizer
  日本プロテオーム学会　2021年大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 抗体表面への正荷電残基変異導入による抗体のpH非依存的な熱安定性獲得機構2021
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗体の抗原特異性創出機構の解明と親和性向上指針の提案2021
- Author(s)
  津本浩平
- Organizer
  CBI学会2021大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021
- Author(s)
  発表者名：横尾尚典、田部亜季、中木戸誠、長門石曉、カアベイロホセ、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Analysis of the molecular mechanisms involved in the recognition of antigen and the regulation of function by antibodies2021
- Author(s)
  氏家寛、田部亜季、長門石曉、津本浩平
- Organizer
  第44回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 抗体工学のモダリティ創薬への貢献2021
- Author(s)
  津本浩平
- Organizer
  日本プロテオーム学会　2021年大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 抗体表面への正荷電残基変異導入による抗体のpH非依存的な熱安定性獲得機構2021
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 膜蛋白質の膜外領域を認識する抗体の取得2021
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] VHHにおけるCDR3-Framework region間分子内相互作用に着目したフレームワーク改変の物理化学的解析2021
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] モダリティ創薬研究におけるITC2021
- Author(s)
  津本浩平
- Organizer
  MicroCal ITCワークショップ2021、WEBセミナー
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体の構造特徴を利用したβ-hairpin型ペプチド設計手法の探索2021
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] モダリティ創薬研究におけるITC2021
- Author(s)
  津本浩平
- Organizer
  MicroCal ITCワークショップ2021
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHHにおけるCDR3-Framework region間分子内相互作用に着目したフレームワーク改変の物理化学的解析2021
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Acquisition of novel VHH antibodies to synaptic organizers for application to molecular imaging2021
- Author(s)
  横尾尚典、中木戸誠、柚﨑通介、津本浩平
- Organizer
  第44回日本神経科学大会　CJK 第１回国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHHにおけるCDR3-Framework region間分子内相互作用に着目したフレームワーク改変の物理化学的解析2021
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] バイオスペリア時代の抗体エンジニアリング2020
- Author(s)
  津本浩平
- Organizer
  BioJapan 2020
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Obtaining antibodies against Staphyloccus aureus2020
- Author(s)
  Valenciano　S, Sandra Bellido, Jose M.M. Caaveiro, Nakakido M, Nagatoishi S, Tsumoto K
- Organizer
  2020年度　医科学研究所G2発表会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第48回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 計算デザイン Supercharging 抗体の物性機能解析2020
- Author(s)
  笠原慶亮、黒田大祐、河出来時、田部亜季、長門石曉、津本浩平
- Organizer
  第48回　構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 抗体医薬と蛋白質物性：製剤技術研究への期待2020
- Author(s)
  津本浩平
- Organizer
  製剤機械技術学会30周年記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 蛋白質-蛋白質間相互作用の速度論的制御に基づくP-カドヘリンの細胞接着形成阻害2020
- Author(s)
  妹尾暁暢、長門石曉、黒田大祐、伊藤翔、上野剛、齋藤雄太朗、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第14回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成VHHにおける分子挙動の解析2020
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Inhibition of P-cadherin-mediated cell contact formation through the kinetic effect of chemical fragment2020
- Author(s)
  妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成VHHにおける分子挙動の解析2020
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 物理化学的アプローチによる低分子阻害剤の探索および抗体阻害剤の開発2020
- Author(s)
  中木戸誠、相川知宏、長門石曉、妹尾暁暢、竹内美結、星野将人、下村拓矢、カアベイロホセ、中川一路、津本浩平
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 病原性微生物における金属動態の分子機構解析2020
- Author(s)
  津本浩平
- Organizer
  2020年度iBIX-JAXA-KEK物構研-QST合同研究会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 日米セッション/先端創薬への分析ソリューション-その先にあるもの（Beyond Biopharma Analysis）2020
- Author(s)
  津本浩平
- Organizer
  JASIS WebExpoライフサイエンスイノベーションゾーン企画
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 抗体医薬と蛋白質物性：製剤技術研究への期待2020
- Author(s)
  津本浩平
- Organizer
  製剤機械技術学会30周年記念大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 蛋白質-蛋白質間相互作用の速度論的制御に基づくP-カドヘリンの細胞接着形成阻害2020
- Author(s)
  妹尾暁暢、長門石曉、黒田大祐、伊藤翔、上野剛、齋藤雄太朗、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第14回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 病原性微生物における金属動態の分子機構解析2020
- Author(s)
  津本浩平
- Organizer
  2020年度iBIX-JAXA-KEK物構研-QST合同研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Molecular basis of increased risk of colorectal cancer metastasis caused by SNPs in LI-cadherin2020
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、丸野孝浩、内山進、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Application of β-hairpin structure of VHH CDR3 for peptide designs2020
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  2020年度　医科学研究所G2発表会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 新興・再興感染症対策への抗体エンジニアリングの貢献2020
- Author(s)
  津本浩平
- Organizer
  ナノメディシン交流協会臨時会議「コロナウィルス感染症とナノメディシン」
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Structural analysis of a peptide fragment grafted onto the Adhiron scaffold2020
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Proteomic Identification And Validation Of New Interactions Of Novel Tumor Suppressor PRELP With Membrane Proteins2020
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020
- Author(s)
  竹内美結、中木戸誠、長門石曉、河出来時、相川知宏、中川一路、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体β-hairpin型CDR3を利用したペプチド設計手法の探索2020
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Molecular Basis for Heme Extraction of the Antimicrobial Target IsdH from Staphylococcus aureus from Human Hemoglobin2020
- Author(s)
  S. Valenciano, V. T. Nhuan, M. Nakakido, J. M.M. Caaveiro, K. Tsumoto
- Organizer
  Biophysical Society 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 相互作用の熱力学的解析とCOVID-192020
- Author(s)
  津本浩平
- Organizer
  CBI学会2020年大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020
- Author(s)
  竹内美結、中木戸誠、長門石曉、河出来時、相川知宏、中川一路、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Inhibition of P-cadherin-mediated cell contact formation through the kinetic effect of chemical fragment2020
- Author(s)
  妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] The Molecular Basis of How SNP in LI-cadherin Affected Cancer Metastasis2020
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] バイオスペリア時代の抗体エンジニアリリング2020
- Author(s)
  津本浩平
- Organizer
  BioJapan 2020
- Invited
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] HDX-MSを活用したP-カドヘリンのホモ複合体に対する低分子阻害剤開発2020
- Author(s)
  妹尾暁暢、長門石曉、伊藤翔、上野剛、津本浩平
- Organizer
  第16回　日本臨床プロテオゲノミクス研究会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 膜蛋白質の膜外領域を認識する抗体の取得2020
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成VHHにおける分子挙動の解析2020
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] Thermodynamic, kinetic and computational analyses of the recognition mechanism of an antibody to a flexible protein antigen2019
- Author(s)
  金田生穂、長門石曉、黒田大祐、中木戸誠、カアベイロホセ、津本　浩平
- Organizer
  CBI学会2019年大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Recent analytical approach for evaluating protein formulation in biopharmaceuticals2019
- Author(s)
  Kouhei Tsumoto
- Organizer
  PITTCON2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質相互作用の熱測定と創薬2019
- Author(s)
  長門石曉、津本浩平
- Organizer
  第57回生物物理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 次世代抗体医薬への工学的アプローチ2019
- Author(s)
  津本浩平
- Organizer
  第32回バイオメディカル分析科学シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ホモ二量体形成蛋白質P-カドヘリンによる細胞接着阻害を可能にする新規低分子リガンド結合部位の同定2019
- Author(s)
  妹尾暁暢、長門石曉、吉田浩平、伊藤翔、上野剛、田島卓実、工藤翔太、津本浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Thermodynamic, kinetic and computational analyses of the recognition mechanism of an antibody to a flexible protein antigen2019
- Author(s)
  、金田生穂、長門石曉、黒田大祐、中木戸誠、カアベイロホセ、津本浩平
- Organizer
  情報計算化学生物学会2019年大会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 足場蛋白質Adhironに移植したαへリックスの構造解析2019
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] DESIGN AND BIOPHYSICAL EVALUATION OF Β-HAIRPIN PEPTIDES DERIVED FROM SINGLE-DOMAIN VHH ANTIBODIES2019
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] S100A4-MetAP2間相互作用に対するHelix-turn-helix構造を形成するペプチド阻害剤の解析2019
- Author(s)
  片桐直宏、長門石曉、遠藤英也、津本浩平
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Molecular dissection of antigen recognition by methylated lysine specific antibodies2019
- Author(s)
  Nakakido M, Ishii M, Kuroda D,Jose M.M. Caaveiro, Okumura S, Maruyama T, Kevin Entzminger,Tsumoto K
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] がん転移に関するLI-cadherin一塩基多型の分子メカニズム2019
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 物理化学測定と分子シミュレーションを用いた抗体親和性成熟過程の解析2019
- Author(s)
  樋渡隼人、黒田大祐、中木戸誠、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 次世代抗体工学と臨床プロテオゲノミクス研究2019
- Author(s)
  津本浩平
- Organizer
  臨床プロテオジェノミクス学会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 7.Molecular dissection of antigen recognition by methylated lysine specific antibodies2019
- Author(s)
  中木戸　誠、石井　美咲、黒田　大祐、Caaveiro MM Jose、奥村　繁、丸山　俊明、Entzminger Kevin、津本　浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 化膿レンサ球菌の鉄獲得蛋白質MtsAの特性評価及び抗体阻害剤の探索2019
- Author(s)
  竹内美結、中木戸誠、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ヒト化VHH人工合成ライブラリー構築を目指した合成ヒト化VHHの物性機能解析2019
- Author(s)
  木下清晶、森千夏、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] PRDM14の特異的制御を指向したPRDM14-EED間相互作用の物理化学解析2019
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Development and analysis of bispecific antibody for hROBO12019
- Author(s)
  Yuji Watanabe, Makoto Nakakido, Satoru Nagatoishi, Takao Hamakubo, Kouhei Tsumoto
- Organizer
  Antibody Engineering & Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成単ドメイン抗体の構造的変化の解析2019
- Author(s)
  木下清晶、森千夏、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第57回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] コンピューター技術を用いた抗体立体構造予測と分子設計2019
- Author(s)
  黒田大祐、津本浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] The efffects of protonation pf a phosphorylated amino acid on the molecular recongnation:Comparative studies of generic proteins and an antibody2019
- Author(s)
  R. Kawade, D. Kuroda, J. M. M. Caaveiro, CJ Okumura, T. Maruyama, K. Entzminger, K. Tsumoto
- Organizer
  33rd The Protein Society Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体CDR3を利用したβ-hairpin型ペプチド設計法の検討2019
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Structural insight into inhibition of homophilic dimerization mediated by cell adhesion protein P-cadherin utilizing a small molecule ligand2019
- Author(s)
  妹尾暁暢、長門石曉、吉田浩平、伊藤翔、上野剛、田島卓実、工藤翔太、津本浩平
- Organizer
  第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] コンピューター技術を用いた抗体立体構造予測と分子設計2019
- Author(s)
  黒田大祐、津本浩平
- Organizer
  第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 次世代抗体医薬品開発：加速する現状2019
- Author(s)
  津本浩平
- Organizer
  ラマンフェスタ
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 物理化学測定と分子シミュレーションを用いた抗体親和性成熟過程の解析2019
- Author(s)
  樋渡隼人、黒田大祐、中木戸誠、津本浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 病原性微生物における鉄獲得関連蛋白質の特性評価および抗体阻害剤の探索2019
- Author(s)
  中木戸誠、竹内美結、津本浩平
- Organizer
  第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Characterization of ligand-specificity of red pigment concentrating hormone receptpr of the kuruma prawn Marsupenaeus japonicus2019
- Author(s)
  田部亜季、中木戸誠、山本菜央佳、中野和民、内丸薫、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 足場蛋白質Adhiron に移植したαへリックスの構造解析2019
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 腫瘍細胞に高発現するPRDM14の機能解析と制御剤探索2019
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Disruption of Homophilic Protein-protein Interaction of P-cadherin by A Fragment Compound as A Trigger To Inhibit Cell Adhesion2019
- Author(s)
  A. Senoo, S.Nagatoishi, K. Yoshida, S. Ito, G. Ueno, T. Tashima, S. Kudo, K. Tsumoto
- Organizer
  33rd The Protein Society Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 物理化学的手法を駆使した細胞接着蛋白質P-カドヘリンのホモ二量体化相互作用を阻害する低分子の同定とその阻害機構解明2019
- Author(s)
  妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 熱力学・速度論に基づく抗Shh 抗体の抗原結合様式解析2019
- Author(s)
  金田生穂、長門石曉、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] Biophysics of the Protein-ligand Interactions to Regulate the Protein Function2019
- Author(s)
  S. Nagatoishi, K. Tsumoto
- Organizer
  10th RSC-CSJ Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] S100A4-MetAP2蛋白質間相互作用に対するペプチド阻害剤の相互作用解析2019
- Author(s)
  片桐直宏、長門石曉、遠藤英也、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 新規抗がん治療を指向したPRELP-TGFβ1相互作用の物理化学的解析2019
- Author(s)
  小菅啓史、中木戸誠、長門石曉、大沼信一、津本浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ヒト化VHH 人工合成ライブラリー構築を目指した合成ヒト化VHH の物性機能解析2019
- Author(s)
  、木下清晶、森千夏、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19 回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 分析科学が先導する次世代バイオ医薬品研究開発2019
- Author(s)
  津本浩平
- Organizer
  JASIS2019
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 腫瘍細胞に高発現するPRDM14の物理化学解析と制御剤探索2019
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第10回スクリーニング学研究会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 次世代抗体医薬品開発：現状と今後2019
- Author(s)
  津本浩平
- Organizer
  第12回複合糖質・糖鎖部会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 熱力学・速度論に基づく抗Shh抗体の抗原結合様式解析2019
- Author(s)
  金田生穂、長門石曉、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 小分子リガンドによる細胞接着蛋白質P-カドヘリンの分子間相互作用制御と構造情報に基づくリガンド設計2019
- Author(s)
  妹尾暁暢、齋藤雄太朗、伊藤翔、長門石曉、上野剛、吉田浩平、田島卓実、工藤翔太、山東信介、津本浩平
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2019
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] How We Can Improve the Affinity of An Antibody2019
- Author(s)
  津本浩平
- Organizer
  国際生物無機化学会議
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Local hydrophobic exposure of proteins regulated by hydration changes and its adsorption on a COP plastic surface2019
- Author(s)
  長門石曉、津本浩平
- Organizer
  第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] シングルドメイン抗体を用いたインターロイキンのシグナル制御2018
- Author(s)
  森千夏, 中木戸誠, 長門石曉, 津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 菌種特異性な増殖阻害剤の開発2018
- Author(s)
  中木戸誠、相川知宏、中川一路、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K19552
[Presentation] 分子シミュレーションと物理化学的解析による安定化抗体の設計2018
- Author(s)
  河上恵理、黒田大祐、中木戸誠、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] A群レンサ球菌の増殖を抑制する新規薬剤の探索と評価2018
- Author(s)
  相川知宏、星野将人、中木戸誠、長門石暁、津本浩平、中川一路
- Organizer
  第71回日本細菌学会関西支部総会
- Data Source
  KAKENHI-PROJECT-17K19552
[Presentation] 合理的な抗体設計を目指した蛋白質相互作用に関する物理化学解析2018
- Author(s)
  長門石曉、津本浩平
- Organizer
  バイオ医薬品セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] ドラッグデリバリーの標的特異性創出を目的とした部位特異的化学修飾可能な抗 OX40単鎖抗体の取得と機能解析2018
- Author(s)
  田部亜季、中野和民、中木戸誠、長門石曉、田中勇悦、津本浩平、内丸薫、渡邉俊樹
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Nanodisc-GPCRを用いた物理化学的アプローチによる低分子薬剤探索2018
- Author(s)
  吉田浩平、長門石曉、黒田大祐、津本浩平
- Organizer
  第9回スクリーニング学研究会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 病原性微生物における鉄獲得関連蛋白質の物理化学解析と新規抗菌剤の探索2018
- Author(s)
  中木戸誠、妹尾暁暢、サンドラバレンシアノ、星野将人、相川知宏、長門石曉、ホセカアベイロ、中川一路、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 化膿連鎖球菌の鉄獲得機構を阻害する新規低分子・抗体の取得2018
- Author(s)
  妹尾暁暢、星野将人、中木戸誠、長門石曉、相川知宏、中川一路、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] SPRを用いた化膿連鎖球菌の宿主感染関連PPIを阻害する天然物化合物の探索2018
- Author(s)
  妹尾暁暢、長門石曉、中木戸誠、星野将人、中山登、坂東泰彦、石崎仁將、澤竜一、五十嵐雅之、津本浩平
- Organizer
  第9回スクリーニング学研究会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Raman Spectroscopy for Biopharmaceutics: Evaluation of Conformational Stability2018
- Author(s)
  Satoru Nagatoishi, Kouhei Tsumoto
- Organizer
  RamanFest 2018 (6th International Conference on Advanced Applied Raman Spectroscopy)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] メチル化リジン特異的抗体のメチル基認識機構の解析2018
- Author(s)
  石井美咲, 中木戸誠, 奥村繁, 丸山俊昭, Kevin Entzminger, 津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 蛋白質相互作用解析と次世代創薬への期待2018
- Author(s)
  津本浩平
- Organizer
  生物工学会バイオ計測研究会　第1回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018
- Author(s)
  山﨑太一、長門石曉、中木戸誠、ホセカアベイロ、三室仁美、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 2.分子シミュレーションと物理化学的解析による安定化抗体の設計2018
- Author(s)
  河上恵理, 黒田大祐, 中木戸誠, 津本浩平
- Organizer
  18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] Physicochemical and Computational Analysis for S100A4-MetAP2 peptide Interaction2018
- Author(s)
  Naohiro Katagiri, Satoru Nagatoishi, Hideya Endo, Kouhei Tsumoto
- Organizer
  Asian Biophysics Association Symposium in conjunction with the Australian Society for Biophysics Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] メチル化リジン特異的抗体のメチル基認識機構の解析2018
- Author(s)
  石井美咲、木戸誠、奥村繁、丸山俊昭、Kevin Entzminger、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 凝集性予測シミュレーションに基づくVHH抗体の物性改善2018
- Author(s)
  山本晃一, 森千夏, 黒田大祐, 中木戸誠, 長門石曉, 津本浩平
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 物理化学測定を用いた異なる脂質環境におけるセロトニン受容体の機能評価2018
- Author(s)
  吉田浩平、長門石曉、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] LI-cadherinのTrp残基への変異導入がホモ二量体形成に与える影響2018
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質相互作用の物理化学的解析と次世代創薬2018
- Author(s)
  津本浩平、長門石曉
- Organizer
  第56回生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Role of linker region in heme transporter IsdH from Staphylococcus aureus2018
- Author(s)
  バレンシアノサンドラ、シュスコタチアナ、中木戸誠、カアベイロホセ、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018
- Author(s)
  長門石曉、津本浩平
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018
- Author(s)
  長門石曉、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] SPRを活用した鉄獲得機構を標的とした化膿連鎖球菌に対する新規抗菌剤の探索2018
- Author(s)
  妹尾暁暢、長門石曉、福田哲也、小尾奈緒子、中山登、坂東泰彦、石崎仁將、澤竜一、五十嵐雅之、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] シングルドメイン抗体を用いたインターロイキンのシグナル制御2018
- Author(s)
  森千夏、中木戸誠、長門石曉、津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 金属プロテアーゼShhに対する抗体5E1の熱力学・速度論解析2018
- Author(s)
  金田生穂、長門石曉、中木戸誠、津本浩平
- Organizer
  第46回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] FcγR相互作用解析から広がる次世代医薬品開発2018
- Author(s)
  津本浩平
- Organizer
  第10回 GFRGプロジェクトシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 1.リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018
- Author(s)
  山﨑太一、長門石曉、中木戸誠、ホセカアベイロ、三室仁美、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17H06109
[Presentation] 化膿連鎖球菌に対する抗菌剤開発を指向したヘム受容体-Hemoglobin間相互作用制御剤の探索2018
- Author(s)
  妹尾暁暢、長門石曉、中山登、坂東泰彦、石崎仁將、澤竜一、五十嵐雅之、津本浩平
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] FcRカラムを用いた異なる細胞種由来IgGの糖鎖解析2018
- Author(s)
  小菅啓史、長門石曉, 中木戸誠, 黒田大祐, 木吉真人, 石井明子, 寺尾陽介, 朝岡義晴, 大江正剛, 井出輝彦, 津本浩平
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 微生物研究が拓く生命金属科学2018
- Author(s)
  津本浩平
- Organizer
  東京大学微生物科学イノベーション連携研究機構　発足記念シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 分子シミュレーションと物理化学解析による抗体の熱安定性に関する研究2018
- Author(s)
  河上恵理、黒田大祐、中木戸誠、津本浩平
- Organizer
  日本化学会第98春季年会2018
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 肝がん細胞に発現するROBO1抗原に対する二重特異性抗体の開発2018
- Author(s)
  渡邉裕治、中木戸誠、長門石曉、浜窪隆雄、津本浩平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗体の阻害機構解明や親和性向上設計のための熱測定2018
- Author(s)
  長門石曉、津本浩平
- Organizer
  第18回日本蛋白質学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Nanodiscを用いたリン脂質二重膜環境中におけるヒトセロトニン受容体の機能解析2018
- Author(s)
  吉田浩平、黒田大祐、長門石曉、津本浩平
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Structural, physicochemical and computational analysis to reveal the mechanism of recognition of phosphorylated antigen by an antibody2018
- Author(s)
  KAWADE, Raiji、AKIBA, Hiroki; NAKAKIDO, Makoto; KURODA, Daisuke; MARUYAMA, Toshiaki; OKUMURA, Shigeru; ENTZMINGER, Kevin; CAAVEIRO, Jose; TSUMOTO, Kouhei
- Organizer
  日本化学会第98春季年会2018
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質-リガンド, 抗原-抗体相互作用解析における熱分析の活用2018
- Author(s)
  長門石曉、津本浩平
- Organizer
  熱測定スプリングスクール2019
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] SAXS及びITCによるホモ二量体形成蛋白質LI-cadherinの物性解析2018
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Regulation of collagen fibril formation and stabilization by leucine rich repeat protein, OMD2018
- Author(s)
  中木戸誠、田島卓実、長門石曉、大沼信一、津本浩平
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018
- Author(s)
  大西亮輔、長門石曉、谷口博昭、津本浩平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗体によるリン酸基認識機構の結晶構造と熱力学的手法による解析2017
- Author(s)
  河出来時、秋葉宏樹、奥村繁、丸山俊昭、K. Entzminger、津本浩平
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学日吉キャンパス(横浜市)
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] ヒストンの血管内皮細胞障害を阻害するPTX3の凝集パターン解析2017
- Author(s)
  早田敬太、中木戸誠、太期健二、高松佑一郎、山下雄史、岩成宏子、津本浩平、浜窪隆雄
- Organizer
  2017年度生命科学系会合同年次大会
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 結晶構造と変異導入解析によるウサギ抗体のリン酸基認識機構の解明2017
- Author(s)
  河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger 、津本浩平
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗原ペプチドの硫酸化がペプチドー抗体間相互作用に与える影響の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  第33回DDS学会学術大会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Thermodynamic analysis of the recognition of a flexible peptide by an antibody2017
- Author(s)
  Kouichi Miyanabe, Hiroki Akiba, Jose M. Caaveiro, Disuke Kuroda, Kouhei Tsumoto
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗体によるリン酸基認識機構の結晶構造と熱力学的手法による解析2017
- Author(s)
  河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger , 津本浩平
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Recent　progress the analytical solutions for bio-pharmacentics2017
- Author(s)
  津本浩平
- Organizer
  APPA2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Development of SpyTag-based bispecific antibodies as two-step targeting agents2017
- Author(s)
  Hiroki Akiba ,Kyohei Yumura, Kensuke Takayanagi, Takao Hamakubo, Kouhei Tsumoto
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質相互作用の熱力学解析と創薬2017
- Author(s)
  津本浩平, 長門石曉
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic effects of intramolcular hydrogen bonds within peptide on the peptide-antibody interaction2017
- Author(s)
  Kazuhiro Miyanabe, Hiroki Akiba, Jose Caaveiro, Makoto Nakakido, Daisuke Kuroda, Kouhei Tsumoto
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Specificity-determining structural elements of antibody against antigen2017
- Author(s)
  Hiroki Akiba, Ryosuke Yoshida, Raiji Kawade, Jose M. Caaveiro, Kouhei Tsumoto
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質相互作用の物理化学解析に基づくリガンドスクリーニング2017
- Author(s)
  津本浩平, 長門石曉
- Organizer
  日本化学会第98春季年会2018
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] hermodynamic elucidation of binding process for protein-ligand interactions to propose a drug design2017
- Author(s)
  Satoru Nagatoishi, Kouhei Tsumoto
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] ホモ2量体形成蛋白質P-cadherinを標的とした蛋白質間相互作用阻害剤の探索2017
- Author(s)
  妹尾暁暢、田島卓実、工藤翔太、長門石曉、津本浩平
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017
- Author(s)
  内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] LI-cadherinのホモダイマー形成の細胞アッセイ及び物理化学的手法による分析2017
- Author(s)
  由井杏奈、菊池智佳、工藤翔太、秋葉宏樹、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  日本化学会第97春季年会(2017)
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗原ペプチドの硫酸化がペプチド－抗体間相互作用に与える影響の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 物理化学的アプローチによる蛋白質間相互作用阻害剤の探索2017
- Author(s)
  長門石曉, 津本浩平
- Organizer
  第65回質量分析総合討論会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] シクロオレフィンポリマーCOP表面に対するホフマイスター効果に依存したタンパク質吸着制御2017
- Author(s)
  長門石曉、藤田梨紗子、足達慧、西岡寛哉、二宮英隆、彼谷高敏、高井まどか、津本浩平
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Recent Analytical Solutions for Bio-pharmaceutical Practice2017
- Author(s)
  津本浩平
- Organizer
  PITCON 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 結晶構造と変異導入解析によるウサギ抗体のリン酸基認識機構の解明2017
- Author(s)
  河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger、津本浩平
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 分析技術が拓く次世代バイオ医薬品開発研究2017
- Author(s)
  津本浩平
- Organizer
  一般社団法人日本分析機器工業会, 日本科学機器協会 / JASIS 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 低分子創薬の技術開発における物理化学バリデーション2017
- Author(s)
  長門石曉、津本浩平
- Organizer
  第30回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 天然変性蛋白質Mint3とFIH-1の相互作用解析におけるH/D交換質量分析法の適用2017
- Author(s)
  展天承、中山佳昭、長門石曉、坂本毅治、清木元治、津本浩平
- Organizer
  第65回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗原配列の硫酸化が抗体との相互作用に与える影響の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉宏樹、カアベイロホセ、黒田大祐、中木戸誠、高松佑一郎、山下雄史、津本浩平
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 蛋白質相互作用解析が拓く革新的次世代創薬2017
- Author(s)
  津本浩平
- Organizer
  第15回RCGMフロンティアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic analysis of the effect of sulfation on a peptide-antibody interaction2017
- Author(s)
  宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 次世代の低分子創薬を拓く蛋白質-低分子間相互作用の物理化学的解析2017
- Author(s)
  長門石曉、カアベイロホセ、津本浩平
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 熱分析から低分子薬剤の探索・設計に挑む2017
- Author(s)
  長門石曉, Caaveiro Jose,　津本浩平
- Organizer
  第30回九州分析化学若手の会春の講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Lipids as structural elements in pore formation2016
- Author(s)
  Koldo Morante, Kouji Tanaka, Jose M. Caaveiro, Kouhei Tsumoto
- Organizer
  IMI translocation 2016 - Novel approaches to fight bacteria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016
- Author(s)
  Tomoya Takahashi, Sartoru Nagatoishi, Daisuke Kuroda, Kouhei Tsumoto
- Organizer
  CALCON2016
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Biophysical approach to find the inhibitors of CapF and ERK2 enzyme in FBDD2016
- Author(s)
  Satoru Nagatoishi, Kouhei Tsumoto
- Organizer
  JCUP VII
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 抗金属錯体抗体と多種の金属錯体との相互作用における親和性創出基盤2016
- Author(s)
  秋葉宏樹、吉田良介、カアベイロホセ、津本浩平
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] コラーゲン線維形成プロセスを制御する蛋白質Osteomodulinの制御機構解析2016
- Author(s)
  田島卓実、長門石暁、カアベイロホセ、中木戸誠、相良洋、大沼信一、津本浩平
- Organizer
  第10回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 次世代抗体開発を指向したin silicoとin vitroをつなぐ熱力学解析2016
- Author(s)
  長門石曉、津本浩平
- Organizer
  バイオプロセス講演会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 疾患治療を目的とした抗PRELP抗体の結合特性の解明2016
- Author(s)
  野中桃子、田島卓実、長門石曉、岩成宏子、浜窪隆雄、大沼信一、津本浩平
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ(静岡市)
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 次世代薬剤設計を指向した蛋白質－低分子間相互作用のプロセス熱力学2016
- Author(s)
  長門石曉、山口奏、津本浩平
- Organizer
  第10回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] リン酸化ペプチドを抗原とするウサギIgGとscFvについての熱力学的手法を用いた物理化学解析2016
- Author(s)
  河出来時、秋葉宏樹、奥村繁、丸山俊昭、K. Entzminger、津本浩平
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] SPR and ITC-based small-molecule screening to find inhibitors of protein-protein interaction2016
- Author(s)
  Satoru Nagatoishi, Kouhei Tsumoto
- Organizer
  DiPIA 2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Basis of cell-membrane damage by a protein nanopore2016
- Author(s)
  Jose M.M. Caaveiro、Koji Tanaka、Koldo Morante、Kouhei Tsumoto
- Organizer
  Todai-Tsinghua Joint Workshop for Frontiers in Bioengineering and Biomedical Engineering
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-03-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] ドラッグデリバリーを指向した二重特異性抗体の抗原上形成2016
- Author(s)
  秋葉宏樹、高柳憲介、湯村恭平、浜窪隆雄、津本浩平
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  石川県立音楽堂、もてなしドーム地下イベント広場(金沢市)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] How we can improve affinity of antibodies for the targets towards therapeutics2016
- Author(s)
  Kouhei Tsumoto
- Organizer
  CALCON2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Thermodynamics of the interaction between proteins and small compounds in drug discovery2016
- Author(s)
  長門石曉、津本浩平
- Organizer
  分子研研究会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 9F NMR and SPR Screening for the Development of an Inhibitor of the Tob1-CNOT7 Interaction2016
- Author(s)
  Kouhei Soeda ,Satoru Nagatoishi, E. Kato, M. Yamamoto, Kouhei Tsumoto
- Organizer
  The 27th International Conference on Magnetic Resonance in Biological Systems
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 熱力学的解析を基盤とした茶カテキン-蛋白質間の分子認識機構の解明2016
- Author(s)
  高橋知也、長門石曉、黒田大祐、津本浩平
- Organizer
  第21回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] 合理的設計指針構築を目指したVHH抗原相互作用機構解析2016
- Author(s)
  田村浩子、木吉真人、秋葉宏樹、カアベイロホセ、津本浩平
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ(静岡市)
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 抗ペプチド抗体による抗原ペプチド構造の認識機構の解明2016
- Author(s)
  宮鍋一紘、秋葉宏樹、カアベイロホセ、黒田大祐、中木戸誠、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016
- Author(s)
  Sartoru Nagatoishi, Y. Tanabe, Kouhei Tsumoto
- Organizer
  CALCON2016
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02420
[Presentation] Lipid-protein partnering during pore-formation of fragaceatoxinC2016
- Author(s)
  Koldo Morante、Jose M.M. Caaveiro、Koji Tanaka、Kouhei Tsumoto
- Organizer
  The Biophysical Society 60th Annual Meeting
- Place of Presentation
  Los Angeles（U.S.A.）
- Year and Date
  2016-02-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Cell adhesion of human P-cadherin regulated by a Self-Chaperone mechanism2015
- Author(s)
  Shota Kudo、Jose M.M. Caaveiro、Kouhei Tsumoto
- Organizer
  9th Retreat Meeting of the IMSUT
- Place of Presentation
  東京大学検見川セミナーハウス（千葉県千葉市花見川区）
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 抗DOTA金属錯体抗体の一本鎖化とその分子認識メカニズムの解明2015
- Author(s)
  秋葉宏樹、吉田良介、カアベイロホセ、津本浩平
- Organizer
  日本分子イメージング学会第１０回学術集会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Intravital imaging of drug delivery systems2015
- Author(s)
  Y. Matsumoto
- Organizer
  2015 Conference on developmental Biology Scientific & Drug Delivery System Program
- Place of Presentation
  Academia Sinica (Taipei, Taiwan)
- Year and Date
  2015-11-10
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 自己組織化を利用したDDSのための改変抗体の作製2015
- Author(s)
  高柳憲介, 湯村恭平, 秋葉宏樹, 松長遼, 浜窪隆雄, 津本浩平
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-03
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 膜孔形成毒素の自己組織化に生体膜の組成とダイナミクスが与える影響の分子基盤2015
- Author(s)
  津本浩平 (代理:田中耕路)、カアベイロホセ
- Organizer
  第５３回日本生物物理学会年会
- Place of Presentation
  金沢大学角間キャンパス（石川県金沢市）
- Year and Date
  2015-09-14
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] The protein-protein interactions in highly concentrated antibody solution investigated by Raman spectroscopy．2015
- Author(s)
  太田周志、長門石曉、野口慎太郎、津本浩平
- Organizer
  第５３回日本生物物理学会年会
- Place of Presentation
  金沢大学角間キャンパス（石川県金沢市）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 抗リゾチームシングルドメイン抗体の抗原認識における熱力学的特性2015
- Author(s)
  秋葉宏樹、田村浩子、木吉真人、カアベイロホセ、津本浩平
- Organizer
  第９回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学（熊本県熊本市）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 金属イオンデリバリーのための抗金属錯体一本鎖抗体の開発とその性質解析2015
- Author(s)
  秋葉宏樹、吉田良介、カアベイロホセ、津本浩平
- Organizer
  第３１回日本ＤＤＳ学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Biophysical cross-validation in fragment screening of fluorinated chemical library toward FBDD using SPR, ITC and 19F NMR2015
- Author(s)
  Satoru Nagatoishi、Sou Yamaguchi、Keita Kajita、Etsuko Katoh、Hiroyuki Akiyama、Satoru Kanai、Toshio Furuya、Kouhei Tsumoto
- Organizer
  The 43rd Symposium on Structural Activity Relationship 2015 The 10th Japan-China Joint Symposium on Drug Discovery and Development
- Place of Presentation
  新潟日報メディアシップ日報ホール（新潟県新潟市）
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Mechanism of self-assembly of a transmembrane pore triggered by specific biomembranes2015
- Author(s)
  Koji Tanaka、Jose Caaveiro、Koldo Morante、Kouhei Tsumoto
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
- Place of Presentation
  Honolulu, Hawaii（U.S.A.）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] ドラッグデリバリーを指向した抗ペプチド抗体作製および抗原ペプチド融合蛋白質との相互作用解析2015
- Author(s)
  宮鍋一紘, 秋葉宏樹, カアベイロホセ, 中木戸誠, 岩成宏子, 新井修, 浜窪隆雄, 津本浩平
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-02
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of enzyme-loaded polyion complex vesicles for in vivo nanoreactor2015
- Author(s)
  Y. Anraku, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, A. Kishimura, M. Kano, Y. Urano, N. Nishiyama, K. Kataoka
- Organizer
  THE INTERNATIONAL CHEMICAL CONGRESS OF PACIFIC BASIN SOCIETIES (PACIFICHEM2015)
- Place of Presentation
  Hawaii Convention Center (Hawaii, USA)
- Year and Date
  2015-12-15
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 抗EDTA抗体CHA255scFvの抗原認識機構解析2015
- Author(s)
  吉田良介, 秋葉宏樹, 津本浩平
- Organizer
  第95回日本化学会年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Structural and mechanistic basis of capsular polysaccharide-synthesizing enzymes CapE/CapF, and the route to discovery novel inhibitors with antibacterial properties2015
- Author(s)
  Jose M.M. Caaveiro、Takamistsu Miyafusa、Takeru Chigira、Koichiro Nakano、Satoru Nagatoishi、Kouhei Tsumoto
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
- Place of Presentation
  Honolulu, Hawaii（U.S.A.）
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 溶液中の動態から示される難溶性蛋白質KAP8.1の構造と機能2014
- Author(s)
  ガンバットジャホラン、松長遼、秋葉宏樹、下村裕、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 抗DOTA単鎖抗体の抗原認識における金属イオンの効果2014
- Author(s)
  秋葉宏樹、吉田良介、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2014-03-27
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] プロテオグリカンOsteomodulinの物理化学的解析2014
- Author(s)
  田島卓実、中木戸誠、長門石曉、大沼信一、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 抗原ペプチドへの蛋白質融合が抗原－抗体相互作用に及ぼす影響の熱力学的評価2014
- Author(s)
  宮鍋一紘、秋葉宏樹、中木戸誠、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 抗原ペプチドへの蛋白質融合が抗原-抗体相互作用に及ぼす影響の熱力学的評価2014
- Author(s)
  宮鍋一紘、秋葉宏樹、中木戸誠、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-10-16
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Structural analysis of the pore-forming tosin FraC with multiple lipids bound2014
- Author(s)
  K. Tanaka, Jose M. M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas, K. Tsumoto
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  Moscone Center (San Francisco, California, USA
- Year and Date
  2014-02-18
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] プレターゲティング法を目指した低免疫原性化コアストレプトアビジン融合抗体の開発2014
- Author(s)
  秋葉宏樹, 湯村恭平, 宇井美穂子, 土居洋文, 杉山暁, 浜窪隆雄, 児玉龍彦, 津本浩平
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学(東京都港区)
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 抗DOTA一本鎖抗体のDOTA認識機構の熱力学と構造による解明2014
- Author(s)
  吉田良介, 秋葉宏樹, 津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] プレターゲティング法を目指した低免疫原性化コアストレプトアビジン融合抗体の開発2014
- Author(s)
  秋葉宏樹、湯村恭平、宇井美穂子、土居洋文、杉山暁、浜窪隆雄、児玉龍彦、津本浩平
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶応義塾大学薬学部芝共立キャンパス
- Year and Date
  2014-07-30
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 高機能性抗体の設計に向けた抗P-cadherin抗体の物性、構造解析2014
- Author(s)
  工藤翔太、Caaveiro Jose、長門石曉、浜窪隆雄、児玉龍彦、松浦正、須藤幸夫、津本浩平
- Organizer
  第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根高原ホテル
- Year and Date
  2014-07-14
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 多機能性タンパク質PHB2の物性解析2014
- Author(s)
  千吉良岳、長門石曉、片桐豊雅、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 生命分子相互作用解析 : ITCとSPR2014
- Author(s)
  長門石曉、津本浩平
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学(熊本)
- Year and Date
  2014-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 抗DOTA一本鎖抗体のDOTA認識機構の熱力学と構造による解明2014
- Author(s)
  吉田良介、秋葉宏樹、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-10-17
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 難溶性蛋白質KAP8.1の溶液状態と粉末状態の多面的な解析による特徴付け2014
- Author(s)
  Ganbat Javkhlan、松長遼、秋葉宏樹、下村裕、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] STRUCTURAL ANALYSIS OF THE PORE-FORMING TOXIN FRAC WITH MULTIPLE LIPIDS BOUND.2014
- Author(s)
  Koji Tanaka, Jose M. M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas, Kouhie Tsumoto
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  Moscone Center (アメリカ合衆国/カリフォルニア州)
- Year and Date
  2014-02-15
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 荷電性アミノ酸の導入による高親和性抗体の合理的分子設計2014
- Author(s)
  木吉真人、Caaveiro Jose、三浦恵梨、長門石曉、中木戸誠、曽我真司、白井宏樹、川畑茂樹、中村春木、津本浩平
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶応義塾大学薬学部芝共立キャンパス
- Year and Date
  2014-07-31
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Tethering PEG density on polyplex micelles and stealthiness in blood circulation2013
- Author(s)
  K. Osada, T. A. Tockary, Q. Chen, A. Dirisala, K. Machitani, T. Nomoto, Y. Matsumoto, K. Kataoka
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii, USA)
- Year and Date
  2013-07-21
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013
- Author(s)
  長門石曉、津本浩平
- Organizer
  第17回コロイド・界面フォーラム
- Place of Presentation
  KKR江の島ニュー向洋(神奈川県藤沢市)
- Year and Date
  2013-07-18
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Analysis of hypo-immunogenic core streptavidin and construction of fusion-an2013
- Author(s)
  湯村恭平, 宇井美穂子、土居洋文、杉山暁、浜窪隆雄、児玉龍彦、津本浩平
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] フラグメントライブラリーによる莢膜合成酵素CapFの阻害剤探索2013
- Author(s)
  中納広一郎、宮房孝光、長門石曉、Jose Caaveiro、津本浩平
- Organizer
  第４回スクリーニング学研究会
- Place of Presentation
  東京大学伊藤謝恩ホール(東京都文京区)
- Year and Date
  2013-11-29
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 希土類錯体によるペプチド・蛋白質のチロシンリン酸化検出法の構築2013
- Author(s)
  秋葉宏樹、須磨岡淳、浜窪隆雄、津本浩平、小宮山眞
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 親和性向上を目指した抗インターフェロンγレセプター抗体の合理的改変2013
- Author(s)
  木吉真人, 三浦恵理、長門石曉、Jose M. M. Caaveiro M. M、中木戸誠、曽我真司、白井宏樹、河畑茂樹、中村春木、津本浩平
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Protein shackle : A polymerizing scaffold for functional protein2013
- Author(s)
  R. Matsunaga, S. Nagatoishi, K. Tsumoto
- Organizer
  5th Annual PEGS Europe
- Place of Presentation
  Sheraton Lisboa Hotel & Spa (Lisbon, Portugal)
- Year and Date
  2013-11-04
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Actinoporin, FraCは二つの異なる基質-脂質と糖鎖を一つのポケットで認識する2013
- Author(s)
  田中耕路、Jose M. M. Caaveiro, 津本浩平
- Organizer
  第60回トキシンシンポジウム
- Place of Presentation
  楓香荘(兵庫県宍粟市)
- Year and Date
  2013-07-17
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] DDS evaluation using intravital real-time laser scanning confocal microscopy2013
- Author(s)
  Y. Matsumoto, T. Nomoto, K. Toh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii, USA)
- Year and Date
  2013-07-21
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013
- Author(s)
  長門石曉、津本浩平
- Organizer
  第17回コロイド・界面フォーラム
- Place of Presentation
  KKR江の島ニュー向洋(神奈川県藤沢市）
- Year and Date
  2013-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 低免疫原性化コアストレプトアビジンを用いた融合抗体の構築と解析2013
- Author(s)
  湯村恭平,宇井美穂子,土居洋文,杉山暁,浜窪隆雄,児玉龍彦,津本浩平
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] FraCの生体膜上での自己組織化は脂質ドメインの形成により促進される2013
- Author(s)
  田中耕路, Koldo Morante, Jose M. M. Caaveiro, J. M. Gonzalez-Manas, 津本浩平
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 病原性細菌のHeme輸送システムを阻害する低分子化合物の探索2013
- Author(s)
  長門石曉、下村拓矢、安部良太、星野将人、Jose Caaveiro、津本浩平
- Organizer
  第４回スクリーニング学研究会
- Place of Presentation
  東京大学伊藤謝恩ホール(東京都文京区)
- Year and Date
  2013-11-29
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 細胞接着蛋白質P-cadherinの同種親和的二量体形成機構の解明2013
- Author(s)
  工藤翔太,ホセカアベイロ,長門石暁,浜窪隆雄,児玉龍彦,松浦正,須藤幸夫,津本浩平
- Organizer
  第86回日本生化学学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 天然変性型蛋白質の機能制御へ向けた核酸結合蛋白質YB-1の物理化学的解析2013
- Author(s)
  長門石曉、田邊裕美子、西方敬人、杉本直己、津本浩平
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋大学(愛知県名古屋市)
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] 熱力学的相互作用解析と分子動力学シミュレーションによる抗体の親和性向上のメカニズムの研究2013
- Author(s)
  渡部貴大,長門石曉,山下雄史,中山泰亮,溝端栄一,浜窪隆雄,井上豪,津本浩平,児玉龍彦,藤谷秀章
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 細胞接着蛋白質P-cadherinの同種親和的二量体形成機構の解明2013
- Author(s)
  工藤翔太、Jose M. M. Caaveiro、長門石曉、浜窪隆雄、児玉龍彦、松浦正、須藤幸夫、津本浩平
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-24000011
[Presentation] Thermodynamic Analyses of Binding and Transfer of Heme : Isd System2011
- Author(s)
  Tsumoto K, Caaveiro J. M. M., Abe R, Moriwaki Y, Vu N, Watanabe M, Tanaka Y
- Organizer
  14th Asian Chemical Congress 2011(14ACC)
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Structural and functional analysis of Capsular polysaccharide synthesizing enzyme CapF from Staphylococcus aureus2011
- Author(s)
  Miyafusa T, Tanaka Y, Caaveiro J. M. M., Kuroda M, Yao M, Ohta T, Tanaka I, Tsumoto K
- Organizer
  The IXth European Symposium of The Protein Society
- Place of Presentation
  Stockholm-Stockholm University, Aula Magna
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Targeted glycosylation of "non-core region" of Interleukin 11 modulates its biological function2011
- Author(s)
  Yanaka S, Sano E, Naruse N, Caaveiro J. M. M., Tsumoto K
- Organizer
  Immunology 2011
- Place of Presentation
  Moscone Center(San Francisco・USA)
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Structural and functional analysis of capsular polysaccharide synthesizing enzyme CapF2010
- Author(s)
  T. Miyafusa ; Y. Tanaka ; J. Martinez Caaveiro ; M. Kuroda ; M. Yao ; T. Ohta ; I. Tanaka ; K. Tsumoto
- Organizer
  2010環太平洋国際化学会
- Place of Presentation
  ハワイコンベンションセンター
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Hawaii Convention Centor Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents2010
- Author(s)
  安部良太・ホセマルチネスカアベイロ・津本浩平
- Organizer
  Pacific Chem 2010
- Place of Presentation
  米国ハワイ州
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Aromatic Interactions are Essential for Carbohydrate Recognition by an Enzyme2010
- Author(s)
  Caaveiro, J. M. M., Kobe, A., Clifton, J. G., Ringe, D., Petsko, G. A. and Tsumoto, K
- Organizer
  DiPiA2010
- Place of Presentation
  Skipper Hotel. Barcelona,スペイン
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] Three Hot-Spot Regions Define the High Affinity of Human Interleukin 15 for its Private alpha-Receptor2009
- Author(s)
  Caaveiro, J. M. M., Sakamoto, S., Sano, E., Kudou, M. and Tsumoto, K
- Organizer
  The 23rd Symposium of the Protein Society
- Place of Presentation
  Boston, Massachusetts, USA
- Data Source
  KAKENHI-PROJECT-21360398
[Presentation] 材料・医療への展開を目指した蛋白質相互作用解析2008
- Author(s)
  津本
- Organizer
  日本分析化学会東北支部会
- Place of Presentation
  東北大学
- Year and Date
  2008-03-22
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] Protein Interaction Analyses for Materials and Medicines2008
- Author(s)
  Tsumoto
- Organizer
  10th Symposium on Biomolecular Chemistry
- Place of Presentation
  Kumamoto
- Year and Date
  2008-01-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] 「蛋白質相互作用解析:材料・医療への展開」2008
- Author(s)
  津本
- Organizer
  第10回日本化学会生命化学研究会シンポジウム
- Place of Presentation
  熊本大学
- Year and Date
  2008-01-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Development of Materials and. Medicines based on Protein Interaction Analyses2008
- Author(s)
  Tsumoto
- Organizer
  Symposium on Analytical Chemistry
- Place of Presentation
  Sendai
- Year and Date
  2008-03-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] 「蛋白質相互作用解析:材料・医療への展開」2008
- Author(s)
  津本
- Organizer
  第10回日本化学会生命化学研究会シンポジウム
- Place of Presentation
  熊本大学
- Year and Date
  2008-01-11
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] 材料・医療への展開を目指した蛋白質相互作用解析2008
- Author(s)
  津本
- Organizer
  日本分析化学会東北支部会
- Place of Presentation
  東北大学
- Year and Date
  2008-03-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Role of Arginine in Handling Proteins.2007
- Author(s)
  Tsumoto
- Organizer
  第1回日本スイスケミカルバイオロジー会議
- Place of Presentation
  スイスETH(ローザンヌ)
- Year and Date
  2007-06-25
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] Chromatography using Arginine : Antibodies2007
- Author(s)
  Tsumoto
- Organizer
  Symposium on Liquid Chromatographies
- Place of Presentation
  Noda
- Year and Date
  2007-06-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Role of Arginine in Handling Proteins2007
- Author(s)
  Tsumoto
- Organizer
  第1回日本スイスケミカルバイオロジー会議
- Place of Presentation
  スイスETH(ローザンヌ)
- Year and Date
  2007-06-25
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
- Author(s)
  津本
- Organizer
  第45回目本生物物理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Role of Arginine in Handing Proteins.2007
- Author(s)
  Tsumoto
- Organizer
  第1回日本イスケミカルバイオロジー会議
- Place of Presentation
  スイスETH(ローザンヌ)
- Year and Date
  2007-06-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
- Author(s)
  津本
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] アルギニンを用いたクロマトグラフィー:抗体を中心に2007
- Author(s)
  津本
- Organizer
  第204回液体クロマトグラフィー研究懇談会
- Place of Presentation
  東京理科大学
- Year and Date
  2007-06-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Role of Arginine in Protein Handling2007
- Author(s)
  Tsumoto
- Organizer
  1st Symposium on Swiss-Japan Chemical Biology Conference
- Place of Presentation
  Swiss
- Year and Date
  2007-06-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Current status of cancer immunotherapy and its perspectives2007
- Author(s)
  Tsumoto
- Organizer
  Annual Meeting of Japan Cancer Society
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] 癌免疫療法の現状と今後2007
- Author(s)
  津本
- Organizer
  日本癌学会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
- Author(s)
  津本
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] アルギニンを用いたクロマトグラフィー:抗体を中心に2007
- Author(s)
  津本
- Organizer
  第204回液体クロマトグラフィー研究懇談会
- Place of Presentation
  東京理科大学
- Year and Date
  2007-06-29
- Data Source
  KAKENHI-PROJECT-19021011
[Presentation] Evolved Thermodynamic Analyses : Protein Interaction2007
- Author(s)
  Tsumoto
- Organizer
  Annual Meeting of Biophysics
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] 癌免疫療法の現状と今後2007
- Author(s)
  津本
- Organizer
  日本癌学会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17360393
[Presentation] Protein shackle: A polymerizing scaffold for functional protein
- Author(s)
  Ryo Matsunaga, Satoru Nagatoishi, Kouhei Tsumoto
- Organizer
  5th Annual PEGS Europe
- Place of Presentation
  Sheraton Lisboa Hotel & Spa (ポルトガル/リスボン)
- Year and Date
  2013-11-04 – 2013-11-08
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 化膿レンサ球菌由来Shr、Shpによるヘム輸送機構の物理化学的解析
- Author(s)
  星野将人、Caaveiro Jose、長門石曉、中川一路、津本浩平
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 構造情報に基づくDJ-1二量体形成へのC末端モチーフの寄与の解明
- Author(s)
  田代晋也、Jose M. M. Caaveiro、森脇由隆、Shulin Ju、Quyen Hoang、津本浩平
- Organizer
  第３６回分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-03 – 2013-12-06
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 溶液中の動態から示される難溶性蛋白質KAP8.1の構造と機能
- Author(s)
  ガンバットジャホラン、松長遼、秋葉宏樹、下村裕、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス( 愛知県名古屋市)
- Year and Date
  2014-03-27 – 2014-03-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] プロテオグリカンOsteomodulinの物理化学的解析
- Author(s)
  田島卓実、中木戸誠、長門石曉、大沼信一、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス( 愛知県名古屋市)
- Year and Date
  2014-03-27 – 2014-03-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 機能制御を目指した疾患関連蛋白質Mint3の物性解析
- Author(s)
  中山佳昭、田代晋也、長門石曉、坂本毅治、清木元治、津本浩平
- Organizer
  第14回日本蛋白質科学会
- Place of Presentation
  ワークピア横浜(神奈川県横浜市)
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 黄色ブドウ球菌由来の莢膜合成酵素CapFに結合する低分子化合物の解析
- Author(s)
  長門石曉、中納広一郎、宮房孝光、Caaveiro Jose、津本浩平
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 骨石灰化機構に関するプロテオグリカンOsteomodulinの物性解析
- Author(s)
  田島卓実、長門石曉、Caaveiro Jose、工藤翔太、中木戸誠、大沼信一、津本浩平
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 生命分子相互作用解析：ITC とSPR
- Author(s)
  長門石曉、津本浩平
- Organizer
  日本薬学会第134年会
- Place of Presentation
  くまもと県民交流会館パレアホール(熊本県熊本市)
- Year and Date
  2014-03-27 – 2014-03-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 乳癌関連蛋白質BIG3とPHB2の物性解析
- Author(s)
  千吉良岳、長門石曉、片桐豊雅、津本浩平
- Organizer
  第14回日本蛋白質科学会
- Place of Presentation
  ワークピア横浜(神奈川県横浜市)
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Staphylococcus aureus莢膜合成酵素CapFと低分子化合物の物理化学的な相互作用解析
- Author(s)
  長門石曉、中納広一郎、宮房孝光、Caaveiro　Jose、津本浩平
- Organizer
  第42回構造活性相関シンポジウム
- Place of Presentation
  くまもと森都心プラザ(熊本県熊本市)
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 黄色ブドウ球菌由来莢膜合成酵素CapF の補酵素取り込み機構に関する熱量解析
- Author(s)
  中納広一郎、宮房孝光、Jose Manuel Martinez Caaveiro、長門石曉、津本浩平
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館(鳥取県鳥取市)
- Year and Date
  2013-06-12 – 2013-06-14
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 多機能性タンパク質PHB2のフォールディング状態に対する疎水環境の影響
- Author(s)
  Takeru Chigira、Satoru Nagatoishi, Toyomasa Katagiri, Kouhei Tsumoto
- Organizer
  第52回日本生物物理学会年会（BSJ2014）
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] パーキンソン病関連蛋白質DJ-1 の金属結合特異性に関する物理化学的解析
- Author(s)
  田代晋也、Caaveiro Jose、Chun-Xiang Wu、Quyen Hoang、津本浩平
- Organizer
  第１２回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根高原ホテル(神奈川県足柄下郡)
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Biophysical Approach of Fragment Screening to inhibit the heme transfer system of Pathogenic bacteria
- Author(s)
  Satoru Nagatoishi, Takuya Shimomura, Ryota Abe, Masato Hoshino, Jose Caaveiro, Kouhei Tsumoto
- Organizer
  CBI学会2013年大会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Year and Date
  2013-10-28 – 2013-10-31
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 物理化学的手法を用いたパーキンソン病関連蛋白質DJ-1と亜鉛間の結合解析
- Author(s)
  田代晋也、カアベイロホセ、Wu Chun-Xiang、Hoang Quyen、津本浩平
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Thermodynamic tools in the early stages of Drug Discovery
- Author(s)
  Jose Caaveiro, A. Kobe, S. Tashiro, D. Kajihara, M. Kikkawa T. Mitani, K. Tsumoto
- Organizer
  4th Asia-Pacific Protein Association
- Place of Presentation
  ICC Jeju(韓国/済州島)
- Year and Date
  2014-05-17 – 2014-05-20
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Inhibitor Screening of Capsular Polysaccharide Synthesizing Enzyme CapF from Staphylococcus aureus
- Author(s)
  Koichiro Nakano, Takamitsu Miyafusa, Satoru Nagatoishi, Jose Caaveiro, Kouhei Tsumoto
- Organizer
  CBI学会2013年大会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Year and Date
  2013-10-28 – 2013-10-31
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Molecular basis of heme capture by Isd system of Staphylococcus aureus
- Author(s)
  Jose Caaveiro, N. Vu, K. Morante, Y.Moriwaki, R. Abe, K. Tsumoto
- Organizer
  The 28th annual symposium of The Protein Society
- Place of Presentation
  Manchester Grand Hyatt(アメリカ合衆国/カリフォルニア州)
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Actinoporin, FraCは二つの異なる基質－脂質と糖鎖を一つのポケットで認識する
- Author(s)
  田中耕路、Jose M. M. Caaveiro, 津本浩平
- Organizer
  第60回トキシンシンポジウム
- Place of Presentation
  楓香荘(兵庫県宍粟市)
- Year and Date
  2013-07-17 – 2013-07-19
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Thermodynamic and structural characterization of the binding of Zn(II) and other molecules to human protein DJ-1
- Author(s)
  田代晋也、Caaveiro Jose、Chun-Xiang Wu、Quyen Hoang、津本浩平
- Organizer
  The 28th annual symposium of The Protein Society
- Place of Presentation
  Manchester Grand Hyatt(アメリカ合衆国/カリフォルニア州)
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] Structural Snapshots of the α-helical Pore-forming Toxin FraC Reveal The Molecular Basis Of Its Activation In Membranes.
- Author(s)
  Koji Tanaka, Jose Caaveiro, Kouhei Tsumoto
- Organizer
  The 28th annual symposium of The Protein Society
- Place of Presentation
  Manchester Grand Hyatt(アメリカ合衆国/カリフォルニア州)
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 膜孔形成蛋白質FraCの構造変化機構の解析：可溶性構造から膜貫通構造までの変遷
- Author(s)
  Koji Tanaka、Jose Caaveiro, Kouhei Tsumoto
- Organizer
  第52回日本生物物理学会年会（BSJ2014）
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 特異的分子認識により重合する蛋白質の設計とその応用
- Author(s)
  松長遼、長門石曉、津本浩平
- Organizer
  第14回日本蛋白質科学会
- Place of Presentation
  ワークピア横浜(神奈川県横浜市)
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 多機能性タンパク質PHB2の物性解析
- Author(s)
  千吉良岳、長門石曉、片桐豊雅、津本浩平
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学東山キャンパス( 愛知県名古屋市)
- Year and Date
  2014-03-27 – 2014-03-30
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 毒素FraCが形成する蛋白質と脂質からなる膜孔構造
- Author(s)
  田中耕路、Jose M.M. Caaveiro、Koldo Morante、Juan Manuel Gonzalez-Manas、津本浩平
- Organizer
  日本結晶学会平成26年度年会
- Place of Presentation
  東京大学(東京都文京区)
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-25249115
[Presentation] 還元環境に応答して重合する蛋白質Protein shackleの開発
- Author(s)
  松長遼、長門石曉、津本浩平
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学(岡山県岡山市)
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25249115
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# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
104. 真嶋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
105. 浦野健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
106. 杉浦智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
107. 松井敏高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
108. 田部亜季

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
109. 伊藤耕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
110. 濡木理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
111. 田村康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
112. 松村浩由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
113. 秋葉宏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsumoto Kouhei 津本 浩平

TSUMOTO Kouhei 津本 浩平

Research Projects

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Elucidation and Control of Local Fractions in Protein EngineeringPrincipal Investigator

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Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemArea Organizer

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Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemPrincipal Investigator

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Development of molecular recognition elements for understanding and regulation of biometal dynamicsPrincipal Investigator

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Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approachesPrincipal Investigator

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Ligand discovery based on biophysical analysesPrincipal Investigator

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Tsumoto Kouhei 津本浩平

TSUMOTO Kouhei 津本浩平