KOBAYASHI Ryoji 小林良二

Researcher Number	00020917
Other IDs
Affiliation (based on the past Project Information) *help	2003 – 2011: Kagawa University, Medicine, Professor, 医学部, 教授 2004: Kagawa University, Signal Transduction Sciences, Professor, 医学部, 教授 1995 – 2002: Kagawa Medical School, Faculty of Medicine, Professor, 医学部, 教授 1990 – 1992: 名古屋大学, 医学部, 助教授 1986 – 1988: 秋田大学, 医学部, 助教授 1986: Department of Biochemistry,Akita University School of Medicine, 医学部, 助教授
Review Section/Research Field	Principal Investigator 物質生物化学 / Plastic surgery / Pathological medical chemistry / General pharmacology / 代謝生物化学 / Neurochemistry/Neuropharmacology Except Principal Investigator Pathological medical chemistry / Functional biochemistry / Functional biochemistry / Bacteriology (including Mycology) … More / Bacteriology (including Mycology) / Kidney internal medicine / Dermatology / Neurochemistry/Neuropharmacology / Neuroscience in general / General pharmacology Less
Keywords	Principal Investigator microfibril / extracellular matrix protein / ミクロフィブリル / 細胞接着 / エラスチン / Smith-Magenis症候群 / 細胞外マトリックス蛋白質 / 36kDa MAGP / 36kDaMAGP / RGD蛋白質 … More / inhibitor / blood vessel / EF hand protein / Smith-Magenis syndrome / Ca^<2+> binding protein / カルシウム / Thyroid hormone / Myogenesis / Calpactin / Gelsolin / Vinculin / Filamin / Alpha-actinin / 分化 / 筋形成 / 収縮調節タンパク / フィラミン / ビンクリン / ゲルゾリン / α-アクチニン / 筋収縮 / drug affinity chromatography / molecular pharmacology / tranilast / 36-kDa MAGP / elastin / アフィニティクロマトグラフィー / エラスチン繊維 / ミクロファイブリル / 肥厚性瘢痕 / 分子薬理学 / ケロイド / トラニラスト / elasith / ミクロフィブリン / 染色体異常 / カルシウムイオン / elasitn / 細胞内情報伝達 / 血管 / 分子プローブ / EFハンド蛋白質 / カルシウム信号 / Calcium signal network / Calcium binding protein / EF-hand protein / Annexin / Calcium Signaling / カルシウム結合タンパク質 / EFーハンドタンパク質 / カルシウムシグナル / カルシウムシグナルネットワ-ク / カルシウム受容蛋白質 / EFーハンド蛋白質 / アネキシン / 新しいカルシウム情報伝達系 / EGF受容体 / リポコルチン / カルシウムイオンによる調節 / リン脂質 / 細胞膜 / 細胞骨格 / アクチン制御タンパク / 分子シャペロン / Tetratricopeptide repeat / Calmodulin / S100蛋白質 / プロテインキナーゼ / 薬理学 / 創薬 / 分子標的薬 / シグナル伝達 / バイオテクノロジー / 生体分子 / 神経科学 … More Except Principal Investigator CaM-KK / Clostridium perfringens / p35 / カルモデュリン / シグナル伝達 / 細胞内カルシウム / Epsilon-toxin / CREB / Receptor / ε毒素 / Calbrain / calbrain / Cdk5 / Protein phosphorylation / Calmodulin / Numbl / Numb / CaM-KI / Signal transduction / Intracellular calcium / MLCK-A / STO-609 / 脂質ラフト / Histopathology / MDCK cell / Nephrotoxicity / Lipid rafts / CaM-kinase / CaM-キナーゼ / リン酸化酵素カスケード / 細胞内情報伝達 / NMDA / S-100 / LTP / CaM kinase II / 脳 / MAGP-36 / PDX-1 / RNA editing / アルツハイマー脳 / カルモジュリン依存性リン酸化酵素 / Protein kinase / Protein kinase inhibitor / KN-62 / カルモデュリンキナ-ゼII / KNー62 / プロテインキナ-ゼ / 蛋白質リン酸化反応 / ロイコトリエン / 血管平滑筋 / カルシウム / CaMKK / CaM-キナーゼカスケード / CaM-kinase cascade / タンパク質リン酸化 / Sphingomyelin / Ganglioside / Platelet aggregation / Lipid raft / Alpha-toxin / セラミド / スフィンゴ糖脂質 / 脂質クラフト / イプシロン毒素 / 血小板 / スフィンゴミエリン / ガングリオシド / 血小板凝集 / α毒素 / ウエルシュ菌 / タンパク質リン酸化酵素阻害剤 / タンパク質リン酸化酵素 / two-hybrid system / humanin / focal segmental glomerulosclerosis / puromycin aminonucleoside / nephrotic syndrome / actinin-4 / filtration barrier / glomerulus / ネフローゼ惹起物質 / two-hybrid法 / ヒューマニン / 巣状分節状糸球体硬化症 / ピューロマイシンアミノヌクレオシド / ネフローゼ症候群 / アクチニン-4 / 濾過バリアー / 糸球体 / Immunohistochemsitry / 膜孔形成型毒素 / モノクローナル抗体 / 腸性毒素血症 / 構造解析 / ウェルシュ菌 / Immunohistochemistry / Histoparhology / C.elegans / Protein Kinase cascade / Sgnal Transduction / Intracellalr Calcium / 線虫 / 細胞内カルシウ / Signal Induction / S100 proteins / Antiallergic Drug / S100蛋白 / シャペロン / 熱ショック蛋白 / S-100蛋白 / 抗アレルギー薬 / alcoholism / hypothermia / brain / S100 / NMR / calcineurin / calmodulin-dependent protein kinase II / Ca^<2+> / 記憶 / カルシウム結合蛋白質 / アルコール依存症 / 低体温 / Membrane solubilization / Immunostaining / Synaptosome / Toxin complex / Epsilon-Toxin / 膜可溶化 / 免疫染色 / シナプトソーム / 毒素複合体 / レセプター / immunosuppressant / neuropeptide Y receptor / Presenilin / brain ischemia / glutamate receptor / GABAトランスポーター / カッパーオピオイドアゴニスト / 成長ホルモン促進ペプチド / p33ING1 / 情報伝達クロストーク / クロストーク / 情報伝達 / ライディッヒ細胞 / 低体温法 / 虚血 / 海馬神経細胞 / 免疫抑制剤 / ニューロペプチドY受容体 / Presenilin-1 / 脳虚血 / グルタミン酸受容体 / neurofilament / tau-protein / neuronal degeneration / Alzheimer's disease / plasticity / phosphorylation / cyclin-dependent kinase / ニューロフィラメント / タウ蛋白質 / 神経変性 / アルツハイマー病 / 可塑性 / リン酸化 / サイクリン依存性キナーゼ5 / calmodulin-dependent enzyme / ecalectin / ischemic neuronal death / kindlling / neuronal cell / calcium / 網膜 / タウ / 長期記憶増強 / リンホカイン / RU-51599 / 老化促進モデルマウス / 脳血管関門 / 成長ホルモン / カルモジュリン依存性酵素 / エカレクチン / 虚血性神経細胞死 / キンドリング / 脳神経細胞 / Inhibitor Data Base / Protein Kinase Inhibitor / 阻害剤デ-タベ-ス / プロテインキナ-ゼ阻害剤 / 阻害剤データベース / プロテインキナーゼ阻害剤 / プロテインキナーゼ / H-89 / EIA / Protein kinase C / CaM-kinase II / Ca^<2+>-dependent protein kinase / 特異的阻害剤 / Cキナ-ゼアイソザイムの細胞特異的発現 / エンザイムイムノアッセイ / Cキナ-ゼアイソザイム / MARCKS / ACAMPー81 / GABA放出 / 長期増強現象 / ζ型Cキナ-ゼ / δ型Cキナ-ゼ / Aーキナ-ゼ / 蛋白質リン酸化酵素阻害剤 / Hー89 / 酵素抗体法 / Cーキナ-ゼ / カルシウム依存性蛋白質リン酸化酵素 / Protein Kinase / Ca^<2+> binding protein (s) / Myosin light chain phosphorylation / カルバスクリン / カルギザリン / カルシウム結合蛋白 / ミオシン脱リン酸化酵素 / Ca^<2+>結合蛋白質 / ミオシン軽鎖リン酸化反応 / カルモジュリン遺伝子 / リポコルチン / カルデスモン / ゲルゾリン / Ca調節 / カルパクチン / ゲルゾリンファミリー / ラッチ機構 / キャッチ機構 / 平滑筋ミオシン / カルシウム依存性細胞機能 / カルシウム依存性キナーゼ / 情報伝達機構 / Wolframin症候群 / MS / LC-MS / WFS1 / 海馬 / 樹状突起 / カルシウム情報伝達 / シナプス / LC-MS/MS / 自己リン酸化 / 変異体 / ATPアナログ / Syndapin I / タンパク質リン酸化反 / LC-MS/ MS / GST / 機能プロテオミクス / PRG-1 / Wolframin / CaM-KIV / タンパク質リン酸化反応 / SAD-キナーゼ / CaMKKCaM-KIV Less

Comprehensive identification and signal transduction analysis of calmodulin-targets by functional proteomics
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
Identification and characterization of a novel target for CaM-kinase cascade
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
The development of the molecular target drugs for intracellular calcium signal pathwayPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kagawa University
Analysis of calmodulin-kinase cascade by using functional proteomics.
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
A study on the mechanism underlying the action of Clostridium perfringens alpha- and epsilon-toxins to membrane lipid rafts
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  KAGAWA UNIVERSITY
  香川大学(医学部)
Interaction between glomerular filtration barrier component actinin-4 and nephrosis-inducing factors
- Principal Investigator
  
  WAKUI Hideki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
Physiological function of calcium/calmodulin-dependent protein kinase cascade
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University(Faculty of Medicine)
Study on structure biology and molecular pathology of Clostridium perfringens epsilon-toxin
- Principal Investigator
  
  OKABE akinobu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Interaction of S100 Proteins with the Antiallergic Drugs in human mastcells
- Principal Investigator
  
  KUBOTA yasuo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kagawa Medical University
Regulation of gene expression mediated by Ca^<2+>/calmodulin-dependent protein kinase cascade
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa Medical University
Studies on neurotropism of Clostridium perfringens epsilon-toxin and molecular mechanism of its toxicity toward neuronal cells
- Principal Investigator
  
  OKABE Akinobu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kagawa Medical University
Neuron specific calcium-binding Protein, calbrain, is involved in memory formation.
- Principal Investigator
  
  TOKUDA Masaaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  KAGAWA MEDICAL UNIVERSITY
ELUCIDATION OF THE MOLECULAR MECHANISM OF KELOIDS AND HVPERTROPHIC SCARS USING SPECIFIC MOLECULAR PROBESPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji, SHISHIBORI Tsuyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  KAGAWA MEDICAL UNIVERSITY
Role of cyclin-dependent kinase 5 in Alzheimer's brain.
- Principal Investigator
  
  TOKUDA Masaaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Neuroscience in general
- Research Institution
  Kagawa Medical University
Cross-talk regulation in multiple signaling systems
- Principal Investigator
  
  TAKAHARA Jiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Pathobiological role of 36 kDa microfibril-associated glycoprotein in Smith-Magenis syndrome.Principal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Elucidation of the mechanisms of the impairment of functional neuron networks and establishment of the therapeutic strategies.
- Principal Investigator
  
  NAGAO Seigo, 入野昭三
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagawa Medical University
Molecular pharmacology of 36kDa microfibril associated glycoprotein (36kDa-MAGP)Principal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kagawa Medical School
The Development of the Strategy for the Presumption of the Tertiary Structure of Protein Kinases by Specific Inhibitors
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
Functional Modification of Calcium Dependent Proteins by PhosphorylationPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Nagoya University
Unification and reconstruction of myosin phosphorylation theory on contractile response of smooth muscle and nonmuscle cells.
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
The role of Ca^<2+>-dependent protein kinases in central nervous system in health and diseases.
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
カルシウムによる細胞応答の分子機構
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Mie University
血管平滑筋・内皮細胞における収縮調節タンパクの生化学的研究Principal Investigator
- Principal Investigator
  
  小林良二
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Akita University
血管平滑筋収縮蛋白の制御
- Principal Investigator
  
  野々村禎昭
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
血管平滑筋収縮蛋白の制御
- Principal Investigator
  
  野々村禎昭
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
Hormonal Influence on actin-binding protein expression in muscle and non-muscle cellsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Ryoji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Akita University, School of medicine

All 2011 2010 2009 2008 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Exendin-4 regulates GLUT2 expression via the CaMKK/ CaMKIV pathway in a pancreatic beta-cell line2011
- Author(s)
  Chen K, Yu X, Murao K, Imachi H, Li J, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T, and Tokumitsu H
- Journal Title
  
  Metabolism
  
  Volume: 60 Pages: 579-585
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Generation of Autonomous Activity of Ca^<2+>/ Calmodulin-Dependent Protein Kinase Kinaseβby Autophosphorylation2011
- Author(s)
  Tokumitsu H, Hatano N, Fujimoto T, Yurimoto S, and Kobayashi R
- Journal Title
  
  Biochemistry
  
  Volume: 50 Pages: 8193-8201
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Identification of a novel CaMKK substrate2011
- Author(s)
  Fujimoto T, Hatano N, Nozaki N, Yurimoto S, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochem. Biophys. Res. Comm
  
  Volume: 410 Pages: 45-51
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats2010
- Author(s)
  Shimamoto S, Kubota Y, Tokumitsu H, and Kobayashi R
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 1119-1125
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Regulation of nuclear localization signal-importin・interaction by Ca^<2+>/ S100A62010
- Author(s)
  Takata M, Shimamoto S, Yamaguchi F, Tokuda M, Tokumitsu H, and Kobayashi R
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 4517-4523
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/ CaMKIV pathway2010
- Author(s)
  Li J, Murao K, Imachi H, Masugata H, Iwama H, Tada S, Zhang GX, Kobayashi R, Ishida T, and Tokumitsu H
- Journal Title
  
  J. Cell. Mol. Med
  
  Volume: 14 Pages: 1083-1087
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Identification and characterization of PRG-1 as a neuronal calmodulin-binding protein2010
- Author(s)
  Yurimoto S, Fujimoto T, Ohara N, Kobayashi R, and Sakagami H
- Journal Title
  
  Biochem. J
  
  Volume: 431 Pages: 81-91
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Exendin-4 regulates glucokinase expression by CaMKK/ CaMKIV pathway in pancreatic beta-cell line2009
- Author(s)
  Murao K, Li J, Imachi H, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T, and Tokumitsu H
- Journal Title
  
  Diabetes Obes. Metab
  
  Volume: 11 Pages: 939-946
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Exendin-4 regulates Glucokinase expression via CaMKK/CaMKIV pathway in pancreatic β cell line2009
- Author(s)
  Murao K, Li J, Imachi H, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T and Tokumitsu H
- Journal Title
  
  Diabetes, Obesity and Metabolism
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] dentification and Characterization of Wolframin, the Product of the Wolfram Syndrome Gene (WFS1), as a Novel Calmodulin-Binding Protein2009
- Author(s)
  Yurimoto S, Hatano N, Tsuchiya M, Kato K, Fujimoto T, Masaki T, Kobayashi R. and Tokumitsu H
- Journal Title
  
  Biochemistry 48(18)
  
  Pages: 3946-3955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] Identification and characterization of wolframin, the product of the wolfram syndrome gene(WFS1), as a novel calmodulin-binding protein2009
- Author(s)
  Yurimoto S, Hatano N, Tsuchiya M, Kato K, Fujimoto T, Masaki T, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochemistry
  
  Volume: 48 Pages: 3946-3955
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins Hsp90/Hsp70-organizing protein and kinesin-light chain2008
- Author(s)
  Shimamoto S, Takata M, Tokuta M, Oohira F, Tokumitsu H, and Kobayashi R
- Journal Title
  
  Journal of Biological Chemistry 83(42)
  
  Pages: 28246-28258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570134
[Journal Article] Differential gene expression of 36-kDa microfibril associated glycoprotein in rat organs2008
- Author(s)
  Toyoshima T, Ishida T, Nishi N, Kobayashi R, Nakamura T, and Itano T
- Journal Title
  
  Cell and Tissue Res 332(2)
  
  Pages: 271-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] Activation of SAD Kinase by Ca2+/Calmodulin-dependent Protein Kinase Kinase2008
- Author(s)
  Fujimoto T, Yurimoto S, Hatano N, Nozaki N, Sueyoshi N, Kameshita I, Mizutani A, Mikoshiba K, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochemistry 47 (13)
  
  Pages: 4151-4159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90 /Hsp70-organizing protein and kinesin- light chain2008
- Author(s)
  Shimamoto S, Takata M, Tokuta M, Oohira F, Tokumitsu H, and Kobayashi R
- Journal Title
  
  Journal of Biological Chemistry 83(42)
  
  Pages: 28246-28258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] Activation of SAD Kinase by Ca2+/Calmodulin-dependent Protein Kinase Kinase2008
- Author(s)
  Fujimoto T, Yurimoto S, Hatano N, Nozaki N, Sueyoshi N, Kameshita I, Mizutani A, Mikoshiba K, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochemistry 47(13)
  
  Pages: 4151-4159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570134
[Journal Article] The Role of Calcium/Calmodulin -Dependent Protein Kinase Cascade on MIP-1a Gene Expression of ATL Cells2008
- Author(s)
  Matsumoto K, Murao K, Imachi H, Nishiuchi T, Cao W M, Yu X, Li J, Ahmed R A M, Iwama H, Kobayashi R, Tokumitsu H, and Ishida T
- Journal Title
  
  Experimental Hematology 36(4)
  
  Pages: 390-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300123
[Journal Article] Phosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2.2006
- Author(s)
  H.Tokumitsu, N.Hatano, S.Yokokura, Y.Sueyoshi, N.Nozaki, R.Kobayashi
- Journal Title
  
  FEBS Letters 580(24)
  
  Pages: 5797-5801
- NAID
  120007015428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570115
[Journal Article] Phosphorylation of Numb family proteins. : Possible involvement of Ca^<2+>/calmodulin-dependent protein kinases.2005
- Author(s)
  H.Tokumitsu, N.Hatano, H.Inuzuka, Y.Sueyoshi, S.Yokokura, T.Ichimura, N.Nozaki, R.Kobayashi
- Journal Title
  
  Journal of Biological Chemistry 280(42)
  
  Pages: 35108-35118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570115
[Journal Article] Interaction of the spectrin-like repeats of alpha-actinin-4 with humanin peptide2004
- Author(s)
  Kigawa A, Wakui H, Maki N, Okuyama S, Masai R, Ohtani H, Komatsuda A, Suzuki D, Toyoda M, Kobayashi R, Sawada K
- Journal Title
  
  Clin Exp Nephrol 8-4
  
  Pages: 331-338
- NAID
  10014091272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571010
[Journal Article] Renal alpha-actinin-4 : Purification and puromycin aminonucleoside-binding property2003
- Author(s)
  Goto H, Wakui H, Komatsuda A, Ohtani H, Imai H, Sawada K, Kobayashi R
- Journal Title
  
  Nephron Exp Nephrol 93-1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571010
[Presentation] Identification of a novel target for Ca^<2+>/ CaM-dependent protein kinase kinase by using an ATP analogue2011
- Author(s)
  藤本智仁, 波多野直哉, 野崎直仁, 横倉(揺本)沙紀, 小林良二, 徳光浩
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] Regulatory Mechanism of CaMKK by Autophosphorylation2011
- Author(s)
  徳光浩、横倉(揺本)沙紀、波多野直哉、藤本智仁、小林良二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] PRG-1(plasticity related gene 1), a novel neuronal calmodulin-binding protein2010
- Author(s)
  徳光浩、波多野直哉、土屋光正、横倉(揺本)沙紀、藤本智仁、小原直樹、小林良二、阪上洋行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会,合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] Ca^<2+>/ calmodulin-dependent protein kinae kinase ca utilize GTP as a phosphate donor2010
- Author(s)
  藤本智仁、小林良二、徳光浩
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会,合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] S100タンパク質はCHIP(E3)を介したユビキチン化を制御する2010
- Author(s)
  嶋本聖子、小林良二
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会,合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570143

1. TOKUMITSU Hiorshi (20237077)

# of Collaborated Projects: 10 results

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2. TOKUDA Masaaki (10163974)

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55. HANS van de

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KOBAYASHI Ryoji 小林 良二

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The development of the molecular target drugs for intracellular calcium signal pathwayPrincipal Investigator

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ELUCIDATION OF THE MOLECULAR MECHANISM OF KELOIDS AND HVPERTROPHIC SCARS USING SPECIFIC MOLECULAR PROBESPrincipal Investigator

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KOBAYASHI Ryoji 小林良二