Yokoyama Shigeyuki 横山茂之

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YOKOYAMA Shigeyuki 横山茂之

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Researcher Number	00159229
Other IDs
Affiliation (Current)	2024: 信州大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2024: 信州大学, 医学部, 特任教授 2018 – 2023: 国立研究開発法人理化学研究所, 科技ハブ産連本部, 特別招聘研究員 2016 – 2017: 国立研究開発法人理化学研究所, 横山構造生物学研究室, 上席研究員 2016: 独立行政法人理化学研究所, 横山構造生物学研究室, 上席研究員 2015: 国立研究開発法人理化学研究所, その他部局等, 上席研究員 … More 2015: 理化学研究所, 横山構造生物学研究室, 上席研究員 2013 – 2014: 独立行政法人理化学研究所, 横山構造生物学研究室, 上席研究員 2013: 独立行政法人理化学研究所, その他部局等, 研究員 2012: 独立行政法人理化学研究所, その他部局等, 領域長 2010 – 2012: The University of Tokyo, 生命分子システム基盤研究領域, 領域長 2010 – 2011: The Institute of Physical and Chemical Research, 研究員 1993 – 2009: 東京大学, 大学院・理学系研究科, 教授 2007: The University of Tokyo, Graduate School of Science, Professor 2007: The University of Tokyo, Graduate School of Science, Professor 2006: 東京大学, 大学院理学系研究科, 教授 1998 – 1999: 東京大学, 理学部, 教授 1996: 理化学研究所, 細胞情報伝達研究室, 主任研究員 1994 – 1996: 東京大学, 理学系研究科, 教授 1991 – 1994: 東京大学, 理学部, 教授 1986 – 1991: 東京大学, 理学部, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Structural biochemistry / Biological Sciences / Biophysics / Structural biochemistry Except Principal Investigator 生物物性学 / Molecular biology / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 48030:Pharmacology-related / Medium-sized Section 53:Organ-based internal medicine and related fields … More / Metabolomics / Cardiovascular medicine / Biological Sciences / Neuroscience in general / Biophysics / 天然物有機化学 / Living organism molecular science / Biological Sciences / Science and Engineering / Structural biochemistry / 分子遺伝学・分子生理学 / 物質生物化学 Less
Keywords	Principal Investigator NMR / tRNA / RNA / 立体構造 / X線結晶構造解析 / Ras / アミノアシルtRNA合成酵素 / Raf-1 / RalGDS / PC12細胞 … More / 高次構造 / タンパク質 / RNAポリメラーゼ / 転写後修飾 / アンチコドン / コドン / 遺伝暗号 / Intermolecular interaction / 相互作用 / mSosl / RGL / 蛋白質 / 免疫学 / リボソーム / 翻訳 / 転写 / X線結晶解析 / Cys-rich domain / 多次元NMR法 / リボザイム / フレ-ムシフト / tRNAアイデンティティ- / 安定同位体標識 / GTP / がん遺伝子 / TCR / MHC / アレルギー・ぜんそく / Artificial genetic code / Transcription / Translation / Crystallography / CENP-B / Vase / 超分子複合体 / RNAヘリカーゼ / セントロメア / 修飾酵素 / Dmc1 / 相同組み換え / 複製 / 人工遺伝子暗号 / 翻訳制御 / LSD1 / RNA修飾 / 人工遺伝暗号 / 結晶構造解析 / RNA-binding protein / 3D structure / X-ray Crystallography / RNAポリメーゼ / リボゾーム / SRP / tmRNA / RNA修飾酵素 / LINE / RNA結合タンパク質 / cell-free protein synthesis / tertiary structure / deuteration / selective labeling / stable-isotope labeling / protein / 安定同定位体標識 / 無細胞タンパク質合成系 / 重水素化 / 選択的標識 / regional polysterism / PC12 cells / Signal transdution / GAP / MAPキナーゼ / PHドメイン / Sos / コンホメーション多形性 / シグナル伝達機構 / Rasタンパク質 / X-ray crystallography / ribosome / ribozyme / splicing / functional structure / RNA触媒(リボザイム) / rRNA / mRNAスプライシング / スプライシング / 機能構造 / 分子認識 / 構造生物学 / 医薬品設計 / ペプチド / HLA / 翻訳開始因子 / 転写因子 / EHドメイン / NMR法 / Raf / シグナル伝達経路 / Cdc42 / Rac / レトロポゾン / RNAスプライシング / RNAの新しい機能 / 部位特異的変異 / cーHaー<ras>___ー遺伝子産物 / フレームシフト / ナンセンス・サプレション / 微量注入 / アザチロシン / 2次元NMR / cーHaーras遺伝子産物 … More Except Principal Investigator NMR / RNA / tRNA / 翻訳調節 / ミトコンドリア / ガングリオシド / 分子擬態 / エクト型酵素 / CD38 / RNA結合蛋白質 / RNAプロセシング / 転写後調節 / ヒト上皮成長因子 / 慢性臓器障害 / 生活習慣病 / 立体構造解析 / 癌 / 心不全 / PDK4 / CD / TRNOE / リボソーム / 修飾ヌクレオシド / ポストゲノム / 高次複合機能 / RNA蛋白質複合体 / ネットワーク / シグナル伝達 / 細胞膜 / NAD / 糖脂質 / リボザイム / 高次構造 / 安定同位体標識 / DNA / 立体構造 / タンパク質 / 水素交換反応 / モルテン・グロビュール状態 / GroEL / シャペロニン / 分子シャペロン / タンパク質の細胞内輸送 / 分子認識 / スプライシング / 進化 / エンテロバクチンモデル / リポソ-ム / αー2ーマクログロブリン / wobbleの法則 / 暗号解読 / コドン使用 / 遺伝暗号 / 代謝 / 血管 / RAMP / 恒常性 / 心臓 / 創薬 / 臓器障害 / 受容体活性調節タンパク / トランスレーショナルリサーチ / 薬理学 / 糖尿病 / in silico解析 / Dynamics of DNA / Structure of bulge loop / Structure of hairpin loop / cro repressor / HU protein / Structure and function of tRNA / Structures of DNA / Hu-DNA複合体 / Croリプレッサー / ヘアピンループ / 制限酵素 / X線回析 / DNAの分子運動 / バルジループの構造 / Cro蛋白質ヘアピンループの構造 / Hu蛋白質 / tRNAの構造と機能 / DNA構造の多形 / Rolyamine / Extreme Thermophile / Artificial Amino Acid / Neoprotein / Modified Nucleoside / Anticodon / 部位特異変異体遺伝子 / タンパク質合成システム / 好酸好熱菌 / アミノ酸 / 遺伝コード / アミノアシルtRNA合成酵素(ARS) / ポリペプチド鎖延長因子 / 非天然アミノ酸 / コドン / ポリアミン / 転写後修飾 / 超タンパク質 / 高度好熱菌 / アンチコドン / アミノアシルtRNA合成酵素 / Post-transcriptional Control / Translational Control / RAN Interference / Noncoding RNA / Molecular Mimicry / RNP Complex / Network / RNA干渉 / ノンコーディングRNA / RNA-binding protein / life of mRNA / stop codon / molecular mimicry / ribosome / posttranscriptional control / translational control / 終止コドン / mRNA動態 / 終止コトン / 転写後制御 / Muscarine / Acetylcholine / G Protein / Transmitter / Large-Scale Purification / Conformation / Receptor / 伝達物質 / レセプター / ムスカリン / アセチルコリン / Gタンパク質 / 神経伝達物質 / 大量発現 / 受容体 / Ras interacting site / NMR Analysis of Raf / Double labeling of protein with stable isotopes / E.coli coupled transcription and translation system / Improvement of translation efficiency / Ribosome inactivating protein / Cell-free protein synthesizing system / 転写・翻訳共役反応 / 連続反応装置 / 大腸菌無細胞蛋白質合成系 / 小麦胚芽無細胞蛋白質合成系 / 連続式無細胞蛋白質合成 / 翻訳活性の効率化 / RNA N-グリコシダーゼ / ロボソームRNA / 無細胞蛋白質合成 / 安定同位体元素2重標識Ras蛋白質 / コムギ胚芽無細胞系の翻訳反応効率化 / Ras相互作用部位の構造解析 / NMRによるRaf / 安定同位体元素2重標識蛋白質 / 転写翻訳共役大腸菌無細胞系 / コムギ胚芽無細胞系翻訳反応効率化 / リボソームの不活性化蛋白質 / 無細胞蛋白質合成システム / Biosensor / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫病 / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / sx1 protein / stable isotope labeling / base pairing / modified nucleoside / alternative splicing / splicing / ミトコンドリアtRNA / mRNAスプライシング / rRNA / nRNAスプライシング / 機能構造 / 蛋白質 / 塩基対合 / オルタナテイブスプライシング / 動的天然物化学 / 光受容膜 / 生合成 / イソプレノイド / コドン認識 / 構造解析 / 結晶化 / プラズマ / 自己免疫病 / HLA立体構造 / ゲノム / 疾病 / HLA / データベース / 疾病感受性 / 自己免疫疾患 / 移植 / 疾患抵抗性 / 疾患感受性 / ゲノム多様性 / ＨＬＡ / 生態生命情報学 / バイオテクノロジー / ナノバイオ / 自己組織化 / 生体生命情報学 / DNAコンピュータ / 情報発現 / ニコチンアミドアデニンジヌクレオチド / リコーディング / 細胞内輸送 / 遺伝子発現 / mRNA / RNA-蛋白質複合体 / SELEX法 / 構造-機能相関 / 高次生命現象 / mRNA動的構造 / 情報発現調節機能 / 触媒機能 / RNA動的機能 / 発現系 / 部位特異的標識 / 無細胞タンパク質合成系 / NMRスペクトル / パルスラベル法 / ストップトフロー法 / DNA結合ドメイン / Myb / がン遺伝子産物 / X線結晶解析 / α2-マクログロブリン / カドヘリン / 細胞接着 / リポソーム / 膜タンパク質移行 / 機能発現 / 制御RNAシグナル / 翻訳制御 / RNA触媒 / 生命の起原 / 転移RNA / イントロン / RNAワ-ルド / B16メラノ-マ / αNーカテニン / カドヘレン / 血液型抗原 / RNA機能 / ペプチド / 動物細胞 / シクロファン / ガドヘレン / tRNA identity Less

AM-RAMPシステムの全容解明と、生活習慣病・慢性臓器障害への治療応用
- Principal Investigator
  
  新藤隆行
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Shinshu University
受容体活性調節システムによる生体内恒常性制御機構の解明と創薬への展開
- Principal Investigator
  
  新藤隆行
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Shinshu University
Development of a novel PDK4 inhibitor as a new therapeutic agent for heart failure
- Principal Investigator
  
  Nagai Ryozo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Jichi Medical University
Structural analysis of neo-selfPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
Improvement of the PDK4 inhibitors based on the tertiary structure analysis and application for the treatment of heart failure
- Principal Investigator
  
  Nagai Ryozo
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Building and establishing platform technologies for Structure Based Drug Design targeting AdipoR
- Principal Investigator
  
  Iwabu Miki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Plasma-Assisted Biological Macromolecular Crystallization
- Principal Investigator
  
  ITO Tsuyohito
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
Integrated redearch for HLA disease and evolution
- Principal Investigator
  
  SASAZUKI Takehiko
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Structural analysis of HLA class I/II moleculesPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Crystallographic studies of macromolecular complexes in transcription and translation : RNA polymerases and the ribosomePrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
  The University of Tokyo
  Tokyo Gakugei University
Structural and functional studies on biological macromolecules involved in the flow of genetic information and the cellular signal transduction.Principal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
形態変化する分子を用いた並行計算と分散計算
- Principal Investigator
  
  萩谷昌己
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Structure of RNA and RNPPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Spatiotemporal Network of RNA Information Flow
- Principal Investigator
  
  NAKAMURA Yoshikazu
- Project Period (FY)
  2001 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
RNA研究の21世紀への展開
- Principal Investigator
  
  中村義一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nihon University
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nihon University
Ras蛋白質によるターゲット活性化のメカニズムPrincipal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nihon University
Rasタンパク質によるターゲット活性化のメカニズムPrincipal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular basis of RNA function
- Principal Investigator
  
  NAKAMURA Yoshikazu
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
無細胞タンパク質合成系を用いた新規のタンパク質安定同位体標識法の開発と応用
- Principal Investigator
  
  KIGAWA Takanori
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
発癌型Rasに特徴的な細胞内情報伝達機構の解析Principal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
RNA機能のフロンティア
- Principal Investigator
  
  渡辺公綱
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
mRNA研究の展開
- Principal Investigator
  
  中村義一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
New stable-isotope labeling methods for structural studiesPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Structural study on the mechanism of the signal transduction mediated by the Ras proteinPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Conformation of the Muscarinic Acetylcholine Receptor
- Principal Investigator
  
  HAGA Tatsuya
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  University of Tokyo
水素交換ラベルと二次元NMRによるタンパク質の膜透過型分子構造の解析
- Principal Investigator
  
  桑島邦博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Developement of a Cell-free protein synthesizing system
- Principal Investigator
  
  ENDO Yaeta
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Ehime University
細胞表層の精密構造認識と機能性制御
- Principal Investigator
  
  砂本順三
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
水素交換ラベルと二次元NMRによるタンパク質の膜透過型分子構造の解析
- Principal Investigator
  
  桑島邦博
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝子調節機構の立体構造とダイナミクスの研究調査
- Principal Investigator
  
  NISHIMURA Yoshifumi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  生物物性学
- Research Institution
  Yokohama City University
水素交換パルスラベルとNMR測定のためのプログラマブル多段混合装置の製作
- Principal Investigator
  
  桑島邦博
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  生物物性学
- Research Institution
  The University of Tokyo
Mechanism of RNA function expression
- Principal Investigator
  
  WATANABE Kimitsuna
- Project Period (FY)
  1992 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
New Scope of RNA Functional StructuresPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Shigeyuki
- Project Period (FY)
  1992 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tokyo
遺伝暗号解読のメカニズムPrincipal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝暗号の可変性
- Principal Investigator
  
  大沢省三
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
細胞表層の精密構造認識と機能制御
- Principal Investigator
  
  砂本順三
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
RNA研究の新しい展開
- Principal Investigator
  
  岡田典弘
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  University of Tsukuba
RNAの動的機能発現の分子機構
- Principal Investigator
  
  中村義一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
RNA機能構造の新視点Principal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  The University of Tokyo
ヒトcーHaーras遺伝子産物の機能発現の分子機構Principal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
遺伝暗号解読のメカニズムPrincipal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝暗号の可変性
- Principal Investigator
  
  大沢省三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
細胞表層の精密構造認識と機能性制御
- Principal Investigator
  
  砂本順三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ヒトcーHaーras遺伝子産物の機能発現の分子機構Principal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
遺伝暗号解読のメカニズムPrincipal Investigator
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
分子認識を目指す動的天然物化学
- Principal Investigator
  
  後藤俊夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  Nagoya University
Versatality of Nucleic Acid Structure and its recognition
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Tokyo College of Pharmacy
Dynamic Structures and Function Control of Protein Synthesis System
- Principal Investigator
  
  MIYAZAWA Tetsuo
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  University of Tokyo

[Book] The Aminoacyl-tRNA Synthetases : Chapter 7 & 82005
- Author(s)
  Yokoyama, S.
- Total Pages
  14
- Publisher
  Landes Bioscience
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Book] The Aminoacyl-tRNA Synthetases: Chapter 7 & 82005
- Author(s)
  Yokoyama, S.
- Total Pages
  14
- Publisher
  Landes Bioscience
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoRl and AdipoR22015
- Author(s)
  Tanabe H,..., Iwata S, Okada-Iwabu M, Iwabu M,..., Yamauchi T, Kadowaki T, and Yokoyama S
- Journal Title
  
  J. Struct. Funct. Genomics
  
  Volume: 16 Issue: 1 Pages: 11-23
- DOI
  10.1007/s10969-014-9192-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032
[Journal Article] Crystal structures of the human adiponectin receptors.2015
- Author(s)
  Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T, Ohsawa N, Hato M, Ogasawara S, Hino T, Murata T, Iwata S, Hirata K, Kawano Y, Yamamoto M, Kimura-Someya T, Shirouzu M, Yamauchi T, Kadowaki T, Yokoyama S
- Journal Title
  
  Nature
  
  Volume: 520 Issue: 7547 Pages: 312-316
- DOI
  10.1038/nature14301
- NAID
  40020952688
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-25711004, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] Structural Basis for the Specific Recognition of the Major Antigenic Peptide from the Japanese Cedar Pollen Allergen Cry j 1 by HLA-DP5.2014
- Author(s)
  Kusano S, Kukimoto-Niino M, Satta Y, Ohsawa N, Uchikubo-Kamo T, Wakiyama M, Ikeda M, Terada T, Yamamoto K, Nishimura Y, Shirouzu M, Sasazuki T, Yokoyama S.
- Journal Title
  
  J Mol Biol.
  
  Volume: 426 Issue: 17 Pages: 3016-3027
- DOI
  10.1016/j.jmb.2014.06.020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133004, KAKENHI-PLANNED-22133005, KAKENHI-PLANNED-22133007, KAKENHI-PLANNED-22133009
[Journal Article] Structural basis of transcription by bacterial and eukaryotic RNA polymerases2012
- Author(s)
  Sekine, S., Tagami, S. and Yokoyama, S.
- Journal Title
  
  Curr. Opin. Struct. Biol.
  
  Volume: 22 Pages: 110-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA Polymerase III2011
- Author(s)
  Ehara, H., Sekine, S. and Yokoyama, S.
- Journal Title
  
  Protein Sci
  
  Volume: 20 Pages: 1558-1565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] A novel conformation of RNA polymerase sheds light on the mechanism of transcription2011
- Author(s)
  Tagami, S., Sekine, S. and Yokoyama, S.
- Journal Title
  
  Transcription
  
  Volume: 2 Pages: 162-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of Thermus thermophilus transcription elongation complex bound to Gfh1.2010
- Author(s)
  Tagami S, Sekine S, Kumarevel T, Yamamoto M, Yokoyama S.
- Journal Title
  
  Acta Crystallogr.Sect F. 66
  
  Pages: 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structural basis for the major role of O-phosphoseryl-tRNA kinase in the UGA-specific encoding of selenocysteine2010
- Author(s)
  Chiba, S., Itoh, Y., Sekine, S. and Yokoyama, S.
- Journal Title
  
  Mol. Cell
  
  Volume: 39 Pages: 410-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structure of Nondiscriminating Glutamyl-tRNA Synthetase from Thermotoga maritime2010
- Author(s)
  Ito, T., Kiyasu, N., Matsunaga, R., Takahashi, S. and Yokoyama, S.
- Journal Title
  
  Acta Crystallogr. D Biol. Crystallogr
  
  Volume: 66(7) Pages: 813-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions2010
- Author(s)
  Ito, T. and Yokoyama, S.
- Journal Title
  
  Nature
  
  Volume: 467 Pages: 612-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of Methanocaldococcus jannaschii Trm4 complexed with sinefungin2010
- Author(s)
  Kuratani, M., Hirano, M., Goto-Ito, S., Itoh, Y., Hikida, Y., Nishimoto, M., Sekine, SI., Bessho, Y., Ito, T., Grosjean, H. and Yokoyama, S.
- Journal Title
  
  J. Mol. Biol
  
  Volume: 401(3) Pages: 323-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structurally Designed Trans-2-phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM12010
- Author(s)
  Mimasu, S., Sato, S., Umezawa, N., Higuchi, T., Umehara, T. and Yokoyama, S.
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 6494-6503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structural basis for the major role of O-phosphoseryl-tRNA kinase in the UGA-specific encoding of selenocysteine.2010
- Author(s)
  Chiba, S., Itoh, Y., Sekine, S., Yokoyama, S.
- Journal Title
  
  Mol.Cell 39
  
  Pages: 410-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein.2010
- Author(s)
  Tagami, S., Sekine, S., Kumarevel, T., Hino, N., Murayama, Y., Kamegamori, S., Yamamoto, M., Sakamoto, K., Yokoyama, S.
- Journal Title
  
  Nature 468
  
  Pages: 978-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] The C-terminal BAG Domain of BAG5 Induces Conformational Changes of the Hsp70 Nucleotide-binding Domain for ADP-ATP Exchange2010
- Author(s)
  Arakawa, A., Handa, N., Ohsawa, N., Shida, M., Kigawa, T., Hayashi, F., Shirouzu, M. and Yokoyama, S.
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 309-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein2010
- Author(s)
  Tagami, S., Sekine, S., Kumarevel, T., Hino, N., Murayama, Y., Kamegamori, S., Yamamoto, M., Sakamoto, K. and Yokoyama, S.
- Journal Title
  
  Nature
  
  Volume: 468 Pages: 978-982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structure of an archaeal homologue of the bacterial Fmu/RsmB/RrmB rRNA cytosine 5-methyltransferase2010
- Author(s)
  Hikida, Y., Kuratani, M., Bessho, Y., Sekine, SI. and Yokoyama, S.
- Journal Title
  
  Acta Crystallogr. D Biol. Crystallogr
  
  Volume: 66(12) Pages: 1301-1307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.2010
- Author(s)
  Ito, T., Yokoyama, S.
- Journal Title
  
  Nature 467
  
  Pages: 612-616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Codon Reassignment in the Escherichia coli Genetic Code2010
- Author(s)
  Mukai, T., Hayashi, A., Iraha, F., Sato, A., Ohtake, K., Yokoyama, S. and Sakamoto, K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Pages: 8188-8195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of Thermus thermophilus transcription elongation complex bound to Gfh12010
- Author(s)
  Tagami, S., Sekine, SI., Kumarevel, T., Yamamoto, M. and Yokoyama, S.
- Journal Title
  
  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun
  
  Volume: 66(1) Pages: 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization.2009
- Author(s)
  Naganuma, M., Sekine, S., Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 106
  
  Pages: 8489-8494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization2009
- Author(s)
  Naganuma, M., Sekine, SI., Fukunaga, R. and Yokoyama, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 106 Pages: 8489-8494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of theαsubunit of human translation initiation factor 2B2009
- Author(s)
  Hiyama, T. B., Ito, T., Imataka, H. and Yokoyama, S.
- Journal Title
  
  J. Mol. Biol
  
  Volume: 392 Pages: 937-951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of the α subunit of human translation initiation factor 2B.2009
- Author(s)
  Hiyama, T.B., Ito, T., Imataka, H., Yokoyama, S.
- Journal Title
  
  J.Mol.Biol. 392
  
  Pages: 937-951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs2009
- Author(s)
  Itoh, Y., Sekine, SI., Matsumoto, E., Akasaka, R., Takemoto, C., Shirouzu, M. and Yokoyama, S.
- Journal Title
  
  J. Mol. Biol
  
  Volume: 385 Pages: 1456-1469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal structure of human selenocysteine tRNA2009
- Author(s)
  Itoh, Y., Chiba, S., Sekine, SI. and Yokoyama, S.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 37 Pages: 6259-6268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation2009
- Author(s)
  Goto-Ito, S., Ito, T., Kuratani, M., Bessho, Y. and Yokoyama, S.
- Journal Title
  
  Nat. Struct. Mol. Biol
  
  Volume: 16 Pages: 1109-1115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Crystal Structure of the alpha subunit of human translation initiation factor 2B2009
- Author(s)
  Hiyama, T.B., Ito, T., Imataka, H., Yokoyama, S
- Journal Title
  
  J Mol Biol 392
  
  Pages: 937-951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Alteration of enzymatic properties of cell-surface antigen CD38 by agonistic anti-CD38 antibodies that prolong B cell survival and induce activation2008
- Author(s)
  Hara-Yokoyama, M., Kimura, T., Kaku, H., Wakiyama, M., Kaitsu, Y., Inoue, M., Kusano, S., Shirou, M., Yokoyama, S., katada, T., Hirabayashi, Y., Takatsu, K., Yanagishita, M.
- Journal Title
  
  Int Immunopharmacol 8(1)
  
  Pages: 59-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Transplantation of a tyrosine editing domain into a tyrosyl-tRNA synthetase variant enhances its specificity for a tyrosine analog2008
- Author(s)
  Oki, K., Sakamoto, K., Kobayashi, T., Sasaki, H. M. and Yokoyama, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 105 Pages: 13298-13303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247008
[Journal Article] Alteration of enzymatic properties of cell-surface antigen CD38 by agonistic anti-CD38 antibodies that prolong B cell survival and induce activation2008
- Author(s)
  Hara-Yokoyama, M.
- Journal Title
  
  Int Immunopharmacol 8
  
  Pages: 59-70
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase2008
- Author(s)
  Yanagisawa, T., Ishii, R., Fukunaga, R., Kobayashi, T., Sakamoto, K., Yokoyama, S.
- Journal Title
  
  j Mol Biol in press
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2^1-O-methylcytidine at position 56 of tRNA2008
- Author(s)
  Kuratani, M., Bessho, Y., Nishimoto, M., Grosjean, H., Yokoyama, S.
- Journal Title
  
  J Mol Biol 375(4)
  
  Pages: 1064-1075
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A2008
- Author(s)
  Mimasu, S., Sengoku, T, Fukuzawa, S., Umehara, T., Yokoyama, S.
- Journal Title
  
  Biochem Biophys Res Commun 366(1)
  
  Pages: 15-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNA(Ile).2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Biochemistry 46(17)
  
  Pages: 4985-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes2007
- Author(s)
  Ishii, R., Minagawa, A., Takaku, H., Takagi, M., Nashimoto, M., Yokoyama, S
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 8)
  
  Pages: 637-641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structure of the AIaX-M trans-editing enzyme from Pyrococcus horikoshii2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 63(Pt 3)
  
  Pages: 390-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary X-ray crystallographic study of alanyl-tRNA synthetase from the archaeon Archaeoglobus fulgidus.2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 3)
  
  Pages: 224-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNA(lle)2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Biochemistry 46(17)
  
  Pages: 4985-4996
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Site-specific incorporation of non-natural amino acids into proteins in mammalian cells with an expanded genetic code2007
- Author(s)
  Hino, N., Hayashi, A., Sakamoto, K., Yokoyama, S.
- Journal Title
  
  Nat Protoc 1(6)
  
  Pages: 2957-2962
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine2007
- Author(s)
  Kuratani, M., Yoshikawa, Y., Bessho, Y., Higashijima, K., Ishii, T., Shibata, R, Takahashi, S., Yutani, K., Yokoyama, S.
- Journal Title
  
  Structure 15(12)
  
  Pages: 1642-1653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis2007
- Author(s)
  Shimada, A., Niwa, H., Tsujita, K., Suetsugu, S., Nitta, K., Hanawa-Suetsugu, K., Akasaka, R., Nishino, Y., Toyama, M., Chen, L., Liu, Z. J., Wang, B. C., Yamamoto, M., Terada, T., Miyazawa, A., Tanaka, A., Sugano, S., Shirouzu, M., Nagayama, K., Takenawa, T., Yokoyama, S.
- Journal Title
  
  Cell 129(4)
  
  Pages: 761-772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat Struct Mol Biol 14(4)
  
  Pages: 272-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea : crystal structure of Sep-tRNA : Cys-tRNA synthase from Archaeoglobus fulgidus2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biol 370(1)
  
  Pages: 128-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Site-specific incorporation of non-natural amino acids into proteins in the mammalian cells with an expanded genetic code2007
- Author(s)
  Nobumasa Hino, Akiko Hayashi, Kensaku Sakamoto, Shigeyuki Yokoyama
- Journal Title
  
  Nature protocols 1
  
  Pages: 2957-2962
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] The putative DNA-binding protein Stol2a from the thermoacidophilic archaeon Sulfolobus tokodaii contains intrachain and interchain disulfide bonds2007
- Author(s)
  Shinkai, A., Sekine, S., Urushibata, A., Terada, T., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J Mol Biol 372(5)
  
  Pages: 1293-1304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The crystal structure of leucyl/phenylalanyl-tRNA-protein transferase from Escherichia coli.2007
- Author(s)
  Dong, X., Kato-Murayama, M., Muramatsu, T., Mori, H., Shirouzu, M., Bessho, Y., Yokoyama, S.
- Journal Title
  
  Protein Sci. 16
  
  Pages: 528-534
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA2007
- Author(s)
  Bessho, Y., Shibata, R., Sekine, S., Murayama, K., Higashijima, K., Hori-Takemoto, C., Shirouzu, M., Kuramistsu, S., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 104(20)
  
  Pages: 8293-8298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis.2007
- Author(s)
  Goto-Ito, S., Ishii, R., Ito, T., Shibata, R., Fusatomi, E., Sekine, S. I., Bessho, Y., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 63 (Pt10)
  
  Pages: 1059-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat Struct Mol Biol 14(4)
  
  Pages: 272-279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction.2007
- Author(s)
  Kaminishi, T., Wilson, D. N., Takemoto, C., Harms, J. M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S.
- Journal Title
  
  Structure 15(3)
  
  Pages: 289-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm52007
- Author(s)
  Goto-lto, S., Ito, T., Ishii, R., Muto, Y., Bessho, Y., Yokoyama, S.
- Journal Title
  
  Proteins (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription2007
- Author(s)
  Wei, Y., Liu, S., Lausen, J., Woodrell, C., Cho, S., Biris, N., Kobayashi, N., Wei, Y., Yokoyama, S., Werner, M. H.
- Journal Title
  
  Nat Struct Mol Biol 14(7)
  
  Pages: 653-661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.2007
- Author(s)
  Connell, S.R., Takemoto, C., Wilson, D.N., Wang, H., Murayama, K., Terada, T., Shirouzu, M., Rost, M., Schuler, M., Jan, G., Marylena, D., Mielke, T., Fucini, P., Yokoyama, S., Spahn, C.M.T.
- Journal Title
  
  Mol. Cell 25
  
  Pages: 751-764
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystallization and preliminary X-ray crystallographic study of alanyl-tRNA synthetase from the archaeon Archaeoglobus fulgidus2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 3)
  
  Pages: 224-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] let-7microRNA-mediated mRNA deadenylation and translationla repression in a mammalian cell-free system2007
- Author(s)
  Wakiyama, M., Takimoto, K., Ohata, O., Yokoyama, S.
- Journal Title
  
  Genes Dev 21(15)
  
  Pages: 1857-1862
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes.2007
- Author(s)
  Ishii, R., Minagawa, A., Takaku, H., Takagi, M., Nashimoto, M., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 63(Pt 8)
  
  Pages: 637-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea : crystal structure of Sep-tRNA : Cys-tRNA synthase from Archaeoglobus fulgidus.2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biol 370(1)
  
  Pages: 128-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Site-specific functionalization of proteins by organopalladium reactions2007
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama, H., Sakamoto, K., Kigawa, T., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Yokoyama, S., Tachibana, K.
- Journal Title
  
  Chenbiochem 8(2)
  
  Pages: 232-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A snapshot of the 30S ribosomal subusomal subunit capturing mRNA via the Shine-Dalgarno interaction2007
- Author(s)
  Kaminishi, T., Wilson, D. N., Takemoto, C., Harms, J. M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S.
- Journal Title
  
  Structure 15(3)
  
  Pages: 289-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Analysis of the tole of Aurora B on the chromosomal targeting of condensin I2007
- Author(s)
  Takemoto, A., Murayama, A., Katano, M., Urano, T., Furukawa, K., Yokoyama, S., Yanagisawa, J., Hanaoka, F., Kimura, K.
- Journal Title
  
  Nucleic Acids Res 35(7)
  
  Pages: 2403-2412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction.2007
- Author(s)
  Kaminishi, T., Wilson, D.N., Takemoto, C., Harms, J.M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S.
- Journal Title
  
  Structure 15
  
  Pages: 289-297
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural aspects of RbfA action during small ribosomal subunit assembly.2007
- Author(s)
  Datta, P. P., Wilson, D. N., Kawazoe, M., Swami, N. K., Kaminishi, T., Sharma, M. R., Booth, T. M., Takemoto, C, Fucini, P., Yokoyama, S., Agrawal, R. K.
- Journal Title
  
  Mol Cell 28(3)
  
  Pages: 434-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.2007
- Author(s)
  Connell, S. R., Takemoto, C, Wilson, D. N., Wang, H., Murayama, K., Terada, T., Shirouzu, M., Rost, M., Schuler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Yokoyama, S., Spahn, C. M.
- Journal Title
  
  Mol Cell 25(5)
  
  Pages: 751-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structure of the AlaX-M trans-editing enzyme from Pyrococcus horikoshii.2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 63(Pt 3)
  
  Pages: 390-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis for interaction of the ribosome with the switch reginons of GTP-bound elongation factors2007
- Author(s)
  Connell, S. R., Takemoto, C., Wlison, D. N Wang, H., Murayama, K., Teraka, T., Shirouzu, M., Rost, M., Schuler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Yokoyama, S., Spahn, C. M.
- Journal Title
  
  Mol Cell 25(5)
  
  Pages: 751-764
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine.2007
- Author(s)
  Kuratani, M., Yoshikawa, Y., Bessho, Y, Higashijima, K., Ishii, T., Shibata, R., Takahashi, S., Yutani, K., Yokoyama, S.
- Journal Title
  
  Structure 15(12)
  
  Pages: 1642-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural aspects of RbfA action during small ribosomal subunit assembly2007
- Author(s)
  Datta, P. P., Wilson, D. N., Kawazoe, M., Swami, N, K., Kaminishi, T., Sharma, M. R., Booth, T. M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R. K.
- Journal Title
  
  Mol Cell 28(3)
  
  Pages: 434-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Stmctural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA.2007
- Author(s)
  Bessho, Y., Shibata, R., Sekine, S., Murayama, K., Higashijima, K., Hori-Takemoto, C, Shirouzu, M., Kuramitsu, S., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 104(20)
  
  Pages: 8293-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Site-specific functionalization of proteins by organopalladium reactions2007
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama, H., Sakamoto, K., Kigawa, T., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Yokoyama, S., Tachibana, K.
- Journal Title
  
  Chembiochem 8
  
  Pages: 232-238
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis2007
- Author(s)
  Goto-Ito, S., Ishii, R, Ito, T., Shibata, R, Fusatomi, E., Sekine, S. I., Bessho, Y., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 63(Pt 10)
  
  Pages: 1059-1068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.2007
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat. Struct. Mol. Biol. 14
  
  Pages: 272-279
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase.2006
- Author(s)
  Sasaki, H.M., Sekine, S., Sengoku, T., Fukunaga, R., Hattori, M., Utsunomiya, Y., Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 103
  
  Pages: 14744-14749
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei2006
- Author(s)
  Yanagisawa, T., Ishii, R., Fukunaga, R, Nureki, O., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 62(Pt 10)
  
  Pages: 1031-1033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei.2006
- Author(s)
  Yanagisawa, T., Ishii, R., Fukunaga, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 62(Pt 10)
  
  Pages: 1031-3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase.2006
- Author(s)
  Sekine, S., Shichiri, M., Bernier, S., Chenevert, R., Lapointe, J., Yokoyama, S.
- Journal Title
  
  Structure 14(12)
  
  Pages: 1791-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA2006
- Author(s)
  Shigi, N., Suzuki, T., Terada, T., Shirouzu, M., Yokoyama, S., Watanabe, K
- Journal Title
  
  J Biol Chem 281(4)
  
  Pages: 2104-2113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] regioselective carbon-carbon bond formation in proteins with palladium catalysis; new protein chemistry by organometallic chemistry2006
- Author(s)
  Kodama, K., Fukuzawa, S., Nakayama, H., Kigawa, T., Sakamoto, K., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Tachibana, K., Yokoyama, S.
- Journal Title
  
  Chembiochem 7(1)
  
  Pages: 134-139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa2006
- Author(s)
  Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S., Yokoyama, S.
- Journal Title
  
  Cell 125(2)
  
  Pages: 287-300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation2006
- Author(s)
  Suetsugu, S., Murayama, K, Sakamoto, A., Hanawa-Suetsugu, K., Seto, A., Oikawa, T., Mishima, C., Shirouzu, M., Takenawa, T., Yokoyama, S.
- Journal Title
  
  J Biol Chem 281(46)
  
  Pages: 35347-35358
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase.2006
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J. Mol. Biol. 359
  
  Pages: 901-912
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystal structures of tyrosyl-tRNA synthetases from Archaea.2006
- Author(s)
  Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Murayama, K., Chen, L., Liu, Z. J., Wang, B. C., Kuroishi, C., Kuramitsu, S., Terada, T., Bessho, Y., Shirouzu, M., Sekine, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 355(3)
  
  Pages: 395-408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing2006
- Author(s)
  Daisuke Kiga, Shigeyuki Yokoyama, Masami Hagiya
- Journal Title
  
  BioSystems Vol.83, No.1
  
  Pages: 18-25
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Structural basis of CoA recognition by the Pyrococcus single-domain CoA-binding proteins2006
- Author(s)
  Hiyama, T. B., Zhao, M., Kitago, Y., Yao, M., Sekine, S., Terada, T., Kuroishi, C., Liu, Z. J., Rose, J. P., Kuramitsu, S., Shirouzu, M., Watanabe, N., Yokoyama, S., Tanaka, I., Wang, B. C.
- Journal Title
  
  J Struct Funct Genomics 7(3-4)
  
  Pages: 119-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase2006
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biol 359(4)
  
  Pages: 901-912
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural bases of transfer RNA-dependent amino-acid recognition and activation by glutamyl-tRNA synthetase.2006
- Author(s)
  Sekine, S., Shichiri, M., Bernier, S., Chenvert, R., Lapointe, J., Yokoyama, S.
- Journal Title
  
  Structure 14(12)
  
  Pages: 1791-1799
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Temperature-dependent biosynthesis of Thermus thermophilus tRNA2006
- Author(s)
  N.Shigi, T.Suzuki, T.Terada, M.Shirouzu, S.Yokoyama, K.Watanabe
- Journal Title
  
  J.Biol.Chem. 281
  
  Pages: 2104-2113
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystal structure of the single-domain rhodanese homologue TTHA0613 from Thermus thermophilus HB82006
- Author(s)
  Hattori, M., Mizohata, E., Tatsuguchi, A., Shibata, R, Kishishita, S., Murayama, K., Terada, T., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proteins 64(1)
  
  Pages: 284-287
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structures of tyrosyl-tRNA synthetases from Archaea2006
- Author(s)
  Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Murayama, K., Chen, L., Liu, ZJ., Wang, BC., Kuroishi, C., Kuramitsu, S., Terada, T., Bessho, Y., Shirouzu, M., Sekine, SI., Yokoyama, S.
- Journal Title
  
  J.Mol.Biol. 355
  
  Pages: 395-408
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis of the water-assisted asparagine recognition by asparaginyl-tRNA synthetase.2006
- Author(s)
  Iwasaki, W., Sekine, S., Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J Mol Biol 360(2)
  
  Pages: 329-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] An unnatural hydrophobic base pair system : site-specific incopration of nucleotide analogs into DNA and RNA2006
- Author(s)
  Hirao, I., Kimoto, M., Mitsui, T., Fujiwara, T., Kawai, R., Sato, A., Harada, Y., Yokoyama, S.
- Journal Title
  
  Nat Methods 3(9)
  
  Pages: 729-735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe2006
- Author(s)
  Kodama, K., Fukuzawa, S., Sakamoto, K., Nakayama, H., Kigawa, T., Yabuki, T., Matsuda, N., Shirouzu, M., Takio, K., Tachibana, K., Yokoyama, S.
- Journal Title
  
  Chembiochem 7(10)
  
  Pages: 1577-1581
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for RNA unwinding by the DEADbox protein Drosophila Vasa.2006
- Author(s)
  Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S., Yokoyama, S.
- Journal Title
  
  Cell 125(2)
  
  Pages: 287-300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP.2006
- Author(s)
  Kuwasako, K., He, F., Inoue, M., Tanaka, A., Sugano, S., Guntert, P., Muto, Y., Yokoyama, S.
- Journal Title
  
  Structure 14
  
  Pages: 1677-1689
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase.2006
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biol 359(4)
  
  Pages: 901-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.2006
- Author(s)
  Dong, X., Bessho, Y., Shibata, R., Nishimoto, M., Shirouzu, M., Kuramitsu, S., Yokoyama, S.
- Journal Title
  
  RNA Biology 3
  
  Pages: 115-121
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis of the water-assisted asparagine recognition by asparaginyl-tRNA synthetase.2006
- Author(s)
  Iwasaki, W., Sekine, S., Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J. Mol. Biol. 360
  
  Pages: 329-342
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Negative regulation of condensin I by CK2-mediated phosphorylation2006
- Author(s)
  Takemoto, A., Kimura, K., Yanagisawa, J., Yokoyama, S., Hanaoka, F.
- Journal Title
  
  EMBO J 25(22)
  
  Pages: 5339-5348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A New Protein Engineering Approach Combining Chemistry and Biology, Part I; Site-Specific Incorporation of 4-Iodo-L-phenylalanine in vitro by Using Misacylated Suppressor tRNA (Phe)2006
- Author(s)
  Kodama K, Fukuzawa S, Sakamoto K, Nakayama H, Kigawa T, Yabuki T, Matsuda N, Shirouzu M, Takio K, Tachibana K, Yokoyama S
- Journal Title
  
  Chembiochem 7
  
  Pages: 1577-1581
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing2006
- Author(s)
  Komiya K, Sakamoto K, Kameda A, Yamamoto M, Ohuchi A, Kiga D, Yokoyama S, Hagiya M
- Journal Title
  
  BioSystems Vol.83, No.1
  
  Pages: 18-25
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase2006
- Author(s)
  Sasaki, H. M., Sekine, S., Sengoku, T., Fukunaga, R., Hattori, M., Utsunomiya, Y, Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 103(40)
  
  Pages: 14744-14749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Translation of 'rare' Codons in a Cell-free Protein Synthesis System from Escherichia coli2006
- Author(s)
  Chumpolkulwong N, Sakamoto K, Hayashi A, Iraha F, Shinya N, Matsuda N, Kiga D, Urushibata A, Shirouzu M, Oki K, Kigawa T, Yokoyama S
- Journal Title
  
  J Struct Funct Genomics 7
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] The crystal structure of mouse Nup35 reveals atypical RNP motifs an novel homodimerization of the RRM domain.2006
- Author(s)
  Handa, N., Kukimoto, M., Akasaka, R., Kishishita, S., Murayama, K., Terada, T., Inoue, M., Kigawa, T., Kose, S., Imamoto, N., Tanaka, A., Hayashizaki, Y., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J. Mol. Biol. 363
  
  Pages: 114-124
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystal structures of tyrosyl-tRNA synthetases from Archaea2006
- Author(s)
  Kuratani, M., Sakai, H., Takahashi, M., Yanagisawa, T., Kobayashi, T., Murayama, K., Chen, L., Liu, Z. J., Wang, B. C., Kuroishi, C., Kuramitsu, S., Terada, T., Bessho, Y., Shirouzu, M., Sekine, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 355(3)
  
  Pages: 395-408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.2006
- Author(s)
  Schluenzen, F., Takemoto, C., Wilson, D.N., Kaminishi, T., Harms, J., Hanawa-Suetsugu, K., Szaflarski, W., Kawazoe, M., Shirouzu, M., Nierhaus, H.K., Yokoyama, S., Fucini, P.
- Journal Title
  
  Nat. Struct. Mol. Biol. 13
  
  Pages: 871-878
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA.2006
- Author(s)
  N.Shigi, T.Suzuki, T.Terada, M.Shirouzu, S.Yokoyama, K.Watanabe.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 2104-2113
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Cation-π interaction in triterpene biosynthesis revealed by incorporating unnatural amino acids into the catalytic site of a squalene cyclase2006
- Author(s)
  Noriko Morikubo, Yoriyuki Fukuda, Kazumasa Ohtake, Naoko, Shinya, Daisuke Kiga, Kensaku Sakamoto, Miwako Asanuma, Hiroshi Hirota, Shigeyuki Yokoyama, Tsutomu Hoshino
- Journal Title
  
  J. Am. Chem. Soc 128
  
  Pages: 13184-13194
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase2006
- Author(s)
  Sekine, S., Shichiri, M., Bernier, S., Chenevert, R., Lapointe, J., Yokoyama, S.
- Journal Title
  
  Structure 14(12)
  
  Pages: 1791-1799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of the water-assisted asparagine recognition by asparaginyl-tRNA synthetase2006
- Author(s)
  Iwasaki, W, Sekine, S., Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J Mot Biol 360(2)
  
  Pages: 329-342
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase.2006
- Author(s)
  Sasaki, H. M., Sekine, S., Sengoku, T., Fukunaga, R., Hattori, M., Utsunomiya, Y., Kuroishi, C., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 103(40)
  
  Pages: 14744-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation.2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biol 346(1)
  
  Pages: 57-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.2005
- Author(s)
  Watanabe, K., Nureki, O., Fukai, S., Ishii, R., Okamoto, H., Yokoyama, S., Endo, Y., Hori, H.
- Journal Title
  
  J Biol Chem 280(11)
  
  Pages: 10368-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the hypothetical protein TTHA1013 from Thermus thermophilus HB82005
- Author(s)
  Hattori, M., Mizohata, E., Manzoku, M., Bessho, Y., Murayama, K., Terada, T., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proteins 61(4)
  
  Pages: 1117-1120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B protein2005
- Author(s)
  Kurimoto, K., Muto, Y., Obayashi, N., Terada, T., Shirouzu, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Kigawa, T., Okumura, H., Tanaka, A., Shibata, N., Kashikawa, M., Agata, K., Yokoyama, S.
- Journal Title
  
  J Struct Biol 150(1)
  
  Pages: 58-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B (DjVLGB) protein2005
- Author(s)
  Kurimoto, K., Muto, Y., Obayashi, N., Terada, T., Shirouzu, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Kigawa, T., Okumura, H., Tanaka, A., Shibata, N., Kashikawa, M., Kiyokazu, A., Yokoyama, S.
- Journal Title
  
  J.Struct.Biol. 150
  
  Pages: 58-68
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Mol Biot 346(1)
  
  Pages: 57-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion2005
- Author(s)
  Kobayashi, T., Sakamoto, K., Takimura, T., Sekine, R., Kelly, V. P., Kamata, K., Nishimura, S., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 102(5)
  
  Pages: 1366-1371
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation2005
- Author(s)
  Tukalo, M., Yaremchuk, A., Fukunaga, R., Yokoyama, S., Cusack, S.
- Journal Title
  
  Nat.Struct.Mol.Biol. 12
  
  Pages: 923-930
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] The Aminoacyl-tRNA Synthetases : Chapter7 & 82005
- Author(s)
  Yokoyama, S.
- Journal Title
  
  The Aminoacyl-tRNA Synthetase Landes Bioscience
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Roles of conserved amino acid sequence motifs in the SpoU (TrmH0 RNA methyltransferase family2005
- Author(s)
  Watanabe, K., Nureki, O., Fukai, S., Ishiii, Okamoto, H., Yokoyama, S., Endo, Y., Hori, H.
- Journal Title
  
  J Biol Chem 280(110
  
  Pages: 10368-10377
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase.2005
- Author(s)
  Kobayashi, T., Takimura, T., Sekine, R., Kelly, V. P., Kamata, K., Sakamoto, K., Nishimura, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 346(1)
  
  Pages: 105-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the RNA 2'-phosphotransferase from Aeropyrum pemix K12005
- Author(s)
  Kato-Murayama, M., Bessho, Y., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  J.Mol.Biol. 348
  
  Pages: 295-305
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structure of a putative trans-editing enzyme for prolyl-tRNA synthetase from Aeropyrum pernix K1 at 1.7 A resolution2005
- Author(s)
  Murayama., K, Kato-Murayama, M., Katsura, K, Uchikubo-Kamo, T., Yamaguchi-Hirafuji, M., Kawazoe, M., Akasaka, R., Hanawa-Suetsugu, K., Hori-Takemoto, C., Terada, T., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 61(Pt 1)
  
  Pages: 26-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the tRNA 3' processing endoribonuclease tRNase Z from Thermotoga maritima2005
- Author(s)
  Ishii, R., Minagawa, A., Takaku, H., Takagi, M., Nashimoto, M., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(14)
  
  Pages: 14138-14144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii.2005
- Author(s)
  Fukunaga, R., Ishitani, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 61(Pt 1)
  
  Pages: 30-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion.2005
- Author(s)
  Kobayashi, T., Sakamoto, K., Takimura, T., Sekine, R., Kelly, V. P., Kamata, K., Nishimura, S., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 102(5)
  
  Pages: 1366-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation2005
- Author(s)
  Tukalo, M., Yaremchuk, A., Fukunaga, R., Yokoyama, S., Cusack, S.
- Journal Title
  
  Nat Struct Mol Biol 12(10)
  
  Pages: 923-930
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus2005
- Author(s)
  Kuratani, M., Ishii, R., Bessho, Y., Fukunaga, R., Sengoku, T., Shirouzu, M., Sekine, S., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(16)
  
  Pages: 16002-16008
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat Struct Mot Biol 12(10)
  
  Pages: 915-922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Human centromere protein B induces translational positioning of nucleosomes on alpha-satellite sequences2005
- Author(s)
  Tanaka, Y., Tachiwana, H., Yoda, K., Masumoto, H., Okazaki, T., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(50)
  
  Pages: 41609-41618
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion2005
- Author(s)
  Kobayashi T, Sakamoto K, Takimura T, Sekine R, Vincent K, Kamata K, Nishimura S, Yokoyama S.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102
  
  Pages: 1336-1371
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid2005
- Author(s)
  Hino, N., Okazaki, Y., Kobayashi, T., Hayashi, A., Sakamoto, K., Yokoyama, S.
- Journal Title
  
  Nat Methods 2(3)
  
  Pages: 201-206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structure of a putative trans-editing enzyme for prolyl-tRNA synthetase from Aeropyrum pernix K1 at 1.7 A resolution.2005
- Author(s)
  Murayama, K., Kato-Murayama, M., Katsura, K., Uchikubo-Kamo, T., Yamaguchi-Hirafuji, M., Kawazoe, M., Akasaka, R., Hanawa-Suetsugu, K., Hori-Takemoto, C, Terada, T., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 61(Pt 1)
  
  Pages: 26-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B protein.2005
- Author(s)
  Kurimoto, K., Muto, Y., Obayashi, N., Terada, T., Shirouzu, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Kigawa, T., Okumura, H., Tanaka, A., Shibata, N., Kashikawa, M., Agata, K., Yokoyama, S.
- Journal Title
  
  J Struct Biol 150(1)
  
  Pages: 58-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly.2005
- Author(s)
  Sharma, M. R., Barat, C., Wilson, D. N., Booth, T. M., Kawazoe, M., Hori-Takemoto, C., Shirouzu, M., Yokoyama, S., Fucini, P., Agrawal, R. K.
- Journal Title
  
  Mol Cell 18(3)
  
  Pages: 319-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] "CpG methylation of the CENP-B box reduces human CENP-B binding2005
- Author(s)
  Tanaka, Y., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  FEBS J 272(1)
  
  Pages: 282-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid2005
- Author(s)
  Hino N., Okazaki Y., Kobayashi T., Hayashi A., Sakamoto K., Yokoyama S.
- Journal Title
  
  Nature Methods 2
  
  Pages: 201-206
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation.2005
- Author(s)
  Tukalo, M., Yaremchuk, A., Fukunaga, R., Yokoyama, S., Cusack, S.
- Journal Title
  
  Nat Struct Mol Biol 12(10)
  
  Pages: 923-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii2005
- Author(s)
  Fukunaga, R., Ishitani, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun 61(Pt 1)
  
  Pages: 30-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 29937-29945
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus.2005
- Author(s)
  Kuratani, M., Ishii, R., Bessho, Y., Fukunaga, R., Sengoku, T., Shirouzu, M., Sekine, S., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(16)
  
  Pages: 16002-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus2005
- Author(s)
  Kuratani, M., Ishii, R., Bessho, Y., Fukunaga, R., Sengoku, T., Shirouzu, M., Sekine, SI., Yokoyama, S.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 16002-16008
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase2005
- Author(s)
  Kobayashi T, Takimura T, Sekine R, Vincent K, Kamata K, Sakamoto K, Nishimura S, Yokoyama S.
- Journal Title
  
  J Mol.Biol. 346
  
  Pages: 105-117
- Data Source
  KAKENHI-PROJECT-14085202
[Journal Article] Crystal structure of the tRNA 3' processing endoribonuclease tRNase Z from Thermotoga maritima.2005
- Author(s)
  Ishii, R., Minagawa, A., Takaku, H., Takagi, M., Nashimoto, M., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(14)
  
  Pages: 14138-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(33)
  
  Pages: 29937-429945
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the tRNA 3' processing endoribonuclease tRNase Z from Thermotoga maritime2005
- Author(s)
  Ishii, R., Minagawa, A., Takaku, H., Takagi, M., Nashimoto, M., Yokoyama, S.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 14138-14144
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition.2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat Struct Mol Biol 12(10)
  
  Pages: 915-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Role of the N-terminal domain of the human DMC1 protein in octamer formation and DNA binding2005
- Author(s)
  Kinebuchi, T., Kagawa, W., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(31)
  
  Pages: 28382-28387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat.Struct.Mol.Biol. 12
  
  Pages: 915-922
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Interaction analysis between tmRNA and SmpB from Thermus Thermophilus.2005
- Author(s)
  Nameki, N., Someya, T., Okano, S., Suemasa, R., Kimoto, M., Hanawa-Suetsugu, K., Terada, T., Shirouzu, M., Hirao, I., Takaku, H., Himeno, H., Muto, A., Kuramitsu, S., Yokoyama, S., Kawai, G.
- Journal Title
  
  J. Biochem. 138
  
  Pages: 729-739
- NAID
  10017348907
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain.2005
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  J Biol Chem 280(33)
  
  Pages: 29937-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase2005
- Author(s)
  Kobayashi, T., Takimura, T., Sekine, R., Kelly, V. P., Kamata, K., Sakamoto, K., Nishimura, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 346(1)
  
  Pages: 105-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly2005
- Author(s)
  Sharma, M. R., Barat, C., Wilson, D. N., Booth, T. M., Kawazoe, M., Hori-Takemoto, C., Shirouzu, M., Yokoyama, S., Fucini, P., Agrawal, R., K.
- Journal Title
  
  Mol Cell 18(3)
  
  Pages: 319-329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Interaction of Era with the 30S ribosomal subunit : Implications for 30S subunit assembly2005
- Author(s)
  Sharma, M.R., Barat, C., Wilson, D.N., Booth, T.M., Kawazoe, M., Hori-Takemoto, C., Shirouzu, M., Yokoyama, S., Fucini, P., Agrawal, R.K.
- Journal Title
  
  Mol.Cell 18
  
  Pages: 319-329
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme.2004
- Author(s)
  Nureki, O., Watanabe, K., Fukai, S., Ishii, R., Endo, Y., Hori, H., Yokoyama, S.
- Journal Title
  
  Structure 12(4)
  
  Pages: 593-602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystallization and preliminaty X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue2004
- Author(s)
  Sengoku, T., Nureki, O., Dohmae, N., nakamura, A., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt 2)
  
  Pages: 320-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Cell cycle-dependent phosphorylation, nuclear localization, and activation of human condensin2004
- Author(s)
  Takemoto, A., Kimura, K., Yokoyama, S., Hanaoka, F.
- Journal Title
  
  J Biol Chem 279(6)
  
  Pages: 4551-4559
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary X-ray crystallographic study of leucyl-tRNA synthetase from the archaceon Pyrococcus horikoshii2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Nat Struct Mol Biol 11(2)
  
  Pages: 149-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Site-specific incorporation of a photo-crosslinking component into RNA by T7 transcription mediated by unnatural base pairs.2004
- Author(s)
  Kimoto, M., Endo, M., Mitsui, T., Okuni, T., Hirao, I., Yokoyama, S.
- Journal Title
  
  Chem Biol 11(1)
  
  Pages: 47-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Regulation through the secondary channel-structural framework for ppGpp-DksA synergism during transcription.2004
- Author(s)
  Perederina, A., Svetlov, V., Vassylyeva, M. N., Tahirov, T. H., Yokoyama, S., Artsimovitch, I., Vassylyev, D. G.
- Journal Title
  
  Cell 118(3)
  
  Pages: 297-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] tRNA recognition by glutamyl-tRNA reductase2004
- Author(s)
  Randau, L., Schauer, S., Ambrogelly, A., Salazar, J. C., Moser, J., Aekine, S., Yokoyama, S., Soll, D., Jahn, D.
- Journal Title
  
  J Biol Chem 279(33)
  
  Pages: 34931-34937
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary Xray crystallographic study of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii.2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt10)
  
  Pages: 1916-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural basis for substrate selection by t7 RNA polymerase.2004
- Author(s)
  Temiakov, D., Patlan, V., Anikin, M., McAllister, W. T., Yokoyama, S., Vassylyev, D. G.
- Journal Title
  
  Cell 116(3)
  
  Pages: 381-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of elongation factor P from Thermus thermophilus HB8.2004
- Author(s)
  Hanawa-Suetsugu, K., Sekine, S., Sakai, H., Hori-Takemoto, C., Terada, T., Unzai, S., Tame, J. R., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 101(26)
  
  Pages: 9595-600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125(MUC16)2004
- Author(s)
  Maeda, T., Inoue, M., Koshiba, S., Yabuki, T., Aoki, M., Nunokawa, E., Seki, EMatsuda, T., Motoda, Y., Kobayashi, A., Hiroyasu, F., Shirouzu, M., Terada, T., Hayami, N., Ishizuka, Y., Shinya, N., Tatsuguchi, A., Yoshida, M., Hirota, H., Matsuo, Y., Tani, K., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T., Yokoyama, S.
- Journal Title
  
  J Biol Chem 279(13)
  
  Pages: 13174-13182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription factor DksA from Escherichia coli.2004
- Author(s)
  Vassylyeva, M. N., Perederina, A. A., Svetlov, V., Yokoyama, S., Artsimovitch, I., Vassylyev, D. G.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt9)
  
  Pages: 1611-3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] The Escherichia coli argU10(Ts)phenotype is caused by a reduction in the cellular level of the argU tRNA for the rare codons AGA and AGG2004
- Author(s)
  Sakamoto, K., Ishimaru, S., Kobayashi, T., Walker, J. R., Yokoyama, S.
- Journal Title
  
  J Bacteriol 186(17)
  
  Pages: 5899-5905
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for transcription regulation by alarmone ppGpp.2004
- Author(s)
  Artsimovitch, I., Patlan, V., Sekine, S., Vassylyeva, M. N., Hosaka, T., Ochi, K., Yokoyama, S., Vassylyev, D. G.
- Journal Title
  
  Cell 117(3)
  
  Pages: 299-310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Expression and purification of recombinant human histones2004
- Author(s)
  Tanaka, Y., Tawaramoto-Sasanuma, M., Kawaguchi, S., Ohta, T., Yoda, K., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  Methods 33(1)
  
  Pages: 3-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmcl2004
- Author(s)
  Kinebuchi, T., Kagawa, W., Enomoto, R., Tanaka, K., Miyagawa, K., Shibata, T., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  Mol Cell 14(3)
  
  Pages: 363-374
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine2004
- Author(s)
  Fukunaga, R., Fukai, S., Ishitani, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  J Biol Chem 279(9)
  
  Pages: 8396-8402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine.2004
- Author(s)
  Fukunaga, R., Fukai, S., Ishitani, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  J Biol Chem 279(9)
  
  Pages: 8396-402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Solution structure of a BolA-like protein from Mus musculus.2004
- Author(s)
  Kasai, T., Inoue, M., Koshiba, S., Yabuki, T., Aoki, M., Nunokawa, E., Seki, E., Matsuda, T., Matsuda, N., Tomo, Y., Shirouzu, M., Terada, T., Obayashi, N., Hamana, H., Shinya, N., Tatsuguchi, A., Yasuda, S., Yoshida, M., Hirota, H., Matsuo, Y., Tani, K., Suzuki, H., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T., Yokoyama, S.
- Journal Title
  
  Protein Sci 13(2)
  
  Pages: 545-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of elongation factor P from Thermus thermophilus HB82004
- Author(s)
  Hanawa-Suetsugu, K., Sekine, S., Sakai, H., Hori-Takemoto, C., Terada, T., Unzai, S., Tame, J. R., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 101(26)
  
  Pages: 9595-9600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Regulation through the secondary channel-structural framework for ppGpp-DksA synergism during transcription2004
- Author(s)
  Perederina, A., Svetlov, V., Vassylyeva, M. N., Tahirov, T. H., Yokoyama, S., Artsimovitch, I., Vassylyev, D. G.
- Journal Title
  
  Cell 118(3)
  
  Pages: 297-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Solution structure of a BolA-like protein from Musmusculus2004
- Author(s)
  Kasai, T., Inoue, M., Koshiba, S., Yabuki, T., Aoki, M., Nunokawa, E., Seki, E., Matsuda, T., Matsuda, N., Tomo, Y., Shirouzu, M., Terada, T., Obayashi, N., Hamana, H., Shinya, N., Tatsuguchi, A., Yasuda, S., Yoshida, M., Hirota, H., Matsuo, Y., Tani, k., Suzuki, H., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Kigawa, T., Yokoyama, S
- Journal Title
  
  Protein Sci 13(2)
  
  Pages: 545-548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Site-specific incorporation of a photo-crosslinking component into RNA by T7 transcription mediated by unnatural base pairs2004
- Author(s)
  Kimoto, M., Endo, M., Mitsui, T., Okuni, T., Hirao, I., Yokoyama, S.
- Journal Title
  
  Chem Biol 11(1)
  
  Pages: 47-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase2004
- Author(s)
  Kise, Y., lee, S. E., park, S. G., Fukai, S., Sengoku, T., Ishii, R., Yokoyama, S., Kim, S., Nureki, O.
- Journal Title
  
  Nat Struct Mol Biol 11(2)
  
  Pages: 149-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] In vitro selection of RNA aptamers that bind to colicin E3 and structurally tesemble the decoding site of 16S ribosomal RNA2004
- Author(s)
  Hirao, I., Harada, Y., Nojima, T., Osawa, Y., Masaki, H., Yokoyama, S.
- Journal Title
  
  Biochemistry 43(11)
  
  Pages: 3214-3221
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for substrate selection by t7RNA polymerase2004
- Author(s)
  Temiakov, D., Patlan, V., Anikin, M., McAllister, W. T., Yokoyama, S., Vassylyev, D. G.
- Journal Title
  
  Cell 116(3)
  
  Pages: 381-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription factor DksA from Escherichia coli2004
- Author(s)
  Vassylyeva, M. N., Perederina, A. A., Svetlov, V., Yokoyama, S., Artsimovitch, I., Vassylyev, D. G.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt 9)
  
  Pages: 1611-1613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for transcription regulation by alarmone ppGpp2004
- Author(s)
  Artsimovitch, I., Patlan, V., Sekine, S., Vassylyeva, M. N., Hosaka, T., Ochi, K., Yokoyama, S., Vassylyev, D. G.
- Journal Title
  
  Cell 117(3)
  
  Pages: 299-310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary X-ray crystallographic study of the editing domain of Thermus thermophilus isoleucyl-tRNA synthetase complexed with pre- and post-transfer editing-substrate analogues.2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt 10)
  
  Pages: 1900-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Deep knte of tRNA modification enzyme2004
- Author(s)
  Nureki, O., Watanabe, K, Fukai, S., Ishii, R, Endo, Y, Hori, H., Yokoyama, S.
- Journal Title
  
  Structure 12(4)
  
  Pages: 593-602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] In vitro selection of RNA aptamers that bind to colicin E3 and structurally resemble the decoding site of 16S ribosomal RNA.2004
- Author(s)
  Hirao, I., Harada, Y., Nojima, T., Osawa, Y., Masaki, H., Yokoyama, S.
- Journal Title
  
  Biochemistry 43(11)
  
  Pages: 3214-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] tRNA recognition by glutamyl-tRNA reductase.2004
- Author(s)
  Randau, L., Schauer, S., Ambrogelly, A., Salazar, J. C, Moser, J., Sekine, S., Yokoyama, S., Soll, D., Jahn, D.
- Journal Title
  
  J Biol Chem 279(33)
  
  Pages: 34931-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue.2004
- Author(s)
  Sengoku, T., Nureki, O., Dohmae, N., Nakamura, A., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt2)
  
  Pages: 320-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structural and biochemical analyses of hemimethylated DNA binding by the SegA protein2004
- Author(s)
  Fujikawa, N., Kurumizaka, H., Nureki, O., Tanaka, Y., Yamazoe, M., Hiraga, S., Yokoyama, S.
- Journal Title
  
  Nucleic Acids Res 32(1)
  
  Pages: 82-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystallization and preliminary X-ray crystallographic study of leucy-tRNA synthetase from the archaeon Pyrococcus horikoshii2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 60(Pt 10)
  
  Pages: 1900-1902
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the 2'-5' RNA ligase from Thermus thermophilus HB8.2003
- Author(s)
  Kato, M., Shirouzu, M., Terada, T., Yamaguchi, H., Murayama, K., Sakai, H., Kuramitsu, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 329(5)
  
  Pages: 903-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the human centromere protein B(CENP-B) dimerization domain at 1.65-A resolution2003
- Author(s)
  Tawaramoto, M. S., Park, S. Y., Tanaka, Nureki, O., Kurumizaka, H., Yokoyama, S.
- Journal Title
  
  J Biol Chem 278(51)
  
  Pages: 51454-51461
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Reconstitution of Src-dependent phospholipase Cgamma phosphorylation and transient calcium release by using membrane rafts and cell-free extracts from Xenpus eggs2003
- Author(s)
  Sato, K., Tokmakov, A. A., He, C. L., Kurokawa, M., Iwasaki, T., Shirouzu, M., Fissore, R. A., Yokoyama, S., Fukami, Y.
- Journal Title
  
  J Biol Chem 278(40)
  
  Pages: 38413-38420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase.2003
- Author(s)
  Fukai, S., Nureki, O., Sekine, S., Shimada, A., Vassylyev, D. G., Yokoyama, S.
- Journal Title
  
  RNA 9(1)
  
  Pages: 100-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the 2'-5' RNA ligase from Thermus thermopilus HB82003
- Author(s)
  Kato, M., Shirouzu, M., Terada, T., Yamaguchi, H., Murayama, K., Sakai, H., Kuramitsu, S., Yokoyama, S.
- Journal Title
  
  J Mol Biol 329(5)
  
  Pages: 903-911
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Roles of 5-substiutents of tRNA wobble uridines in the recognition of purine-ending codons2003
- Author(s)
  Takai, K., Yokoyama, S.
- Journal Title
  
  Nucleic Acids Res 31(22)
  
  Pages: 6383-6391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis of replication origin recognition by the DnaA protein2003
- Author(s)
  Fujikawa, N., Kurumizaka, H., Nureki, O., Terada, T., Shirouzu, M., Katayama, T., Yokoyama, S.
- Journal Title
  
  Nucleic Acids Ees 31(8)
  
  Pages: 2077-2086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus.2003
- Author(s)
  Ishii, R., Nureki, 0., Yokoyama, S.
- Journal Title
  
  J Biol Chem 278(34)
  
  Pages: 32397-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors2003
- Author(s)
  Burgess, A. W., Cho, H. S., Eigenbrot, C., Ferguson, K. M., Garrett, T. P., Leahy, D. J., Lemmon, M. A., Sliwkowski, M. X., Ward, C. W., Yokoyama, S.
- Journal Title
  
  Mol Cell 12(3)
  
  Pages: 541-542
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion.2003
- Author(s)
  Kobayashi, T., Nureki, 0., Ishitani, R., Yaremchuk, A., Tukalo, M., Cusack, S., Sakamoto, K., Yokoyama, S.
- Journal Title
  
  Nat Struct Biol 10(6)
  
  Pages: 425-32
- NAID
  110001158009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of ribosomal protein L11 methyltransferase from Thermus thermophilus HB8.2003
- Author(s)
  Kaminishi, T., Sakai, H., Takemoto-Hori, C, Terada, T., Nakagawa, N., Maoka, N., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 59(Pt 5)
  
  Pages: 930-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Alternative tertiary structure of tRNA for recognition by a posttranscriptional modification enzyme.2003
- Author(s)
  Ishitani, R., Nureki, O., Nameki, N., Okada, N., Nishimura, S., Yokoyama, S.
- Journal Title
  
  Cell 113(3)
  
  Pages: 383-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure2003
- Author(s)
  Okabe, M., Tomita, K., Ishitani, R., Ishii, R., Takeuchi, N., Arisaka, F., Nureki, O., Yokoyama, S.
- Journal Title
  
  EMBO J 22(21)
  
  Pages: 5981-5927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure.2003
- Author(s)
  Okabe, M., Tomita, K., Ishitani, R., Ishii, R., Takeuchi, N., Arisaka, F., Nureki, O., Yokoyama, S.
- Journal Title
  
  EMBO J 22(21)
  
  Pages: 5918-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystal structure of the tRNA processing enzyme RNase PH from Aquifex aeolicus2003
- Author(s)
  Ishii, R., Nureki, O., Yokoyama, S.
- Journal Title
  
  J Biol Chem 278(34)
  
  Pages: 32397-32404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex : implications for the mechanism of primase-UTP complex : implications for the mechanism of primer synthesis2003
- Author(s)
  Ito, N., Nureki, O., Shirouzu, M., Yokoyama, S., Hanaoka, F.
- Journal Title
  
  Genes Cell 8(12)
  
  Pages: 913-923
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I and class II lysyl-tRNA synthetases2003
- Author(s)
  Polycarpo, C., Ambrogelly, A., Ruan, B., Tumbula-Hansen, D., Ataide, S. F., Ishitani, R., Yokoyama, S., Nureki, O., Ibba, M., Soll, D.
- Journal Title
  
  Mol Cell 12(2)
  
  Pages: 287-294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Activation of the pyrrolysine suppressor tRNA requires formation of a ternary complex with class I and class II lysyl-tRNA synthetases.2003
- Author(s)
  Polycarpo, C., Ambrogelly, A., Ruan, B., Tumbula-Hansen, D., Ataide, S. F., Ishitani, R., Yokoyama, S., Nureki, O., Ibba, M., Soil, D.
- Journal Title
  
  Mol Cell 12(2)
  
  Pages: 287-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding.2003
- Author(s)
  Sekine, S., Nureki, 0., Dubois, D. Y., Bernier, S., Chenevert, R., Lapointe, J., Vassylyev, D. G., Yokoyama, S.
- Journal Title
  
  EMBO J 22(3)
  
  Pages: 676-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Crystallization and preliminaty X-ray diffraction analysis of ribosomal protein L11 methyltransferase from Thermus thermophilus HB82003
- Author(s)
  Kaminishi, T., Sakai, H., Takemoto-Hori, C., Terada, T., Nakagawa, N., Maoka, N., Kuramitsu, S., Shirouzu, M., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 59(Pt 5)
  
  Pages: 930-932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Journal Article] Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus.2003
- Author(s)
  Someya, T., Nameki, N., Hosoi, H., Suzuki, S., Hatanaka, H., Fujii, M, Terada, T., Shirouzu, ML, Inoue, Y., Shibata, T., Kuramitsu, S., Yokoyama, S., Kawai, G.
- Journal Title
  
  FEBS lett. 535
  
  Pages: 94-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Purification, crystallization and initial crystallographic analysis of RNA polymerase holoenzyme from Thermus thermophilus.2002
- Author(s)
  Vassylyeva, M. N., Lee, J., Sekine, S. I., Laptenko, O., Kuramitsu, S., Shibata, T., Inoue, Y., Borukhov, S., Vassylyev, D. G., Yokoyama, S.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr 58(Pt9)
  
  Pages: 1497-500
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] An engineered Escherichia coli tyrosyl-tRNA synthetase for site-specific incorporation of an unnatural amino acid into proteins in eukaryotic translation and its application in a wheat germ cell-free system.2002
- Author(s)
  Kiga, D., Sakamoto, K., Kodama, K., Kigawa, T., Matsuda, T., Yabuki, T., Shirouzu, M., Harada, Y., Nakayama, H., Takio, K., Hasegawa, Y., Endo, Y., Hirao, I., Yokoyama, S.
- Journal Title
  
  Proc Natl Acad Sci U S A 99(15)
  
  Pages: 9715-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] Structure of a T7 RNA polymerase elongation complex at 2.9 A resolution.2002
- Author(s)
  Tahirov, T. H., Temiakov, D., Anikin, M., Patlan, V., McAllister, W. T., Vassylyev, D. G., Yokoyama, S.
- Journal Title
  
  Nature 420(6911)
  
  Pages: 43-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Journal Article] The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNAIle.
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Journal Title
  
  Biochemistry (In press)
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis for functional mimicry of long-variable-arm tRNA by tmRNA.
- Author(s)
  Bessho, Y., Shibata, R., Sekine, S., Murayama, K., Higashijima, K., Hori-Takemoto, C., Shirouzu, M., Kuramitsu S., Yokoyama, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. (In press)
- Data Source
  KAKENHI-PROJECT-13051101
[Journal Article] Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
- Author(s)
  Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S., Yokoyama, S.
- Journal Title
  
  Cell (in press)
- Data Source
  KAKENHI-PROJECT-13051101
[Patent] 変異体SepRS及びこれを用いるタンパク質への部位特異的ホスホセリン導入法2006
- Inventor(s)
  横山茂之福永流也関根俊一
- Industrial Property Rights Holder
  東京大学理化学研究所
- Filing Date
  2006-06-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Presentation] Structure and function of an HLA-DP5 peptide complex2018
- Author(s)
  Yokoyama Shigeyuki
- Organizer
  The 1st International Symposium on NEO-SELF
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06500
[Presentation] ネオ・セルフの立体構造解析2017
- Author(s)
  横山茂之
- Organizer
  新学術領域研究「ネオ・セルフの生成・機能・構造」第１回領域全体班会議
- Data Source
  KAKENHI-PLANNED-16H06500
[Presentation] The flanking region of cedar pollen peptide in complex with HLA-DP5 facilitates T-cell activation.2016
- Author(s)
  Kusano, S., Ueda, S., Hamana, H., Kishi, H., Muraguchi, A., Ohsawa, N., Wakiyama, M., Yoshikai, Y., Yamada, H., Yamamoto, K., Kukimoto-niino, M., Nishimura, Y., Shirouzu, M., Sasazuki, T. and Yokoyama, S.
- Organizer
  16th International Congress of Immunology (ICI2016)
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06500
[Presentation] Cls-lnteractlon of TCRs and antigen/MHC class 1 Complexes on CD8+ T cells causes their activation.2016
- Author(s)
  Kishi, H., Jin, A., Hamana, H., Shitaoka, K., Tajiri, K., Kobayashi, E., Kusano, S., Yokoyama, S., Ozawa, T., Nagai, T., Obata, T., Hatakeyama, S., Horii, M., Hu, Y., Zhang, F. and Muraguchi, A.
- Organizer
  16th International Congress of Immunology (ICI2016)
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06500
[Presentation] HLA-DP5によるスギ花粉抗原Cry j 1の特異的認識に対する構造的基盤2014
- Author(s)
  草野清輔、新野睦子、颯田葉子、大沢登、加茂友美、脇山素明、池田眞理子、寺田貴帆、山本健、西村泰治、白水美香子、笹月健彦、横山茂之
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PLANNED-22133004
[Presentation] Cedar pollen peptide・HLA-DP5 complex forms a homophilic assembly for T cell activation2014
- Author(s)
  草野清輔、横山茂之、笹月健彦
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10
- Invited
- Data Source
  KAKENHI-PLANNED-22133004
[Presentation] 大気圧プラズマによる水中脱色反応の研究2013
- Author(s)
  近藤崇博、鷹尾治樹、伊藤剛仁、伊藤拓宏、横山茂之
- Organizer
  2013 年春季第60回応用物理学関連連合講演会
- Place of Presentation
  神奈川工科大学
- Data Source
  KAKENHI-PROJECT-23651218
[Presentation] 大気圧プラズマによる水中脱色反応の研究2013
- Author(s)
  近藤崇博，鷹尾治樹，伊藤剛仁，伊藤拓宏，横山茂之
- Organizer
  2013年春季第60回応用物理学関連連合講演会
- Place of Presentation
  神奈川工科大学（神奈川県）
- Data Source
  KAKENHI-PROJECT-23651218
[Presentation] Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein2011
- Author(s)
  Yokoyama, S
- Organizer
  FASEB Summer Research Conferences Mechanism & Regulation of Procaryotic Transcription
- Place of Presentation
  Saxtons River, USA
- Data Source
  KAKENHI-PROJECT-20247008
[Presentation] Crystallographic Studies of Aminoacyl-tRNA Synthesis and tRNA Modification2010
- Author(s)
  Itoh, Y., Chiba, S., Naganuma, M., Goto-ito, S., Fukunaga, R., Kuratani, M., Bessho, Y., Ito, T., Sekine, SI., Yokoyama, S.
- Organizer
  23rd tRNA Workshop
- Place of Presentation
  Aveiro, Portugal
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PROJECT-20247008
[Presentation] Structural basis of transcription regulation revealed by the crystal structure of Thermus thermophilus RNA polymerase elongation complex bound with a transcriptional regulator Gfh1.2009
- Author(s)
  関根俊一、田上俊輔、Thirumananseri Kumarevel、横山茂之
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20247008
[Presentation] Crystal structure of an RNA polymerase translocation intermediate.2009
- Author(s)
  田上俊輔、関根俊一、Thirumananseri Kumarevel、横山茂之
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20247008
[Presentation] Structural biology and engineering of the transcription and translation systems2009
- Author(s)
  Yokoyama, S.
- Organizer
  International Symposium "Membranes and Modules"
- Place of Presentation
  Berlin, Germany
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20247008
[Presentation] RIKEN structural genomics/proteomics initiative2006
- Author(s)
  Yokoyama, S.
- Organizer
  International Conference on Aminoacyl-tRNA Synthetases : From the genetic Code to Human Disease & Medicine(AARS2006)
- Place of Presentation
  SanDiego, USA
- Year and Date
  2006-10-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] RIKEN structural genomics/proteomics initiative.2006
- Author(s)
  Yokoyama, S.
- Organizer
  International Conference on Aminoacyl-tRNA Synthetases : From the genetic Code to Human Disease & Medicine (AARS2006)
- Place of Presentation
  SanDiego, USA
- Year and Date
  2006-10-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] Structural proteomics of transcription and translation proteins2005
- Author(s)
  Yokoyama, S.
- Organizer
  30th FEBS Congress and 9th IUBMB Conference
- Place of Presentation
  Budapest, Hungary
- Year and Date
  2005-07-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Presentation] Structural proteomics of transcription and translation proteins.2005
- Author(s)
  Yokoyama, S.
- Organizer
  30th FEBS Congress and 9th IUBMB Conference
- Place of Presentation
  Budapest, Hungary
- Year and Date
  2005-07-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] Structural proteomics of transcription and translation proteins2005
- Author(s)
  Yokoyama, S.
- Organizer
  30th FEBS Congress and 9th IUBMB Conference
- Place of Presentation
  Budapest, Hungary
- Year and Date
  2005-07-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] Structural basis for the non-cognate amino acid editing by isoleucyl-tRNA syntehtase2004
- Author(s)
  Yokoyama, S.
- Organizer
  2004 International Conference on Aminoacyl-tRNA Synthetases : Ancient Molecules for Future Biology and Medicine {ARS2004)
- Place of Presentation
  Seoul, SouthKorea
- Year and Date
  2004-07-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] Structural basis for the non-cognate amino acid editing by isoleucyl-tRNA syntehtase.2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Organizer
  2004 International Conference on Aminoacyl-tRNA Synthetases : Ancient Molecules for Future Biology and Medicine(ARS2004)
- Place of Presentation
  Seoul, SouthKorea
- Year and Date
  2004-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035205
[Presentation] Structural basis for the non-cognate amino acid editing by isoleucyl-tRNA sntehtase2004
- Author(s)
  Fukunaga, R., Yokoyama, S.
- Organizer
  2004 International Conference on Aminoacyl-tRNA Synthetases : Ancient Molecules for Future Biology and Medicine (ARS2004)
- Place of Presentation
  Seoul, SouthKorea
- Year and Date
  2004-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15107002
[Presentation] Structural basis for the noncognate amino acid editing by isoleucyl-tRNA syntehtase2004
- Author(s)
  Yokoyama, S.
- Organizer
  2004 International Conference on Aminoacyl-tRNA Synt hetases: Ancient Molecules for Future Biology and Medicine(ARS2004)
- Place of Presentation
  Seoul, SouthKorea
- Year and Date
  2004-07-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15107002

1. WATANABE Kimitsuna (00134502)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
2. SHIMURA Yoshiro (60025426)

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Yokoyama Shigeyuki 横山 茂之

YOKOYAMA Shigeyuki 横山 茂之

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Structural analysis of neo-selfPrincipal Investigator

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Structural analysis of HLA class I/II moleculesPrincipal Investigator

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Crystallographic studies of macromolecular complexes in transcription and translation : RNA polymerases and the ribosomePrincipal Investigator

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Structural and functional studies on biological macromolecules involved in the flow of genetic information and the cellular signal transduction.Principal Investigator

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Structure of RNA and RNPPrincipal Investigator

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Yokoyama Shigeyuki 横山茂之

YOKOYAMA Shigeyuki 横山茂之