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Ito Mamoru  伊藤 守

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ITO MAMORU  伊藤 守

ITO Mamoru  伊藤 守

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Researcher Number 00176364
Other IDs
Affiliation (Current) 2025: 公益財団法人実中研, 役員, 理事
Affiliation (based on the past Project Information) *help 2019 – 2021: 公益財団法人実験動物中央研究所, 役員, 所長
2018: 公益財団法人実験動物中央研究所, 研究部門, 副所長
2012 – 2014: 公益財団法人実験動物中央研究所, その他部局等, 研究員
2011: 公益財団法人実験動物中央研究所, 実験動物研究部, 部長
2010 – 2011: Central Institute for Experimental Animals, 研究員 … More
2010: Central Institute for Experimental Animals, 免疫研究室, 室長
2010: 財団法人実験動物中央研究所, 実験動物研究部, 研究員
2009: Central Institute for Experimental Animals, 免疫研究室, 室長
2008: 東北大学, 実験動物中央研究所・免疫研究, 室長
2007 – 2008: Central Institute for Experimental Animals, 免疫研究室, 室長
2007: (財)実験動物中央研究, 免疫研究室, 室長
2006: (財)実験動物中央研究所, 免疫研究室, 室長
2003 – 2004: CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS, IMMUNOLOGY LABORATORY, CHIEF RESEARCHER, 免疫研究室, 室長
2003 – 2004: 財団法人実験動物中央研究所, 免疫研究室, 室長
1999 – 2004: Central Institute for Experimenatl Animals, Lab.of Immunology, Senior Scientist, 免疫研究室, 室長
2002 – 2003: 実験動物中央研究所, 免疫研究室, 室長(研究職)
2002: (財)実験動物中央研究所, 免疫研究室, 室長(研究職)
2002: Central Institute for Experimental Animals, Laboratory of Immunology, Head, 免疫研究室, 室長
1999 – 2002: 実験動物中央研究所, 研究員
2001: 実験動物中央研究所, 免疫研究室, 室長
2000 – 2001: Central Institute for Experimental Animal Senior Scientist, 室長(研究職)
1999: 財団法人 実験動物中央研究所, 室長(研究職)
1999: 財団法人 実験動物中央研究所, 免疫研究室, 室長
1998 – 1999: 実験動物中央研究所, 免疫研究室, 主任研究員
1997 – 1999: 実験動物中央研究所, 免疫研究室, 室長
1998: (財)実験動物中央研究所, 免疫研, 室長
1998: 実験動物中央研究所, 免疫研, 室長
1998: Central Institute for Experimental Animals, Chief of Immunology, 免疫研究所, 室長
1997 – 1998: (財)実験動物中央研究所, 室長
1997 – 1998: 財, 実験動物中央研究所・免疫研究室, 室長
1997: CENTRAL RESEARCH INSTITUTE FOR ANIMAL EXPERIMENT,HEAD OF RESEARCHER, 実験動物中央研究所, 主任研究員
1997: Central Institute for Experimental Animal. Senior Staff, 室長(研究職)
1996 – 1997: 財団法人実験動物中央研究所, 免疫研究室, 室長
1995 – 1997: 実験動物中央研究所, 研究員
1996: (財)実験動物中央研究所, 免疫研究室, 室長
1996: 財団法人実験動物中央研究所, 免疫学研究室, 室長
1995: 財団法人 歛験動物中央研究所, 免疫学研究室, 室長
1994: CIEA,Immunology Lab., Head of Lab., 免疫研, 室長
1994: Central Institute for Experimental Animals, Investigator, 研究員
1994: 実験動物中央研究所, 免疫研究室, 室長
1994: 財団法人実験動物中央研究所, 免疫学研究室, 室長
1994: 財団法人実験動物中央研究所, 免疫研, 室長
1993: (財)実中研, 免疫, 室長
1993: (財)実験動物中央研究所, 免疫研究室, 室長
1993: Central Institute for Experimental Animals, Investigator, 免疫研究室, 研究員
1993: 実験動物中央研究所, 免疫研究室, 研究員
1993: 東海大学, 実験動物中央研究所, 室長
1992: (財)実験動物中央研究所, 免疫, 室長
1992: 実験動物中央研究所, 研究員
1992: 財団法人実験動物中央研究所, 免疫研究室, 室長
1990 – 1992: (財)実験動物中央研究所, 研究員
1989 – 1992: (財)実験動物中央研究所, 免疫研究室, 研究員
1991: CIEA, Immunol Lab, Chief Scientist, 免疫研究室, 室長
1991: (財)実験動物中央研究所, 免疾研究室, 室長
1988: Central Inst. Exp. Anim., 研究員
1988: 実験動物中央研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Laboratory animal science / Laboratory animal science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Except Principal Investigator
Laboratory animal science / 寄生虫学(含医用動物学) / Biological Sciences / 基礎獣医学 / Hematology / 広領域 / Immunology / 寄生虫学(含医用動物学) / 物質生物化学
Keywords
Principal Investigator
実験動物 / 免疫不全マウス / 分化 / HTLV-1 / HIV-1 / 異種移植 / experimental animals / ES細胞 / China / 実験動物化 … More / Lagurus lagurus / 中国 / ヒト化マウス / ヒト化モデル / NOGマウス / 免疫 / 脳性マラリア / 細胞接着因子 / 動物モデル / 新世界ザル / iPS / IPS細胞 / 胸腺 / 造血幹細胞 / iPS細胞 / Differentiation / Rat / ES cells / NOG mice / Animal model / Regenerative medicine / 同種移植 / 再生医学 / 分化誘導 / ラット / 再生治療 / Phylogeny / Immunology / Model for infectious diseases / Experimentation / Gerbil / 系統進化 / 感染症モデル / スナネズミ / CD34+ stem cells / Xenotransplantation / Immunodeficiency / NOD-scid. γc null mice / NOD-scid,γKOマウス / CD34+細胞 / 免疫不全 / NOD-scid, γKOマウス / mitochondria / embryonic stem cells / nuclear transfer / cloned mice / ヘテロプラスミー / ミトコンドリア / 核移植 / クローン動物 / Echinococcosis / Leishmaniasis / Infectious diseases / Experimental animal / Wild rodents / Xinjiang-Uygur / クリプトスポリジウム / 野生動物 / レミング / リーシュマニア / エキノコックス / 感染症 / 草原レミング / 野生齧歯類 / 新疆・ウィグル自治区 / 個別衣料 / 免疫不全動物 / 個別化医療 / 個別医療 / 実験動物学 / ヒト疾患モデル / 発生・分化 / ヒト化動物モデル / 病態モデル / ICAM-1 / トランスジェニックマウス / 免疫グロブリン / リンパ球 / モノクローナル抗体 / リンパ球抗原 / 熱帯熱マラリア / SCIDマウス / PCR / 診断 / 化学療法 / 消毒 / ニュ-モシスティス・カリニ / 栄養体 / 消毒薬 / pneumocystis carinii … More
Except Principal Investigator
AIDS / Echinococcus / テニア科条虫 / Zoonosis / 人獣共通感染症 / エキノコックス / 寄生虫 / Taenia / 免疫 / FLT3 / RAG1・RAG2 / MAPK / Arthropod-borne Infection / Pathogenic protozoa / Central Eurasia / 中央アジア / リーシュマニア症 / Trypanosoma cruzi / Echinococcus multilocularis / Trichinella britovi / Schistosoma mansoni / Pneumocystis carinii / 日和見感染症 / ニューモシスチス・カリニ肺炎 / ニューモシスチス・カリニ / Prednisolone / スナネズミ / 系統保存 / ラット / マウス / 免疫不全 / SCIDマウス / 胸腺細胞 / positive selection / 疾患モデル / Heteromydae / Cricetidae / Alternative / Worm-expulsion / Golden hamster / ゴールデンハムスター / 代替動物 / 消化管粘膜 / Heteromydae(ポケットマウス科) / worm-expulsion(虫体排除) / Heterromydae(ポケットマウス科) / Cricetidae(キヌゲネズミ科) / alternative(代替動物) / prednisolone(プレドニゾロン) / worm-expulision(虫体排除) / golden hamster(ゴ-ルデンハムスタ-) / Echinococcus(エキノコックス) / Taenia(テニア属) / immunity / biological control / antagonistic competition / laboratory animal / vole / Clethrionomys / 生物的防除 / 局所免疫 / 生物防除 / 猫条虫 / 生物 防除 / 種間競合 / 実験動物化 / エゾヤチネズミ / 多包条虫 / Molecularly targeted thrapy / transgenic mouse / Leukemia / 変異FLT3 / 骨髄移植モデル / 分子標的療法 / トランスジェニックマウス / 白血病 / disease model mice / ES cells / embryo cloning / mdx mice / dy mice / NOD mice / 糖尿病 / 筋ジストロフィー / クローン / Neuronal death / Neurofibrillary tangles / Tau / Alzheimer's disease / 神経細胞死 / 神経原線維変化 / タウ蛋白 / アルツハイマー病 / antibodies / phage display method / faiciparm malaria / Thalland / genes related to servere malaria / mouse severe malaria / ヘパラン硫酸 / 補体レセプター1型(CR1) / ロゼット / マラリア流行 / 重症化 / 熱帯熱マラリア / マラリア抗原 / マラリア抗体 / 熱帯熱マラリア患者 / CD14 / 第18染色体 / 抗体 / ファージ・ディスプレー法 / 熱帯マラリア / タイ国 / 重症マラリア感受性遺伝子 / マウス重症マラリア / human cancer / knock-out mouse / common γchain / animal model / immunodeficiency / NK細胞 / ヒト癌細胞 / ノックアウトマウス / コモンγ鎖 / Taenia solium / Taenia saginata / taeniid cestode / experimental animal model for cysticercosis / echinococcosis / cysticercosis / severe combined immunodeficient (scid)mouse / 多包虫 / ネコ条虫 / 実験動物モデル / 免疫不全動物 / 脳嚢虫症 / 有鉤嚢虫症 / 有鉤条虫 / 無鉤条虫 / 病態モデル動物 / エキノコックス症 / 有鉤襄虫症 / 免疫不全マウス / Irrigation of deserts / Epidemiology / Visceral Leishmaniasis / Cutaneous Leishmaniasis / 内蔵型リーシュマニア症 / 砂漠 / 疫学 / 無脊椎動物媒介性疾患 / リーシュマニア原虫 / 内臓型リーシュマニア症 / 皮膚型リーシュマニア症 / thymocyte / gene rearrangement / proliferative inhibition / T cell receptor / germ line転写 / シスエレメント / TCR / 遺伝子再構成 / 正の選択的分化 / 細胞増殖抑制 / T細胞レセプター / Molecular Epidemiology / Great gerbils / irrigation of deserts / Leishmaniasis / 中華人民共和国 / 節足動物媒介性感染症 / 分子疫学 / 病原性原虫 / オオスナネズミ / 砂漠の緑地化 / 中央ユーラシア / Reproductive performance / Growth curve / Mini-pigs / 繁殖成績 / 発育比較 / 小型ブタ / infection kinetic / drug resistance / SCID mouse / Trypanosomagrosi / Trichinella spiralis / Trichimella spiralis / Trypanosoma spp. / 感染動態 / 薬剤耐性 / Trypanosoma grosi / Opportunistic Infection / Monoclonal Antibody / Pneumocystis carinii Pneumonia / Schizodeme analysis / ribosomal DNA / モノクローナル抗体 / scid mouse / therapeutic agent / aculeacin / glucan / opportunistic infection / Pneumocystis carinii pneumonia / スキッド・マウス / 化学療法薬 / アクレアシン / グルカン / 日和見感染性 / Strain / Rat / Transplantation / 動物実験系 / 心臓移植 / ラット系統 / 系統 / 移植 / Host specificity / Immunodiagnosis / American rodents / Mongolian gerbil / Hamster / Alternative host / Dipodomys / Perognathus / 獲得抵抗性 / モデル動物 / ハムスタ- / イヌ / 虫体ES抗原 / Coproantigen / ELISA / コレステロール / プレドニゾロン / 宿主特異性 / 免疫診断 / 南北米産齧歯類 / ハムスター / プリドニゾロン / 代替宿主 / Preservation of Strains / Embryo Bank / Embryo Cryopreservation / Embryos / Animal Models for Human Diseases / Rats / Mice / Laboratory Animals / バイオサイエンス / エンブリオバンク / 胚の凍結保存 / 胚 / ヒト疾患モデル動物 / 実験動物 / ヒト抗体 / ヒト型マウス / ヒト免疫 / IgGクラススイッチ / MHC class II / 免疫系ヒト化NOGマウス / HLA-DRトランスジェニックマウス / NOGマウス / 免疫系ヒト化マウス / 免疫不全症 / ヒト化マウス / ヒト免疫系 / フローサイトメトリー / CD34 / サル骨髄抑制モデル / カニクイザル / マ-モセット / 胸腺 / リンパ節 / ヒトリンパ球構築 / エイズモデル動物 / HIV / MHC拘束性 / negative selection / T細胞抗原レセプター(TCR) / トランスジエニックマウス / 微生物 / 遺伝 / 遺伝子マッピング / モニタリング / 品質管理 / 疾患パラメーター / 疾患モデル系統 / 突然変異 / ゲノム / トランスジェニック / マッピング / PCR / 遺伝子診断 / マイクロサテライトマーカー Less
  • Research Projects

    (35 results)
  • Research Products

    (161 results)
  • Co-Researchers

    (102 People)
  •  Approaches to standardization of humanized mice by transplanting human hematopoietic stem cells (HSC) and thymus generated from induced pluripotent stem (iPS) cells.Principal Investigator

    • Principal Investigator
      ITO MAMORU
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Central Institute for Experimental Animals
  •  Development of experimentation systems related to personalized medicine using humanized NOG micePrincipal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Establishment of humanized immune mice and its application for study of human immune system of human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      地方独立行政法人宮城県立病院機構 宮城県立がんセンター(研究所)
      Miyagi Cancer Center Research Institute
      Tohoku University
  •  Basic study to establish "humanized animal model" by improvement and modification of severely immunodeficient NOG mousePrincipal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Basic studies on animal model for regenerative medicine using severe immunodeficient mice.Principal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Practical use of cloning technology for NOD and dy disease model mice production

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE
  •  The studies on the practical application of NOD-sc/d, yc null mice allowing an efficient transplantation of human cells, to human disease modelsPrincipal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Study on their experimetation of gerbils living in China for infectious diseases.Principal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Establishment of a leukemia model mouse by introducing mutated FLT3 gene

    • Principal Investigator
      NAOE Tomoki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Hyperphosphorylation and aggregation of tau protein, and neuronal death

    • Principal Investigator
      IHARA Yasuo
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Generation of cloned mice and application on the field of laboratory animal sciencePrincipal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Genomic factors of parasites and human beings on malaria severity

    • Principal Investigator
      AIKAWA Masamichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokai University
  •  Epidemiology and Control of Leishmaniasis in Central Eurasia ; A new epidemic in association with irrigation of deserts

    • Principal Investigator
      MATSUMOTO Yoshitsugu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Development of Chinese Lemming as an Experimental AnimalPrincipal Investigator

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  SEVERE COMBINED IMMUNODEFICIENT (SCID) MICE AS ANIMAL MODELS FOR HUMAN CYSTICERCOSIS AND ECHINOCOCCOSIS (1999)

    • Principal Investigator
      ITO Akira
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      ASAHIKAWA MEDICAL COLLEGE
  •  Lymphocyte deficient mice as hosts for xenograft of human cells

    • Principal Investigator
      NAKAMURA Masataka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒト細胞接着因子導入Tg-SCDIマウスを用いたヒト脳性マラリアモデルの開発Principal Investigator

    • Principal Investigator
      伊藤 守
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  Molecular mechanism of selective development in thymocytes analysing DP specific molcules

    • Principal Investigator
      HABU Sonoko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tokai University
  •  新世界ザルのリンパ球表面抗原に対するモノクローナル抗体の作製とその抗原の機能分析Principal Investigator

    • Principal Investigator
      伊藤 守
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Characterization as experimental animals on mini-pigs in China

    • Principal Investigator
      TANIOKA Yoshikuni
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Epidemiology and Control of Leishmaniasis in Cetral Eurasia ; A new epidemic in association with irrigation of deserts

    • Principal Investigator
      MATSUMOTO Yoshitsugu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      The University of Tokyo
  •  ESTABLISHMENT OF ANIMAL MODEL USING SCID MICE FOR ANALYSIS OF DRUG RESISTANCE AGAINST PARSITIC NEECTIONS

    • Principal Investigator
      KAMIYA Haruo
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      HIROSAKI UNIVERSITY
  •  SCIDマウスによるHIV病原性の解析

    • Principal Investigator
      KOYANAGI Yoshio
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  霊長類によるヒト代替骨髄抑制モデルの開発ならびに造血機能に関する研究

    • Principal Investigator
      鈴木 修三
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  胸腺内分化モデルの確立による自己認識T細胞クローンの選択に関する分子免疫学研究

    • Principal Investigator
      HABU Sonoko
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  新世界ザルを用いたヒト熱帯熱マラリアモデルの開発Principal Investigator

    • Principal Investigator
      伊藤 守
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Immunological and Genetical Heterogeneity of Pneumocystis carinii

    • Principal Investigator
      MATSUMOTO Yoshitsugu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      University of Tokyo
  •  疾患モデル系統における疾患形質パラメーターによる形質モニタリングの確立

    • Principal Investigator
      KATOH Hideki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Central Institute for Experimental Animals
  •  The standerdization of rat strains for the transplant-immunology and establithment for screening systems of immunosupresive matters

    • Principal Investigator
      NOMURA Tatsuji
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Gentral Institute for Experimental Animals
  •  Polysaccharide of Pneumocystis carinii cyst wall as a new target for therapy

    • Principal Investigator
      MATSUMOTO Yoshitsugu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      University of Tokyo
  •  ニューモシスティス・カリニ感染に対する防除方法の研究Principal Investigator

    • Principal Investigator
      伊藤 守
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  ESTABLISHMENT AND USE OF ALTERNATIVE DEFINITIVE HOSTS FOR ECHINOCOCCUS

    • Principal Investigator
      KAMIYA Masao
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Establishment of an Embryo Bank System for Laboratory Animals

    • Principal Investigator
      NOMURA Tatsuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS (CIEA)
  •  Expulsion mechanism of adult-taeniid cestodes induced by mucosal responses of definitive hosts.

    • Principal Investigator
      KAMIYA Masao
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      基礎獣医学
    • Research Institution
      Hokkaido University
  •  Establishment and application of the laboratory colony of Clethrionomys rufocanus bedfordiae susceptible to Echinococcus multilocularis for the antagonistic competion among taeniid species

    • Principal Investigator
      KAMIYA Masao
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Hokkaido University

All 2019 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 Other

All Journal Article Presentation Book Patent

  • [Book] NOGマウス2019

    • Author(s)
      伊藤守
    • Total Pages
      4
    • Publisher
      公益社団法人日本実験動物協会 Labio 21
    • ISBN
    • Data Source
      KAKENHI-PROJECT-18H03975
  • [Book] Humanized Mice for HIV Research2015

    • Author(s)
      Ito, R. Katano, I. Ito, M.
    • Total Pages
      538
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Book] Humanized Mice for HIV Research2015

    • Author(s)
      Ito, M.
    • Total Pages
      538
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Book] LABIO 212014

    • Author(s)
      伊藤守
    • Total Pages
      2
    • Publisher
      公益財団法人日本実験動物協会
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Book] モデル動物利用マニュアルシリーズ「生体機能モデルと新しいリソース・リサーチツール」2011

    • Author(s)
      伊藤守
    • Total Pages
      671
    • Publisher
      (株)エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Book] モデル動物利用マニュアルシリーズ「疾患モデルの作製と利用-免疫疾患」2011

    • Author(s)
      伊藤守
    • Total Pages
      580
    • Publisher
      (株)エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Book] モデル動物利用マニュアルシリーズ(「生体機能モデルと新しいリソース・リサーチツール」)2011

    • Author(s)
      伊藤守
    • Total Pages
      671
    • Publisher
      (株)エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Journal Article] Humanized mouse models: Application to human diseases2017

    • Author(s)
      Ito Ryoji、Takahashi Takeshi、Ito Mamoru
    • Journal Title

      J Cell Physiol.

      Volume: 233 Issue: 5 Pages: 3723-3728

    • DOI

      10.1002/jcp.26045

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07103, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-18H03975
  • [Journal Article] Visualization of the human CD4(+) T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/gammac(null) (NOG) mice by retrogenic expression of the human TCR gene2015

    • Author(s)
      Takahashi, T. Katano, I. Ito, R. Ito, M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 456 Issue: 1 Pages: 219-224

    • DOI

      10.1016/j.bbrc.2014.11.062

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-25871075, KAKENHI-PROJECT-26290034
  • [Journal Article] Predominant Development of Mature and Functional Human NK Cells in a Novel Human IL-2-Producing Transgenic NOG Mouse2015

    • Author(s)
      Katano, I. Takahashi, T. Ito, R. Kamisako, T. Mizusawa, T. Ka, Y. Ogura, T. Suemizu, H. Kawakami, Y. Ito, M.
    • Journal Title

      J Immunol

      Volume: 194 Issue: 7 Pages: 3513-3525

    • DOI

      10.4049/jimmunol.1401323

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-25871075, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-26290034, KAKENHI-PROJECT-25430099
  • [Journal Article] APOBEC3D and APOBEC3F Potently Promote HIV-1 Diversification and Evolution in Humanized Mouse Model2014

    • Author(s)
      Sato, K. Takeuchi, J. S. Misawa, N. Izumi, T. Kobayashi, T. Kimura, Y. Iwami, S. Takaori-Kondo, A. Hu, W. S. Aihara, K. Ito, M. An, D. S. Pathak, V. K. Koyanagi, Y.
    • Journal Title

      PLoS Pathog

      Volume: 10 Issue: 10 Pages: e1004453-e1004453

    • DOI

      10.1371/journal.ppat.1004453

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-24115008, KAKENHI-PROJECT-24390112, KAKENHI-PROJECT-26287025, KAKENHI-PROJECT-26670168
  • [Journal Article] Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice2014

    • Author(s)
      Matsushita, H. Yahata, T. Sheng, Y. Nakamura, Y. Muguruma, Y. Matsuzawa, H. Tanaka, M. Hayashi, H. Sato, T. Damdinsuren, A. Onizuka, M. Ito, M. Miyachi, H. Pandolfi, P. P. Ando, K.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 11 Pages: e111082-e111082

    • DOI

      10.1371/journal.pone.0111082

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-24590361, KAKENHI-PROJECT-24591411, KAKENHI-PROJECT-26430094
  • [Journal Article] Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged-12014

    • Author(s)
      Negishi, N. Suzuki, D. Ito, R. Irie, N. Matsuo, K. Yahata, T. Nagano, K. Aoki, K. Ohya, K. Hozumi, K. Ando, K. Tamaoki, N. Ito, M. Habu, S.
    • Journal Title

      Exp Hematol

      Volume: 42 Issue: 6 Pages: 487-94

    • DOI

      10.1016/j.exphem.2014.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-24590361, KAKENHI-PROJECT-25430099
  • [Journal Article] NOD-Rag2(null) IL-2Rgamma(null) Mice: An Alternative to NOG Mice for Generation of Humanized Mice2014

    • Author(s)
      Katano, I. Ito, R. Kamisako, T. Eto, T. Ogura, T. Kawai, K. Suemizu, H. Takahashi, T. Kawakami, Y. Ito, M.
    • Journal Title

      Exp Anim

      Volume: 63 Pages: 321-30

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Journal Article] HIV-1 Vpr accelerates viral replication during acute infection by exploiting proliferating CD4+ T cells in vivo.2013

    • Author(s)
      Sato K, Misawa N, Iwami S, Satou Y, Matsuoka M, Ishizaka Y, Ito M, Aihara K, An DS, and Koyanagi Y
    • Journal Title

      PLoS Pathogens

      Volume: 9 Issue: 12 Pages: e1003812-e1003812

    • DOI

      10.1371/journal.ppat.1003812

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22114003, KAKENHI-PROJECT-22220007
  • [Journal Article] Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells.2013

    • Author(s)
      Hirose, S., N. Takayama, S. Nakamura, K. Nagasawa, K. Ochi, S. Hirata, S. Yamazaki, T. Yamaguchi, M. Otsu, S. Sano, N. Takahashi, A. Sawaguchi, M. Ito, T. Kato, H. Nakauchi, and K. Eto.
    • Journal Title

      Stem Cell Reports

      Volume: 1 Issue: 6 Pages: 499-508

    • DOI

      10.1016/j.stemcr.2013.10.010

    • NAID

      120005350227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
  • [Journal Article] Establishment of a Human Allergy Model Using Human IL-3/GM-CSF-Transgenic NOG Mice.2013

    • Author(s)
      Ito, R., T. Takahashi, I. Katano, K. Kawai, T. Kamisako, T. Ogura, M. Ida-Tanaka, H. Suemizu, S. Nunomura, C. Ra, A. Mori, S. Aiso, and M. Ito.
    • Journal Title

      J Immunol

      Volume: 191 Issue: 6 Pages: 2890-2899

    • DOI

      10.4049/jimmunol.1203543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-23590561, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-25871075
  • [Journal Article] Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome.2013

    • Author(s)
      Saida, S., K. Watanabe, A. Sato-Otsubo, K. Terui, K. Yoshida, Y. Okuno, T. Toki, R. Wang, Y. Shiraishi, S. Miyano, I. Kato, T. Morishima, H. Fujino, K. Umeda, H. Hiramatsu, S. Adachi, E. Ito, S. Ogawa, M. Ito, T. Nakahata, and T. Heike.
    • Journal Title

      Blood

      Volume: 121 Issue: 21 Pages: 4377-4387

    • DOI

      10.1182/blood-2012-12-474387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23890092, KAKENHI-PROJECT-24659496, KAKENHI-PLANNED-22134006
  • [Journal Article] Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rgammanull mice is attributed to a lack of CD11c+B220+CD122+ cells2012

    • Author(s)
      Ito, R.
    • Journal Title

      J Immunol

      Volume: 189 Issue: 9 Pages: 4313-20

    • DOI

      10.4049/jimmunol.1200820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
  • [Journal Article] ヒト化マウスの改良と疾患モデルへの応用2012

    • Author(s)
      伊藤守
    • Journal Title

      実験医学

      Volume: 30 Pages: 154-159

    • Data Source
      KAKENHI-PROJECT-22220007
  • [Journal Article] Current advances in humanized mouse models2012

    • Author(s)
      Ito, R.
    • Journal Title

      Cell Mol Immunol

      Volume: 9 Issue: 3 Pages: 208-14

    • DOI

      10.1038/cmi.2012.2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
  • [Journal Article] Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts2012

    • Author(s)
      Ito, R.
    • Journal Title

      Exp Hematol

      Volume: 40 Issue: 11 Pages: 953-963

    • DOI

      10.1016/j.exphem.2012.07.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
  • [Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/ γ cnull mouse.2012

    • Author(s)
      Suzuki M, Takahashi T, Katano T, Ito R, Ito M, Harigae H, Ishii N, Sugamura K.
    • Journal Title

      Int. Immunol.

      Volume: 24 Pages: 243-252

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] ヒト化マウスの現状2010

    • Author(s)
      伊藤守
    • Journal Title

      細胞工学

      Volume: 29 Pages: 238-242

    • Data Source
      KAKENHI-PROJECT-22220007
  • [Journal Article] Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.2010

    • Author(s)
      Saito Y, Ishikawa F, et al
    • Journal Title

      Nature Biotechnology 28-3

      Pages: 275-280

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Molecular Phylogeny of the Subfamily Gerbillinae(Muridae, Rodentia)with Emphasis on Species Living in the Xinjiang-Uygur Autonomous Region of China and Based on the Mitochondrial Cytochrome b and Cytochrome c Oxidase Subunit II Genes2010

    • Author(s)
      Ito,M.
    • Journal Title

      Zoolog Sci 27

      Pages: 269-278

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Molecular Phylogeny of the Subfamily Gerbillinae(Muridae, Rodentia)with Emphasis on Species Living in the Xinjiang-Uygur Autonomous Region of China and Based on the Mitochondrial Cytochrome b and Cytochrome c Oxidase Subunit II Genes2010

    • Author(s)
      Ito, M., W.Jiang, J.J.Sato, Q.Zhen, W.Jiao, K.Goto, H.Sato, K.Ishiwata, Y.Oku, J.J.Chai, H.Kamiya
    • Journal Title

      Zoolog Sci 27

      Pages: 269-278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] ヒト化マウスの現状と将来展望2010

    • Author(s)
      伊藤守
    • Journal Title

      MDS(Medical Science Digest)

      Volume: 37 Pages: 44-45

    • Data Source
      KAKENHI-PROJECT-22220007
  • [Journal Article] ヒト化マウスの現状2010

    • Author(s)
      伊藤守
    • Journal Title

      細胞工学 29

      Pages: 238-242

    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Regulatory T cells are necessary for implantation and maintenance of early pregnancy but not ate pregnancy in allogeneic mice.2010

    • Author(s)
      Shima, T., Sasaki, Y., Itoh, M., Nakashima, A., Ishii, N., Sugamura, K. and Saito, S.
    • Journal Title

      J. Rep. Immunol.

      Volume: 85 Pages: 121-129

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009

    • Author(s)
      Ito R., I.Katano, K.Kawai, H.Hirata, T.Ogura, T.Kamisako, T.Eto, M.Ito
    • Journal Title

      Transplantation 87

      Pages: 1654-1658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K
    • Journal Title

      Int Immunol

      Volume: 21 Pages: 843-858

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2009

    • Author(s)
      Ito M, Kobayashi K, Nakahata T.
    • Journal Title

      Curr Top Microbiol Immunol

      Volume: 324 Pages: 53-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rgammanull mice.2009

    • Author(s)
      Nie C., K.Sato, N.Misawa, H.Kitayama, H.Fujino, H.Hiramatsu, T.Heike, T.Nakahata, Y.Tanaka, M.Ito, Y.Koyanagi
    • Journal Title

      Virology 394

      Pages: 64-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice2009

    • Author(s)
      Ito, R., I. Katano, K. Kawai, H. Hirata, T. Ogura, T. Kamisako, T. Eto, and M. Ito.
    • Journal Title

      Transplantation 87

      Pages: 1654-1658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009

    • Author(s)
      Ito R, Katano I, Kawai K, Hirata H, Ogura T, Kamisako T, Eto T, Ito M.
    • Journal Title

      Transplantation

      Volume: 87 Pages: 1654-1658

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009

    • Author(s)
      Ito R, Katano I, Kawai K, Hirata H, 0gura T, Kamisako T, Eto T, and Ito M.
    • Journal Title

      Transplantaion

      Volume: 87 Pages: 1654-1658

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull(NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, 0kajima A, Shiokawa M, Ishii N, Katano I,Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S and Sugamura K.
    • Journal Title

      Int. Immunol.

      Volume: 21 Pages: 843-858

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009

    • Author(s)
      Ito R, Ito M, et al
    • Journal Title

      Transplantation 87

      Pages: 1654-1658

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Highly sensitive model for xenogenic-GVHD using severe immunodeficient NOG mice2009

    • Author(s)
      Ito, R.
    • Journal Title

      Transplantation 87(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, Ito M, Sugamura K, et al
    • Journal Title

      Int. Immunol. 21

      Pages: 843-858

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] NOGマウスとヒト化マウス2009

    • Author(s)
      伊藤守
    • Journal Title

      ファルマシア 45

      Pages: 1077-1081

    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis.2008

    • Author(s)
      Yahata T., Y.Muguruma, S.Yumino, Y.Sheng, T.Uno, H.Matsuzawa, M.Ito, S.Kato, T.Hotta, K.Ando
    • Journal Title

      Stem Cells 26

      Pages: 3228-3236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Humanized mice for human retrovirus infection.2008

    • Author(s)
      Koyanagi Y., Y.Tanaka, M.Ito, N.Yamamoto
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 133-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.2008

    • Author(s)
      Suemizu H., M.Hasegawa, K.Kawai, K.Taniguchi, M.Monnai, M.Wakui, M.Suematsu, M.Ito, G.Peltz, M.Nakamura
    • Journal Title

      Biochem Biophys Res Commun 377

      Pages: 248-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2008

    • Author(s)
      Ito M., K.Kobayashi, T.Nakahata
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 53-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models2008

    • Author(s)
      Ito, M.
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 53-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] NOD/Shi-scid IL2rgamma (null) (NOG) micemore appropriate for humanized mouse models2008

    • Author(s)
      Ito, M., K. Kobayashi, and T. Nakahata.
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 53-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Antigen-specific antibody production of human B cells in NOG mice reconstituted with the human immune system.2008

    • Author(s)
      Ito R., M.Shiina, Y.Saito, Y.Tokuda, Y.Kametani, S.Habu
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 95-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses.2008

    • Author(s)
      Yajima M., K.Imadome, A.Nakagawa, S.Watanabe, K.Terashima, H.Nakamura, M.Ito, N.Shimizu, M.Honda, N.Yamamoto, S.Fujiwara
    • Journal Title

      J Infect Dis 198

      Pages: 673-682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis2008

    • Author(s)
      T., Y. Muguruma, S. Yumino, Y. Sheng, T. Uno, H. Matsuzawa, M. Ito, S. Kato, T. Hotta, and K. Ando.
    • Journal Title

      Stem Cells 26

      Pages: 3228-3236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice2008

    • Author(s)
      Suemizu, H., M. Hasegawa, K. Kawai, K. Taniguchi, M. Monnai, M. Wakui, M. Suematsu, M. Ito, G. Peltz, and M. Nakamura.
    • Journal Title

      Biochem Biophys Res Commun 377

      Pages: 248-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Establishing EGFP congenic mice in a NOD/Shi-scid IL2Rg(null) (NOG) genetic background using a marker-assisted selection protocol (MASP).2008

    • Author(s)
      Suemizu H., C.Yagihashi, T.Mizushima, T.Ogura, T.Etoh, K.Kawai, M.Ito
    • Journal Title

      Exp Anim 57

      Pages: 471-477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] NOD/Shi IL2rg<null>(NOG) mice appropriate for humanized mouse models.2008

    • Author(s)
      Ito M, Kobayashi K, Nakahata T
    • Journal Title

      "Humanized mice" , Nomura T, et al.(eds.), Current Topics in Microbiol. and Immunol., Springer-Verlag Berlin Heidelberg

      Volume: 324 Pages: 53-76

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Interferon-alpha 2b-induced thrombocytopenia is caused by inhibition of platelet production but not proliferation and endomitosis in human megakaryocytes.2008

    • Author(s)
      Yamane A., T.Nakamura H.Suzuki M.Ito, Y.Ohnishi, Y.Ikeda, Y.Miyakawa
    • Journal Title

      Blood 112

      Pages: 542-550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Development of human Graafian follicles following transplantation of human ovarian tissue into NOD/SCID/gammacnull mice.2008

    • Author(s)
      Terada Y., Y.Terunuma-Sato, T.Kakoi-Yoshimoto, H.Hasegawa, T.Ugajin, Y.Koyanagi, M.Ito, T.Murakami, H.Sasano, N.Yaegashi, K.Okamura
    • Journal Title

      Am J Reprod Immunol 60

      Pages: 534-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2008

    • Author(s)
      Ito M, Kobayashi K, Nakahata T
    • Journal Title

      Curr Top Microbiol Immunol 324

      Pages: 53-76

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Interleukin-4-transgenic hu-PBL-SCID mice: A model for the screening of antiviral drugs and immunotherapeutic agents against X4 HIV-1 viruses.2008

    • Author(s)
      Okuma K, Tanaka r, Ogura T, Ito M, Kumakura S, Yanaka M, Nishizawa M, Sugiura W, Yamamoto N, Tanaka Y
    • Journal Title

      J. Infect. Dis.

      Volume: 197 Pages: 134-141

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] NOD/Shi-scid IL2rgamma(null)(NOG) mice more appropriate for humanized mouse models.2008

    • Author(s)
      Ito M, Kobayashi K and Nakahata T.
    • Journal Title

      Curr. Top. Microbiol. Immunol.

      Volume: 324 Pages: 53-76

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] A new humanized mouse model of Epstein-Barrvirus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses2008

    • Author(s)
      Yajima, M., K. Imadome, A. Nakagawa, S. Watanabe, K. Terashima, H. Nakamura, M. Ito, N. Shimizu, M. Honda, N. Yamamoto, and S. Fujiwara.
    • Journal Title

      J Infect Dis 198

      Pages: 673-682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] 特集:動物とヒトの比較腫瘍学、異種移植系の宿主側の検討2008

    • Author(s)
      伊藤 守
    • Journal Title

      アニテックス 19

      Pages: 13-19

    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis.2008

    • Author(s)
      Yahata, T, Muguruma Y, Yumino S, Sheng Y, Uno T, Matsuzawa H, Ito M, Kato S, Hotta T, and Ando K.
    • Journal Title

      Stem Cells

      Volume: 26 Pages: 3228-3236

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in the NOD-SCTD/IL2rg^<null> mice.2008

    • Author(s)
      Ishikawa F, Saito Y, Yoshida S, Harada M, Shultz LD.
    • Journal Title

      Curr TopMicrobiol Immunol

      Volume: 324 Pages: 87-94

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] The origins of blood: induction of hematopoietic stem cells from different sources.2008

    • Author(s)
      Saito Y and Ishikawa F.
    • Journal Title

      Cell Stem Cell

      Volume: 3 Pages: 8-10

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCTD/gamma(c)null mice through cell fusion.2007

    • Author(s)
      Fujino H, Hiramatsu H, Tsuchiya A, Niwa A, Noma H, Shiota M, Umeda K, Yoshimoto M, Ito M, Heike T, Nakahata T
    • Journal Title

      Faseb J.

      Volume: 21 Pages: 3499-3510

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Noninvasive and real-time assessment of reconstructed functional human endortrium in NOD/SCID/{gamma}formula immunodeficient mice.2007

    • Author(s)
      Masuda H, Maruyama T, Hiratsu E, Yamane J, Iwanami A, Nagashima T, 0no M, Miyoshi H, 0kano HJ, Ito M, Tamaoki N, Nomura T, 0kano H, Matsuzaki Y, Yoshimura Y
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 104 Pages: 1925-1930

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Humanized NOD/SCTD/IL2R{gamma}null mice transplanted with hematopoietic stem cells under non-myeloablative condition show prolonged lifespans and allow detailed analysis of HIV-1 pathogenesis.2007

    • Author(s)
      Watanabe S, 0hta S, Yajima M, Terashima K, Ito M, Mugishima H, Fujiwara S, Shimizu K, Honda M, Shimizu N, Yamamoto N
    • Journal Title

      J. Virol.

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Chemotherapy-resistant human AML stem cells home to and engraft within the bone marrow endsteal region.2007

    • Author(s)
      Ishikawa F, Yoshida S, Saito Y, Hijikata A, Kitamura H, Tanaka S, Nakamura R, Tanaka T, Tomiyama H, Saito N, Fukata M, Miyamoto T, Lyons B, 0hshima K, Uchida N, Taniguchi S, 0hara 0, Akashi K, Harada M, Shultz LD.
    • Journal Title

      Nature Biotechnol

      Volume: 25 Pages: 1315-1321

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion.2007

    • Author(s)
      Fujino H., H.Hiramatsu, A.Tsuchiya, A.Niwa, H.Noma, M.Shiota, K.Umeda, M.Yoshimoto, M.Ito, T.Heike, T.Nakahata
    • Journal Title

      Faseb J 21

      Pages: 3499-3510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.2007

    • Author(s)
      Ishikawa F, Niiro H, Iino T, Yoshida S, Saito N, 0nohara S, Miyamoto T, Minagawa H, Fujii SI, Shultz LD, Harada M, Akashi K.
    • Journal Title

      Blood

      Volume: 119 Pages: 3591-3660

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.2007

    • Author(s)
      Watanabe S, Terashima K, 0hta S, Horibata S, Yajima M, Shiozawa Y, Dewan MZ, Yu Z, Ito M, Morio T, Shimizu N, Honda M, Yamamoto N
    • Journal Title

      Blood

      Volume: 109 Pages: 212-218

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/gammacnull (NOG) mice.2007

    • Author(s)
      Suemizu H., M.Monnai, Y.Ohnishi, M.Ito, N.Tamaoki, M.Nakamura
    • Journal Title

      Int J Oncol 31

      Pages: 741-751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice.2007

    • Author(s)
      Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T
    • Journal Title

      Leukemia

      Volume: 21 Pages: 136-142

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/gammacnull(NOG) mice.2007

    • Author(s)
      Suemizu H, Monnai M, 0hnishi Y, Ito M, Tamaoki N, Nakamura M
    • Journal Title

      Int. J. Oncol.

      Volume: 31 Pages: 741-751

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.2007

    • Author(s)
      Watanabe S., K.Terashima, S.Ohta, S.Horibata, M.Yajima, Y.Shiozawa, M.Z.Dewan, Z.Yu, M.Ito, T.Morio, N.Shimizu, M.Honda, N.Yamamoto
    • Journal Title

      Blood 109

      Pages: 212-218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis.2006

    • Author(s)
      Nakamura T., Y.Miyakawa, A.Miyamura, A.Yamane, H.Suzuki, M.Ito, Y.Ohnishi, N.Ishiwata, Y.Ikeda, N.Tsuruzoe
    • Journal Title

      Blood 107

      Pages: 4300-4307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Development of human-human hybridoma from anti-Her-2 peptide-producing B cells in immunized NOG mouse.2006

    • Author(s)
      Kametani Y., M.Shiina, I.Katano, R.Ito, K.Ando, K.Toyama, H.Tsukamoto, T.Matsumura, Y.Saito, D.Ishikawa, T.Taki, M.Ito, K.Imai, Y.Tokuda, S.Kato, N.Tamaoki, S.Habu
    • Journal Title

      Exp Hematol 34

      Pages: 1239-1247

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Clonal analysis of thymus-repopulating cells presents direct evidence for self-renewal division of human hematopoietic stem cells.2006

    • Author(s)
      Yahata T., S.Yumino, Y.Seng, H.Miyatake, T.Uno, Y.Muguruma, M.Ito, H.Miyoshi, S.Kato, T.Hotta, K.Ando
    • Journal Title

      Blood 108

      Pages: 2446-2454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment.2006

    • Author(s)
      Muguruma Y., T.Yahata, H.Miyatake, T.Sato, T.Uno, J.Itoh, S.Kato, M.Ito, T.Hotta, K.Ando
    • Journal Title

      Blood 107

      Pages: 1878-1887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Journal Article] Independent accumulations of tau and amyloid β-protein in the human entorhinal cortex.2005

    • Author(s)
      Katsuno T, Morishima-Kawashima M, Saito Y, Yamanouchi H, Ishiura S, Murayama S, Ihara Y
    • Journal Title

      Neurology 64

      Pages: 687-692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12210005
  • [Journal Article] Characterization of SSU and LSU rRNA genes of three Trypanosoma(Herpetosoma)grosi isolates maintained in Mongolian jirds2005

    • Author(s)
      Sato, H., A.Osanai, H.Kamiya, Y.Obara, W.Jiang, Q.Zhen, J.Chai, Y.Une, M.Ito
    • Journal Title

      Parasitology 130

      Pages: 157-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive nuclear factor-kappaB activity in unconditioned NOD/SCID/gammac(null)mice2005

    • Author(s)
      Dewan, M.Z., M.Watanabe, S.Ahmed, K.Terashima, S.Horiuchi, T.Sata, M.Honda, M.Ito, T.Watanabe, R.Horie, N.Yamamoto
    • Journal Title

      Cancer Sci 96

      Pages: 466-473

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads.2005

    • Author(s)
      Miyasaka T, Watanabe A, Saito Y, Murayama S, Mann DMA, Yamazaki M, Ravid R, Morishima-Kawashima M, Nagashima K, Ihara Y
    • Journal Title

      J Neuropathol Exp Neurol 64

      Pages: 665-674

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12210005
  • [Journal Article] Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice2005

    • Author(s)
      Matsuura-Sawada, R., T.Murakami, Y.Ozawa, H.Nabeshima, J.Akahira, Y.Sato, Y.Koyanagi, M.Ito, Y.Terada, K.Okamura
    • Journal Title

      Hum Reprod 20

      Pages: 1477-1484

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Epidemiology of Helicobacter infection in wild rodents in the Xinjiang-Uygur autonomous region of China2004

    • Author(s)
      Goto, K., W.Jiang, Q.Zheng, Y.Oku, H.Kamiya, T.Itoh, M.Ito
    • Journal Title

      Curr Microbiol 49

      Pages: 221-223

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] T cell-dependent elimination of dividing Trypanosoma grosi from the bloodstream of Mongolian jirds2004

    • Author(s)
      Sato, H., K.Ishita, A.Osanai, M.Yagisawa, H.Kamiya, M.Ito
    • Journal Title

      Parasitology 128

      Pages: 295-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Gem GTPase and tau : morphological changes induced by Gem GTPase in CHO cells are antagonized by tau.2004

    • Author(s)
      Oyama F, Kotliarova S, Harada A, Ito M, Miyazaki H, Ueyama Y, Hirokawa N, Nukina N, Ihara Y
    • Journal Title

      J Biol Chem 279

      Pages: 27272-27277

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12210005
  • [Journal Article] Establishment of a new model of human multiple myeloma using NOD/SCID/gammac(null)(NOG)mice2004

    • Author(s)
      Miyakawa, Y., Y.Ohnishi, M.Tomisawa, M.Monnai, K.Kohmura, Y.Ueyama, M.Ito, Y.Ikeda, M.Kizaki, M.Nakamura
    • Journal Title

      Biochem Biophys Res Commun 313

      Pages: 258-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body2004

    • Author(s)
      Kambe, N., H.Hiramatsu, M.Shimonaka, H.Fujino, R.Nishikomori, T.Heike, M.Ito, K.Kobayashi, Y.Ueyama, N.Matsuyoshi, Y.Miyachi, T.Nakahata
    • Journal Title

      Blood 103

      Pages: 860-867

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Competitive repopulation assay of two gene-marked cord blood units in NOD/SCID/gammac(null)mice2004

    • Author(s)
      Yahata, T., K.Ando, H.Miyatake, T.Uno, T.Sato, M.Ito, S.Kato, T.Hotta.
    • Journal Title

      Mol Ther 10

      Pages: 882-891

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice2004

    • Author(s)
      Dewan, M.Z., M.Watanabe, K.Terashima, M.Aoki, T.Sata, M.Honda, M.Ito, S.Yamaoka, T.Watanabe, R.Horie, N.Yamamoto
    • Journal Title

      Cancer Sci 95

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Persistent infection of Mongolian jirds with a non-pathogenic trypanosome, Trypanosoma(Herpetosoma)grosi2003

    • Author(s)
      Sato, H., K.Ishita, K.Matsuo, T.Inaba, H.Kamiya, M.Ito
    • Journal Title

      Parasitology 127

      Pages: 357-363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null)mice : suppression by an inhibitor against NF-kappaB2003

    • Author(s)
      Dewan, M.Z., K.Terashima, M.Taruishi, H.Hasegawa, M.Ito, Y.Tanaka, N.Mori, T.Sata, Y.Koyanagi, M.Maeda, Y.Kubuki, A.Okayama, M.Fujii, N.Yamamoto
    • Journal Title

      J Virol 77

      Pages: 5286-5294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Fate of neural stem cells grafted into injured inner ears of mice2003

    • Author(s)
      Tateya, I., T.Nakagawa, F.Iguchi, T.S., Kim, T.Endo, S.Yamada, R.Kageyama, Y.Naito, J.Ito.
    • Journal Title

      Neuroreport 14

      Pages: 1677-1681

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null)(NOG)mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells2003

    • Author(s)
      Matsumura, T., Y.Kametani, K.Ando, Y.Hirano, I.Katano, R.Ito, M.Shiina, H.Tsukamoto, Y.Saito, Y.Tokuda, S.Kato, M.Ito, K.Motoyoshi, S.Habu.
    • Journal Title

      Exp Hematol 31

      Pages: 789-797

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Complete reconstitution of Human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model2003

    • Author(s)
      Hiramatsu, H., R.Nishikomori, T.Heike, M.Ito, K.Kobayashi, K.Katamura, T.Nakahata
    • Journal Title

      Blood 102

      Pages: 873-880

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Disruption of imprinting in cloned mouse fetuses from embryonic stem cells2003

    • Author(s)
      Ogawa, H., Y.Ono, N.Shimozawa, Y.Sotomaru, Y.Katsuzawa, H.Hiura, M.Ito, T.Kono.
    • Journal Title

      Reproduction 126

      Pages: 549-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Journal Article] Meriones meridianus and Lagurus lagurus as alternative definitive hosts of Echinococcus multilocularis and E.granulosus2002

    • Author(s)
      Oku, Y., J.Wei, J.J.Chai, I.Osman, L.F.Liao, M.Asakawa, K.Hagiwara, K.Kobayashi, M.Ito
    • Journal Title

      Exp Anim 51

      Pages: 27-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Seroprevalence of Borna disease virus in domestic animals in Xinjiang, China2001

    • Author(s)
      Hagiwara, K., M.Asakawa, L.Liao, W.Jiang, S.Yan, J.Chai, Y.Oku, K.Ikuta, M.Ito
    • Journal Title

      Vet Microbiol 80

      Pages: 383-389

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Journal Article] Mutant-presenilin 2-transgenic mice : A large increase in the levels of Aβ42 is presumably associated with the low-density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin.2000

    • Author(s)
      Sawamura N, Morishima-Kawashima M, Waki H, Kobayashi K, Kuramochi T, Ito M, Oyama F, Ando S, Ihara Y
    • Journal Title

      J Biol Chem 275

      Pages: 27901-27908

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12210005
  • [Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse

    • Author(s)
      Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K
    • Journal Title

      Int.Immunol.

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Patent] Methods of constructing mouse suitable for the take, differentiation and proliferation of heterogenous cells, mouse constructed by the method and use of the mouse2007

    • Inventor(s)
      M, Ito, et.al.
    • Industrial Property Rights Holder
      Central Institute for Experimental Animals
    • Acquisition Date
      2007-10-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Patent] Methods of producing a mouse suitable for the engraftment, differentiation and proliferation of heterologous cells, mouse produced by this method and use of the mouse2006

    • Inventor(s)
      M, Ito, et.al.
    • Industrial Property Rights Holder
      Central Institute for Experimental Animals
    • Acquisition Date
      2006-12-05
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Patent] 異種細胞の生着、分化および増殖に適したマウスの作出方法、該方法により作出されたマウスならびにそのマウスの用途2005

    • Inventor(s)
      伊藤守, 他9名
    • Industrial Property Rights Holder
      財団法人実験動物中央研究所
    • Acquisition Date
      2005-11-16
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] Dose Dependent Effects of Human IL-2 on the reconstitution and Function of Human Regulatory T cells in Humanized Mice.2013

    • Author(s)
      Li, Y., Katano, I., Dusseaux, M., Pang, Y., Court, N. Rogge, L., Ito, M., Strick-Marchand, H. and Di Santo, J.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Predominant development of mature and functional human NK Cells in a novel human IL-2 producing transgenic NOD-scid,IL-2Rg KO (NOG) mouse.2013

    • Author(s)
      Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスを用いたヒトアレルギーモデルの開発2013

    • Author(s)
      伊藤亮治
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      茨城・筑波国際会議場
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Assessment of the Pathogenic Potential of Simian Retrovirus Type 4 in Humanized Mice.2013

    • Author(s)
      Kobayashi, T., Sato, K., Misawa, N., Yoshikawa, R., Takeuchi, J., Kanemura, Y., Fukuhara, M., Okamoto, M., Miyazawa, T., Yasunaga, J., Matsuoka, M., Aihara, K., An, D.S., Ito, M. and Koyanagi, Y.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Leukemic Modeling in Humanized Mice. 4th International Workshop of Humanized Mice.2013

    • Author(s)
      Kato, I., Morita, M., Nishinaka, Y., Hashimoto, Y., Amano, N., Watanabe, A., Saida, S., Niwa, A., Saito, M., Umeda, K., Hiramatsu, H., Watanabe, K-I., Ito, M., Adachi, S., Heike, T. and Nakahata, T.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Pathology of cutaneous xeno-GVHD in human CD4 T cell transplanted NOG mice.2013

    • Author(s)
      伊藤亮治, 片野いくみ, 高橋武司, 伊藤守
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      千葉・幕張メッセ
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Human mast cell mediated allergic responses in humanized NOG mouse expressing human IL-3 and GM-CSF.2013

    • Author(s)
      Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Mamoru Ito
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Functional NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice.2013

    • Author(s)
      Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
    • Organizer
      第15回国際免疫学会
    • Place of Presentation
      ミラノ・イタリア
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Retrogenic expression of human TCR in HLA-DR4 transgenic NOG mice2013

    • Author(s)
      高橋武司, 片野いくみ, 伊藤亮治, 伊藤守
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      千葉・幕張メッセ
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013

    • Author(s)
      Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
    • Organizer
      第15回国際免疫学会
    • Place of Presentation
      ミラノ・イタリア
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Severely Immunodeficient Mice Improved in CIEA for Humanized Mouse Models.2013

    • Author(s)
      Ito, M.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Invited
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Characterization of human Eosinophil in HSC-transferred NOG-human IL-5 transgenic mice2013

    • Author(s)
      片野いくみ, 伊藤亮治, 高橋武司, 伊藤守
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      千葉・幕張メッセ
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Antibody-Secreting B Cells are Directly Developed from Transitional B cells of Humanized NOG Mice.2013

    • Author(s)
      Kametani, Y., Mori, S., Shimada, S., Oshima, S., Aokawa, J., Okada, Y., Goto, Y., Tsuda, B., Yahata, T., Ito, R., Katano, I., Suemizu, H., Ito, M., Habu, S. and Ando, K.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] IgE-mediated allergic responses in human mast cells in humanized NOG mice expressing human IL-3 and GM-CSF.2013

    • Author(s)
      Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Satoshi Nunomura, Chisei Ra, Akio Mori, Sadakazu Aiso, Mamoru Ito
    • Organizer
      第15回国際免疫学会
    • Place of Presentation
      ミラノ・イタリア
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013

    • Author(s)
      Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Restriction and Diversification of HIV-1 Mediated by APOBEC3-Induced G-to-A Mutation in Humanized Mouse Model. 4th International Workshop of Humanized Mice.2013

    • Author(s)
      Sato, K., Takeuchi, J., Misawa, N., Izumi, T., Kobayashi, T., Kimuram Y., Iwami, S., Takaori-Kondo, A., Hu, W-S., Aihara, K., Ito, M., An, D.S., Pathakm, V. and Koyanagi, Y.
    • Organizer
      第4回国際ヒト化マウスワークショップ
    • Place of Presentation
      ソウル
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Immunodeficient mice and humanized mouse models2012

    • Author(s)
      Mamoru Ito
    • Organizer
      The 2012 Spring conference of the Korea Association of Immunologist
    • Place of Presentation
      Soul
    • Invited
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスを用いたヒトアレルギーモデルの確立2012

    • Author(s)
      伊藤亮治
    • Organizer
      第62回日本アレルギー学会秋季学術大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Development of humanized mice model2012

    • Author(s)
      Mamoru Ito
    • Organizer
      1st Samsung Humanized Mice Workshop
    • Place of Presentation
      Soul
    • Invited
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Functional maturation of human myeloid cells in NOG transgenic humanized mouse strain expressing human IL-3 and GM-CSF2012

    • Author(s)
      Ito R.
    • Organizer
      第41回日本免疫学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスにおけるヒトミエロイド系細胞の分化亢進2012

    • Author(s)
      伊藤亮治
    • Organizer
      第59回日本実験動物学会総会
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Development of NOG mouse based immunodeficient mice in CIEA2011

    • Author(s)
      Ito, M.
    • Organizer
      3^<rd> International Workshop of Humanized Mice
    • Place of Presentation
      Pittsburgh, USA
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] A novel humanized mouse model : improvement of human myelopoiesisin IL-3/GM-CSF transgenic NOG mice reconstituted with human hematopoietic stem cells2011

    • Author(s)
      伊藤亮治
    • Organizer
      第40回日本免疫学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒト化マウスーその限界と今後の展望2011

    • Author(s)
      伊藤守
    • Organizer
      第58回実験動物学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] 異種移植研究への応用に期待がかかるヒト化動物モデルの開発2011

    • Author(s)
      伊藤守
    • Organizer
      第14回日本異種移植研究会
    • Place of Presentation
      広島
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Xeno-GVHD occurred in NOG mice after transfer of CD4 and CD8 T cells human PBMC.2010

    • Author(s)
      Ito, R
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] NOGマウスを用いたxeno-GVHD抑制機構の解明2010

    • Author(s)
      伊藤亮治
    • Organizer
      第57回日本実験動物学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] Interferon-gamma produced by IKDC has a crucial role in suppression of xeno-GVHD in NOG mice.2010

    • Author(s)
      Ito, R
    • Organizer
      11th International Symposium on Dendritic Cells
    • Place of Presentation
      Lugano, Switzerland
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/gamma c^<null> (NOG)-HLA transgenic mice.2010

    • Author(s)
      Takahashi T, Suzuki M, Katano I, Ito R, Ishii N, Ito M, Sugamura K.
    • Organizer
      国際免疫学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] Super immunodeficient NOG mice for generating humanized mice.2010

    • Author(s)
      Ito, M.
    • Organizer
      KALAS International Symposium
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice)2009

    • Author(s)
      Takahashi T, Watanabe Y, Okajima A, Katano I, Ito R, Ito M, Ishii N, Tsuchiya S, Sugamura K
    • Organizer
      2nd international workshop on humanized mice
    • Place of Presentation
      オランダ・アムステルダム
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] Mouse models as "humanized mice"2009

    • Author(s)
      Ito M.
    • Organizer
      2^<nd> IWHM
    • Place of Presentation
      Holland
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] IFNg producing killer dendritic cells have a suppressive effect on Xeno-GVHD in NOG mice2009

    • Author(s)
      Ito, R.
    • Organizer
      第39日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] High sensitivity to xeno-GVHD in severely immunodeficient NOG mice attributable to dysfunction of dendritic cells2009

    • Author(s)
      Ito R
    • Organizer
      2^<nd> IWHM
    • Place of Presentation
      Holland
    • Year and Date
      2009-04-03
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] 「ヒト血液幹細胞移植マウスのウイルス病原性解析への利用」シンポジウム「ヒト化動物の現状と今後」2009

    • Author(s)
      小柳義夫、佐藤佳、伊藤守
    • Organizer
      第56回日本実験動物学会総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Takahashi T, Ito M, Sugamura K, et al
    • Organizer
      第2回ヒト化マウス国際ワークショップ
    • Place of Presentation
      オランダ
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] Mouse models as "humanized mice"2009

    • Author(s)
      Ito M.
    • Organizer
      2^<nd> International workshop of humanized mice
    • Place of Presentation
      Holland
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] High sensitivity to xeno-GVHD in severely immunodeficient NOG mice attributable to dysfunction of dendritic cells.2009

    • Author(s)
      Ito R, Ito M, et al
    • Organizer
      第2回ヒト化マウス国際ワークショップ
    • Place of Presentation
      オランダ
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] NOGマウスにおける樹状細胞の機能低下は高度 Xeno-GVHD発症の要因となる2008

    • Author(s)
      伊藤亮治
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-01
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] ヒト Delta-like 1トランスジェニックNOGマウスに発症する骨硬化はヒト造血系の再構築を抑制する2008

    • Author(s)
      伊藤亮治
    • Organizer
      第26回骨代謝学会
    • Place of Presentation
      大坂
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] NOGマウスにおける樹状細胞の機能低下は高度Xeno-GVHD発症の要因となる2008

    • Author(s)
      伊藤亮治
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] 重度免疫不全NOGマウスを用いた高GVHD感受性モデル2008

    • Author(s)
      伊藤亮治
    • Organizer
      日本実験動物科学技術2008
    • Place of Presentation
      仙台
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] Dendritic cells have a suppressive effect on xeno-GVHD in novel immunodeficient NOG mice2008

    • Author(s)
      伊藤亮治
    • Organizer
      第10回国際樹状細胞シンポジウム
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] ヒトDelta-like 1トランスジェニックNOGマウスに発症する骨硬化はヒト造血系の再構築を抑制する2008

    • Author(s)
      伊藤亮治
    • Organizer
      第26回骨代謝学会
    • Place of Presentation
      大坂
    • Data Source
      KAKENHI-PROJECT-18100005
  • [Presentation] NOGマウスの特性と再生治療研究への応用2004

    • Author(s)
      伊藤守
    • Organizer
      慶應大学COE再生公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2004-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Presentation] 複合免疫不全NOD/SCIFD/gcnull(NOG)マウスの開発とそのIn vivo実験医学への応用2004

    • Author(s)
      伊藤守
    • Organizer
      第37回日本無菌生物ノトバイオロジー学会
    • Place of Presentation
      横浜
    • Year and Date
      2004-01-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Presentation] Charateristics of NOG mice and their application to degenerative medicine2004

    • Author(s)
      Mamoru Ito
    • Organizer
      Keio University, COE synpodium
    • Place of Presentation
      Tokyo
    • Year and Date
      2004-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Presentation] Development of NOD/SCID/gcnull(NOG)mice and their application on in vivo medicine2004

    • Author(s)
      Mamoru Ito
    • Organizer
      The 37^<th> Annual Meeting of the Japanese Association of Germfree Life and Gnotobiology
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300147
  • [Presentation] epidemiology of Hilicobacter Infection in Wild Rodents in the Xinjinag-Uygur Autonomous region of China2003

    • Author(s)
      Kazuo Goto, W.Jiang, Q.Zheng, Y.Oku, H.Kamiya, T.Itch, M.Ito
    • Organizer
      XVIth International workshop gastrointestinal pathology and Helicobacter
    • Place of Presentation
      European Helicobacter study group
    • Year and Date
      2003-09-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13575039
  • [Presentation] Analysis of the human immunological system reconstructed in the hIL4-Tg NOG mouse.

    • Author(s)
      Kikuchi Y., Miyamoto A., Tsuda B., Katano I., Tokuda Y., Ito M., Kametani Y.
    • Organizer
      第43回日本免疫学会総会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] BRGヌードマウスの計画生産および特性データ

    • Author(s)
      水澤卓馬、小倉智幸、何裕遥、 上迫努、高橋利一、江藤智生、伊藤守、日置恭司
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] 重度免疫不全NOGヘアレスマウスの計画生産および特性データ

    • Author(s)
      何裕遥、 小倉智幸、水澤卓馬、上迫努、高橋利一、伊東一昭、堤秀樹、江藤智生、伊藤守、日置恭司
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] NOGマウス環境下で分化するtransitional B細胞の抗体産生細胞の解析

    • Author(s)
      小島美香、森修弥、嶋田新、大島志乃、伊藤守、鈴木隆二、安藤潔、亀谷美恵
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] APOBEC3F potently promotes HIV-1 diversification and evolution in humanized mouse model.

    • Author(s)
      Sato, K., Shibata, J., Izumi, T., Misawa, N., Kobayashi, T., Kimura, Y., Ito, M., Pathak, V. K., Koyanagi, Y.
    • Organizer
      Cold Spring Harbor Laboratory Meeting on Retroviruses
    • Place of Presentation
      New York, USA
    • Year and Date
      2014-05-19 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒト免疫系再構築マウスTransitional B細胞の抗体産生能解析

    • Author(s)
      4.小島美香、森修弥、大島志乃、伊藤守、安藤潔、亀谷美恵
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] ヒトIL=5遺伝子導入型NOGマウスのヒト好酸球分化能の解析

    • Author(s)
      片野いくみ、高橋武司、伊藤亮治、上迫努、何裕遥、小倉智幸、高橋利一、末水洋志、河上裕、伊藤守
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-22220007
  • [Presentation] TK-NOGマウスの計画生産および特性データ

    • Author(s)
      富山香代、小倉智幸、何裕遥、上迫努、高橋利一、伊藤守、日置恭司、末水洋志
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-22220007
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