INATOMI Jun 稲富淳

Researcher Number	00311960
Affiliation (based on the past Project Information) *help	2005: The University of Tokyo, Faculty of Medicine, Research Associate, 医学部附属病院, 助手 1999 – 2001: 杏林大学, 医学部, 助手 1999 – 2000: 杏林大学, 医学部・薬理学, 助手 1999: Kyorin University School of Medicine, Department of Pharmacology & Toxicology, Assistant
Review Section/Research Field	Principal Investigator General pharmacology / Kidney internal medicine Except Principal Investigator 応用薬理学・医療系薬学 / Pediatrics / Pediatrics / General pharmacology
Keywords	Principal Investigator knockout mouse / organic anion transporter3 / organic anion transporter2 / organic anion transporter1 / gene targeting / brain / liver / kidney / pharmacokinetics / drug transporter … More / organic anion transporter / gene targetting / 近位尿細管性アシドーシス / 遺伝子変異 / HCO_3^-共輸送 / Na^+ / 尿細管性アシドーシス … More Except Principal Investigator エストロン硫酸 / パラアミノ馬尿酸 / rBAT / BAT1 / HCO3^- cotransporter / 近位尿細管性アシドーシス / SLC4A4 / Na^+ / オクラトキシンA / renoprotective medicine / Th1 action / angiotensin type II receptor blocker / 腎機能 / ARB / アンギオテンシンII受容体 / アンギオテンシンII受容体拮抗薬 / 腎機能保護 / Th1作用 / アンギオテンシンII受容体拮抗 / environmental factor / genetic factor / renal stones / Sodium-bicarbonate cotransporter / Cystinuria / Proximal tubular acidosis / rBATl / BATl / 近位尿再管性アシドーシス / ナトリウム / 環境因子 / 遺伝因子 / 尿路結石 / 重炭酸イオン共輸送体 / Na+ / シスチン尿症 / Sertoli cell / Epididymis / SNP / Uric acid / Idopathic renal hypouricemia / Carnitine / Cation transporter / Anion transporter / デヒドロエピアンドロステロン硫酸 / エクソン / イントロン / 一塩基変異遺伝子多型 / 突発性腎性低尿酸血症 / 胎盤 / セルトリ細胞 / 精巣上体 / 一塩基変異遺伝子 / 尿酸 / 特発性腎性低尿酸血症 / カルニチン / カチオントランスポーター / アニオントランスポーター / L-Dopa / Triiodethyronie / Aromatic amino acid / Heterocllimer / Associating protein / LAT family / Organic anion transporter / Drug transporter / システイン抱合体 / サリチル酸 / OATファミリー / 有機陰イオントランスポーター(OAT) / メチル水銀システイン抱合体 / 血液脳関門 / L-ドーパ / トリヨードサイロニン / 芳香族アミノ酸 / ヘテロダイマー / 補助因子 / LATファミリー / 有機陰イオントランスポーター / 薬物トランスポーター / nonsense mutation / missense mutation / glaucoma / short stature / proximal renal tubular acidosis / 帯状角膜変性症 / 白内障 / SLC4AC / ナンセンス変異 / ミスセンス変異 / 緑内障 / 低身長 / HCO^3^- cotransporter / multispecific substrate recognition / carnitine transporter / organic cation transporter / ochratoxin A / estron sulfate / para-amino hippurate / organic anion transporter / organic anion / 薬物輸送 / ジカルボン酸トランスポーター / トランスポーター / ジカルボン酸 / 近位尿細管中間部 / 多選択性基質認識 / カルニチントランスポーター / 有機カチオントランスポーター / 有機アニオントランスポーター / 有機アニオン Less

To clarify the mechanism of Th1 suppression to protect renal function by angiotensin II receptor blocker
- Principal Investigator
  
  IGARASHI Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern Asia
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphism
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Na^+/HCO_3^-共輸送体遺伝子変異と近位尿細管性アシドーシスとの関連性の解明Principal Investigator
- Principal Investigator
  
  稲冨淳
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
FUNCTIONAL ANALYSIS OF THE ANIONIC DRUG TRANSPORTERS USING KNOCKOUT MICEPrincipal Investigator
- Principal Investigator
  
  INATOMI Jun, 車碩鎬
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Identification of diseasen causing gene in patients with permanent isolated proximal renal tubular acidosis with ocular abnormalities
- Principal Investigator
  
  IGARASHI Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Molecular mechanisms of drug transport across cell membrane
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Molecular cloning and functional expression of kidney-specific organic anionic drug transporters
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University School of Medicine

All 2005 2004 2002 2001

All Journal Article

[Journal Article] A familial case of muticystic dysplastic kidney.2005
- Author(s)
  Sekine T, Yanagisawa A, Harita Y, Inatomi J, Igarashi T
- Journal Title
  
  Pediatr Nephrol 20・4
  
  Pages: 1245-1248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591010
[Journal Article] Functional analysis of NBC1 mutants associated with proximal tubular acidosis and ocular abnormalities.2005
- Author(s)
  Horita S, Yamada H, Inatomi J, Moriyama N, Sekine T, Igarashi T, Endo Y, Dasouki M, Ekim M, Al-Gazali L, Shimada M, Seki G, Fujita T
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 2270-2278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591010
[Journal Article] A familial case of muticystic dysplastic kidney.2005
- Author(s)
  Sekine T, Namai Y, Yanagisawa A, Harita Y, Inatomi J, Igarashi T
- Journal Title
  
  Pediatr Nephrol 20・4
  
  Pages: 1245-1248
- Data Source
  KAKENHI-PROJECT-16591010
[Journal Article] A familial case of multicystic dysplastic kidney.2005
- Author(s)
  Sekine T, Namai Y, Yanagisawa A, Shirahama H, Tashiro Y, Terahara M, Nagata M, Harita Y, Fukuoka U, Inatomi J, Igarashi T
- Journal Title
  
  Pediatr Nephrol 20
  
  Pages: 1245-1248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591010
[Journal Article] Mutation and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004
- Author(s)
  Inatomi J, Horita S, Braverman N, Sekine T, Yamada H, Suzuki Y, Kawahara K, Moriyama N, Kudo A, Kawakami H, Ahimadzu M, Endou H, Fujita T, Seki G, Igarashi T
- Journal Title
  
  Pfluegers Arch-Eur.J.Physiol. 448
  
  Pages: 438-444
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004
- Author(s)
  Inatomi J, Igarashi T, et al.
- Journal Title
  
  Pfluger Arch-Eur J Physiol 448(2)
  
  Pages: 438-444
- Data Source
  KAKENHI-PROJECT-16591010
[Journal Article] Identification of novel Na+-independent acidic amino acid transporter with structural similarity to the member of heterodimeric amino acid transporter family associated with unknown heavy chains.2002
- Author(s)
  Matsuo H, Kanai Y, Kim JY, Chairungdua A, Kim DK, Inatomi J, Shigeta, Y, Ishimine H, Chekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H.
- Journal Title
  
  J Biol Chem. 277
  
  Pages: 21017-21026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain.2001
- Author(s)
  Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H
- Journal Title
  
  J Biol Chem. 276
  
  Pages: 49390-49399
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human cystine/glutamate transporter : cDNA cloning and upregulation by oxidative stress in glioma cells.2001
- Author(s)
  Kim JY, Kanai Y, Chairoungdua A, Cha SH, Matsuo H, Kim DK, Inatomi J, Sawa. H, Ida Y, Endou H.
- Journal Title
  
  Biochem Biopys Acta 1512
  
  Pages: 335-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004

1. KANAI Yoshikatsu (60204533)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. HOSOYAMADA Makoto (00291659)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. ENDOU Hitoshi (20101115)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
4. TAKEDA Michio (40255401)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. KIM Do Kyung (40327474)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
6. SEKINE Takashi (50255402)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
7. CHA Seok ho (50276200)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. IGARASHI Takashi (70151256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. ANZAI Naohiko (70276054)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. IRIBE Yuji (20348618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRATA Taku (60372918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 楯直子 (00201955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

INATOMI Jun 稲富 淳

Research Projects

Research Products

Co-Researchers

To clarify the mechanism of Th1 suppression to protect renal function by angiotensin II receptor blocker

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern Asia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Na^+/HCO_3^-共輸送体遺伝子変異と近位尿細管性アシドーシスとの関連性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FUNCTIONAL ANALYSIS OF THE ANIONIC DRUG TRANSPORTERS USING KNOCKOUT MICEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of diseasen causing gene in patients with permanent isolated proximal renal tubular acidosis with ocular abnormalities

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of drug transport across cell membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular cloning and functional expression of kidney-specific organic anionic drug transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A familial case of muticystic dysplastic kidney.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Functional analysis of NBC1 mutants associated with proximal tubular acidosis and ocular abnormalities.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] A familial case of muticystic dysplastic kidney.2005

Author(s)

Journal Title

Data Source

[Journal Article] A familial case of multicystic dysplastic kidney.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Mutation and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004

Author(s)

Journal Title

Data Source

[Journal Article] Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004

Author(s)

Journal Title

Data Source

[Journal Article] Identification of novel Na+-independent acidic amino acid transporter with structural similarity to the member of heterodimeric amino acid transporter family associated with unknown heavy chains.2002

INATOMI Jun 稲富淳