OHUCHI Kazuo 大内和雄

… Alternative Names

OUTI Kazuo 大内和雄

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Researcher Number	20006357
External Links
Affiliation (based on the past Project Information) *help	2009: 安田女大, 薬学部, 教授 1999 – 2005: 東北大学, 大学院・薬学研究科, 教授 1995 – 1998: 東北大学, 薬学部, 教授 1989 – 1993: Tohoku University, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1991: 東北大, 薬学部, 教授 … More 1991: 東北大学薬学部, 病態生化学, 教授 1990: 東北大学, 薬学部・病態生化学, 教授 1987 – 1988: 東北大学, 薬学部, 助教授 1986: 東北大, 薬学部, 助教授 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / 医薬分子機能学 Except Principal Investigator Biological pharmacy / General pharmacology / Respiratory organ internal medicine / Biological pharmacy / 応用薬理学・医療系薬学 / Circulatory organs internal medicine / Biological Sciences
Keywords	Principal Investigator ICAM-1 / マクロファージ / 空気嚢型炎症モデル / 気道上皮細胞 / 42 MAP kinase / p44 / マスト細胞 / ヒスタミン / ステロイド性抗炎症薬 / 発がん促進物質 … More / Vascular permeability / Glucocorticoid / ザイモサン炎症 / 血管透過性反応 / 抗炎症薬 / グルココルチコイド / E-cadherin / histamine / Eosinophils / STAT1 / 好酸球 / p38 MAP kinase / E6123 / prostaglandin E2 / indomethacin / thapsigargin / cDNA / ribonuclease / eosinophil cationic protein / major basic protein / 好酸球顆粒蛋白質 / アラキドン酸代謝 / ヒスチジン脱炭酸酵素 / ケモカイン / 血小板活性化因子 / 血管内皮細胞 / 好中球 / 肥満細胞 / プロスタグランディン / アラキドン酸 / Chemotactic factor / Peptide-leukotriene / Neutrophil infiltration / プロスタグランジンロイコトリエン / 好中球遊走因子 / ペプチドロイコトリエン / 好中球浸潤 / 血管透過性亢進 / Footpad edema / Prostaglandin / Arachidonic acid / Phospholipase / Anti-inflammatory drugs / Lipocortin / インドメタシン / プロスタグランジン / 抗炎症ステロイド / グリココルチコイド / 足浮腫反応 / ホスホリパ-ゼ / リポコルチン / differentiation of eosinophil / HDAC inhibitor / eosinophil granule protein / Bronchial epithelial cells / NF-κB / RNase A / 顆粒蛋白質 / Cycline-dependent kinase / Interferon-gamma / Epitherial cells / Bactericidal activity / RNase activity / Eosinophil-associated rebonuclease / ヒストン脱アセチル化酵素阻害薬 / HL-60 clone 15 / BEAS-2B / NCI-H292 / 12-O-tetradecanoylphorbol 13-acetate / Adherence junction / 分化・増殖 / アデノウイルス / E-カドヘリン / E-Cadherin / 好酸球分化 / HDAC阻害薬 / Steroid anti-inflammatory drug / Epithelial cells / Macrophages / Mast cells / Neutrophils / macrophage inflammatory protein-2 / interleukin-4 / cyclooxygenase-2 / 44 MAP kinase / p42 / デキサメサゾン / アポトーシス / p38MAP kinase / SK & F 98625 / macrophage / tumor necrosis factor-alpha / platelet-activating factor / SK&F98625 / prostaglandin E_2 / L-652,731 / SK&F 98625 / tumor necrosis factor-α / cytotoxicity / eosinophil granule proteins / rat eosinophils / ラットMBP cDNA / ラットMBP / eosinophil-derived neurotoxin / ラット好酸球 / 細胞傷害性 / スタウロスポリン / オカダ酸 / プロスタグランディンE_2 / gossypol / staurosparine / okadaic acid / teleacrdin / TPA / サイクロオキシゲナーゼ阻害剤 / アレルギー反応 / プロスタグランディン【E_2】 / 再燃 / 炎症反応 / RBL-2H3 / プロテアソーム阻害薬 / グルココルチコイド受容体 / MAP kinase阻害薬 / キナーゼ阻害薬 / dexamethasone / KSR / p44-42 MAP kinase / HSP90 / LAT / Spred-1 / Raf-1 / 脂質ラフト / H_2受容体 / 白血球浸潤 / 血管透過性 / アレルギー性空気嚢型炎症 / 80 / compound48 / 皮内反応 / glucocorticoid / cAMP-dependent protein kinase / tyrosine kinase / protein kinase C / MIP-2 / LDNCF-2 / 浸潤白血球 / 接着分子 / 走化性因子 / 細胞遊走 / タンパク質合成 / 脱顆粒反応 / マクロファ-ジ … More Except Principal Investigator ヒスタミン / c-Jun N-terminal kinase / Raf-1 / 血小板活性化因子 / Histamine / Vascular endothelial growth factor / phosphodiesterase IV inhibitor / Endostatin / Angiopoietin-2 / Angiopoietin-1 / p38 MAP kinase / phosphatidylinositol 3-kinase / 炎症 / 測定法 / トロンボキサン / プロスタサイクリン / 血管新生 / 血管内皮増殖因子 / MAP kinase / ヒスチジン脱炭酸酵素 / 病態 / 肥満細胞 / ステロイド性抗炎症薬 / major basic protein / ラット好酸球 / 血管内皮細胞 / ミクロチスチン / オカダ酸クラス発がんプロモ-タ- / オカダ酸 / Granulation tissue / Angiogenesis / RAW264 / prostaglandin E2 / histamine / endostatin / angiopoietin-1 / 肉芽組織 / interleukin 4 / steroidal anti-inflammatory drug / mast cells / wortmannin / インターロイキン-4 / MAPキナーゼ / LTB_4 / 11beta-PGF_<2alpha> / LC-MS / leukotriene (LT) / 8-isoprostane / cyclooxygenase (COX) / thromboxane / prostaglandin / リポキシゲナーゼ / イムノアッセイ / MS / GC / シクロオキシゲナーゼ / ロイコトリエン / プロスタグランジン / Measurement / Inflammation / Toxemia of pregnancy / Hypertension / 2, 3-dinor-6-keto-prostaglandin F_1alpha / 11-dehydro-thromboxane B_2 / Thromboxane A_2 / Prostacyclin / 6,15-diketo-13,14 dihydro PGF_1α / 2,3-dinor 6-keto PGF_1α / EIA法 / RIA法 / 6,15-diketo-13,14dehydro PGF_1α / 2,3-dinor-b-keto PGF_1α / 11-dehydro-TXB_2 / プロスタサイクリン(PGI_2) / トロンボキサン(TXA_2) / 妊娠中毒症 / 高血圧 / 2,3-ジノル-6-ケト-PGF1α / 11-デヒドロ-トロンボキサンB2 / アレルギー / p38MAP kinase / p42MAP kinase / p44 / JAK2 / Vav / Btk / PI3-kinase / マスト細胞 / WHI-P131 / 骨髄由来マスト細胞 / Phosphatydilinositol 3-kinase / Gab2 / 脱顆粒反応 / JAK3 / RBL-2H3細胞 / ノックアウトマウス / H2受容体 / H1受容体 / 薬物作用 / 医療薬学 / 細胞・分子薬学 / 細胞内情報伝達 / 細胞間情報伝達 / 神経・免疫・内分泌相関 / 気管支喘息 / 胃潰瘍 / 中枢ヒスタミン神経系 / ヒスタミン代謝酵素 / ヒスタミン受容体 / dexamethasone / interleukin 5 / ラット好中球 / 骨髄細胞 / アポトーシス / ラットMBP cDNA / ラットMBP抗体 / 好酸球増多症 / 鼻粘膜血管内皮細胞 / NF-κB / IFN-γ / TPA / ICAM-1 / 気道上皮細胞 / 接着 / 細胞遊走 / ヒスタミン産生増大因子II / ヒスタミン産生増大因子I / アレルギ-性炎症 / プロテインキナ-ゼC / TRE / JE遺伝子 / アラキドン酸 / プロティンフォスファタ-ゼ / CNーTPBP / protein kinase C / プロスタグランジンE_2 / 蛋白質脱リン酸化酵素2A Less

細胞内外の酸性度変化による炎症細胞の活性化機構とその制御Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Yasuda Women's University
ステロイド感受性低下を改善するための標的分子の同定と創薬理論の構築Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Induction and termination of angiogenesis by regulation of angiogenesis-related factor production
- Principal Investigator
  
  HIRASAWA Noriyasu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
脂質ラフト形成を制御する機能蛋白質の探索Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Mechanism of tissue injury, repair and regeneration in inflammation, and regulation of remodelingPrincipal Investigator
- Principal Investigator
  
  OHUCHI Kazuo
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
サイトカインによるマスト細胞の機能修飾とその制御についての研究
- Principal Investigator
  
  平澤典保
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
ヒスチジン脱炭酸酵素欠損マウスを用いたアレルギー炎症におけるヒスタミンの役割解析Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
特定領域研究(B)「遺伝子改変動物を用いたヒスタミンの新規機能の発見」申請準備
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Analysis of roles of MAP kinase in inflammation and establishment of the target for development of a new anti-inflammatory drugPrincipal Investigator
- Principal Investigator
  
  OHUCHI Kazuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
『国際ヒスタミン・シンポジウム』の開催準備
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
加齢病態・疾病発病に関わる神経・免疫・内分泌相関の細胞分子・医療薬学的研究
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Studies on the COX inhibitor-induced PAF production and its pharmacological significancePrincipal Investigator
- Principal Investigator
  
  OHUCHI Kazuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Research into the effects of steroidal anti-inflammatory drugs on MAP kinase activation and cytokine production
- Principal Investigator
  
  HIRASAWA Noriyasu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
好酸球増多症におけるグルココルチコイドの作用点およびその機序の解析
- Principal Investigator
  
  無江季次
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sendai University
血小板活性化因子及び関連脂質による血管内皮細胞-顆粒球間認識の制御機構解析
- Principal Investigator
  
  渡邊雅子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
バイオテクノロジーを利用した好酸球顆粒蛋白質の大量調整と好酸球機能及び分化の解析
- Principal Investigator
  
  無江季次
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sendai University
炎症局所におけるケモカイン産生調節機序解明に関する研究Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Research into Cytotoxicity of Eosinophil Granule ProteinsPrincipal Investigator
- Principal Investigator
  
  OHUCHI Kazuo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tohoku University
Arachibonate cascade and physiological
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
血管内皮細胞による炎症性細胞の血管外遊走の調節機構の解明Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
顆粒球の血管内皮細胞認識と血管外遊走における血小板活性化因子の役割解析
- Principal Investigator
  
  渡邉雅子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
遅発型アレルギ-におけるヒスタミン放出に関与する新規サイトカインの同定と役割解析
- Principal Investigator
  
  平澤典保
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Standardization and problems to measure prostanoids in the biological fluid.
- Principal Investigator
  
  ABE Keishi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  TOHOKU UNIVERSITY
炎症局所における好中球浸潤のモデル化と血管内皮細胞と好中球の相互作用解析Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
発がん促進物質によるアラキドン酸代謝亢進機序解明に関する研究Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
発がんプロモ-ションの機構とその阻害
- Principal Investigator
  
  藤木博太
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
発がんプロモ-ションの機構とその阻害
- Principal Investigator
  
  藤木博太
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
発がん促進物質によるアラキドン酸代謝亢進機序解明に関する研究Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Mechanisms for anti-inflammatory actions of glucocorticoidPrincipal Investigator
- Principal Investigator
  
  OHUCHI Kazuo, 鶴藤丞
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU UNIVERSITY
発がん促進物質によるアラキドン酸代謝亢進機序解明に関する研究Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Comparison of anti-inflammatory activities between recombinant human lipocortin and glucocorticoid.Principal Investigator
- Principal Investigator
  
  OHUCHI Kazuo, 鶴藤丞
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU UNIVERSITY
再燃型炎症モデルの確立と,抗炎症薬スクリーニング系への活用に関する研究Principal Investigator
- Principal Investigator
  
  大内和雄
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University

All 2005 2004

All Journal Article

[Journal Article] Induction of nitric oxide production by the cytostatic macrolide apicularen a [2,4-heptadienamide, N-[(1E)-3-[(3S,5R,7R,9S)-3,4,5,6,7,8,9,10-octahydro-7,14 dihydroxy-1-oxo-5,9-epoxy-1H-2-benzoxacyclo dodecin-3-yl]-1 prope nyl]-, (2Z,4Z)-(9CI)] and possible role of nitric oxide in apicularen A-induced apoptosis in raw 264.7 cells.2005
- Author(s)
  J.Hong, A.Yokomakura, Y.Nakano, H.S.Ban, K.Ishihara, J.W.Ahn, O.P.Zee, K.Ohuchi
- Journal Title
  
  J.Pharmacol.Exp.Ther. 312
  
  Pages: 968-977
- Data Source
  KAKENHI-PROJECT-14370738
[Journal Article] Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-PI31and WHI-P154 in a Janus kinase 3-independent manner.2005
- Author(s)
  Linwong, W., Hirasawa, N., Aoyama, S., Hamada, H., Saito, T., Ohuchi, K.
- Journal Title
  
  Br.J.Pharmacol. 145
  
  Pages: 818-828
- Data Source
  KAKENHI-PROJECT-14370738
[Journal Article] プロスタグランジンの血管新生制御機構2005
- Author(s)
  平澤典保, 大内和雄
- Journal Title
  
  オレオサイエンス 5
  
  Pages: 65-71
- NAID
  10014305322
- Data Source
  KAKENHI-PROJECT-15390020
[Journal Article] Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils.2004
- Author(s)
  Ishihara, K., Hong, J., Zee, O.P., Ohuchi, K.
- Journal Title
  
  Br.J.Pharmacol. 142
  
  Pages: 1020-1030
- Data Source
  KAKENHI-PROJECT-14370738
[Journal Article] Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1.2004
- Author(s)
  Kamei, D., Hirasawa, N., Ohuchi, K.他14名
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 33684-33695
- Data Source
  KAKENHI-PROJECT-15390020

1. HIRASAWA Noriyasu (80181155)

# of Collaborated Projects: 13 results

# of Collaborated Products: 3 results
2. WATANABE Masako (90182948)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. MIZUGAKI Mitinao (60004595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YAMAMOTO Syuzo (50025607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MUROTA Seiitsu (50072989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ABE Keishi (60004777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KATORI Makoto (50050365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. WADA Yumiko (70167469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 藤木博太 (60124426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 深見泰夫 (00156746)

# of Collaborated Projects: 2 results

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11. 橋本祐一 (90164798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 野瀬清 (70012747)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 無江季次 (40004882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 渡邉建彦 (70028356)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 市川厚 (10025695)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 鶴藤丞 (40012596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. SHIMIZU Takao (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OMATA Ken (50194634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ISHIHARA Kenji (00312596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 石川隆俊 (30085633)

# of Collaborated Projects: 1 results

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21. 上村大輔 (00022731)

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22. 白土邦男 (80004761)

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23. 岡部進 (90012624)

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24. 坂田利家 (50037420)

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25. 野村靖幸 (00034041)

# of Collaborated Projects: 1 results

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26. 工藤一郎 (30134612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 堅田利昭 (10088859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 入村達郎 (80092146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 乾賢一 (70034030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 渡辺武 (40028684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 福井裕行 (90112052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 亀井千晃 (60116449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHUCHI Kazuo 大内 和雄

OUTI Kazuo 大内 和雄

Research Projects

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細胞内外の酸性度変化による炎症細胞の活性化機構とその制御Principal Investigator

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ステロイド感受性低下を改善するための標的分子の同定と創薬理論の構築Principal Investigator

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脂質ラフト形成を制御する機能蛋白質の探索Principal Investigator

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Mechanism of tissue injury, repair and regeneration in inflammation, and regulation of remodelingPrincipal Investigator

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ヒスチジン脱炭酸酵素欠損マウスを用いたアレルギー炎症におけるヒスタミンの役割解析Principal Investigator

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Analysis of roles of MAP kinase in inflammation and establishment of the target for development of a new anti-inflammatory drugPrincipal Investigator

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Studies on the COX inhibitor-induced PAF production and its pharmacological significancePrincipal Investigator

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OHUCHI Kazuo 大内和雄

OUTI Kazuo 大内和雄