Sabe Hisataka 佐邊壽孝

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… Alternative Names

SABE Hisataka 佐邊壽孝

左邊壽孝サベヒサタカ

佐邉壽孝サベヒサタカ

佐邊嘉孝サベヒサタカ

佐邉寿孝サベヒサタカ

佐辺寿孝サベヒサタカ

佐邊寿孝

佐邊壽孝

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Researcher Number	40187282
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 遺伝子病制御研究所, 客員教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 遺伝子病制御研究所, 客員教授 2018 – 2021: 北海道大学, 医学研究院, 教授 2015 – 2016: 北海道大学, 医学研究科, 教授 2012 – 2016: 北海道大学, 医学(系)研究科(研究院), 教授 2015: 北海道大学, 大学院医学系研究科, 教授 … More 2009 – 2012: Osaka Bioscience Institute, 大学院・医学研究科, 教授 2008: Osaka Bioscience Institute, 分子生物学部門, 研究部長 2007 – 2008: Osaka Bioscience Institute, Dept. of Molecular Biology, Dept. Head. 2007: Osaka Bioscience Institute, 分子生物学部門, 研究部長 2002 – 2006: (財)大阪バイオサイエンス研究所, 分子生物学部門, 研究部長 2004: (財)大阪バイオサイエンス研究所, 分子生物学部, 研究部長 2000 – 2001: (財)大阪バイオサイエンス研究所, 第1研究部, 研究部長 1999: 財団法人大阪バイオサイエンス研究所, 第1研究部, 研究部長 1998: (財)大阪バイオサイエンス研究所, 第1研究部, 研究部長 1995 – 1997: 京都大学, ウイルス研究所, 助教授 1995: 京都大学, ウィルス研究所, 助教授 1989: 京都大学, 遺伝子実験施設, 助手 1986 – 1988: 京都大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Cell biology / Cell biology / Basic Section 48040:Medical biochemistry-related / General medical chemistry / Biological Sciences / Biological Sciences Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Biological Sciences / Functional biochemistry / Structural biochemistry / Respiratory surgery / Radiation science
Keywords	Principal Investigator パキシリン / Arf6 / インテグリン / 細胞運動 / endocytosis / AMAP1 / paxillin / ARFGAP / 浸潤 / GEP100 … More / endosomal recycling / PAG3 / E-cadherin / 乳癌 / p130Cas / 細胞接着 / シグナル伝達 / AMAP2 / ARF6 / 癌悪性度進展 / p53 / Git1 / カドヘリン / Git2 / EGFR / ArfGEF / amphiphysin / ArfGAP / membrane trafficing / cell motile activity / 代謝 / 細胞浸潤 / TGFβ1 / EMT / 癌浸潤 / チロシンリン酸化 / 接触阻止 / PAGs / ARF / マクロファージ / 単球細胞 / ゴルジ装置 / 転移 / 癌細胞 / 膵癌 / AMAP１ / 腫瘍浸潤細胞 / 癌微小環境 / ケモカイン / 癌免疫回避 / ｐ53 / 上皮細胞 / ヒストン / 免疫回避 / 免疫監視 / 代謝変換 / ヒストン修飾 / CDH1 / 上皮性維持 / elF4A / G-quadruplex構造 / 翻訳制御 / mRNA翻訳 / KRAS / G-quadruplex / cancer malignancy / mRNA translation / eIF4A / neutrophil / invasion / GEF / ゴルジ体 / GPCR / Arf1 / 細胞運動方向持続性 / 細胞極性 / FEP100 / 好中球 / E3 ligase / non-ubiquitination / breast cancer / Cell invasion / Cell motility / E3因子 / 非標準的ユビキチン化 / cancer cell invasion / ArtGAP / Art6 / cell motility / cndosomal recycling / cell migration / 貪食作用 / 形質膜 / アクチン細胞骨格 / integrin / PAG / lyrosine phosphorylation / 上皮間充織形質転換 / 斉一単層形成能 / 蛋白質の細胞内動態 / アクチン骨格 / tyrosine phosphorylation / 細胞内配置 / Ａｒｆ6 / 活性酸素 / 細胞内器官配置 / 微小管 / Arf6経路 / 癌放射線抵抗性 / 変異p53 / 酸化的リン酸化 / ミトコンドリア / メバロン酸代謝活性 / β1 integrin / TP53 / 放射線抵抗性 / ILK / microRNA / 微小環境因子 / 癌浸潤転移 / Src / miRNA / エピゲノム変化 / ゲノム変異 / LPA / メバロン酸合成経路 / p53変異 / 薬剤耐性 / 癌間充識悪性 / 腎名細胞がん / Arf GTPases / Nck / 上皮細胞接着 / integrin β1 / EphA / VE-cadherin / 血管新生 / カドへリン / PRKD2 / インテグリンβ1 / GBP100 / 浸潤転移 / E-カドヘリン / 癌 / directional persistenc / cell polarity / Rac1 / Cdc42 / 運動極性 / c-Src / アクチン細胞骨格再構成 / membrane ruffle / RhoGAP / RhoA / プラコグロビン / βカテニン / Rho-family GTPases / 浸潤性 / F9 / P120 / カテニン / 細胞運動性 / インテグリンシグナル / タンパク質チロシンリン酸化 / 侵潤能 / 運動性 / 細胞内輸送 / 運動性制御 / Focal adhesion kinase / protein kinase B / Akt / Phosphatidyl 3 kinase / 単球 / 内皮細胞 / 細胞生存性 / 血管内皮細胞 / 蛋白質脱リン酸化酵素 / 蛋白質チロシンリン酸化 / 細胞基質接着 / 癌の転移性 / リン酸化 / 蛋白質分解 / マイトーシス / 細胞周期進行 / 細胞基質間接着 … More Except Principal Investigator 骨格筋 / Signal Transduction / ADF / AP-1 / REDUCTION / OXIDATIVE STRESS / REDOX / THIOREDOXIN / インテグリン / 細胞接着 / パキシリン / 運動能力 / 心筋 / ミトコンドリア / 5-ALA / 代謝 / スクシニルCoA / 心不全 / プロテオーム解析 / サルコペニア / 老化 / マイオカイン / ニュースレター / 計画研究 / ホームページ / 上皮管腔組織形成 / 管腔生物学 / 総括班 / 国際シンポジウム / 菅腔生物学 / 上皮菅腔組織形成 / 活性酸素 / 遊走 / 好中球 / Membrane-bound Cell Growth Factor / Laminin / Smooth Moscle Cells / Cadherin / PAxillin / Cell Adhesion / Extracellular Matrix / Integrin / HB-EGF / Rho / 細胞内骨格系 / シグナル伝達 / 膜結合型増殖因子 / ラミニン / 平滑筋細胞 / カドヘリン / 細胞外マトリックス / NFRB / Redox Regulation / チオレドキシン / レドックス制御 / プロモーター解析 / オキシゲン、バースト / 酸化ストレス / 白血病 / ノックアウトマウス / 胚形成 / Redox regulation / REDOX REGULATION / SIGNAL TRANSDUCTION / パーフォリン / 自然免疫 / HTLV-1 / 自己免疫 / レトロウイルス / エンハンサー / インターロイキン5 / インターロイキン2の受容体 / 人工突然変異 / リンフォカイン遺伝子 / 免疫グロブリン遺伝子 / IL-5遺伝子 / IL-4遺伝子 / 染色体マップ / トランスジェーニックマウス / IL-2リセプター / IL-4 / Bリンパ球の分化 / 抗体遺伝子D断片 / NK細胞 / トランスジュニックマウス / IL-2R / IL-2 / IgM^+IgG^+B細胞 / クラススイッチ / 骨髄細胞からのリンパ球への分化 / ヒト抗体V_H鎖遺伝子 / trans splicing / double isotype expression / transgenic mouse / integrase family / cDNAクローニング / DNA結合タンパク質 / 抗体遺伝子再構成 / 環状DNA / SーS組換え / ショウジョウバエ / リコンビナ-ゼ / ストロ-マ細胞 / 骨髄多分化能細胞 / VDJ組換 / Bリンパ球 / 予後 / Arf6 / GEP100 / p-EGFR / 胸部悪性腫瘍 / プラスチック検出器 / 非線形最適化 / 体幹部定位放射線照射 / プラスチック檢出器 / モンテカルロ法 / 電子線トラック解析 / 量子線シミュレーション / 低酸素細胞 / 胃癌 / 細胞遊走 / 生体の動き / 医学研究 / 動体追跡 / 放射線治療 / 細胞運動 / ARF GAP Less

スクシニルCoAによる心筋代謝機構の解明
- Principal Investigator
  
  高田真吾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hokusho University
Elucidation of the molecular basis of ARF6-AMAP1 pathway-dependent chemokine expression switch in response to the same stimulusPrincipal Investigator
- Principal Investigator
  
  Sabe Hisataka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Hokkaido University
Elucidation of the mechanism by which myokines regulate aging progress
- Principal Investigator
  
  Kinugawa Shintaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyushu University
The biological significance of the diversity of the epithelial cell integrityPrincipal Investigator
- Principal Investigator
  
  Sabe Hisataka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Hokkaido University
Mechansim by which Arf6 protein becomes overexpressed in cancer to promote malignancyPrincipal Investigator
- Principal Investigator
  
  Sabe Hisataka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
TP53 mutation drives cancer IR-resistance via the Arf6-based pathwayPrincipal Investigator
- Principal Investigator
  
  Sabe Hisataka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
An evaluation for identification of signaling pathway to make progress EMT of thoracic malignant tumor and evaluation of clinical specimens.
- Principal Investigator
  
  SHIMOKAWA Hidehiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Roles of ARFs in superoxide production and chemotaxis of neutrophil
- Principal Investigator
  
  MAZAKI Yuichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hokkaido University
  University of Occupational and Environmental Health, Japan
Luminal epithelium integrity and the EMTPrincipal Investigator
- Principal Investigator
  
  Sabe Hisataka
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure
- Principal Investigator
  
  Kikuchi Akira
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Research for Real-time Tracking Medical Science
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Invasiveness acquired during EMTPrincipal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
  Osaka Bioscience Institute
Arf GTPases in cell migration, invasion, and directional sensing and persistencyPrincipal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka Bioscience Institute
Mechanisms regulating cell adhesion activities in tumor progressionPrincipal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka Bioscience Institute
Roles played by Arf6 in cell migration and invasionPrincipal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE
Cell motility and the backward bulk flow of the plasma membrane componentsPrincipal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE
細胞運動における細胞極性決定の分子機序に関する研究Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Osaka Bioscience Institute
細胞接着シグナルを介したがん細胞の浸潤制御機構Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka Bioscience Institute
Role of paxillin-associatcd ARFGAPs in cell migration.Principal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE(OBI)
インテグリンを介する細胞接着シグナル制御と癌化細胞の生存性・侵潤能の解析Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
上皮間充織形質転換におけるインテグリン活性化と発がん機構の分子解析Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
上皮細胞における細胞接着を介した生存性シグナルの解析
- Principal Investigator
  
  橋本茂
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
インテグリンを介した単球/マクロファージの細胞運動性制御機構の解析Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
単球・マクロファージ細胞の接着及び貧食過程におけるパキシリンの機能解析Principal Investigator
- Principal Investigator
  
  左邊壽孝
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
細胞接着制御因子パキシリンの細胞周期M期特異的変化の分子機構の解析Principal Investigator
- Principal Investigator
  
  佐邊壽孝
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Osaka Bioscience Institute
Role of paxillin isoforms and their tyrosine phosphorylation in cell migration.Principal Investigator
- Principal Investigator
  
  SABE Hisataka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Cell biology
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE(OBI)
細胞運動性を制御する新規パキシリンアイソフォームの癌的細胞機構における役割Principal Investigator
- Principal Investigator
  
  佐邊嘉孝
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
インテグリンを介した炎症性マクロファージの血管内皮細胞への接着・侵入過程の分子機構、及び、血管内皮細胞の活性化機構の解明Principal Investigator
- Principal Investigator
  
  佐邉壽孝
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
細胞基質間接着制御機構の解明とその癌的増殖性への関与Principal Investigator
- Principal Investigator
  
  左邊壽孝
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
癌化における細胞基質間接着の低下と癌的増殖性との関連性の解析Principal Investigator
- Principal Investigator
  
  佐邉寿孝
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Redox Regulation and Cellular Signal Transduction
- Principal Investigator
  
  YODOI Junji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
Role of Integrin-mediated Signal Transduction in Cell Growth and Differentiation
- Principal Investigator
  
  SEKIGUCHI Kiyotoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Research Institute, Osaka Medical Center for Maternal and Child Health
免疫系における多様性発現機構の分子遺伝学的研究
- Principal Investigator
  
  本庶佑
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyoto University
宿主側から見た腫瘍増殖機序の分子免疫学的解析
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University

[Book] ArfGAPs: not only for the termination.2014
- Author(s)
  Shigeru Hashimoto, Ari Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Masanao Yoshino, Yutaro Otsuka, and Hisataka Sabe.
- Total Pages
  22
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26293057
[Book] ArfGAPs: not only for the termination.2014
- Author(s)
  Shigeru Hashimoto, Ari Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Masanao Yoshino, Yutaro Otsuka, and Hisataka Sabe.
- Total Pages
  22
- Publisher
  Springer
- Data Source
  KAKENHI-PLANNED-23112008
[Book] 「EMT-基礎的観点から」乳癌レビュー20122012
- Author(s)
  橋本あり、杉野弘和、橋本茂、佐邊壽孝
- Total Pages
  7
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PLANNED-23112008
[Book] 局所浸潤モデル－がんの浸潤転移に関わる分子　「疾患モデルの作製と利用－がん」2012
- Author(s)
  橋本あり、橋本茂、佐邊壽孝
- Total Pages
  11
- Publisher
  エル・アイ・シー（株）
- Data Source
  KAKENHI-PLANNED-23112008
[Book] 乳癌レビュー2012 EMT-基礎的観点から2011
- Author(s)
  橋本あり、杉野弘和、橋本茂、佐邊壽孝
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20247027
[Book] 蛋白質・核酸・酸素:細胞骨格と接着(第51巻第6号編集)2006
- Author(s)
  貝渕弘三、稲垣昌樹、佐邊壽孝
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17014083
[Book] 発生分化再生研究2005 実験医学増刊『上皮細胞における接着分子機能の動的制御』2005
- Author(s)
  三浦浩一, 佐邊壽孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16370090
[Book] 発生分化再生研究2005 実験医学増刊『上皮細胞における接着分子機能の動的制御』2005
- Author(s)
  三浦浩一, 佐邊壽孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17014083
[Book] 発生分化再生研究2005 実験医学増刊『上皮細胞における接着分子機能の動的制御』2005
- Author(s)
  三浦浩一, 佐邊壽孝
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults2023
- Author(s)
  Shirakawa Ryosuke、Nakajima Takayuki、Yoshimura Aya、Kawahara Yukako、Orito Chieko、Yamane Miwako、Handa Haruka、Takada Shingo、Furihata Takaaki、Fukushima Arata、Ishimori Naoki、Nakagawa Masao、Yokota Isao、Sabe Hisataka、Hashino Satoshi、Kinugawa Shintaro、Yokota Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5203-5203
- DOI
  10.1038/s41598-023-32549-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08046, KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-23K28026
[Journal Article] KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion2023
- Author(s)
  Sabe Hisataka
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 21 Issue: 1 Pages: 106-106
- DOI
  10.1186/s12964-023-01130-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02675
[Journal Article] Cross-disease communication between cancer and heart failure provides a rational approach to prevention and treatment of both diseases2022
- Author(s)
  Takada Shingo、Kinugawa Shintaro、Handa Haruka、Yokota Takashi、Sabe Hisataka
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 1-5
- DOI
  10.3389/fonc.2022.1006322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19754, KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-19K22791
[Journal Article] Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IX2022
- Author(s)
  Horikawa Mei、Sabe Hisataka、Onodera Yasuhito
- Journal Title
  
  Translational Oncology
  
  Volume: 15 Issue: 1 Pages: 101258-101258
- DOI
  10.1016/j.tranon.2021.101258
- NAID
  120007191779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21KK0140
[Journal Article] Treatments for skeletal muscle abnormalities in heart failure: sodium-glucose transporter 2 and ketone bodies2022
- Author(s)
  Takada Shingo、Sabe Hisataka、Kinugawa Shintaro
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 322 Issue: 2 Pages: H117-H128
- DOI
  10.1152/ajpheart.00100.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-19K22791
[Journal Article] Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure2022
- Author(s)
  Takada Shingo、Maekawa Satoshi、Furihata Takaaki、Kakutani Naoya、Setoyama Daiki、Ueda Koji、Nambu Hideo、Hagiwara Hikaru、Handa Haruka、Fumoto Yoshizuki、Hata Soichiro、Masunaga Tomoka、Fukushima Arata、Yokota Takashi、Kang Dongchon、Kinugawa Shintaro、Sabe Hisataka
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 41 Pages: 1-9
- DOI
  10.1073/pnas.2203628119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19754, KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-19K22791
[Journal Article] Strategies for all-at-once and stepwise selection of cells with multiple genetic manipulations2021
- Author(s)
  Horikawa Mei、Sabe Hisataka、Onodera Yasuhito
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 582 Pages: 93-99
- DOI
  10.1016/j.bbrc.2021.10.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21K19397
[Journal Article] Brain-derived neurotrophic factor improves impaired fatty acid oxidation via the activation of AMPKα-PGC1α signaling in skeletal muscle of mice with heart failure2021
- Author(s)
  Matsumoto J, Takada S, Furihata T, Nambu H, Kakutani N, Maekawa S, Mizushima W, Nakano I, Fukushima A, Yokota T, Tanaka S, Handa H, Sabe H, Kinugawa S
- Journal Title
  
  Circ Heart Fail
  
  Volume: 14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03360
[Journal Article] Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer2021
- Author(s)
  Hashimoto Ari、Handa Haruka、Hata Soichiro、Tsutaho Akio、Yoshida Takao、Hirano Satoshi、Hashimoto Shigeru、Sabe Hisataka
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 19 Issue: 1 Pages: 54-54
- DOI
  10.1186/s12964-021-00733-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08614, KAKENHI-PROJECT-21H02675
[Journal Article] Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer2021
- Author(s)
  橋本あり，半田　悠，畑宗一郎，蔦保暁生，吉田隆雄，平野　聡，橋本　茂，佐邊壽孝
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02608
[Journal Article] Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure2021
- Author(s)
  Furihata T, Takada S, Kakutani N, Maekawa S, Tsuda M, Matsumoto J, Mizushima W, Fukushima A, Yokota T, Enzan N, Matsushima S, Handa H, Fumoto Y, Nio-Kobayashi J, Iwanaga T, Tanaka S, Tsutsui H, Sabe H, Kinugawa S
- Journal Title
  
  Commun Biol
  
  Volume: 4 Pages: 138-138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03360
[Journal Article] Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance2021
- Author(s)
  Nambu H, Takada S, Maekawa S, Matsumoto J, Kakutani N, Furihata T, Shirakawa R, Katayama T, Nakajima T, Yamanashi K, Obata Y, Nakano I, Tsuda M, Saito A, Fukushima A, Yokota T, Nio-Kobayashi J, Yasui H, Higashikawa K, Kuge Y, Anzai T, Sabe H, Kinugawa S
- Journal Title
  
  Cardiovasc Res
  
  Volume: 117 Pages: 805-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03360
[Journal Article] Arid5a Promotes Immune Evasion by Augmenting Tryptophan Metabolism and Chemokine Expression2021
- Author(s)
  Parajuli Gyanu、Tekguc Murat、Wing James B.、Hashimoto Ari、Okuzaki Daisuke、Hirata Takeshi、Sasaki Atsushi、Itokazu Takahide、Handa Haruka、Sugino Hirokazu、Nishikawa Yoshihiro、Metwally Hozaifa、Kodama Yuzo、Tanaka Shinya、Sabe Hisataka、Yamashita Toshihide、Sakaguchi Shimon、Kishimoto Tadamitsu、Hashimoto Shigeru
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 9 Issue: 8 Pages: 862-876
- DOI
  10.1158/2326-6066.cir-21-0014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08614, KAKENHI-PROJECT-19H01171, KAKENHI-PROJECT-21H02675, KAKENHI-PROJECT-21K19878
[Journal Article] High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.2020
- Author(s)
  Tsutaho, A., Hashimoto, A., Hashimoto, S., Hata, S., Kachi, S., Hirano, S., and Sabe, H.
- Journal Title
  
  Cell Communication and Signaling
  
  Volume: 18(1) Issue: 1 Pages: 101-101
- DOI
  10.1186/s12964-020-00608-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08614, KAKENHI-PROJECT-18H02608
[Journal Article] ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics and immune evasion of pancreatic cancer2019
- Author(s)
  Hashimoto, S*., Furukawa, S*., Hashimoto, A*., Tsutaho, A., Fukao, A., Sakamura, Y., Parajuli, G., Onodera, Y., Otsuka, Y., Handa, H., Oikawa, T., Hata, S., Nishikawa Y., Mizukami, Y., Kodama, Y., Murakami M., Fujiwara, T., Hirano, S., and Sabe, H. (*Equally contributed)
- Journal Title
  
  Proceedings of the National Academy of the Sciences of the United States of America
  
  Volume: 116 Issue: 35 Pages: 17450-17459
- DOI
  10.1073/pnas.1901765116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08614, KAKENHI-PROJECT-18H02608, KAKENHI-PROJECT-17K07151, KAKENHI-PROJECT-17K09451, KAKENHI-PROJECT-17K09472
[Journal Article] Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection2019
- Author(s)
  Nishikawa Shigeto、Menju Toshi、Takahashi Koji、Miyata Ryo、Chen Yoshikawa Toyofumi Fengshi、Sonobe Makoto、Yoshizawa Akihiko、Sabe Hisataka、Sato Tosiya、Date Hiroshi
- Journal Title
  
  Cancer Management and Research
  
  Volume: Volume 11 Pages: 3419-3432
- DOI
  10.2147/cmar.s200819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02608, KAKENHI-PROJECT-17K10781, KAKENHI-PROJECT-18K19578
[Journal Article] Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells.2018
- Author(s)
  Handa, H*., Hashimoto, A*., Hashimoto S., Sugino, S., Oikawa, T., and Sabe, H.
- Journal Title
  
  Cell Commun. Signal.
  
  Volume: 16(1) Issue: 1 Pages: 94-94
- DOI
  10.1186/s12964-018-0302-6
- NAID
  120006585787
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07151, KAKENHI-PROJECT-17K08614, KAKENHI-PROJECT-18H02608
[Journal Article] p53-Dependent and -Independent Epithelial Integrity: Beyond miRNAs and Metabolic Fluctuations.2018
- Author(s)
  Oikawa T, Otsuka Y, Sabe H.
- Journal Title
  
  Cancers
  
  Volume: 10（6） Issue: 6 Pages: 162-162
- DOI
  10.3390/cancers10060162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02608, KAKENHI-PROJECT-16K08569
[Journal Article] ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis, and drug resistance.2016
- Author(s)
  Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, Oikawa T, Sabe H.
- Journal Title
  
  Oncogenesis.
  
  Volume: 5 Issue: 9 Pages: e259-e259
- DOI
  10.1038/oncsis.2016.60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057
[Journal Article] Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.2016
- Author(s)
  Hashimoto, S,. Mikami, S., Sugino, H., Yoshikawa, A., Hashimoto, A., Onodera, Y., Furukawa, S., Handa, H., Oikawa, T., Okada, Y., Oya, M. and Sabe, H.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 10656-10656
- DOI
  10.1038/ncomms10656
- NAID
  120005743066
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-15H04977, KAKENHI-PROJECT-25460422, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057
[Journal Article] High expression of the mesenchymal protein EPB41L5 correlates with poor prognosis of head and neck squamous cell carcinoma.2016
- Author(s)
  Otsuka Y, Sato H, Oikawa T, Onodera Y, Nam JM, Hashimoto A, Fukunaga K, Hatanaka KC, Hatanaka Y, Matsuno Y, Fukuda S, Sabe H.
- Journal Title
  
  Cell Comm. Signal.
  
  Volume: 14 Issue: 1 Pages: 28-28
- DOI
  10.1186/s12964-016-0151-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057
[Journal Article] P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.2016
- Author(s)
  Hashimoto, A., Oikawa, T., Hashimoto, S., Sugino, H., Yoshikawa, A., Otsuka, Y., Handa, H., Onodera, Y., Nam, J.M., Oneyama, C., Okada, M., Fukuda M. and Sabe, H.
- Journal Title
  
  J Cell Biol.
  
  Volume: 213 Issue: 1 Pages: 81-95
- DOI
  10.1083/jcb.201510002
- NAID
  120005763128
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PLANNED-26114006, KAKENHI-PROJECT-15H04367, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057
[Journal Article] Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells.2016
- Author(s)
  Handa H, Hashimoto A, Hashimoto S, Sabe, H.
- Journal Title
  
  Small GTPases
  
  Volume: － Issue: 5 Pages: 28-28
- DOI
  10.1080/21541248.2016.1249043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057
[Journal Article] Acquired platinum resistance involves epithelial-to-mesenchymal transition through ubiquitin ligase FBXO32 dysregulation2016
- Author(s)
  Tanaka N, Kosaka T, Miyazaki Y, Mikami S, Niwa N, Otsuka Y, Minamishima YA, Mizuno R, Kikuchi E, Miyajima A, Sabe H, Okada Y, Uhlen P, Suematsu M, Oya M
- Journal Title
  
  JCI insight
  
  Volume: 1 Issue: 18
- DOI
  10.1172/jci.insight.83654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04723, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-26462429, KAKENHI-PROJECT-15K15057, KAKENHI-PROJECT-26670163, KAKENHI-PROJECT-15K20110
[Journal Article] The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition2016
- Author(s)
  Komiya Y, Onodera Y, Kuroiwa M, Nomimura S, Kubo Y, Nam JM, Kajiwara K, Nada S, Oneyama C, Sabe H, Okada M.
- Journal Title
  
  Oncogenesis
  
  Volume: 5 Issue: 9 Pages: e258-e258
- DOI
  10.1038/oncsis.2016.59
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26114006, KAKENHI-PROJECT-15H04296, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-15K15057, KAKENHI-PROJECT-26830071
[Journal Article] AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.2014
- Author(s)
  Tien, D.N., Kishihata, M., Yoshikawa, A., Hashimoto, A., Sabe, H., Nishi, E., Kamei, K., Arai, H., Kita, T., Kimura, T., Yokode, M. and Ashida, N.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 5094-5094
- DOI
  10.1038/srep05094
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-25293182, KAKENHI-PROJECT-25461497, KAKENHI-PUBLICLY-26116715, KAKENHI-PROJECT-26293057, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26460121, KAKENHI-PROJECT-26670139
[Journal Article] High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients.2014
- Author(s)
  Sato H, Hatanaka KC, Hatanaka Y, Hatakeyama H, Hashimoto A, Matsuno Y, Fukuda S, Sabe H.
- Journal Title
  
  Cell Commun Signal.
  
  Volume: 12 Issue: 1 Pages: 17-17
- DOI
  10.1186/1478-811x-12-17
- NAID
  120005438264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-23590323, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-26462591
[Journal Article] β1-integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer.2013
- Author(s)
  Nam JM, Ahmed KM, Costes S, Zhang H, Onodera Y, Olshen AB, Hatanaka KC, Kinoshita R, Ishikawa M, Sabe H, Shirato H, Park CC.
- Journal Title
  
  Breast Cancer Res.
  
  Volume: 15 Issue: 4
- DOI
  10.1186/bcr3454
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008
[Journal Article] Intracellular trafficking of integrins in cancer cells.2013
- Author(s)
  Onodera Y, Nam JM, Sabe H.
- Journal Title
  
  Pharmacol Ther.
  
  Volume: 140 Issue: 1 Pages: 1-9
- DOI
  10.1016/j.pharmthera.2013.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-23791376, KAKENHI-PROJECT-25650060
[Journal Article] Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase2013
- Author(s)
  Miura, K.
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 45 Pages: 5292-5301
- DOI
  10.1038/onc.2012.571
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22114001, KAKENHI-PLANNED-22114002, KAKENHI-PROJECT-22240085, KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-24590406, KAKENHI-PROJECT-25250016, KAKENHI-PLANNED-22122003
[Journal Article] Co-overexpression of GEP100 and AMAP1 proteins correlates with rapid local recurrence after breast conservative therapy.2013
- Author(s)
  Kinoshita R, Nam JM, Ito YM, Hatanaka KC, Hashimoto A, Handa H, Otsuka Y, Hashimoto S, Onodera Y, Hosoda M, Onodera S, Shimizu S, Tanaka S, Shirato H, Tanino M, Sabe H.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 10 Pages: e76791-e76791
- DOI
  10.1371/journal.pone.0076791
- NAID
  120005348196
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-23590323, KAKENHI-PROJECT-24590406, KAKENHI-PROJECT-24790341, KAKENHI-PROJECT-25861050
[Journal Article] Grp1 plays a key role in linking insulin signaling to glut4 recycling2012
- Author(s)
  Li J., Malaby AW., Famulok M., Sabe H., Lambright DG., Hsu VW.
- Journal Title
  
  Dev Cell.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kg activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production2012
- Author(s)
  Mazaki Y., Nishimura Y. and Sabe H.
- Journal Title
  
  Mol. Cell Biol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Grp1 plays a key role in linking insulin signaling to glut4 recycling2012
- Author(s)
  Li J., Malaby AW., Famulok M., Sabe H., Lambright DG., Hsu VW.
- Journal Title
  
  Dev Cell
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008
[Journal Article] GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kg activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production.2012
- Author(s)
  Mazaki Y, Nishimura Y, Sabe H.
- Journal Title
  
  Mol Biol Cell.
  
  Volume: 23 Issue: 13 Pages: 2457-2467
- DOI
  10.1091/mbc.e12-01-0062
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008
[Journal Article] Rab5c mediates AMAP1-PRKD2 complexto enhance β1 integrin recycling inEGF-induced cancer invasion2012
- Author(s)
  Onodera Y., Nam JM., Hashimoto A., Norman JC., Shirato H., Hashimoto S. and Sabe H
- Journal Title
  
  J.Cell Biol
  
  Volume: 197 Issue: 7 Pages: 983-996
- DOI
  10.1083/jcb.201201065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370092, KAKENHI-PROJECT-23590323, KAKENHI-PROJECT-23791376, KAKENHI-PUBLICLY-23111501, KAKENHI-PLANNED-23112008
[Journal Article] Rab5c promotes AMAP1-PRKD2 complex formation to enhance ss1 integrin recycling in EGF-induced cancer invasion2012
- Author(s)
  Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H
- Journal Title
  
  J Cell Biol
  
  Volume: 197 Pages: 983-996
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Grp1 plays a key role in linking insulin signaling to glut4 recycling2012
- Author(s)
  Li J., Malaby AW., Famulok M., Sabe H., Lambright DG.and Hsu VW.
- Journal Title
  
  Dev Cell
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Rab5c mediates AMAP1-PRKD2 complex to enhance β1 integrin recycling in EGF-induced cancer invasion2012
- Author(s)
  Onodera Y., Nam JM., Hashimoto A., Norman JC., Shirato H., Hashimoto S. and Sabe H.
- Journal Title
  
  J.Cell Biol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Grp1 plays a key role in linking insulin signaling to glut4 recycling.2012
- Author(s)
  Li J, Malaby AW, Famulok M, Sabe H, Lambright DG, Hsu VW.
- Journal Title
  
  Dev Cell.
  
  Volume: 22 Issue: 6 Pages: 1286-1298
- DOI
  10.1016/j.devcel.2012.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112008
[Journal Article] Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.2012
- Author(s)
  Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 197 Pages: 983-996
- NAID
  120005946723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma2011
- Author(s)
  Menju T., Hashimoto S., Hashimoto A., Otsuka Y., Handa H., Ogawa E., Toda Y., Wada H., Date H. and Sabe H.
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 9 Pages: e25301-e25301
- DOI
  10.1371/journal.pone.0025301
- NAID
  120003464637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027, KAKENHI-PROJECT-21370092, KAKENHI-PROJECT-22657045, KAKENHI-PUBLICLY-23111501, KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-23590323
[Journal Article] EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating Ezrin through negative regulation of RhoA2011
- Author(s)
  Wakayama Y., Miura K., Sabe H. and Mochizuki N.
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 51 Pages: 44243-44253
- DOI
  10.1074/jbc.m111.267047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027, KAKENHI-PLANNED-23112008
[Journal Article] Cancer early dissemination : cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor β signalling2011
- Author(s)
  Sabe H.
- Journal Title
  
  J Biochem
  
  Volume: 149 Issue: 6 Pages: 633-639
- DOI
  10.1093/jb/mvr044
- NAID
  10030585535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027, KAKENHI-PLANNED-23112008
[Journal Article] GEP100-Arf6-AMAP1-cortactin pathway frequently used in cancer invasion is activated by VEGFR2 to promote angiogenesis2011
- Author(s)
  Hashimoto A., Hashimoto S., Ando R., Noda K., Ogawa E., Kotani H., Hirose M., Menju T., Morishige M., Manabe T., Toda Y., Ishida S. and Sabe H.
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 8 Pages: e23359-e23359
- DOI
  10.1371/journal.pone.0023359
- NAID
  120003295085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027, KAKENHI-PROJECT-21370092, KAKENHI-PROJECT-22657045, KAKENHI-PUBLICLY-23111501, KAKENHI-PLANNED-23112008, KAKENHI-PROJECT-23590323
[Journal Article] EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts2009
- Author(s)
  Miura K., Nam JM., Kojima C., Mochizuki N. and Sabe H.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 20 Issue: 7 Pages: 1949-1959
- DOI
  10.1091/mbc.e08-06-0549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis2009
- Author(s)
  Sabe H
- Journal Title
  
  Traffic 10
  
  Pages: 982-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Zyxin mediates actin fiber reorganization nepithelial-mesenchymal transition and contributes to endocardial morphogenesis.2009
- Author(s)
  Mori M., Nakagami H., Koibuchi N., Miura K., Takami Y., Koriyama H., Hayashi H., Sabe H., Mochizuki N., Morishita R., Kaneda Y.
- Journal Title
  
  Mol Biol Cell. 20
  
  Pages: 3115-3124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis2009
- Author(s)
  Mori M., Nakagami H., Koibuchi N., Miura K., Takami Y., Koriyama H., Hayashi H., Sabe H., Mochizuki N., Morishita R. and Kaneda Y.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 20 Issue: 13 Pages: 3115-3124
- DOI
  10.1091/mbc.e09-01-0046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts.2009
- Author(s)
  Miura K., Nam J.M., Kojima C., Mochizuki N., Sabe H.
- Journal Title
  
  Mol Biol Cell. 20
  
  Pages: 1949-1959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts2009
- Author(s)
  Miura K., Nam J.M., Kojima C., Mochizuki N., Sabe H.
- Journal Title
  
  Mol Biol Cell 20
  
  Pages: 1949-1959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.2009
- Author(s)
  Sabe H
- Journal Title
  
  Traffic 10
  
  Pages: 982-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis2009
- Author(s)
  Hisataka Sabe
- Journal Title
  
  Traffic 10
  
  Pages: 982-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.2009
- Author(s)
  Sabe H., Hashimoto S., Morishige M., Ogawa E., Hashimoto A., Nam J.M., Miura K., Yano H., Onodera Y.
- Journal Title
  
  Traffic 10
  
  Pages: 982-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis2009
- Author(s)
  Hisataka Sabe
- Journal Title
  
  Traffic 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis2009
- Author(s)
  Sabe H., Hashimoto S., Morishige M., Ogawa E., Hashimoto A., Nam JM., Miura K., Yano H.and Onodera Y.
- Journal Title
  
  Traffic
  
  Volume: 10 Issue: 8 Pages: 982-993
- DOI
  10.1111/j.1600-0854.2009.00917.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027, KAKENHI-PROJECT-21370092
[Journal Article] The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis2009
- Author(s)
  Sabe H., Hashimoto S., Morishige M., Ogawa E., Hashimoto A., Nam J.M., Miura K., Yano H., Onodera Y.
- Journal Title
  
  Traffic 10
  
  Pages: 982-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] GEP 100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion2008
- Author(s)
  M. Morlshige, S. Hashimoto, E. Ogawa, Y. Toda, H. Kotani, M. Hirose, S. Wei, A. Hashimoto, A. Yamada, H. Yano, Y. Mazaki, H. Kodama, Y. Nio, T. Manabe, H. Wada, H. Kobayashi, H. Sabe.
- Journal Title
  
  Nat. Cell Biol. 10
  
  Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] Fbox8 makes Arf6 refractory to function via ubiquitination.2008
- Author(s)
  H.Yano,I.Kobayashi,S.Hashimoto,F.Luton,M.Franco,K.Iwai,Z.Ronai & H.Sabe.
- Journal Title
  
  Mol. Biol. Cell 19
  
  Pages: 822-832
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] The EGFR-GEP100-Arf6 pathway in breast cancer : Full invasiveness is not from the inside2008
- Author(s)
  Hisataka Sabe
- Journal Title
  
  Cell adhesion & migration 2
  
  Pages: 71-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells.2008
- Author(s)
  Miyata M., Raven JF., Baltzis D., Koromilas AE., Sabe H.
- Journal Title
  
  Cell Cycle. 7
  
  Pages: 3273-3281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.2008
- Author(s)
  Morishige M., Hashimoto S., Ogawa E., Toda Y., Kotani H., Hirose M., Wei S., Hashimoto A., Yamada A., Yano H., Mazaki Y., Kodama H., Nio Y., Manabe T., Wada H., Kobayashi H., Sabe H.
- Journal Title
  
  Nat Cell Biol. 10
  
  Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] The EGFR-GEP100-Arf6 pathway in breast cancer: Full invasiveness is not from the inside.2008
- Author(s)
  Sabe H., Hashimoto S., Morishige M., Hashimoto A., Ogawa E.
- Journal Title
  
  Cell Adh Migr. 2
  
  Pages: 71-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Fbx8 makes Arf6 refractory to function via ubiquitination2008
- Author(s)
  Yano H., Kobayashi I., Onodera Y., Luton F., Franco M., Mazaki Y., Hashimoto S., Iwai K., Ronai Z. and Sabe H.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 19 Issue: 3 Pages: 822-832
- DOI
  10.1091/mbc.e07-08-0763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Dynamic rearrangement of surface proteins is essential for cytokinesis.2008
- Author(s)
  Bauer T., Motosugi N., Miura K., Sabe H., Hiiragi T.
- Journal Title
  
  Genesis 46
  
  Pages: 152-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion2008
- Author(s)
  Morishige M., Hashimoto S., Ogawa E., Toda Y., Kotani H., Hirose M., Wei S., Hashimoto A., Yamada A., Yano H., Mazaki Y., Kodama H., Nio Y., Manabe T., Wada H., Kobayashi H., Sabe H.
- Journal Title
  
  Nat Cell Biol. 10
  
  Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Fbox8 makes Arf6 refractory to function via ubiquitination.2008
- Author(s)
  H. Yano, I. Kobayashi, S. Hashimoto, F. Luton, M. Franco, K. Iwai, Z. Ronai & H. Sabe.
- Journal Title
  
  Mol. Biol. Cell 19
  
  Pages: 822-832
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during pithelial-mesenchymal transition2008
- Author(s)
  Hirano M., Hashimoto S., Yonemura S., Sabe H., Aizawa S.
- Journal Title
  
  J Cell Biol. 182
  
  Pages: 1217-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during pithelial-mesenchymal transition.2008
- Author(s)
  Hirano M., Hashimoto S., Yonemura S., Sabe H., Aizawa S.
- Journal Title
  
  J Cell Biol. 182
  
  Pages: 1217-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion2008
- Author(s)
  Morishige M., Hashimoto S., Ogawa E., Toda Y., Kotani H., Hirose M., Wei S., Hashimoto A., Yamada A., Yano H., Mazaki Y., Kodama H., Nio Y., Manabe T., Wada H., Kobayashi H. and Sabe H.
- Journal Title
  
  Nat Cell Biol
  
  Volume: 10 Issue: 1 Pages: 85-92
- DOI
  10.1038/ncb1672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Dynamic rearrangement of surface proteins is essential for cytokinesis.2008
- Author(s)
  T. Bauer, N. Motosugi, K. Miura, H. Sabe & T. Hiiragi.
- Journal Title
  
  Genesis 46
  
  Pages: 152-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] GEP 100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.2008
- Author(s)
  M. Morishige, S. Hashimoto, E. Ogawa, Y. Toda, H. Kotani, M. Hirose, S. Wei, A. Hashimoto, A. Yamada, H. Yano, Y. Mazaki, H. Kodama, Y. Nio, T. Manabe, H. Wada, H. Kobayashi & H. Sabe.
- Journal Title
  
  Nat. Cell Biol. 10
  
  Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Dynamic rearrangement of surface proteins is essential for cytokinesis.2008
- Author(s)
  T.Bauer,N.Motosugi,K.Miura,H.Sabe & T.Hiiragi.
- Journal Title
  
  Genesis 46
  
  Pages: 152-62
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] Fbox8 Makes Arf6 refractory to function via ubiquitination2008
- Author(s)
  H. Yano, I. Kobayashi, S. Hashimoto, F. Luton, M. Franco, K. Iwai, Z. Ronai, & H. Sabe.
- Journal Title
  
  Mol.Biol.Cell 19
  
  Pages: 822-832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] GEP100 links epidermal growth factor receptor signaling to invasiveness in breast tumors.2008
- Author(s)
  M. Morishige, S. Hashimoto, E. Ogawa, S. Wei, A. Hashimoto, A. Yamada, Y. Mazaki, Y. Toda, H. Wada, H. Kobayashi, H. Sabe.
- Journal Title
  
  Nat. Cell Biol 10
  
  Pages: 85-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition2008
- Author(s)
  Hirano M., Hashimoto S., Yonemura S., Sabe H.and Aizawa S.
- Journal Title
  
  J Cell Biol
  
  Volume: 182 Issue: 6 Pages: 1217-1230
- DOI
  10.1083/jcb.200712086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Dynaimc rearrangement of surface proteins is essential for cytokinesis2008
- Author(s)
  T. Bauer, N. Motosugi, K. Miura, H. Sabe,& T. Hiiragi.
- Journal Title
  
  Genesis 46
  
  Pages: 152-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] The EGFR-GEP100-Arf6 pathway in breast cancer : Full invasiveness is not from the inside2008
- Author(s)
  Sabe H., Hashimoto S., Morishige M., Hashimoto A. and Ogawa E.
- Journal Title
  
  Cell Adh Migr
  
  Volume: 2 Pages: 71-73
- URL
  http://www.landesbioscience.com/journals/celladhesion/SabeCAM2-2.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] IRES-mediated translational control of AMAP1 expression during differentiation of monocyte U937 cells2008
- Author(s)
  Miyata M., Raven JF., Baltzis D., Koromilas A.E. and Sabe H.
- Journal Title
  
  Cell Cycle
  
  Volume: 7 Pages: 3273-3281
- URL
  http://www.landesbioscience.com/journals/cc/MiyataCC7-20.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] Fbox8 makes Arf6 refractory tofunction via ubiquitination.2008
- Author(s)
  H. Yano, I. Kobayashi, S. Hashimoto, F. Luton, M. Franco, K. Iwai, Z. Ronai & H. Sabe.
- Journal Title
  
  Mol. Biol. Cell 19
  
  Pages: 822-832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] The EGFR-GEP100-Arf6 pathway in breast cancer:Full invasive ness is not from the inside2008
- Author(s)
  Hisataka Sabe
- Journal Title
  
  Cell adhesion & migration 2
  
  Pages: 71-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Fbx8 makes Arf6 refractory to function via ubiquitination.2008
- Author(s)
  Yano H., Kobayashi I., Onodera Y., Luton F., Franco M., Mazaki Y., Hashimoto S., Iwai K., Ronai Z., Sabe H.
- Journal Title
  
  Mol Biol Cell. 19
  
  Pages: 822-832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] The EGFR-GEP100-Arf6 pathway in breast cancer : full invasiveness is not from the inside.2008
- Author(s)
  H. Sabe, S. Hashimoto, A. Hashimoto, M. Morishige, E. Ogawa.
- Journal Title
  
  Cell Adhesion & Migration (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1.2008
- Author(s)
  Kon S., Tanabe K., Watanabe T., Sabe H., Satake M.
- Journal Title
  
  Exp Cell Res. 314
  
  Pages: 1415-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] GEP 100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.2008
- Author(s)
  M.Morishige,S.Hashimoto,E.Ogawa,Y.Toda,H.Kotani,M.Hirose,S.Wei,A.Hashimoto,A.Yamada,H.Yano,Y.Mazaki,H.Kodama,Y.Nio,T.Manabe,H.Wada,H.Kobayashi & H.Sabe.
- Journal Title
  
  Nat. Cell Biol. 10
  
  Pages: 85-92
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] Fbx8 makes Arf6 refractory to function via ubiquitination2008
- Author(s)
  Yano H., obayashi I., Onodera Y., Luton F., Franco M., Mazaki Y., Hashimoto S., Iwai K., Ronai Z., Sabe H.
- Journal Title
  
  Mol Biol Cell. 19
  
  Pages: 822-832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247027
[Journal Article] CIN85, a Cbl-interacting multiadaptor protein, is a component of AMAP1-mediated breast cancer invasion machinery.2007
- Author(s)
  J.Nam,Y.Onodera,Y.Mazaki,H.Miyoshi,S.Hashimoto & H.Sabe
- Journal Title
  
  EMBO J. 26
  
  Pages: 647-656
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] CIN85, a Cbl-interacting multiadaptor protein, is a component of AMAP1-mediated breast cancer invasion machinery.2007
- Author(s)
  J. Nam, Y. Onodera, Y. Mazaki, H. Miyoshi, S. Hashimoto, H. Sabe.
- Journal Title
  
  EMBO J. 26
  
  Pages: 647-656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] CIN85, a cb1-interacting multiadaptor protein,is a component of AMAP1-mediated breast cancer invasion machinery.2007
- Author(s)
  J.-M.Nam, Y.Onodera, Y.Mazaki, H.Miyoshi, S.Hashimoto, H.sabe
- Journal Title
  
  EMBO J. 26
  
  Pages: 647-656
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] CIN85, a Cbl-interacting multiabaptor protein, is a component of AMAP1-mediated breast cancer invasion machinery.2007
- Author(s)
  J. Nam, Y. Onodera, Y. Mazaki, H. Miyoshi, S.Hashimoto & H. Sabe
- Journal Title
  
  EMBO J. 26
  
  Pages: 647-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.2007
- Author(s)
  Nam JM., Onodera Y., Mazaki Y., Miyoshi H., Hashimoto S., Sabe H.
- Journal Title
  
  EMBO J. 26
  
  Pages: 647-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.2006
- Author(s)
  Y. Mazaki, S. Hashimoto, T. Tsujimura, M. Morishige, A. Hashimoto, K. Aritake, A. Yamada, J. Nam, H. Kiyonari, N. Kazuki, H. Sabe.
- Journal Title
  
  Nat. Immunol. 7
  
  Pages: 724-731
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] ArfGAP family proteins in cell adhesion, migration and tumor invasion.2006
- Author(s)
  H. Sabe, Y. Onodera, Y. Mazaki, S. Hashimoto.
- Journal Title
  
  Curr. Opin. Cell Biol. 18
  
  Pages: 558-564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] ArfGAP family proteins in cell adhesion, migration and tumor invasion2006
- Author(s)
  H.Sabe, Y.Onodera, Y.Mazaki, S.Hashimoto
- Journal Title
  
  Curr. Opin. Cell Biol. 18
  
  Pages: 558-564
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] ArfGAP family proteins in cell adhesion, migration and tumor invasion.2006
- Author(s)
  Sabe H., Onodera Y., Mazaki Y., Hashimoto S.
- Journal Title
  
  Curr Opin Cell Biol. 18
  
  Pages: 558-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.2006
- Author(s)
  Hashimoto S., Hirose M., Hashimoto A., Morishige M., Yamada A., Hosaka H., Akagi K., Ogawa E., Oneyama C., Agatsuma T., Okada M., Kobayashi H., Wada H., Nakano H., Ikegami T., Nakagawa A., Sabe H.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103
  
  Pages: 7036-7041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis2006
- Author(s)
  S.Hashimoto, M.Hirose, A.Hashimoto, M.Morishige, A.Yamada, H.Hosaka, K.Akagi, E.Ogawa, C.Oneyama, Agatsuma, T, M.Okada, H.Kobayashi, H.Wada, H.Nakano, T.Ikegami, A.Nakaeawa, H.Sabe
- Journal Title
  
  Proc Natl Acad Sci U S A. 103・17
  
  Pages: 7036-7041
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.2006
- Author(s)
  Mazaki Y., Hashimoto S., Tsujimura T., Morishige M., Hashimoto A., Aritake K., Yamada A., Nam JM., Kiyonari H., Nakao K., Sabe H.
- Journal Title
  
  Nat Immunol 7
  
  Pages: 724-731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2.2006
- Author(s)
  Y.Mazaki, S.Hashimoto, T.Tsujimura, M.Morishige, A.Hashimoto, K.Aritake, A.Yamada, J.-M.Nam, H.Kiyonari, N.Kazuki, H.Sabe
- Journal Title
  
  Nat. Immunol. 7
  
  Pages: 724-731
- Data Source
  KAKENHI-PROJECT-18370082
[Journal Article] ArfGAP family proteins in cell adhesion, migration and tumor invasion2006
- Author(s)
  H.Sabe, Y.Onodera, Y.Mazaki, S.Hashimoto
- Journal Title
  
  Curr. Opin. Cell Biol. 18
  
  Pages: 558-564
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Assays and properties of ArfGAPs, AMAP1 and AMAP2, in Arf6 function.2005
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Onodera, Y., Sabe, H.
- Journal Title
  
  Methods Enzymol. 404
  
  Pages: 213-231
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.2005
- Author(s)
  Onodera, Y., Hashimoto, S., Hashimoto, A., Morishige, M., Mazaki, Y., Yamada, A., Ogawa, E., Adachi, M., Sakurai, T., Manabe, T., Wada, H., Matsuura, N., Sabe, H.
- Journal Title
  
  EMBO J 24
  
  Pages: 963-973
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.2005
- Author(s)
  Y.Onodera, S.Hashimoto, A.Hashimoto, M.Morishige, Y.Mazaki, A.Yamada, E.Ogawa, M.Adachi, T.Sakurai, T.Manabe, H.Wada, N.Matsuura, H.Sabe
- Journal Title
  
  EMBO J. (in press)
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] Expression of AMAP1,an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.2005
- Author(s)
  Onodera, Y., Hashimoto, N., Hashimoto, A., Morishige, M., Mazaki, Y., Yamada, A., Ogawa, E., Adachi, M., Sakurai, T., Manabe, T., Wada, H., Matsuura, N., Sabe, H.
- Journal Title
  
  EMBO J. 24・5
  
  Pages: 963-973
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Assays and properties of the ArfGAPs, AMAP1 and AMAP2, in Arf6 function.2005
- Author(s)
  Hashimoto S., Hashimoto A., Yamada A., Onodera Y., Sabe H.
- Journal Title
  
  Methods Enzymol. 404
  
  Pages: 216-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Assays and properties of ArfGAPs, AMAP1 and AMAP2,in Arf6 function. Methods Enzymol.2005
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Onodera, Y., Sabe, H.
- Journal Title
  
  Methods Enzymol. 404
  
  Pages: 216-231
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration.2005
- Author(s)
  Woods, A.J., Kantidakis, T., Sabe, H., Critchley, D.R., Norman, J.C.
- Journal Title
  
  MOl. Cell Biol. 25・9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration.2005
- Author(s)
  Woods A.J., Kantidakis T., Sabe H., Critchley D.R., Norman JC.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 3763-3773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Expression of AMAP1, an ArfGAP, Provides novel targets to inhibit breast cancer invasive activities.2005
- Author(s)
  Y.Onodera, S.Hashimoto, A.Hashimoto, M.Morishige, Y.Mazaki, A.Yamada, E.Ogawa, M.Adachi, T.Sakurai, T.Manabe, H.Wada, N.Matsuura, H.Sabe
- Journal Title
  
  EMBO J. in press
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Assays and properties of ArfGAPs, AMAPI and AMAP2 in Arf6 function. Methods Enzymol.2005
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Onodera, Y., Sabe, H.
- Journal Title
  
  Methods Enzymol. 404
  
  Pages: 216-231
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration.2005
- Author(s)
  Woods, A.J., Kantidakis, T., Sabe, H., Critchley, D.R., Norman, J.C.
- Journal Title
  
  Mol.Cell Biol. 25・9
  
  Pages: 3763-3773
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Expression of AMAP1, an ArfGAP, provides novel targets to Inhibit breast cancer invasive activities.2005
- Author(s)
  Onodera, Y., Hashimoto, S., Hashimoto, A., Morishige, M., Mazaki, Y., Yamada, A., Ogawa, E., Adachi, M., Sakurai, T., Manabe, T., Wada, H., Matsuura, N., Sabe, H.
- Journal Title
  
  EMBO J. 24・5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration.2005
- Author(s)
  Woods, A.J., Kantidakis, T., Sabe, H., Critchley, D.R., Norman, J.C.
- Journal Title
  
  Mol. Cell Biol. 25・9
  
  Pages: 3763-3773
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.2005
- Author(s)
  Onodera Y., Hashimoto S., Hashimoto A., Morishige M., Mazaki Y., Yamada A., Ogawa E., Adachi M., Sakurai T., Manabe T., Wada H., Matsuura N., Sabe H.
- Journal Title
  
  EMBO J. 24
  
  Pages: 963-973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014083
[Journal Article] Interaction of paxillin with poly(A)-binding protein 1: a role in focal adhesion turnover and cell migration2005
- Author(s)
  Woods, A.J., Kandidakis, T., Sabe, H., Critchley, D.R., Norman, J.C.
- Journal Title
  
  Mol.Cell Biol. 25
  
  Pages: 3763-3773
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive.2004
- Author(s)
  Romanova, L.Y., Hashimoto, S., Chay, K.O., Blagosklonny, M.V., Sabe, H., Mushinski, J.F.
- Journal Title
  
  J. Cell Sci. 117・17
  
  Pages: 3759-3768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Requirement for Arf6 in breast cancer invasive activities.2004
- Author(s)
  S.Hashimoto, Y.Onodera, A.Hashimoto, M.Tanaka, M.Hamaguchi, A.Yamada, H.Sabe
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101・17
  
  Pages: 6647-6652
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive.2004
- Author(s)
  L.Y.Romanova, S.hashimoto, K.-O.Chay, M.V.Blagosklonny, H.Sabe, J.F.Mushinski.
- Journal Title
  
  J.Cell Sci. 117・17
  
  Pages: 3759-3768
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] A novel mode of action of an ArfGAP, PAG3/AMAP2/Papα, in Arf6 function.2004
- Author(s)
  S.Hashimoto, A.Hashimoto, A.Yamada, C.Kojima, H.Yamamoto, T.Tsutsumi, M.Higashi, A.Mizoguchi, R.Yagi, H.Sabe
- Journal Title
  
  J.Biol.Chem. 279・36
  
  Pages: 37677-37684
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] Regulation of Bin1 SH3 domain binding by phosphoinositides2004
- Author(s)
  Kojima, C., Hashimoto, A., Yabuta, I., Hirose, M., Hashimoto, S., Kanaho, Y., Sumimoto, H., Ikegami, T., Sabe, H.
- Journal Title
  
  EMBO J. 23
  
  Pages: 4413-4422
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] A novel mode of action of an ArfGAP, AMAP2/PAG3/PAPalpha in Arf6 function.2004
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Kojima, C., Yamamoto, H., Tsutsumi, T., Higashi, M., Mizoguchi, A., Yagi, R., Sabe, H.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 37677-37684
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Regulation of Bin1 SH3 domain binding by phosphoinositides.2004
- Author(s)
  C.Kojima, A.Hashimoto, I.Yabuta, M.Hirose, S.Hashimoto, Y.Kanaho, H.Sumimoto, T.Ikegami, H.Sabe
- Journal Title
  
  EMBO J. 23・22
  
  Pages: 4413-4422
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] A role played by a subset of integrin-signaling molecules in cadherin-based cell-cell adhesions.2004
- Author(s)
  H.Yano, Y.Mazaki, K.Kurokawa, S.K.Hanks, M.Matsuda, H.Sabe
- Journal Title
  
  J.Cell Biol. 166・2
  
  Pages: 283-295
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] Requirement for Arf6 in breast cancer invasive activities.2004
- Author(s)
  Hashimoto, S., Onodera, Y., Hashimoto, A., Tanaka, M., Hamaguchi, M., Yamad, A., Sabe, H.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 101・17
  
  Pages: 6647-6652
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive.2004
- Author(s)
  L.Y.Romanova, S.Hashimoto, K.-O.Chay, M.V.Blagosklonny, H.Sabe, J.F.Mushinski
- Journal Title
  
  J.Cell.Sci. 117・17
  
  Pages: 3759-3768
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Requirement for Arf6 in breast cancer invasive activities.2004
- Author(s)
  Hashimoto, S., Onodera, Y, Hashimoto, A., Tanaka, M., Hamaguchi, M., Yamada, A., Sabe, H.
- Journal Title
  
  Proc Natl Acad Sci USA 101
  
  Pages: 6647-6652
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Roles played by a subset of integrin-signaling molecules in cadherin-based cell-cell adhesion.2004
- Author(s)
  Yano, H., Mazaki, Y., Kurokawa, K., Hanks, K.S., Matsuda, M., Sabe, H
- Journal Title
  
  J.Cell Biol. 166
  
  Pages: 283-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Regulation of Bin1 SH3 domain binding by phosphoinositides.2004
- Author(s)
  C.Kojima, A.Hashimoto, I.Yabuta, M.Hirose, S.Hashimoto, Y.Kanaho, H.Sumimoto, T.Ikegami, H.Sabe
- Journal Title
  
  EMBO J. 23・22
  
  Pages: 4413-4422
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] A novel mode of action of an ArfGAP, PAG3/AMAP2/Papα, in Arf6 function.2004
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Kojima, C., Yamamoto, H., Tsutsumi, T., Higashi, M., Mizoguchi, A., Yagi, R., Sabe, H.
- Journal Title
  
  J. Biol. Chem. 279・36
  
  Pages: 37677-37684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Requirement for Arf6 in breast cancer invasive activities.2004
- Author(s)
  S.Hashimoto, Y.Onodera, A.Hashimoto, M.Tanaka, N.Hamaguchi, A.Yamada, H.Sabe
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101・17
  
  Pages: 6647-6652
- Data Source
  KAKENHI-PROJECT-12215157
[Journal Article] A novel mode of action of an ArfGAP,PAG3/AMAP2/Papα, in Arf6 function.2004
- Author(s)
  S.Hashimoto, A.Hashimoto, A.Yamada, C.Kojima, H.Yamamoto, T.Tsutsumi, M.Higashi, A.Mizoguchi, R.Yagi, H.Sabe
- Journal Title
  
  J.Biol.Chem. 279・36
  
  Pages: 37677-37684
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Ultraviolet A-induced production of matrix metalloproteinase-1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts.2004
- Author(s)
  Watanabe, H., Shimizu, T., Nishihira, J., Abe, R., Nakayama, T., Taniguchi, M., Sabe, H., Ishibashi, T., Shimizu H.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 1676-1683
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] A role played by a subset of integrin-signaling molecules in cadherin-based cell-cell adhesions.2004
- Author(s)
  Yano, H., Mazaki, Y., Kurokawa, K., Hanks.K.S., Matsuda, M., Sabe, H.
- Journal Title
  
  J. Cell Biol. 101・17
  
  Pages: 6647-6652
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] IL-3-induced phosphorylation of paxillin tyrosine residues 31 and 118 is required for polarization andmotility of pre-B lymphoid cells : TPA abolishes the effect of IL-3.2004
- Author(s)
  Romanova, L.Y., Hashimoto, S., Chay, K.O., Blagosklonny, M.V., Sabe, H., Mushinski, J.F.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 3759-3768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] A role played by a subset of integrin-signaling molecules in cadherin-based cell-cell adhesions.2004
- Author(s)
  H.Yano, Y.Mazaki, K.Kurokawa, S.K.Hanks, M.Matsuda, H.Sabe
- Journal Title
  
  J.Cell.Biol. 166・2
  
  Pages: 283-295
- Data Source
  KAKENHI-PROJECT-16370090
[Journal Article] Assays and properties of ArfGAPs, AMAP1 and AMAP2, in Arf6 function.
- Author(s)
  Hashimoto, S., Hashimoto, A., Yamada, A., Onodera Y., Sabe, H.
- Journal Title
  
  Methods Enzymol. 404
  
  Pages: 216-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] 心不全の病態の評価のための方法、バイオマーカー、候補化合物の評価方法、医薬品組成物及び心不全の治療剤2021
- Inventor(s)
  高田真吾、前川聡、横田卓、白川亮介、佐邊壽孝
- Industrial Property Rights Holder
  高田真吾、前川聡、横田卓、白川亮介、佐邊壽孝
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2024
- Data Source
  KAKENHI-PROJECT-21H02675
[Patent] 腎癌の再発リスクの予測に用いるための診断薬及びキット、並びに予測方法2015
- Inventor(s)
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Holder
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-17
- Data Source
  KAKENHI-PROJECT-26293057
[Patent] 膵癌の再発リスクの予測に用いるための診断薬及びキット、並びに予測方法2015
- Inventor(s)
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Holder
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-17
- Data Source
  KAKENHI-PROJECT-15K15057
[Patent] 腎癌の再発リスクの予測に用いるための診断薬及びキット、並びに予測方法2015
- Inventor(s)
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Holder
  佐邊壽孝、平野聡、古川聖太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-17
- Data Source
  KAKENHI-PLANNED-23112008
[Patent] 放射線治療増強薬及び放射線抵抗性癌の治療方法2013
- Inventor(s)
  佐邊壽孝、小野寺康仁、Nan Jin Min、橋本茂、橋本あり
- Industrial Property Rights Holder
  佐邊壽孝、小野寺康仁、Nan Jin Min、橋本茂、橋本あり
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-148970
- Filing Date
  2013-07-17
- Data Source
  KAKENHI-PLANNED-23112008
[Patent] 腎癌の再発リスクの予測に用いるための診断薬及びキット、並びに予測方法2013
- Inventor(s)
  佐邊壽孝、大家基嗣、三上修治
- Industrial Property Rights Holder
  佐邊壽孝、大家基嗣、三上修治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-148969
- Filing Date
  2013-07-17
- Data Source
  KAKENHI-PLANNED-23112008
[Patent] 乳癌乳房温存療法後の再発リスクの予測に用いるための診断薬並びに予測方法2013
- Inventor(s)
  佐邊壽孝、橋本茂、橋本あり、小野寺康仁、白土博樹、木下留美子
- Industrial Property Rights Holder
  佐邊壽孝、橋本茂、橋本あり、小野寺康仁、白土博樹、木下留美子
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-04
- Data Source
  KAKENHI-PLANNED-23112008
[Patent] 血管新生ならびに癌細胞のmesenchymal型およびamoeboid型浸潤を阻害するための薬剤2007
- Inventor(s)
  佐邊壽孝, 橋本茂, 橋本あり
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] 血管新生ならびに癌細胞のmesenchymal型およびamoeboid型浸潤を阻害するための薬剤2007
- Inventor(s)
  佐邊壽孝、橋本あり、橋本茂
- Industrial Property Rights Holder
  佐邊壽孝、橋本あり、橋本茂
- Acquisition Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] 非典型的なプロリンリッチ配列結合阻害剤2006
- Inventor(s)
  佐邊壽孝、橋本茂、中野洋文、我妻勉
- Industrial Property Rights Holder
  佐邊壽孝、橋本茂、中野洋文、我妻勉
- Acquisition Date
  2006-09-28
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] 非典型的なプロリンリッチ配列結合阻害剤2006
- Inventor(s)
  佐邊壽孝, 橋本茂, 中野洋文, 我妻勉
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所協和発酵工業(株)
- Filing Date
  2006-09-28
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] 血管新生ならびに癌細胞のmesenchymal型およびamoeboid型浸潤を阻害するための薬剤2006
- Inventor(s)
  佐邊壽孝、橋本あり、橋本茂
- Industrial Property Rights Holder
  佐邊壽孝、橋本あり、橋本茂
- Acquisition Date
  2006-09-28
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] ヒトがん細胞の浸潤活性を阻害するオリゴリボヌクレオチド2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 古林秀則, 森重真毅
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-30
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] 非典型的なプロリンリッチ配列結合阻害剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 中野洋文, 我妻勉
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] ヒト癌細胞の侵潤活性を阻害するオリゴリボヌクレオチド2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 古林秀則, 森重真毅
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] ヒトがん細胞の浸潤および転移を阻害するペプチド、それをコードするポリヌクレオチドおよびそれらを含有する薬剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-14
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] ヒトがん細胞の浸潤および転移を阻害するベプチド、それをコードするポリヌクレオチドおよびそれらを含有する薬剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] 非典型的なプロリンリッチ配列結合阻害剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 中野洋文, 我妻勉
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-29
- Data Source
  KAKENHI-PROJECT-17014083
[Patent] ヒトがん細胞の浸潤および転移を阻害するペプチド、それをコードするポリヌクレオチドおよびそれらを含有する薬剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-14
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] 非典型的なプロリンリッチ配列結合阻害剤2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 中野洋文, 我妻勉
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-29
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] ヒトがん細胞の浸潤活性を阻害するオリゴリボヌクレオチド2005
- Inventor(s)
  佐邊壽孝, 橋本茂, 古林秀則, 森重真毅
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2005-09-30
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] ヒト癌細胞の運動と浸潤を阻害する物質およびそのスクリーニング方法2004
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2004-09-06
- Data Source
  KAKENHI-PROJECT-12215157
[Patent] ヒト癌細胞の運動と浸潤を阻害する物質およびそのスクリーニング方法2004
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2004-09-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16370090
[Patent] ヒト癌細胞の運動と浸潤を阻害する物質およびそのスクリーニング方法2004
- Inventor(s)
  佐邊壽孝, 橋本茂
- Industrial Property Rights Holder
  (財)大阪バイオサイエンス研究所
- Filing Date
  2004-09-06
- Data Source
  KAKENHI-PROJECT-16370090
[Presentation] 上皮間葉転換におけるミトコンドリア機能制御機構2023
- Author(s)
  半田悠，小野寺康仁，高田真吾，横田卓，佐邊壽孝
- Organizer
  第22回ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] 上皮間葉転換における酸化的リン酸化の制御機構2023
- Author(s)
  半田悠，佐邊壽孝
- Organizer
  第13回シグナルネットワーク研究会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] 上皮間葉転換におけるmitoNEETの働き2023
- Author(s)
  半田悠，小野寺康仁，高田真吾，横田卓，佐邊壽孝
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] ARF6-AMAP1 pathway is linked to induction of immunosuppressive chemokine expression for favor immune evasion2023
- Author(s)
  Ari Hashimoto, Haruka Handa, Soichiro Hata, Daisuke Okuzaki, Yoshizuki Fumoto, Akio Tsutaho, Yoshihiro Nishikawa, Yuzo Kodama, Satoshi Hirano, Shigeru Hashimoto, and Hisataka Sabe
- Organizer
  第82回日本癌学会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] 上皮間葉転換(EMT)でミトコンドリア機能や動態はどう関わっているのか2022
- Author(s)
  半田悠、佐邊壽孝、高田真吾
- Organizer
  第95回生化学大会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] p53 modulates nuclear lipid composition and affects the nuclear entry of histone H3.12022
- Author(s)
  Tsukasa Oikawa, Junya Hasegawa, Naomi Ohnishi, Yasuhito Onodera, Ari Hashimoto, Junko Sasaki, Takehiko Sasaki, Koji Ueda and Hisataka Sabe
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Macroscopic order formation in myoblast populations driven by intracellular molecular dynamics2022
- Author(s)
  Yoshizuki Fumoto, Shingo Takada, Yasuhito Onodera, Kyogo Kawaguchi, Shigetsugu Hatakeyama, Hisataka Sabe, Tsukasa Oikawa
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] p53 は核脂質を調節しヒストンH3.1の核内侵入に影響を与える2022
- Author(s)
  Tsukasa Oikawa, Junya Hasegawa, Naomi Ohnishi, Yasuhito Onodera, Ari Hashimoto, Junko Sasaki, Takehiko Sasaki, Koji Ueda and Hisataka Sabe
- Organizer
  第74回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Arf6, the evolutionarily oldest G protein, is at the core of driving malignancy and immune evasion of pancreatic cancer cells2022
- Author(s)
  Soichiro Hata, Ari Hashimoto, Haruka Handa, Akio Tsutaho, Takao Yoshida, Yasuhito Onodera, Satoshi Hirano, Masahiro Sonoshita, Shigeru Hashimoto, and Hisataka Sabe
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Mitochondria after epithelial-mesenchymal transition (EMT) ~ their function and dynamics ~2021
- Author(s)
  Haruka Handa, Shingo Takada, Yasuhito Onodera, Yoshizuki Fumoto, Tsukasa Oikawa, Ari Hashimoto, Takashi Yokota, Soichiro Hata, and Hisataka Sabe
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Blocking the ARF6-AMAP1 pathway cooperatively improves anti-PD-1 immunotherapy for pancreatic cancer2021
- Author(s)
  Ari Hashimoto, Haruka Handa, Soichiro Hata, Akio Tsutaho, Takao Yoshida, Satoshi Hirano, Shigeru Hashimoto, and Hisataka Sabe
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Pancreatic KRAS/TP53 mutations promote ARF6-based immune evasion via activating mRNA translation and protein prenylation2021
- Author(s)
  Shigeru Hashimoto, Ari Hashimoto, Shotaro Furukawa, Akio Tsutaho, Yasuhito Onnodera, Yutaro Otsuka, Haruka Handa, Tsukasa Oikawa, Soichiro Hata, Akira Fukao, Yusuke Mizukami, Masaaki Murakami, Toshinobu Fujiwara, Satoshi Hirano, and Hisataka Sabe
- Organizer
  第7回北大部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] Mitochondrial metabolic reprograming in infarction-associated failing hearts2021
- Author(s)
  Shingo Takada, Shintaro Kinugawa, Hisataka Sabe
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21H02675
[Presentation] 不全心筋におけるミトコンドリア代謝リプログラミング2021
- Author(s)
  髙田真吾、絹川真太郎、佐邊壽孝
- Organizer
  日本生化学学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03360
[Presentation] マイオカインとミトコンドリア：加齢や疾患における摂道2021
- Author(s)
  絹川真太郎、髙田真吾、佐邊壽孝
- Organizer
  日本生化学学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03360
[Presentation] Upregulation of eIF4A/4E-dependent mRNA translation is the major target of KRAS signaling.2019
- Author(s)
  Hashimoto A, Hashimoto S, Furukawa S, Tsutaho A, Fukao A, Onodera Y, Handa H, Oikawa T, Hata S, Nishikawa Y, Mizukami Y, Kodama Y, Murakami M, Fujiwara T, Hirano S, and Sabe H.
- Organizer
  第19回蛋白質科学・第71回日本細胞生物合同年次大会
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] Pancreatic KRAS/TP53 oncogenes promote immune evasion via activating eIF4A/4E-dependent translation and protein prenylation2019
- Author(s)
  Hisataka Sabe
- Organizer
  The 38th Sapporo International Cancer Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] Pancreatic KRAS/TP53 mutations promote ARF6-based immune evasion via activating mRNA translation and protein prenylation.2019
- Author(s)
  Hashimoto A, Hashimoto S, Furukawa S, Tsutaho A, Fukao A, Onodera Y, Handa H, Oikawa T, Hata S, Nishikawa Y, Mizukami Y, Kodama Y, Murakami M, Fujiwara T, Hirano S, and Sabe H.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] Requirement for p53 in intra-nuclear dynamics of the K27-trimethylated histone H3 during DNA replication.2019
- Author(s)
  Tsukasa Oikawa, Naomi Ohnishi, Yasuhito Onodera, Ari Hashimoto, Koji Ueda and Hisataka Sabe
- Organizer
  第92回日本生化学会
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] p53 excludes EZH2 from H3.1 interactome during S phase to maintain histone code.2019
- Author(s)
  Oikawa T, Ohnishi N, Onodera Y, Hashimoto A, Ueda K, Sabe H
- Organizer
  The 38th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] Epithelial-mesenchymal transition accompanies mitochondrial fission and enhanced OXPHOS activity2018
- Author(s)
  Haruka Handa, Shingo Takada, Yutaro Otsuka, Yasuhito Onodera, Tsukasa Oikawa, Hisataka Sabe
- Organizer
  Nutrient Signaling 2018 Cold Spring Harbor Laboratory meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] Requirement for p53 in intra-nuclear dynamics of the K27-trimethylated histone H3 during DNA replication2018
- Author(s)
  Tsukasa Oikawa, Yuki Shino, Suguru Kurosawa, Yasuhito Onodera, Yutaro Otsuka, Ari Hashimoto, Hisataka Sabe
- Organizer
  第70回日本細胞生物学会（日本発生生物学会合同大会）
- Data Source
  KAKENHI-PROJECT-18H02608
[Presentation] 癌的代謝亢進によるミトコンドリア空間配置：転移性癌の治療抵抗性について2016
- Author(s)
  Hisataka Sabe
- Organizer
  第11回Basic Research Urology Seminar(BURS)
- Place of Presentation
  ANAクラウンプラザホテル千歳（千歳市）
- Year and Date
  2016-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Arf6-AMAP1 pathway drives mesenchymal metastasis and drug resistance of cancers under RTK and GPCR signaling2016
- Author(s)
  Hisataka Sabe
- Organizer
  OOTR第12回年次学会
- Place of Presentation
  ウエスティン都ホテル京都（京都府・京都市）
- Year and Date
  2016-03-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Arf6 is a core driver of mesenchymal invasion and metastasis, and therapeutic resistance of different types of cancers under RTK and GPCR signaling2016
- Author(s)
  Hisataka Sabe, Shigeru Hashimoto, Ari Hashimoto, Yutaro Otsuka, Haruka Handa, Tsukasa Oikawa, and Yasuhito Onodera
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2016-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] Malignant phenotype mediated by metabolism, transport and compartmentalization2016
- Author(s)
  Yasuhito Onodera, Mina Bissell, Hisataka Sabe
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] p53 antagonizes EZH2 function to maintain epithelial integrity2016
- Author(s)
  Tsukasa Oikawa, Yutaro Otsuka, Yasuhito Onodera, Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, Yutaka Suzuki, Hisataka Sabe
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] p53 antagonizes EZH2 function to maintain epithelial integrity2016
- Author(s)
  Tsukasa Oikawa, Yutaro Otsuka, Yasuhito Onodera, Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, Yutaka Suzuki, Hisataka Sabe
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Malignant phenotype mediated by metabolism, transport and compartmentalization2016
- Author(s)
  Yasuhito Onodera, Mina Bissell, Hisataka Sabe
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] Arf6-AMAP1 pathway drives mesenchymal metastasis and drug resistance of cancers under RTK and GPCR signaling2016
- Author(s)
  Hisataka Sabe
- Organizer
  OOTR第12回年次学会
- Place of Presentation
  ウエスティン都ホテル京都（京都府・京都市）
- Year and Date
  2016-03-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] がん細胞における小胞輸送経路を介したミトコンドリア分布制御と活性酸素および放射線への耐性2016
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Hiroki Shirato,　Hisataka Sabe
- Organizer
  日本放射線影響学会　第59回大会
- Place of Presentation
  ＪＭＳアステールプラザ（広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] Tumor responsiveness to mevalonate pathway inhibitors require overexpression of the Arf6 pathway2016
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Tsukasa Oikawa, Yutaro Otsuka, Haruka Handa, Yasuhito Onodera, Hisataka Sabe
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Arf6 is a core driver of mesenchymal invasion and metastasis, and therapeutic resistance of different types of cancers under RTK and GPCR signaling2016
- Author(s)
  Hisataka Sabe, Shigeru Hashimoto, Ari Hashimoto, Yutaro Otsuka, Haruka Handa, Tsukasa Oikawa, and Yasuhito Onodera
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2016-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Tumor responsiveness to mevalonate pathway inhibitors require overexpression of the Arf6 pathway2016
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Tsukasa Oikawa, Yutaro Otsuka, Haruka Handa, Yasuhito Onodera, Hisataka Sabe
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] 癌的代謝亢進によるミトコンドリア空間配置：転移性癌の治療抵抗性について2016
- Author(s)
  Hisataka Sabe
- Organizer
  第11回Basic Research Urology Seminar(BURS)
- Place of Presentation
  ANAクラウンプラザホテル千歳（千歳市）
- Year and Date
  2016-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] Arf6-AMAP1 pathway drives mesenchymal metastasis and drug resistance of cancers under RTK and GPCR signaling2016
- Author(s)
  Hisataka Sabe
- Organizer
  OOTR第12回年次学会
- Place of Presentation
  ウエスティン都ホテル京都（京都府・京都市）
- Year and Date
  2016-03-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] がん細胞における小胞輸送経路を介したミトコンドリア分布制御と活性酸素および放射線への耐性2016
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Hiroki Shirato,　Hisataka Sabe
- Organizer
  日本放射線影響学会　第59回大会
- Place of Presentation
  ＪＭＳアステールプラザ（広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] ZEB1-EPB4.1L5 axis drives mesenchymal-type invasion and metastasis of primary breast cancers2015
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Yutaro Otsuka, Jin-Min Nam, Yasuhito Onodera, Tsukasa Oikawa and Hisataka Sabe
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都・江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Arf6-AMAP1 pathway confers radioresistance via regulation of ROS in breast cancer2015
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Tsukasa Oikawa, Hiroki Shirato, Hisataka Sabe
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] ZEB1-EPB4.1L5 axis drives mesenchymal-type invasion and metastasis of primary breast cancers2015
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Yutaro Otsuka, Jin-Min Nam, Yasuhito Onodera, Tsukasa Oikawa and Hisataka Sabe
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都・江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] p53 warrants epithelial gene expressions through epigenetic regulation2015
- Author(s)
  Tsukasa Oikawa, Yasuhito Onodera, Yutaro Otsuka, Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, Yutaka Suzuki and Hisataka Sabe
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Grb2 promotes cancer invasive activities via EGF-induced GEP100-Arf6 pathway2015
- Author(s)
  Toshi Menju, Naoto Imamura, Shinya Neri, Hiroyuki Cho, Takao Nakanishi, Kei Shikuma, Terumasa Sowa, Makoto Sonobe, Hisataka Sabe, Stephan M Feller, Hiroshi Date
- Organizer
  第１８回欧州癌学会、第４０回欧州癌治療学会　共催
- Place of Presentation
  Messe Wien Exhibition & Congress Center（ウィーン・オーストリア）
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Arf6-AMAP1 pathway confers radioresistance via regulation of ROS in breast cancer2015
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Tsukasa Oikawa, Hiroki Shirato,　Hisataka Sabe
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Arf6-AMAP1 pathway confers radioresistance via regulation of ROS in breast cancer2015
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Tsukasa Oikawa, Hiroki Shirato,　Hisataka Sabe
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] p53 warrants epithelial gene expressions through epigenetic regulation2015
- Author(s)
  Tsukasa Oikawa, Yasuhito Onodera, Yutaro Otsuka, Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, Yutaka Suzuki and Hisataka Sabe
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 warrants epithelial gene expressions through epigenetic regulation2015
- Author(s)
  Tsukasa Oikawa, Yasuhito Onodera, Yutaro Otsuka, Haruka Handa, Ari Hashimoto, Shigeru Hashimoto, Yutaka Suzuki and Hisataka Sabe
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] Grb2 promotes cancer invasive activities via EGF-induced GEP100-Arf6 pathway2015
- Author(s)
  Toshi Menju, Naoto Imamura, Shinya Neri, Hiroyuki Cho, Takao Nakanishi, Kei Shikuma, Terumasa Sowa, Makoto Sonobe, Hisataka Sabe, Stephan M Feller, Hiroshi Date
- Organizer
  第１８回欧州癌学会、第４０回欧州癌治療学会　共催
- Place of Presentation
  Messe Wien Exhibition & Congress Center（ウィーン・オーストリア）
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] ZEB1-EPB4.1L5 axis drives mesenchymal-type invasion and metastasis of primary breast cancers2015
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Yutaro Otsuka, Jin-Min Nam, Yasuhito Onodera, Tsukasa Oikawa and Hisataka Sabe
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都・江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Grb2 promotes cancer invasive activities via EGF-induced GEP100-Arf6 pathway2015
- Author(s)
  Toshi Menju, Naoto Imamura, Shinya Neri, Hiroyuki Cho, Takao Nakanishi, Kei Shikuma, Terumasa Sowa, Makoto Sonobe, Hisataka Sabe, Stephan M Feller, Hiroshi Date
- Organizer
  第１８回欧州癌学会、第４０回欧州癌治療学会　共催
- Place of Presentation
  Messe Wien Exhibition & Congress Center（ウィーン・オーストリア）
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15057
[Presentation] RTKs-GEP100-Arf6-AMAP1 pathway mediates cancerous EMT in response to mutant p53 and TGFβ1 signaling2013
- Author(s)
  佐邊壽孝
- Organizer
  グローバルCOEシンポジウム
- Place of Presentation
  艮陵会館記念ホール（宮城県）
- Year and Date
  2013-02-01
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Targeting integrin suppresses invasive recurrence in a 3D model of radiation treated ductal carcinoma in situ2012
- Author(s)
  Jin-Min Nam, Kazi Mokim Ahmed, Sylvain Costes, Hui Zhang, Hisataka Sabe, Hiroki Shirato, Catherine C. Park
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] GAB1 links c-Met signaling with GEP100-Arf6-AMAP1 pathway to promote breast cancer invasiveness2012
- Author(s)
  Ayumu Yoshikawa, Shigeru Hashimoto, Ari Hashimoto, Hirokazu Sugino, Yutaro Otsuka, Shizuka Mito, Haruka Handa, Hisataka Sabe
- Organizer
  第31回札幌国際シンポジウム
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2-mediated downregulation of miR-203 promotes invasiveness of breast cancer cells2012
- Author(s)
  Hirokazu Sugino，Shigeru Hashimoto，Ari Hashimoto，Ayumu Yoshikawa，Haruka Handa，Hisataka Sabe
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Co-overexpression Of GEP100 With EGFR Correlates With Early Recurrence After Breast Conservation Therapy (BCT)2012
- Author(s)
  Kinoshita R, Nam JM, Hosoda M, Kubota KC, Tanino M, Hashimoto A, Ito YM, Tanaka S, Sabe H, Shirato H
- Organizer
  ASTRO 54th Annual meeting
- Place of Presentation
  Boston Convention and Exhibition Center(USA)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] INHIBITION OF INTEGRIN SUPPRESSES INVASIVE RECURRENCE IN A 3D MODEL OF RADIATION TREATED DCIS2012
- Author(s)
  Jin-Min Nam, Kazi Mokim Ahmed, Sylvain Costes, Hui Zhang, Hisataka Sabe, Hiroki Shirato, Catherine C. Park
- Organizer
  第10回未来創薬・医療イノベーション拠点形成国際シンポジウム
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Mutant-p53 generates GEP100-Arf6-AMAP1 pathway to promote breast cancer cell invasiveness in response to TGF β12012
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Ayumu Yoshikawa, Hirokazu Sugino, Haruka Handa, Sizuka Mito, Hiroki Sato, Yutaro Otsuka, Hinako Yoshino, Jin-Min Nam, Yasuhito Onodera, Hisataka Sabe
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2-MEDIATED DOWNREGULATION OF MIR-203 GENERATES THE ARF6-AMAP1 PATHWAY PIVOTAL FOR BREAST CANCER INVASIVENESS2012
- Author(s)
  Hirokazu Sugino，Shigeru Hashimoto，Ari Hashimoto，Ayumu Yoshikawa，Haruka Handa，Hisataka Sabe
- Organizer
  第31回札幌国際シンポジウム
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2 regulates breast cancer invasiveness through GEP100-Arf6-AMAP1 signaling pathway2012
- Author(s)
  Hirokazu Sugino，Shigeru Hashimoto，Ari Hashimoto，Ayumu Yoshikawa，Yutaro Otsuka，Haruka Handa，Hisataka Sabe
- Organizer
  第64回日本細胞生物学会／発生生物学会合同年会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Year and Date
  2012-05-30
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2012
- Author(s)
  佐邊壽孝
- Organizer
  Cell Migration in Biology and Medicine
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2012
- Author(s)
  佐邊壽孝
- Organizer
  平成23年度ライフサイエンスイノベージョン推進機構セミナー第371回学内セミナー
- Place of Presentation
  福井大学(福井県)(招待講演)
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] RTKs-GEP100-Arf6-AMAP1 pathway mediates cancerous EMT in response to mutant p53 and TGFβ signaling2012
- Author(s)
  Hisataka Sabe, Ari Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Yutaro Otsuka, Haruka Handa, Shizuka Mito, Hiroki Sato, Jin-Min Nam, Yasuhito Onodera, Shigeru Hashimoto
- Organizer
  第8回OOTR年次学会
- Place of Presentation
  ウェスティン都ホテル京都（京都府）
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] ガン研究における今後のバイオイメージングの課題2012
- Author(s)
  佐邊壽孝
- Organizer
  蛍光バイオイメージング・ミニシンポジウム
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2012-08-08
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2012
- Author(s)
  佐邊壽孝
- Organizer
  Cell Migration in Biology and Medicine
- Place of Presentation
  九州大学(福岡県)(招待講演)
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] EZH2-MEDIATED DOWNREGULATION OF MIR-203 GENERATES THE ARF6-AMAP1 PATHWAY PIVOTAL FOR BREAST CANCER INVASIVENESS2012
- Author(s)
  Hirokazu Sugino，Shigeru Hashimoto，Ari Hashimoto，Ayumu Yoshikawa，Haruka Handa，Hisataka Sabe
- Organizer
  BEATSON INTERNATIONAL ANCER CONFERENCE
- Place of Presentation
  University of Glasgow（イギリス）
- Year and Date
  2012-07-03
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Targeting beta1 integrin suppresses invasive recurrence in a three-dimensional model of radiation treated ductal carcinoma in situ2012
- Author(s)
  Nam JM, Ahmed KM, Costes S, Zhang H, Sabe H, Shirato H, Park CC
- Organizer
  ASTRO 54th Annual meeting
- Place of Presentation
  Boston Convention and Exhibition Center(USA)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] p53変異によるリガンド依存性癌浸潤転移シグナル経路の創出2012
- Author(s)
  佐邊壽孝
- Organizer
  第4回　Kansai Cardiovascular Metabolic Frontier
- Place of Presentation
  ヒルトン大阪（大阪府）
- Year and Date
  2012-10-06
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] GAB1 links c-Met signaling with GEP100-Arf6-AMAP1 pathway to promote breast cancer invasiveness2012
- Author(s)
  Ayumu Yoshikawa, Shigeru Hashimoto, Ari Hashimoto, Hirokazu Sugino, Yutaro Otsuka, Shizuka Mito, Haruka Handa, Hisataka Sabe
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2012
- Author(s)
  佐邊壽孝
- Organizer
  Cell Migration in Biology and Medicine
- Place of Presentation
  九州大学(福岡県)(招待講演)
- Year and Date
  2012-01-23
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] RTKs-GEP100-Arf6-AMAP1 pathway mediates cancerous EMT in response to mutant p53 and TGFβ1 signaling2012
- Author(s)
  佐邊壽孝
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-20
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2 suppresses miR-203 expression to promote cancer invasion2012
- Author(s)
  Shigeru Hashimoto, Hirokazu Sugino, Ari Hashimoto, Ayumu Yoshikawa, Yutaro Otsuka, Masanao Yoshino, Haruka Handa, Hisataka Sabe
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] 乳癌における発癌初期段階からの全身播種の分子機構とその予測バイオマーカー2012
- Author(s)
  佐邊壽孝
- Organizer
  平成24年JMTO臨床試験ワークショップ
- Place of Presentation
  第二豊田ビル（愛知県）
- Year and Date
  2012-06-23
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] mutant-p53 generates an Arf6 pathway to be activated by TGFβ1 and RTKs to promote ｉｎｖａｓｉｏｎ2012
- Author(s)
  佐邊壽孝
- Organizer
  第22回北九州がんセミナー
- Place of Presentation
  リーガロイヤルホテル小倉（福岡市）
- Year and Date
  2012-10-05
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] AMAP1 promotes β1 integrin recycling via PRKD2 and Rab5c in EGF-induced invasion of breast cancer cells (104/120)2012
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Shigeru Hashimoto, Ari Hashimoto, Hiroki Shirato, Hisataka Sabe
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] MUTANT-p53 GENERATES GEP100-Arf6-AMAP1 PATHWAY TO PROMOTE BREAST CANCER CELL INVASIVENESS IN RESPONSE TO TGFβ12012
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Ayumu Yoshikawa, Hirokazu Sugino, Haruka Handa, Sizuka Mito, Hiroki Sato, Yutaro Otsuka, Hinako Yoshino, Jin-Min Nam, Yasuhito Onodera, Hisataka Sabe
- Organizer
  第31回札幌国際シンポジウム
- Place of Presentation
  北海道大学（北海道）
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2012
- Author(s)
  佐邊壽孝
- Organizer
  平成23年度ライフサイエンスイノベージョン推進機構セミナー第371回学内セミナー
- Place of Presentation
  福井大学(福井県)(招待講演)
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Roles of Arf6-AMAP1-PKD2 pathway in disorganization of epithelial architecture2012
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Ari Hashimoto, Mina Bissell, Shigeru Hashimoto, Hisataka Sabe
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2011
- Author(s)
  佐邊壽孝
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2011
- Author(s)
  佐邊壽孝
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] p53 mutation and TGFβ signaling culminate in cancer invasiveness via GEP100-Arf6-AMAP1 pathway2011
- Author(s)
  佐邊壽孝
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] The Arf6-AMAP1 Pathway Contributes to Cancerous EMT2010
- Author(s)
  Sabe H
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] The Arf6-AMAP1 Pathway Contributes to Cancerous EMT2010
- Author(s)
  佐邊壽孝
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] The Arf6-AMAP1 Pathway Contributes to Cancerous EMT2010
- Author(s)
  佐邊壽孝
- Organizer
  第30回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学(札幌市) 招待講演
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis2010
- Author(s)
  佐邊壽孝
- Organizer
  第6回OOTR年次学会
- Place of Presentation
  ウェスティン都ホテル京都(京都府)
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis2010
- Author(s)
  Sabe H
- Organizer
  第6回OOTR年次学会
- Place of Presentation
  京都
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] 転移部における癌の休眠と再発:癌的EMTから考える2010
- Author(s)
  佐邊壽孝
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] 癌の初期播種と転移部における癌の休眠と再発:癌的EMTから考える2010
- Author(s)
  佐邊壽孝
- Organizer
  JSTさきがけ研究同窓会発表会
- Place of Presentation
  長崎大学(長崎市) 招待講演
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis.2010
- Author(s)
  Sabe H
- Organizer
  第6回OOTR年次学会
- Place of Presentation
  京都
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] 転移部における癌の休眠と再発:癌的EMTから考える2010
- Author(s)
  佐邊壽孝
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場(大阪市) 招待講演
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis2010
- Author(s)
  Sabe H
- Organizer
  第6回OOTR年次学会
- Place of Presentation
  ウェスティン都ホテル京都(京都市)
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis.2010
- Author(s)
  Sabe H
- Organizer
  第6回OOTR年次学会
- Place of Presentation
  ウェスティン都ホテル京都(京都市)
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] The Arf6-AMAP1 Pathway Contributes to Cancerous EMT2010
- Author(s)
  佐邊壽孝
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪市) 招待講演
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] The Arf6-AMAP1 Pathway Contributes to Cancerous EMT2010
- Author(s)
  佐邊壽孝
- Organizer
  第30回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis.2009
- Author(s)
  Sabe H
- Organizer
  2009 FEBS workshop
- Place of Presentation
  Seefeld
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis2009
- Author(s)
  Sabe H
- Organizer
  2009 FEBS workshop
- Place of Presentation
  Hotel Veronika(ミュンヘン)
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis2009
- Author(s)
  佐邊壽孝
- Organizer
  2009 FEBS workshop
- Place of Presentation
  Hotel Veronika(Seefeld)
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis.2009
- Author(s)
  Sabe H
- Organizer
  2009 FEBS workshop
- Place of Presentation
  Seefeld
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] メンブレントラフィックと癌浸潤形質獲得機序2009
- Author(s)
  Sabe H
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] 癌の浸潤形質獲得機序:その組織特異性についての考察2009
- Author(s)
  Sabe H
- Organizer
  生化学会支部例会
- Place of Presentation
  旭川医科大学(旭川市)
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] 乳がんの浸潤性獲得機序:微小環境を考える2009
- Author(s)
  Hisataka Sabe
- Organizer
  がん特定領域5領域合同シンポジウム
- Place of Presentation
  学術総合センター一橋記念講堂
- Year and Date
  2009-02-02
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] メンブレントラフィックと癌浸潤形質獲得機序2009
- Author(s)
  佐邊壽孝
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] 癌の浸潤形質獲得機序:その組織特異性についての考察2009
- Author(s)
  Sabe H
- Organizer
  生化学会支部例会
- Place of Presentation
  旭川医科大学(旭川市)
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] メンブレントラフィックと癌浸潤形質獲得機序2009
- Author(s)
  Sabe H
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] メンブレントラフィックと癌浸潤形質獲得機序2009
- Author(s)
  Sabe H
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Integrin activation and E-cadherin inactivation by the Arf6 pathway specific to breast cancer invasion and metastasis.2009
- Author(s)
  Sabe H
- Organizer
  2009 FEBS workshop
- Place of Presentation
  Hotel Veronika(ミュンヘン)
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] メンブレントラフィックと癌浸潤形質獲得機序2009
- Author(s)
  Sabe H
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20247027
[Presentation] The ECFR-GEP100-Arf6 pathway in breast cancer:full invasiveness is not from the inside2008
- Author(s)
  Hisataka Sabe
- Organizer
  第2回日本癌学会・アメリカ癌学会合同カンファレンス
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場
- Year and Date
  2008-07-15
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] 乳癌の浸潤転移に特異的EGFR-GEP100-Arf6-AMAP1経路2008
- Author(s)
  Hisataka Sabe
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Arf6 constitutes a central pathway involved in breast cancer cell invasion and metastasis2007
- Author(s)
  H. Sabe
- Organizer
  The 4th annual conference of the Organisation for Oncology and Translational Research
- Place of Presentation
  イタリア
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Arf6 constitutes a central pathway involved in breast cancer cell invasion and metastasis2007
- Author(s)
  H. Sabe
- Organizer
  The 4th annual conference of the Organisation for Oncology and Translational Research
- Place of Presentation
  イタリア
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-18370082
[Presentation] Arf6 constitutes a central pathway involved in breast cancer cell invasion and metastasis.2007
- Author(s)
  H. Sabe.
- Organizer
  2007 FASEB Summer Research Conferences and Jacob Monod Conferences Arf family GTPases
- Place of Presentation
  II Ciocco, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Presentation] Arf6 constitutes a central pathway involved in breast cancer cell invasion and metastasis2007
- Author(s)
  H.Sabe
- Organizer
  2007 FASEB Summer Research Conferences and Jacob Monod Conferences "Arf family GTPases"
- Place of Presentation
  II Ciocco,Italy
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370082
[Presentation] Arf6 constitutes a signaling pathway involved in the invasive phenotypes of primary tumors of the human breast.2007
- Author(s)
  Sabe H
- Organizer
  FASEB Summer Research Conferences, II Ciocco
- Place of Presentation
  Tuscany, Italy
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] How invasive Phenotypes Arise in Primary Tumors of Human Breast2006
- Author(s)
  Sabe H
- Organizer
  Burnham institute for Medical Research
- Place of Presentation
  CA, USA
- Year and Date
  2006-12-11
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Cancer Cell Invation:How the invative phenotypes arises in Breast Tumors2006
- Author(s)
  Sabe H
- Organizer
  Beatson Institute Worksho
- Place of Presentation
  Glasgow, UK
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Reglation of cancer cell mobility2005
- Author(s)
  Sabe H
- Organizer
  Montebello Conference 2005
- Place of Presentation
  Olso, Norway
- Data Source
  KAKENHI-PROJECT-17014083
[Presentation] Robust redox homeostasis mediated by Arf6-AMAP1 pathway confers resistance to ionizing radiation in breast cancer
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Tsukasa Oikawa, Hiroki Shirato and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Analysis of molecular mechanism involved in invasiveness of
- Author(s)
  Jin-Min Nam, Yasuhito Onodera, Hisataka Sabe, Hiroki Shirato
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Different genome statuses in breast cancer and renal cancer generate the Arf6-based mesenchymal machinery critical for metastasis and poor survival
- Author(s)
  Hisataka Sabe, Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Yutaro Otsuka, Tsukasa Oikawa, Shuji Mikami, Mototsugu Oya
- Organizer
  The 4th Global Cancer Genomics Consortium Symposium
- Place of Presentation
  芝蘭会館（京都市）
- Year and Date
  2014-11-14 – 2014-11-15
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Mutant-p53 generates the GEP100-Arf6-AMAP1 pathway to promote breast cancer invasiveness
- Author(s)
  Shigeru Hashimoto, Ari Hashimoto, Chitose Oneyama, Ayumu Yoshikawa, Hirokazu Sugino, Haruka Handa, Masanao Yoshino, Yutaro Otsuka, Yasuhito Onodera, Masato Okada, Hisataka Sabe
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2 overexpression generates Arf6-based mesenchymal invasion machinery that is activated by LPA and central to poor prognosis of renal cancer
- Author(s)
  Shigeru Hashimoto, Hirokazu Sugino, Ari Hashimoto, Ayumu Yoshikawa, Tsukasa Oikawa, Haruka Handa, Mototsugu Oya, Shuji Mikami, and Hisataka Sabe
- Organizer
  Mechanisms & Models of Cancer
- Place of Presentation
  Cold Spring Harbor Laboratory(USA)
- Year and Date
  2014-08-12 – 2014-08-16
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] 癌の再発予測と再発部治療
- Author(s)
  佐邊壽孝
- Organizer
  第8回神戸がん研究会
- Place of Presentation
  神緑会館（神戸市）
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Mechanisms by which oncogenic mutant-p53 generates mesenchymal invasive pathway pivotal to a radiation resistance
- Author(s)
  Hisataka Sabe, Ari Hashimoto, Shigeru Hashimoto, Yasuhito Onodera, Tsukasa Oikawa, Jin-Min Nam, Chitose Oneyama, Hirokazu Sugino, Ayumu Yoshikawa, Yutaro Otsuka, Haruka Handa, Masanao Yoshino, Masato Okada
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Invited
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Robust redox homeostasis mediated by Arf6-AMAP1 pathway confers resistance to ionizing radiation in breast cancer
- Author(s)
  Yasuhito Onodera, Jin-Min Nam, Tsukasa Oikawa, Hiroki Shirato and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] p53 recalls epithelial memory in mammary cancer cells with mesenchymal phenotypes
- Author(s)
  Tsukasa Oikawa, Yasuhito Onodera, Ari Hashimoto, Shigeru Hashimoto, and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] TP53 alterations generate Arf6-based mesenchymal invasion pathway that is activated by RTKs and TGFβ1 in breast cancer
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Tsukasa Oikawa, Yasuhito Onodera, Haruka Handa, Yutaro Otsuka, Kosuke Iwami, Hiroki Sato, Chitose Oneyama, Masato Okada, Satoshi Fukuda, Mitsunori Fukuda, and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Possible mechanisms of non-invasive to invasive phenotypic conversion of breast cancer cells upon radiation
- Author(s)
  Jin-Min Nam, Yasuhito Onodera, Masayori Ishikawa, Hisataka Sabe, Hiroki Shirato
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] p53 recalls epithelial memory in mammary cancer cells with mesenchymal phenotypes
- Author(s)
  Tsukasa Oikawa, Yasuhito Onodera, Ari Hashimoto, Shigeru Hashimoto, and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] EZH2 overexpression generates Arf6-based mesenchymal invasion machinery that is activated by LPA and central to poor prognosis of renal cancer
- Author(s)
  Shigeru Hashimoto, Hirokazu Sugino, Ari Hashimoto, Ayumu Yoshikawa, Tsukasa Oikawa, Haruka Handa, Mototsugu Oya, Shuji Mikami, and Hisataka Sabe
- Organizer
  Mechanisms & Models of Cancer
- Place of Presentation
  Cold Spring Harbor Laboratory(USA)
- Year and Date
  2014-08-12 – 2014-08-16
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Analysis of molecular mechanism involved in invasiveness of
- Author(s)
  Jin-Min Nam, Yasuhito Onodera, Hisataka Sabe, Hiroki Shirato
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] Mechanisms by which p53 alterations generate GEP100-Arf6-AMAP1 pathway as a mesenchymal invasion machinery to be activated by RTK-ligands and TGBβ1
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Yasuhito Onodera, Tsukasa Oikawa, Chitose Oneyama, Rumiko Kinoshita, Jin-Min Nam, Mishie Tanino, Hirokazu Sugino, Ayumu Yoshikawa, Yutaro Otsuka, Haruka Handa, Masanao Yoshino, Hiroki Sato, Satoshi Fukuda, Shinya Tanaka, Hiroki Shirato, Yoichi Ito, Masato Okada, and Hisataka Sabe
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PLANNED-23112008
[Presentation] Different genome statuses in breast cancer and renal cancer generate the Arf6-based mesenchymal machinery critical for metastasis and poor survival
- Author(s)
  Hisataka Sabe, Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Haruka Handa, Yutaro Otsuka, Tsukasa Oikawa, Shuji Mikami, Mototsugu Oya
- Organizer
  The 4th Global Cancer Genomics Consortium Symposium
- Place of Presentation
  芝蘭会館（京都市）
- Year and Date
  2014-11-14 – 2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293057
[Presentation] TP53 alterations generate Arf6-based mesenchymal invasion pathway that is activated by RTKs and TGFβ1 in breast cancer
- Author(s)
  Ari Hashimoto, Shigeru Hashimoto, Hirokazu Sugino, Ayumu Yoshikawa, Tsukasa Oikawa, Yasuhito Onodera, Haruka Handa, Yutaro Otsuka, Kosuke Iwami, Hiroki Sato, Chitose Oneyama, Masato Okada, Satoshi Fukuda, Mitsunori Fukuda, and Hisataka Sabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293057

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# of Collaborated Projects: 8 results

# of Collaborated Products: 19 results
2. MAZAKI Yuichi (60311304)

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# of Collaborated Projects: 1 results

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108. PARK Sang Chul

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109. STORZ Gisela

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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112. チュルソトーマス

# of Collaborated Projects: 1 results

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113. コルスマイヤースタンレ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
114. チュルツトマス

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
115. キンユン

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
116. キャンビアジョン

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
117. 花房秀三郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
118. 近藤明子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
119. Kajiwara Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
120. 石森直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
121. 南嶋洋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
122. 岡田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sabe Hisataka 佐邊 壽孝

SABE Hisataka 佐邊 壽孝

左邊 壽孝 サベ ヒサタカ

佐邉 壽孝 サベ ヒサタカ

佐邊 嘉孝 サベ ヒサタカ

佐邉 寿孝 サベ ヒサタカ

佐辺 寿孝 サベ ヒサタカ

佐邊 寿孝

佐邊 壽孝

Research Projects

Research Products

Co-Researchers

スクシニルCoAによる心筋代謝機構の解明

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Elucidation of the molecular basis of ARF6-AMAP1 pathway-dependent chemokine expression switch in response to the same stimulusPrincipal Investigator

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Elucidation of the mechanism by which myokines regulate aging progress

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The biological significance of the diversity of the epithelial cell integrityPrincipal Investigator

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Mechansim by which Arf6 protein becomes overexpressed in cancer to promote malignancyPrincipal Investigator

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TP53 mutation drives cancer IR-resistance via the Arf6-based pathwayPrincipal Investigator

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An evaluation for identification of signaling pathway to make progress EMT of thoracic malignant tumor and evaluation of clinical specimens.

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Roles of ARFs in superoxide production and chemotaxis of neutrophil

Principal Investigator

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Luminal epithelium integrity and the EMTPrincipal Investigator

Principal Investigator

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Research Institution

Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for Real-time Tracking Medical Science

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Invasiveness acquired during EMTPrincipal Investigator

Principal Investigator

Sabe Hisataka 佐邊壽孝

SABE Hisataka 佐邊壽孝

左邊壽孝サベヒサタカ

佐邉壽孝サベヒサタカ

佐邊嘉孝サベヒサタカ

佐邉寿孝サベヒサタカ

佐辺寿孝サベヒサタカ

佐邊寿孝

佐邊壽孝