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KAWAGUCHI Hiroshi  川口 浩

ORCIDConnect your ORCID iD *help
Researcher Number 40282660
External Links
Affiliation (based on the past Project Information) *help 2013 – 2016: 東京大学, 医学部附属病院, 届出診療医
2015: 東京大学, 医学部附属病院, 届出診療員
2014: 東京大学, 医学部附属病院, 届出医診療医
2013 – 2014: 東京大学, 医学部附属病院, その他
2006 – 2012: 東京大学, 医学部附属病院, 准教授 … More
2011: 東京大学, 医学部・附属病院, 准教授
2007 – 2008: The University of Tokyo, Hospital, Associate Professor
2007: 東京大学, 医学部付属病院, 准教授
2006: Tokyo Univ of Tokyo, Faculty of Medicine, Associate Professor
2004 – 2006: The University of Tokyo, Department of Orthopedics, Assistant professor, 医学部附属病院, 助教授
2002 – 2003: Faculty of Medicine, Lecturer, 医学部附属病院, 講師
1998 – 2001: 東京大学, 医学部・附属病院, 講師
1999: 東京大学, 医学部・付属病院, 講師
1998: 東京大学, 医学部附属病院, 講師
1997: 東京大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery / Biological Sciences
Except Principal Investigator
Orthopaedic surgery / Orthopaedic surgery / Surgical dentistry / Biomedical engineering/Biological material science / Respiratory organ internal medicine / Morphological basic dentistry / 矯正・小児・社会系歯学
Keywords
Principal Investigator
骨 / 変形性関節症 / 軟骨 / 軟骨細胞 / bone / fracture / 成長因子 / fibroblast growth factor / 骨折 / chondrocyte … More / 整形外科学 / 脊椎脊髄病学 / 軟骨代謝 / 骨芽細胞 / サイクリン / 細胞周期 / 変形性脊椎症 / 骨粗鬆症 / klotho / 老化 / knockout mouse / osteoarthritis / osteoporosis / mechanical stress / ノックアウトマウス / メカニカルストレス / growth factor / osteoclast / osteoblasts / cartilage / fibroblast growth factor (FGF) / 下皮骨細胞 / 破骨細胞 / Fibroblast growth factor / bone resorption / bone formation / rheumatoid arthritis / primates / サイトカイン / 骨代謝 / 類人猿(サル) / 骨形成 / 骨吸収 / 慢性関節リウマチ / 類人猿 / 塩基性線維芽細胞増殖因子 / hypoxia / autophagy / オートファジー / 低酸素 / 関節軟骨 / 骨軟骨代謝学 / 外科学 / 関節病学 / 椎間板変性 / 椎間板 / ゲノムワイド関連解析 / 変形性腰椎症 / Pax8 / 甲状腺ホルモン / プロモータ / 転写制御 / 軟骨内骨化 / p63 / 転写因子 / 軟骨代謝学 / トランスジェニックマウス / Cyclin dependent kinase / 分化 / BMP / CDK / ウイルス / 安定性 / DNA / 遺伝子治療 / ミセル / 高分子 / 遺伝子ベクター / 遺伝子導入 / SNP / 遺伝子多型 / 遺伝子解析 / PPAR-γ / IRS / PPARγ / PPAR-gamma / インスリン受容体基質(IRS) / 副甲状腺ホルモン(PTH) … More
Except Principal Investigator
骨 / 変形性関節症 / 軟骨 / 骨粗鬆症 / bone / 破骨細胞 / ノックアウトマウス / 軟骨細胞 / 骨芽細胞 / 軟骨分化 / 骨代謝 / cystatin 10 / 老化 / ゲノム / 骨形成 / 再生医療 / nanotechnology / ナノテクノロジー / osteoarthritis / knockout mouse / 石灰化 / OPLL / ttw / osteolysis / 遺伝子導入 / klotho / osteoporosis / インスリン / 骨吸収 / Runx2 / 軟骨内骨化 / p63 / SOX6 / 骨折治癒 / siRNA / Akt / 転写因子 / SNX19 / S100B / S100A1 / SOX9 / アポトーシス / Glutathione S-transferase P1 / COPD / biomaterial / バイオマテリアル / regenerative medicine / 人工関節 / SOX / polymer / DNA / 高分子 / chondrocyte / 炎症 / EP4 agonist / MyD88 / 脂肪 / polymorphism / cytatin 10 / nucleotide pyrophosphatase(NPPS) / ポリモルフィズム / 骨髄 / PPARγ / 弛み / ageing / 遺伝子解析 / Klotho / insulin / IGF-I / 骨折 / 再生 / IRS / IGF / bone resorption / 再生医学 / 関節炎 / バイオテクノロジー / ナノバイオ / 生体材料 / 遺伝子 / 軟骨代謝 / 分子生物学 / 遺伝子改変マウス / 関節軟骨 / 骨再生 / BMP / 骨分化 / Sox9 / 成長板 / cGKII / 遺伝子欠損マウス / 内軟骨性骨化 / 増殖 / 分化 / マウス / Osteoporosis / lipid / Adiponectin / トランスジェニックマウス / アディポネクチン / Transcription Factor / Joint Development / Cartilage Metabolism / ATX / HMG / GDF5 / WNT9A / 転写制御 / 関節再生 / 骨軟骨代謝学 / a high molecular material / polymer hydrogel / biocompatibility / anti-adhesion material / tendon injury / surgery / 高分子材料 / ハイドロポリマーゲル / 生体適合性 / 癒着防止材 / 腱損傷 / 手術 / gene transfer / fibroblasts / differentiation signal / bone formation / 線維芽細胞 / 分化シグナル / polyplex micelle / bone and joint disease / nanocarrier / delivery system / 高分子ミセル / 骨軟骨疾患 / ナノキャリア / デリバリーシステム / Apoptosis / Knockout mouse / Osteoclast / Osteoblast / Bone mineral density / Bone / 骨密度 / differentiation / proliferation / 3D culture / soluble factor / hydrogel / tissue engineering / 三次元培養 / 液性因子 / ハイドロゲル / Chondrogenic differentiation / ATDC5 / S100 / マイクロアレイ / SOXトリオ / レトロウィルスcDNAライブラリー / II型コラーゲン / ノッチシグナル / apoptosis / Adenovirus vector / chronic tabacco exposure / klotho gene / Gene Therapy / グルタチオンSトランスフェラーゼ / 肺気腫 / 慢性閉塞性肺疾患(COPD) / アデノウイルスベクター / 慢性喫煙 / Klotho遺伝子 / 遺伝子治療 / culture methods / optimal differentiation condition / chondrocyte differentiation / osteoblast differentiation / embryonic stem (ES) cells / 胚性幹細胞(ES) / 幹細胞 / 分化誘導 / 胚性幹細胞 / 培養方法 / 分化十分条件 / 胚性幹(ES)細胞 / aseptic loosening / artificial joint / cartilage / genomic epidemiology / carminerin / cyctatin10 / Sox / Runx2(cbfal) / fractional factorial design / ゲノム疫学 / Carminerin / block copolymer / confocal microscopy / fluorescence resonance energy transfer / PIC micelle / gene delivery / 遺伝子ベクター / ブロック共重合体 / レーザー共焦点顕微鏡 / 蛍光エネルギー移動 / ミセル / fracture / calcification / bone turnover / bone growth / 遺伝子組み換え / 異所性骨化 / 異所性石灰化 / cystain10 / 骨成長 / 遺伝子操作マウス / fracture repair / arthritis / prostaglandin / サイクロオキシナーゼ / サイクロオキシグナーゼ / 疼痛 / プロスタグラジン / プロスタグランジン / Laser / Dental pulp / Coupling factor / Bone resorption / Bone formation / Calcification / 急速凍結法 / EP4 / OPG / レーザー / プロスタグランジンE2 / カップリング因子 / PPAR-γ / ES細胞 / ヌクレオチドピロリン酸(NPPS) / SNP / ヌクレオチドピロフォスファターゼ(NPPS) / ヌクレオチドピロフォスファターゼ(NppS) / 後縦靭帯骨化症(OPLL) / cystatin10 / ttwマウス / ヌクレオチドピロフォスファターゼ / 脂肪細胞 / molecular and cellular biology / radiodense / rat / Pistraction osteogenesis / 生化学 / 組織学 / 顎矯正力 / 骨延長 / 下顎骨 / 新生骨の形成 / ラット / 骨延長法 / loosening / total hip arthroplasty / Biomaterials / サイトカイン / 骨融解 / 股関節シュミレーター / 人工股関節全置換術 / 股関節 / 2-メタクリロイルオキシエチルホスホリルコリン(MPC) / オステオライシス / 人工股関節 / muscle / nerve / spine / gene analysis / 網膜 / 筋肉 / 神経 / 脊髄 / osteoblast / IRS-1,-2 / MAP kinase / osteoclast / fibroblast growth factor / 成長因子 / fibroblast growth factor -2 / MAPキナーゼ / fibvoblast grouth factov-2 / 骨巨細胞腫 / 骨・軟部腫瘍 / NF-kBシグナル / 整形外科学 / 細胞分化 / クロマチン免疫沈降法 / 細胞周期 / 中枢神経系 / 免疫原性 / 神経障害 / ナノミセル / DDS / mRNA / Notchシグナル / 永久関節軟骨再生 / 関節病学 / EBPファミリー / C / C/EBPファミリー / 軟骨代謝学 / 骨・軟骨代謝 / 副甲状腺ホルモン / 骨軟骨代謝 / 細胞・組織 / 外傷治療 / 骨格筋 / 外傷 / ナノ材料 / GSK3β / トランスレーショナルリサーチ / 医療・福祉 / 疫学 / 画像解析 / 疾患モデル動物 / 骨・軟骨代謝学 / 力学的負荷 / 細胞外基質 / 蛋白分解酵素処理 / コラーゲンフィルム / 骨髄間葉系細胞 / 温度感受性培養皿 / 軟骨再生 / 細胞シート / cyclic GMP / KLF5 / 生理機能 / Bone morphogenetic protein / SOX5 / CILP / アンドロゲン / エストロゲン / グルココルチコイド / アンドロゲン受容体 / エストロゲン受容体 / 転写共役因子 / 男性ホルモン / 性ステロイドホルモン / 成長障害 / cGK2 / 成長軟骨板 / 連鎖解析 / 原因遺伝子 / KMIラット / 腱断裂 / 病理 / SKGマウス / カテプシンK / 酒石酸抵抗性酸性ホスファターゼ / 腱 / 関節リウマチ / Fracture / Environment / Asia / 大腿骨頚部骨折 / 環境因子 Less
  • Research Projects

    (62 results)
  • Research Products

    (715 results)
  • Co-Researchers

    (112 People)
  •  Strategic research of osteoarthritis for novel therapeuticsPrincipal Investigator

    • Principal Investigator
      Kawaguchi Hiroshi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Next Generation Sequencing of giant cell tumor of bone for the elucidation of pathology and the discovery of novel therapeutic target

    • Principal Investigator
      Tanaka Takeyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Autophagy mechanism in cartilage chonsrocytes.Principal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Development of in vivo mRNA delivery system for treating diseases

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanism of bone metabolism controlled by Cdk6 transcription factory

    • Principal Investigator
      OGASAWARA Toru
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  Analyses of IKK signaling pathway in locomotive diseases

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research of Notch signal in pathophysiology and therapeutics of osteoarthritis

    • Principal Investigator
      CHIKUDA Hirotaka
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Stud aiming at elucidating the molecular mechanism behind spondylosis through establishing cre / lox P system in the field of intervertebral disc.Principal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic research for elucidation of molecular pathophysiology and identification of therapeutic target of lumbar spondylosisPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  A novel approach to treat severe trauma using gene introduction by nanomicelle into skeletal muscle

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.

    • Principal Investigator
      OGATA Naoshi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Regulation of chondrocyte metabolism by transcription factor C/EBP families

    • Principal Investigator
      MIURA Toshiki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms of joint formation by transcription factor SOX11

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  甲状腺ホルモンおよび関連転写因子Pax8による軟骨代謝調節に関する挑戦的研究Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms of regulation in bone and cartilage metabolism by GSK3β

    • Principal Investigator
      CHIKUDA Hirotaka
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      国立障害者リハビリテーションセンター(研究所)
      The University of Tokyo
  •  The basic study of the effect of biocompatible phospholipid polymer on the osteoarthritis progression

    • Principal Investigator
      MORO Toru
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research of the Molecular Network Regulating Endochondral OssificationPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms of cartilage degeneration by mechanical stress

    • Principal Investigator
      HOSHI Kazuto, 星地 亜都司
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  老化抑制遺伝子Klothoの発現調節に関する萌芽的研究Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  軟骨内骨化制御因子cGK2の分子シグナルの解明と骨軟骨再生医療に向けての機能解析

    • Principal Investigator
      MURAKAMI Motoaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  細胞シート工学の骨・軟骨再生医療への応用のための基礎的研究

    • Principal Investigator
      SEICHI Atsushi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The elucidation of regulation of Bone Metabolism by Akt1

    • Principal Investigator
      HARA Yukinori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Interaction of signals between klotho and insulin in ageing and the related disorders

    • Principal Investigator
      KARITA Tatsuro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Development of multi-functional nanocarrier of siDNA and application for bone and joint diseases

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Identification of the minimal and sufficient signaling unit for bone formation and development of bone system using skin fibroblasts

    • Principal Investigator
      MORI Yoshiyuki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  Experimental study of tendon adhesion prevention by a biocompatible polymer hydrogel.

    • Principal Investigator
      MORO Toru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Expression Cloning of Joint Regenerative Genes

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
      The University of Tokyo
  •  Regulation of Bone Formation by Adiponectin

    • Principal Investigator
      MATSUDAIRA Ko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  変形性関節症で誘導される軟骨特異的遺伝子CILPのプロモーター解析

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  生理的骨形成に関与するBMPの同定とその臨床応用に関する研究

    • Principal Investigator
      鄭 雄一
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  新規転写因子KLF5による骨代謝調節機構の解明

    • Principal Investigator
      中村 耕三
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  細胞周期関連分子CDK6の生体内における骨・軟骨代謝調節機構の解明Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic Research for Upstream Molecules, Target molecules and Co-factors of the SOX trio, the Essential Transcription Factors for Chondrogenesis

    • Principal Investigator
      IKEDA Toshiyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research and Development for Fabrication of 3D-structured Tissue-engineered Cartilage through Nino-molecular Technologies

    • Principal Investigator
      HOSHI Kazuto
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  アンドロゲンシグナルによる骨代謝調節機構の解明

    • Principal Investigator
      KAWANO Hirotaka
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  新規軟骨分化制御因子cGK2シグナルの骨再正における機能解析とその標的分子の同定

    • Principal Investigator
      CHIKUDA Hirotaka
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  ステロイド受容体転写共役因子SRC-1による骨代謝調節機構の解明

    • Principal Investigator
      加藤 茂明, 河野 博隆
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research on Pathophysiology and Novel Treatment of Osteoarthritis through Molecular Biological Approach

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Inhibition of aseptic loosening of artificial joints by graft polymerizaiton of a novel biocompatible polymer MPC

    • Principal Investigator
      TAKATORI Yoshio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Elucidation of molecular mechanism involved in mechanical stress signaling in bone - functional analysis, contribution to pathology, and cloning of related molecule of a novel gene Znt5 -Principal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic study on osteoblast and chondrocyte differentiation from embryonic stem (ES) cells

    • Principal Investigator
      CHUNG Ung-il
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Experimental approach for gene therapy of pulmonary emphysema focusing on Klotho gene and GSTP1 gene

    • Principal Investigator
      TERAMOTO Shinji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      The University of Tokyo
  •  慢性関節リウマチにおける腱断裂機序の解明と治療法の確立

    • Principal Investigator
      YAMAMOTO Motoi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  細胞周期関連分子CDK6による骨・軟骨細胞分化制御機構に関する基礎的研究Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  MRIラットにおける軟骨異常病態の解明とその原因遺伝子の同定

    • Principal Investigator
      中村 耕三
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Analysis of molecular mechanisms in bone formation and regeneration

    • Principal Investigator
      OZAWA Hidehiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Contribution of new prostaglandin E_2 synthase to bone resorptive pathology and clinical application of PGES inhibitor

    • Principal Investigator
      YAMAMOTO Motoi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Study of the function of cystatin 10, a novel chondrocyte-specific gene.

    • Principal Investigator
      TAKESHITA Katsushi, 阿久根 徹, 佐藤 和強
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Development of PIG micelle vector system for gene delivery

    • Principal Investigator
      HOSHI Kazuto
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Regulation of bona and cartilage metabolism by nucleotide pyrophosphatase (NPPS) -skeletal analysis of ttw mice and its contribution to the human npps gene SNPs -

    • Principal Investigator
      TAKESHITA Katsushi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Regulation of bone and cartilage metabolism by nucleotide pyrophosphatase (NPPS) -skeletal analysis of ttw mice and its contribution to the human npps gene SNPs -

    • Principal Investigator
      NAKAGAWA Takumi, 五嶋 孝博
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  老化関連骨軟骨疾患におけるklotho遺伝子の関与Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  人工ウイルス(高分子ミセル型ベクター)を用いた細胞内遺伝子導入法の確立Principal Investigator

    • Principal Investigator
      川口 浩
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Involvement of the aging-suppressor gene klotho in the skeletal

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Mechanism of regulation of bone and cartilage metabolism by fibroblast growth factor-18 (FGF-18)Principal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Prevention of the total hip arthroplasty loosening polyethylene liner coated with MPC polymer

    • Principal Investigator
      SATOH Wakyo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular and Cellular biglogical study on the maxillotacial bone formation by orthognathic torce.

    • Principal Investigator
      SUSAMI Takafumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      The University of Tokyo
  •  Mechanism of regulation of bone metabolism by insulin receptor substrates (IRS-1 and IRS-2)

    • Principal Investigator
      KONO Shinjiro, 東 成一, 小崎 慶介
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Mechanism of bone resorption by fibroblast growth factor-2

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  アジア地域での生活環境が骨粗鬆症・骨粗鬆症関連骨折発生に及ぼす影響

    • Principal Investigator
      NAKAMURA Kozo, 黒川 高秀
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Stimulatory effects of fibroblast growth facor-2 on bone formation and bone resorptionPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] 変形性関節症の分子メカニズム-治療標的分子の同定を目指して-医学の歩み2011

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 関節・軟骨疾患の分子医学:変形性関節症の治療標的分子の探索(BIO CLINICA)((特集:骨・軟骨疾患の分子医学) 25(1))2010

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Book] 関節・軟骨疾患の分子医学 : 変形性関節症の治療標的分子の探索. BIO CLINICA (特集 : 骨・軟骨疾患の分子医学)2010

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 整形外科専門医テキスト2010

    • Author(s)
      川口浩
    • Total Pages
      985
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 整形外科専門医テキスト2010

    • Author(s)
      川口浩, ら
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Book] 整形外科専門医テキスト2010

    • Author(s)
      川口浩, ら
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Book] 変形性関節症の治療ガイドライン. Geriatric Medicine 老年医学 (特集 : 変形性関節症・脊椎症)-診断と治療の最前線-2010

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 遺伝子変異マウスによる変形性関節症の病態解明へのアプローチ(The Bone)((特集:変形性関節症の基礎と臨床) 23(1))2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Book] 遺伝子変異マウスによる変形性関節症の病態解明へのアプローチ. The Bone (特集 : 変形性関節症の基礎と臨床)2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 変形性関節症の疫学研究の現状と問題点 : ROAD (Research on Osteoarthritis Against Disability) 研究. 日本整形外科学会雑誌 (シンポジウム : 変形性膝関節症のマネージメント-最新の臨床エビデンスとエキスパートオピニオン-)2009

    • Author(s)
      川口浩, 阿久根徹, 村木重之, 岡敬之, 中村耕三, 吉村典子
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 変形性関節症に対する分子標的治療の展望. CLINICAL CALCIUM (特集 : 変形性関節症 Up-to-date)2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 変形性関節症における軟骨破壊のメカニズム(Osteovisual)(Arthritis 16(3))2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Book] 変形性関節症:研究・診療の現状と問題点(日本老年病学会雑誌)((骨粗鬆症と変形性関節症:研究と診療の最前線) 46(2))2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Book] 変形性関節症 : 研究・診療の現状と問題点. 日本老年病学会雑誌 (骨粗鬆症と変形性関節症 : 研究と診療の最前線)2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] Osteovisual「変形性関節症における軟骨破壊のメカニズム」. Arthritis2009

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] Molecules & Cells2008

    • Author(s)
      Hiroshi Kawaguchi
    • Total Pages
      252
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Book] 変形性関節症の治療標的分子の解明(骨のremodelingにおけるDickkopf-1の役割)(リウマチ科(特集:変形性関節症の病態と治療 -最近の進歩) 39(6))2008

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Book] 変形性関節症の治療標的分子の解明. 骨の remodeling における Dickkopf-1 の役割. リウマチ科 (特集 : 変形性関節症の病態と治療-最近の進歩)2008

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 世界におけるOAの疫学. Osteoarthritis Update (特集 : 変形性関節症の最新知見)2008

    • Author(s)
      村木重之, 川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 軟骨のメカニカルストレスと変形性関節症. CLINICAL CALCIUM (特集 : メカニカルストレスと骨)2008

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] OARSIによる股・膝関節OAの治療ガイドライン. Osteoarthritis Update (特集 : 変形性関節症の最新知見)2008

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] OAの画像診断. Osteoarthritis Update (特集 : 変形性関節症の最新知見)2008

    • Author(s)
      岡敬之, 川口浩
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 運動器リハビリテーションクルズス2008

    • Author(s)
      川口浩
    • Total Pages
      443
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] Molecules&Cells2008

    • Author(s)
      Hiroshi Kawaguchi
    • Total Pages
      252
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 変形性関節症 : ROAD 研究が明らかにした実態. 日経メディカル (特集 : 骨粗鬆症と運動器不安定症)2008

    • Author(s)
      川口浩, 阿久根徹, 岡敬之, 村木重之, 中村耕三, 吉村典子
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 「運動器リハビリテーションクルズス」第1章 運動を司る構造と機能 : 解剖・生理について. I. 筋骨格系骨. 1. 骨の構造と機能(編集 : 岩谷力、黒沢尚、江藤文夫、赤居正美、星野雄一、飛松好子)2008

    • Author(s)
      川口浩
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] 運動器リハビリテーションクルズス2008

    • Author(s)
      川口浩
    • Total Pages
      443
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-18659436
  • [Book] 変形性関節症の疫学研究. 日本整形外科学会雑誌 (シンポジウム : 変形性関節症の病態解明・診断・治療の新世紀)2007

    • Author(s)
      吉村典子, 岡敬之, 村木重之, 馬淵昭彦, 延與良夫, 吉田宗人, 鈴木隆雄, 山本精三, 川口浩, 中村耕三
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Book] OPLL -Ossification of the Posterior Longitudinal Ligament - 2nd Edition(edited by K. Yonenobu, T. Nakamura, Y. Toyama. Springer-Verlag Tokyo)2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Total Pages
      1023
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Book] OPLL - Ossification of the Posterior Longitudinal Ligament - 2nd Edition (edited by K. Yonenobu, T. Nakamura, and Y. Toyama)2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Total Pages
      1023
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-18659436
  • [Book] OPLL-Ossification of the posterior Longitudinal Ligament -2nd Edition "edited by K. Yonenobu, Y. Nakamura, and Y. Toyama2006

    • Author(s)
      Hirohi Kawaguchi, et al.
    • Total Pages
      1023
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Book] OPLL-Ossification of the Posterior Longitudinal Ligament-2nd Edition. (edited by K. Yonenobu, T. Nakamura, and Y. Toyama)2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Total Pages
      1023
    • Publisher
      Springer-Verlag Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Book] OPLL - Ossification of the Posterior Longitudinal Ligament - 2nd Edition" edited by K. Yonenobu, T. Nakamura, and Y. Toyama2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Total Pages
      1023
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Book] OPLL - Ossification of the Posterior Longitudinal Ligament - 2nd Edition' edited by K. Yonenobu, T. Nakamura, and Y. Toyama2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Total Pages
      1023
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Book] 老年医学update 2005-20062005

    • Author(s)
      緒方直史、川口浩
    • Total Pages
      565
    • Publisher
      メディカルビュー
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Book] 「図解 再生医療工学」立石哲也、田中順三編集「骨の再生」2004

    • Author(s)
      松原全宏, 川口 浩, 高戸 毅, 中村耕三, 鄭 雄一
    • Publisher
      工業調査会
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Book] Illustrated Book : Reproduction in Medical Technology (Edited by Tateishi Tetsuya, Tanaka Junzo)2004

    • Author(s)
      Matsubara Hiroshi, Kawaguchi Hiroshi, Takatou Takeshi, Kozo Nakamura, Chung, Ung-il.
    • Publisher
      Bone Regeneration
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Book] インスリン・IGFと骨(CLINICAL CALCIUM)(特集:ホルモンと骨粗鬆症 UPDATE)19 (7): 1015-1025, 2009.

    • Author(s)
      川口浩
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.2017

    • Author(s)
      Taniguchi Y, Kawata M, Chang SH, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, and Saito T*
    • Journal Title

      Arthritis Rheumatol.

      Volume: 69 Issue: 3 Pages: 598-609

    • DOI

      10.1002/art.39976

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
  • [Journal Article] Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.2016

    • Author(s)
      Kobayashi H, Chang S, Mori D, Itoh S, Hirata M, Hosaka Y, Taniguchi Y, Okada K, Mori Y, Yano F, Chung U, Akiyama H, Kawaguchi H, Tanaka S, Saito T.
    • Journal Title

      Nat Commun

      Volume: 7 Issue: 1 Pages: 13336-13336

    • DOI

      10.1038/ncomms13336

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K18398, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
  • [Journal Article] Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: The third survey of the ROAD study.2016

    • Author(s)
      Kodama R, Muraki S, Oka H, Iidaka T, Teraguchi M, Kagotani R, Asai Y, Yoshida M, Morizaki Y, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Yoshimura N.
    • Journal Title

      Mod Rheumatol

      Volume: not yet

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Journal Article] <b>Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding pr</b><b>oteins </b>2015

    • Author(s)
      Okuma T, Hirata M, Yano F, Mori D, Kawaguchi H, Chung UI, Tanaka S, Saito T
    • Journal Title

      Biomed. Res.

      Volume: 36 Issue: 1 Pages: 21-29

    • DOI

      10.2220/biomedres.36.21

    • NAID

      130004903876

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-25713052
  • [Journal Article] Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.2015

    • Author(s)
      Sugita S, Taketomi S, Saito T, et al.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 112 Issue: 10 Pages: 3080-5

    • DOI

      10.1073/pnas.1419699112

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-25713052, KAKENHI-PROJECT-26713054
  • [Journal Article] Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study.2015

    • Author(s)
      Yoshimura N, Musaki S, Oka H, Tanaka S, Ogata T, Kawaguchi H, Akune T, Nakamura K
    • Journal Title

      J Orthop Sci

      Volume: 20 Issue: 5 Pages: 896-905

    • DOI

      10.1007/s00776-015-0741-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15219, KAKENHI-PROJECT-26670307, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25670293, KAKENHI-PROJECT-26293139, KAKENHI-PROJECT-26293329, KAKENHI-PROJECT-26293331
  • [Journal Article] Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: The ROAD study.2015

    • Author(s)
      Muraki S, Akune T, Teraguchi M, Kagotani R, Asai Y, Yoshida M, Tokimura F, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N
    • Journal Title

      BMC musculoskeltal disorders

      Volume: 16 Issue: 1 Pages: 305-305

    • DOI

      10.1186/s12891-015-0737-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670307, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25670293, KAKENHI-PROJECT-26293139, KAKENHI-PROJECT-26293329, KAKENHI-PROJECT-26293331
  • [Journal Article] Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling2014

    • Author(s)
      Mori Y, Saito T, Chang SH, Kobayashi H, Ladel CH, Guehring H, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 289 Pages: 10192-200

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling.2014

    • Author(s)
      Mori Y, Saito T, Chang SH, Kobayashi H, Ladel CH, Guehring H, Chung UI, Kawaguchi H.
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 14 Pages: 10192-200

    • DOI

      10.1074/jbc.m113.524090

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24390348, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330
  • [Journal Article] Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study.2014

    • Author(s)
      Muraki S, Akune T, En-Yo Y, Yoshida M, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N
    • Journal Title

      Mod Rheumatol

      Volume: 24 Issue: 2 Pages: 236-42

    • DOI

      10.3109/14397595.2013.854055

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25670293, KAKENHI-PROJECT-25670630, KAKENHI-PROJECT-26293139, KAKENHI-PROJECT-26293331
  • [Journal Article] SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.2014

    • Author(s)
      Fujiwara S, Hoshikawa S, Ueno T, Hirata M, Saito T, Ikeda T, Kawaguchi H, Nakamura K, Tanaka S, Ogata T
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 12 Pages: e115400-e115400

    • DOI

      10.1371/journal.pone.0115400

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-26293330
  • [Journal Article] Transcriptional induction of ADAMTS5 by an NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2013

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 288 Pages: 28620-9

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Physical performance, bone and joint diseases, and incidence of falls in Japanese men and women: A longitudinal cohort study.2013

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoporosis Int

      Volume: 24 Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.2013

    • Author(s)
      Yano F, Kawaguchi H, et al.
    • Journal Title

      Ann Rheum Dis

      Volume: 72 Pages: 748-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Cell-sheet technology combined with a thienoindazole derivative small comnound TD-198946 for cartilage regeneration2013

    • Author(s)
      Yano F, Hojo H, et al.
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 22 Pages: 5581-5587

    • DOI

      10.1016/j.biomaterials.2013.04.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04835, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25713052
  • [Journal Article] β-catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region2013

    • Author(s)
      Yano F, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 65 Pages: 429-435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] ss-catenin regulates parathyroidhormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor2013

    • Author(s)
      Yano F, Saito T, Ogata N, Yamazawa T,Iino M, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 65 Pages: 429-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390416
  • [Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.2013

    • Author(s)
      Yano F, Kawaguchi H, et al.
    • Journal Title

      Ann Rheum Dis

      Volume: 72 Pages: 748-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium2013

    • Author(s)
      Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI.
    • Journal Title

      J Biol Chem

      Volume: 288 Pages: 9924-32

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration2013

    • Author(s)
      Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      Biomaterials

      Volume: 34 Pages: 5581-7

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] ss-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor2013

    • Author(s)
      Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 65(2) Pages: 429-35

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein(BMP) signaling.2013

    • Author(s)
      Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, and Hoshi K
    • Journal Title

      J Cell Physiol

      Volume: (in press) Issue: 1 Pages: 163-71

    • DOI

      10.1002/jcp.24116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-22659365, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-23592913, KAKENHI-PROJECT-23659938, KAKENHI-PROJECT-24390451, KAKENHI-PROJECT-24593050, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25670847
  • [Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx12013

    • Author(s)
      Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      Ann Rheum Dis

      Volume: 72 Pages: 748-53

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development2013

    • Author(s)
      Hosaka Y, Saito T, Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 110(5) Pages: 1875-80

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highlycross-linked polyethylene liner in primary total hip replacement: One-year results of a prospective cohort study.2013

    • Author(s)
      Takatori Y, Moro T, Kamogawa M, Oda H, Morimoto S, Umeyama T, Minami M, Sugimoto H, Nakamura S, Karita T, Kim J, Koyama Y, Ito H, Kawaguchi H, and Nakamura K
    • Journal Title

      J Artif Organs

      Volume: (in press) Issue: 2 Pages: 170-175

    • DOI

      10.1007/s10047-012-0681-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-23300175, KAKENHI-PROJECT-23390359
  • [Journal Article] Generation of Col2a1-EGFP-iPS cells for monitoring chondrogenic differentiation2013

    • Author(s)
      Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE

      Volume: 8

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Physical performance, bone and joint diseases, and incidence of falls in Japanese men and women: A longitudinal cohort study.2013

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoporosis Int

      Volume: 24 Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] β-catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region2013

    • Author(s)
      Yano F, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 65 Pages: 429-435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morp hogenetic protein toward osteogenesis in the perichondrium.2013

    • Author(s)
      Hojo H, et al.
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 14 Pages: 9924-9932

    • DOI

      10.1074/jbc.m112.409342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04835, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
  • [Journal Article] Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation2013

    • Author(s)
      Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
    • Journal Title

      PLoS One

      Volume: 16;8(9) Issue: 9 Pages: e74137-e74137

    • DOI

      10.1371/journal.pone.0074137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689052, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
  • [Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.2013

    • Author(s)
      Hosaka Y, Kawaguchi H, et al.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 110 Pages: 1875-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Journal Article] β-catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region2013

    • Author(s)
      Yano F, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 65 Pages: 429-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Journal Article] Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.2013

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H.
    • Journal Title

      J Biol Chem.

      Volume: 288 Issue: 40 Pages: 28620-9

    • DOI

      10.1074/jbc.m113.452169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659663, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670634
  • [Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development2013

    • Author(s)
      Hosaka Y, Saito T (equally contributed), Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 110 Pages: 1875-80

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] β-catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region2013

    • Author(s)
      Yano F, Saito T (equally contributed), Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 65 Pages: 429-35

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-23

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] C/EBPβand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2a as the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kawaguchi H, et al
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum-US

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] C/EBPβ and EUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] C/EBPss and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21(5) Pages: 1111-23

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Does mild cognitive impairment affect the occurrence of radiographic knee osteoarthritis? A 3-year follow-up in the ROAD study.2012

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Tanaka S, and Akune T
    • Journal Title

      BMJ Open (in press)

      Volume: 2 Issue: 6 Pages: 2001520-2001520

    • DOI

      10.1136/bmjopen-2012-001520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-23390172, KAKENHI-PROJECT-23390357, KAKENHI-PROJECT-23659580, KAKENHI-PROJECT-24659317
  • [Journal Article] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study2012

    • Author(s)
      Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 20(10) Pages: 1103-8

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery : analysis of a national administrative database in Japan2012

    • Author(s)
      Chikuda H, Yasunaga H, Horiguchi H, Takeshita K, Kawaguchi H, Matsuda S, Nakamura K
    • Journal Title

      J Bone Joint Surg Am

      Volume: 94(5) Pages: 433-8

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] GSK-3α and GSK-3ss proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation2012

    • Author(s)
      Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algul H, Schmid RM, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 287(35) Pages: 29227-36

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Incidence and risk factors for radiographic lumbar spondylosis and lower back pain in Japanese men and women: The ROAD study.2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoarthr Cartilage

      Volume: 20 Pages: 712-718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women: A longitudinal population-based cohort study.2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 1447-1456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-203

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 64(1) Pages: 198-203

    • Data Source
      KAKENHI-PROJECT-23659706
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women : A longitudinal population-based cohort study2012

    • Author(s)
      Muraki S, Kawaguchi H, et al
    • Journal Title

      Arthritis Rheum

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Incidenceand risk factors for radiographic lumbar spondylosis and lower back pain in Japanese men and women: The ROAD study.2012

    • Author(s)
      Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Osteoarthr Cartilage

      Volume: 20 Pages: 712-718

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] GSK-3α and GSK-3β are involved in early stages of chondrocyte differentiation with functional redundancy through RelA phosphorylation.2012

    • Author(s)
      Itoh S, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 29227-28236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: The Wakayama Spine Study.2012

    • Author(s)
      Ishimoto Y, Kawaguchi H, et al.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 20 Pages: 1103-1108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H:
    • Journal Title

      Arthritis Rheum-US

      Volume: 64 Pages: 198-203

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Incidence and risk factors for radiographic lumbar spondylosis and lower back pain in Japanese men and women: The ROAD study.2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoarthr Cartilage

      Volume: 20 Pages: 712-718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women: A longitudinal population-based cohort study.2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 1447-1456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] C/EBP-β and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.2012

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women : A longitudinal population-based cohort study2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: (E-pub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] C/EBPβand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification2012

    • Author(s)
      Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 17860-9

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation2012

    • Author(s)
      Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algül H, Schmid RM, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 29227-36

    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Physical performance, bone and joint diseases, and incidence of falls in Japanese men and women2012

    • Author(s)
      Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      A longitudinal cohort study. Osteoporosis Int (inpress)

      Volume: 21(Epub ahead of print) Issue: 2 Pages: 459-466

    • DOI

      10.1007/s00198-012-1967-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-22591698, KAKENHI-PROJECT-23390172, KAKENHI-PROJECT-23390356, KAKENHI-PROJECT-23390357, KAKENHI-PROJECT-23659580, KAKENHI-PROJECT-24659317, KAKENHI-PROJECT-24659666
  • [Journal Article] Gli1 participates in the hedgehog-mediated specification of the osteoblast lineage during endochondralossification.2012

    • Author(s)
      Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, and Ung-il Chung
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 17860-17869

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in apopulation-based cohort in Japan: The Wakayama Spine Study.2012

    • Author(s)
      Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, OkaH, Kawaguchi H, Nakamura K, Akune T, Yoshida M
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 20 Pages: 1103-1108

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum-US

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBP-βand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] SP7 inhibits osteoblast differentiation at a latestage in mice.2012

    • Author(s)
      Yoshida CA, Komori H, Maruyama Z, Miyazaki T, Kawasaki K, Furuichi T, Fukuyama R, Mori M, Yamana K, Nakamura K, Liu W, Toyosawa S, MoriishiT, Kawaguchi H, Takada K, Komori T
    • Journal Title

      PLoS ONE

      Volume: 7

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kawaguchi H, et al
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] C/EBP-β and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.2012

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Incidenceand risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women: A longitudinal population-based cohort study.2012

    • Author(s)
      Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Arthritis Rheum-US

      Volume: 64 Pages: 1447-1456

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] GSK-3α and GSK-3β are involved in early stages of chondrocyte differentiation with functional redundancy through RelA phosphorylation.2012

    • Author(s)
      Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algul H, Schmid RM, Chung UI, and Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 29227-29236

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women : A longitudinal population-based cohort study2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: (E-pub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Prevalence of cervical cord compression and its association with physical performance in a population-based cohort in Japan: The Wakayama Spine Study.2012

    • Author(s)
      Nagata K, Kawaguchi H, et al.
    • Journal Title

      Spine

      Volume: 37 Pages: 1892-1898

    • NAID

      10031169860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: The Wakayama Spine Study.2012

    • Author(s)
      Ishimoto Y, Kawaguchi H, et al.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 20 Pages: 1103-1108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] C/EBP-β and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as theinducer in chondrocytes.2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and,HIF-2α as the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012

    • Author(s)
      Fukai A, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Biomimetic hydration lubrication with various polyelectrolyte layers on cross-linked polyethylene orthopedic bearing materials.2012

    • Author(s)
      Kyomoto M, Moro T, Saiga K, Hashimoto M, Ito H, Kawaguchi H, Takatori Y, Ishihara K
    • Journal Title

      Biomaterials

      Volume: 33 Pages: 4451-4459

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Incidence and risk factors for radiographic knee osteoarthritis and knee pain in Japanese men and women : A longitudinal population-based cohort study2012

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Prevalence of cervical cord compression and its association with physical performance in a population-based cohort in Japan: The Wakayama Spine Study.2012

    • Author(s)
      Nagata K, Kawaguchi H, et al.
    • Journal Title

      Spine

      Volume: 37 Pages: 1892-1898

    • NAID

      10031169860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012

    • Author(s)
      Fukai A, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Independent association of joint space narrowing and osteophyte formation at the knee with health-related quality of life in Japan : a cross-sectional study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 63 Pages: 3859-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Association of Knee Osteoarthritis with the Accumulation of Metabolic Risk Factors Such as Overweight, Hypertension, Dyslipidemia, and Impaired Glucose Tolerance in Japanese Men and Women : The ROAD Study.2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Rheumatol.

      Volume: (Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Prevalence of falls and the association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Care Res

      Volume: 63 Pages: 1425-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.2011

    • Author(s)
      Ishiyama N, Kawaguchi H, et al.
    • Journal Title

      J Bone Joint Surg Am.

      Volume: 93 Pages: 142-149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Biochemical markers of bone turnover as predictors of osteoporosis and osteoporotic fractures in men and women : 10-year follow-up of the Taiji cohort2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      Mod Rheumatol

      Volume: 21 Pages: 608-20

    • NAID

      10030206069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone2011

    • Author(s)
      Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390416
  • [Journal Article] Prevalence of falls and the association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Care Res

      Volume: 63 Pages: 1425-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Association of Occupational Activity with Joint Space Narrowing and Osteophytosis in the Medial Compartment of the Knee : The ROAD study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: (Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Independent association of joint space narrowing and osteophyte formation at the knee with health-related quality of life in Japan : a cross-sectional study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 63 Pages: 3859-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Changes in serum levels of biochemical markers of bone turnover durihg 10 years among Japanese men and women : associated factors and birth-cohort effect. The Taiji Study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 29 Pages: 699-708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Capacity of endogenous sex steroids to predict bone loss in Japanese men : 10-year follow-up of the Taiji Cohort Study.2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 29 Pages: 96-102

    • NAID

      10029023846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Capacity of endogenous sex steroids to predict bone loss in Japanese men : 10-year follow-up of the Taiji Cohort Study.2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 29 Pages: 96-102

    • NAID

      10029023846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability : the second survey of the ROAD study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Orthop Sci

      Volume: 16 Pages: 768-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Independent association of joint space narrowing and osteophyte formation at the knee with health-related quality of life in Japan : a cross-sectional study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Rheum

      Volume: 63 Pages: 3859-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Changes in serum levels of biochemical markers of bone turnover during 10 years among Japanese men and women : associated factors and birth-cohort effect. The Taiji Study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 29 Pages: 699-708

    • NAID

      10030895205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] The G&alphaq signal in osteoblasts is inhibitory to the osteoanabolic action of PTH.2011

    • Author(s)
      Ogata N, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem.

      Volume: (Epub)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone2011

    • Author(s)
      Ogata N, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability : the second survey of the ROAD study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Orthop Sci

      Volume: 16 Pages: 768-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Biochemical markers of bone turnover as predictors of osteoporosis and osteoporotic fractures in men and women : 10-year follow-up of the Taiji cohort2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      Mod Rheumatol

      Volume: 21 Pages: 608-20

    • NAID

      10030206069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone2011

    • Author(s)
      Ogata N, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Association of Knee Osteoarthritis with the Accumulation of Metabolic Risk Factors Such as Overweight, Hypertension, Dyslipidemia, and Impaired Glucose Tolerance in Japanese Men and Women : The ROAD Study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Rheumatol.

      Volume: (Epub)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Changes in serum levels of biochemical markers of bone turnover during 10 years among Japanese men and women : associated factors and birth-cohort effect. The Taiji Study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 29 Pages: 699-708

    • NAID

      10030895205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Prevalence of falls and the association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Arthritis Care Res

      Volume: 63 Pages: 1425-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] The G&alpha ; q signal in osteoblasts is inhibitory to the osteoanabolic action of PTH.2011

    • Author(s)
      Ogata N, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem.

      Volume: (Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Biochemical markers of bone turnover as predictors of osteoporosis and osteoporotic fractures in men and women : 10-year follow-up of the Taiji cohort2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      Mod Rheumatol

      Volume: 21 Pages: 608-20

    • NAID

      10030206069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Association of Occupational Activity with Joint Space Narrowing and Osteophytosis in the Medial Compartment of the Knee : The ROAD study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: (Epub)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.2011

    • Author(s)
      Ishiyama N, Kawaguchi H, et al
    • Journal Title

      J Bone Joint Surg Am.

      Volume: 93 Pages: 142-149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone2011

    • Author(s)
      Ogata N, Kawaguchi H, et al.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability : the second survey of the ROAD study2011

    • Author(s)
      Yoshimura N, Kawaguchi H, et al.
    • Journal Title

      J Orthop Sci

      Volume: 16 Pages: 768-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Health-related quality of life in subjects with low back pain and knee pain in a population-based cohort study of Japanese men : the Research on Osteoarthritis Against Disability study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Spine

      Volume: 36 Pages: 1312-9

    • NAID

      10030716059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Health-related quality of life in subjects with low back pain and knee pain in a population-based cohort study of Japanese men : the Research on Osteoarthritis Against Disability study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Spine

      Volume: 36 Pages: 1312-9

    • NAID

      10030716059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] The Gαq signal in osteoblasts is inhibitory to the osteoanabolic action of PTH2011

    • Author(s)
      Ogata N, Shinoda Y, Wettschureck N, Offerman S, Takeda S, Nakamura K, Segre GV, Chung UI, and Kawaguchi H
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-13740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone2011

    • Author(s)
      Ogata N, Kawaguchi H, et al
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 13733-13733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Health-related quality of life in subjects with low back pain and knee pain in a population-based cohort study of Japanese men : the Research on Osteoarthritis Against Disability study2011

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Spine

      Volume: 36 Pages: 1312-9

    • NAID

      10030716059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Journal Article] Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates.2010

    • Author(s)
      Liu G, Iwata K, Ogasawara T, Watanabe J, Fukazawa K, Ishihara K, Asawa Y, Fujihara Y, Chung UI, Moro T, Takatori Y, Takato T, Nakamura K, Kawaguchi H, Hoshi K
    • Journal Title

      J Biomed Mater Res A (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010

    • Author(s)
      Saito T, Kawaguchi H, et al.
    • Journal Title

      Nat Med.

      Volume: 16 Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Runx1 and Runx2 cooperate during sternal morphogenesis.2010

    • Author(s)
      Ayako Kimura, Hiroshi Kawaguchi, et al
    • Journal Title

      Development 137

      Pages: 1159-1167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine)on poly(ether-ether-ketone).2010

    • Author(s)
      Masayuki Kyomoto, Hiroshi Kawaguchi, et al
    • Journal Title

      Biomaterials 31

      Pages: 1017-1024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system.2010

    • Author(s)
      Hojo H, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 28 Pages: 627-633

    • NAID

      10027845798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures : Arandomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Res.

      Volume: 25 Pages: 2459-2467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Akt1 in chondrocytes controls cartilage calcification during endochondral ossification under physiological and pathological conditions.2010

    • Author(s)
      Atsushi Fukai, Hiroshi Kawaguchi, et al
    • Journal Title

      Arthritis Rheum 62

      Pages: 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells.2010

    • Author(s)
      Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N
    • Journal Title

      J Cell Biochem 109

      Pages: 755-763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010

    • Author(s)
      Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, and Ogata N
    • Journal Title

      J Cell Biochem

      Volume: 109 Pages: 755-763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development2010

    • Author(s)
      Saito T, Kawaguchi H, et al
    • Journal Title

      Nat Med

      Volume: 16 Pages: 678-678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010

    • Author(s)
      Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N
    • Journal Title

      J Cell Biochem 109

      Pages: 755-763

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Normal and threshold values of radiographic parameters for knee osteo arthritis using a computer-assisted measuring system (KOACAD) : the ROAD study.2010

    • Author(s)
      Oka H, Kawaguchi H, et al.
    • Journal Title

      J Orthop Sci.

      Volume: 15 Pages: 781-789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] A local application of recombinant human fibroblast growth factor-2 for tibial shaft fractures: a randomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, Oka H, Jingushi S, Izumi T, Fukunaga M, Sato K, Matsushita T, Nakamura K
    • Journal Title

      J Bone Miner Res 25

      Pages: 2459-2467

    • NAID

      40019184270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates.2010

    • Author(s)
      G Liu, Hiroshi Kawaguchi, et al
    • Journal Title

      J Biomed Mater Res A 92A

      Pages: 1273-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 62 Pages: 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis development2010

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
    • Journal Title

      Nat Med

      Volume: 16 Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Impact of knee and low back pain on health-related quality of life in Japanese women : the Research on Osteoarthritis Against Disability(ROAD).2010

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Mod Rheumatol.

      Volume: 20 Pages: 444-451

    • NAID

      10027646934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Aktl in chondrocytes controls cartilage calcification during endochondral ossification under physiological and pathological conditions.2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Title : Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system.2010

    • Author(s)
      Hojo H, Yano F, Ohba S, Igawa K, Nakajima K, Komiyama Y, Kan A, Ikeda T, Yonezawa T, Woo JT, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      J Bone Miner Metab 28

      Pages: 627-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] A local application of recombinant human fibroblast growth factor 2 for tibial shaft fractures : A randomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Res.

      Volume: 25 Pages: 2459-67

    • NAID

      40019184270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development.2010

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Journal Title

      Nat Med 16

      Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] A local application of recombinant human fibroblast growth factor-2 for tibial shaft fractures : a randomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 25 Pages: 2459-2467

    • NAID

      40019184270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Aktl in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 62(3)

      Pages: 826-36

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine)on poly(ether-ether-ketone).2010

    • Author(s)
      Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K
    • Journal Title

      Biomaterials (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010

    • Author(s)
      Saito T, Kawaguchi H, et al.
    • Journal Title

      Nat Med.

      Volume: 16 Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Impact of knee and low back pain on health-related quality of life in Japanese women : the Research on Osteoarthritis Against Disability (ROAD).2010

    • Author(s)
      Muraki S, Kawaguchi H, et al.
    • Journal Title

      Mod Rheumatol.

      Volume: 20 Pages: 444-451

    • NAID

      10027646934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] Cohort profile : Research on Osteoarthritis/Osteoporosis Against Disability study2010

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, and Akune T
    • Journal Title

      Int J Epidemiol

      Volume: 39 Pages: 988-995

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010

    • Author(s)
      Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N.
    • Journal Title

      J Cell Biochem. 109(4)

      Pages: 755-63

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system.2010

    • Author(s)
      Hojo H, Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Metab.

      Volume: 28 Pages: 627-633

    • NAID

      10027845798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Journal Article] A local application of recombinant human fibroblast growth factor-2 for tibial shaft fractures : a randomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 25 Pages: 2459-2467

    • NAID

      40019184270

    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Normal and threshold values of radiographic parameters for knee osteo arthritis using a computer-assisted measuring system(KOACAD) : the ROAD study.2010

    • Author(s)
      Oka H, Kawaguchi H, et al.
    • Journal Title

      J Orthop Sci.

      Volume: 15 Pages: 781-789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 62 Pages: 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine) on poly(ether-ether-ketone)2010

    • Author(s)
      Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K
    • Journal Title

      Biomaterials 31 (6)

      Pages: 1017-1024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions.2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 62

      Pages: 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 62

      Pages: 826-836

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Cohort profile : Research on Osteoarthritis/Osteoporosis Against Disability study.2010

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
    • Journal Title

      Int J Epidemiol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] A local application of recombinant human fibroblast growth factor-2 for tibial shaft fractures : a randomized, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 25 Pages: 2459-2467

    • NAID

      40019184270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Journal Article] Runx1 and Runx2 cooperate during sternum morphogenesis.2010

    • Author(s)
      Kimura A, Inose H, Yano F, Fujita K, Ikeda T, Sato S, Iwasaki M, Jinno T, Ae K, Fukumoto S, Takeuchi Y, Itoh H, Imamura T, Kawaguchi H, Chung UI, Martin JF, Iseki S, Shinomiya K, Takeda S
    • Journal Title

      Development 137

      Pages: 1159-1167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis development2010

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
    • Journal Title

      Nat Med

      Volume: 16 Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] The prevention of peritendinous adhesions by a phosphlipid polymer hydrogel formed in situ by spontaneous intermolecular interactions.2010

    • Author(s)
      Noriyuki Ishiyama, Hiroshi Kawaguchi, et al
    • Journal Title

      Biomaterials 31

      Pages: 4009-4016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 166-178

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Prevalence of radiographic lumbar spondylosis and its association with low back pain in the elderly of population-based cohorts : the ROAD study.2009

    • Author(s)
      Shigeyuki Muraki, Hiroshi Kawaguchi, et al
    • Journal Title

      Ann Rheum Dis 68

      Pages: 1401-1406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates2009

    • Author(s)
      Liu G, Iwata K, Ogasawara T, Watanabe J, Fukazawa K, Ishihara K, Asawa Y, Fujihara Y, Chung UI, Moro T, Takatori Y, Takato T, Nakamura K, Kawaguchi H, Hoshi K
    • Journal Title

      J Biomed Mater Res A 92

      Pages: 1273-1282

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1065-1075

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporos is in Japanese men and women : the research on osteoarthritis/osteoporosis against disability study.2009

    • Author(s)
      Noriko Yoshimura, Hiroshi Kawaguchi, et al
    • Journal Title

      J Bone Miner Metab 27

      Pages: 620-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene.2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Cohort profile : Research on Osteoarthritis/Osteoporosis Against Disability study.2009

    • Author(s)
      Noriko Yoshimura, Hiroshi Kawaguchi, et al
    • Journal Title

      Int J Epidemiol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Regulation of osteoarthritis development by wnt-β-catenin signaling through the endochondral ossification process.2009

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res 24

      Pages: 8-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Effects of mobility/immobility of surface modification by 2-methacryloyloxyethyl phosphorylcholine polymer on the durability of polyethylene for artificial joints.2009

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Hashimoto M, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Journal Title

      J Biomed Mater Res A 90

      Pages: 362-371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Accelerated cartilage resorption by chondroclasts during bone fracture healing in osteoprotegerin-deficient mice2009

    • Author(s)
      Ota N, Takaishi H, Kosaki N, Takito J, Yoda M, Tohmonda T, Kimura T, Okada Y, Yasuda H, Kawaguchi H, Matsumoto M, Chiba K, Ikegami H, Toyama Y.
    • Journal Title

      Endocrinology 150(11)

      Pages: 4823-34

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum. 60(11)

      Pages: 3314-23

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Prevalence of radiographic lumbar spondylosis and its association with low back pain in the elderly of population-based cohorts : the ROAD study2009

    • Author(s)
      Muraki S, Oka H, Mabuchi A, Akune T, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Yamamoto S, Nakamura K, Kawaguchi H, and Yoshimura N
    • Journal Title

      Ann Rheum Dis

      Volume: 68 Pages: 1401-1406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Regulation of osteoarthritis development by Wnt-β-catenin signaling through the endochondral ossification process2009

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res 24

      Pages: 8-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 60 Pages: 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women : the research on osteoarthritis/osteoporosis against disability study.2009

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Mabuchi A, En-Yo Y, Yoshida M, Saika A, Yoshida H, Suzuki T, Yamamoto S, Ishibashi H, Kawaguchi H, Nakamura K, Akune T
    • Journal Title

      J Bone Miner Metab 27

      Pages: 628-620

    • NAID

      10027205889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chn ofondrocytes through transactivatiop57^<kip2>.2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasa wara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLOS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 60(1)

      Pages: 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] 変形性関節症:研究・診療の現状と問題点.2009

    • Author(s)
      川口浩
    • Journal Title

      日本老年病学会雑誌 46

      Pages: 121-127

    • NAID

      10024963985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts : A large-scale population-based study2009

    • Author(s)
      Muraki S, Akune T, Oka H, Mabuchi A, En-yo Y, Yoshida M, Saika A, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Arthritis Rheum 61

      Pages: 779-786

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Prevalence of radiographic lumbar spondylosis and its association with low back pain in the elderly of population-based cohorts : the ROAD study2009

    • Author(s)
      Muraki S, Oka H, Mabuchi A, Akune T, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Ann Rheum Dis 68

      Pages: 1401-1406

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.2009

    • Author(s)
      Kazuhito Morioka, Hiroshi Kawaguchi, et al
    • Journal Title

      Cancer Sci 100

      Pages: 1227-1233

    • NAID

      10027191977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of2009

    • Author(s)
      Hirata M, Ikeda T, Chung U, Kawaguchi H(その他9名)
    • Journal Title

      PLoS ONE 4

      Pages: 57-57

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Ikeda T, Chung U, Kawaguchi H (その他9名)
    • Journal Title

      Arthritis Rheum 60

      Pages: 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts : The ROAD study2009

    • Author(s)
      Muraki S, Oka H, Akune T, Mabuchi A, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1137-1143

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women : the research on osteoarthritis/osteoporosis against disability study2009

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Mabuchi A, En-Yo Y, Yoshida M, Saika A, Yoshida H, Suzuki T, Yamamoto S, Ishibashi H, Kawaguchi H, Nakamura K, Akune T
    • Journal Title

      J Bone Miner Metab 27

      Pages: 620-628

    • NAID

      10027205889

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts : A large-scale population-based study.2009

    • Author(s)
      Muraki S, Akune T, Oka H, Mabuchi A, En-yo Y, Yoshida M, Saika A, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Arthritis Rheum 61

      Pages: 779-786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Superlubricious surface mimicking articular cartilage by grafting poly(2-methacryloyloxyethyl phosphorylcholine)on orthopaedic metal bearings.2009

    • Author(s)
      Masayuki Kyomoto, Hiroshi Kawaguchi, et al
    • Journal Title

      J Biomed Mater Res A 91

      Pages: 730-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPβpromotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Osteovisual「変形性関節症における軟骨破壊のメカニズム」2009

    • Author(s)
      川口浩
    • Journal Title

      Arthritis 16

      Pages: 149-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Low dietary vitamin K intake is associated with radiographic knee osteoarthritis in the Japanese elderly : Dietary survey in a population-based cohort of the ROAD study.2009

    • Author(s)
      Hiroyuki Oka, Hiroshi Kawaguchi, et al
    • Journal Title

      J Orthop Sci 14

      Pages: 687-692

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] 遺伝子変異マウスによる変形性関節症の病態解明へのアプローチ.2009

    • Author(s)
      川口浩
    • Journal Title

      The Bone 23

      Pages: 35-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] 変形性関節症に対する分子標的治療の展望2009

    • Author(s)
      川口浩
    • Journal Title

      CLINICAL CALCIUM 19

      Pages: 1608-1614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts : A large-scale population-based study.2009

    • Author(s)
      Shigeyuki Muraki, Hiroshi Kawaguchi, et al
    • Journal Title

      Arthritis Rheum 61

      Pages: 779-786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Regulation of osteoarthritis development by Wnt-β-catenin signaling through the endochondral ossification process2009

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res

      Volume: 24 Pages: 8-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts : A large-scale population-based study2009

    • Author(s)
      Muraki S, Akune T, Oka H, Mabuchi A, En-yo Y, Yoshida M, Saika A, Nakamura K, Kawaguchi H, and Yoshimura N
    • Journal Title

      Arthritis Rheum

      Volume: 61 Pages: 779-786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>.2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts : The ROAD study.2009

    • Author(s)
      Shigeyuki Muraki, Hiroshi Kawaguchi, et al
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1137-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 60 Pages: 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor.2009

    • Author(s)
      Akinori Kan, Hiroshi Kawaguchi, et al
    • Journal Title

      Arthritis Rheum 60

      Pages: 3314-3323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells.2009

    • Author(s)
      Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1065-1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 3314-3323

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 60 Pages: 3314-3323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells.2009

    • Author(s)
      Masahiro Ushita, Hiroshi Kawaguchi, et al
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1065-1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts : The ROAD study.2009

    • Author(s)
      Muraki S, Oka H, Akune T, Mabuchi A, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1143-1137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Wear resistance of artificial hip joints with poly(2-methacryloyloxyethyl phosphorylcholine)grafted polyethylene : Comparisons with the effect of polyethylene cross-linking and ceramic femoral heads.2009

    • Author(s)
      Toru Moro, Hiroshi Kawaguchi, et al
    • Journal Title

      Biomaterials 30

      Pages: 2995-3001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 4

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Low dietary vitamin K intake is associated with radiographic knee osteoarthritis in the Japanese elderly : Dietary survey in a population-based cohort of the ROAD study2009

    • Author(s)
      Oka H, Akune T, Muraki S, Mabuchi A, En-yo Y, Yoshida M, Saika A, Sasaki S, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      J Orthop Sci 14

      Pages: 687-692

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Transcriptional induction of SOX9 by NF_<-κ> B family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, and Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 17 Pages: 1065-1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Journal Article] Regulation of osteoarthritis development by Wnt-β-catenin signaling through the endochondral ossification process.2009

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res 24

      Pages: 8-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor.2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 3314-3323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Lubricity and stability of poly(2-methacryloyloxyethyl phosphorylcholine)polymer layer on Co-Cr-Mo surface for hemi-arthroplasty to prevent degeneration of articular cartilage.2009

    • Author(s)
      Masayuki Kyomoto, Hiroshi Kawaguchi, et al
    • Journal Title

      Biomaterials 31

      Pages: 658-668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Epidemiology of lumbar osteoporosis and osteoarthritis and their causal relationship-Is osteoarthritis a predictor for osteoporosis or vice versa? : The Miyama study.2009

    • Author(s)
      Noriko Yoshimura, Hiroshi Kawaguchi, et al
    • Journal Title

      Osteoporosis Int 20

      Pages: 999-1008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPβpromotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Superlubricious surface mimicking articular cartilage by grafting poly(2-methacryloyloxyethyl phosphorylcholine)on orthopaedic metal bearings.2009

    • Author(s)
      Kyomoto M, Moro T, Iwasaki Y, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Journal Title

      J Biomed Mater Res A 91

      Pages: 741-730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Ikeda T, Chung U, Kawaguchi H(その他5名)
    • Journal Title

      Osteoarthritis Cartilage, E-pub

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts : a large-scale population-based study2009

    • Author(s)
      Muraki S, Akune T, Oka H, Mabuchi A, En-Yo Y, Yoshida M, Saika A, Nakamura K, Kawaguchi H, Yoshimura N.
    • Journal Title

      Arthritis Rheum 61(6)

      Pages: 779-86

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 4(2)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Effects of mobility/immobility of surface modification by 2-methacryloyloxyethyl phosphorylcholine polymer on the durability of polyethylene for artificial joints.2009

    • Author(s)
      Masayuki Kyomoto, Hiroshi Kawaguchi, et al
    • Journal Title

      J Biomed Mater Res A 90

      Pages: 362-371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Superlubricious surface mimicking articular cartilage by grafting poly(2-methacryloyloxyethyl phosphorylcholine) on orthopaedic metal bearings2009

    • Author(s)
      Kyomoto M, Moro T, Iwasaki Y, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Journal Title

      J Biomed Mater Res A 91 (3)

      Pages: 730-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Epidemiology of lumbar osteoporosis and osteoarthritis and their causal relationship-Is osteoarthritis a predictor for osteoporosis or vice versa?: The Miyama study2009

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kinoshita H, Yoshida M, Mabuchi A, Kawaguchi H, Nakamura K, Akune T
    • Journal Title

      Osteoporosis Int 20

      Pages: 999-1008

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Regulation of osteoarthritis development by Wnt-β-catenin signaling through the endochondral ossification process2009

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res 24

      Pages: 8-11

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Ikeda T, Chung U, KawaguchiH (その他14名)
    • Journal Title

      J Clin Invest 118

      Pages: 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Endochondral ossification signals in cartilage degradation during osteoarthritis progression in experimental mouse models2008

    • Author(s)
      Kawaguchi H
    • Journal Title

      Mol Cells 25

      Pages: 1-6

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Ikeda T, Chung U, Kawaguchi H (その他11名)
    • Journal Title

      Dev Cell 14

      Pages: 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] The Distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration : Findings in murine models and in human disease2008

    • Author(s)
      Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S
    • Journal Title

      Arthritis Rheum 58

      Pages: 2764-2775

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration : findings in murine models and in human disease2008

    • Author(s)
      Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S.
    • Journal Title

      Arthritis Rheum. 58(9)

      Pages: 2764-75

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Clin Invest 118(7)

      Pages: 2506-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem 283(36)

      Pages: 24682-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem 283

      Pages: 24682-24689

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Clin Invest. 118(7)

      Pages: 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders2008

    • Author(s)
      Yamakawa K, Kamekura S, Kawamura N, Saegusa M, Kamei D, Murakami M, Kudo I, Uematsu S, Akira S, Chung UI, Nakamura K, Kawaguchi H.
    • Journal Title

      Arthritis Rheum. 58(1)

      Pages: 172-83

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Fully automatic quantification of knee osteoarthritis severity on plain radiographs2008

    • Author(s)
      Oka H, Muraki S, Akune T, Mabuchi A, Suzuki T, Yoshida H, Yamamoto S, Nakamura K, Yoshimura N, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 16

      Pages: 1300-1306

    • NAID

      40020243882

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI
    • Journal Title

      Dev Cell 14

      Pages: 689-699

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcriptional activator.2008

    • Author(s)
      Tamiya H, Ikeda T, Jung JH, Saito T, Jung YK, Kawaguchi H, Ohba S, Chung UI, Choi JY
    • Journal Title

      Gene 416

      Pages: 53-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis2008

    • Author(s)
      Oshima Y, Akiyama T, Hikita A, Iwasawa M, Nagase Y, Nakamura M, Wakeyama H, Kawamura N, Ikeda T, Chung UI, Hennighausen L, Kawaguchi H, Nakamura K, Tanaka S
    • Journal Title

      J Biol Chem 283

      Pages: 26499-26508

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Regulation of osteoarthritis development by Wnt-Vcatenin signaling through the endochondral ossification process.2008

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Res 24

      Pages: 8-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcriptional activator2008

    • Author(s)
      Tamiya H, Ikeda T, Jung JH, Saito T, Jung YK, Kawaguchi H, Ohba S, Chung UI, Choi JY
    • Journal Title

      Gene 416

      Pages: 53-60

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Clin Invest 118

      Pages: 2506-2515

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI
    • Journal Title

      Dev Cell 14

      Pages: 689-699

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Clin Invest 118

      Pages: 2506-2515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders.2008

    • Author(s)
      Yamakawa K, Kamekura S, Kawamura N, Saegusa M, Kamei D, Murakami M, Kudo I, Uematsu S, Akira S, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Arthritis Rheum 58

      Pages: 172-183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Effect of 2-methacryloyloxyethyl phosphorylcholine concentration on photo-induced graft polymerization of polyethylene in reducing the wear of orthopaedic bearing surface2008

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Hashimoto M, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Journal Title

      J Biomed Mater Res A 86

      Pages: 439-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Patchedl haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI.
    • Journal Title

      Dev Cell. 14(5)

      Pages: 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly (MPC) graft chains induced by gamma-ray irradiation2008

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Konno T, Hashimoto M, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Journal Title

      J Biomed Mater Res B 84

      Pages: 320-327

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders2008

    • Author(s)
      Yamakawa K, Kamekura S, Kawamura N, Saegusa M, Kamei D, Murakami M, Kudo I, Uematsu S, Akira S, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Arthritis Rheum 58

      Pages: 172-183

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] The Distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease.2008

    • Author(s)
      Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S
    • Journal Title

      Arthritis Rheum 58

      Pages: 2764-2775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Endochondral ossification signals in cartilage degradation during osteoarthritis progression in experimental mouse models.2008

    • Author(s)
      Kawaguchi H
    • Journal Title

      Mol Cells 25

      Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Biol Chem. 283(36)

      Pages: 24682-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Endochondral ossification signals in cartilage degradation during osteoarthritis progression in experimental mouse models2008

    • Author(s)
      Kawaguchi H
    • Journal Title

      Mol Cells

      Volume: 25 Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.2008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem 283

      Pages: 24682-24689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Journal Article] Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes2007

    • Author(s)
      Liu G, Kawaguchi H, Ogasawara T, Asawa Y, Kishimoto J, Takahashi T, Chung UI, Yamaoka H, Asato H, Nakamura K, Takato T, Hoshi K
    • Journal Title

      J Biol Chem 282(28)

      Pages: 20407-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation2007

    • Author(s)
      Ogata N, Kawaguchi H, Chung UI, Roth SI, Segre GV
    • Journal Title

      J Biol Chem 2007 282(49)

      Pages: 35757-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] S100A1 and B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      EMBO Rep 8

      Pages: 504-509

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] A novel osteogenic helioxanthin-derivative acts in a BMP-dependent manner2007

    • Author(s)
      Ohba S, Nakajima K, Komiyama Y, Kugimiya F, Igawa K, Itaka K, Moro T, Nakamura K, Kawaguchi H, Takato T, Chung UI
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 854-860

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] 脂質代謝関連分子による骨代謝調節2007

    • Author(s)
      篠田 裕介, 川口 浩
    • Journal Title

      骨粗鬆症治療 Vol. 6. no. 2

    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes2007

    • Author(s)
      Liu G, Kawaguchi H, Ogasawara T, Asawa Y, Kishimoto JI, Takahashi T, Chung UI, Yamaoka H, Asato H, Nakamura K, Takato T, Hoshi K
    • Journal Title

      J Biol Chem 282

      Pages: 20407-20415

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Erk pathways negatively regulate matrix mineralization2007

    • Author(s)
      Kono SJ, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K, Kawaguchi H, Tanaka S
    • Journal Title

      Bone 40(1)

      Pages: 68-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe T, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 on bone repair : a dose-escalation prosective trial on patients with osteotomy.2007

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation2007

    • Author(s)
      Ogata N, Kawaguchi H, Chung UI, Roth SI, Segre GV.
    • Journal Title

      J Biol Chem 282

      Pages: 35757-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 on bone repair:a dose-escalation prospective trial on patients with osteotomy2007

    • Author(s)
      Hiroshi Kawaguchi, et. al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] GSK-3beta controls osteogenesis through regulating Runx2 activity2007

    • Author(s)
      Kugimiya F, Kawaguchi H, Ohba S, Pawamura N, Hirata M, Chikuda H, Azuma Y, Woodgett. JR, Nakamura K, Chung UI.
    • Journal Title

      PLoS ONE 2(9)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390410
  • [Journal Article] Diet and lifestyle associated with increased bone mineral density : cross-sectional study of Japanese elderly women at an osteoporosis outpatient clinic2007

    • Author(s)
      Muraki S, Yamamoto S, Ishibashi H, Oka H, Yoshimura N, Kawaguchi H, Nakamura K
    • Journal Title

      J Orthop Sci 12

      Pages: 317-320

    • NAID

      10019816110

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 On bone rePair:a dose-escalatlon prospective trial on patients with osteotomy2007

    • Author(s)
      Hiroshi Kawaguchi, et. al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      EMBO Rep. 8(5)

      Pages: 504-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 on bone repair : a dose-escalation prospective trial on patients with osteotomy.2007

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation2007

    • Author(s)
      Ogata N, Kawaguchi H, Chung UI, Roth SI, Segre GV.
    • Journal Title

      J Biol Chem. 282(49)

      Pages: 35757-64

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Local application of recombinant human fibrobalst growth factor-2 on bone repair: a dose-escalation prospective trial on patients with osteotomy2007

    • Author(s)
      Hiroshi Kawaguchi, et. al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 2(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] GSK-3β controls osteogenesis through regulating Runx2 activity2007

    • Author(s)
      Kugimiya F, Kawaguchi H, Ohba S, Kawamura N, Hirata M, Chikuda H, Azuma Y, Woodgett JR, Nakamura K, Chung UI
    • Journal Title

      PLoS ONE 2

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Tobe T, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE 2(10)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS ONE 2(10)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390410
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI.
    • Journal Title

      FASEB J. 21(8)

      Pages: 1777-87

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Continuous activation of Gαq in osteoblasts results in osteopenia through impaired osteoblast differentiation2007

    • Author(s)
      Ogata N, Kawaguchi H, Chung UI, Roth SI, Segre GV
    • Journal Title

      J Biol Chem 282

      Pages: 35757-64

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-390

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 on bone repair : a dose-escalation prospective trial on patients with osteotomy.2007

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Identification and characterization of the human SOX_6 promoter2007

    • Author(s)
      Ikeda T, Chung U, Kawaguchi H (その他7名)
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-90

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Prevention of cartilage destruction with intraarticular osteoclastogenesis inhibitory factor/osteoprotegerin in a murine model of osteoarthritis2007

    • Author(s)
      Shimizu S, Asou Y, Itoh S, Cung UI, Kawaguchi H, Shinomiya K, Muneta T
    • Journal Title

      Arthritis Rheum 56

      Pages: 3358-3365

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      FASEB J 21

      Pages: 1777-1787

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Aktl in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 2(10)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Growth Factorsと骨芽細胞2007

    • Author(s)
      川口 浩
    • Journal Title

      医学のあゆみ 221・1

    • Data Source
      KAKENHI-PROJECT-17390410
  • [Journal Article] Local application of recombinant human fibroblast growth factor-2 on bone repair : a dose-escalation prospective trial on patients with osteotomy.2007

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      J Orthop Res 25

      Pages: 480-487

    • Data Source
      KAKENHI-PROJECT-18659436
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      Rev Endocr Metab Disord 7

      Pages: 17-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches2006

    • Author(s)
      Kawaguchi H
    • Journal Title

      Rev Endocr Metab disord 7

      Pages: 17-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Decreased activities of daily living and associations with bone loss among aged residents in a rural Japanese community : the Miyama Study2006

    • Author(s)
      Oka H, Yoshimura N, Kinoshita H, Saiga A, Kawaguchi H, Nakamura K
    • Journal Title

      J Bone Miner Metab 24

      Pages: 307-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Cumulative incidence and changes in prevalence of vertebral fractures in a rural Japanese community : A 10-year follow-up of the Miyama cohort2006

    • Author(s)
      Yoshimura N, Kinoshita H, Oka H, Muraki S, Mabuchi A, Kawaguchi H, Nakamura K
    • Journal Title

      Arch Osteoporosis DOI10.1007/s11657-006-0007-0(online publication)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] A large-scale genetic association study of ossification of the posterior longitudinal ligament of the spine2006

    • Author(s)
      Horikoshi T, Maeda K, Kawaguchi Y, Chiba K, Mori K, Koshizuka Y, Hirabayashi S, Sugimori K, Matsumoto M, Kawaguchi H, Takahashi M, Inoue H, Kimura T, Matsusue Y, Inoue I, Baba H, Nakamura K, Ikegawa S
    • Journal Title

      Hum Genet 119

      Pages: 611-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Vertebral hemangioma compressing the thoracic spinal cord : application of computer-aided navigation and intraoperative spinal sonography for surgery through anterior and posterior approaches2006

    • Author(s)
      Sakanishi H, Hoshi K, Nakajima S, Akune T, Takeshita K, Yamamoto M, Kawaguchi H, Nakamura K, Seichi A
    • Journal Title

      J Orthop Sci 11

      Pages: 294-7

    • NAID

      10018151337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Tailor-made tricalcium phosphate bone implant directly fabricated by a three-dimensional ink-jet printer2006

    • Author(s)
      Igawa K, Mochizuki M, Sugimori O, Shimizu K, Yamazawa Y, Kawaguchi H, Nakamura K, Takato T, Nishimura R, Suzuki S, Anzai M, Chung UI, Sasaki N
    • Journal Title

      J Artif Organs 9

      Pages: 234-40

    • NAID

      10025704200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] 骨・軟骨再生促進因子2006

    • Author(s)
      川口浩
    • Journal Title

      分子リウマチ 3-2

      Pages: 107-115

    • Data Source
      KAKENHI-PROJECT-18659436
  • [Journal Article] The Frank Stinchfield Award Grafting of biocompatible MPC polymer on cross-linked polyethylene liner surface for extending longevity of artificial hip joints2006

    • Author(s)
      Moro T, Takatori Y, Ishihara K, Nakamura K, Kawaguchi H
    • Journal Title

      Clinical Orthopaedics (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] Neurological level diagnosis of cervical stenotic myelopathy2006

    • Author(s)
      Seichi A, Takeshita K, Kawaguchi H, Matsudaira K, Higashikawa A, Ogata N, Nakamura K
    • Journal Title

      Spine 31

      Pages: 1338-43

    • NAID

      10020593362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Runx2 contributes to pathogenesis of osteoarthritis in mice after induction of knee joint instability2006

    • Author(s)
      Kamekura S, Kawasaki Y, Hoshi K, Shimoaka T, Chikuda H, Maruyama Z, Komori T, Sato S, Takeda S, Karsenty G, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 54

      Pages: 2462-2470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Carminerin contributes to chondrocyte calcification during endochondral ossification2006

    • Author(s)
      Yamada T, Kawano H, Koshizuka Y, Fukuda T, Yoshimura K, Kamekura S, Saito T, Ikeda T, Kawasaki Y, Azuma Y, Ikegawa S, Hoshi K, Chung UI, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Nat Med. 12(6)

      Pages: 665-70

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Risk factors for knee osteoarthritis in Japanese men : a case-control study2006

    • Author(s)
      Yoshimura N, Kinoshita H, Hori N, Nishioka T, Ryujin M, Mantani Y, Miyake M, Takeshita T, Ichinose M, Yoshida M, Oka H, Kawaguchi H, Nakamura K, Cooper C
    • Journal Title

      Mod Rheumatol 16

      Pages: 24-9

    • NAID

      10017351821

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Runx2 contributes to pathogenesis of osteoarthritis in mice after induction of knee joint instability2006

    • Author(s)
      Kamekura S, Kawasaki Y, Hoshi K, Shimoaka T, Chikuda H, Maruyama Z, Komori T, Sato S, Takeda S, Karsenty G, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 54

      Pages: 2462-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Masuda H, Chikuda H, Suga T, Kawaguchi H, Kuro-o M : Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice2006

    • Author(s)
      Masuda H, Chikuda H, Suga T, Kawaguchi H, Kuro-o M
    • Journal Title

      Rev Endocr Metab disord 7

      Pages: 17-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] 骨・軟骨再生促進因子2006

    • Author(s)
      川口浩
    • Journal Title

      分子リウマチ 3-2

      Pages: 107-115

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      J Cell Biochem 99

      Pages: 196-208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Regulation of Bone Formation by Adiponectin Through Autocrine/Paracrine and Endocrine Pathways.2006

    • Author(s)
      Yusuke Shinoda, Masayuki Yamaguchi, Naoshi Ogata, Toru Akune, Naoto Kubota, Toshimasa Yamauchi, Yasuo Terauchi, Takashi Kadowaki, Yasuhiro Takeuchi, Seiji Fukumoto, Toshiyuki Ikeda, Kazuto Hoshi, Ung-il Chung, Kozo Nakamura, Hiroshi Kawaguchi
    • Journal Title

      Journal of Cellular Biochemistry 99

      Pages: 196-196

    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      J Cell Biochem 99

      Pages: 196-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Suppression of adjuvant-induced arthritic bone destruction by cyclooxygenase-2 selective agents with and without inhibitory potency against carbonic anhydrase II2006

    • Author(s)
      14. Katagiri M, Ogasawara T, Hoshi K, Chikazu D, Kimoto A, Noguchi M, Sasamata M, Harada S, Akama H, Tazaki H, Chung UI, Takato T, Nakamura K, Kawaguchi H
    • Journal Title

      J Bone Miner Res 21

      Pages: 219-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Melecular backgrounds of age-related osteoporosis from mouse genetics approaches2006

    • Author(s)
      Kawaguchi Hiroshi
    • Journal Title

      Reviews in endocrine & metabolic disorders 7・1-2

      Pages: 17-22

    • Data Source
      KAKENHI-PROJECT-17390410
  • [Journal Article] Carminerin contributes to chondrocyte calcification during endochondral ossification2006

    • Author(s)
      Yamada T, Kawano H, Koshizuka Y, Fukuda T, Yoshimura K, Kamekura S, Saito T, Ikeda T, Kawasaki Y, Azuma Y, Ikegawa S, Hoshi K, Chung UI, Nakamura K, Kato S, Kawaguchi H
    • Journal Title

      Nature Med 12

      Pages: 665-670

    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H.
    • Journal Title

      J Cell Biochem 99(1)

      Pages: 196-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Kawaguchi H
    • Journal Title

      Rev Endocr Metab Disord 7

      Pages: 17-22

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Physiological role of bone morphogenetic proteins in osteogenesis2006

    • Author(s)
      Kugimiya F, Ohba S, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      J Bone Miner Metab 24

      Pages: 95-9

    • NAID

      10018194131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Distinct association of gene polymorphisms of estrogen receptor and vitamin D receptor with lumbar spondylosis in postmenopausal women2006

    • Author(s)
      Koshizuka Y, Ogata N, Shiraki M, Hosoi T, Seichi A, Takeshita K, Nakamura K, Kawaguchi H
    • Journal Title

      Eur Spine J 15

      Pages: 1521-1528

    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials2006

    • Author(s)
      Yamaoka H, Asato H, Ogasawara T, Nishizawa S, Takahashi T, Nakatsuka T, Koshima I, Nakamura K, Kawaguchi H, Chung UI, Takato T, Hoshi K
    • Journal Title

      J Biomed Mater Res A 78

      Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      Rev Endocr Metab Disord 7

      Pages: 17-22

    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      Rev Rheumatol 7

      Pages: 17-22

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      Rev Endocr Metab Disord 7

      Pages: 17-22

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability2006

    • Author(s)
      Kamekura S, Kawasaki Y, Hoshi K, Shimoaka T, Chikuda H, Maruyama Z, Komori T, Sato S, Takeda S, Karsenty G, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum. 54(8)

      Pages: 2462-70

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Molecular backgrounds of age-related osteoporosis from mouse genetics approaches.2006

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      Rev Endocr Metab Disord 7

      Pages: 17-22

    • Data Source
      KAKENHI-PROJECT-18659436
  • [Journal Article] インスリン受容体基質(IRS)シグナルによる骨形成調節と骨再生医療への応用.2005

    • Author(s)
      川口浩
    • Journal Title

      日本整形外科学会雑誌 79

      Pages: 946-953

    • NAID

      10017472088

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] 再生医療:再生促進因子2005

    • Author(s)
      川口 浩
    • Journal Title

      日本臨床 63

      Pages: 676-679

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Suppression of aging in mice by the hormone Klotho2005

    • Author(s)
      Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gumani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M
    • Journal Title

      Mech Ageing Dev 126

      Pages: 1274-1283

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] 関節のナノ表面処理による人工股関節の弛みの阻止2005

    • Author(s)
      茂呂徹, 高取吉雄, 中村耕三, 川口浩
    • Journal Title

      整形外科 56(2)

      Pages: 170-170

    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes2005

    • Author(s)
      Kawaguchi, H., et al.
    • Journal Title

      Genes Dev. 18・19

      Pages: 2418-2429

    • Data Source
      KAKENHI-PROJECT-14207075
  • [Journal Article] 骨・軟骨の再生医療.2005

    • Author(s)
      緒方直史, 川口浩
    • Journal Title

      「老年医学update 2005-2006」(編集:日本老年医学会雑誌編集委員会)

      Pages: 199-206

    • NAID

      50000092845

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] 性ホルモンと骨粗鬆症2005

    • Author(s)
      河野博隆, 川口浩
    • Journal Title

      リウマチ科 33(6)

      Pages: 654-661

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] Klotho insufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells2005

    • Author(s)
      Anamizu Y, Kawaguchi H, Seichi A, Yamaguchi S, Kawakami E, Kanda N, Matsubara S, Kuro-o M, Nabeshima Y, Nakamura K, Oyanagi K
    • Journal Title

      Acta Neuropathol 109

      Pages: 457-466

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] 再生医療:再生促進因子.2005

    • Author(s)
      川口浩
    • Journal Title

      日本臨床(増刊号1:関節リウマチ-成因研究から治療の新時代へ) 63

      Pages: 676-679

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005

    • Author(s)
      Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung U.
    • Journal Title

      Biochem Biophys Res Commun 333(4)

      Pages: 1300-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] インスリン受容体基質(IRS)シグナルによる骨形成調節と骨再生医療への応用.2005

    • Author(s)
      川口浩ほか
    • Journal Title

      日本整形外科学会雑誌 79

      Pages: 946-953

    • NAID

      10017472088

    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] 変形性関節症の病態・治療への分子生物学的アプローチ.2005

    • Author(s)
      川口浩
    • Journal Title

      Pharma Medica(増刊号) 23

      Pages: 35-39

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] 変形性関節症の病態・治療への分子生物学的アプローチ.2005

    • Author(s)
      川口浩
    • Journal Title

      Pharma Medica(増刊号) 23(Suppl.)

      Pages: 35-39

    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Osteoarthritis development in novel experimental mouse models induced by knee joint instability2005

    • Author(s)
      Kamekura S, Hoshi K, Shimoaka T, Chung UI, Chikuda H, Yamada T, Uchida M, Ogata N, Seichi A, Nakamura K, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 13

      Pages: 632-641

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Distinct roles of Sox5,Sox6,and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Chung U
    • Journal Title

      J Bone Miner Metab 338

      Pages: 872-879

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Regenerative Therapy of Bone / Cartilage2005

    • Author(s)
      Oba Shinsuke, Igawa Kazuyo, Nakamura Kozo, Kawaguchi Hiroshi, Takatou Takeshi, Chung, Ung-il
    • Journal Title

      Geriatrics Update 2005-2006 (Edited by Japan Geriatrics Society Journal Editing Committee) (Medicalview company)

      Pages: 199-206

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Insulin receptor substrate-1 is required for bone anabolic function of parathyroid hormone in mice2005

    • Author(s)
      Yamaguchi M, Ogata N, Shinoda Y, Akune T, Kamekura S, Terauchi Y, Kadowaki T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Endocrinology 146

      Pages: 2620-2628

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Journal Article] Involvement of endogenous bone morphogenetic protein (BMP)2 and BMP6 in bone formation.2005

    • Author(s)
      Kugimiya F, Kawaguchi H, Kamekura S, Chikuda H, Ohba S, Yano F, Ogata N, Katagiri T, Harada Y, Azuma Y, Nakamura K, Chung U.
    • Journal Title

      J Biol Chem 280

      Pages: 35704-35712

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Nakamura K, Ikegawa S, Chung U.
    • Journal Title

      J Bone Miner Metab 23

      Pages: 337-340

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Osteoarthritis development in novel exper imental mouse models induced by knee joint instability.2005

    • Author(s)
      Kamekura S, Hoshi K, Shimoaka T, Chung U, Chikuda H, Yamada T, Uchida M, Ogata N, Seichi A, Nakamura K, Kawaguchi H.
    • Journal Title

      Osteoarthritis Cartilage 13(7)

      Pages: 632-641

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells2005

    • Author(s)
      Kawaguchi H
    • Journal Title

      J Bone Miner Metab 23(4)

      Pages: 275-279

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390530
  • [Journal Article] Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells.2005

    • Author(s)
      Hiroshi Kawaguchi
    • Journal Title

      Journal of Bone and Mineral Metabolism 23(4)

      Pages: 275-279

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390530
  • [Journal Article] Mechanism of osteogenic induction by FK506 via BMP/Smad pathways.2005

    • Author(s)
      Kugimiya F, Yano F, Ohba S, Igawa K, Nakamura K, Kawaguchi H, Chung U.
    • Journal Title

      Biochem Biophys Res Commun 338

      Pages: 872-879

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 新素材による人工股関節の開発2005

    • Author(s)
      茂呂徹, 高取吉雄, 中村耕三, 川口浩, 石原一彦
    • Journal Title

      整形・災害外科 48(3)

      Pages: 245-250

    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] ポリエチレンライナー表面のMPC処理は人工股関節の弛みを抑制する-ナノ表面制御による長寿命型人工股関節の開発2005

    • Author(s)
      茂呂徹, 高取吉雄, 中村耕三, 川口浩, 石原一彦
    • Journal Title

      Hip Joint 31

      Pages: 469-474

    • NAID

      10016834060

    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] 閉経後の骨粗鬆症の治療:治療薬の種類と作用機序2005

    • Author(s)
      篠田裕介, 川口浩
    • Journal Title

      Mebio 22(11)

      Pages: 92-97

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] 骨・軟骨の再生医療2005

    • Author(s)
      鄭 雄一, 川口 浩, 中村 耕三ら
    • Journal Title

      分子細胞治療 4巻・4号

      Pages: 47-47

    • NAID

      50000092845

    • Data Source
      KAKENHI-PROJECT-17659461
  • [Journal Article] PPARg insufficiency enhances osteogenesis from bone marrow progenitors.2004

    • Author(s)
      Akune T, Oba S, Kamekura S, Yamaguchi M, Chung U, Kubota N, Terauchi Y, Harada Y, Azuma Y, Kadowaki T, Nakamura K, Kawaguchi H.
    • Journal Title

      J Clin Invest 113

      Pages: 846-855

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kawano H, Sekine K, Matsumoto T, Fukuda T, Azuma Y, Chung U, Chambon P, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct Role of Smad Pathways and p38 Pathways in Cartilage-specific Gene Expression in Synovial Fibroblasts.2004

    • Author(s)
      Seto H, Kamekura S, Miura T, Yamamoto A, Chikuda H, Ogata T, Hiraoka H, Nakamura K, Kurosawa H, Chung U, Kawaguchi H, Tanaka S.
    • Journal Title

      J Clin Invest 113

      Pages: 718-726

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct osteogenic mechanisms of bones of distinct origins.2004

    • Author(s)
      Chung U, Kawaguchi H, Takato T, Nakamura K.
    • Journal Title

      J Orthop Sci 9

      Pages: 410-414

    • NAID

      80016822765

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Mabuchi A, Kou I, Seki S, Takato T, Nakamura K, Kawaguchi H, Ikegawa S, Chung U.
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 移植による骨軟骨再生2004

    • Author(s)
      川口 浩
    • Journal Title

      治療学 38(10)

      Pages: 1120-1127

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] RA関節破壊治療のためのターゲット分子2004

    • Author(s)
      川口浩
    • Journal Title

      Pharma Medica 22(3)

      Pages: 115-120

    • Data Source
      KAKENHI-PROJECT-14370452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9(the SOX trio)provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Kawaguchi H, Ikegawa S, Chung U
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 移植による骨軟骨再生2004

    • Author(s)
      川口 浩
    • Journal Title

      治療学 38(10)

      Pages: 1120-1127

    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis2004

    • Author(s)
      Moro T, Takatori Y, Ishihara K, Konno T, Takigawa Y, Matsushita T, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Nature Materials 3(11)

      Pages: 829-836

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis.2004

    • Author(s)
      Moro T, Takatori Y, Ishihara K, Konno T, Takigawa Y, Matsushita T, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Nature Mater 3(11)

      Pages: 829-836

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] 再生医療:再生促進因子2004

    • Author(s)
      川口 浩
    • Journal Title

      日本臨床 63(増刊1)

      Pages: 676-679

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] RA関節破壊とCOX-2阻害剤2004

    • Author(s)
      川口浩
    • Journal Title

      整形災害外科 47(9)

      Pages: 1039-1045

    • Data Source
      KAKENHI-PROJECT-14370452
  • [Journal Article] 加齢に伴う骨粗鬆化の分子メカニズム2004

    • Author(s)
      川口 浩
    • Journal Title

      日本老年医学会雑誌 41(6)

      Pages: 612-615

    • NAID

      10014285579

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] BMPと骨形成2004

    • Author(s)
      釘宮典孝, 鄭 雄一, 川口 浩
    • Journal Title

      クリニカル・カルシウム 14

      Pages: 173-179

    • Data Source
      KAKENHI-PROJECT-16659400
  • [Journal Article] 原発性骨粗鬆症に関する最近の知見2004

    • Author(s)
      川口 浩
    • Journal Title

      Medical Practice 21(10)

      Pages: 1665-1669

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] 加齢に伴う骨粗鬆化の分子メカニズム2004

    • Author(s)
      川口 浩
    • Journal Title

      日本老年医学会雑誌 41(6)

      Pages: 612-615

    • NAID

      10014285579

    • Data Source
      KAKENHI-PROJECT-12137201
  • [Journal Article] Stimulatory G protein (Gs) directly regulates hypertrophic differentiation of growth plate cartilage in vivo.2004

    • Author(s)
      Bastepe M, Weinstein LS, Ogata N, Kawaguchi H, Juppner H, Kronenberg HM, Chung U.
    • Journal Title

      Proc Nat Acad Sci USA 101

      Pages: 14794-14799

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] ヒトklotho遺伝子多型2004

    • Author(s)
      川野健一, 川口浩
    • Journal Title

      日本臨床 62(増刊号2)

      Pages: 190-194

    • Data Source
      KAKENHI-PROJECT-12137201
  • [Journal Article] 骨・軟骨分化決定因子の解析から再生医学へ2004

    • Author(s)
      鄭 雄一, 池田敏之, 川口 浩, 中村耕三, 高戸 毅
    • Journal Title

      分子リウマチ 2

      Pages: 22-26

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] COX-2阻害薬による骨破壊抑制の可能性2004

    • Author(s)
      川口浩
    • Journal Title

      Pharma Medica 22(12)

      Pages: 39-44

    • Data Source
      KAKENHI-PROJECT-14370452
  • [Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.2004

    • Author(s)
      Chikuda H, Kugimiya F, Ikeda T, Ogasawara T, Shimoaka T, Kawano H, Kamekura S, Tsuchida A, Yokoi N, Nakamura K, Komeda K, Chung U, Kawaguchi H.
    • Journal Title

      Genes Dev 18

      Pages: 2418-2429

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 骨折治癒と成長因子・サイトカインシグナル2004

    • Author(s)
      川口 浩
    • Journal Title

      The Bone 18(6)

      Pages: 731-739

    • Data Source
      KAKENHI-PROJECT-15390451
  • [Journal Article] SRC-1 is necessary for skeletal responses to sex hormones in both males and females.2004

    • Author(s)
      Yamada T, Kawano H, Sekine K, Matsumoto T, Fukuda T, Azuma Y, Chung U, Chambon P, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      J Bone Miner Res 19

      Pages: 1452-1461

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 運動器の再生医療2003

    • Author(s)
      川口 浩, 他
    • Journal Title

      THE BONE 17

      Pages: 73-88

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370454
  • [Journal Article] 骨粗鬆症の病型と病態2003

    • Author(s)
      川口 浩
    • Journal Title

      Pharma Medica 21

      Pages: 10-13

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370454
  • [Journal Article] Pathology of osteoporosis.2003

    • Author(s)
      Kawaguchi H
    • Journal Title

      Pharma Medica 21

      Pages: 10-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370454
  • [Journal Article] Regeneration medicine of motor organ2003

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      THE BONE 17

      Pages: 73-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370454
  • [Journal Article] Surface and wear-resistant properties of MPC polymer grafted cross-linked polyethylene

    • Author(s)
      Kyomoto M, Moro T, Ishihara K, Konno T, Takadama T, Yamawaki N, Takatori Y, Nakamura K, Kawaguchi H
    • Journal Title

      Biomaterials (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] The Frank Stichfield Award Grafting of biocompatible MPC polymer on cross-linked polyethylene liner surface for extending longevity of artificial hip joints.

    • Author(s)
      Moro T, Takatori Y, Ishihara K, Nakamura K, Kawaguchi H
    • Journal Title

      Clin Orthop (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] The mid-term efficacy of intra-articular hyaluronic acid injections on joint structure: a nested case control study.

    • Author(s)
      Oka H, Akune T, Muraki S, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N:
    • Journal Title

      Mod Rheumatol (in press).

    • NAID

      10031189167

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Title : Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system

    • Author(s)
      Hojo H, Yano F, Ohba S, Igawa K, Nakajima K, Komiyama Y, Kan A, Ikeda T, Yonezawa T, Woo JT, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      J Bone Miner Metab (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Reverse and forward genetic approaches to the pathophysiology of osteoporosis.

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      Geriatrics & Gerontology International (in press)

    • NAID

      10018027199

    • Data Source
      KAKENHI-PROJECT-12137201
  • [Journal Article] Health-related quality of life with vertebral fracture, lumbar spondylosis and knee osteoarthritis in Japanese men : the ROAD study

    • Author(s)
      Muraki S, Akune T, Oka H, En-yo Y, Saika A, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
    • Journal Title

      Arch Osteoporos (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Distinct effects of PPARγ insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells.

    • Author(s)
      Kawaguchi H, et al.
    • Journal Title

      Journal of Bone and Joint Metabolism (in press)

    • Data Source
      KAKENHI-PROJECT-12137201
  • [Journal Article] Grafting of biocompatible polymer for longevity of artificial hip joints

    • Author(s)
      Moro T, Takatori Y, Ishihara K, Nakamura K and Kawaguchi H
    • Journal Title

      Clin Orthop Rel Res 453

      Pages: 58-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.
    • Journal Title

      Nat Med (in press)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Surface and wear-resistant properties of MPC polymer grafted cross-linked polyethylene

    • Author(s)
      Kyomoto M, Mro T, Ishihara K, Konno T, Takadama T, Yamawaki N, Takatori Y, Nakamura K, Kawaguchi H
    • Journal Title

      Biomaterials (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Journal Article] β-catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region.

    • Author(s)
      Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum-US

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] GSK-3beta controls osteogenesis through regulating Runx2 activity

    • Author(s)
      Kugimiya F, Kawaguchi H, Ohba S, Kawamura N, Hirata M, Chikuda H, Azuma Y, Woodgett JR, Nakamura K, Chung UI.
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Contribution of Metabolic Conditions to Ossification of the Posterior Longitudinal Ligament of the Spine.

    • Author(s)
      Hiroshi Kawaguchi, et al.
    • Journal Title

      OPLL-Ossification of the Posterior Longitudinal Ligament 2nd Edition (edited by K.Yonenobu, T.Nakamura, Y.Toyama) (Springer-Verlag) (Tokyo) 7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Journal Article] Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: A 3-year follow-up of the ROAD study.

    • Author(s)
      Yoshimura N, Muraki S, Oka H, TanakaS, Kawaguchi H, Nakamura K, and Akune T
    • Journal Title

      Osteoarthr Cartilage (in press)

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Risk factors for falls in a longitudinal population-based cohort study of Japanese men and women

    • Author(s)
      Muraki S, Akune T, Ishimoto Y, Nagata K, Yoshida M, Tanaka S, Oka H, Kawaguchi H, Nakamura K, and Yoshimura N
    • Journal Title

      The ROAD Study. Bone (in press)

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.

    • Author(s)
      Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H,Takato T, Kawaguchi H, and Chung UI
    • Journal Title

      Ann Rheum Dis(in press).

    • Data Source
      KAKENHI-PROJECT-22249056
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF2A during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Journal Title

      Nature Med (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Cohort profile : Research on Osteoarthritis/Osteoporosis Against Disability study

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
    • Journal Title

      Int J Epidemiol (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 膝関節診断支援方法及び装置並びにプログラム2012

    • Inventor(s)
      岡敬之、吉村典子、川口浩、中村耕三
    • Industrial Property Rights Holder
      岡敬之、吉村典子、川口浩、中村耕三
    • Acquisition Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 脊椎疾患診断支援装置、及び脊椎疾患診断支援プログラム2010

    • Inventor(s)
      岡敬之、吉村典子、阿久根徹、川口浩、中村耕三
    • Industrial Property Rights Holder
      岡敬之、吉村典子、阿久根徹、川口浩、中村耕三
    • Filing Date
      2010-04-19
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 膝関節診断支援方法及び装置並びにプログラム公開番号:2009

    • Inventor(s)
      岡敬之、川口浩、中村耕三
    • Industrial Property Rights Holder
      岡敬之、川口浩、中村耕三
    • Patent Publication Number
      2008-093229
    • Filing Date
      2009-06-10
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 膝関節診断支援方法及び装置並びにプログラム2009

    • Inventor(s)
      岡敬之、川口浩、中村耕三
    • Industrial Property Rights Holder
      岡敬之、川口浩、中村耕三
    • Patent Publication Number
      2008-093229
    • Filing Date
      2009-06-10
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 膝関節診断支援方法及び装置並びにプログラム2008

    • Inventor(s)
      岡敬之、吉村典子、川口浩、中村耕三
    • Industrial Property Rights Holder
      岡敬之、吉村典子、川口浩、中村耕三
    • Filing Date
      2008-04-24
    • Acquisition Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Industrial Property Rights Holder
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Filing Date
      2006-12-15
    • Data Source
      KAKENHI-PROJECT-18659436
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本 政之, 茂呂 徹, 石原 一彦, 金野 智浩, 中村 耕三, 高取 吉雄, 川口 浩, 高玉 博朗, 近藤 誠, 山脇 昇
    • Industrial Property Rights Holder
      日本メディカルマテリアル株式会社, 茂呂 徹, 石原 一彦, 中村 耕三, 高取 吉雄, 川口 浩
    • Industrial Property Number
      2006-028529
    • Filing Date
      2006-02-06
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Industrial Property Rights Holder
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Filing Date
      2006-12-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Patent] 低摩耗性摺動部材及びそれぞれを用いた人工関節2006

    • Inventor(s)
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Industrial Property Rights Holder
      同左
    • Filing Date
      2006-12-15
    • Data Source
      KAKENHI-PROJECT-15209049
  • [Patent] 組織癒着・関節拘縮防止材2006

    • Inventor(s)
      中村耕三, 石原一彦, 木村美都奈, 川口浩, 茂呂徹
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2006-08-24
    • Data Source
      KAKENHI-PROJECT-17591548
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Industrial Property Rights Holder
      同左
    • Filing Date
      2006-12-15
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Industrial Property Rights Holder
      京本政之, 二塚健, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 茂呂徹, 橋本雅美
    • Filing Date
      2006-12-15
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Patent] 組織癒着・関節拘縮防止材2006

    • Inventor(s)
      中村耕三, 石原一彦, 木村美都奈, 川口浩, 茂呂徹
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2006-08-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591548
  • [Patent] 低摩耗性摺動部材及びそれを用いた人工関節2006

    • Inventor(s)
      京本政之, 茂呂徹, 石原一彦, 金野智浩, 中村耕三, 高取吉雄, 川口浩, 高玉博朗, 近藤誠, 山脇昇
    • Industrial Property Rights Holder
      日本メディカルマテリアル株式会社, 茂呂徹, 石原一彦, 中村耕三, 高取吉雄, 川口浩
    • Industrial Property Number
      2006-028529
    • Filing Date
      2006-02-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390449
  • [Patent] 骨再生システム2005

    • Inventor(s)
      鄭 雄一 高戸 毅 大庭 伸介 中村 耕三 川口 浩
    • Filing Date
      2005-01-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390530
  • [Patent] 組織癒着・関節拘縮防止材2005

    • Inventor(s)
      中村耕三, 石原一彦, 木村美都奈, 川口浩, 茂呂徹
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2005-08-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591548
  • [Patent] 組織癒着・関節拘縮防止材2005

    • Inventor(s)
      中村 耕三, 石原 一彦, 木村 美都奈, 川口 浩, 茂呂 徹
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2005-08-25
    • Data Source
      KAKENHI-PROJECT-17591548
  • [Patent] 膝関節診断支援方法及び装置並びにプログラム

    • Inventor(s)
      中村耕三, 川口浩, 岡敬之
    • Industrial Property Rights Holder
      中村耕三, 川口浩, 岡敬之
    • Patent Publication Number
      2008-093229
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 関節軟骨の形成・維持におけるHIF-1αの機能解析2015

    • Author(s)
      岡田慶太、川口浩、他
    • Organizer
      第28回日本軟骨代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-06
    • Data Source
      KAKENHI-PROJECT-25670629
  • [Presentation] Gremlin1は過剰なメカニカルストレスで誘導され軟骨変性を促進する2015

    • Author(s)
      張成虎、川口浩、齋藤琢 他
    • Organizer
      第28回日本軟骨代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-06
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] 関節軟骨の形成・維持におけるHIF-1αの機能解析2015

    • Author(s)
      岡田慶太、川口浩、齋藤琢 他
    • Organizer
      第28回日本軟骨代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-06
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014

    • Author(s)
      Chang SH, Kawaguchi H, Saito T, et al.
    • Organizer
      Annual meeting of the American Society for bone and mineral research.
    • Place of Presentation
      Houston USA
    • Year and Date
      2014-09-15
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] HIF-1α REGULATES CONFIGURATION AND MAINTENANCE OF ARTICULAR CARTILAGE THROUGH INDUCTION OF ANABOLIC FACTORS AND SUPPRESSION OF CATABOLIC FACTORS2014

    • Author(s)
      Okada K, Kawaguchi H, et al.
    • Organizer
      Annual meeting of Osteoarthritis Research Society International.
    • Place of Presentation
      Paris
    • Year and Date
      2014-04-26
    • Data Source
      KAKENHI-PROJECT-25670629
  • [Presentation] HIF-1α IS ESSENTIAL FOR ARTICULAR CARTILAGE HOMEOSTASIS THROUGH INDUCTION OF ANABOLIC FACTORS AND SUPPRESSION OF CATABOLIC FACTORS.2014

    • Author(s)
      Okada K, Kawaguchi H, et al.
    • Organizer
      Annual meeting of the American Society for bone and mineral research.
    • Place of Presentation
      Houston
    • Year and Date
      2014-09-16
    • Data Source
      KAKENHI-PROJECT-25670629
  • [Presentation] 軟骨細胞におけるCCAAT/エンハンサー結合タンパク質ファミリーの発現と機能2014

    • Author(s)
      大隈知威、川口浩、齋藤琢 他
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] メタボリックシンドローム構成要因が変形性膝関節症の発症・進行に及ぼす影響 -The ROAD study 3年目の追跡.2012

    • Author(s)
      吉村典子、村木重之、岡敬之、中村耕三、川口浩、阿久根徹
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウィル愛知、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Endochondral ossification signal: A potential therapeutic target for osteoarthritis (Invited Lecture).2012

    • Author(s)
      Kawaguchi H
    • Organizer
      2012 ColdSpring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases.
    • Place of Presentation
      Suzhou, China
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] RBPjκ-dependent Notch signaling in chondrocytes modulates skeletal growth and osteoarthritis development2012

    • Author(s)
      Hosaka Y, Kawaguchi H, et al
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2012-06-11
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] 変形性膝関節症の発 生率およびその危険因子 - The ROAD study -.2012

    • Author(s)
      村木重之、阿久根徹、岡敬之、中村耕三、 川口浩、吉村典子
    • Organizer
      第85回日本整形外科学会学術 総会.
    • Place of Presentation
      国立京都国際会館、 京都
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] NF-/κBファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2012

    • Author(s)
      小林寛、川口浩, 他
    • Organizer
      日本軟骨代謝学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-03
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] NF-κB ファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2012

    • Author(s)
      小林寛、川口浩, 他
    • Organizer
      日本軟骨代謝学会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2012-03-09
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Notch/Rbpl/Hes1 signal in chondrocytes modulates osteoarthritis development.2012

    • Author(s)
      Sugita S, Hosaka Y, Kawaguchi H, et al.
    • Organizer
      World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] 高骨密度は動脈硬化および変形性腰椎症発症のリスクとなる:ROAD追跡調査より2012

    • Author(s)
      吉村典子、村木重之、岡敬之、田中栄、川口浩、阿久根徹
    • Organizer
      第30回日本骨代謝学会
    • Place of Presentation
      京王プラザホテル、東京
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] マウスモデルをベースにした変形性関節症の分子メカニズムの解明2012

    • Author(s)
      斎藤琢、川口浩
    • Organizer
      第30回日本骨代謝学会
    • Place of Presentation
      京王プラザホテル、東京
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] RBPjκ-dependent Notch signaling in chondrocytes modulates skeletal growth and osteoarthritis development.2012

    • Author(s)
      Hosaka Y, Kawaguchi H, et al
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Notch/Rbpl/Hes1 signal in chondrocytes modulates osteoarthritis development2012

    • Author(s)
      Sugita S, Hosaka Y, Kawaguchi H, et al
    • Organizer
      World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2012-04-26
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Notch/Rbpj/Hes1 シグナルによる軟骨内骨化および変形性関節症の制御2012

    • Author(s)
      杉田守礼、斎藤琢、保坂陽子、秋山治彦、鄭雄一、川口浩
    • Organizer
      第27回日本整形外科学会基礎学 術集会(最優秀演題賞受賞)
    • Place of Presentation
      名古屋国際会議場、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Transcriptional induction of ADAMTS5 by NF-κΒ family member RelA in chondrocytes during osteoarthritis development.2012

    • Author(s)
      Kobayashi H, Hirata M, Itoh S, Saito T, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases.
    • Place of Presentation
      Suzhou, China
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 要介護移行の予測 におけるロコチェックの有用性の検討 - The ROAD study -.2012

    • Author(s)
      吉村典子、村木重之、岡敬之、川口浩、 中村耕三、阿久根徹
    • Organizer
      第85回日本整形外科 学会学術総会.
    • Place of Presentation
      国立京都国際会館、京都
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Notch/Rbpj/Hes1 シグナルによる軟骨内 骨化および変形性関節症の制御(優秀演 題賞受賞).2012

    • Author(s)
      杉田守礼、斎藤琢、保坂陽子、深井厚、 秋山治彦、中村孝志、鄭雄一、川口浩
    • Organizer
      第30回日本骨代謝学会
    • Place of Presentation
      京王プラザホテル、東京
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 大規模コホートにおける変形性膝関 節症に関する生化学的マーカーの有用性.2012

    • Author(s)
      森田充浩、山田治基、吉村典子、伊達秀 樹、岡敬之、村木重之、阿久根徹、川口浩
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウィル愛知、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 変形性膝関節症および膝痛の危険因子 -The ROAD study.2012

    • Author(s)
      村木重之、阿久根徹、岡敬之、中村耕三、川口浩、吉村典子
    • Organizer
      第25回日本軟骨代謝学会.
    • Place of Presentation
      ウィル愛知、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Rbpj-dependent Notch signaling in chondrocytes modulates endochondral ossification during osteoarthritis development through transcriptional induction by Hes1.2012

    • Author(s)
      Sugita S, Hosaka Y, Kawaguchi H, et al.
    • Organizer
      American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Minneaplis, Minnesota, USA
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Rbpj-dependent Notch signaling in chondrocytes modulates endochondral ossification during osteoarthritis development through transcriptional induction by Hes12012

    • Author(s)
      Sugita S, Hosaka Y, Kawaguchi H, et al
    • Organizer
      American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Minneaplis, Minnesota, USA
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] ポリエチレン摺動面のMPCポリマー処理(シンポジウム:人工 関節成績改善に繋がる近未来の医療用素 材).2012

    • Author(s)
      高取吉雄、茂呂徹、京本政之、石原一彦、川口浩、中村耕三
    • Organizer
      第27回日本整形外科学会基礎学術 集会.
    • Place of Presentation
      名古屋国際会議 場、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Notch/Rbpl/Hes1 signal in chondrocytes modulates osteoarthritis development.2012

    • Author(s)
      Sugita S, Hosaka Y, Hikata T, Akiyama H, Long F, Chung UI, Saito T, Kawaguchi H:
    • Organizer
      2012 World Congress on Osteoarthritis (OARSI).
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] NF-κBファミ リー分子RelA/p65 は軟骨細胞においてADAMTS5を転写誘導して変形性関節症の 発症に関与する(シンポジウム:軟骨変性).2012

    • Author(s)
      小林寛、平田真、伊藤祥三、斎藤琢、鄭 雄一、中村耕三、川口浩
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウィル愛知、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Prevention and repair of cartilage degeneration by a novel thienoindazole-derivative compound.2012

    • Author(s)
      Yano F, Hosaka Y, Fukai A, Saito T, Hojo H, Ohba S, Kawaguchi H, Chung UI
    • Organizer
      2012 World Congress on Osteoarthritis (OARSI).
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Hes1, a transcriptional target of Notch signaling, modulates endochondral ossification during osteoarthritis development.2012

    • Author(s)
      Sugita S, Hosaka Y, Saito T, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases.
    • Place of Presentation
      Suzhou, China
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Notch/Rbpjシグナルは骨格形成と変形性関節症の進行において軟骨内骨化の後期分化過程を制御する(シンポジウム:軟骨変性).2012

    • Author(s)
      保坂陽子、斎藤琢、杉田守礼、深井厚、日方智宏、秋山治彦、中村孝志、中村耕三、鄭雄一、川口浩
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウィル愛知、愛知
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] コンピュータ自動計 測を用いた定量評価に基づく 3 年間での 膝X線画像縦断変化に関する研究 - TheROAD study -.2012

    • Author(s)
      岡敬之、村木重之、阿久根徹、中村耕三、 川口浩、吉村典子
    • Organizer
      第85回日本整形外科学会学術総会
    • Place of Presentation
      国立京都国際 会館、京都
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Endochondral ossification signal: A potential therapeutic target for osteoarthritis2012

    • Author(s)
      Kawaguchi H
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] GSK-3αとGSK-3βは協調的にRelA/NF-κB p65のリン酸化を介して軟骨細胞初期分化を制御する2011

    • Author(s)
      伊藤祥三、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] NF-κB ファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2011

    • Author(s)
      小林寛、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 変形性関節症up-to-date-その診断、治療、そして分子メカニズムの最前線-2011

    • Author(s)
      川口浩
    • Organizer
      第55回日本リウマチ学会総会
    • Place of Presentation
      神戸ポートピアホテル、兵庫(招待講演)
    • Year and Date
      2011-07-19
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] 軟骨細胞のNotch/Rbpj/Hes1シグナルは骨格形成および変形性関節症における軟骨内骨化の後期過程を制御する2011

    • Author(s)
      保坂陽子、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Transcriptional induction of ADAMTS5 by NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2011

    • Author(s)
      Kobayashi H, Kawaguchi H, et al.
    • Organizer
      International Osteoporosis Federation/Australian and New Zealand Bone & Mineral Society (IOF/ANZBMS)
    • Place of Presentation
      Gold coast (AUS)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] GSK-3αとGSK-3βは協調的にRelA/NF-κB p65のリン酸化を介して軟骨細胞初期分化を制御する2011

    • Author(s)
      伊藤祥三、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] NF-κBファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2011

    • Author(s)
      小林寛、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Functional Redundancy of GSK-3α and GSK-3β to Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011

    • Author(s)
      Itoh S, Kawaguchi H, et al.
    • Organizer
      Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Transcriptional induction of ADAMTS5 by NF_<-κ>Βfamily member RelA/p65 in chondrocytes during osteoarthritis development2011

    • Author(s)
      Kobayashi H, Hirata M, Itoh S, Saito T, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      2011 Gordon Research Conference : Cartilage Biology & Pathology
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Notch/Rbpj/Hes1 Signal in Chondrocytes Modulates the Terminal Stage of Endochondral Ossification during Skeletal Growth and Osteoarthritis Development2011

    • Author(s)
      Hosaka Y, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Transcriptional induction of ADAMTS5 by NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2011

    • Author(s)
      Kobayashi H, Kawaguchi H, et al.
    • Organizer
      International Osteoporosis Federation/Australian and New Zealand Bone & Mineral Society(IOF/ANZBMS)
    • Place of Presentation
      Gold coast (AUS)(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Transcriptional induction of ADAMTS5 by NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2011

    • Author(s)
      Kobayashi H, Kawaguchi H, et al.
    • Organizer
      International Osteoporosis Federation/Australian and New Zealand Bone & Mineral Society (IOF/ANZBMS)
    • Place of Presentation
      Gold coast (AUS)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] 変形性関節症up-to-date:その診断、治療、そして分子メカニズム研究の最前線-2011

    • Author(s)
      川口浩
    • Organizer
      第42回九州リウマチ学会
    • Place of Presentation
      熊本県立劇場、熊本(招待講演)
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] C/EBPb and RUNX2 Cooperatively Control Cartilage Degradation with MMP-13 as the Target and HIF-2a as the Inducer in Chondrocytes2011

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] Notch/Rbpj/Hes1 Signal in Chondrocytes Modulates the Terminal Stage of Endochondral Ossification during Skeletal Growth and Osteoarthritis Development2011

    • Author(s)
      Hosaka Y, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] 高齢化社会における運動器の健康-ロコモティブシンドローム-2011

    • Author(s)
      川口浩
    • Organizer
      第28回日本医学会総会
    • Place of Presentation
      (招待講演)(web開催)
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Overview of molecular backgrounds of osteoarthritis2011

    • Author(s)
      Kawaguchi H
    • Organizer
      The 3rd International Cartilage and Osteoarthritis Symposium(ICOA 2011)(Keynote Lecture)
    • Place of Presentation
      Suwon, Korea
    • Year and Date
      2011-07-05
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] 住民疫学調査ROADからみえてきた日本のOA2011

    • Author(s)
      吉村典子、村木重之、岡敬之、川口浩、中村耕三、阿久根徹
    • Organizer
      第56回 日本 リウマチ学会総会
    • Place of Presentation
      グラ ンドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Overview of molecular backgrounds of osteoarthritis2011

    • Author(s)
      Kawaguchi H
    • Organizer
      The 3rd International Cartilage and Osteoarthritis Symposium (ICOA 2011)
    • Place of Presentation
      Suwon, Korea(招待講演)
    • Year and Date
      2011-07-05
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBP-βand RUNX2 in chondrocytes control cartilage degradation2011

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Mabuchi A, Sapkota BR, Akune T, Yano F, Ikeda T, Nishida N, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
    • Organizer
      2011 Gordon Research Conference : Cartilage Biology & Pathology
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] 軟骨細胞のNotch/Rbpj/Hes1シグナルは骨格形成および変形性関節症における軟骨内骨化の後期過程を制御する2011

    • Author(s)
      保坂陽子、川口浩, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] C/EBPb and RUNX2 Cooperatively Control Cartilage Degradation with MMP-13 as the Target and HIF-2a as the Inducer in Chondrocytes2011

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      San Diego, USA(招待講演)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Endochondral ossification signals as potential therapeutic targets for osteoarthritis(Invited Lecture)2011

    • Author(s)
      Kawaguchi H
    • Organizer
      2011 Gordon Research Conference : Cartilage Biology & Pathology
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2011-03-08
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Functional Redundancy of GSK-3α and GSK-3βto Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011

    • Author(s)
      Itoh S, Kawaguchi H, et al.
    • Organizer
      Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      San Diego, USA(招待講演)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 変形性関節症治療の現状と未来:国際ガイドラインと治療標的分子の探索2011

    • Author(s)
      川口浩
    • Organizer
      第26回日本整形外科学会基礎学術集会
    • Place of Presentation
      ベイシア文化ホール、群馬(招待講演)
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] 大規模コホートにおける変形性膝関 節症と関節マーカー(パネルディスカッ ション:関節症マーカー・画像診断と関 節症の疫学).2011

    • Author(s)
      森田充浩、山田治基、吉村典子、伊達秀 樹、岡敬之、村木重之、阿久根徹、川口 浩
    • Organizer
      第40回 日本関節病学会
    • Place of Presentation
      鹿児島市民文化ホール、 鹿児島
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Functional Redundancy of GSK-3α and GSK-3β to Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011

    • Author(s)
      Itoh S, Kawaguchi H, et al.
    • Organizer
      Osteoarthritis Research Society International (OARSI)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-23390358
  • [Presentation] C/EBPb and RUNX2 Cooperatively Control Cartilage Degradation with MMP-13 as the Target and HIF-2a as the Inducer in Chondrocytes2011

    • Author(s)
      Hirata M, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] 骨粗鬆症の治療戦略up-to-date-骨形成促進剤の位置づけ-2011

    • Author(s)
      川口浩
    • Organizer
      第39回日本関節症学会
    • Place of Presentation
      パシフィコ横浜、神奈川(招待講演)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Notch/Rbpj/Hes1 Signal in Chondrocytes Modulates the Terminal Stage of Endochondral Ossification during Skeletal Growth and Osteoarthritis Development2011

    • Author(s)
      Hosaka Y, Kawaguchi H, et al.
    • Organizer
      The American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      San Diego, USA(招待講演)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] C/EBPb and RUNX2 Cooperatively Control Cartilage Degradation with MMP-13 as the Target and HIF-2a as the Inducer in Chondrocytes2011

    • Author(s)
      Hirata M, Kawaguchi H, et al
    • Organizer
      The American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Transcriptional induction of ADAMTS5 by NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development International Osteoporosis Federation2011

    • Author(s)
      Kobayashi H, Kawaguchi H, et al
    • Organizer
      Australian and New Zealand Bone & Mineral Society(IOF/ANZBMS)
    • Place of Presentation
      Gold coast(AUS)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Endochondral ossification signals as potential therapeutic targets for osteoarthritis(Invited Lecture)2011

    • Author(s)
      Kawaguchi H
    • Organizer
      2011 Gordon Research Conference
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] KOACADの臨床的意義(シンポジウム:OAの画像診断と評価).2011

    • Author(s)
      川口浩
    • Organizer
      第40回日本関節病学会
    • Place of Presentation
      鹿児島市民文化ホール、鹿児島
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] 単純X線画像における変形性膝関節症のコンピュータ支援 診断システムKOACADの臨床利用(パネル ディスカッション:関節症マーカー・画 像診断と関節症の疫学).2011

    • Author(s)
      岡敬之、川口浩、村木重之、阿久根徹、中村耕三、吉村典子
    • Organizer
      第40回 日本関節病学会
    • Place of Presentation
      鹿児島市民 文化ホール、鹿児島
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Overview of molecular backgrounds of osteoarthritis2011

    • Author(s)
      Kawaguchi H
    • Organizer
      The 3rd International Cartilage and Osteoar thritis Symposium(ICOA 2011)
    • Place of Presentation
      Suwon, Korea
    • Year and Date
      2011-07-05
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Functional Redundancy of GSK-3αand GSK-3βto Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011

    • Author(s)
      Itoh S, Kawaguchi H, et al
    • Organizer
      Osteoarthritis Research Society International(OARSI)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Overview of molecular backgrounds of osteoarthritis2011

    • Author(s)
      Kawaguchi H
    • Organizer
      The 3rd International Cartilage and Osteoarthritis Symposium (ICOA 2011)
    • Place of Presentation
      Suwon, Korea(招待講演)
    • Year and Date
      2011-07-05
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] C/EBP-βand RUNX2 cooperatively control cartilage degradation with MMP-13 as the target and HIF-αas the inducer in chondrocytes2011

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Mabuchi A, Sapkota BJ, Akune T, Yano F, Ikeda T, Nishida N, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Organizer
      33th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      San Diego, California, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteoarthritis (invited lecture).2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Therapeutic target molecules for cartilage degradation in osteoarthritis progression(Invited Lecture)2010

    • Author(s)
      Kawaguchi H
    • Organizer
      System Biology and Drug Discovery
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] HIF2A/NF-kappa B signal in chondrocytes controls extensive steps of osteoarthritis development in mice and humans(Young Investigator Award)2010

    • Author(s)
      Fukai A, Saito T, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Self-initiated surface graft polymerization of poly(2-methacryloyloxyethyl phosphorylcholine) on PEEK and carbon fiber reinforced PEEK for orthopaedic and spinal applications2010

    • Author(s)
      Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society (ORS)
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] A local application of recombinant human fibroblast growth factor-2 for tibial shaft ractures : A randomized, double-blind, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H
    • Organizer
      32th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteoarthritis(invited lecture)2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteoarthritis (invited lecture).2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis (OARSI).
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] A local application of recombinant human fibroblast growth factor-2 for tibial shaft ractures : A randomized, double-blind, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H
    • Organizer
      32th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteoarthritis.2010

    • Author(s)
      川口浩
    • Organizer
      2010 World Congress on Osteoarthritis (OARSI).
    • Place of Presentation
      Brussels, Belgium.
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] cGMP-dependent kinase II (cGKII)はGSK3βをリン酸化・不活化することによって軟骨細胞の肥大分化を制御する2010

    • Author(s)
      川崎洋介、釘宮典孝、筑田博隆、池田敏之、斎藤琢、矢野文子、中村耕三、鄭雄一、川口浩
    • Organizer
      第23回日本軟骨代謝学会
    • Place of Presentation
      鹿児島県医師会館、鹿児島
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Molecular backgrounds of cartilage degradation during osteoarthritis progression (Invited Lecture)2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 Anti-aging and Well-being International Symposium
    • Place of Presentation
      Daegu, Korea
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Endochondral ossification signal : A potential therapeutic torget for osteoarthritis(invited lecture).2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 Vorld Congress on Osteoarthritis(OARSI).
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Therapeutic target molecules for cartilage degradation in osteoarthritis progression.2010

    • Author(s)
      川口浩
    • Organizer
      System Biology and Drug Discovery.
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] A local application of recombinant human fibroblast growth factor-2 for tibial shaft ractures : A randomized, double-blind, placebo-controlled trial.2010

    • Author(s)
      Kawaguchi H
    • Organizer
      32th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Therapeutic target molecules for cartilage degradation in osteoarthritis progression (Invited Lecture)2010

    • Author(s)
      Kawaguchi H
    • Organizer
      System Biology and Drug Discovery
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Molecular backgrounds of cartilage degradation during osteoarthritis development.2010

    • Author(s)
      川口浩
    • Organizer
      第19回国際リウマチシンポジウム
    • Place of Presentation
      神戸ポートピアホテル、兵庫
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteoarthritis (invited lecture).2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis (OARSI).
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Molecular backgrounds of cartilage degradation during osteoarthritis progression(Invited Lecture)2010

    • Author(s)
      Kawaguchi H
    • Organizer
      2010 Anti-aging and Well-being International Symposium
    • Place of Presentation
      Daegu, Korea
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteo arthritis.2010

    • Author(s)
      Kawaguchi H, et al.
    • Organizer
      2010 World Congress on Osteoarthritis
    • Place of Presentation
      Brussels, Belgium
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Endochondral ossification signal : A potential therapeutic target for osteo arthritis.2010

    • Author(s)
      Kawaguchi H, et al.
    • Organizer
      2010 World Congress on Osteoarthritis
    • Place of Presentation
      Brussels, Belgium
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21591931
  • [Presentation] Molecular network on the C/EBP-beta axis including Runx2, MMP13, and HIF2A controls osteoarthritis development(Young Investigator Award).2010

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2010 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] 変形性関節症up-to-date-その診断、治療、そして分子メカニズム研究の最前線2010

    • Author(s)
      川口浩
    • Organizer
      第25回日本整形外科学会基礎学術集会
    • Place of Presentation
      国立京都国際会館、京都
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] 骨粗鬆症の治療戦略 up-to-date:骨折予防・骨強度の視点から2010

    • Author(s)
      川口浩
    • Organizer
      第83回日本整形外科学会学術総会
    • Place of Presentation
      東京国際フォーラム、東京
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during skeletal growth and osteophyte formation in osteoarthritis2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society (ORS)
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] A local application of recombinant human fibroblast growth factor-2 for tibial shaft ractures : A randomized, double-blind, placebo-controlled trial2010

    • Author(s)
      Kawaguchi H, Oka H, Jingushi S, Izumi T, Fukunaga M, Sato K, Matsushita T, and Nakamura K
    • Organizer
      32th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during skeletal growth and osteophyte formation in osteoarthritis2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society(ORS)
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Molecular backgrounds of cartilage degradation during osteoarthritis progression.2010

    • Author(s)
      川口浩
    • Organizer
      2010 Anti-aging and Well-being International Symposium.
    • Place of Presentation
      Daegu, Korea.
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] A randomized, double-blind, placebo-controlled trial of local application of recombinant human fibroblast growth factor-2 for tibial shaft fractures2010

    • Author(s)
      Kawaguchi H, Matsushita T, Oka H, Jingushi S, Izumi T, Fukunaga M, Sato K, Nakamura K
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society(ORS)
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] A Transcription factor p63 controls extensive steps of endochondral ossification through distinct functions of the isoforms(Young Investigator Award)2010

    • Author(s)
      Taniguchi Y, Saito T, Ikeda T, Chung UI, Nakamura H, Kawaguchi H
    • Organizer
      32th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Comprehensive control of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis progression2009

    • Author(s)
      Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 2nd International Cartilage and Osteoarthrit is Symposium(Plenary Lecture).
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 2nd International Cartilage and Osteoarthritis Symposium(Plenary Lecture)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Osteoarthritis, osteoporosis and cognitive impairment : the research on osteoarthritis/osteoporosis against disability study2009

    • Author(s)
      Yoshimura N. Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
    • Organizer
      36th European Symposium on Calcified Tissues (ECTS)
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      川口浩
    • Organizer
      The 35^<th> Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] 変形性関節症の診断と治療:最近の進歩(カトレア教育研修講演:Arthritis診断と治療 最新のトピックス)2009

    • Author(s)
      川口浩
    • Organizer
      第81回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional Regulation of Type X Collagen Expression and Hypertrophic Differentiation of Chondrocytes by Runx2 during Osteoarthritis Progression2009

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ikeda T, Kan A, Moro T, Ohba S, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      The 55th Annual Meeting of the Orthopaedic Research Society (ORS)
    • Place of Presentation
      Las Vegas, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrop by and skeletal growth.2009

    • Author(s)
      川口浩
    • Organizer
      4th international Conference on cGMP.
    • Place of Presentation
      Rosensburg, Germany
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 35th Annual Meeting of the Korean Orthopaedic Research Society.
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] High-density brush-like structure mimicking cartilage gives high durability to cross-linked polyethylene2009

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Organizer
      4th UHMWPE International Meeting
    • Place of Presentation
      Torino, Italy
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      川口浩
    • Organizer
      The 2nd International Cartilage and Osteoarthritis Symposium.
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] NF-kappa B family member RelA/p65, a transcription factor of Sox9, is essential for chondrogenic differentiation and skeletal growth (Young Investigator Award)2009

    • Author(s)
      Itoh S, Saito T, Ushita M, Ikeda T, Yano F, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Cross-linked brush-like structure of surface-modified layers gives high durability to joint replacement2009

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Yamawaki N, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Organizer
      22nd annual conference of the European Society for Biomaterials (ESB)
    • Place of Presentation
      Lausanne, Swiss
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 2nd International Cartilage and Osteoarthritis Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Health-related quality of life in subjects with vertebral fracture, knee osteoarthritis, lumbar spondylosis and other chronic diseases as well as low back pain and knee pain in a population-based cohort study in Japan : The ROAD study.2009

    • Author(s)
      Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症の診断と治療 : 最近の進歩2009

    • Author(s)
      川口浩
    • Organizer
      第81回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification.2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression (Special Lecture: OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      川口浩
    • Organizer
      The 35th Annual Meeting of the Korean Orthopaedic Research Society.
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth2009

    • Author(s)
      Kawaguchi H, Chikuda H, Kawasaki Y, Hofmann F
    • Organizer
      4th International Conference on cGMP
    • Place of Presentation
      Rosensburg, Germany
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Association of knee osteoarthritis, lumbar spondylosis and osteoporosis with mild cognitive impairment : The ROAD(Research on Osteoarthritis/osteoporosis Against Disability)study.2009

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression.2009

    • Author(s)
      Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth2009

    • Author(s)
      Kawaguchi H, Chikuda H, Kawasaki Y, Hofmann F
    • Organizer
      4th International Conference on cGMP
    • Place of Presentation
      Rosensburg, Germany
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Identification of receptor tyrosine kinase-like orphan receptor 2 (ROR2)/WNT5B signaling as a therapeutic target against osteosarcoma2009

    • Author(s)
      Morioka K, Matsuda K, Kawano H, Nakamura K, Kawaguchi H, Nakamura Y
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      Kawaguchi H
    • Organizer
      第18回国際リウマチシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      The 35^<th> Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] 変形性関節症の治療標的分子へのアプローチ2009

    • Author(s)
      川口浩
    • Organizer
      第82回日本生化学(シンポジウム「運動器形成・再生のための分子基盤」
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Notch/RBPJk/Hesl signaling controls terminal differentiation of chondrocytes during endochondral ossification.2009

    • Author(s)
      Hikata T, Saito T, Takaishi H, Akiyama H, Nakamura T, Yamaguchi A, Matsumoto M, Chiba K, Toyama Y, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Cyclic GMP-dependent protein kinase II promotes chondrocyte hypertrophy and skeletal growth.2009

    • Author(s)
      Kawaguchi H, Chikuda H, Kawasaki Y, Hofmann F
    • Organizer
      4th International Conference on cGMP.
    • Place of Presentation
      Rosensburg, Germany.
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium)2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 35th Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      The 35^<th> Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Cross-linked brush-like structure of surface-modified layers gives high durability to joint replacement2009

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Yamawaki N, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Organizer
      22nd Annual conference of the European Society for Biomaterials (ESB)
    • Place of Presentation
      Lausanne, Switzerland
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 2nd International Cartilage and Osteoarthritis Symposium (Plenary Lecture)
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Automated quantification and diagnosis of the knee on plain radiographs : The ROAD study.2009

    • Author(s)
      Oka H, Akune T, Muraki S, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression(Special Lecture : OARSI-KORS Co-sponsored Symposium).2009

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      The 35^<th> Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] A novel thienoindazole-derivative small compound induces chondrogenic differentiation without promoting hypertrophy through Runxl.2009

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Hojo H, Kimura A, Takeda S, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Association of radiographic severity of lumbar spondylosis with low back pain and related disabilities : The ROAD study2009

    • Author(s)
      Akune T, Muraki S, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Mouse genetics studies on molecular mechanisms underlying bone and cartilage disorders.2009

    • Author(s)
      Kawaguchi H
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society(ORS).
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression (Special Lecture : OARSI-KORS Co-sponsored Symposium)2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 35th Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Regulator of G protein signaling(RGS)-2 enhances bone anabolic action of PTH through inhibition of Gαq/PKC pathway in osteoblasts.2009

    • Author(s)
      Ogata N, Yano F, Chikazu D, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research(ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte formation in osteoarthritis2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症の疫学研究の現状と問題点:ROADプロジェクト(シンポジウム:OAの病態と診断)2009

    • Author(s)
      川口浩
    • Organizer
      第81回日本リウマチ学会総会・学術集会.
    • Place of Presentation
      グランドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] 変形性関節症の治療標的分子へのアプローチ.第82回日本生化学(シンポジウム「運動器形成・再生のための分子基盤」).2009

    • Author(s)
      川口浩
    • Organizer
      第82回日本生化学(シンポジウム「運動器形成・再生のための分子基盤」).
    • Place of Presentation
      神戸国際会議場、兵庫
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] 変形性関節症の治療標的分子へのアプローチ2009

    • Author(s)
      川口浩
    • Organizer
      第82回日本生化学(シンポジウム「運動器形成・再生のための分子基盤」)
    • Place of Presentation
      神戸国際会議場、兵庫
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Aktl in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis.2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Notch/RBPJk/Hes1 signaling controls terminal differentiation of chondrocytes during endochondral ossification2009

    • Author(s)
      Hikata T, Saito T, Takaishi H, Akiyama H, Nakamura T, Yamaguchi A, Matsumoto M, Chiba K, Toyama Y, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] cGKIIはGSK3βをリン酸化することによって軟骨細胞の肥大分化を制御する2009

    • Author(s)
      川崎洋介、釘宮典孝、筑田博隆、中村耕三、鄭雄一、川口浩
    • Organizer
      第82回日本整形外科学会学術総会
    • Place of Presentation
      福岡国際会議場、福岡
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Transcriptional regulation of cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      川口浩
    • Organizer
      The 2nd International Cartilage and Osteoarthrit is Symposium(Plenary Lecture).
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-21591930
  • [Presentation] Full-automatic quantification of hip geometry on plain radiographs by a novel computer-assisted system2009

    • Author(s)
      Oka H, Akune T, Muraki S, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      36th European Symposium on Calcified Tissues (ECTS)
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Regulator of G protein signaling (RGS)-2 enhances bone anabolic action of PTH through inhibition of Gαq/PKC pathway in osteoblasts2009

    • Author(s)
      Ogata N, Yano F, Chikazu D, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] ミニシンポジウム「骨のバイオマテリアルと医工連携」2009

    • Author(s)
      茂呂徹, 高取吉雄, 石原一彦, 山脇昇, 京本政之, 川口浩
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Molecular backgrounds of cartilage degeneration during os teoarthritis progression (Special Lecture : OARSI-KORS Cosponsored Symposium)2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 35^<th> Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] A novel thienoindazole-derivative small compound induces chondrogenic differentiation without promoting hypertrophy through Runx1 (Young Investigator Award)2009

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Hojo H, Kimura A, Takeda S, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Automated quantification and diagnosis of the knee on plain radiographs : The ROAD study2009

    • Author(s)
      Oka H, Akune T, Muraki S, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症の疫学研究の現状と問題点:ROADプロジェクト(シンポジウム:OAの病態と診断)2009

    • Author(s)
      川口浩、阿久根徹、岡敬之、村木重之、中村耕三、吉村典子
    • Organizer
      第81回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Requirement of Runx1 for chondrocyte lineage commitment2009

    • Author(s)
      Kimura A, Inose H, Fujita K, Yano F, Kawaguchi H, Chung UI, Shinomiya K, Takeda S
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Mouse genetics studies on molecular mechanisms underlying bone and cartilage disorders (Kappa Delta Award Paper Presentation)2009

    • Author(s)
      Kawaguchi H, Akune T, Yamada T, Ogata N
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society (ORS)
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      川口浩
    • Organizer
      第18回国際リウマチシンポジウム
    • Place of Presentation
      グランドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] 変形性関節症の治療標的分子へのアプローチ2009

    • Author(s)
      川口浩
    • Organizer
      第82回 日本生化学 (シンポジウム「運動器形成・再生のための分子基盤」)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症の診断と治療:最近の進歩(カトレア教育研修講演:Arthritis診断と治療最新のトピックス).2009

    • Author(s)
      川口浩
    • Organizer
      第81回日本リウマチ学会総会・学術集会
    • Place of Presentation
      グランドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Brush-like structure only gives high durability to cross-linked polyethylene among various surface-modified layers with MPC polymer2009

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Organizer
      The 55th Annual Meeting of the Orthopaedic Research Society (ORS)
    • Place of Presentation
      Las Vegas, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression2009

    • Author(s)
      Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Association of knee osteoarthritis, lumbar spondylosis and osteoporosis with mild cognitive impairment : The ROAD (Research on Osteoarthritis/osteoporosis Against Disability) study2009

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      川口浩
    • Organizer
      第18回国際リウマチシンポジウム.
    • Place of Presentation
      グランドプリンスホテル新高輪、東京
    • Data Source
      KAKENHI-PROJECT-21659348
  • [Presentation] Molecular backgrounds of cartilage degeneration during osteoarthritis progression.2009

    • Author(s)
      Kawaguchi H
    • Organizer
      The 35th Annual Meeting of the Korean Orthopaedic Research Society
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Health-related quality of life in subjects with vertebral fracture, knee osteoarthritis, lumbar spondylosis and other chronic diseases as well as low back pain and knee pain in a population-based cohort study in Japan : The ROAD study2009

    • Author(s)
      Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] NF-kappa B family member RelA/p65, a transcription factor of Sox9, is essential for chondrogenic differentiation and skeletal growth.2009

    • Author(s)
      Itoh S, Saito T, Ushita M, Ikeda T, Yano F, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症の診断と治療:最近の進歩2009

    • Author(s)
      川口浩
    • Organizer
      第81回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症up-to-date:その病態解明・診断・治療の最前線2008

    • Author(s)
      川口浩
    • Organizer
      第81回日本整形外科学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Hypoxia-inducible factor 2A (HIF2A) controls sequential steps in the late stage of endochondral ossification (Young Investigator Award)2008

    • Author(s)
      Saito T, Ikeda T, Kan A, Hirata M, Fukai A, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症:研究・診療の現状と問題点2008

    • Author(s)
      川口浩
    • Organizer
      第50回日本老年医学会学術集会・総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Transcriptional regulation of osteoarthritis progression2008

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      The 13th Congress of the Asia Pacific League of Associatjons for Rheumatology (APLAR 2008).
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-18659436
  • [Presentation] Transcriptional regulation of osteoarthritis progression2008

    • Author(s)
      Kawaguchi H
    • Organizer
      The 13th Congress of the Asia Pacific League of Associations for Rheumatology (APLAR 2008).
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症:その病態解明・診断・治療の最前線2008

    • Author(s)
      川口浩
    • Organizer
      福岡県臨床整形外科医会
    • Place of Presentation
      福岡
    • Year and Date
      2008-06-07
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性膝関節症 : その課題とアプローチの現状 (プレナリーレクチャー)2008

    • Author(s)
      中村耕三, 川口浩, 吉村典子, 阿久根徹, 岡敬之, 村木重之, 馬淵昭彦
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      北海道厚生年金会館、北海道
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of osteoarthritis progression2008

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      The 13th Congress of the Asia Pacific League of Associlations for Rheumatology(APLAR 2008)
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] 変形性関節症研究の現状(ランチョンセミナー)2008

    • Author(s)
      川口浩
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      北海道
    • Year and Date
      2008-04-20
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症up-to-date:診断と治療の最前線2008

    • Author(s)
      川口浩
    • Organizer
      第1回TCOA(東京都臨床整形外科医会)up-to-dateセミナ一
    • Place of Presentation
      東京
    • Year and Date
      2008-08-30
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 糖代謝・脂質代謝シグナルによる骨代謝制御2008

    • Author(s)
      川口浩
    • Organizer
      第18回中図・四国骨代謝研究会
    • Place of Presentation
      岡山
    • Year and Date
      2008-07-12
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症の大規模臨床統合データベースの構築と、これを用いた観察疫学・ゲノム疫学研究(シンポジウム:学術プロジェクト課題の研究成果報告)2008

    • Author(s)
      川口浩
    • Organizer
      第81回日本整形外科学会学術総会
    • Place of Presentation
      北海道
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] β-catenin directly binds to a specifc intracellular domain of PTH/PTHrP receptor and regulates the signaling in chondrocytes during endochondral ossification. (President's Award)2008

    • Author(s)
      Yano F, Chung UI, Ikeda T, Kawasaki Y, Kawaguchi H, Tawfeek HAW, Mahon MJ, Segre GV, Ogata N
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of osteoarthritis progression (Symposium: Update on Osteoarthritis : from Bench to Bedside -APLAR-OARSI Co-Sponsored Symposium).2008

    • Author(s)
      川口浩
    • Organizer
      The 13th Congress of the Asia Pacific League of Associations for Rheumatology (APLAR 2008).
    • Place of Presentation
      Yokohama, Japan.
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] Lateral joint space narrowing on radiographs predicts pain progression in knee osteoarthritis patients : Application of fully automatic KOACAD system to OAI public data2008

    • Author(s)
      Oka H, Akune T, Muraki S, Nakamura K, Yoshimura N, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Advanced wear resistance of MPC grafted surface with various phosphate density on cross-linked polyethylene2008

    • Author(s)
      Kyomoto M, Moro T, Konno T, Kawaguchi H, Takatori Y, Nakamura K, Miyaji F, Yamawaki N, Ishihara K
    • Organizer
      54th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] C/EBPβ/p57^<Kip2> signaling maintains transition from proliferation to hypertrophic differentiation of chondrocytes during skeletal growth2008

    • Author(s)
      Hirata M, Kugimiya F, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBP-beta promotes hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2> during endochonderal ossification (Young Investigator Award)2008

    • Author(s)
      Kugimiya F, Hirata M, Ohba S, Kawamura K, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症の疫学研究の現状と問題点:ROAD (Research on Osteoarthritis against Disabilit)プロジェクト(シンポジウム:変形性膝関節症のマネージメント-最新の臨床エビデンスとエキスパートオピニオン-)2008

    • Author(s)
      川口浩、岡敬之、村木重之、阿久根徹、馬淵昭彦、吉村典子、中村耕三
    • Organizer
      第81回日本整形外科学会学術総会
    • Place of Presentation
      北海道厚生年金会館、北海道
    • Data Source
      KAKENHI-PROJECT-20591775
  • [Presentation] 変形性関節症研究の現状と問題点(シンポジウム:プロテオーム解析技術の新展開:創薬ターゲット/臨床マーカー発見を目指して)2008

    • Author(s)
      川口浩
    • Organizer
      日本ヒトプロテオーム機構第6回大会
    • Place of Presentation
      大阪
    • Year and Date
      2008-07-29
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症研究の現状と問題点2008

    • Author(s)
      川口浩
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Evaluation of the usefulness of biomarkers in knee osteoarthritis or lumbar spondylosis in mass cohort study of Japan2008

    • Author(s)
      Morita M, Yamada H, Yoshimura N, Date H, Oka H, Muraki S, Akune T, Ichinose H, Kawaguchi H, Nakamura K
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of a transcription factor p63 for transactivation of Wnt9a and Gdf5 causing joint cartilage formation2008

    • Author(s)
      Kan A, Ikeda T, Saito T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of osteoarthritis progression (Symposium: Update on Osteoarthritis: from Bench to Beside - APLAR-OARSI Co-Sponsored Symposium).2008

    • Author(s)
      Kawaguchi H
    • Organizer
      The 13th Cohgress of the Asia Pacific League of Associations for Rheumitology(APLAR 2008)
    • Place of Presentation
      Yokohama
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症の疫学研究の現状と問題点:ROAD(Research on Osteoarthritis against Disabilit)プロジェクト(シンポジウム:変形性膝関節症のマネージメント- 最新の臨床エビデンスとエキスパートオピニオン-)2008

    • Author(s)
      川口浩
    • Organizer
      第81回日本整形外科学会学術総会
    • Place of Presentation
      北海道
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Association of radiographic severity of knee osteoarthritis with symptomatic parameters : The ROAD study2008

    • Author(s)
      Akune T, Muraki S, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Prevalence and risk factors for radiographic osteoarthritis of the knee and lumbar spine in Japan : The Research on Osteoarthritis Against Disability (ROAD) Study2008

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Akune T, Mabuchi A, En-yo Y, Yoshida M, Suzuki T, Yoshida H, Kawaguchi H, Nakamura K
    • Organizer
      35th European Symposium on Calcified Tissues (ECTS)
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] A Novel small thienoindazole-derivative compound promotes chondrogenic differentiation without inducing hypertrophy through production of Runx1 (Young Investigator Award)2008

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Biocompatible phospholipid polymer grafting on liner surface of artificial hip joints enhances the wear resistance independently of liner cross-link or femoral head material2008

    • Author(s)
      Moro T, Takatori Y, Kyomoto M, Ishihara K, Nakamura K, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 変形性関節症研究の現状と問題点(シンポジウム:変形性関節症研究の基礎と臨床)2008

    • Author(s)
      川口浩
    • Organizer
      第52回日本リウマチ学会総会・学術集会
    • Place of Presentation
      北海道
    • Year and Date
      2008-04-20
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regul ation of osteoarthritis progression2008

    • Author(s)
      Kawaguchi H
    • Organizer
      The 13th Congress of the Asia Pacif is League of Associations for Rheuma tology (APLAR 2008)
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] Development of high-throughput screening system for osteogenic drugs using cell-based sensor2008

    • Author(s)
      Hojo H, Igawa K, Ohba S, Yano F, Nakajima K, Komiyama K, Yonezawa T, Woo JT, Lichtler AC, Rowe DW, Ikeda T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 研究・診療の現状と問題点(シンポジウム:骨粗鬆症と変形性関節症:研究と診療の最前線)2008

    • Author(s)
      川口浩
    • Organizer
      第50回日本考年医学会学術集会・総会
    • Place of Presentation
      千葉
    • Year and Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Akt1 contributes to chondrocyte calcification during endochondral ossification2008

    • Author(s)
      Fukai A, Kawamura N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Predictive capacity of biochemical markers of bone turnover and endogenous hormones for osteoporosis in men : ten-year follow-up of a Japanese cohort2008

    • Author(s)
      Yoshimura N, Oka H, Muraki S, Akune T, Kawaguchi H, Nakamura K
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of osteoarthritis progression (Symposium : Update on Osteoarthritis : from Bench to Bedside -APLAR-OARSI Co-Sponsored Symposium)2008

    • Author(s)
      Kawaguchi H
    • Organizer
      The 13th Congress of the Asia Pacific League of Associations for Rheumatology (APLAR 2008)
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Insulin/IRS/Akt signaling for maintainance of bone mass and turnover. (Symposia : Mediators of PTH action)2007

    • Author(s)
      Kawaguchi H
    • Organizer
      The Endocrine Society's 89th Annual Meeting (ENDO 07)
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 plays a central role in cartilage development by directly regulating key genes for chondrogenesis2007

    • Author(s)
      Ikeda T, Kawaguchi H, Saito T, Kan A, Yano F, Ushita M, Kawasaki Y, Nakamura K, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional induction of type X collagen expression and hypertrophic differentiation of chondrocytes by Runx2 during osteoarthritis progression (Young Investigator Award)2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 永久軟骨を再生させるための軟骨細胞増殖・基質産生培養法の開発とその作用機序 : ワークショップ112007

    • Author(s)
      星和人、中村耕三、川口浩
    • Organizer
      軟骨の変性と再生機序 : 第51回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2007-04-29
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] Transcriptional regulation of cartilage degeneration from amouse OA model (invited lecture).2007

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft.Lauderdale,Florida,USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Cartilage differentiation and osteoarthritis2007

    • Author(s)
      Kawaguchi H
    • Organizer
      19th Annual Meeting of the Korean Society for Molecular Cell Biology
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Local application of recombinant human fibroblast growth factor-2 on bone repair2007

    • Author(s)
      Kawaguchi H
    • Organizer
      The 6th Combined Meeting of the Orthopaedic Research Societies
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of sorting nexin 19 as a novel chondrogenic factor by a real-time fluorescence monitoring cell line ATDC5-S2RD5 (Young Investigator Award)2007

    • Author(s)
      Kan A, Ikeda T, Saito T, Ushita M, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of cartilage degeneration from a mouse OA model2007

    • Author(s)
      Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis. Ft.
    • Place of Presentation
      Lauderdale, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症研究の現状と限界.2007

    • Author(s)
      川口 浩, ほか
    • Organizer
      第25日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Is osteoporosis related to future incidence of osteoarthritis over 10 years, or vice-versa?2007

    • Author(s)
      Yoshimura N, Muraki S, Oka H, Mabuchi A, Kawaguchi H, Nakamura K
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of cartilage degeneration from a mouse OA model(invited lecture)2007

    • Author(s)
      Hiroshi Kawaguchi
    • Organizer
      2007 World Congress on Osteoarthritis(OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Presentation] 糖代謝と骨代謝に関連するAktシグナル2007

    • Author(s)
      川口浩、河村直洋、緒方直史、阿久根徹、山口雅之、星和人、門脇孝、中村耕三
    • Organizer
      生活習慣と骨代謝 : 第25回日本骨代謝学会学術集会
    • Place of Presentation
      大阪府大阪市
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] 変形性関節症2007

    • Author(s)
      川口 浩
    • Organizer
      第4回六甲カンファレンス
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Fully automatic quantification of knee osteoarthritis severity on standard radiographs by a novel computer-assisted system2007

    • Author(s)
      Oka H, Yoshimura N, Muraki S, Mabuchi A, Nakamura K, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of catilage degeneration from a mouse OA model2007

    • Author(s)
      Kawaguchi H
    • Organizer
      2007 World Congress on Oseroarthritis
    • Place of Presentation
      Ft.Lauderdale,USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Moleculat backgrounds of degererativer skeletal disorders from mouse genetics approach2007

    • Author(s)
      Kawaguchi H, et. al.
    • Organizer
      4th Meeting of Bone Biology Forum
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] マウスジェネティクスを用いた変形性関節症の分子メカニズムの解明 (シンポジウム : 骨・軟骨疾患の分子生物学)2007

    • Author(s)
      川口浩
    • Organizer
      第30回日本分子生物学会・第80回日本生化学学会 合同大会 (BMB2007)
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Association of radiographic osteoarthritis of knee and lumbar spine with pain. The Research on Osteoarthritis Against Disability (ROAD) study2007

    • Author(s)
      Muraki S, Yoshimura N, Oka H, Mabuchi A, En-Yo Y, Yoshida M, Saika A, Suzuka T, Yoshida H, Ishibashi H, Yamamoto S, Kawaguchi H, Nakamura K
    • Organizer
      34th annual meeting of the European Calcified Tissue Society (ECTS)
    • Place of Presentation
      Copenhagen, Denmark
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] GSK-3β inhibits osteoblastic bone formation through suppression of Runx2 transcriptional activity by the phosphorylation at a specific site (Young Investigator Award)2007

    • Author(s)
      Hirata M, Kugimiya F, Kawamura N, Ohba S, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Insulin/IRS/Akt signaling for maintainance of bone mass and turnover.2007

    • Author(s)
      kawaguchi H
    • Organizer
      The Endocrine Society's 89th Annual Meeting (ENDO 07)
    • Place of Presentation
      Toronto, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390411
  • [Presentation] Prevalence of radiographic osteoarthritis of knee and lumbar spine and its association with pain : The Research on Osteoarthritis Against Disability (ROAD) study2007

    • Author(s)
      Muraki S, Yoshimura N, Oka H, Mabuchi A, En-yo Y, Yoshida M, Suzuki T, Yoshida H, Ishibashi H, Yamamoto S, Kawaguchi H, Nakamura K
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of cartilage degeneration from a mouse OA model (invited lecture)2007

    • Author(s)
      Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Risk factors for radiographic knee osteoarthritis and lumbar spomdylosis : the ROAD study (Young Investigator Award)2007

    • Author(s)
      Muraki S, Oka H, Mabuchi A, En-yo Y, Yoshida M, Saiga A, Nakamura K, Kawaguchi H, Yoshimura N
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of type X collagen by Runx2 : Molecular network underlying chondrocyte hypertrophy causing osteoarthritis2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Runx1, co-activator of Sox5, Sox6 and Sox9 (the Sox trio) regulates chondrogenic differentiation2007

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Takeda S, Kimura A, Ohba S, Kugimiya F, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Cartilage differentiation and osteoarthritis2007

    • Author(s)
      Kawaguchi H
    • Organizer
      19th Annual Meeting of the Korean Society for Molrcular Cell Biology
    • Place of Presentation
      Seoul,Korea
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] マウスジェネティクスからの骨・関節疾患の分子メカニズムの解明2007

    • Author(s)
      川口 浩, ほか
    • Organizer
      宮崎大学大学院セミナー
    • Place of Presentation
      宮崎
    • Year and Date
      2007-06-25
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 変形性関節症up-to-date:その研究の新世紀2007

    • Author(s)
      川口 浩
    • Organizer
      南河内関節症研究会
    • Place of Presentation
      大阪
    • Year and Date
      2007-09-22
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Transcriptional regulation of type X collagen by Runx2 : Molecular network underlying chondrocyte hypertrophy causing osteoarthritis2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] マウスジェネティクスを用いた変形性関節症の分子ヂカニズムの解明.2007

    • Author(s)
      川口 浩, ほか
    • Organizer
      第80会日本整形外料学会学術総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Cartilage differentiation and osteoarthritis2007

    • Author(s)
      Kawaguchi H
    • Organizer
      19th Annual Meeting of the Korean Society for Molecular Cell Biology (Symposium : Cartilage and Bone)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Nano-scale modification with 2-methacryloyloxyethyl phosphorylcholine polymer brings to ultra-longevity for orthopaedic bearing2007

    • Author(s)
      Kyomoto M, Moro T, Miyaji F, Hashimoto M, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K
    • Organizer
      3rd UHMWPE International Meeting
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Full-automatic measurement of knee osteoarthritis parameters by a novel computer-assisted system on standard radiographs2007

    • Author(s)
      Oka H, Yoshimura N, Muraki S, Mabuchi A, Nakamura K, Kawaguchi H
    • Organizer
      1st Workshops on Imaging-Based Measures of Osteoarthritis
    • Place of Presentation
      Salzburg & Ainring, Germany
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Molecular basis of osteoarthritis from mouse genetics approach2007

    • Author(s)
      Kawaguchi H, et. al.
    • Organizer
      第16回国際リウマチシンポジウム
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] マウスジェネティクスを用いた変形性関節症の分子メカニズムの解明2007

    • Author(s)
      川口 浩
    • Organizer
      第30回日本分子生物学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Intra-articular osteoclastogenesis inhibitory factor/ostepprotegerin prevents cartilage degeneration in a murine model of osteoarthritis2007

    • Author(s)
      Shimizu S, Asou Y, Itoh S, Chung UI, Kawaguchi H, Shinomiya K, Muneta T
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Honolulu, USA
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] Transcriptional induction of SOX9 by NF-κB subunit p65 during chondrogenesis2007

    • Author(s)
      Ushita M, Ikeda T, Saito T, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Hypoxia-inducible factor 2α induces type X collagen and promotes hypertrophic differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Higashikawa A, Kawasaki Y, Kan A, Ushita M, Ohba S, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 関節軟骨再生の現状と展望 : シンポジウム32007

    • Author(s)
      星和人、川口浩、鄭雄一、高戸毅、中村耕三
    • Organizer
      骨関節老化の基礎と臨床 : 第9回日本骨粗鬆症学会
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2007-11-14
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] Identification of a novel chondrogenic factor Sorting Nexin 19 using a real-time fluorescence monitoring cell line ATDC5-S2RD52007

    • Author(s)
      Kan A, Ikeda T, Saito T, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] 関節の痛み・骨の痛み2007

    • Author(s)
      川口 浩, ほか
    • Organizer
      2007ゼリアパール会
    • Place of Presentation
      横浜
    • Year and Date
      2007-07-08
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] transcriptional regulation of cartilage degeneration during osteoarthriris2007

    • Author(s)
      Kawaguchi H
    • Organizer
      The 2007 International Symposiym-Wotkshop on Advanced Bone and Joint Science
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390388
  • [Presentation] 糖代謝・脂質代謝調節分子による骨代謝制御 : マウスジェネティクスからのアプローチ : シンポジウム62007

    • Author(s)
      川口浩、阿久根徹、緒方直史、星和人、篠田裕介、河村直洋、山口雅之、鄭雄一、門脇孝、中村耕三
    • Organizer
      骨粗鬆症と骨関節疾患の遺伝学 : 第9回日本骨粗鬆症学会
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2007-11-16
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] 自家軟骨細胞から大量永久軟骨再生のための最適シグナル条件の系統的・網羅的検索2006

    • Author(s)
      星和人、劉光耀、小笠原徹、浅輪幸世、高橋嗣明、鄭雄一、高戸毅、中村耕三、川口浩
    • Organizer
      第24回日本骨代謝学会学術集会
    • Place of Presentation
      東京都江東区
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] Bone metabolism regulation by lipid and sugar-metabolizing regulator2006

    • Author(s)
      Kawaguchi H
    • Organizer
      24th Annual Meeting of the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390530
  • [Presentation] 糖代謝、脂質代謝調節分子による骨代謝制御2006

    • Author(s)
      川口浩、阿久根徹、緒方直史、星和人、篠田裕介、河村直洋、山口雅之、鄭雄一、門脇孝、中村耕三
    • Organizer
      第24回日本骨代謝学会学術集会
    • Place of Presentation
      東京都江東区
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] 永久軟骨を再生させるための軟骨細胞再分化誘導法の検討と作用機序の解明2006

    • Author(s)
      星和人、鄭雄一、中村耕三、川口浩
    • Organizer
      第21回日本整形外科学会基礎学術集会
    • Place of Presentation
      長崎県長崎市
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] Optimal Combination of Soluble Factors for Tissue Engineering of Permanent Cartilage with High Quality and Quantity from Autologous Human Chondrocytes2006

    • Author(s)
      Hoshi K, Liu G, Ogasawara T, Asawa Y, Takahashi T, Yamaoka U, Chung UI, Takato T, Nakamura K, Kawaguchi H
    • Organizer
      ASBMR 28^<th> Annual Meeting
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Data Source
      KAKENHI-PROJECT-18390407
  • [Presentation] 糖代謝:脂質代謝調節分子による骨代謝制御.2006

    • Author(s)
      川口 浩
    • Organizer
      第24回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390530
  • [Presentation] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2005

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata. N, Akune T, Kadowaki T, Takeuchi Y, Fukumoto S, Hoshi K, Chung U, Nakamura K, Kawaguchi H
    • Organizer
      27th annual meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Nashville, Tennessee, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Presentation] NF-κB family member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, , Hosaka Y, Akiyama H, Chung UI, Kawaguchi H.
    • Organizer
      ASBMR 2013, American Society for Bone and Mineral Research
    • Place of Presentation
      Boltimore, USA
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] NF-κB family member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, , Hosaka Y, Akiyama H, Chung UI, Kawaguchi H.
    • Organizer
      2013 Osteoarthritis Research Society International (OARSI) World Congress.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] Osteo-chondrogenic function of BMP isdirected toward osteogenesis by Hh-Gli1 in the perichondrium.

    • Author(s)
      Hojo H, Ohba S, Taniguchi K, Shirai M,Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI
    • Organizer
      2012 American Society for Bone and Mineral Research (ASBMR).2012. 10.12-15 (Minneaplis, Minnesota, USA).
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Gli1 participates in the Indian Hedgehog-mediated osteogenesis during endochondral ossification. 2012 American Society for Bone and Mineral Research (ASBMR).

    • Author(s)
      Hojo H, Ohba S, Yano F, Saito T, Ikeda T,Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      2012. 10.12-15 (Minneaplis, Minnesota, USA).
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] Identification of fibroblast growth factor-18 as a molecule to protect and regenerate articular cartilage.

    • Author(s)
      Mori Y, Saito T, Ladel CH, Guehring H, Chung UI, Kawaguchi H
    • Organizer
      2013 Osteoarthritis Research Society International (OARSI) World Congress.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Presentation] NF-κBファミリーメンバーRelA/p65は、軟骨細胞のアポトーシスを阻害することで、骨格形成と変形性関節症の進行を制御する.

    • Author(s)
      小林寛、平田真、伊藤祥三、斎藤琢、鄭雄一、中村耕三、川口浩
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] NF-κBファミリーメンバーRelA/p65は、軟骨細胞のアポトーシスを阻害することで、骨格形成と変形性関節症の進行を制御する.

    • Author(s)
      小林寛、平田真、伊藤祥三、斎藤琢、鄭雄一、中村耕三、川口浩
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Presentation] Rbpj-dependent Notch signaling in chondrocytes modulates endochondral ossification during osteoarthritis development through transcriptional induction by Hes1 (Young Investigator Award).

    • Author(s)
      Sugita S, Hosaka Y, Saito T, Akiyama H, Chung UI, Kawaguchi H
    • Organizer
      2012 American Society for Bone and Mineral Research (ASBMR).2012. 10.12-15 (Minneaplis, Minnesota, USA).
    • Data Source
      KAKENHI-PROJECT-22249056
  • [Presentation] NF-κB family member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, , Hosaka Y, Akiyama H, Chung UI, Kawaguchi H.
    • Organizer
      2013 Osteoarthritis Research Society International (OARSI) World Congress.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Presentation] NF-κB family member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.

    • Author(s)
      Kobayashi H, Hirata M, Saito T, Itoh S, , Hosaka Y, Akiyama H, Chung UI, Kawaguchi H..
    • Organizer
      ASBMR 2013, American Society for Bone and Mineral Research
    • Place of Presentation
      Boltimore, USA
    • Data Source
      KAKENHI-PROJECT-24592253
  • [Presentation] Identification of fibroblast growth factor-18 as a molecule to protect and regenerate articular cartilage.

    • Author(s)
      Mori Y, Saito T, Ladel CH, Guehring H, Chung UI, Kawaguchi H
    • Organizer
      2013 Osteoarthritis Research Society International (OARSI) World Congress.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-25253087
  • [Presentation] RBPjκ-dependent Notch signaling in chondrocytes modulates skeletal growth and osteoarthritis development.

    • Author(s)
      Hosaka Y, Saito T, Sugita S, Fukai A, Hikata T, Akiyama H, Nakamura T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases. 2012. 6. 11-15 (Suzhou, China).
    • Data Source
      KAKENHI-PROJECT-22249056
  • []

  • []

  • 1.  NAKAMURA Kozo (60126133)
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    # of Collaborated Products: 141 results
  • 2.  CHUNG Ung-Il (30345053)
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    # of Collaborated Products: 102 results
  • 3.  HOSHI Kazuto (30344451)
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    # of Collaborated Products: 19 results
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  • 5.  IKEDA Toshiyuki (80322759)
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  • 14.  TAKATORI Yoshio (40179461)
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  • 27.  MIURA Toshiki (20376479)
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  • 38.  KONO Shinjiro (40333463)
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    # of Collaborated Projects: 1 results
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  • 84.  森 芳久 (60343141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 85.  米田 嘉重郎 (90074533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 86.  片桐 岳信 (80245802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  真鍋 一郎 (70359628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 88.  釘宮 典孝 (40447389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 89.  岡野 光夫 (00130237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 90.  大和 雅之 (40267117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 91.  中山 修一 (80401066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 92.  唐司 寿一 (40597762)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 93.  森崎 裕 (30508099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 94.  乾 洋 (60583119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 95.  福井 尚志 (10251258)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 96.  五嶋 孝博 (20272544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 97.  村上 誠 (60276607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 98.  工藤 一郎 (30134612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 99.  山本 寛 (10361487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 100.  KAMAL Bose
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 101.  MAHMAD Shah
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 102.  REUNG P.C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 103.  BOSE Kamal
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 104.  小林 篤樹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 105.  中澤 興三
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 106.  瀧川 順庸
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 107.  大賀 栄次郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 108.  OHGA Fujiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 109.  TAKETOMI Shuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 110.  吉村 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 111.  平田 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 112.  村木 重之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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