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Yanagisawa Hiromi  柳沢 裕美

Researcher Number 40746301
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7576-9186
Affiliation (Current) 2025: 筑波大学, 生存ダイナミクス研究センター, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 筑波大学, 生存ダイナミクス研究センター, 教授
2016 – 2017: 筑波大学, 生命領域学際研究センター, 教授
Review Section/Research Field
Principal Investigator
Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Basic Section 44020:Developmental biology-related / Cardiovascular medicine
Keywords
Principal Investigator
血管平滑筋細胞 / 細胞外マトリクス / 大動脈解離 / 大動脈瘤 / マウスモデル / 弾性線維 / メカニカルストレス / 平滑筋細胞 / ECM / ナノパーティクル … More / 内皮細胞 / 血管平滑筋 / 胸部大動脈 / 細胞外マトリックス / 微小領域RNAシークエンス / 細胞外基質 / モデルマウス / 電顕 / 結合実験 / シグナリング / シンクロトロンイメージング / ハイブリッドドメイン / ミクロフィブリル / メカ二カルストレス / 破裂 / トロンボスポンディン1 / 血管内皮細胞 / 大動脈瘤破裂 / トロンボスポンディン / ラベルフリーイメージング / ラマン分光法 / ラベルフリー / ラマンイメージング / 破裂予測 / メカノトランスダクション / 大動脈破裂 / 分子生物学 / 大血管外科学 / マトリセルラータンパク / メカノセンサー / アクチン / シグナル伝達 / フィブリン4 / 血管平滑筋細胞’ / マトリセルラータンパク質 / アクチン線維 / 膠原線維 … More
Except Principal Investigator
細胞外マトリックス / メカニカルストレス / 大動脈壁シアストレス / メカノトランスダクション / bicuspid aortopathy / 大動脈二尖弁 / 生体イメージング / 遺伝子改変マウス / 皮膚再生 / ニッチ / 力学的環境 / 領域化 / 細胞外マトリクス / 皮膚老化 / 三次元培養 / 細胞外環境 / 幹細胞不均一性 / 表皮幹細胞 / 血管平滑筋細胞 / TGF-β / 大動脈瘤破裂 / TGFβ / 大動脈瘤 Less
  • Research Projects

    (7 results)
  • Research Products

    (114 results)
  • Co-Researchers

    (25 People)
  •  Elucidation of the mechanism of thoracic aortic disease based on extracellular matrix and development of novel therapeutic strategyPrincipal Investigator

    • Principal Investigator
      柳沢 裕美
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      University of Tsukuba
  •  Mechanotransduction in bicuspid aortopathy

    • Principal Investigator
      徳永 千穂
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Saitama Medical University
  •  Elucidation of the pathogenesis of aortic dissection caused by the alteration in microfibrilsPrincipal Investigator

    • Principal Investigator
      柳沢 裕美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      University of Tsukuba
  •  Compartmentalization of epithelial stem cells in skin development and homeostasis

    • Principal Investigator
      Sada Aiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44020:Developmental biology-related
    • Research Institution
      Kyushu University
      Kumamoto University
  •  Elucidation of the mechanism of aortic aneurysm development based on mechanotransduction and prediction of aortic aneurysm rupturePrincipal Investigator

    • Principal Investigator
      Yanagisawa Hiromi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      University of Tsukuba
  •  Altered response to mechanical stress and aortic aneurysm developmentPrincipal Investigator

    • Principal Investigator
      Yanagisawa Hiromi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      University of Tsukuba
  •  TGFb signaling pathways involved in rupture of aortic aneurysms

    • Principal Investigator
      YAMASHIRO Yoshito
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      University of Tsukuba

All 2024 2023 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation

  • [Journal Article] Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with other cardiovascular diseases2024

    • Author(s)
      Torimoto Keiichi、Elliott Katherine、Nakayama Yuki、Yanagisawa Hiromi、Eguchi Satoru
    • Journal Title

      Cardiovascular Research

      Volume: - Issue: 6 Pages: 17-33

    • DOI

      10.1093/cvr/cvae044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-23H00431
  • [Journal Article] Unraveling the role of TGFβ signaling in thoracic aortic aneurysm and dissection using Fbn1 mutant mouse models2023

    • Author(s)
      Deleeuw Violette、Carlson Eric、Renard Marjolijn、Zientek Keith D.、Wilmarth Phillip A.、Reddy Ashok P.、Manalo Elise C.、Tufa Sara F.、Keene Douglas R.、Olbinado Margie、Stampanoni Marco、Kanki Sachiko、Yanagisawa Hiromi、Mosquera Laura Mui?o、Sips Patrick、De Backer Julie、Sakai Lynn Y.
    • Journal Title

      Matrix Biology

      Volume: 123 Pages: 17-33

    • DOI

      10.1016/j.matbio.2023.09.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Journal Article] Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases2023

    • Author(s)
      Dubacher Nicolo、Sugiyama Kaori、Smith Jeffrey D.、Nussbaumer Vanessa、Csonka M?t?、Ferenczi Szilam?r、Kov?cs Krisztina J.、Caspar Sylvan M.、Lamberti Lisa、Meienberg Janine、Yanagisawa Hiromi、Sheppard Mary B.、Matyas Gabor
    • Journal Title

      BioRxiv

      Volume: -

    • DOI

      10.1101/2023.08.15.553452

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Journal Article] Protective Role of Endothelial Fibulin‐4 in Valvulo‐Arterial Integrity2023

    • Author(s)
      Nguyen Tram Anh Vu、Lino Caroline Antunes、Hang Huynh Thuy、Alves Juliano Vilela、Thang Bui Quoc、Shin Seung Jae、Sugiyama Kaori、Matsunaga Hiroko、Takeyama Haruko、Yamashiro Yoshito、Yanagisawa Hiromi
    • Journal Title

      Journal of the American Heart Association

      Volume: 12 Issue: 1

    • DOI

      10.1161/jaha.122.026942

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-23H00431
  • [Journal Article] Experimental and Mouse-Specific Computational Models of the Fbln4SMKO Mouse to Identify Potential Biomarkers for Ascending Thoracic Aortic Aneurysm2022

    • Author(s)
      Bazzi Marisa S.、Balouchzadeh Ramin、Pavey Shawn N.、Quirk James D.、Yanagisawa Hiromi、Vedula Vijay、Wagenseil Jessica E.、Barocas Victor H.
    • Journal Title

      Cardiovascular Engineering and Technology

      Volume: 13 Issue: 4 Pages: 558-572

    • DOI

      10.1007/s13239-021-00600-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-20H03762
  • [Journal Article] Partial endothelial-to-mesenchymal transition mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022

    • Author(s)
      Yamashiro Yoshito、Ramirez Karina、Nagayama Kazuaki、Hattori Naoko、Liu Yu-Yu、Matsunaga Shinji、Tomita Shuhei、Kubota Yoshiaki、Yanagisawa Hiromi
    • Journal Title

      Cardiovascular Research

      Volume: 12 Issue: 7 Pages: 1606-1618

    • DOI

      10.1093/cvr/cvac190

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-20K07072, KAKENHI-PROJECT-23K06365, KAKENHI-PROJECT-22K19890, KAKENHI-PLANNED-23H04929, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21H03804, KAKENHI-PROJECT-23K27352
  • [Journal Article] 大動脈瘤への分子生物学的アプローチ2022

    • Author(s)
      木村健一、柳沢裕美
    • Journal Title

      心臓

      Volume: 54 Pages: 625-734

    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Journal Article] Embracing Diversity, Equity, and Inclusion in the Scientific Community-Viewpoints of the Diversity, Equity, and Inclusion Committee of the North American Vascular Biology Organization2022

    • Author(s)
      Garelnabi Mahdi、Cowdin Mitzy、Fang Yun、Shrestha Bandana、Ushio-Fukai Masuko、Aikawa Elena、Graham Garth、Molema Grietje、Yanagisawa Hiromi、Aikawa Masanori
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 9

    • DOI

      10.3389/fcvm.2022.863256

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Journal Article] TBX1 targets the miR-200?ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties2022

    • Author(s)
      Funato Noriko、Yanagisawa Hiromi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 20188-20188

    • DOI

      10.1038/s41598-022-24604-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09901, KAKENHI-PROJECT-20H03762
  • [Journal Article] The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging2022

    • Author(s)
      Raja Erna、Changarathil Gopakumar、Oinam Lalhaba、Tsunezumi Jun、Ngo Yen Xuan、Ishii Ryutaro、Sasaki Takako、Imanaka‐Yoshida Kyoko、Yanagisawa Hiromi、Sada Aiko
    • Journal Title

      EMBO reports

      Volume: 23 Issue: 12

    • DOI

      10.15252/embr.202255478

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03266, KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-20K22659
  • [Journal Article] The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging2022

    • Author(s)
      Raja Erna、Changarathil Gopakumar、Oinam Lalhaba、Ngo Yen Xuan、Tsunezumi Jun、Ishii Ryutaro、Sasaki Takako、Imanaka-Yoshida Kyoko、Yanagisawa Hiromi、Sada Aiko
    • Journal Title

      bioRxiv

      Volume: N/A

    • DOI

      10.1101/2022.02.28.482241

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03266, KAKENHI-PROJECT-20K22659
  • [Journal Article] Editorial: Extracellular matrix dynamics in biology, bioengineering, and pathology, volume II2022

    • Author(s)
      Loganathan Rajprasad、Yanagisawa Hiromi、Gentleman Eileen、Little Charles D.、Weiss Jeffrey A.
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 10

    • DOI

      10.3389/fcell.2022.1105566

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-20H03762
  • [Journal Article] Fibulin7 aggravates calcium oxalate‐induced acute kidney injury by binding to calcium oxalate crystals2022

    • Author(s)
      Sugiura Hidekazu、Tsunezumi Jun、Yanagisawa Hiromi、Futaya Mayuko、Nitta Kosaku、Tsuchiya Ken
    • Journal Title

      Journal of Cellular Physiology

      Volume: 238 Issue: 1 Pages: 165-178

    • DOI

      10.1002/jcp.30914

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Journal Article] Dysregulated assembly of elastic fibers in fibulin-5 knockout mice results in a tendon-specific increase in elastic modulus2021

    • Author(s)
      Eekhoff Jeremy D.、Steenbock Heiko、Berke Ian M.、Brinckmann Juergen、Yanagisawa Hiromi、Wagenseil Jessica E.、Lake Spencer P.
    • Journal Title

      Journal of the Mechanical Behavior of Biomedical Materials

      Volume: 113 Pages: 104134-104134

    • DOI

      10.1016/j.jmbbm.2020.104134

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Journal Article] Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms2021

    • Author(s)
      Sugiyama Kaori、Marzi Julia、Alber Julia、Brauchle Eva M.、Ando Masahiro、Yamashiro Yoshito、Ramkhelawon Bhama、Schenke-Layland Katja、Yanagisawa Hiromi
    • Journal Title

      Cell Reports Medicine

      Volume: 2 Issue: 5 Pages: 100261-100261

    • DOI

      10.1016/j.xcrm.2021.100261

    • NAID

      120007180697

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-21K15366, KAKENHI-PROJECT-23K21373
  • [Journal Article] Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels2021

    • Author(s)
      Kimura Kenichi、Ramirez Karina、Nguyen Tram Anh Vu、Yamashiro Yoshito、Sada Aiko、Yanagisawa Hiromi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-88126-6

    • NAID

      120007180733

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-23K21373
  • [Journal Article] Isolation and Culture of Primary Oral Keratinocytes from the Adult Mouse Palate2021

    • Author(s)
      Xuan Ngo Yen、Haga Kenta、Suzuki Ayako、Kato Hiroko、Yanagisawa Hiromi、Izumi Kenji、Sada Aiko
    • Journal Title

      Journal of Visualized Experiments

      Volume: 175 Issue: 175

    • DOI

      10.3791/62820

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03266, KAKENHI-PROJECT-20H03762
  • [Journal Article] Extracellular matrix-mediated remodeling and mechanotransduction in large vessels during development and disease2021

    • Author(s)
      Yanagisawa Hiromi、Yokoyama Utako
    • Journal Title

      Cellular Signalling

      Volume: 86 Pages: 110104-110104

    • DOI

      10.1016/j.cellsig.2021.110104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03650, KAKENHI-PROJECT-20H03762, KAKENHI-PROJECT-20K21638
  • [Journal Article] Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging2020

    • Author(s)
      Oinam Lalhaba、Changarathil Gopakumar、Raja Erna、Ngo Yen Xuan、Tateno Hiroaki、Sada Aiko、Yanagisawa Hiromi
    • Journal Title

      Aging Cell

      Volume: 19 Issue: 8

    • DOI

      10.1111/acel.13190

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21431, KAKENHI-PROJECT-20K22659, KAKENHI-PROJECT-20H03762
  • [Journal Article] Role of PAR1-Egr1 in the initiation of Thoracic Aortic Aneurysm in Fibulin-4 deficient mice.2020

    • Author(s)
      Shin SJ, Hang HT, Thang BQ, Shimoda T, Sakamoto H, Osaka M, Hiramatsu Y, Yamashiro Y, Yanagisawa H
    • Journal Title

      Arterioscler. Thromb. Vasc. Biol.

      Volume: 40(8) Issue: 8 Pages: 1905-1917

    • DOI

      10.1161/atvbaha.120.314560

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
  • [Journal Article] The Molecular Mechanism of Mechanotransduction in Vascular Homeostasis and Disease2020

    • Author(s)
      Yamashiro Y, Yanagisawa H
    • Journal Title

      Clin. Sci.

      Volume: 134(17) Issue: 17 Pages: 2399-2418

    • DOI

      10.1042/cs20190488

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
  • [Journal Article] Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium2020

    • Author(s)
      Ishii Ryutaro、Yanagisawa Hiromi、Sada Aiko
    • Journal Title

      Development

      Volume: 147 Issue: 24

    • DOI

      10.1242/dev.197590

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03266, KAKENHI-PROJECT-20H03762
  • [Journal Article] 血管におけるマトリクスエイジング2020

    • Author(s)
      中邨智之、 柳沢裕美
    • Journal Title

      バイオマテリアル

      Volume: 38(3) Pages: 172-177

    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Journal Article] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling2020

    • Author(s)
      Yamashiro Yoshito、Thang Bui Quoc、Ramirez Karina、Shin Seung Jae、Kohata Tomohiro、Ohata Shigeaki、Nguyen Tram Anh Vu、Ohtsuki Sumio、Nagayama Kazuaki、Yanagisawa Hiromi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 18 Pages: 9896-9905

    • DOI

      10.1073/pnas.1919702117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22944, KAKENHI-PROJECT-17H02077, KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-20H03762
  • [Journal Article] Elastic fibers and biomechanics of the aorta: Insights from mouse studies.2019

    • Author(s)
      Yanagisawa H, Wagenseil J
    • Journal Title

      Matrix Biology

      Volume: 印刷中 Pages: 160-172

    • DOI

      10.1016/j.matbio.2019.03.001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Fibulin-4 exerts a dual role in LTBP-4L?mediated matrix assembly and function2019

    • Author(s)
      Kumra Heena、Nelea Valentin、Hakami Hana、Pagliuzza Amelie、Djokic Jelena、Xu Jiongci、Yanagisawa Hiromi、Reinhardt Dieter P.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 41 Pages: 20428-20437

    • DOI

      10.1073/pnas.1901048116

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] 大動脈瘤形成に関与するメカノトランスダクション機構2019

    • Author(s)
      山城義人、柳沢裕美
    • Journal Title

      医学のあゆみ

      Volume: 269 Pages: 552-553

    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Novel ELN mutation in a Japanese family with a severe form of supravalvular aortic stenosis2019

    • Author(s)
      Sugiyama K, Horigome H, Lin L, Murakami T, Shiono J, Yamashiro Y, Matsuura H, Yoda H, Yanagisawa H
    • Journal Title

      Molecular Genetics & Genomic Medicine

      Volume: 7 Issue: 11

    • DOI

      10.1002/mgg3.986

    • NAID

      120007133081

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07813, KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-17H04289
  • [Journal Article] Recent updates on the molecular network of elastic fiber formation2019

    • Author(s)
      Shin Seung Jae、Yanagisawa Hiromi
    • Journal Title

      Essays in Biochemistry

      Volume: 63 Issue: 3 Pages: 365-376

    • DOI

      10.1042/ebc20180052

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] A Case of Noonan Syndrome with the <i>SHOC2</i> Mutation Complicated by Dilation of a Single Left Coronary Artery2019

    • Author(s)
      Ishikawa N, Horigome H, Murakami T, Takahashi-Igari M, Nozaki Y, Lin L, Shiono J, Hiramatsu Y, Yanagisawa H
    • Journal Title

      Pediatric Cardiology and Cardiac Surgery

      Volume: 35 Issue: 2 Pages: 127-131

    • DOI

      10.9794/jspccs.35.127

    • NAID

      130007726216

    • ISSN
      0911-1794, 2187-2988
    • Year and Date
      2019-05-01
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07813, KAKENHI-PROJECT-19K19820, KAKENHI-PROJECT-17H04289
  • [Journal Article] Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.2019

    • Author(s)
      J. Burger, N. van Vliet, P. van Heijningen, H. Kumra, G. J. Kremers, M. Alves, G. van Cappellen, H. Yanagisawa, D. P. Reinhardt, R. Kanaar, I. van der Pluijm, J. Essers
    • Journal Title

      Cell Signaling

      Volume: 58 Pages: 65-78

    • DOI

      10.1016/j.cellsig.2019.02.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Role of thrombospondin-1 in mechanotransduction and development of thoracic aortic aneurysm in mouse and humans.2018

    • Author(s)
      Yamashiro Y, Thang BQ, Shin SJ, Lino CA, Nakamura T, Kim J, Sugiyama K, Tokunaga C, Sakamoto H, Osaka M, Davis EC, Wagenseil JE, Hiramatsu Y and Yanagisawa H.
    • Journal Title

      Circulation Research

      Volume: 123(6) Issue: 6 Pages: 660-672

    • DOI

      10.1161/circresaha.118.313105

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-16H05145, KAKENHI-PROJECT-17H04289, KAKENHI-PROJECT-17K19534
  • [Journal Article] Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.2018

    • Author(s)
      Tsunezumi J, Sugiura H, Oinam L, Ali A, Thang BQ, Sada A, Yamashiro Y, Kuro-O M and Yanagisawa H.
    • Journal Title

      Matrix Biology

      Volume: 74 Pages: 5-20

    • DOI

      10.1016/j.matbio.2018.04.014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15057, KAKENHI-PROJECT-17H04289
  • [Journal Article] Crossing Bridges between Extra- and Intra-Cellular Events in Thoracic Aortic Aneurysms2018

    • Author(s)
      Yamashiro Y, Yanagisawa H.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 25 Issue: 2 Pages: 99-110

    • DOI

      10.5551/jat.RV17015

    • NAID

      130006328449

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.2018

    • Author(s)
      I. van der Pluijm, J. Burger, (24名中21), H. Yanagisawa, H. Dietz, R. Kanaar, and J. Essers
    • Journal Title

      Cardiovascular Research

      Volume: 114(13) Issue: 13 Pages: 1776-1793

    • DOI

      10.1093/cvr/cvy150

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1.2017

    • Author(s)
      Kim CW, Pokutta-Paskaleva A, Kumar S, Timmins LH, Morris AD, Kang DW, Dalal S, Chadid T, Kuo KM, Raykin J, Li H, Yanagisawa H, Gleason RL Jr, Jo H, Brewster LP.
    • Journal Title

      Circulation

      Volume: 136(13) Issue: 13 Pages: 1217-1232

    • DOI

      10.1161/circulationaha.116.026361

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Crosslinked elastic fibers are necessary for low energy loss in the ascending aorta.2017

    • Author(s)
      Kim J, Staiculescu MC, Cocciolone AJ, Yanagisawa H, Mecham RP, Wagenseil JE.
    • Journal Title

      J Biomech

      Volume: 61 Pages: 199-207

    • DOI

      10.1016/j.jbiomech.2017.07.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] Comparison of 10 murine models reveals a distinct biomechanical phenotype in thoracic aortic aneurysms.2017

    • Author(s)
      C. Bellini, M. R. Bersi, A. W. Caulk, J. Ferruzzi, D. M. Milewicz, F. Ramirez, D. B. Rifkin, G. Tellides, H. Yanagisawa, J. D. Humphrey
    • Journal Title

      J R Soc Interface

      Volume: 130 Issue: 130 Pages: 20161036-20161036

    • DOI

      10.1098/rsif.2016.1036

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Journal Article] MMP17/MT4-MMP and thoracic aortic aneurysms: OPNing new potential for effective treatment2015

    • Author(s)
      C. L. Papke, Y. Yamashiro, and H. Yanagisawa
    • Journal Title

      Circulation Research

      Volume: 117 Pages: 109-112

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20898
  • [Journal Article] Abnormal mechanosensing and cofilin activation promotes the progression of ascending aortic aneurysms in mice2015

    • Author(s)
      Y. Yamashiro, C. L. Papke, J. Kim, L.-J. Ringuette, Q.-J. Zhang, Z.-P. Liu, H. Mirzaei, J. E. Wagenseil, E. C. Davis, and H. Yanagisawa
    • Journal Title

      Science Signaling

      Volume: 8(399) Issue: 399

    • DOI

      10.1126/scisignal.aab3141

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20898
  • [Journal Article] Loss of fibulin-4 disrupts collagen synthesis and maturation: Implications for pathology resulting from EFEMP2 mutations2015

    • Author(s)
      C. L. Papke, J. Tsunezumi, L.-J. Ringuette, H. Nagaoka, M. Terajima, Y. Yamashiro, G. Urquhart, M. Yamauchi, E. C. Davis, and H. Yanagisawa
    • Journal Title

      Human Molecular Genetics

      Volume: 15;24(20) Issue: 20 Pages: 5867-79

    • DOI

      10.1093/hmg/ddv308

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20898
  • [Presentation] Spatio-temporal analysis of cell populations in dissecting aortic wall2024

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      日本循環器学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Abnormal mechanotransduction and its implication in aortic disease2024

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      RIKEN IDWGIS Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Abnormal mechanotransduction and its implication in aortic disease2024

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      RIKEN IDWGIS Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] Spatio-temporal analysis of cell populations in dissecting aortic wall2024

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      日本循環器学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] 解離大動脈壁に出現する細胞集団の 時空間解析と病態解明2023

    • Author(s)
      柳沢裕美
    • Organizer
      心血管代謝週間
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] 解離大動脈壁に出現する細胞集団の 時空間解析と病態解明2023

    • Author(s)
      柳沢裕美
    • Organizer
      心血管代謝週間
    • Invited
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] A Novel Mouse Model of Aortic Dissection Caused by a Point Mutation in the Hybrid Domain of the Fibrillin-1 Gene2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Gordon Research Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] A Novel Mouse Model of Aortic Dissection Caused by a Point Mutation in the Hybrid Domain of the Fibrillin-1 Gene2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Gordon Research Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] Cell-matrix interactions in the maintenance of vascular wall2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Korean Society for Biochemistry and Molecular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] The expanding roles of short fibulins: elastogenesis and beyond2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Gordon Resarch Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] The expanding roles of short fibulins: elastogenesis and beyond2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Gordon Resarch Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Cell-matrix interactions in the maintenance of vascular wall2023

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Korean Society for Biochemistry and Molecular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] 細胞外マトリクスと血管壁の維持機構2023

    • Author(s)
      柳沢 裕美
    • Organizer
      CVEM オンラインセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] 細胞外マトリクスと血管壁の維持機構2023

    • Author(s)
      柳沢 裕美
    • Organizer
      CVEM オンラインセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] 血管と血管外細胞の相互作用から読み解く 大動脈解離の発症機序2023

    • Author(s)
      柳沢裕美
    • Organizer
      日本分子生物学会年会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Investigation of the molecular mechanism of BAV-associated aortopathy2023

    • Author(s)
      Chang Liu, Chiho Tokunaga, Kaori Sugiyama, Kenichi Kimura, Toru Tsukda1, Hideyuki Kato1, Muneaki Matsubara1, Motoo Osaka1, Hiroaki Sakamoto1, Hiroko Matsunaga, Haruko Takeyama, Hiromi Yanagisawa,Yuji Hiramatsu
    • Organizer
      第76回日本胸部外科学会定期学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K08247
  • [Presentation] 細胞外環境の破綻による血管障害のメカニズム2022

    • Author(s)
      柳沢 裕美
    • Organizer
      日本心脈管作動物質学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Matrix-cell interactions and aortic diseases2022

    • Author(s)
      Yanagisawa Hiromi
    • Organizer
      International Vascular Biology Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] ラベルフリーイメージングによるマルファン症候群モデルマウスを用いた急性大動脈解離シグナル探索2022

    • Author(s)
      杉山 夏緒里、安藤 正浩、松永 浩子、柳沢 裕美、竹山春子
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] マルファン症候群モデルマウスを用いた大動脈解離発症メカニズムの解明2022

    • Author(s)
      木村健一、本山絵理、石井柳太郎、杉山夏緒里、山城義人、神吉佐智子、柳沢裕美
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Identification of collagen-derived biomolecular fingerprints specific for thoracic aortic aneurysms by Raman microspectroscopy and imaging2022

    • Author(s)
      Kaori Sugiyama, Julia Marzi, Masahiro Ando, Bhama Ramkhelawon, Katja Schenke-Layland, Hiromi Yanagisawa, Haruko Takeyama
    • Organizer
      日本生物工学会若手の会
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Investigating the molecular mechanism of stiff skin-like phenotype in a mouse model caused by a new point mutation in the hybrid domain 1 of fibrillin 1 gene2022

    • Author(s)
      Hossain ASM Sakhawat, Erna Raja, Eri Motoyama, Kenichi Kimura, Hiromi Yanagisawa
    • Organizer
      TGSW (Tsukuba Global Science Week 2022)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] A novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene2022

    • Author(s)
      Kenichi Kimura, Eri Motoyama, Ryutaro Ishii, Kaori Sugiyama, Yoshito Yamashiro, Violette Deleeuw, Patrick Sips, Julie De Backer, Laura Muino-Mosquera, Lynn Y. Sakai, Sachiko Kanki, Hiromi Yanagisawa
    • Organizer
      11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] マルファン症候群モデルマウスを用いた大動脈解離発症メカニズムの解明2022

    • Author(s)
      木村健一、本山絵理、石井柳太郎、杉山夏緒里、山城義人、神吉佐智子、柳沢裕美
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Matrix-cell Interactions and Aortic Aneurysms2022

    • Author(s)
      Yanagisawa Hiromi
    • Organizer
      European Circulation Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Partial endothelial-to-mesenchymal transition (EndMT) mediated by HIF-induced CD45 in neointima formation upon carotid artery ligation2022

    • Author(s)
      Yoshito Yamashiro, Karina Ramirez, Kazuaki Nagayama, Naoko Hattori, Yu-Yu Liu, Shinji Matsunaga, Shuhei Tomita, Yoshiaki Kubota and Hiromi Yanagisawa
    • Organizer
      International Vascular Biology Meeting 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] マルファン症候群モデルマウスを用いた急性大動脈解離シグナル探索とラベルフリーイメージング作製2022

    • Author(s)
      杉山夏緒里、安藤正浩、我妻竜太、松永浩子、柳沢裕美、竹山春子
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Matrix-cell interactions and aortic diseases2022

    • Author(s)
      Yanagisawa Hiromi
    • Organizer
      International Vascular Biology Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Matrix-cell Interactions and Aortic Aneurysms2022

    • Author(s)
      Yanagisawa Hiromi
    • Organizer
      European Circulation Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] A novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene2022

    • Author(s)
      Kenichi Kimura, Eri Motoyama, Ryutaro Ishii, Kaori Sugiyama, Yoshito Yamashiro, Violette Deleeuw, Patrick Sips, Julie De Backer, Laura Muino-Mosquera, Lynn Y. Sakai, Sachiko Kanki, Hiromi Yanagisawa
    • Organizer
      11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] ラベルフリーイメージングによるマルファン症候群モデルマウスを用いた急性大動脈解離シグナル探索2022

    • Author(s)
      杉山夏緒里、安藤正浩、松永浩子、柳沢裕美、竹山春子
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] A Novel mouse model of aortic dissection caused by a point mutation in the hybrid domain of the fibrillin-1 gene2022

    • Author(s)
      Kenichi Kimura, Eri Motoyama, Ryutaro Ishii, Kaori Sugiyama, Yoshito Yamashiro, Violette Deleeuw, Patrick Sips, Julie De Backer, Laura Muino Mosquera, Lynn Y Sakai, Sachiko Kanki, Tomoyuki Nakamura, Hiromi Yanagisawa
    • Organizer
      The 6th JCS Counsil Forum on Basic Cardiovascular Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Label-free imaging for acute aortic dissection by using Marfan syndrome model mouse2022

    • Author(s)
      Kaori Sugiyama, Masahiro Ando, Ryota Wagatsuma, Hiromi Mataunaga, Francesco Ramirez, Katja Schenke-Layland, Hiromi Yanagisawa, Haruko Takeyama
    • Organizer
      11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Protective role of endothelial fibulin-4 in valvulo-arterial integrity2022

    • Author(s)
      Nguyen Vu Tram Anh, Caroline Antunes Lino, Hang Huynh, Juliano Vilela Alves, Bui Quoc Thang, Shin SeunJse, Kaori Sugiyama, Hiroko Matsunaga, Haruko Takeyama, Yoshito Yamashiro and Hiromi Yanagisawa
    • Organizer
      International Vascular Biology Meeting 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] 細胞外マトリクスと血管壁の維持機構2022

    • Author(s)
      柳沢 裕美
    • Organizer
      日本心臓血管発生研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Label-free imaging for acute aortic dissection by using Marfan syndrome model mouse2022

    • Author(s)
      Kaori Sugiyama, Masahiro Ando, Ryota Wagatsuma, Hiromi Mataunaga, Francesco Ramirez, Katja Schenke-Layland, Hiromi Yanagisawa, Haruko Takeyama
    • Organizer
      11th International Symposium on Marfan, Loeys-Dietz, and Related Conditions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] 細胞外マトリクスと血管壁の維持機構2022

    • Author(s)
      柳沢 裕美
    • Organizer
      日本心臓血管発生研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] マルファン症候群モデルマウスを用いた急性大動脈解離シグナル探索とラベルフリーイメージング作製2022

    • Author(s)
      杉山夏緒里、安藤正浩、我妻竜太、松永浩子、柳沢裕美、竹山春子
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] マトリクスによるメカノトランスダクション制御機構と 大動脈疾患2021

    • Author(s)
      柳沢裕美
    • Organizer
      日本血管生物医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Matrix-cell Interactions and aortic diseases2021

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      North American Vascular Organization
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Searching for novel biomarkers of thoracic aortic aneurysms using Raman microspectroscopy2021

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      The international Society for Applied Cardiovascular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Matrix-mediated mechanotransduction In the aortic wall2021

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      3M conference (Materials, Mimics, and Microfluidics:Engineering Tools for Mechanobiology)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] ラマン分光法を用いた大動脈瘤の新規イメージングと スペクトル解析2021

    • Author(s)
      柳沢裕美
    • Organizer
      日本動脈硬化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] 細胞外マトリックスに着目した 大動脈瘤のラマン分光イメージング法2021

    • Author(s)
      柳沢裕美
    • Organizer
      日本血管生物医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] 新規Fbn1遺伝子変異マウスを用いたマルファン症候群の大動脈解離発症機序の解明2021

    • Author(s)
      本山絵理、木村健一、石井柳太郎、杉山夏緒里、山城義人、神吉佐智子、柳沢裕美
    • Organizer
      エラスチン・関連分子研究会学術集会
    • Data Source
      KAKENHI-PROJECT-21KK0151
  • [Presentation] Raman Microspectroscopy and Imaging Reveal Novel Biomarkers Specific for Thoracic Aortic Aneurysm2020

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      GenTAC Aortic Summit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Matrix-mediated mechanotransduction and aortic aneurysms2020

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      North American Vascular Biology Organization
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03762
  • [Presentation] Role of PAR1-Egr1 in the initiation of thoracic aortic aneurysm2019

    • Author(s)
      Seung Jae Shin, Yoshito Yamashiro, Thang Bui Quoc, Yuji Hiramatsu, Hiromi Yanagisawa
    • Organizer
      日本循環器学会基礎研究フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] 血管壁のメカノトランスダクションと弾性線維2019

    • Author(s)
      柳沢裕美
    • Organizer
      エラスチン・関連分子研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Dual role of thrombospondin-1 in aortic remodeling and disease2019

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      FASEB Science Research Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP signaling pathway in remodeling of vessel wall2019

    • Author(s)
      Yoshito Yamashiro, Bui Quoc Thang, Karina Ramirez, Seung Jae Shin, Tomohiro Kohata, Shigeaki Ohata, Tram Anh Vu Nguyen, Sumio Ohtsuki, Kazuaki Nagayama, and Hiromi Yanagisawa
    • Organizer
      GRC on Fibronectin, integrins and related molecules
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Cell-specific function of fibulin-4 in progression of ascending aortic aneurysm in mice2019

    • Author(s)
      Nguyen Vu Tram Anh1, Huynh Thuy Hang, Caroline Antunes Lino, Bui Quoc Thang, Juliano Vilela Alves, Yoshito Yamashiro1 and Hiromi Yanagisawa
    • Organizer
      日本循環器学会基礎研究フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Label-free Raman imaging for non-invasive diagnostic tools of thoracic aortic aneurysm2019

    • Author(s)
      Kaori Sugiyama, Julia Marzi, Eva Brauchle, Masahiro Ando, Yoshito Yamashiro, Katja Schenke-Layland, Hiromi Yanagisawa
    • Organizer
      GRC on Elastin, Elastic fibers, and Microfibrils
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] ラマン分光法と多変量解析を用いた胸部大動脈瘤に特異的な生体分子指紋の同定2019

    • Author(s)
      Kaori Sugiyama, Julia Marzi, Eva Brauchle, Masahiro Ando, Yoshito Yamashiro, Katja Schenke-Layland, Hiromi Yanagisawa
    • Organizer
      エラスチン・関連分子研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Role of PAR1-Egr1 in the initiation of thoracic aortic aneurysm2019

    • Author(s)
      Seung Jae Shin, Yoshito Yamashiro, Thang Bui Quoc, Yuji Hiramatsu, Hiromi Yanagisawa
    • Organizer
      NAVBO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Contribution of PDGFRα-positive cell populations during vascular remodeling2019

    • Author(s)
      Karina Ramirez, Nguyen Vu Tram Anh, Yoshito Yamashiro, Aiko Sada, Hiromi Yanagisawa
    • Organizer
      日本循環器学会基礎研究フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] メカニカスストレス応答破綻による 大動脈瘤形成とトロンボスポンディンの役割2019

    • Author(s)
      柳沢裕美
    • Organizer
      日本心脈管作動物質学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] 家族性大動脈弁上狭窄症における新規エラスチン遺伝子変異の同定と解析2019

    • Author(s)
      杉山 夏緒里, 堀米 仁志, 村上 卓,林 立申, 野崎 良寛, 塩野 淳子, 松裏 裕行, 緒方 公平, 柳沢 裕美
    • Organizer
      日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Role of PAR1-Egr1 in the initiation of thoracic aortic aneurysm2019

    • Author(s)
      辛 承宰,ヒョン スイ ハン,山城 義人,タン ブイ クゥオ,平松 祐司,柳沢 裕美
    • Organizer
      日本血管生物医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] マトリクスメカノトランダクションと血管リモデリング2019

    • Author(s)
      Yoshito Yamashiro, Thang Bui Quoc,Ramirez Karina,Shin Seung Jae,Tomohiro Kohata,Shigeaki Ohata, Nguyen Tram Anh Vu,Sumio Ohtsuki, Kazuaki Nagayama,Hiromi Yanagisawa
    • Organizer
      日本血管生物医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Roles of Mechanotransduction and Thrombospondin-1 in Development of Thoracic Aortic Aneurysm2019

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Japanese Circulation Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] 平滑筋メカノトランスダクションにおけるThrombospondin-1 の役割2019

    • Author(s)
      柳沢裕美
    • Organizer
      MatriCell フォーラム
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Short Fibulins in Development and Disease2019

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Japanese Society of Podocyte Biology
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP signaling pathway in remodeling ofvessel wall2019

    • Author(s)
      Yoshito Yamashiro, Hiromi Yanagisawa
    • Organizer
      NAVBO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Contribution of matrix mechanotransduction in vascular remodeling2019

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      Gordon Research Conference on Elastin, Elastic fibers and Microfibrils
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] ラマン分光法と多変量解析を用いた胸部大動脈瘤に特異的な生体分子指紋の同定2019

    • Author(s)
      杉山夏緒里 , Julia Marzi, Eva Brauchle, 安藤正浩、山城義人, Katja Schenke-Layland, 柳沢裕美
    • Organizer
      日本分光学会生細胞分光部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Fibulin-7は腎尿細管石灰化に関与するヘパリン結合性マトリセルラータンパク質である2018

    • Author(s)
      柳沢裕美
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Role of Short Fibulins in Maintenance of Vessel Walls2018

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      American Society for Matrix Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] 腎・血管における短鎖 Fibulins の役割2018

    • Author(s)
      柳沢裕美
    • Organizer
      日本生化学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] The role of thrombospoindin-1 in ascending aortic aneurysms in fibulin-4 mutant mice2017

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      North American Vascular Biology Organization
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Comparison of Signaling Pathways involved in Aortic Aneurysms Using Fibulin-4 and Fibulin-5 Mutant Mice2017

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      第81回日本循環器病学会
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] メカニカルストレスによる心血管リモデリングと 細胞外マトリックス2017

    • Author(s)
      柳沢裕美
    • Organizer
      心筋生検研究会ジョイントセッション 第81回日本循環器学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
  • [Presentation] Recent Progress in Short Fibulin Family2017

    • Author(s)
      Hiromi Yanagisawa
    • Organizer
      日本結合組織学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04289
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