Chamoto Kenji 茶本健司

… Alternative Names

CHAMOTO Kenji 茶本健司

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Researcher Number	50447041
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 医学研究科, 特定教授 2017 – 2023: 京都大学, 医学研究科, 特定准教授 2016: 京都大学, 医学研究科, 特定講師 2015: 京都大学, 医学(系)研究科(研究院), 講師 2012: 北海道大学, 遺伝子病制御研究所, 助教 2008: Hokkaido University, 遺伝子病研究所, 助教 2007 – 2008: Hokkaido University, 遺伝子病制御研究所, 助教
Review Section/Research Field	Principal Investigator Immunology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 56050:Otorhinolaryngology-related / Tumor therapeutics / Tumor biology and related fields Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 52040:Radiological sciences-related / Radiation science
Keywords	Principal Investigator PD-1 / がん免疫 / 免疫学 / 腫瘍免疫 / 癌 / 細胞性免疫 / 体液性免疫 / 腫瘍免疫学 / ネオ抗原 / ファージディスプレイ … More / 自己免疫 / 疲弊T細胞 / 免疫チェックポイント阻害剤 / 生体分子 / Foxp3 / ヘルパーT細胞 / B 細胞 / Treg / キラーT細胞 / IgA / IFN / 腸内細菌 / B細胞 / 遺伝子 / バイオマーカー / 免疫抑制 / 抗腫瘍免疫 / 免疫逃避機構 / CRISPR / 細胞生物学 / サイトカイン … More Except Principal Investigator 婦人科がん / 腫瘍免疫 / 子宮体癌 / 卵巣癌 / 婦人科腫瘍学 / TLS / PD-1 / 免疫ゲノミクス / 多様性 / 細菌叢 / 3次リンパ様構造 / B細胞性免疫 / T細胞 / B細胞 / 婦人科癌 / リアルタイム適合照射 / 免疫賦活 / PD-L1阻害 / ヘリウム / 4次元分割照射 / 免疫放射線治療 / 陽子線CT / ヘリウム線治療 / PD-1機能 / 低LET / 免疫賦活照射 / ヘリウム線 / 陽子線 / PD-L1 / 免疫ダイナミクス / 免疫チェックポイント / 免疫ダイナミズム / 婦人科腫瘍 / プラスチック検出器 / 非線形最適化 / 体幹部定位放射線照射 / プラスチック檢出器 / モンテカルロ法 / 電子線トラック解析 / 量子線シミュレーション / 低酸素細胞 / 胃癌 / 細胞遊走 / 生体の動き / 医学研究 / 動体追跡 / 放射線治療 Less

Elucidation of tertiary lymphoid structures (TLS) in gynecological cancer and basic investigation of new treatment development
- Principal Investigator
  
  濱西潤三
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
Identification of neoantigens promoting inflammagingPrincipal Investigator
- Principal Investigator
  
  茶本健司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
Impact of circulating exhausted T cells with different stages on PD-1 blockade caner immunotherapyPrincipal Investigator
- Principal Investigator
  
  Chamoto Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kyoto University
Investigation of B-cell immunity against gynecological cancer and new strategies for diagnosis and treatment
- Principal Investigator
  
  濱西潤三
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
Novel diagnostic and therapeutic strategies for ovarian cancer by investigation of cancer and host diversity
- Principal Investigator
  
  万代昌紀
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
Research and development about helium and proton hybrid system with proton CT and Immuno-radiotherapy
- Principal Investigator
  
  白土博樹
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Investigation of immune-suppressive dynamism and exploratory research for new treatment strategy for gynecologic cancer
- Principal Investigator
  
  Hamanishi Junzo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
Identification of PD-1 blocked responsive genes and functional analysis based on tumor eradication system in vivo.Principal Investigator
- Principal Investigator
  
  Chamoto Kenji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Kyoto University
Elucidation of anti-tumor immune mechanism including Treg inhibition by PD-1 blockade.Principal Investigator
- Principal Investigator
  
  Chamoto Kenji
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyoto University
抗PD-1抗体による抗腫瘍免疫応答の解明Principal Investigator
- Principal Investigator
  
  茶本健司
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Research for Real-time Tracking Medical Science
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
The development of type-1 tumor immunotherapy based on removing immunosupression from tumor-bearerPrincipal Investigator
- Principal Investigator
  
  CHAMOTO Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University

All 2020 2019 2018 2017 2016 2015 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

[Book] Bio Clinica 352020
- Author(s)
  平野智子，茶本健司
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] がん免疫成立の基盤となるCancer-Immunity Cycle　第４回　ステップ７～１2020
- Author(s)
  仲島由佳、茶本健司、河上　裕
- Total Pages
  1
- Publisher
  Trends in Cancer Immunology in press
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 生体の科学 702020
- Author(s)
  高塚奈津子、茶本健司
- Publisher
  金原一郎記念医学医療振興財団
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 癌と化学療法 472020
- Author(s)
  嶋崎元宣、茶本健司
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 医学のあゆみ 2712019
- Author(s)
  波多江龍亮、茶本健司
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] メディカル・サイエンス・ダイジェスト 45(2),95-98. 祝　本庶佑ノーベル賞受賞記念特集号　がん免疫治療の新展開：免疫代謝とPD－１阻害剤2019
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] メディカル・サイエンス・ダイジェスト 45(2),95-98. 祝　本庶佑ノーベル賞受賞記念特集号　がん免疫治療の新展開：免疫代謝とPD－１阻害剤2019
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] The Lipid 第134号　特集：免疫と代謝の接点：イムノメタボリズム, 30(2),195-202. イムノメタボリズムの新たな展開：がんとイムノメタボリズム2019
- Author(s)
  高塚奈津子、茶本健司
- Total Pages
  8
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 生体の科学 70（３）　特集：免疫チェックポイントによる免疫制御, in press. PD-1/PD-L1による免疫制御2019
- Author(s)
  高塚奈津子、茶本健司
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] 生体の科学 70（３）　特集：免疫チェックポイントによる免疫制御, in press. PD-1/PD-L1による免疫制御2019
- Author(s)
  高塚奈津子、茶本健司
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] The Lipid 第134号2019
- Author(s)
  高塚奈津子、茶本健司
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] The Lipid 第134号　特集：免疫と代謝の接点：イムノメタボリズム, 30(2),195-202. イムノメタボリズムの新たな展開：がんとイムノメタボリズム2019
- Author(s)
  高塚奈津子、茶本健司
- Total Pages
  8
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] がん分子標的治療 16 (2),90-93. PD-1阻害がん免疫療法におけるミトコンドリアを介したエネルギー代謝の重要性」2018
- Author(s)
  仲島由佳、茶本健司
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] JSI Newsletter 26 (2), 8. T細胞のエネルギー代謝とがん免疫2018
- Author(s)
  茶本健司
- Publisher
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] がん分子標的治療 16(3),243-248. がん免疫治療の効果増強法の開発：併用治療の現状と展望2018
- Author(s)
  熱田雄、波多江龍亮、茶本健司
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] 現代化学 (573),28-32. PD-1阻害による新たながん治療法の開発2018
- Author(s)
  伊藤寿宏、茶本健司
- Total Pages
  5
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] 臨床免疫・アレルギー科 69 (6), 546-551. 免疫代謝制御とPD-1阻害がん免疫治療2018
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] がん分子標的治療 16 (2),90-93. PD-1阻害がん免疫療法におけるミトコンドリアを介したエネルギー代謝の重要性」2018
- Author(s)
  仲島由佳、茶本健司
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] 「免疫と炎症」27(1),7-13. T細胞代謝のリプログラミングと抗腫瘍免疫2018
- Author(s)
  伊藤寿宏、茶本健司
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 実験医学 36 (9), 1468-1473. がん局所の代謝改善による免疫抑制の解除2018
- Author(s)
  高塚奈津子、茶本健司
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] Vita 35 (1), 49-57. 企画：特集がん免疫療法の展開、総論：抗PD-1抗体を用いたがん免疫治療の現状と進展2018
- Author(s)
  茶本健司
- Total Pages
  9
- Publisher
  ビー・エム・エル
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 日経サイエンス12月号監修者ノート 48(12),12-19. 免疫の「ブレーキ」解除でがんをたたく2018
- Author(s)
  茶本健司
- Total Pages
  8
- Publisher
  日経サイエンス社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] Vita 35 (1), 49-57. 企画：特集がん免疫療法の展開、総論：抗PD-1抗体を用いたがん免疫治療の現状と進展2018
- Author(s)
  茶本健司
- Total Pages
  9
- Publisher
  ビー・エム・エル
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] Vita2018
- Author(s)
  茶本健司
- Total Pages
  7
- Publisher
  ビー・エム・エル
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 臨床免疫・アレルギー科 69 (6), 546-551. 免疫代謝制御とPD-1阻害がん免疫治療2018
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] コスモバイオニュース「がん免疫」. がん免疫治療の現状と展望2018
- Author(s)
  茶本健司
- Publisher
  コスモバイオ株式会社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] 「免疫と炎症」27(1),7-13. T細胞代謝のリプログラミングと抗腫瘍免疫2018
- Author(s)
  伊藤寿宏、茶本健司
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] JSI Newsletter 26 (2), 8. T細胞のエネルギー代謝とがん免疫2018
- Author(s)
  茶本健司
- Publisher
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K19593
[Book] がん分子標的治療 16(3),243-248. がん免疫治療の効果増強法の開発：併用治療の現状と展望2018
- Author(s)
  熱田雄、波多江龍亮、茶本健司
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 日経サイエンス12月号監修者ノート 48(12),12-19. 免疫の「ブレーキ」解除でがんをたたく2018
- Author(s)
  茶本健司
- Total Pages
  8
- Publisher
  日経サイエンス社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] コスモバイオニュース「がん免疫」. がん免疫治療の現状と展望2018
- Author(s)
  茶本健司
- Publisher
  コスモバイオ株式会社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 現代化学 (573),28-32. PD-1阻害による新たながん治療法の開発2018
- Author(s)
  伊藤寿宏、茶本健司
- Total Pages
  5
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 実験医学 36 (9), 1468-1473. がん局所の代謝改善による免疫抑制の解除2018
- Author(s)
  高塚奈津子、茶本健司
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 実験医学2017
- Author(s)
  高塚奈津子、茶本健司
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 血液フロンティア2017
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  6
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] The Lung perspective2017
- Author(s)
  仲島由佳、波多江龍亮、茶本健司
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] ミトコンドリアを介した抗腫瘍免疫の制御2016
- Author(s)
  茶本健司
- Total Pages
  3
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] Programmed cell death -1（PD-1）を標的とした免疫チェックポイント阻害療法2016
- Author(s)
  波多江龍亮、茶本健司
- Total Pages
  8
- Publisher
  臨床血液
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] 免疫チェックポイント阻害薬の効果と毒性2016
- Author(s)
  茶本健司
- Total Pages
  5
- Publisher
  がん分子標的治療
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] PD-1によるがん免疫逃避機構2016
- Author(s)
  茶本健司、仲島由佳
- Total Pages
  5
- Publisher
  Bio Clinica
- Data Source
  KAKENHI-PROJECT-16H06149
[Book] がん分子標的治療2015
- Author(s)
  茶本健司
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15H06331
[Book] 細胞工学2008
- Author(s)
  茶本健司、脇田大功、西村孝司
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-19790351
[Book] 免疫バランス制御の新しいパラダイム : Th1主導免疫によるがんエスケープ機構の克服2008
- Author(s)
  茶本健司、脇田大功、西村孝司
- Total Pages
  7
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy2020
- Author(s)
  Hatae R, Chamoto K, Kim YH, Sonomura K, Taneishi K, Kawaguchi S, Yoshida H, Ozasa H, Sakamori Y, Akrami M, Fagarasan S, Masuda I, Okuno Y, Matsuda F, Hirai T, Honjo T.
- Journal Title
  
  JCI insight
  
  Volume: 5 Issue: 2 Pages: 133501-133501
- DOI
  10.1172/jci.insight.133501
- NAID
  120006784459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06149, KAKENHI-PROJECT-19K17673
[Journal Article] Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy2020
- Author(s)
  Kumar A, Chamoto K, Chowdhury PS, Honjo T
- Journal Title
  
  eLife
  
  Volume: 9 Pages: 1-21
- DOI
  10.7554/elife.52330
- NAID
  120006936324
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18J15051, KAKENHI-PROJECT-16H06149
[Journal Article] Current issues and perspectives in PD-1 blockade cancer immunotherapy2019
- Author(s)
  Chamoto K, Hatae R, Honjo T
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: in press Issue: 5 Pages: 790-800
- DOI
  10.1007/s10147-019-01588-7
- NAID
  120006850280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06149, KAKENHI-PROJECT-19K17673
[Journal Article] Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma.2019
- Author(s)
  Goto M, Chamoto K, Higuchi K, Yamashita S, Noda K, Iino T, Miura M, Yamasaki T, Ogawa O, Sonobe M, Date H, Hamanishi J, Mandai M, Tanaka Y, Chikuma S, Hatae R, Muto M, Minamiguchi S, Minato N, Honjo T
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10144-10144
- DOI
  10.1038/s41598-019-46548-3
- NAID
  120006724630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05431, KAKENHI-PROJECT-18H02945, KAKENHI-PROJECT-17K19591, KAKENHI-PROJECT-16H06149
[Journal Article] PPAR-induced fatty acid oxidation in T cells increases the number of tumor-reactive CD8+ T cells and facilitates anti*****PD-1 therapy.2018
- Author(s)
  Chowdhury PS*, Chamoto K* (*equally contributed), Kumar A, Honjo T.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 6 Pages: 1375-1387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06149
[Journal Article] VISTA expressed in tumour cells regulates T cell function2018
- Author(s)
  Mulati Kumuluzi、Hamanishi Junzo、Matsumura Noriomi、Chamoto Kenji、Mise Nathan、Abiko Kaoru、Baba Tsukasa、Yamaguchi Ken、Horikawa Naoki、Murakami Ryusuke、Taki Mana、Budiman Kharma、Zeng Xiang、Hosoe Yuko、Azuma Miyuki、Konishi Ikuo、Mandai Masaki
- Journal Title
  
  British Journal of Cancer
  
  Volume: 120 Issue: 1 Pages: 115-127
- DOI
  10.1038/s41416-018-0313-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-18K09308, KAKENHI-PROJECT-17K19591, KAKENHI-PROJECT-17H01587, KAKENHI-PROJECT-16H05477, KAKENHI-PROJECT-18H02945, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-18K16769, KAKENHI-PROJECT-16H06149, KAKENHI-PROJECT-17K19593
[Journal Article] Combination therapy strategies for improving PD-1 blockade efficacy: A new era in cancer immunotherapy2018
- Author(s)
  Chowdhury PS*, Chamoto K* (*equally contributed), Honjo T.
- Journal Title
  
  J Intern Med
  
  Volume: 283 Issue: 2 Pages: 110-120
- DOI
  10.1111/joim.12708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06149, KAKENHI-PROJECT-17K19593
[Journal Article] PPAR-induced fatty acid oxidation in T cells increases the number of tumor-reactive CD8+ T cells and facilitates anti*****PD-1 therapy.2018
- Author(s)
  Chowdhury PS*, Chamoto K* (*equally contributed), Kumar A, Honjo T.
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 6 Pages: 1375-1387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19593
[Journal Article] Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior2017
- Author(s)
  Miyajima M、Zhang B、Sugiura Y、Sonomura K、Guerrini MM、Tsutsui Y、Maruya M、Vogelzang A、Chamoto K、Honda K、Hikida T、Ito S、Qin H、Sanuki R、Suzuki K、Furukawa T、Ishihama Y、Matsuda F、Suematsu M、Honjo T、Fagarasan S
- Journal Title
  
  Nature Immunology
  
  Volume: 18 Issue: 12 Pages: 1342-1352
- DOI
  10.1038/ni.3867
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14579, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-15H04275, KAKENHI-PROJECT-15H04669, KAKENHI-PROJECT-16H06145, KAKENHI-PROJECT-16H06149
[Journal Article] Role of PD-1 in immunity and diseases.2017
- Author(s)
  Chamoto K*, Muna Al-Habsi* (*equally contributed), Honjo T
- Journal Title
  
  Curr Top Microbiol Immunol
  
  Volume: 198 Pages: 3757-3757
- DOI
  10.1007/82_2017_67
- ISBN
  9783319689289, 9783319689296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06149
[Journal Article] Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity.2017
- Author(s)
  Chamoto K, Chowdhury PS, Kumar A, Sonomura K, Matsuda F, Fagarasan S, Honjo T.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 5
- DOI
  10.1073/pnas.1620433114
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H06149
[Journal Article] Cancer immunotherapies targeting the PD-1 signaling pathway2017
- Author(s)
  Iwai Yoshiko、Hamanishi Junzo、Chamoto Kenji、Honjo Tasuku
- Journal Title
  
  J Biomed Sci.
  
  Volume: 24 Issue: 1 Pages: 26-26
- DOI
  10.1186/s12929-017-0329-9
- NAID
  120006309287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19591, KAKENHI-PROJECT-16H05477, KAKENHI-PROJECT-16H06149
[Journal Article] 3-Methylcholanthrene-induced transforming growth factor-beta-producing carcinomas, but not sarcomas, are refractory to regulatory T cell-depletion therapy.2010
- Author(s)
  Chamoto K, et al.
- Journal Title
  
  Cancer Science (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL : Its potentiation by combination with Th1 cell therapy2010
- Author(s)
  Takeshima T, Chamoto K, et al.
- Journal Title
  
  Cancer Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Potential differentiation of tumor bearing mouse CD11b+ Gr-1+ immature myeloid cells into both supressor macrophage and immunostimmulatory dendritic cells2009
- Author(s)
  Narita Y and Chamoto K, et.al.
- Journal Title
  
  Biomedical Research 30
  
  Pages: 7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] IFN-g-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model. Carcinogenesis2009
- Author(s)
  Wakita D, Chamoto K, et al.
- Journal Title
  
  Carcinogenesis 30
  
  Pages: 1408-1408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells.2009
- Author(s)
  Chamoto K,Takeshima T, Wakita D, Ohkuri T, Ashino S, Omatsu T, Shirato, H, Kitamura H, Nishimura T.
- Journal Title
  
  Cancer Science 100(5)
  
  Pages: 394-9
- NAID
  10025145915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinom a cells. 932009
- Author(s)
  Chamoto K, Takeshima T, Wakita D, Ohkuri T, Ashino S, Omatsu T, Shirato H, Kitamura H, Togashi Y, Nishimura T.
- Journal Title
  
  Cancer Sci. 100(5)
  
  Pages: 934-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Sialyl lewisx antigen-expressing human CD4+T and CD8+T cells as initial immune responders in memory phenotype subsets2009
- Author(s)
  Zhang Y and Chamoto K, et.al.
- Journal Title
  
  J Leukoc Biol. 84
  
  Pages: 730-735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] 免疫バランス制御の新しいパラダイム:Th1 主導免疫によるがんエスケープ機構の克服2008
- Author(s)
  茶本健司、脇田大功、西村孝司
- Journal Title
  
  先端医学社分子細胞治療 7(3)
  
  Pages: 171-180
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific Th2-cell migration into lung.2008
- Author(s)
  Ashino S., Chamoto K, et. al.
- Journal Title
  
  International Immunology 20
  
  Pages: 259-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Indispensable role of IL-6-dependent spontaneous proliferation in inducing colitogenic IL-17-producing CD8^+T cells.2008
- Author(s)
  Tajima M., Chamoto K., et. al.
- Journal Title
  
  Journal of Experimental Medicine (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer.2008
- Author(s)
  Yokouchi H., Chamoto K., et. al.
- Journal Title
  
  Cancer Science 99
  
  Pages: 361-7
- NAID
  10024002650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.2007
- Author(s)
  Zhang Y., Chamoto K, et. al.
- Journal Title
  
  International Immunology 19
  
  Pages: 151-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Combination tumor immunotherapy with radiotherapy and Th1 cell therapy against murine lung carcinoma.2007
- Author(s)
  Yokouchi H, Chamoto K(第一著者と同等に貢献), et. al.
- Journal Title
  
  Clinical & Experimental Metastasis 24
  
  Pages: 533-540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Blocking of IL-6 signaling pathway prevents CD4_+T cell-mediated colitis in a T(h)17-independent manner. Int Immunol.2007
- Author(s)
  Noguchi D., Chamoto K, et. al.
- Journal Title
  
  International Immunology 19
  
  Pages: 1431-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Combination tumor immunotherapy with radiotherapy and Th1 cell therapy against murine lung carcinoma.2007
- Author(s)
  Yokouchi H, Chamoto K (第一著者と同等に貢献), Wakita D, Yamazaki K, Shirato H, Takeshima T, Dosaka-Akita H, Nishimura M, Yue Z, Kitamura H, Nishimura T.
- Journal Title
  
  Clinical & Experimental Metastasis. 24
  
  Pages: 533-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Identification of novel helper epitopes of MAGE-A4 tumour antigen : useful tool for the propagation of Thl cells
- Author(s)
  Ohkuri T and Chamoto K, et.al.
- Journal Title
  
  Br J Cancer (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Journal Article] Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio-and immuno-resistant lung carcinoma cells
- Author(s)
  Kenji Chamoto, Takashi Nismura, et.al.
- Journal Title
  
  Cancer Science (印刷中)
- NAID
  10025145915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790351
[Patent] ＰＤ－１シグナル阻害剤含有薬剤による治療有効性の予測及び／又は判定マーカー2019
- Inventor(s)
  本庶佑、茶本健司、松田文彦
- Industrial Property Rights Holder
  本庶佑、茶本健司、松田文彦
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] PD-1シグナル阻害剤の併用療法2019
- Inventor(s)
  本庶佑、茶本健司, Fagarasan Sidonia
- Industrial Property Rights Holder
  本庶佑、茶本健司, Fagarasan Sidonia
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-205550
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] ＰＤ－１シグナル阻害剤含有薬剤による治療有効性の予測及び／又は判定マーカー2019
- Inventor(s)
  本庶佑、茶本健司、松田文彦、Fagarasan Sidonia
- Industrial Property Rights Holder
  本庶佑、茶本健司、松田文彦、Fagarasan Sidonia
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-000181
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K19593
[Patent] 免疫チェックポイント阻害剤の奏効性の判定を補助する方法、試薬キット、装置及びコンピュータプログラム2019
- Inventor(s)
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Holder
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K19593
[Patent] ＰＤ－１シグナル阻害剤含有薬剤による治療有効性の予測及び／又は判定マーカー2019
- Inventor(s)
  本庶佑、茶本健司、松田文彦
- Industrial Property Rights Holder
  本庶佑、茶本健司、松田文彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-000181
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] 免疫チェックポイント阻害剤の奏効性の判定を補助する方法、試薬キット、装置及びコンピュータプログラム2019
- Inventor(s)
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Holder
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] 免疫チェックポイント阻害剤の奏効性の判定を補助する方法、試薬キット、装置及びコンピュータプログラム2019
- Inventor(s)
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Holder
  本庶佑、茶本健司、林秀敏、中川和彦、後藤恵、宇賀均
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] がんの判定方法、がんの判定のための装置及びコンピュータプログラム2016
- Inventor(s)
  本庶佑、茶本健司、後藤恵、宇賀仁
- Industrial Property Rights Holder
  本庶佑、茶本健司、後藤恵、宇賀仁
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-27
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] ＰＤ－１シグナル阻害剤の併用療法2016
- Inventor(s)
  本庶佑、茶本健司、Fagarasan Sidonia
- Industrial Property Rights Holder
  本庶佑、茶本健司、Fagarasan Sidonia
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-05
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] PD-1抗体による癌治療における有効性判定マーカー2016
- Inventor(s)
  本庶佑、茶本健司、松田文彦、Fagarasan Sidonia
- Industrial Property Rights Holder
  本庶佑、茶本健司、松田文彦、Fagarasan Sidonia
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-214785
- Filing Date
  2016-11-02
- Data Source
  KAKENHI-PROJECT-16H06149
[Patent] PD-1シグナル阻害剤の併用療法2015
- Inventor(s)
  本庶佑、茶本健司
- Industrial Property Rights Holder
  本庶佑、茶本健司
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-07
- Data Source
  KAKENHI-PROJECT-15H06331
[Patent] 免疫状態の活性化した被検者由来の液体試料の判別方法及びその利用2015
- Inventor(s)
  本庶佑、茶本健司、後藤恵、宇賀仁
- Industrial Property Rights Holder
  本庶佑、茶本健司、後藤恵、宇賀仁
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-28
- Data Source
  KAKENHI-PROJECT-15H06331
[Presentation] 免疫代謝解析によるPD-1抗体がん免疫治療の効果予測マーカーの同定とその意義2019
- Author(s)
  茶本健司
- Organizer
  第23回日本がん免疫学会シンポジウム５
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害がん免疫治療法のおける免疫代謝の役割2019
- Author(s)
  茶本健司
- Organizer
  北海道大学部局横断シンポジウム、札幌、2019年1月25日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Improvement of the PD-1 blockade cancer immunotherapy by regulating immune metabolism2019
- Author(s)
  Chamoto K.
- Organizer
  第４８回日本免疫学会学術集会シンポジウム３
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害抗体治療抵抗性の克服に向けた併用治療とバイオマーカーの開発2019
- Author(s)
  茶本健司
- Organizer
  難治性がんの克服について語る会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害がん免疫治療法のおける免疫代謝の役割2019
- Author(s)
  茶本健司
- Organizer
  北海道大学部局横断シンポジウム、札幌、2019年1月25日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] Advances in PD-1 blockade cancer immunotherapy: important roles of immune metabolism2019
- Author(s)
  Chamoto K.
- Organizer
  The 27th ICNIM in Sapporo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] がん免疫と放射線治療の接点：PD-1抗体治療との併用治療戦略2019
- Author(s)
  茶本健司
- Organizer
  日本放射線腫瘍学会第32回学術大会シンポジウム１
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Cancer Immunotherapy and Immune Metabolism2019
- Author(s)
  Chamoto K.
- Organizer
  PROTEIN ISLAND MATSUYAMA 2019 International Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Radiation therapy links to cancer immunotherapy by immune T cells2019
- Author(s)
  Chamoto K.
- Organizer
  GI-Core symposium in Hokkaido Univ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害がん免疫治療の新展開：免疫代謝を考慮した併用治療とバイオマーカーの開発2019
- Author(s)
  茶本健司
- Organizer
  第34回日本肺癌学会ワークショップスイーツセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Metabplic biomarkers for the PD-1 blockade cancer immunotherapy in NSCLC patients.2019
- Author(s)
  Chamoto K.
- Organizer
  The 78th JCA Symposium 1
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝を中心としたPD-1阻害抗体効果予測バイオマーカーの開発2019
- Author(s)
  茶本健司
- Organizer
  第7回がんと代謝研究会セッション9
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝解析によるPD-1抗体がん免疫治療の効果予測マーカーの探索2019
- Author(s)
  茶本健司
- Organizer
  第19回日本抗加齢医学会総会若手プログラ2
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Soluble immune-checkpoint factors as a predictive biomarker for nivolumab treatment in advanced NSCLC patients First results of Nivolution trial2019
- Author(s)
  Chamoto K.
- Organizer
  2019 JSMO annual meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝を考慮したPD-1阻害がん免疫治療の治療効果予測バイオマーカー2019
- Author(s)
  茶本健司
- Organizer
  第23回日本がん分子標的治療学会学術集会シンポジウム４
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PPAR-induced fatty acid oxidation in T cells ameliorates the antitumor activity of PD-L1 blockade.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  第77回日本癌学会学術総会シンポジウムS1、大阪、2018年9月27日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫チェックポイント阻害薬の臨床における問題点とその取り組み：基礎と臨床は如何にして融合すべきか？2018
- Author(s)
  茶本健司
- Organizer
  第6回日本臨床腫瘍学会近畿地区セミナー、2018年6月23日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] 免疫代謝制御によるPD-1阻害がん免疫治療の増強効果2018
- Author(s)
  茶本健司
- Organizer
  第1回京都大学腫瘍免疫勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] VISTA in tumor cells regulates T cell function2018
- Author(s)
  Junzo Hamanishi, Kumuruz Murat, Kenji Chamoto, Nathan Mise, Kaoru Abiko, Tsukasa Baba, Ryusuke Murakami, Miyuki Azuma, Masaki Mandai
- Organizer
  45th Naito Conference
- Data Source
  KAKENHI-PROJECT-18H02945
[Presentation] 脂質代謝制御によるPD-1阻害がん免疫治療の増強効果とその機序解明2018
- Author(s)
  茶本健司
- Organizer
  第55回日本臨床分子医学会学術集会、京都 4月12日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] The role of fatty acid oxidation of T cells in the synergistic effect with PD-1 blockade2018
- Author(s)
  Chamoto K.
- Organizer
  The 6th JCA-AACR Special joint Conference, July 12th, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] 免疫代謝とPD-1阻害がん免疫治療2018
- Author(s)
  茶本健司
- Organizer
  第３回京都皮膚基礎研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] The role of fatty acid oxidation of T cells in the synergistic effect with PD-1 blockade2018
- Author(s)
  Chamoto K.
- Organizer
  The 6th JCA-AACR Special joint Conference, July 12th, Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  2nd International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer. June 14th-15th, Trondheim, Norway.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] PD-1阻害がん免疫治療におけるT細胞脂質代謝の重要性2018
- Author(s)
  茶本健司
- Organizer
  第22回日本がん免疫学会シンポジウム4, 岡山、2018年8月2日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] Energy metabolism regulation in T cells improves the efficacy of the PD-1 blockade cancer immunotherapy.2018
- Author(s)
  Chamoto K.
- Organizer
  Novartis Asian-Pacific Summit 2018, July 14th, Taipei.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 代謝シグナル分子を標的とした腫瘍免疫学の新展開2018
- Author(s)
  茶本健司
- Organizer
  ランチョンセミナー２、岡山、2018年8月3日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] ミトコンドリア活性化剤によるPD-1阻害免疫治療の併用効果とその作用機序解明2018
- Author(s)
  茶本健司
- Organizer
  九州肺がん治療懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PPAR-induced fatty acid oxidation in T cells ameliorates the antitumor activity of PD-L1 blockade.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  第77回日本癌学会学術総会シンポジウムS1、大阪、2018年9月27日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] Modulation of fatty acid oxidation in T cells improves the PD-1 blockade therapy.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  第45回内藤コンファレンスがん免疫治療法の免疫分子基盤-次世代のがん免疫療法をめざして、札幌 6月28日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] 脂質代謝制御によるPD-1阻害がん免疫治療の増強効果とその機序解明2018
- Author(s)
  茶本健司
- Organizer
  第55回日本臨床分子医学会学術集会、京都 4月12日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Energy metabolism regulation in T cells improves the efficacy of the PD-1 blockade cancer immunotherapy.2018
- Author(s)
  Chamoto K.
- Organizer
  Novartis Asian-Pacific Summit 2018, July 14th, Taipei.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] Modulation of fatty acid oxidation in T cells improves the PD-1 blockade therapy.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  第45回内藤コンファレンスがん免疫治療法の免疫分子基盤-次世代のがん免疫療法をめざして、札幌 6月28日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2018
- Author(s)
  Chamoto K, Honjo T.
- Organizer
  2nd International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer. June 14th-15th, Trondheim, Norway.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T細胞の脂肪酸酸化を介したPD-1阻がん免疫治療の増強とその機序解明2018
- Author(s)
  茶本健司
- Organizer
  Japan/Joy of Fatty Acids Secrets/Society (JFAS)
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝促進によるPD-1阻害治療の増強効果とその作用機序解明2018
- Author(s)
  茶本健司
- Organizer
  平成29年度がん研究シンポジウム：次世代免疫療法・ゲノム医療
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害がん免疫治療におけるT細胞脂質代謝の重要性2018
- Author(s)
  茶本健司
- Organizer
  第22回日本がん免疫学会シンポジウム4, 岡山、2018年8月2日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] VISTA expressed in tumor cells regulates T cell function VISTA expressed in tumor cells regulates T cell function2018
- Author(s)
  Murat Kumuruz, 濱西潤三, 松村謙臣, 茶本健司, 三瀬名丹, 安彦郁, 馬場長, 山口建, 村上隆介, 細江裕子, 東みゆき, 小西郁夫, 万代昌紀
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02945
[Presentation] PD-1阻害がん免疫治療法の最前線2018
- Author(s)
  茶本健司
- Organizer
  第120回兵庫県皮膚科医会、神戸、2018年6月30日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Regulation of immune metabolism improves the PD-1 blockade cancer immunotherapy2018
- Author(s)
  Kenji Chamoto
- Organizer
  日本免疫学会ランチョンテクニカルセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1阻害がん免疫治療法の最前線2018
- Author(s)
  茶本健司
- Organizer
  第120回兵庫県皮膚科医会、神戸、2018年6月30日
- Invited
- Data Source
  KAKENHI-PROJECT-17K19593
[Presentation] 免疫チェックポイント阻害薬の臨床における問題点とその取り組み：基礎と臨床は如何にして融合すべきか？2018
- Author(s)
  茶本健司
- Organizer
  第6回日本臨床腫瘍学会近畿地区セミナー、2018年6月23日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 代謝シグナル分子を標的とした腫瘍免疫学の新展開2018
- Author(s)
  茶本健司
- Organizer
  第22回日本がん免疫学会ランチョンセミナー２、岡山、2018年8月3日
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝に着目した次世代がん免疫治療法と効果予測バイオマーカー2018
- Author(s)
  茶本健司
- Organizer
  Lung Cancer expert seminar
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  The 36th Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝制御によるがん免疫応答の増強2017
- Author(s)
  茶本健司
- Organizer
  第45回日本臨床免疫学会合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T細胞のエネルギー代謝に注目したPD-1阻害がん免疫治療の新しい展開2017
- Author(s)
  茶本健司
- Organizer
  第48回京都造血幹細胞移植研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  Yonsei University International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Energy metabolism improves the PD-1 blockade cancer immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  日本癌学会奨励賞シンポジウム第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  第36回札幌がん国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T cell energy metabolism regulates PD-1 blockade-mediated anti-tumor effect.2017
- Author(s)
  Kenji Chamoto
- Organizer
  RIKEN IMS-JSI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Modulation of energy metabolism in T cells enhances the efficacy of PD-1 blockade immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  Japanese society of medical oncology (JASMO)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T cell energy metabolism regulates anti-tumor effect mediated by PD-1 blockade.2017
- Author(s)
  Kenji Chamoto
- Organizer
  日本がん免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves the PD-1 blockade cancer therapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  Leibniz-AMED Workshop on Immune Regulation of Diseases and Aging.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial manipulation improves PD-1 blockade immunotherapy.2017
- Author(s)
  Kenji Chamoto
- Organizer
  Peking University International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T細胞のエネルギー代謝とPD-1阻害がん免疫治療の増強効果2017
- Author(s)
  茶本健司
- Organizer
  BD学術セミナー 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 免疫代謝制御によるPD-1阻害がん免疫治療の増強効果2017
- Author(s)
  茶本健司
- Organizer
  第36回セルセラピーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T細胞のエネルギー代謝に注目したPD-1阻害がん免疫治療の新しい展開2017
- Author(s)
  茶本健司
- Organizer
  39回文部科学省がんプロフェッショナル養成基盤推進プラン
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 日進月歩するPD-1阻害がん免疫治療2017
- Author(s)
  茶本健司
- Organizer
  東北RCCセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] PD-1を標的とした免疫チェックポイント阻害療法2016
- Author(s)
  茶本健司
- Organizer
  第78回日本血液学会学術集会、教育講演
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial modulation improves PD-1 blockade cancer immunotherapy2016
- Author(s)
  Kenji Chamoto
- Organizer
  京都賞ワークショップ
- Place of Presentation
  京都国際会館
- Year and Date
  2016-11-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Mitochondrial activation of comprehensive tumor-specific CTLs during PD-1 blockade therapy2016
- Author(s)
  Chamoto K, Chowdhury PS, Honjo T
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association, International Session
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] Priming CD8+ T cells in DLN accelerates the accumulation of CTLs in tumor sites via MIG/CXCR3 axis in PD-1 blockade therapy.2016
- Author(s)
  Chamoto K, Chowdhury PS, Honjo T
- Organizer
  第20回日本がん免疫学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] T細胞のエネルギー代謝とPD-1抗体の抗腫瘍効果2016
- Author(s)
  茶本健司
- Organizer
  第5回日本免疫・細胞治療学会学術総会、シンポジウム
- Place of Presentation
  秋葉原UDX
- Year and Date
  2016-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] 抗PD-1抗体の開発とがん免疫治療の進展2016
- Author(s)
  茶本健司
- Organizer
  第52回姫路市医師会夏季大学講演会、シンポジウム
- Place of Presentation
  兵庫県姫路市
- Year and Date
  2016-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-16H06149
[Presentation] CD133^+癌幹細胞に高発現するuPAは活性型TGF-β産生促進を介してTregを誘導する2009
- Author(s)
  茶本健司, et al.
- Organizer
  第13回がん免疫学会総会
- Place of Presentation
  福岡、北九州国際会議場
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] uPA overexpressed in cancer stem cell promote the immunosuppressive tumor escape via TGF-β-Treg axis2009
- Author(s)
  Chamoto K, et al.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] A crucial role of cancer stem cell for the regulation of immunosuppressive tumor escape via Treg induction.2009
- Author(s)
  Chamoto K, et al.
- Organizer
  American Association for Cancer Research 100th Annual Meeting.
- Place of Presentation
  USA, Colorado Convention Cente, Denver
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Urokinase-type plasminogen activator overexpressed in cancer stem cell promote the immunosuppressive tumor escape via TGF-β-Treg axis2009
- Author(s)
  茶本健司, et al.
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 癌幹細胞によるTregを介した新規免疫抑制機構の解明2008
- Author(s)
  茶本健司
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] TGF-beta high-producing ability of mouse carcinomas determines their refractoriness against Treg-depletion therapy.2008
- Author(s)
  Takashi Nishimura, Daiko Wakita, Masaki Tajima and Kenji Chamoto.
- Organizer
  12th International Conference on Lymphocyte Activation and Immune Regulation.
- Place of Presentation
  California
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] TGF-beta high-producing ability of mouse carcinomas determines their refractoriness against Treg-depletion therapy.2008
- Author(s)
  Takashi Nishimura., Kenji Chamoto.
- Organizer
  12th International Conference on Lymphocyte Activati on and Immune Regulation.
- Place of Presentation
  Fairmont Newport Beach Hotel
- Year and Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] Treg誘導を介した癌幹細胞の免疫抑制機構の解明2008
- Author(s)
  茶本健司
- Organizer
  第67回日本癌学学会術総会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] 担癌生体内のTregを介した免疫抑制機構の解明メチルコラントレン誘発性上皮癌と肉腫のTGF-b産生能力の違いとその意義2008
- Author(s)
  茶本健司
- Organizer
  第12回基盤的癌免疫研究会総会
- Place of Presentation
  埼玉県大宮ソニックシティ
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] A crucial role of cancer stem cell for the regulation of immunosuppressive tumor escape via Treg induction癌幹細胞によるTregを介した新規免疫抑制機構の解明2008
- Author(s)
  茶本健司、脇田大功、打浪雄介、大栗敬幸、西村孝司
- Organizer
  第38 回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] A crucial role of cancer stem cell for the regulation of immunosuppressive tumor escape via Treg induction. Treg誘導を介した癌幹細胞の免疫抑制機構の解明2008
- Author(s)
  茶本健司、脇田大功、成田義規、大栗敬幸、打浪雄介、富樫裕二、北村秀光、西村孝司
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] 担癌生体内のTregを介した免疫抑制機構の解明メチルコラントレン誘発性上皮癌と肉腫のTGF-ss産生能力の違いとその意義2008
- Author(s)
  茶本健司、脇田大功、成田義規、富樫裕二、北村秀光、西村孝司
- Organizer
  第12 回基盤的癌免疫研究会総会抄録
- Place of Presentation
  埼玉県さいたま市大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] CpG癌ワクチンと放射線併用治療による上皮性癌治療法の開発2007
- Author(s)
  茶本健司、脇田大功、武島英嗣、張悦、白土博樹、北村秀光、西村孝司
- Organizer
  第11 回基盤的癌免疫研究会総会抄録
- Place of Presentation
  東京大学鉄門記念講堂
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] CpG癌ワクチンと放射線併用治療による上皮性癌治療法の開発2007
- Author(s)
  茶本健司、脇田大功、武島英嗣、張悦、白土博樹、北村秀光、西村孝司
- Organizer
  第11回基盤的癌免疫研究会総会
- Place of Presentation
  東京大学鉄門記念講堂
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] CpG癌ワクチンと放射線併用治療による上皮性癌治療法の開発2007
- Author(s)
  茶本健司、脇田大功、武島英嗣、張悦、白土博樹、北村秀光、西村孝司
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] Differential role of Treg-mediated immunosupression between carcinoma- and sarcoma-bearing mice2007
- Author(s)
  Kenji Chamoto, Daiko Wakita, Yoshinori Narita, Zhang Yue, Hidemitsu Kitamura, Takashi Nishimura
- Organizer
  第37回日本免疫学会総会・学術集会記録
- Place of Presentation
  東京グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] CpG癌ワクチンと放射線併用治療による上皮性癌治療法の開発2007
- Author(s)
  茶本健司、脇田大功、武島英嗣、張悦、白土博樹、北村秀光、西村孝司
- Organizer
  第66 回日本癌学会総会・学術会記録
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790351
[Presentation] 原発性上皮癌と肉腫におけるTregを介した免疫抑制機構の解明2007
- Author(s)
  茶本健司、脇田大功、成田義規、張悦、北村秀光、西村孝司
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  グランドプリンスホテル新高輪
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790351

1. Hamanishi Junzo (80378736)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. 滝真奈 (20898077)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAM Jin-min (60414132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIRATO Hiroki (20187537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. ONODERA Yasuhito (90435561)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SHIMIZU Shinichi (50463724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAO Seishin (10614216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 万代昌紀 (80283597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. 安彦郁 (20508246)

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Chamoto Kenji 茶本 健司

CHAMOTO Kenji 茶本 健司

Research Projects

Research Products

Co-Researchers

Elucidation of tertiary lymphoid structures (TLS) in gynecological cancer and basic investigation of new treatment development

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Identification of neoantigens promoting inflammagingPrincipal Investigator

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Impact of circulating exhausted T cells with different stages on PD-1 blockade caner immunotherapyPrincipal Investigator

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Investigation of B-cell immunity against gynecological cancer and new strategies for diagnosis and treatment

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Novel diagnostic and therapeutic strategies for ovarian cancer by investigation of cancer and host diversity

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Research and development about helium and proton hybrid system with proton CT and Immuno-radiotherapy

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Investigation of immune-suppressive dynamism and exploratory research for new treatment strategy for gynecologic cancer

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Identification of PD-1 blocked responsive genes and functional analysis based on tumor eradication system in vivo.Principal Investigator

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Elucidation of anti-tumor immune mechanism including Treg inhibition by PD-1 blockade.Principal Investigator

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抗PD-1抗体による抗腫瘍免疫応答の解明Principal Investigator

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Research for Real-time Tracking Medical Science

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The development of type-1 tumor immunotherapy based on removing immunosupression from tumor-bearerPrincipal Investigator

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[Book] Bio Clinica 352020

Author(s)

Publisher

Chamoto Kenji 茶本健司

CHAMOTO Kenji 茶本健司

[Book] がん免疫成立の基盤となるCancer-Immunity Cycle　第４回　ステップ７～１2020

[Book] メディカル・サイエンス・ダイジェスト 45(2),95-98. 祝　本庶佑ノーベル賞受賞記念特集号　がん免疫治療の新展開：免疫代謝とPD－１阻害剤2019

[Book] メディカル・サイエンス・ダイジェスト 45(2),95-98. 祝　本庶佑ノーベル賞受賞記念特集号　がん免疫治療の新展開：免疫代謝とPD－１阻害剤2019

[Book] The Lipid 第134号　特集：免疫と代謝の接点：イムノメタボリズム, 30(2),195-202. イムノメタボリズムの新たな展開：がんとイムノメタボリズム2019

[Book] 生体の科学 70（３）　特集：免疫チェックポイントによる免疫制御, in press. PD-1/PD-L1による免疫制御2019

[Book] 生体の科学 70（３）　特集：免疫チェックポイントによる免疫制御, in press. PD-1/PD-L1による免疫制御2019

[Book] The Lipid 第134号　特集：免疫と代謝の接点：イムノメタボリズム, 30(2),195-202. イムノメタボリズムの新たな展開：がんとイムノメタボリズム2019