SHIBATA SHIGERU 柴田茂

… Alternative Names

Shibata Shigeru 柴田茂

柴田茂シバタシゲル

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Researcher Number	60508068
Other IDs
Affiliation (Current)	2025: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 帝京大学, 医学部, 教授 2017 – 2023: 帝京大学, 医学部, 教授 2014 – 2017: 帝京大学, 医学部, 准教授 2009: 東大, 医学部附属病院
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Basic Section 54040:Metabolism and endocrinology-related / Eating habits
Keywords	Principal Investigator 体液恒常性 / 翻訳後修飾 / 高血圧 / 慢性腎臓病 / 食塩感受性 / 膜輸送体 / リン酸化 / 腎臓内科学 / 臓器連関 / 代謝異常 … More / 尿細管 / 肥満糖尿病 / ユビキチンプロテアソーム / エクソソーム / ミネラル代謝 / 食塩感受性高血圧 / 局所制御 / リガンド / ステロイド受容体 / ビタミンD受容体 / pendrin / ミネラルコルチコイド受容体 / 電解質調節 / ミネラロコルチコイド受容体 / ユビキチンリガーゼ / 電解質異常 / 核内受容体 / ユビキチン・プロテアソーム系 / 鉱質コルチコイド受容体 … More Except Principal Investigator 高血圧 / ミネラルコルチコイド / カリウム代謝 / リン酸化 / KLHL3 / 腎尿細管ナトリウム輸送体 / 糖尿病 / 尿細管 / ナトリウム輸送 / 生理学 / 高血圧学 / コルチゾール / 内科 / DOHaD / ミネラルコルチコイド受容体 / 加齢 / 糖尿病性腎臓病 / 食塩感受性高血圧 / アルドステロン / 腎臓病 / エピジェネティクス / 環境因子 / 糖質コルチコイド / 鉱質コルチコイド / ミネラロコルチコイド受容体 / 機能性食品 / 生活の質 / 低カリウム野菜 / 高カリウム血症 / 血液透析 / 慢性腎臓病 / 腎障害 Less

赤血球・血管内皮・腎尿細管の連関によるカリウム制御機構の解明とヒトへの応用Principal Investigator
- Principal Investigator
  
  柴田茂
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Teikyo University
臓器連関によるカリウム調節の分子基盤解明と"gut factor"の探索
- Principal Investigator
  
  石澤健一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Sodium-bicarbonate cotransporter NBCe1 affects hypertension and diabetes via sodium reabsorption.
- Principal Investigator
  
  Yamazaki Osamu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Teikyo University
Regulation of nuclear receptor through autophagy-related proteins and other mechanismsPrincipal Investigator
- Principal Investigator
  
  Shibata Shigeru
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Teikyo University
Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseasesPrincipal Investigator
- Principal Investigator
  
  Shibata Shigeru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Satisfaction and usefulness of low potassium vegetables for patients with chronic kidney disease
- Principal Investigator
  
  Uchida Shunya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Teikyo University
生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索
- Principal Investigator
  
  FUJITA Toshiro
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseasesPrincipal Investigator
- Principal Investigator
  
  Shibata Shigeru
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Teikyo University
Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction
- Principal Investigator
  
  FUJITA Toshiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
翻訳後修飾による細胞選択的な鉱質コルチコイド受容体制御系の全容解明Principal Investigator
- Principal Investigator
  
  柴田茂
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Kidney internal medicine
- Research Institution
  Teikyo University
慢性腎臓病進展におけるRac-MR経路の関与とRac1阻害薬の有用性Principal Investigator
- Principal Investigator
  
  柴田茂
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] Hypertension: A Companion to Braunwald's Heart Disease, 3rd Edition, Edited by George L. Bakris、Matthew Sorrentino Chapter 24 “Renin Angiotensin Aldosterone System Blockers”2017
- Author(s)
  Shibata S, Fujita T
- Publisher
  ELSEVIER
- ISBN
  9780323429733
- Data Source
  KAKENHI-PROJECT-15H05788
[Book] Bakris: Hypertension, 3e2016
- Author(s)
  Shigeru Shibata, Toshiro Fujita
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Nicorandil protects podocytes via modulation of antioxidative capacity in acute puromycin aminonucleoside-induced nephrosis in rats2023
- Author(s)
  Yamanaka Masaki、Tamura Yoshifuru、Kuribayashi-Okuma Emiko、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 324 Issue: 2 Pages: F168-F178
- DOI
  10.1152/ajprenal.00144.2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Mineralocorticoid Receptor Antagonists for Preventing Chronic Kidney Disease Progression: Current Evidence and Future Challenges2023
- Author(s)
  Fujii Wataru、Shibata Shigeru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 9 Pages: 7719-7719
- DOI
  10.3390/ijms24097719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Current situation of telemedicine research for cardiovascular risk in Japan2023
- Author(s)
  Shibata Shigeru、Hoshide Satoshi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 5 Pages: 1171
- DOI
  10.1038/s41440-023-01224-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Selenium Associates With Response to Erythropoiesis-Stimulating Agents in Hemodialysis Patients2022
- Author(s)
  Yasukawa Minoru、Arai Shigeyuki、Nagura Michito、Kido Ryo、Asakawa Shinichiro、Hirohama Daigoro、Yamazaki Osamu、Tamura Yoshifuru、Fujimaki Michitaka、Kobayashi Sawako、Mimaki Masakazu、Kodama Hiroko、Uchida Shunya、Fujigaki Yoshihide、Shibata Shigeru
- Journal Title
  
  Kidney International Reports
  
  Volume: 7 Issue: 7 Pages: 1565
- DOI
  10.1016/j.ekir.2022.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-192022
- Author(s)
  Shibata Shigeru、Kobayashi Kazuo、Tanaka Masami、Asayama Kei、Yamamoto Eiichiro、Nakagami Hironori、Hoshide Satoshi、Kishi Takuya、Matsumoto Chisa、Mogi Masaki、Morimoto Satoshi、Yamamoto Koichi、Mukoyama Masashi、Kario Kazuomi、Node Koichi、Rakugi Hiromi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 3 Pages: 589
- DOI
  10.1038/s41440-022-01134-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] SLC23A3 is a renal hypoxanthine transporter2022
- Author(s)
  Makoto Hosoyamada, Naoko H. Tomioka, Tamaki Watanabe, Nobuhiro Yasuno, Shunya Uchida, Shigeru Shibata
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 41 Issue: 12 Pages: 1279
- DOI
  10.1080/15257770.2022.2028826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08222, KAKENHI-PROJECT-20K11598, KAKENHI-PROJECT-19H03678
[Journal Article] Long COVID and hypertension-related disorders: a report from the Japanese Society of Hypertension Project Team on COVID-192022
- Author(s)
  Matsumoto Chisa、Shibata Shigeru、Kishi Takuya、Morimoto Satoshi、Mogi Masaki、Yamamoto Koichi、Kobayashi Kazuo、Tanaka Masami、Asayama Kei、Yamamoto Eiichiro、Nakagami Hironori、Hoshide Satoshi、Mukoyama Masashi、Kario Kazuomi、Node Koichi、Rakugi Hiromi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 3 Pages: 601
- DOI
  10.1038/s41440-022-01145-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Thermoreceptor TRPV1 regulates body weight and blood pressure in the absence of thermogenin2022
- Author(s)
  Shibata Shigeru
- Journal Title
  
  Hypertension Research
  
  Volume: 45 Issue: 5 Pages: 917
- DOI
  10.1038/s41440-022-00867-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Severe COVID-19 and preexisting hypertension: a matter of age?2022
- Author(s)
  Yamazaki Osamu、Shibata Shigeru
- Journal Title
  
  Hypertension Research
  
  Volume: 45 Issue: 9 Pages: 1523
- DOI
  10.1038/s41440-022-00978-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] Updates on Renin-Angiotensin System Blockers in Hypertensive Patients With COVID-192021
- Author(s)
  Shibata Shigeru、Kishi Takuya
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 34 Issue: 11 Pages: 1145
- DOI
  10.1093/ajh/hpab130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03678
[Journal Article] A novel I551F variant of the Naþ/HCO3- cotransporter NBCe1-A shows reduced cell surface expression, resulting in diminished transport activity2021
- Author(s)
 Yamazaki Osamu、Yamashita Maho、Li Jinping、Ochiai-Homma Fumika、Yoshida Tadashi、Hirahashi Junichi、Furukawa Taiji、Kozuma Ken、Fujigaki Yoshihide、Seki George、Hayashi Matsuhiko、Shibata Shigeru
- Journal Title
 
 American Journal of Physiology-Renal Physiology
 
 Volume: 321 Issue: 6 Pages: F771-F784
- DOI
 10.1152/ajprenal.00584.2020
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-21K08566
[Journal Article] Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism2021
- Author(s)
  Ochiai-Homma F, Kuribayashi-Okuma E, Tsurutani Y, Ishizawa K, Fujii W, Odajima K, Kawagoe M, Tomomitsu Y, Murakawa M, Asakawa S, Hirohama D, Nagura M, Arai S, Yamazaki O, Tamura Y, Fujigaki Y, Nishikawa T, Shibata S
- Journal Title
  
  Hypertens Res
  
  Volume: 44 Issue: 12 Pages: 1557
- DOI
  10.1038/s41440-021-00710-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-19K17719
[Journal Article] Activation of Rac1-Mineralocorticoid Receptor Pathway Contributes to Renal Injury in Salt-Loaded db/db Mice2021
- Author(s)
  Hirohama Daigoro、Nishimoto Mitsuhiro、Ayuzawa Nobuhiro、Kawarazaki Wakako、Fujii Wataru、Oba Shigeyoshi、Shibata Shigeru、Marumo Takeshi、Fujita Toshiro
- Journal Title
  
  Hypertension
  
  Volume: 78 Issue: 1 Pages: 82
- DOI
  10.1161/hypertensionaha.121.17263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21596, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-19H03678
[Journal Article] Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice.2021
- Author(s)
  Hirohama D, Nishimoto M, Ayuzawa N, Kawarazaki W, Fujii W, Oba S, Shibata S, Marumo T, Fujita T.
- Journal Title
  
  Hypertension
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788
[Journal Article] Xanthine Oxidoreductase Inhibitors Suppress the Onset of Exercise-Induced AKI in High HPRT Activity Urat1-Uox Double Knockout Mice2021
- Author(s)
  Hosoya Takuji、Uchida Shunya、Shibata Shigeru、Tomioka Naoko H.、Matsumoto Koji、Hosoyamada Makoto
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 33 Issue: 2 Pages: 326
- DOI
  10.1681/asn.2021050616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11598, KAKENHI-PROJECT-19H03678
[Journal Article] Upregulation of renal Na–K–2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway2020
- Author(s)
  Sakai Kazuhiro、Yamazaki Osamu、Ishizawa Kenichi、Tamura Yoshifuru、Wang Qin、Ueno Masaki、Hayama Yuto、Fujigaki Yoshihide、Shibata Shigeru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 3 Pages: 710
- DOI
  10.1016/j.bbrc.2020.01.142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22643, KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia2020
- Author(s)
  Omizo Hiroki、Tamura Yoshifuru、Morimoto Chikayuki、Ueno Masaki、Hayama Yuto、Kuribayashi-Okuma Emiko、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 9326-9326
- DOI
  10.1038/s41598-020-65706-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] ABCG2 expression and uric acid metabolism of the intestine in hyperuricemia model rat2020
- Author(s)
  Morimoto Chikayuki、Tamura Yoshifuru、Asakawa Shinichiro、Kuribayashi-Okuma Emiko、Nemoto Yoshikazu、Li Jinping、Murase Takayo、Nakamura Takashi、Hosoyamada Makoto、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 39 Issue: 5 Pages: 744
- DOI
  10.1080/15257770.2019.1694684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model2020
- Author(s)
  Wang Qin、Ishizawa Kenichi、Li Jinping、Fujii Wataru、Nemoto Yoshikazu、Yamazaki Osamu、Tamura Yoshifuru、Miura Yutaka、Nie Xuedan、Abe Ryo、Segawa Hiroko、Kuro-O Makoto、Shibata Shigeru
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 575-575
- DOI
  10.1038/s42003-020-01298-1
- URL
  https://pure.teikyo.jp/en/publications/7532e70c-abd5-4756-9e5a-a53e9d047356
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Pgi2 analog attenuates salt-induced renal injury through the inhibition of inflammation and rac1-mr activation2020
- Author(s)
 Hirohama Daigoro、Kawarazaki Wakako、Nishimoto Mitsuhiro、Ayuzawa Nobuhiro、Marumo Takeshi、Shibata Shigeru、Fujita Toshiro
- Journal Title
 
 International Journal of Molecular Sciences
 
 Volume: 21 Issue: 12 Pages: 1
- DOI
 10.3390/ijms21124433
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-19K08672, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia2020
- Author(s)
  Hiroki Omizo, Yoshifuru Tamura, Chikayuki Morimoto, Masaki Ueno, Yuto Hayama, Emiko Kuribayashi-Okuma, Shunya Uchida, and Shigeru Shibata
- Journal Title
  
  Scientific Reports
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22643
[Journal Article] 25(OH)D3 stimulates the expression of vitamin D target genes in renal tubular cells when Cyp27b1 is abrogated2020
- Author(s)
 Kikuyama T, Susa T, Tamamori-Adachi M, Iizuka M, Akimoto M, Okinaga H, Fujigaki Y, Uchida S, Shibata S, Okazaki T.
- Journal Title
 
 J Steroid Biochem Mol Biol .
 
 Volume: 199 Pages: 105593-105593
- DOI
 10.1016/j.jsbmb.2020.105593
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K09699, KAKENHI-PROJECT-19K11651, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-17K09891, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19K22643
[Journal Article] Role of the ubiquitin proteasome system in the regulation of blood pressure: A review2020
- Author(s)
  Yamazaki Osamu、Hirohama Daigoro、Ishizawa Kenichi、Shibata Shigeru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 15 Pages: 1
- DOI
  10.3390/ijms21155358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-19K22643
[Journal Article] 【腎臓学　この一年の進歩】集合管の生理学と水電解質調節の新知見2019
- Author(s)
  柴田　茂
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 61 Pages: 7-10
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Phosphate binding by sucroferric oxyhydroxide ameliorates renal injury in the remnant kidney model2019
- Author(s)
  Yoshikazu Nemoto, Takanori Kumagai, Kenichi Ishizawa, Yutaka Miura, Takeshi Shiraishi, Chikayuki Morimoto, Kazuhiro Sakai, Hiroki Omizo, Osamu Yamazaki, Yoshifuru Tamura, Yoshihide Fujigaki, Hiroshi Kawachi, Makoto Kuro-o Makoto, Shunya Uchida, Shigeru Shibata
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1732-1732
- DOI
  10.1038/s41598-018-38389-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-16K09640, KAKENHI-PROJECT-19H03673
[Journal Article] Electrolyte transport in the renal collecting duct and its regulation by the renin–angiotensin–aldosterone system2019
- Author(s)
  Yamazaki Osamu、Ishizawa Kenichi、Hirohama Daigoro、Fujita Toshiro、Shibata Shigeru
- Journal Title
  
  Clinical Science
  
  Volume: 133 Issue: 1 Pages: 75
- DOI
  10.1042/cs20180194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08201, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-17K16097
[Journal Article] A Case of Rheumatoid Arthritis Presenting with Renal Thrombotic Microangiopathy Probably due to a Combination of Chronic Tacrolimus Arteriolopathy and Severe Hypertension2019
- Author(s)
  Honma Fumika、Fujigaki Yoshihide、Nemoto Yoshikazu、Kikuchi Hirotoshi、Nagura Michito、Arai Shigeyuki、Ishizawa Kenichi、Yamazaki Osamu、Tamura Yoshifuru、Kondo Fukuo、Ohashi Ryuji、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  Case Reports in Nephrology
  
  Volume: 2019 Pages: 1-7
- DOI
  10.1155/2019/3923190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09640, KAKENHI-PROJECT-16K04187, KAKENHI-PROJECT-15H05788
[Journal Article] Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study2019
- Author(s)
  Nishimoto Mitsuhiro、Ohtsu Hiroshi、Marumo Takeshi、Kawarazaki Wakako、Ayuzawa Nobuhiro、Ueda Kohei、Hirohama Daigoro、Kawakami-Mori Fumiko、Shibata Shigeru、Nagase Miki、Isshiki Masashi、Oba Shigeyoshi、Shimosawa Tatsuo、Fujita Toshiro
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 4 Pages: 514
- DOI
  10.1038/s41440-018-0201-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06841, KAKENHI-PROJECT-18K12134, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-17K16075, KAKENHI-PROJECT-17K09736, KAKENHI-PROJECT-18K19533
[Journal Article] Role of Pendrin in the Pathophysiology of Aldosterone-Induced Hypertension2019
- Author(s)
  Shibata Shigeru
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 32 Issue: 7 Pages: 607
- DOI
  10.1093/ajh/hpz054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Inhibition of sodium glucose cotransporter 2 attenuates the dysregulation of Kelch-like 3 and NaCl cotransporter in obese diabetic mice2019
- Author(s)
  Ishizawa Kenichi、Wang Qin、Li Jinping、Xu Ning、Nemoto Yoshikazu、Morimoto Chikayuki、Fujii Wataru、Tamura Yoshifuru、Fujigaki Yoshihide、Tsukamoto Kazuhisa、Fujita Toshiro、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 30 Issue: 5 Pages: 782
- DOI
  10.1681/asn.2018070703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-19H03678
[Journal Article] Group I metabotropic glutamate receptor activation induces TRPC6-dependent calcium influx and RhoA activation in cultured human kidney podocytes2019
- Author(s)
  Wang Qin、Wang Derun、Shibata Shigeru、Ji Tianrong、Zhang Lei、Zhang Rui、Yang He、Ma Linlin、Jiao Jundong
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 511 Issue: 2 Pages: 374
- DOI
  10.1016/j.bbrc.2019.02.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor2018
- Author(s)
  Shibata Shigeru、Ishizawa Kenichi、Wang Qin、Xu Ning、Fujita Toshiro、Uchida Shunya、Lifton Richard P.
- Journal Title
  
  Cell Reports
  
  Volume: 24 Issue: 3 Pages: 569
- DOI
  10.1016/j.celrep.2018.06.072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K16097
[Journal Article] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Hirohama D, Ayuzawa N, Ueda K, Nishimoto M, Kawarazaki W, Watanabe A, Shimosawa T, Marumo T, Shibata S, Fujita T
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 29 Issue: 1 Pages: 57
- DOI
  10.1681/asn.2017030243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15466, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-15K19443, KAKENHI-PROJECT-26860546
[Journal Article] Emergence of Smoldering ANCA-associated Glomerulonephritis during the Clinical Course of Mixed Connective Tissue Disease and Sjögren's Syndrome2018
- Author(s)
  Morimoto C, Fujigaki Y, Tamura Y, Ota T, Shibata S, Asako K, Kikuchi H, Kono H, Kondo F, Yamaguchi Y, Uchida S.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 12 Pages: 1757-1762
- DOI
  10.2169/internalmedicine.9844-17
- NAID
  130007397142
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-06-15
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Discontinuation of Hemodialysis in a Patient with Anti-GBM Disease by the Treatment with Corticosteroids and Plasmapheresis despite Several Predictors for Dialysis-Dependence.2017
- Author(s)
  Fujigaki Y, Morimoto C, Iino R, Taniguchi K, Kawamorita Y, Asakawa S, Toyoki D, Miyano S, Fujii W, Ota T, Shibata S, Uchida S.
- Journal Title
  
  Case reports in nephrology
  
  Volume: 2017 Pages: 7143649-7143649
- DOI
  10.1155/2017/7143649
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Mineralocorticoid receptor and NaCl transport mechanisms in the renal distal nephron2017
- Author(s)
  Shigeru Shibata
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Phosphorylation by PKC and PKC regulate the kinase activity and downstream signaling of WNK4.2017
- Author(s)
  Castaneda-Bueno M, Arroyo JP, Zhang J, Puthumana J, Yarborough O, Shibata S, Rojas-Vega L, Gamba G, Rinehart J, Lifton RP
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] A Rare Adult Case with Diffuse Segmental Membranous Glomerulonephritis2017
- Author(s)
  Fujigaki Y, Tamura Y, Shibata S, Kondo F, Iwakura T, Kojima K, Yamaguchi Y, Uchida S.
- Journal Title
  
  Intern. Med.
  
  Volume: 56 Issue: 13 Pages: 1691-1695
- DOI
  10.2169/internalmedicine.56.8298
- NAID
  130006858086
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Open Access
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Unique proximal tubular cell injury and the development of acute kidney injury in adult patients with minimal change nephrotic syndrome2017
- Author(s)
  Fujigaki Y, Tamura Y, Nagura M, Arai S, Ota T, Shibata S, Kondo F, Yamaguchi Y, Uchida S.
- Journal Title
  
  BMC nephrology
  
  Volume: 18 Issue: 1 Pages: 339-339
- DOI
  10.1186/s12882-017-0756-6
- Open Access
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Targeting gene expression to specific cells of kidney tubules in vivo, using adenoviral promoter fragments2017
- Author(s)
  Sumiyo Watanabe , Toru Ogasawara, Yoshifuru Tamura, Taku Saito, Toshiyuki Ikeda, Nobuchika Suzuki, Tatsuo Shimosawa, Shigeru Shibata, Ung-il Chung, Masaomi Nangaku, Shunya Uchida
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 3 Pages: 1-14
- DOI
  10.1371/journal.pone.0168638
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09683, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-26293330
[Journal Article] Hypokalemia and pendrin induction by aldosterone2017
- Author(s)
  Xu N, Hirohama D, Ishizawa K, Chang WX, Shimosawa T, Fujita T, Uchida S, Shibata S.
- Journal Title
  
  Hypertrension
  
  Volume: 69 Pages: 855-862
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats2017
- Author(s)
  Kawamorita Y, Shiraishi T, Tamura Y, Kumagai T, Shibata S, Fujigaki Y, Hosoyamada M, Nakagawa T, Uchida S.
- Journal Title
  
  Physiological reports
  
  Volume: 5 Issue: 15 Pages: e13358-e13358
- DOI
  10.14814/phy2.13358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00871, KAKENHI-PROJECT-17K08605
[Journal Article] Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK42017
- Author(s)
  Castaneda-Bueno M, Arroyo JP, Zhang J, Puthumana J, Yarborough O, Shibata S, Rojas-Vega L, Gamba G, Rinehart J, Lifton RP
- Journal Title
  
  Proc Natl Acd Sci USA.
  
  Volume: 114 Issue: 5 Pages: 879-886
- DOI
  10.1073/pnas.1620315114
- URL
  https://localhost/en/publications/f9e2b914-29bf-474d-9841-9c1431655d6e
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats2017
- Author(s)
  Asakawa S, Shibata S, Morimoto C, Shiraishi T, Nakamura T, Tamura Y, Kumagai T, Hosoyamada M, Uchida S.
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2017 Issue: 1 Pages: 1-14
- DOI
  10.1155/2017/3759153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K08605
[Journal Article] Uric acid in the follow-up determines 30% decline in estimated GFR over 2 years: A propensity score analysis2017
- Author(s)
  Chang WX, Xu N, Kumagai T, Iijima R, Waki K, Yamanaka M, Nagura M, Arai S, Tamura Y, Shibata S, Fujigaki Y, Uchida S.
- Journal Title
  
  Kidney & blood pressure research
  
  Volume: 42 Issue: 6 Pages: 1053
- DOI
  10.1159/000485593
- NAID
  130005859009
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 22017
- Author(s)
  Toyoki D, Shibata S, Kuribayashi-Okuma E, Xu N, Ishizawa K, Hosoyamada M, Uchida S.
- Journal Title
  
  American journal of physiology. Renal physiology.
  
  Volume: 313 Issue: 3 Pages: 826-834
- DOI
  10.1152/ajprenal.00012.2017
- URL
  https://pure.teikyo.jp/en/publications/d06c4a71-34cf-4f10-975e-deddfb7da550
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00871, KAKENHI-PROJECT-17K08605, KAKENHI-PROJECT-15H04837
[Journal Article] Hypokalemia and Pendrin Induction by Aldosterone2017
- Author(s)
  Xu N, Hirohama D, Ishizawa K, Chang WX, Shimosawa T, Fujita T, Uchida S, Shibata S
- Journal Title
  
  Hypertension
  
  Volume: 69 Issue: 5 Pages: 855
- DOI
  10.1161/hypertensionaha.116.08519
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837
[Journal Article] Mineralocorticoid receptor and NaCl transport mechanisms in the renal distal nephron2017
- Author(s)
  Shibata S
- Journal Title
  
  J Endocrinol
  
  Volume: 234 Issue: 1 Pages: 35-47
- DOI
  10.1530/joe-16-0669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837
[Journal Article] Stimulation of V1a receptor increases renal uric acid clearance via urate transporters: Insight into pathogenesis of hypouricemia in SIADH2016
- Author(s)
  Taniguchi K, Tamura Y, Kumagai T, Shibata S, Uchida S.
- Journal Title
  
  Clin Exp Nephrol. 2016 Dec
  
  Volume: 20(6) Pages: 845-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3.2016
- Author(s)
  Ishizawa K, Xu N, Loffing J, Lifton RP, Fujita T, Uchida S, Shibata S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 480 Pages: 745-751
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain.2016
- Author(s)
  Tomioka NH, Tamura Y, Takada T, Shibata S, Suzuki H, Uchida S, Hosoyamada M.
- Journal Title
  
  Fluids Barriers CNS.2016 Dec 12
  
  Volume: 3(1) Pages: 22-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Pathological implications of linear immunoglobulin G staining on the glomerular capillary walls in a case of infection-related glomerulonephritis2016
- Author(s)
  Yoshihide Fujigaki, Yosuke Kawamorita, Hiromi Yamaguchi, Shigeyuki Arai, Yoshifuru Tamura, Tatsuru Ota, Shigeru Shibata, Fukuo Kondo, Yutaka Yamaguchi, Shunya Uchida.
- Journal Title
  
  Pathology International Pathol Int. 2016 Sep
  
  Volume: 66 Issue: 9 Pages: 524
- DOI
  10.1111/pin.12441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 32016
- Author(s)
  Kenichi Ishizawa, Ning Xu, Johannes Loffing, Richard P. Lifton, Toshiro Fujita, Shunya Uchida, Shigeru Shibata.
- Journal Title
  
  Biochem Biophys Res Commun. 2016 Nov
  
  Volume: 480 Issue: 4 Pages: 745
- DOI
  10.1016/j.bbrc.2016.10.127
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00871, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-15H05788
[Journal Article] Context-dependent mechanisms modulating aldosterone signaling in the kidney.2016
- Author(s)
  Shibata S.
- Journal Title
  
  Clin Exp nephrol
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] Proteomics Approach Identifies Factors Associated With the Response to Low-Density Lipoprotein Apheresis Therapy in Patients With Steroid-Resistant Nephrotic Syndrome2016
- Author(s)
  Kuribayashi-Okuma E, Shibata S, et al.
- Journal Title
  
  Ther Apher Dial
  
  Volume: 20 Issue: 2 Pages: 174
- DOI
  10.1111/1744-9987.12356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04837
[Journal Article] The Impact of Normal Range of Serum Phosphorus on the Incidence of End-Stage Renal Disease by A Propensity Score Analysis.2016
- Author(s)
  Chang W-X, Xu N, Kumagai T, Shiraishi T, Kikuyama T, Omizo H, Sakai K, Arai S, Tamura Y, Ota T, Shibata S, Fujigaki Y, Shen Z-Y, Uchida S.
- Journal Title
  
  PLoS ONE. 2016 Apr 28
  
  Volume: 11(4) Pages: 0154469-0154469
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00871
[Journal Article] Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation2014
- Author(s)
  Shibata S et al.
- Journal Title
  
  Proceedings of National Academy of Science USA
  
  Volume: 111 Issue: 43 Pages: 15556
- DOI
  10.1073/pnas.1418342111
- URL
  https://pure.teikyo.jp/en/publications/54f91ce3-d899-4de8-ac87-2dc6a168f38e
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893277
[Presentation] 近位尿細管ナトリウム輸送体 NBCe1 の新規変異体 R881S の機能的解析2023
- Author(s)
  佐藤陽菜，山崎修，森本幾之，新井繁幸，古川泰司，上妻謙，柴田茂
- Organizer
  第66回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-21K08566
[Presentation] Role of KLHL3-S433 phosphorylation in potassium homeostasis in mice2023
- Author(s)
  Kenichi Ishizawa, Ken Kaseda, Daigoro Hirohama, Osamu Yamazaki, Shigeru Shibata
- Organizer
  American Society of Nephrology, Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07683
[Presentation] ナトリウム重炭酸共輸送体 NBCe1の新規変異体R881Sはドミナントネガティブ作用を伴わない膜発現欠損と質量低下を来す2023
- Author(s)
  山崎修、藤井航、佐藤陽菜、古川泰司、上妻謙、藤垣嘉秀、柴田茂
- Organizer
  第45回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-21K08566
[Presentation] A Novel R881S Mutant of Transporter NBCe1 Has Cytosolic Retention and Lacks Dominant Negative Effect2023
- Author(s)
  Osamu Yamazaki, Wataru Fujii, Yoshihide Fujigaki, Shigeru Shibata.
- Organizer
  Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08566
[Presentation] 近位尿細管ナトリウム輸送体NBCe1の新規変異体R881Sの機能的解析2023
- Author(s)
  佐藤　陽菜、山崎　修、藤井　航、古川　泰司、上妻　謙、藤垣　嘉秀、柴田　茂
- Organizer
  第66回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-21K08566
[Presentation] ヒト尿中exosome分画と腎免疫染色におけるユビキチンリガーゼKLHL3リン酸化の検討2022
- Author(s)
  石澤健一, 山崎修, 田村好古, 藤垣嘉秀, 鶴谷悠也, 西川哲男, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] ミネラルコルチコイド受容体関連高血圧を考える　慢性腎臓病の進展とミネラルコルチコイド受容体(MR)2022
- Author(s)
  柴田　茂
- Organizer
  日本内分泌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 腎性低尿酸血症1型モデルマウスにおける運動後急性腎障害のメカニズム2022
- Author(s)
  細山田真, 内田俊也, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 心腎連関における治療戦略のパラダイムシフト～CKD患者におけるCVD抑制～　MR拮抗薬によるアルドステロン関連高血圧への介入2022
- Author(s)
  柴田　茂
- Organizer
  日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] ESA抵抗性におけるセレン欠乏の役割および鉄動態との関連の検討2022
- Author(s)
  安川穂, 新井繁幸, 奈倉倫人, 木戸亮, 浅川信一郎, 広浜大五郎, 山崎修, 田村好古, 藤巻道孝, 小林沙和子, 三牧正和, 児玉浩子, 内田俊也, 藤垣嘉秀, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 慢性腎臓病モデルラットにおけるメリンジョの蛋白尿減少効果2022
- Author(s)
  田村好古, 森本幾之, 仲川孝彦, 内田俊也, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] HIF-PH阻害薬による貧血改善効果における赤血球指数と鉄動態の検討2022
- Author(s)
  新井繁幸, 森本幾之, 浅川信一郎, 奈倉倫人, 山崎修, 田村好古, 藤垣嘉秀, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice2021
- Author(s)
  Daigoro Hirohama, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Wakako Kawarazaki, Wataru Fujii, Shigeyoshi Oba, Shigeru Shibata Takeshi Marumo and Toshiro Fujita
- Organizer
  AHA Hypertension 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 原発性アルドステロン症におけるCl/HCO3輸送体pendrinの検討2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、柴田　茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] Association of serum selenium levels with the response to erythropoiesis-stimulating agents in maintenance hemodialysis patients2021
- Author(s)
  Minoru Yasukawa, Shigeyuki Arai, Michito Nagura, Shinichiro Asakawa, Daigoro Hirohama, Osamu Yamazaki, Yoshifuru Tamura, Hiroko Kodama, Shunya Uchida, Yoshihide Fujigaki, Shigeru Shibata
- Organizer
  ASN Kidney Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 尿中exosome画分のpendrin発現は原発性アルドステロン症患者のアルドステロン・レニン比と相関し、治療により減弱する2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、藤井航、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、柴田　茂
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] PAN腎症モデルにおけるエネルギー代謝異常とATP感受性カリウムチャネルの病的役割の検討2021
- Author(s)
  山中仁樹、田村好古、内田俊也、柴田　茂
- Organizer
  第64回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 原発性アルドステロン症におけるCl/HCO3輸送体pendrinの検討2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、鶴谷悠也、西川哲男、柴田　茂
- Organizer
  第64回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 血液透析患者のESA反応性におけるセレンの役割と鉄動態との関連2021
- Author(s)
  安川穂、新井繁幸、奈倉倫人、田村好古、浅川信一郎、広浜大五郎、山崎　修、田村好古、三牧正和、児玉浩子、木戸亮、藤巻道孝、小林沙和子、内田俊也、藤垣嘉秀、柴田　茂
- Organizer
  第64回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] A novel I551F variant of Na+/HCO3- cotransporter NBCe1 shows reduced cell surface expression and may exert a dominant negative activity2021
- Author(s)
  Osamu Yamazaki, Maho Yamashita, Tadashi Yoshida, Junichi Hirahashi, Matsuhiko Hayashi Shigeru Shibata
- Organizer
  ASN Kidney Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism2021
- Author(s)
  Fumika Ochiai-Homma, Emiko Kuribayashi-Okuma, Yuya Tsurutani, Kenichi Ishizawa, Kohei Odajima, Mika Kawagoe, Yoshihiro Tomomitsu, Masataka Murakawa, Shinichiro Asakawa, Daigoro Hirohama, Michito Nagura, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Yoshihide Fujigaki, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  ASN Kidney Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 血圧・電解質調節に及ぼす集合管間在細胞の役割2021
- Author(s)
  柴田　茂
- Organizer
  第43回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 腎臓内シグナル伝達系、慢性腎臓病と高血圧2021
- Author(s)
  柴田　茂
- Organizer
  第43回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 高血圧の成因 Up date　MR拮抗薬と高血圧関連疾患2020
- Author(s)
  柴田　茂
- Organizer
  第63回日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pre- and post-treatment analysis of pendrin in the urinary exosome in primary aldosteronism2020
- Author(s)
  Fumika Ochiai, Emiko Kuribayashi-Okuma, Kenichi Ishizawa, Yuya Tsurutani, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  AHA Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] MR拮抗薬と高血圧関連疾患2020
- Author(s)
  柴田　茂
- Organizer
  日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Pre- and post-treatment analysis of pendrin in the urinary exosome in primary aldosteronism2020
- Author(s)
  Fumika Ochiai, Emiko Kuribayashi-Okuma, Kenichi Ishizawa, Yuya Tsurutani, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  AHA Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] ゼロから学ぶミネラルコルチコイド受容体(MR)2020
- Author(s)
  柴田　茂
- Organizer
  第50回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] ミネラルコルチコイド受容体と高血圧：最近の話題2020
- Author(s)
  柴田　茂
- Organizer
  第2回ミネラルコルチコイド受容体関連疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] febuxostatは高尿酸血症合併CKDモデルにおいて酸化ストレス負荷を軽減し、腎障害および心肥大を抑制する2020
- Author(s)
  大溝啓揮、田村好古、森本幾之、浅川信一郎、上野雅樹、早間悠人、内田俊也、藤垣嘉秀、柴田　茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 新たな糖尿病性腎臓病モデルの開発とミネラルコルチコイド受容体の関与の解明2020
- Author(s)
  広浜大五郎、西本光宏、鮎澤信宏、河原崎和歌子、大庭成喜、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  高血圧関連疾患学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] MR拮抗薬と高血圧関連疾患2020
- Author(s)
  柴田　茂
- Organizer
  2020年日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] 食塩・カリウム調節と原発性アルドステロン症2019
- Author(s)
  柴田茂
- Organizer
  第13回ホルモン研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 血圧調節と腎臓2019
- Author(s)
  柴田茂
- Organizer
  第12回熊本腎と電解質代謝を考える会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Role of vasopressin V2 receptor signaling in NKCC2 regulation in diabetes mellitus・American Society of Nephrology Kidney Week 20192019
- Author(s)
  Kazuhiro Sakai, Osamu Yamazaki, Kenichi Ishizawa, Yoshikazu Nemoto, Shinichiro Asakawa, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Yoshihide Fujigaki, Shigeru Shibata
- Organizer
  American Society of Nephrology Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] 尿細管の機能を統合的に理解する　～基礎から最新の知見まで～2019
- Author(s)
  柴田　茂
- Organizer
  2019年日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] Aldosterone paradox: role of pendrin and NCC2019
- Author(s)
  Shigeru Shibata
- Organizer
  APCH Satellite Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 慢性腎臓病と尿酸2019
- Author(s)
  柴田茂
- Organizer
  第52回日本痛風・核酸代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 血液透析患者に対する低カリウム野菜の有用性について～アンケート調査と臨床試験の結果から2019
- Author(s)
  内田俊也、奈倉倫人、秋山留美、柴田茂
- Organizer
  第４回全国低カリウム野菜フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-16K00871
[Presentation] 尿細管の機能を統合的に理解する　基礎から最新の知見まで2019
- Author(s)
  柴田茂
- Organizer
  第62回日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 高血圧成因の新しい話題(RAAS、自己免疫、酸化ストレス、塩分、パラクライン等)　翻訳後修飾による血圧制御と高血圧2019
- Author(s)
  柴田茂
- Organizer
  第62回日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] MR and salt2019
- Author(s)
  Shigeru Shibata
- Organizer
  ISARSH2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎臓におけるアルドステロンシグナルの修飾機構2019
- Author(s)
  柴田茂
- Organizer
  第20回　腎セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Disturbed phosphate metabolism facilitates kidney damage in Dahl salt-sensitive hypertensive rats2019
- Author(s)
  Qin Wang, Kenichi Ishizawa, Yoshikazu Nemoto, Yutaka Miura, Jinping Li, Makoto Kuro-o, Shigeru Shibata
- Organizer
  American Society of Nephrology Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] 25(OH)D3 alone stimulates expression of 1,25(OH)2D3-responsive genes, Calbindin-D9K and Megalin, in mpkDCT cells where Cyp27b1 gene was deleted by CRISPR-Cas92019
- Author(s)
  Takahiro Kikuyama, Takao Susa, Mimi Tamamori-Adachi, Masayoshi Iizuka, Shunya Uchida, Tomoki Okazaki, Shigeru Shibata
- Organizer
  American Society of Nephrology Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] 食塩感受性高血圧における腎臓の役割：これまでの研究と最新の知見2018
- Author(s)
  柴田　茂
- Organizer
  第41回日本高血圧学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Dysregulation of the ubiquitin ligase component kelch-like 3 causes Na-Cl cotransporter activation and salt retention in obese diabetic mice2018
- Author(s)
  Kenichi Ishizawa, Qin Wang, Jinping Li, Ning Xu, Yoshikazu Nemoto, Chikayuki Morimoto, Toshiro Fujita, Shunya Uchida, Shigeru Shibata
- Organizer
  ASN Kidney Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Changes in extracellular potassium levels modulate the function of ubiquitin ligase Kelch-like 32018
- Author(s)
  Jinping Li, Wataru Fujii, Ken-ichi Ishizawa, Qin Wang, Ning Xu, Yoshihide Fujigaki, Shunya Uchida, Shigeru Shibata
- Organizer
  International Society of Hypertension 2018
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018
- Author(s)
  広浜大五郎, 鮎澤信宏, 西本光宏, 河原崎和歌子, 下澤達雄, 丸茂丈史, 柴田茂, 藤田敏郎
- Organizer
  第41回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第22回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018
- Author(s)
  広浜大五郎, 鮎澤信宏, 西本光宏, 河原崎和歌子, 下澤達雄, 丸茂丈史, 柴田茂, 藤田敏郎
- Organizer
  第54回高血圧関連疾患学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 食塩感受性高血圧における腎臓の役割：これまでの研究と最新の知見2018
- Author(s)
  柴田　茂
- Organizer
  第41回日本高血圧学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017
- Author(s)
  広浜大五郎、柴田茂、上田浩平、鮎澤信宏、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017
- Author(s)
  Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
- Organizer
  American Society of Nephrology Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Aldosterone and hypertension: role of mineralocorticoid receptor-dependent and potassium-dependent effects2017
- Author(s)
  Shigeru Shibata
- Organizer
  AHA Joint Hypertension Scientific Sessions 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] 腎pendrinの発現機構と血圧調節における役割の解明2017
- Author(s)
  広浜大五郎、鮎澤信宏、上田浩平、西本光宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、柴田茂、藤田敏郎
- Organizer
  第21回心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016
- Author(s)
  広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
- Organizer
  第59回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Uncovering pathways downstream of angiotensin II signaling in the distal nephron of the kidney.2016
- Author(s)
  Shigeru Shibata
- Organizer
  Gordon Research Conference
- Place of Presentation
  Ciocco, Italy
- Year and Date
  2016-03-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] 腎臓遠位ネフロンにおける鉱質コルチコイド受容体シグナルの制御機構2016
- Author(s)
  柴田茂
- Organizer
  第24回日本ステロイドホルモン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] 腎臓におけるアルドステロンシグナルの修飾メカニズム2016
- Author(s)
  柴田茂
- Organizer
  第17回日本内分泌学会関東甲信越支部
- Invited
- Data Source
  KAKENHI-PROJECT-15H05788
[Presentation] Phosphorylation-dependent regulation of the MR in intercalated cells.2015
- Author(s)
  Shigeru Shibata
- Organizer
  8th International Symposium "Aldosterone, MR, and Salt- What's new?"
- Place of Presentation
  Zermatt, Switzerland
- Year and Date
  2015-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-26893277
[Presentation] 腎臓における体液調節機構と食塩感受性高血圧の病態の研究2015
- Author(s)
  柴田　茂
- Organizer
  第38回日本高血圧学会学術集会
- Place of Presentation
  ひめぎんホール (愛媛県松山市)
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] 腎臓におけるミネラルコルチコイド受容体の活性化機構2015
- Author(s)
  柴田　茂
- Organizer
  第58回　日本腎臓学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-26893277
[Presentation] 腎臓におけるミネラロコルチコイド受容体の制御機構2015
- Author(s)
  柴田　茂
- Organizer
  第58回日本腎臓学会学術集会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H04837
[Presentation] 食塩、アルドステロンと高血圧2014
- Author(s)
  柴田　茂
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26893277
[Presentation] 翻訳後修飾による体液調節機構と高血圧診療における意義2014
- Author(s)
  柴田　茂
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26893277

1. 石澤健一 (10772684)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. FUJITA Toshiro (10114125)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. 広浜大五郎 (20749353)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. Uchida Shunya (50151882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. Yamazaki Osamu (80757229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. 河原崎和歌子 (50424594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. 鮎澤信宏 (50459517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. 丸茂丈史 (70265817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
9. 大庭成喜 (80361492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 下澤達雄 (90231365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
11. 西本光宏 (90646572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
12. 上田浩平 (80735697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. 森典子 (80431857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 岡崎具樹 (60203973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 藤垣嘉秀 (20283351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 諏佐崇生 (20445852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 田村好古 (10459315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. 月田早智子 (00188517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 高地雄太 (60415156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 藤井航 (90786039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Lifton Richard P

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

SHIBATA SHIGERU 柴田 茂

Shibata Shigeru 柴田 茂

柴田 茂 シバタ シゲル

Research Projects

Research Products

Co-Researchers

赤血球・血管内皮・腎尿細管の連関によるカリウム制御機構の解明とヒトへの応用Principal Investigator

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臓器連関によるカリウム調節の分子基盤解明と"gut factor"の探索

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Sodium-bicarbonate cotransporter NBCe1 affects hypertension and diabetes via sodium reabsorption.

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Regulation of nuclear receptor through autophagy-related proteins and other mechanismsPrincipal Investigator

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Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseasesPrincipal Investigator

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Satisfaction and usefulness of low potassium vegetables for patients with chronic kidney disease

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生活習慣病の高血圧／臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索

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Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseasesPrincipal Investigator

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Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunction

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翻訳後修飾による細胞選択的な鉱質コルチコイド受容体制御系の全容解明Principal Investigator

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慢性腎臓病進展におけるRac-MR経路の関与とRac1阻害薬の有用性Principal Investigator

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[Book] Hypertension: A Companion to Braunwald's Heart Disease, 3rd Edition, Edited by George L. Bakris、Matthew Sorrentino Chapter 24 “Renin Angiotensin Aldosterone System Blockers”2017

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Data Source

[Book] Bakris: Hypertension, 3e2016

Author(s)

Publisher

SHIBATA SHIGERU 柴田茂

Shibata Shigeru 柴田茂

柴田茂シバタシゲル