FUJIWARA Hiromi 藤原大美

… Alternative Names

藤原広美フジワラヒロミ

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Researcher Number	70116094
Other IDs
Affiliation (based on the past Project Information) *help	2002: 大阪大学, 医学系研究科, 助教授 2001: 大阪大学, 医学研究科, 助教授 1999 – 2000: 大阪大学, 医学系研究科, 助教授 1986 – 1998: 大阪大学, 医学部, 助教授 1996: 北海道大学, バイオメディカル教育センター, 助教授 … More 1995: 大阪大学, バイオメディカル教育センター, 助教授 1995: 大阪大学, 医学部・附属バイオメディカル教育研究センター, 助教授 1994: 大阪大学, 医学部附属バイオメディカル教育研究センター, 助教授 1993: 大阪大学, 医学部・附属バイオメディカル教育研究センター, 助教授 1989: 大阪大学, 医学部・バイオメディカル教育研究センター, 助教授 1988: 大阪大, 医学部, 助教授 1988: 大阪大学, 医学部バイオメディカル教育研究センター腫瘍発, 助教授 1987: 大阪大学, 医学部附属・バイオメディカル研究教育センター, 助教授 1986: 大阪大学, 医学部・癌研・腫瘍発生学部門, 助教授 1986: Osaka Univ. Med. Sch., Inst. for Cancer Res., 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Immunology / Functional basic dentistry / Biological Sciences Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 抗原提示細胞 / 免疫寛容 / ヘルパーT細胞 / helper T cells / CD28分子 / DST / 移植免疫 / インターロイキン-12 / T-APC相互作用 / CD40 ligand … More / CD40 / インターロイキン12 / interleukin-12 / costimulation / IL-2レセプター / IL-2 / co-stimulatory signal / 情報伝達 / immunologic tolerance / Transplantation immunity / asialogly coprotein receptor / ヘルパー型T細胞 / clonal deletion / major histocompatibility complex antigens / antigen-presenting cells / delayed-type hypersensitivity / Lyt- <1^+> <2^-> T cells / 主要組適合抗原 / 遅延型過敏症反応 / Lyt-【1^+】【2^-】T細胞 / interferon-gamma / signal transduction / interleukin-12 receptor / T cell actiration / T cell / T細胞増殖 / インターロイキン-12産生 / インターフェロン-γ / インターロイキン-12レセプター / T細胞 / immunosuppresive drugs / transplantation immunology / tolerance / 拒絶反応 / アロ抗原反応性T細胞 / 免疫抑制剤 / T cell growth factor / Thymic selection / T cell repertoire / Iutrathymic T cell proliferation Hifferentiation / Thymic stromal cells / T細胞レパ-トリ-形成 / 胸腺細胞の分化成熟 / thymus selection / T細胞増殖因子 / thymic selection / T細胞レパ-トリ- / 胸腺細胞分化・増殖 / 胸腺ストロ-マ細胞 / rho family GTPase / Antigen-presenting cell / cell-cell interaction / raft / CD 28 / T cell receptor / 遺伝子発現 / 転写因子 / MAPキシナーゼ / インターフエロン / インターロイキン-18 / interferon-2 / B7分子群 … More Except Principal Investigator サイトカイン / がん遺伝子 / 抗原提示細胞 / がん抗原 / 腫瘍抗原 / 抗腫瘍免疫 / キラーT細胞 / 免疫抑制 / 腫瘍抗原認識機構 / LAK細胞 / 腫瘍免疫 / インターロイキン12 / IL-2レセプター / Co-stimulation / 癌 / IL-12 / 生体工学 / サイトカインネットワーク / T細胞レセプター / 担癌状態 / ILー2レセプター / パーフォリン / NK / レトロウイルス / エフェクター細胞 / サイトカインレセプター / 分化抗原 / Lymphokine / Immune Desponse / T Cell Growth / Tumor Antigen / Tumor Supressor Gene / Tumor Promoter / Viral Oncogene / Oncogene / リンフォカイン / 免疫応答 / T細胞の増殖 / がん抑制遺伝子 / 発がんプロモ-タ- / ウイルス発がん / Lyt-2^+細胞 / L3L4^+細胞 / 腫瘍拒絶抗原 / 自然免疫 / HTLV-1 / 自己免疫 / セリンエステラーゼ / 慢性B白血病細胞 / NK骨髄腫細胞 / CTL / 細胞がん化 / マクロファージ活性化機構 / マクロファージハイブリドーマ / 抗原提示細胞(APC) / Lyt-2^+T細胞 / L3T4^+T細胞 / 腫瘍関連移植抗原 / CD2 / TATA / Oncgene / GVHD / MRL / 腫瘍エスケープ機構 / 分化・脱分極化 / ヘルパーT細胞 / T細胞因子:マクロファージ / 腫瘍特異免疫療法 / Muramyl dipeptide ハプテン / T-T細胞間相互作用 / 補体 / 腫瘍内浸潤細胞 / T領域組織球 / 細胞障害性T細胞分化誘導因子 / T-T細胞相互作用 / 細胞電気泳動 / 癌免疫増強 / 癌薬物療法 / キラーT細胞活性化因子 / IL-2 / リンホトキシン / IL4 / IL3 / IL2 / T細胞因子 / リンホカイン / 遅延型T細胞 / NK細胞 / マクロファージ / インテグリン / ケモカインレセプター / STAT4 / IFN-γ / 担癌 / TAK-779 / ケモカイン / CXCR3 / CCR5 / 接着 / 浸潤 / Th1 / 悪液質 / NF-IL 6 / STAT3 / 増殖シグナル / CTLA4 / 酸化ストレス / CD45フォスファターゼ / 遺伝子欠損マウス / Srcファミリーキナーゼ / TCR-CD_3複合体 / カタラーゼ / インターロイキン5 / ヘルパーTリンパ球 / インターロイキン6 / 癌悪液質 / 腫瘍 / Jak3欠損マウス / セリン・スレオニンキナーゼ / CD3結合分子 / シグナル伝達 / 遺伝子発現 / 免疫不全 / ペプチドモチーフ / クラスIMHC / T細胞レパトア / TIL / 補助シグナル / T細胞エピトープ / MHCペプチド / 免疫寛容 / トレランス / 養子免疫療法 / NKT細胞 / ドレランス / がん免疫 / Co-stimulator / Jak / Syk / CD28 / CD45 / HS1 / TCR構造異常 / T細胞活性化 / 産生制御 / 癌病態 / TGF-β / CD4^+T細胞 / 抗腫瘍T細胞 / TGFーβ / CD4^+細胞 / ヘルパ-T細胞 / TGFーβ(transforming growth factorーβ) / 担癌宿生 / チロシンリン酸化 / 抗レセプタ-抗体 / 異常増殖 / T細胞 / エフェクタ-細胞 / シグナル伝達機構 / サイトカインレセプタ- / がん関連抗原 / 内在性レトロウィルス / 熱タンパク / アンティセンス / トランスフレ-ス遺伝子 / 腫瘍抵抗性 / 腫瘍抗原提示機構 / 抗原処理機構 / ヘルパ-T細胞腫瘍 / CD4 / HVG / B白血病細胞 / 骨髄腫細胞 / T細胞抗原受容体 / ナチュラルキラー細胞 / 細胞傷害性T細胞 / Antisense RNA / 糖転移酵素 Less

Research Projects
(42 results)
Co-Researchers
(92 People)

T細胞の副刺激情報伝達の解析と情報変換によるアポトーシス誘導Principal Investigator
- Principal Investigator
  
  藤原大美
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
腫瘍退縮に至る担がん宿主T細胞の腫瘍局所浸潤の分子機構
- Principal Investigator
  
  濱岡利之
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
IL-12の情報伝達とTh2サイトカインによる制御機構Principal Investigator
- Principal Investigator
  
  藤原大美
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
がん免疫寛容のメカニズムとその制御
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
サイトカインの分子制御による癌免疫治療
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
インターロイキン12の産生及び活性調節による免疫制御Principal Investigator
- Principal Investigator
  
  藤原大美
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
The role of interleukin-12 (IL-12) in T cell activation and IL-12 receptor-mediated signalingPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hiromi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator
- Principal Investigator
  
  藤原広美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator
- Principal Investigator
  
  藤原大美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
腫瘍抗原認識の分子免疫学的解析と担癌個体のサイトカインカスケード是正の研究
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator
- Principal Investigator
  
  藤原大美
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Tolerance induction of alloreactive T cells and regulation of graft rejectionPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hiromi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
腫瘍抗原認識の分子免疫学的解析と相癌個体のサイトカインカスケ-ド是正の研究
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
がん抗原の発現調節と免疫系による認識
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
エフェクタ-細胞の機能分化:サイトカインとそのレセプタ-系を中心にしたアプロ-チ
- Principal Investigator
  
  高津聖志
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
腫瘍抗原認識の分子免疫学的解析と担癌個体のサイトカインカスケ-ド是正の研究
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
エフェクター細胞の機能分化;サイトカインとそのレセプター系を中心としたアプローチ
- Principal Investigator
  
  高津聖志
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
宿主側からみた腫瘍増殖機序の分子免疫学的解析
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
腫瘍免疫の抗原認識機構の解析と人為的制御
- Principal Investigator
  
  HAMAOKA Toshiyuki
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Analyses of T Cell Proliferation/Differentiation and Repertoire Selection in the thy UsusPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hiromi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University Medical School
がん抗原の発現調節と免疫系による認識
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
がん抗原の発現調節と免疫系による認識
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
エフェクター細胞の機能分化:サイトカインとそのレセプター系を中心にしたアプローチ
- Principal Investigator
  
  高津聖志
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
腫瘍免疫の抗原認識機構の解析と人為的制御
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Information Exchange on Cancer Research with North American Countries
- Principal Investigator
  
  YAMAGUCHI Nobuo, 河井貞明
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The Institute of Medical Science, The University of Tokyo
宿主側から見た腫瘍増殖機序の分子免疫学的解析
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
腫瘍免疫の抗原認識機構の解析と人為的制御
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Tolerance induction of alloantigen-reactive T cells and analysis of its immunologic and cell-biologic mechanismsPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Hiromi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
T細胞因子による抗腫瘍免疫の調節機構に関する研究
- Principal Investigator
  
  熊谷勝男
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
腫瘍関連移植抗原に対する免疫応答の細胞性及び分子機構の解析とその応用
- Principal Investigator
  
  浜岡利之
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
T細胞因子による抗腫瘍免疫の調節機構に関する研究
- Principal Investigator
  
  熊谷勝男
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
宿主側から見た腫瘍増殖機序の分子免疫学的解析
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
腫瘍抗原の発現と免疫系の認識に関する分子免疫学的解析
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
腫瘍抗原の発現と免疫系の認識に関する分子免疫学的解析
- Principal Investigator
  
  谷口克
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University
Studies on the analysis of antigen recognition mechanisms of Lyt- <1^+> <2^-> T cells mediating in vivo cell-mediated immunity and the regulation of induction of these cells.Principal Investigator
- Principal Investigator
  
  FUJIWARA Hiromi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
癌薬物療法におけるエフェクター・サプレッサーバランスのバイオダイナミクス
- Principal Investigator
  
  新田和男
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

1. HAMAOKA Toshiyuki (60028529)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
2. SUGAMURA Kazuo (20117360)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. 谷口克 (80110310)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. 熊谷勝男 (00005018)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. 栗林景容 (10064578)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. 奥村康 (50009700)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. 佐藤昇志 (50158937)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. 松島綱治 (50222427)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. 審良静男 (50192919)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
11. 細川真澄男 (20001901)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
12. 竹森利忠 (60114295)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. 松岡雄治 (70078773)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. 高津聖志 (10107055)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. 吉永秀 (90040196)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. 平野俊夫 (40136718)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. 吉田孝人 (90041847)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
18. 垣生園子 (30051618)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
19. 白井俊一 (30115860)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
20. 西村泰治 (10156119)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
21. 横田崇 (50134622)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
22. 向田直史 (30182067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
23. 斉藤隆 (50205655)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
24. 南康博 (70229772)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
25. 岸原健二 (80214774)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
26. 高橋秀実 (40221361)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
27. KAWAI Sadaaki (70107423)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
28. 森脇和郎 (50000229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
29. 山崎正利 (00107393)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
30. 村松繁 (30025291)

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FUJIWARA Hiromi 藤原 大美

藤原 広美 フジワラ ヒロミ

Research Projects

Co-Researchers

T細胞の副刺激情報伝達の解析と情報変換によるアポトーシス誘導Principal Investigator

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IL-12の情報伝達とTh2サイトカインによる制御機構Principal Investigator

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インターロイキン12の産生及び活性調節による免疫制御Principal Investigator

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The role of interleukin-12 (IL-12) in T cell activation and IL-12 receptor-mediated signalingPrincipal Investigator

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T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

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T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

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T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

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Project Period (FY)

FUJIWARA Hiromi 藤原大美

藤原広美フジワラヒロミ