Yan Kunimasa 楊國昌

… Alternative Names

YAN KUNIMASA 楊國昌

YAN Kunimasa 楊國昌

楊国昌ヤンクニマサ

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Researcher Number	70255389
Other IDs
External Links
Affiliation (Current)	2025: 杏林大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2025: 杏林大学, 医学部, 特任教授 2021: 杏林大学, 医学部, 客員教授 2019 – 2020: 杏林大学, 医学部, 教授 2015 – 2017: 杏林大学, 医学部, 教授 2009 – 2012: Kyorin University, 医学部, 教授 … More 2007: Kyorin University, Faculty of Medicine, Associate Professor 2006: 杏林大学, 医学部, 助教授 2002 – 2004: 杏林大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine / Pediatrics / Pediatrics Except Principal Investigator Pediatrics / Pediatrics / General pharmacology
Keywords	Principal Investigator ポドサイト / ネフローゼ / 糸球体硬化 / zebrafish / mTOR / 創薬 / ケモカイン / キナーゼ / プロテオーム / メタボローム … More / NEP25 / アドリアマイシン / 質量解析 / crescentic glomerulonephritis / podocyte / amino acid transporter / 輸送体 / アミノ酸 / 半月体形成性腎炎 / アミノ酸輸送体 / missense mutant / protein transport / slit membrane / nephrin / podocin / 細胞内蛋白輸送 / Nephrin / Podocin / 蛋白細胞内輸送 / ミスセンス変異 / 蛋白輸送 / スリット膜 / ネフリン / ポドシン / 糸球体 / 精巣 / ステロイド / 細胞内骨格 / 胸腺 / T細胞 / PAK1 / Dlc8 / Glcci1 / アポトーシス / Ｔ細胞 / 糖質ステロイド … More Except Principal Investigator BCH / LAT1 / hematopoietic stem cells / cell lines / acute myeloid leukemia / acute lymphocytic leukemia / bone marrow cells / inhibitor / インフォームドコンセント / 倫理委員会 / 抗LAT1モノクローナル抗体 / 抗原特異性 / ゼラチンカプセル / 細胞内局在 / ウェスタンブロット / 凍結切片 / LD50 / MTTアッセイ / アミノ酸トランスポーター / 4F2hc / 小児白血病 / 造血幹細胞 / 白血病細胞株 / 急性骨髄性白血病 / 急性リンパ球性白血病 / 骨髄細胞 / インヒビター / ネフローゼ / ユビキチン / 泌尿器学 / 小児腎 / 蛋白質 / 遺伝子 / 薬理学 / 腎尿細管 / 高尿酸血症 / 痛風 / 尿酸 / トランスポーター Less

Identification of Signal Pathways Inducing Glomerulosclerosis in Refractory Nephrotic SyndromePrincipal Investigator
- Principal Investigator
  
  楊國昌
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyorin University
Integrated omics analysis for drug discovery of intractable nephrotic syndromePrincipal Investigator
- Principal Investigator
  
  YAN KUNIMASA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyorin University
Integration of proteomics and metabolomics for drug discovery based on a search for the pathophysiology in glomerulosclerosisPrincipal Investigator
- Principal Investigator
  
  YAN KUNIMASA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Role of Ubiquitin specific protease 40 in Glomerulus
- Principal Investigator
  
  NISHIBORI Yukino
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University
New drug development for hyperuricemia targeting novel urate efflux transporter URATv1
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
  Kyorin University
Functional analysis of glucocorticoid induced transcript 1(GLCCI1)Principal Investigator
- Principal Investigator
  
  YAN Kunimasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University
Role of System LAmino Acid Transporter in Podocyte Cell BiologyPrincipal Investigator
- Principal Investigator
  
  YAN Kunimasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Protein analysis of steroid resistant congenital nephrotic syndrome gene: podocinPrincipal Investigator
- Principal Investigator
  
  YAN Kunimasa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University
Analysis of Expression of LAT1 in Childhood Leukemia and Effect of Inhibitors on Proliferation Inhibition
- Principal Investigator
  
  BESSHO Fumio
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University

All 2015 2012 2010 2007 2005 2004 2003

All Journal Article Presentation

[Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2010
- Author(s)
  Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 45 Pages: 35123-35132
- DOI
  10.1074/jbc.m110.121301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Protein Characterization of Na+-Independent System L Amino Acid Transporter 3 in Mice : A Potential Role in Supply of Branched-Chain Amino Acids under Nutrient Starvation2007
- Author(s)
  Fukuhara, D., Kanai, Y., Chairoungdua, A., Babu, E., Bessho, F., Kawano, T., Akimoto, Y., Endou, H., Yan, K
- Journal Title
  
  Am J Pathol 170(3)
  
  Pages: 888-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590901
[Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawakami H, Shibasaki T, Endou H
- Journal Title
  
  J Pharmacol Sci 97
  
  Pages: 234-241
- NAID
  10025726124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Characterization of the interactions of the nephrin intracellular domain.2005
- Author(s)
  Liu XL, Kilpelainen P, Hellman U, Sun Y, Wartiovaara J, Morgunova E, Pikkarainen T, Yan K, Jonsson AP, Tryggvason K
- Journal Title
  
  FEBS J 272
  
  Pages: 228-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] ネフリンの糖鎖異常2004
- Author(s)
  楊國昌, 他
- Journal Title
  
  Annual Review腎臓 1
  
  Pages: 27-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnoodi J, Yan K
- Journal Title
  
  Kidney Int 66
  
  Pages: 1755-1765
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Defective trafficking of nephrin missense mutants rescued by a chemical chaperone.2004
- Author(s)
  Liu XL, Done SC, Yan K, Kilpelainen P, Pikkarainen T, Tryggvason K
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 1731-1738
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Variable expression of podocyte-related markers in the glomeruloid bodies in Wilms tumor.2003
- Author(s)
  Kanemoto K, Takahashi S, Shu Y, Usui J, Tomari S, Yan K, Hamazaki Y, Nagata M
- Journal Title
  
  Pathol Int 53
  
  Pages: 596-601
- NAID
  10012439208
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] 後天性腎疾患におけるネフリンの役割2003
- Author(s)
  楊國昌
- Journal Title
  
  腎と透析 55
  
  Pages: 771-776
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Presentation] プロテオーム解析による糸球体硬化の病態解明2015
- Author(s)
  西堀由紀野，高橋昌兵，福冨俊之，秋元義弘，楊國昌
- Organizer
  第50回日本小児腎臓病学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-15K09270
[Presentation] (Department o Pediatrics,Anatomy, Pharmacology,Lab Membrane Biochemistry and Biophysics Graduate School of Biostudies, Kyoto University)Role of ubiquitin specific protease 40(USP40) in glomerular development.2012
- Author(s)
  Takagi H, Nishibori Y, Kiuchi Z, Ito Y, Kudo A, Akimoto Y, Kimura T, Takematsu H, Yan K
- Organizer
  The 4thEMBO meeting 2012
- Place of Presentation
  Nice
- Data Source
  KAKENHI-PROJECT-22591191
[Presentation] (杏林大・医・小児科・薬理学・解剖):糸球体の発生に置けるユビキチン特異的プロテアーゼ40(USP40)の役割2012
- Author(s)
  高木永, 西堀由紀野, 木村徹,宮東昭彦, 楊國昌
- Organizer
  第47回日本小児腎臓病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591191

1. AKIMOTO Yoshihiro (60184115)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. KANAI Yoshikatsu (60204533)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. FUKUTOMI Toshiyuki (30439187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. ISHIGAKI Yasuhito (20232275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHIBORI Yukino (70407021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. ENDOU Hitoshi (20101115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. ANZAI Naohiko (70276054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. UCHIDA Kohsuke (30168695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KOJIMA Shuichi (60178267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. DOMAE Mariko (20285878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HAYASHI Keitaro (10323106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KIMURA Toru (30433725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. MIURA Daisaku (60510873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWAHARA Katsumasa (70134525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. BESSHO Fumio (40010285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOSHINO Hiroshi (30333032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HOSOYAMADA Makoto (00291659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. KUDO Akihiko (80255398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. OKUNO YASUSHI (20283666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MATSUSAKA TAIJI (50317749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 清水章 (00256942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 田中絵里子 (80439827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 木内善太郎 (00756249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 片山鑑 (90742247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TSUKADA Ai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. WEMPE Michael F.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. AMMONPATUMRAT Sirirat

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. THAMMAPRATIP Thanapol

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 宮嶋伸一郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yan Kunimasa 楊 國昌

YAN KUNIMASA 楊 國昌

YAN Kunimasa 楊 國昌

楊国 昌 ヤンクニ マサ

Research Projects

Research Products

Co-Researchers

Identification of Signal Pathways Inducing Glomerulosclerosis in Refractory Nephrotic SyndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrated omics analysis for drug discovery of intractable nephrotic syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integration of proteomics and metabolomics for drug discovery based on a search for the pathophysiology in glomerulosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Ubiquitin specific protease 40 in Glomerulus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New drug development for hyperuricemia targeting novel urate efflux transporter URATv1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of glucocorticoid induced transcript 1(GLCCI1)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of System LAmino Acid Transporter in Podocyte Cell BiologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein analysis of steroid resistant congenital nephrotic syndrome gene: podocinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Expression of LAT1 in Childhood Leukemia and Effect of Inhibitors on Proliferation Inhibition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein Characterization of Na+-Independent System L Amino Acid Transporter 3 in Mice : A Potential Role in Supply of Branched-Chain Amino Acids under Nutrient Starvation2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Characterization of the interactions of the nephrin intracellular domain.2005

Author(s)

Journal Title

Yan Kunimasa 楊國昌

YAN KUNIMASA 楊國昌

YAN Kunimasa 楊國昌

楊国昌ヤンクニマサ

[Presentation] (杏林大・医・小児科・薬理学・解剖):糸球体の発生に置けるユビキチン特異的プロテアーゼ40(USP40)の役割2012