OTAGIRI Masaki 小田切優樹

Researcher Number	80120145
Other IDs
External Links
Affiliation (Current)	2025: 崇城大学, 薬学部, 特任教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 崇城大学, 薬学部, 特任教授 2009 – 2017: Sojo University, 薬学部, 教授 2007 – 2008: Kumamoto University, Faculty of Medical and Pharmaceutical Sciences, Professor 2006: 熊本大学, 大学院医学薬学研究部, 教授 2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 教授 1994 – 2002: 熊本大学, 薬学部, 教授 1990 – 1991: 熊本大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Medical pharmacy / Physical pharmacy / Biological pharmacy / Applied pharmacology / 応用薬理学・医療系薬学 / Basic Section 47060:Clinical pharmacy-related / 医薬分子機能学 Except Principal Investigator Medical pharmacy / Applied pharmacology / Basic Section 47060:Clinical pharmacy-related / Physical pharmacy / General pharmacology / Drug development chemistry
Keywords	Principal Investigator アルブミン / ヒト血清アルブミン / 変異体 / 遺伝子組換え技術 / 抗酸化能 / 体内動態 / Blood preparation / Functional evaluation / Artificial blood / Molecular design … More / Site-directed mutagenesis / Albumin preparation / 人工血液 / 血液製剤 / アルブミン製剤 / 血清アルブミン / drug binding site / 微環境解析 / 薬物結合サイト / リポソーム / 肺障害 / Pichia酵母 / 機能性アルブミン / 一酸化窒素 / 担体 / 薬物結合部位 / 薬物 / 腎障害 / 低分子抗体 / 多機能性アルブミン / 低分子抗体医薬 / 低分子抗体融合体 / 融合技術 / 抗腫瘍効果 / 送達システム / がん治療 / タンパク工学 / 抗体医薬 / 抗酸化アルブミン / 体内動態特性 / ハイブリッド型抗酸化アルブミン / 包括的放射線防護療法 / 組織指向性機能性アルブミン / structural property / functional property / pharmacokinetics / long half-life / antioxidant activity / albumin preparation / recombinant / 機能特性 / 構造特性 / 血中滞留性 / 機能性アルブミン製剤 / 遺伝子組換え体 / Clinical application / 臨床応用 / 機能性評価 / 分子設計 / amino acid residue / topology analysis / flunitrazepam / ketoprofen / photoaffinity labeling / serum albumin / 阻害挙動 / プローブ / フルニトラゼバム / アミノ酸残基 / トポロジー解析 / フルニトラゼパム / ケトプロフェン / 光アフィニティラベル / 血清アルグミン / dissolution / absorption / drug / polysaccharide / protein / natural polymer / pharmaceutical improvement / 動態学的特性 / 生物学的性質 / ケラチン / 溶出特性 / 毒性 / カゼイン / 卵白アルブミン / 多糖類 / 蛋白質 / 吸収性 / 溶解性 / 速効性用担体 / 製剤素材 / Species Difference / Microenvironmental Analysis / Point-mutation / Probe / Drug Binding Site / Albumin / N-B転移 / プローブ法 / 蛋白結合 / 立体構造 / 薬物結合性 / アニマルスケールアップ / 結合サイト / 種差 / microviscosity / optimal size / hydrophobicity / fluorescent probe / microenvironment analysis / alpha_1-acid glycoprotein / human serum albumin / 微粘性 / 至適サイズ / 疎水性 / 螢光プロ-ブ / α_1ー酸性糖蛋白質 / 腫瘍治療効果 / 抗がん剤 / 薬力学的評価 / 体内動態解析 / デリバリーシステム / 骨髄指向性 / チオレドキン / 肝障害 / 病態モデル / 多臓器不全治療 / レドックス / ナノメディスン / 毒性中和 / ハイブリッド / 毒素中和 / 分子進化工学 / 血液浄化法 / 免疫沈降法 / ドメイン / ファージ / Aβ / Thioredexin 1 / 酸化ストレス / Thioredoxin 1 / ドラッグデリバリー / アルブミン循環透析療法 / ビリルビン / アルブミン変異体 / 血液浄化 / 動態特性 / S-ニトロソタンパク質 / 生理活性 / DDS / 組換え体 / リガンド結合能 / 異型アルブミン / チオレドキシン / ドラッグデリバリーシステム / 異種タンパク質 / 遺伝子組換え型アルブミン / 臓器特異性 / エスコートプロテイン / 遺伝子工学 / ノックダウンレセプター / 阻害効果 / 尿毒症物質 / 脂肪酸 / 薬物間相互作用 / 分子機能学的動態解析 / 血清蛋白結合 … More Except Principal Investigator アルブミン / ドラッグデリバリーシステム / 腎疾患 / 尿毒症物質 / 酸化ストレス / α_1-酸性糖タンパク質 / アクティブターゲティング / アルブミン受容体 / 酸化アルブミン / 副甲状腺ホルモン / 二次性副甲状腺機能亢進症 / 脂肪酸 / 腎障害 / 尿毒素 / ヒト血清アルブミン / 一酸化窒素 / バリアント / タンパク結合 / α1-酸性糖タンパク質 / 修飾アルブミン / ワクチン / がん治療 / ストレス / ドラッグデリバリー / ナノ粒子 / 膵臓がん / ナノファイバー / 多機能性 / 多機能性多糖 / シクロデキストリン / キトサン / 慢性腎不全 / 抗酸化作用 / 酸化ストレス関連疾患 / 慢性腎臓病 / 糸球体バリア / マクロファージ / アドリアマイシン腎障害 / α1-酸性糖蛋白質 / AGP / ビタミンD / 腎線維化 / macrophage / TLR4 / kidney disease / alfa1-acid glycoprotein / 腎-多臓器連関 / 骨格筋 / 腎ー多臓器連関 / 薬学 / ABCG2 / バイオマーカー / バイカーカー / Elovl6 / 腎病態 / 脂肪酸代謝 / CYP3A / 尿酸 / 筋萎縮 / al-acid elvconrotein / nrotein binding / biochemistry / 部位特異的変異法 / 薬物相互作用 / 変異体 / 光アフィニティラベル法 / マッピング / 薬物結合部位 / α-1酸性糖タンパク質 / α_1-正酸性糖タンパク質 / 生物物理化学 / cytochrome b562 / recombinant human serum albumin / human serum albumin / S-nitrosylation / α_1-acid glycoprotein / pyridoxalated hemoglobin polyoxyethylene conjugate / 血漿由来HSA / 組換え型HSA / 血流阻害抑制作用 / αー1酸性糖タンパク / ポリオキシエチレン・重合ヘモグロビン(PHP) / 人口酸素運搬体 / シトクロムb562変異体 / ミオグロビン変異体 / 変異アルブミン / 炎症 / 白血球走化性抑制作用 / 微細循環改善作用 / 細隙通過促進作用 / α-1酸性糖タンパク / 配位子結合性 / ミオグロビン / Cys残基 / シトクロムb562 / 組換え型アルブミン / S-ニトロソ化 / α_1酸性糖蛋白 / ピリドキシル化ポリオキシエチレンヘモグロビン重合体 / 慢性腎障害 / 甲状腺ホルモン / トランスポーター / NADPH oxidase / 血管障害 / アルブミン尿 / 個別化医療 / 心血管障害 / α１－酸性糖タンパク質 / 抗菌活性 / 多剤耐性 / alpha-1酸性糖タンパク質 / ビリルビン排泄促進剤 / ランダム変異 / ファージディスプレイ / 分子進化工学 / タンパク質工学 / ビリルビン / 薬物認識 / 癌治療 / DDS / 薬物輸送 / 血清アルブミン / 膜インターフェイス / 分子標的薬 / α_<1->酸性糖タンパク質 / 肝取り込み / X線結晶構造解析 / リガンド結合 / 体内動態 / 多型情報 / 血清タンパク質 Less

Development of innovative albumin DDS carriers utilizing the characteristics of various albumin-interacting protein
- Principal Investigator
  
  異島優
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
Development of albumin DDS carrier based on an understanding of the endogenous albumin transport system
- Principal Investigator
  
  Ishima Yu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
  The University of Tokushima
Development of Innovative Antibody Drugs using Multifunctional Albumin as a Carrier for Low-molecular-weight AntibodiesPrincipal Investigator
- Principal Investigator
  
  Otagiri Masaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Sojo University
Development of novel multifunctional nanoparticles based on uptake mechanism of endogenous albumin by pancreatic cancer cells
- Principal Investigator
  
  ISHIMA Yu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
Treatment strategy based on the pathophysiology of renal-multi-organ axis induced by pathogenic albumin
- Principal Investigator
  
  Watanabe Hiroshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Treatment strategy for kidney disease based on TLR4-macrophage control by alfa1-acid glycoprotein
- Principal Investigator
  
  Watanabe Hiroshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Development of novel hybrid anti-oxidant based on albumin fusion technology and its therapeutic application on acute radiation syndromePrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
Multifaceted antioxidant evaluation of medicine and functional food for chronic renal failure
- Principal Investigator
  
  ANRAKU Makoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
Strategy for the personalized CKD medicine based on the crosstalk between albumin-bound uremic toxin and kidney
- Principal Investigator
  
  Hiroshi Watanabe
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Molecular mechanism of transportsome in chronic kidney disease and the involvement of thyroid hormone
- Principal Investigator
  
  Ayaka Suenaga
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Construction of an Innovative Bone Marrow Delivery System of Anticancer Drug for Control of Malignant Tumors' Bone MetastasisPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
Development of functional human serum albumin (HSA) mutants and studies of their ABT recognition mechanisms
- Principal Investigator
  
  MORIOKA HIROSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
Design and Evaluation of Next Generation Albumin-thioredoxin Fusion Protein for Multiple Organ Failure TreatmentPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
S-Nitrosated Alpha-1-acid Glycoprotein Kills Drug-resistant Bacteria and Aids Survival in Sepsis
- Principal Investigator
  
  MARUYAMA Toru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
The NO conjugated-albumin nanoparticles for the application to multidisciplinary cancer treatment
- Principal Investigator
  
  MARUYAMA Toru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Development of effective blood purification treatment method usingHSA bound toxic comnpodus designed bpyhase display tecnohlogyPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
Development of Redox Controlling Nanomedicine Based on Albumin FusionPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Sojo University
Study on the serum protein-mediated drug transport in biological membrane interface
- Principal Investigator
  
  YAMASAKI Keishi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sojo University
Aβペプチド捕獲型アルブミン製剤の開発とアルツハイマー病治療への応用Principal Investigator
- Principal Investigator
  
  小田切優樹
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Sojo University
Strategy for the personalized medicine of molecular target drug based on the polymorphism information of plasma protein
- Principal Investigator
  
  MARUYAMA Toru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
毒素捕獲型アルブミン変異体による安全な肝移植を目指した新規血液浄化法の開発Principal Investigator
- Principal Investigator
  
  小田切優樹
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Application of functional recombinant HSAs as a DDS carrierPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Mapping of drug binding sites on al-acid glycoprotein
- Principal Investigator
  
  MARUYAMA Toru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
血清アルブミンの新展開:ノックダウンレセプター及びエスコートプロテインとしての可能性Principal Investigator
- Principal Investigator
  
  小田切優樹
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kumamoto University
The development of next-generation albumin preparation by mutagenesi s studiesPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kumamoto University
Design and Evaluation of Albumin Mutants for Clinical ApplicationPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  KUMAMOTO UNIVERSITY
Application of plasma proteins as blood substitutes
- Principal Investigator
  
  NISHI Katsuhide
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  General pharmacology
- Research Institution
  KUMAMOTO UNIVERSITY
Design and Functional Evaluation of Albumin Mutants for Improving Medicinal EfficacyPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KUMAMOTO UNIVERSITY
病態時における薬物の血清蛋白結合の分子機能学的動態解析Principal Investigator
- Principal Investigator
  
  小田切優樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
Topology Analysis of Drug Binding Sites on Serum Proteins using Photoaffinity Labeling TechniquesPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KUMAMOTO UNIVERSITY
Development of Pharmaceutical Additives-Evaluation of Protein and Polysaccharide Hydrolysates as Carrier to Enhance Absorption Rate of DrugPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
Microenviromental Analysis of Drug Binding Site on Albumin by Point-mutation and Using ProbePrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
Microenvironmental Analysis of Drug Binding Sites on Human Serum Albumin and alpha_1-Acid GlycoproteinPrincipal Investigator
- Principal Investigator
  
  OTAGIRI Masaki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University

[Book] Human Serum Albumin (HSA): Functional Structure, Synthesis and Therapeutic Uses2015
- Author(s)
  Makoto Anraku, Ulrich Kragh-Hansen, Toru Maruyama and Masaki Otagiri
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-26460248
[Book] 薬剤学実験法必携マニュアル　Ⅱ生物薬剤学　4.薬物分布実験　タンパク結合：血漿・組織タンパク結合2014
- Author(s)
  小田切優樹、　丸山　徹
- Total Pages
  423
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-25670085
[Book] 薬剤学実験法必携マニュアル　Ⅱ生物薬剤学　4.薬物分布実験　タンパク結合：血漿・組織タンパク結合2014
- Author(s)
  小田切　優樹、　丸山　徹
- Total Pages
  423
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24390043
[Book] HUMAN SERUM ALBUMIN2013
- Author(s)
  MasakiOtagiri
- Total Pages
  510
- Publisher
  Sojo University Publishing Center
- Data Source
  KAKENHI-PROJECT-24390043
[Book] HUMAN SERUM ALBUMIN2013
- Author(s)
  Masaki Otagiri
- Total Pages
  510
- Publisher
  Sojo University Publishing Center
- Data Source
  KAKENHI-PROJECT-25670085
[Book] ACUTE PHASE PROTEINS2013
- Author(s)
  MasakiOtagiri
- Total Pages
  180
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-24390043
[Book] ACHUTE PHASE PROTEINS2013
- Author(s)
  Masaki Otagiri
- Total Pages
  180
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-25670085
[Book] HUMAN SERUM ALBUMIN2011
- Author(s)
  Masaki Otagiri(Ed)
- Total Pages
  300
- Publisher
  Sojo University Publishing Center
- Data Source
  KAKENHI-PROJECT-21390177
[Book] HUMAN SERUM ALBUMIN2011
- Author(s)
  Masaki Otagiri (Ed)
- Total Pages
  300
- Publisher
  Sojo University Publishing Center
- Data Source
  KAKENHI-PROJECT-23659088
[Book] HUMAN SERUM ALBUMIN2011
- Author(s)
  Masaki Otagiri (Ed)
- Total Pages
  300
- Publisher
  Sojo University Publishing Center
- Data Source
  KAKENHI-PROJECT-21390177
[Book] RIの逆襲 : アイソトープを活用した簡単・安全バイオ実験2007
- Author(s)
  安楽誠, 末永綾香, 小田切優樹
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Characterization of Supersulfide in Serum Albumin and Its Therapeutic Application2024
- Author(s)
  Ikeda Mayumi、Fukuta Tatsuya、Iwao Yasunori、Otagiri Masaki、Maruyama Toru、Ishida Tatsuhiro、Ishima Yu
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 144 Issue: 1 Pages: 51-56
- DOI
  10.1248/yakushi.23-00162-3
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2024-01-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02645
[Journal Article] Acute Kidney Injury Caused by Rhabdomyolysis Is Ameliorated by Serum Albumin-Based Supersulfide Donors through Antioxidative Pathways2024
- Author(s)
  Ikeda-Imafuku Mayumi、Fukuta Tatsuya、Tuan Giam Chuang Victor、Sawa Tomohiro、Maruyama Toru、Otagiri Masaki、Ishida Tatsuhiro、Ishima Yu
- Journal Title
  
  Pharmaceuticals
  
  Volume: 17 Issue: 1 Pages: 128-128
- DOI
  10.3390/ph17010128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17979, KAKENHI-PLANNED-21H05267, KAKENHI-PROJECT-21H02071, KAKENHI-PROJECT-21H02645
[Journal Article] Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis2023
- Author(s)
  Yasuda K, Maeda H, Kinoshita R, Minayoshi Y, Mizuta Y, Nakamura Y, Imoto S, Nishi K, Yamasaki K, Sakuragi M, Nakamura T, Ikeda-Imafuku M, Iwao Y, Ishima Y, Ishida T, Iwakiri Y, Otagiri M, Watanabe H, Maruyama T
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 17 Pages: 16668-16681
- DOI
  10.1021/acsnano.3c02877
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03406, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-23K28431
[Journal Article] Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH.2022
- Author(s)
  Sonoda K, Wakayama T, Kinoshita M, Shuto T, Kai H, Tanaka M, Sasaki Y, Iwakiri Y, Otagiri M
- Journal Title
  
  J Control Release
  
  Volume: 341 Pages: 457-474
- DOI
  10.1016/j.jconrel.2021.11.039
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K07134, KAKENHI-PROJECT-21K15315, KAKENHI-PROJECT-21H03038
[Journal Article] Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts2022
- Author(s)
  Beppu Takuro、Nishi Koji、Imoto Shuhei、Araki Waka、Setoguchi Itaru、Ueda Ayaka、Suetsugi Naho、Ishima Yu、Ikeda Tokunori、Otagiri Masaki、Yamasaki Keishi
- Journal Title
  
  Oncology Reports
  
  Volume: 48 Issue: 4 Pages: 178-178
- DOI
  10.3892/or.2022.8393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K07193, KAKENHI-PROJECT-21K19716, KAKENHI-PROJECT-20K06995
[Journal Article] The New Delivery Strategy of Albumin Carrier Utilizing the Interaction with Albumin Receptors2022
- Author(s)
  Ishima Yu、Maruyama Toru、Otagiri Masaki、Chuang Victor T. G.、Ishida Tatsuhiro
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 70 Issue: 5 Pages: 330-333
- DOI
  10.1248/cpb.c21-01024
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2022-05-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-21K19716
[Journal Article] Reduction-responsive and multi-drug deliverable albumin nanoparticles: an antitumor drug to Abraxane_ against human pancreatic tumor-bearing mice2021
- Author(s)
  Naoki Hirakawa, Yu Ishima, Ryo Kinoshita, Ryuto Nakano, Victor Tuan Giam Chuang, Hidenori Ando, Taro Shimizu, Keiichiro Okuhira, Toru Maruyama, Masaki Otagiri, Tatsuhiro Ishida
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 268 Issue: 5 Pages: 4302-4309
- DOI
  10.1021/acsabm.1c00110
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20H04124, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-21K19716
[Journal Article] A mannosylated ,PEGylated albumin as a drug delivery system for the treatment of cancer stroma cells.2021
- Author(s)
  Mizuta Y, Maeda H, Ishima T, Minayoshi Y, Ichimizu S, Kinoshita R, Fujita I, Kai T, Hirata H, Nakamura T, Saruwari J, Arima H, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Adv Funct Mater
  
  Volume: 31 Issue: 43 Pages: 2104136-2104136
- DOI
  10.1002/adfm.202104136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19J23629, KAKENHI-PROJECT-21K06514, KAKENHI-PROJECT-21K15315
[Journal Article] The Therapeutic Effect of Human Serum Albumin Dimer-Doxorubicin Complex against Human Pancreatic Tumors.2021
- Author(s)
  Kinoshita R, Ishima Y, Chuang VTG, Watanabe H, Shimizu T, Ando H, Okuhira K, Otagiri M, Ishida T, Maruyama T
- Journal Title
  
  Pharmaceutics.
  
  Volume: 13 Issue: 8 Pages: 1209-1209
- DOI
  10.3390/pharmaceutics13081209
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20H04124, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-21K19716
[Journal Article] Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions2021
- Author(s)
  Yamasaki Keishi、Kawai Akito、Sakurama Keiki、Udo Nagiko、Yoshino Yuta、Saito Yuki、Tsukigawa Kenji、Nishi Koji、Otagiri Masaki
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 18 Issue: 3 Pages: 1061-1070
- DOI
  10.1021/acs.molpharmaceut.0c01004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K16060, KAKENHI-PROJECT-20K06995
[Journal Article] Pharmacokinetics of 4′-cyano-2′-deoxyguanosine, a novel nucleoside analog inhibitor of the resistant hepatitis B virus, in a rat model of chronic kidney disease2021
- Author(s)
  Hashimoto Mai、Taguchi Kazuaki、Imoto Shuhei、Yamasaki Keishi、Mitsuya Hiroaki、Otagiri Masaki
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 5 Pages: 702-706
- DOI
  10.1016/j.jiac.2020.12.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] When Albumin Meets Liposomes: A Feasible Drug Carrier for Biomedical Applications.2021
- Author(s)
  Taguchi K, Okamoto Y, Matsumoto K, Otagiri M, Chuang VTG.
- Journal Title
  
  Pharmaceuticals (Basel)
  
  Volume: 14 Issue: 4 Pages: 296-296
- DOI
  10.3390/ph14040296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810
[Journal Article] Drug Delivery System for Refractory Cancer Therapy <i>via</i> an Endogenous Albumin Transport System2020
- Author(s)
  Ishima Yu、Maruyama Toru、Otagiri Masaki、Ishida Tatsuhiro
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 7 Pages: 583-588
- DOI
  10.1248/cpb.c20-00026
- NAID
  130007867325
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604
[Journal Article] Effects of Oxidation of Human Serum Albumin on the Binding of Aripiprazole2020
- Author(s)
  Sakurama Keiki、Nishi Koji、Chuang Victor Tuan Giam、Hashimoto Mai、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 6 Pages: 1023-1026
- DOI
  10.1248/bpb.b20-00205
- NAID
  130007850247
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Effect of Cinacalcet on the Redox Status of Albumin in Secondary Hyperparathyroidism Patients Receiving Hemodialysis2020
- Author(s)
  Imafuku Tadashi、Tanaka Motoko、Tokunaga Koki、Miyamura Shigeyuki、Kato Hiromasa、Tanaka Shoma、Nakano Takehiro、Hirata Kenshiro、Kadowaki Daisuke、Maeda Hitoshi、Matsushita Kazutaka、Otagiri Masaki、Komaba Hirotaka、Fukagawa Masafumi、Watanabe Hiroshi、Maruyama Toru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 10 Pages: 1583-1590
- DOI
  10.1248/bpb.b20-00472
- NAID
  130007920876
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-20H03406, KAKENHI-PROJECT-18K06774
[Journal Article] Carbon monoxide rescues the developmental lethality of experimental rat models of rhabdomyolysis-induced acute kidney injury2020
- Author(s)
  Taguchi K, Ogaki S, Nagasaki T, Yanagisawa H, Nishida K, Maeda H, Enoki Y, Matsumoto K, Sekijima H, Ooi K, Ishima Y, Watanabe H, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 372(3) Issue: 3 Pages: 355-365
- DOI
  10.1124/jpet.119.262485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-17K08481, KAKENHI-PROJECT-18H02587
[Journal Article] Evaluation of cytochrome P450-based drug metabolism in hemorrhagic shock rats that were transfused with native and an artificial red blood cell preparation, Hemoglobin-vesicles2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Sakai Hiromi、Ohtsuki Sumio、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 5 Pages: 417-424
- DOI
  10.1016/j.dmpk.2020.06.004
- NAID
  50014592883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Characterization of the Interaction of Daptomycin With Site II on Human Serum Albumin2020
- Author(s)
  Yamasaki Keishi、Sakurama Keiki、Nishi Koji、Watanabe Hiroshi、Maruyama Toru、Seo Hakaru、Otagiri Masaki、Taguchi Kazuaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 9 Pages: 2919-2924
- DOI
  10.1016/j.xphs.2020.06.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-20K06995
[Journal Article] Systemic and sustained thioredoxin analogue prevents acute kidney injury and its-associated distant organ damage in renal ischemia reperfusion injury mice2020
- Author(s)
  Nishida K, Watanabe H, Miyahisa M, Hiramoto Y, Nosaki H, Fujimura R, Maeda H, Otagiri M, and Maruyama M
- Journal Title
  
  Sci Rep.
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05114
[Journal Article] Hepatic Cytochrome P450 Profiles in Hemorrhagic Shock Model Rats After Transfusion With Stored Red Blood Cells2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 11 Pages: 3490-3495
- DOI
  10.1016/j.xphs.2020.08.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Serum Albumin, Lipid and Drug Binding2020
- Author(s)
  Nishi Koji、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Subcell Biochem
  
  Volume: 94 Pages: 383-397
- DOI
  10.1007/978-3-030-41769-7_15
- ISBN
  9783030417680, 9783030417697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810
[Journal Article] Repeated Administration of Kupffer Cells-Targeting Nanoantioxidant Ameliorates Liver Fibrosis in an Experimental Mouse Model2020
- Author(s)
  Maeda H, Minayoshi Y, Ichimizu S, Mizuta Y, Nagasaki T, Matsusaka K, Oshiro S, Oniki K, Saruwatari J, Ishima Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 1 Pages: 93-101
- DOI
  10.1248/bpb.b19-00599
- NAID
  130007779193
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-18H02587
[Journal Article] Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin2020
- Author(s)
  Tsukigawa Kenji、Imoto Shuhei、Yamasaki Keishi、Nishi Koji、Tsutsumi Toshihiko、Yokoyama Shoko、Ishima Yu、Otagiri Masaki
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Issue: 1 Pages: 22-22
- DOI
  10.3390/ph14010022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K16467, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-20K06995
[Journal Article] Assessing cytochrome P450-based drug-drug interactions with hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Sakai Hiromi、Ohtsuki Sumio、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 5 Pages: 425-431
- DOI
  10.1016/j.dmpk.2020.06.005
- NAID
  50014592884
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape2019
- Author(s)
  Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Ikegami Komei、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Shimizu Taro、Ishima Yu、Ishida Tatsuhiro、Seki Takahiro、Katsuki Hiroshi、Futaki Shiroh、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 304 Pages: 156-163
- DOI
  10.1016/j.jconrel.2019.05.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K07123, KAKENHI-PROJECT-16H04673, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
[Journal Article] Albumin domain mutants with enhanced Aβ binding capacity identified by phage display analysis for application in various peripheral Aβ elimination approaches of Alzheimer's disease treatment2019
- Author(s)
  Ishima Yu、Mimono Ai、Tuan Giam Chuang Victor、Fukuda Tetsuya、Kusumoto Kohshi、Okuhira Keiichiro、Suwa Yoshiaki、Watanabe Hiroshi、Ishida Tatsuhiro、Morioka Hiroshi、Maruyama Toru、Otagiri Masaki
- Journal Title
  
  IUBMB Life
  
  Volume: 72 Issue: 4 Pages: 641-651
- DOI
  10.1002/iub.2203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-20H04124
[Journal Article] Investigation of anti-tumor effect of doxorubicin-loaded human serum albumin nanoparticles prepared by a desolvation technique.2019
- Author(s)
  Kimura K, Yamasaki K, Nishi K, Taguchi K, Otagiri M
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 83 Issue: 6 Pages: 1113-1120
- DOI
  10.1007/s00280-019-03832-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17K08261
[Journal Article] Preparation, Characterization, and in Vitro/in Vivo Evaluation of Paclitaxel-Bound Albumin-Encapsulated Liposomes for the Treatment of Pancreatic Cancer2019
- Author(s)
  Okamoto Yuko、Taguchi Kazuaki、Sakuragi Mina、Imoto Shuhei、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  ACS Omega
  
  Volume: 4 Issue: 5 Pages: 8693-8700
- DOI
  10.1021/acsomega.9b00537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17K08261
[Journal Article] S-Nitrosated alpha-1-acid glycoprotein exhibits antibacterial activity against multidrug-resistant bacteria strains and synergistically enhances the effect of antibiotics2019
- Author(s)
  Ishima Yu、Watanabe Kaori、Chuang Victor T. G.、Takeda Iyo、Kuroda Teruo、Ogawa Wakano、Watanabe Hiroshi、Iwao Yasunori、Ishida Tatsuhiro、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 1 Issue: 3 Pages: 137-150
- DOI
  10.1096/fba.1018
- NAID
  120007153321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
[Journal Article] Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.2019
- Author(s)
  Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Ikegami K, Chuang VTG, Kinoshita R, Nishida K, Shimizu T, Ishima Y, Ishida T, Seki T, Katsuki H, Futaki S, Otagiri M, Maruyama T
- Journal Title
  
  J Control Release.
  
  Volume: S0168-3659 Pages: 30174-30177
- DOI
  10.1016/j.jconrel.2020.03.022
- Data Source
  KAKENHI-PROJECT-16H05114
[Journal Article] Distribution of Polysulfide in Human Biological Fluids and Their Association with Amylase and Sperm Activities2019
- Author(s)
  Ikeda Mayumi、Ishima Yu、Chuang Victor T. G.、Sakai Maki、Osafune Hiroki、Ando Hidenori、Shimizu Taro、Okuhira Keiichiro、Watanabe Hiroshi、Maruyama Toru、Otagiri Masaki、Akaike Takaaki、Ishida Tatsuhiro
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 9 Pages: 1689-1689
- DOI
  10.3390/molecules24091689
- NAID
  120006995454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-18H05277
[Journal Article] Genetic Fusion of Type-I Interferon to a Recombinant Albumin Mutant with polymannosylated N-linked oligosaccharide attached is a Novel and Superior Kupffer Cell Targeting Agent for the Treatment of Hepatitis.2018
- Author(s)
  Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Drug Delivery
  
  Volume: 25 Issue: 1 Pages: 1067-1077
- DOI
  10.1080/10717544.2018.1464083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02798
[Journal Article] A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis,2018
- Author(s)
  Ikeda M, Ishima Y, Kinoshita R, Chuang VTG, Tasaka N, Matsuo N, Watanabe H, Shimizu T, Ishida T, Otagiri M, Maruyama T,
- Journal Title
  
  Redox Biology
  
  Volume: 14 Pages: 354-360
- DOI
  10.1016/j.redox.2017.10.007
- NAID
  120007029979
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
[Journal Article] Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity.2018
- Author(s)
  Tanaka KI, Shimoda M, Chuang VTG, Nishida K, Kawahara M, Ishida T, Otagiri M, Maruyama T, Ishima Y.
- Journal Title
  
  Int J Pharm.
  
  Volume: 535 Issue: 1-2 Pages: 140-147
- DOI
  10.1016/j.ijpharm.2017.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587
[Journal Article] Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery2018
- Author(s)
  Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Nakamura Yuka、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Tanaka Ryota、Enoki Yuki、Ishima Yu、Kuniyasu Akihiko、Kobashigawa Yoshihiro、Morioka Hiroshi、Futaki Shiro、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 277 Pages: 23-34
- DOI
  10.1016/j.jconrel.2018.02.037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08383, KAKENHI-PROJECT-15K14983, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-18H02587
[Journal Article] Dual therapeutic effects of an albumin-based nitric oxide donor on two experimental models of chronic kidney disease2018
- Author(s)
  Oshiro S, Ishima Y, Maeda H, Honda N, Bi J, Kinoshita R, Ikeda M, Iwao Y, Imafuku T, Nishida K, Miyamura S, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  J Pharm Sci
  
  Volume: 107 Issue: 3 Pages: 848-855
- DOI
  10.1016/j.xphs.2017.10.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-16K15320, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
[Journal Article] The Binding of Silibinin, the Main Constituent of Silymarin, to Site I on Human Serum Albumin2017
- Author(s)
  Yamasaki K, Sato H, Minagoshi S, Kyubun K, Anraku M, Miyamura S, Watanabe H, Taguchi K, Seo H, Maruyama T, Otagiri M
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 3 Pages: 310-317
- DOI
  10.1248/bpb.b16-00790
- NAID
  130005398492
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-17K08480
[Journal Article] Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases.2017
- Author(s)
  Watanabe H, Imafuku T, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: S0022-3549 Issue: 9 Pages: 18-25
- DOI
  10.1016/j.xphs.2017.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-16H05114, KAKENHI-PROJECT-16K15320, KAKENHI-PROJECT-17J11624
[Journal Article] An oral absorbent, surface-deacetylated chitin nano-fiber ameliorates renal injury and oxidative stress in 5/6 nephrectomized rats2017
- Author(s)
  Makoto Anraku, Ryo Tabuchi, Shinsuke Ifuku, Tomone Nagae, Daisuke Iohara, Hisao Tomida, Kaneto Uekama, Toru Maruyama, Shigeyuki Miyamura, Fumitoshi Hirayama, Masaki Otagiri
- Journal Title
  
  Carbohydrate Polymers
  
  Volume: 161 Pages: 21-25
- DOI
  10.1016/j.carbpol.2016.12.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02998, KAKENHI-PROJECT-26708026, KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-17K08480
[Journal Article] Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction2017
- Author(s)
  Enoki Y, Watanabe H, Arake R, Fujimura R, Ishiodori K, Imafuku K, Nishida K, Sugimoto R, Nagao S, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  J Cachexia Sarcopenia Muscle
  
  Volume: 8 Issue: 5 Pages: 735-747
- DOI
  10.1002/jcsm.12202
- NAID
  120006869527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05114
[Journal Article] Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism2017
- Author(s)
  Watanabe H, Sugimoto R, Ikegami K, Enoki Y, Imafuku T, Fujimura R, Bi J, Nishida K, Sakaguchi Y, Murata M, Maeda H, Hirata K, Jingami S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 145 Pages: 192-201
- DOI
  10.1016/j.bcp.2017.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15320
[Journal Article] Quantitative determination of polysulfide in albumins, plasma proteins and biological fluid samples using a novel combined assays approach2017
- Author(s)
  keda, M. Ishima, Y. Shibata, A. Chuang, V. T. G. Sawa, T. Ihara, H. Watanabe, H. Xian, M. Ouchi, Y. Shimizu, T. Ando, H. Ukawa, M. Ishida, T. Akaike, T. Otagiri, M. Maruyama, T.
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 969 Pages: 18-25
- DOI
  10.1016/j.aca.2017.03.027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-17K19205, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-16K15208
[Journal Article] Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers.2017
- Author(s)
  Taguchi K, Yamasaki K, Maruyama T, Otagiri M.
- Journal Title
  
  J Funct Biomater.
  
  Volume: 8 Issue: 1 Pages: 0-0
- DOI
  10.3390/jfb8010011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-17K08481
[Journal Article] The down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism2017
- Author(s)
  Sugimoto R, Watanabe H, Ikegami K, Enoki Y, Imafuku T, Sakaguchi Y, Murata M, Nishida K, Miyamura M, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Toru Maruyama
- Journal Title
  
  Kidney Int
  
  Volume: 91 Issue: 3 Pages: 658-670
- DOI
  10.1016/j.kint.2016.09.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15320, KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-16H05114
[Journal Article] Oral branched-chain amino acid granules improve structure and function of human serum albumin in liver cirrhotic patients2017
- Author(s)
  Setoyama　H, Tanaka M, Nagumo K, Naoe H, Watanabe T, Yoshimaru Y, Tateyama M, Sasaki M, Watanabe H, Otagiri M, Maruyama T and Sasaki Y
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 6 Pages: 754-765
- DOI
  10.1007/s00535-016-1281-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173, KAKENHI-PROJECT-15K15008
[Journal Article] Comparison of Posttranslational Modification and the Functional Impairment of Human Serum Albumin in Commercial Preparations2016
- Author(s)
  Miyamura S, Imafuku T, Anraku M, Taguchi K, Yamasaki K, Tominaga Y, Maeda H, Ishima Y, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  J Pharm Sci.
  
  Volume: 105 Issue: 3 Pages: 1043-1049
- DOI
  10.1016/j.xphs.2015.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-26670569
[Journal Article] Human serum albumin hydropersulfide is a potent reactive oxygen species scavenger in oxidative stress conditions such as chronic kidney disease2016
- Author(s)
  Shibata A, Ishima Y, Ikeda M, Sato H, Imafuku T, Chuang VT, Ouchi Y, Abe T, Watanabe H, Ishida T, Otagiri M, Maruyama T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 479 Issue: 3 Pages: 578-583
- DOI
  10.1016/j.bbrc.2016.09.113
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05114, KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-26670569, KAKENHI-PROJECT-15K08076
[Journal Article] Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study2016
- Author(s)
  Tanaka M, Miyamura S, Imafuku T, Tominaga Y, Maeda H, Anraku M, Yamasaki K, Kadowaki D, Ishima Y, Watanabe H, Okuda T, Itoh K, Matsushita K, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 6 Pages: 1000-1006
- DOI
  10.1248/bpb.b15-01021
- NAID
  130005155137
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05114, KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-15K08100
[Journal Article] Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties.2016
- Author(s)
  Nagao S, Taguchi K, Sakai H, Yamasaki K, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Int J Nanomedicine.
  
  Volume: 11 Pages: 5611-5620
- DOI
  10.2147/ijn.s118185
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J09957, KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-26860121
[Journal Article] Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether b-cyclodextrin gel in wound dressing application2016
- Author(s)
  Ryo Tabuchi, Kazuo Azuma, Ryotaro Izumi, Tsubasa Tanou, Yoshiharu Okamoto, Tomone Nagae, Daisuke Iohara, Kaneto Uekama, Masaki Otagiri Fumitoshi Hirayama, Shinsuke Ifuku, Makoto Anraku
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 511 Issue: 2 Pages: 1080-1087
- DOI
  10.1016/j.ijpharm.2016.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26708026, KAKENHI-PROJECT-26460248
[Journal Article] Mutants and molecular dockings reveal that the primary L-thyroxine binding site in human serum albumin is not the one which can cause familial dysalbuminemic hyperthyroxinemia.2016
- Author(s)
  Kragh-Hansen U, Minchiotti L, Coletta A, Bienk K, Galliano M, Schiott B, Iwao Y, Ishima Y, Otagiri M
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1860 Issue: 4 Pages: 648-660
- DOI
  10.1016/j.bbagen.2016.01.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-15K08076
[Journal Article] Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties2016
- Author(s)
  Nagao S, Taguchi K, Sakai H, Yamasaki K, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Int J Nanomedicine
  
  Volume: 11 Pages: 5611-5620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15320
[Journal Article] Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-12016
- Author(s)
  Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 32084-32084
- DOI
  10.1038/srep32084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-16H05114, KAKENHI-PROJECT-15K15185, KAKENHI-PROJECT-16K08168, KAKENHI-PROJECT-16K15320
[Journal Article] Antioxidant and renoprotective activity of 2-hydroxypropyl-β-cyclodextrin in nephrectomized rats.2016
- Author(s)
  Anraku M, Iohara D, Wada K, Taguchi K, Maruyama T, Otagiri M, Uekama K, Hirayama F.
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 68 Issue: 5 Pages: 608-614
- DOI
  10.1111/jphp.12446
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460248
[Journal Article] Comparison of Posttranslational Modification and the Functional Impairment of Human Serum Albumin in Commercial Preparations2016
- Author(s)
  Miyamura S, Imafuku T, Anraku M, Taguchi K, Yamasaki K, Tominaga Y, Maeda H, Ishima Y, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  J Pharm Sci
  
  Volume: 105 Pages: 1043-1049
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05114
[Journal Article] N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl- L-tryptophan2016
- Author(s)
  Kouno Y, Anraku M, Yamasaki K, Okayama Y, Iohara D, Nakamura H, Maruyama T, Hirayama F, Kragh-Hansen U, Otagiri M.
- Journal Title
  
  Biochemistry and BiophysicsReports
  
  Volume: 6 Pages: 266-274
- DOI
  10.1016/j.bbrep.2016.04.011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-15K15008
[Journal Article] p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress.2015
- Author(s)
  Watanabe H, Miyamoto Y, Enoki Y, Ishima Y, Kadowaki D, Kotani S, Nakajima M, Tanaka M, Matsushita K, Mori Y, Kakuta T, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Pharmacol Res Perspect
  
  Volume: 3 Issue: 1
- DOI
  10.1002/prp2.92
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-25460652
[Journal Article] Establishment of a model of acetaminophen-induced hepatotoxicity in different weekly-aged ICR mice.2015
- Author(s)
  Taguchi K, Tokuno M, Yamasaki K, Kadowaki D, Seo H, Otagiri M
- Journal Title
  
  Lab Anim.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670085
[Journal Article] Cross-linked human serum albumin dimer has the potential for use as a plasma retaining-agent for the fatty acid-conjugated antidiabetic drugs.2015
- Author(s)
  Taguchi K, Chuang VTG, Yamasaki K, Urata Y, Tanaka R, Anraku M, Seo H, Kawai K, Maruyama T, Komatsu T, Otagiri M
- Journal Title
  
  J Pharm Pharmacol.
  
  Volume: 67 Issue: 2 Pages: 255-263
- DOI
  10.1111/jphp.12338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-15K15452, KAKENHI-PROJECT-25293260
[Journal Article] Interactions of Linezolid with Two Major Serum Proteins, Human Serum Albumin and Alpha-1 Acid Glycoprotein.2015
- Author(s)
  Taguchi K, Yamasaki1 K, Shiga A, Otagiri M, Seo H.
- Journal Title
  
  J. Pharmacol Clin Toxicol.
  
  Volume: 3 Pages: 1045-1045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043
[Journal Article] Interactions of Linezolid with Two Major Serum Proteins, Human Serum Albumin and Alpha-1 Acid Glycoprotein.2015
- Author(s)
  Taguchi K, Yamasaki1 K, Shiga A, Otagiri M, Seo H.
- Journal Title
  
  J. Pharmacol Clin Toxicol.
  
  Volume: 3 Pages: 1045-1045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670085
[Journal Article] Synthesis and therapeutic effect of styrene-maleic acid copolymer-conjugated pirarubicin.2015
- Author(s)
  Tsukigawa K, Liao L, Nakamura H, Fang J, Greish K, Otagiri M, Maeda H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 3 Pages: 270-278
- DOI
  10.1111/cas.12592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26860031
[Journal Article] Renoprotective effect of long acting thioredoxin by modulating oxidative stress and macrophage migration inhibitory factor against rhabdomyolysis-associated acute kidney injury.2015
- Author(s)
  Nishida K, Watanabe H, Ogaki S, Kodama A, Tanaka R, Imafuku T, Ishima Y, Giam Chuang VT, Toyoda M, Kondoh M, Wu Q, Fukagawa M, Otagiri M, Maruyama T.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 14471-14471
- DOI
  10.1038/srep14471
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-15K15185, KAKENHI-PROJECT-15H04758
[Journal Article] Effect of different chemical bonds in pegylation of zinc protoporphyrin that affects drug release, intracellular uptake, and therapeutic effect in the tumor.2015
- Author(s)
  Tsukigawa K, Nakamura H, Fang J, Otagiri M, Maeda H
- Journal Title
  
  Eur J Pharm Biopharm.
  
  Volume: 89 Pages: 259-270
- DOI
  10.1016/j.ejpb.2014.12.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26860031, KAKENHI-PROJECT-25430162
[Journal Article] Olmesartan protects endothelial cells against oxidative stress-mediated cellular injury.2015
- Author(s)
  Kadowaki D, Anraku M, Sakaya M, Hirata S, Maruyama T, Otagiri M.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 19 Issue: 6 Pages: 1007-1014
- DOI
  10.1007/s10157-015-1111-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-15K15008
[Journal Article] Poly-S-nitrosated human albumin enhances the antitumor and antimetastasis effect of bevacizumab, partly by inhibiting autophagy through the generation of nitric oxide.2015
- Author(s)
  Ishima Y, Inoue A, Fang J, Kinoshita R, Ikeda M, Watanabe H, Maeda H, Otagiri M, Maruyama T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 2 Pages: 194-200
- DOI
  10.1111/cas.12577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-25860118, KAKENHI-PROJECT-15K08076
[Journal Article] Polythiol-containing, recombinant mannosylated-albumin is a superior CD68+/CD206+ Kupffer cell-targeted nano-antioxidant for the treatment of two acute hepatitis models.2015
- Author(s)
  Maeda H, Hirata K, Watanabe H, Ishima Y, Chuang VT, Taguchi K, Inatsu A, Kinoshita M, Tanaka M, Sasaki Y, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 352 Issue: 2 Pages: 244-257
- DOI
  10.1124/jpet.114.219493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-26670569, KAKENHI-PROJECT-25293173, KAKENHI-PROJECT-25293369
[Journal Article] Amino acids of importance for the antioxidant activity of human serum albumin as revealed by recombinant mutants and genetic variants.2015
- Author(s)
  Anraku M, Shintomo R, Taguchi K, Kragh-Hansen U, Kai T, Maruyama T, Otagiri M.
- Journal Title
  
  Life Sci.
  
  Volume: 134 Pages: 36-41
- DOI
  10.1016/j.lfs.2015.05.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460248, KAKENHI-PROJECT-15K15008
[Journal Article] Safety Evaluation of Hemoglobin-Albumin Cluster "HemoAct" as a Red Blood Cell Substitute.2015
- Author(s)
  Haruki R, Kimura T, Iwasaki H, Yamada K, Kamiyama I, Kohno M, Taguchi K, Nagao S, Maruyama T, Otagiri M, Komatsu T.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 12778-12778
- DOI
  10.1038/srep12778
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008, KAKENHI-PROJECT-15K15185, KAKENHI-PROJECT-15H04758
[Journal Article] Albumin Fusion Prolongs the Antioxidant and Anti-Inflammatory Activities of Thioredoxin in Mice with Acetaminophen-Induced Hepatitis.2014
- Author(s)
  Tanaka R, Ishima Y, Maeda H, Kodama A, Nagao S, Watanabe H, Chuang VT, Otagiri M, Maruyama T.
- Journal Title
  
  Mol Pharm.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043
[Journal Article] Effects of chitosan on oxidative stress and related factors in hemodialysis patients.2014
- Author(s)
  Anraku M, Tanaka M, Hiraga A, Nagumo K, Imafuku T, Maezaki Y, Iohara D, Uekama K, Watanabe H, Hirayama F, Maruyama T, Otagiri M
- Journal Title
  
  Carbohydr Polym
  
  Volume: 112 Pages: 152-157
- DOI
  10.1016/j.carbpol.2014.05.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26460248
[Journal Article] Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate, a uremic toxin2014
- Author(s)
  Watanabe H, Sakaguchi Y, Sugimoto R, Kaneko K, Iwata H, Kotani S, Nakajima M, Ishima Y, Otagiri M, Maruyama T
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 18 Issue: 5 Pages: 814-20
- DOI
  10.1007/s10157-013-0902-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460652
[Journal Article] Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin2014
- Author(s)
  Sato H, Chuang VT, Yamasaki K, Yamaotsu N, Watanabe H, Nagumo K, Anraku M, Kadowaki D, Ishima Y, Hirono S, Otagiri M, Maruyama T
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e87919-e87919
- DOI
  10.1371/journal.pone.0087919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790211, KAKENHI-PROJECT-26460248
[Journal Article] Tuning of Poly-S-Nitrosated Human Serum Albumin as Superior Antitumor Nanomedicine2014
- Author(s)
  Ishima Y, Fang J, Kragh-Hansen U, Yin H, Liao L, Katayama N, Watanabe H, Kai T, Suenaga A, Maeda H, Otagiri M, Maruyama T
- Journal Title
  
  J Pharm Sci
  
  Volume: 103 Issue: 7 Pages: 2184-2188
- DOI
  10.1002/jps.24020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-25860118
[Journal Article] Therapeutic Impact of Human Serum Albumin-Thioredoxin Fusion Protein on Influenza Virus-Induced Lung Injury Mice.2014
- Author(s)
  Tanaka R, Ishima Y, Enoki Y, Kimachi K, Shirai T, Watanabe H, Chuang VT, Maruyama T, Otagiri M.
- Journal Title
  
  Front Immunol
  
  Volume: 5 Pages: 561-561
- DOI
  10.3389/fimmu.2014.00561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-25860118
[Journal Article] Preparation and antioxidant activity of PEGylated chitosans with different particle sizes.2014
- Author(s)
  Anraku M, Hiraga A, Iohara D, Uekama K, Tomida H, Otagiri M, Hirayama F.
- Journal Title
  
  Int J Biol Macromol.
  
  Volume: 70 Pages: 64-9
- DOI
  10.1016/j.ijbiomac.2014.06.026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460248
[Journal Article] Pleiotropic effects of chitosan on lifestyle-related diseases2014
- Author(s)
  Anraku M, Maruyama T, Iohara D, Tomida H, Hirayama F, Otagiri M.
- Journal Title
  
  Kichin, Kitosan Kenkyu
  
  Volume: 20 Pages: 74-81
- NAID
  40020148316
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460248
[Journal Article] N-acetyl-Lmethionine is a superior protectant of human serum albumin against photooxidation and reactive oxygen species compared to N-acetyl-L-tryptophan2014
- Author(s)
  Kouno Y, Anraku M, Yamasaki K, Okayama Y, Iohara D, Ishima Y, Maruyama T, Kragh-Hansen U, Hirayama F, Otagiri M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: (in press) Issue: 9 Pages: 2806-2812
- DOI
  10.1016/j.bbagen.2014.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790211, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26460248
[Journal Article] Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases2014
- Author(s)
  K. Nagumo, M. Tanaka, VT. Chuang, H. Setoyama, H. Watanabe, N. Yamada, K. Kubota, M. Tanaka, K. Matsushita, A. Yoshida, H. Jinnouchi, M. Anraku, D. Kadowaki, Y. Ishima, Y. Sasaki, M. Otagiri, T. Maruyama.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e85216-e85216
- DOI
  10.1371/journal.pone.0085216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790211, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-25860118, KAKENHI-PROJECT-26460248
[Journal Article] Albumin Fusion Prolongs the Antioxidant and Anti-Inflammatory Activities of Thioredoxin in Mice with Acetaminophen-Induced Hepatitis.2014
- Author(s)
  Tanaka R, Ishima Y, Maeda H, Kodama A, Nagao S, Watanabe H, Chuang VT, Otagiri M, Maruyama T.
- Journal Title
  
  Mol Pharm.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670085
[Journal Article] Carbon　monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by　massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450　protection in hemorrhagic shock rats.2014
- Author(s)
  Ogaki S, Taguchi K, Watanabe H, Ishima Y, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 103 Issue: 7 Pages: 2199-2206
- DOI
  10.1002/jps.24029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26860121
[Journal Article] Albumin fusion renders thioredoxin an effective anti-oxidative and anti-inflammatory agent for preventing cisplatin-induced nephrotoxicity.2014
- Author(s)
  Kodama A, Watanabe H, Tanaka R, Kondo M, Chuang VT, Wu Q, Endo M, Ishima Y, Fukagawa M, Otagiri M, Maruyama T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1840 Issue: 3 Pages: 1152-1162
- DOI
  10.1016/j.bbagen.2013.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-25670085
[Journal Article] Carbon monoxide-bound hemoglobin-vesicles for the　treatment of bleomycin-induced pulmonary fibrosis.2014
- Author(s)
  Nagao S, Taguchi K, Sakai H, Tanaka R, Horinouchi H, Watanabe H, Kobayashi K, Otagiri M, Maruyama T.
- Journal Title
  
  Biomaterials.
  
  Volume: 35 Issue: 24 Pages: 6553-6562
- DOI
  10.1016/j.biomaterials.2014.04.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24790159, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-26860121
[Journal Article] Therapeutic impact of erythropoietin-encapsulated liposomes targeted to bone marrow on renal anemia.2014
- Author(s)
  Miyazaki Y, Taguchi K, Sou K, Watanabe H, Ishima Y, Miyakawa T, Mitsuya H,　Fukagawa M, Otagiri M, Maruyama T.
- Journal Title
  
  Mol Pharm.
  
  Volume: 11 Issue: 11 Pages: 4238-4248
- DOI
  10.1021/mp500453a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-25860118, KAKENHI-PROJECT-26860121
[Journal Article] Albumin Fusion Prolongs the Antioxidant and Anti-Inflammatory Activities of Thioredoxin in Mice with Acetaminophen-Induced Hepatitis2014
- Author(s)
  Tanaka R, Ishima Y, Maeda H, Kodama A, Nagao S, Watanabe H, Chuang VT, Otagiri M, Maruyama T
- Journal Title
  
  Mol Pharm
  
  Volume: 印刷中 Issue: 4 Pages: 1228-1228
- DOI
  10.1021/mp400690v
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25860118
[Journal Article] p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase.2013
- Author(s)
  Watanabe H, Miyamoto Y, Honda D, Tanaka H, Wu Q, Endo M, Noguchi T, Kadowaki D, Ishima Y, Kotani S, Nakajima M, Kataoka K, Kim-Mitsuyama S, Tanaka M, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Kidney Int
  
  Volume: 83 Pages: 582-592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460190
[Journal Article] UW solution improved with high anti-apoptotic activity by S-nitrosated human serum albumin.2013
- Author(s)
  Ishima Y
- Journal Title
  
  Nitric Oxide.
  
  Volume: 印刷中 Pages: 36-42
- DOI
  10.1016/j.niox.2013.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25670085
[Journal Article] Redox properties of serum albumin.2013
- Author(s)
  Anraku M, Chuang VT, Maruyama T, Otagiri M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1830 Issue: 12 Pages: 5465-5472
- DOI
  10.1016/j.bbagen.2013.04.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23790211, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085
[Journal Article] Pharmacokinetic alteration of (99m)Tc-MAG3 using serum protein binding displacement method.2013
- Author(s)
  Nishi K, Kobayashi M, Nishii R, Shikano N, Takamu ra N, Kuga N, Yamasaki K, Nagamachi S, Tamura S, Otagiri M, Kawai K.
- Journal Title
  
  Nucl Med Biol.
  
  Volume: 40 Pages: 366-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy.2013
- Author(s)
  Taguchi K, Jono H, Kugimiya-Taguchi T, Nagao S, Su Y, Yamasaki K, Mizuguchi M, Maruyama T, Ando Y, Otagiri M.
- Journal Title
  
  Life Sci.
  
  Volume: 18 Issue: 25-26 Pages: 1017-22
- DOI
  10.1016/j.lfs.2013.10.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085
[Journal Article] A human serum albumin-thioredoxin fusion protein prevents experimental contrast-induced nephropathy.2013
- Author(s)
  Kodama A
- Journal Title
  
  Kidney Int.
  
  Volume: 印刷中 Issue: 3 Pages: 446-54
- DOI
  10.1038/ki.2012.429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-23790187, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Carbon Monoxide Bound Red Blood Cells Protect Red Blood Cell Transfusion-induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-shock Rats. Drug Metab Dispos.2013
- Author(s)
  Ogaki S, Taguchi K, Watanabe H, Otagiri M, and Maruyama T.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 41 Issue: 1 Pages: 141-8
- DOI
  10.1124/dmd.112.048744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24790159
[Journal Article] S-nitrosylated a-l-acid glycoprotein kills drug-resistant bacteria and aids survival in sepsis2013
- Author(s)
  Watanabe K, Ishima Y, Akaike T, Sawa T, Kuroda T, Ogawa W, Watanabe H, Suenaga A, Kai T, Otagiri M, and Maruyama T.
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 1 Pages: 391-398
- DOI
  10.1096/fj.12-217794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-22590064, KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23651239, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25220103
[Journal Article] Albumin-drug interaction and its clinical implication.2013
- Author(s)
  Yamasaki K, Chuang VT, Maruyama T, Otagiri M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1830 Issue: 12 Pages: 5435-43
- DOI
  10.1016/j.bbagen.2013.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25670085
[Journal Article] A human serum albumin-thioredoxin fusion protein prevents experimental contrast-induced nephropathy2013
- Author(s)
  Kodama A, Watanabe H, Tanaka R, Tanaka H, Chuang VT, Miyamoto Y, Wu Q, Endo M, Hamasaki K, Ishima Y, Fukagawa M, Otagiri M, Maruyama T
- Journal Title
  
  Kidney Int
  
  Volume: 83 Pages: 446-454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460190
[Journal Article] Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment.2013
- Author(s)
  Minomo A
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 印刷中 Issue: 4 Pages: 141-8
- DOI
  10.1016/j.bbagen.2013.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390028, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25670085
[Journal Article] S-nitrosated α-1-acid glycoprotein kills drug-resistant bacteria and aids survival in sepsis2013
- Author(s)
  Watanabe K, Ishima Y, Akaike T, Sawa T, Kuroda T, Ogawa W, Watanabe H, Suenaga A, Kai T, Otagiri M, Maruyama T
- Journal Title
  
  FASEB J
  
  Volume: 27 Pages: 391-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460652
[Journal Article] Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression2013
- Author(s)
  Tanaka R, Watanabe H, Kodama A, Chuang VT, Ishima Y, Hamasaki K, Tanaka K, Mizushima T, Otagiri M, Maruyama T
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 345 Pages: 271-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460190
[Journal Article] Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin.2013
- Author(s)
  Watanabe H
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 40 Issue: 7 Pages: 1423-8
- DOI
  10.1124/dmd.112.045617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-23790187, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Poly-s-nitrosated albumin as a safe and effective multifunctional antitumor agent : characterization, biochemistry and possible future therapeutic applications2013
- Author(s)
  Ishima Y, Kragh-Hansen U, Maruyama T, Otagiri M
- Journal Title
  
  Biomed Res Int
  
  Volume: 2013 Pages: 353892-353892
- DOI
  10.1155/2013/353892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-25860118
[Journal Article] Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression.2013
- Author(s)
  Tanaka R, Watanabe H, Kodama A, Chuang VT, Ishima Y, Hamasaki K, Tanaka K, Mizushima T, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 345 Issue: 2 Pages: 271-283
- DOI
  10.1124/jpet.112.201814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659037, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-24790077
[Journal Article] Characterization of hepatic cellular uptake of α1-acid glycoprotein (AGP), part 2: Involvement of hemoglobin β-chain on plasma membranes in the uptake of human AGP by liver parenchymal cells.2012
- Author(s)
  Komori H, Nishi K, Uehara N, Watanabe H, Shuto T, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 101 Pages: 1607-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] α(1)-Acid glycoprotein up -regulates CD163 via TLR4/CD14 protein pathway: possible protection against hemolysis-induced oxidative stress.2012
- Author(s)
  Komori H, Watanabe H, Shuto T, Kodama A,Maeda H, Watanabe K, Kai H, Otagiri M, Maruyama T.
- Journal Title
  
  J Biol Chem.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] A fourteen-day observation and pharmacokinetic evaluation after a massive intravenous infusion of hemoglobin-vesicles (artificial oxygen carriers) in cynomolgus monkeys.2012
- Author(s)
  Taguchi K, Watanabe H, Sakai H, Horinouchi H, Kobayashi K, Maruyama T, and Otagiri M
- Journal Title
  
  J Drug Metab Toxicol.
  
  Volume: 3 Issue: 4 Pages: 128-34
- DOI
  10.4172/2157-7609.1000128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043
[Journal Article] Elucidation of the therapeutic enhancer mechanism of poly -S-nitrosated human serum albumin against multidrug-resistant tumor in animal models.2012
- Author(s)
  Ishima Y, Hara M, Kragh-Hansen U, Inoue A, Suenaga A, Kai T, Watanabe HOtagiri M, Maruyama T .
- Journal Title
  
  J Control Release.
  
  Volume: 164 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] S-Nitrosated human serum albumin dimer is not only a novel anti-tumor drug but also a potentiator for anti-tumor drugs with augmented EPR effects2012
- Author(s)
  Ishima Y
- Journal Title
  
  Bioconjug Chem
  
  Volume: 23 Issue: 2 Pages: 264-271
- DOI
  10.1021/bc2005363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142
[Journal Article] Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants2012
- Author(s)
  Iwao Y
- Journal Title
  
  IUBMB Life
  
  Volume: 64 Issue: 5 Pages: 450-454
- DOI
  10.1002/iub.567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043
[Journal Article] Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B.2012
- Author(s)
  Kaneko K, Chuang VT, Ito T, Suenaga A, Watanabe H, Maruyama T, Otagiri M. Pharmazie.
- Journal Title
  
  Pharmazie.
  
  Volume: 67 Pages: 414-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants2012
- Author(s)
  Iwao Y, Ishima Y, Yamada J, Noguchi T, Kragh-Hansen U, Mera K, Honda D, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  IUBMB Life
  
  Volume: 64 Pages: 450-454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Pharmaceutical aspects of the recombinant human serum albumin dimer: Structural characteristics, biological properties, and medical applications.2012
- Author(s)
  Taguchi K, Giam Chuang VT, Maruyama T, Otagiri M. 2012:
- Journal Title
  
  J Pharm Sci.
  
  Volume: 101 Pages: 3033-3046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043
[Journal Article] Liposome-encapsulated hemoglobin (hemoglobin-vesicle) is not transferred from mother to fetus at the late stage of pregnancy in the rat model.2012
- Author(s)
  Kaga M, Li H, Ohta H, Taguchi K, Ogaki S, Izumi H, Inagaki M, Tsuchiya S, Okamura K, Otagiri M, Sakai H, and Yaegashi N.
- Journal Title
  
  Life Sci.
  
  Volume: 91 Issue: 11-12 Pages: 420-8
- DOI
  10.1016/j.lfs.2012.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24790159
[Journal Article] Characterization of the hepatic cellular uptake of α1-acid glycoprotein(AGP), part 1 : a peptide moiety of human AGP is recognized by the hemoglobinβ-chain on mouse liver parenchymal cells2012
- Author(s)
  Nishi K, Komori H, Kikuchi M, Uehara N, Fukunaga N, Matsumoto K, Watanabe H, Nakajou K, Misumi S, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  J. Pharm. Sci
  
  Volume: 101 Pages: 1599-1606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate.2012
- Author(s)
  Miyamoto Y, Iwao Y, Mera K, Watanabe H, Kadowaki D, Ishima Y, Chuang VT, Sato K, Otagiri M, Maruyama T.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 84 Pages: 1207-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Characterization of hepatic cellular uptake of α1-acid glycoprotein (AGP), part 2: Involvement of hemoglobin β-chain on plasma membranes in the uptake of human AGP by liver parenchymal cells2012
- Author(s)
  Komori H, Nishi K, Uehara N, Watanabe H, Shuto T, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 101 Pages: 1607-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] α1-acid glycoprotein up-regulates CD163 via TLR4/CD14 pathway: possible protection against hemolysis-induced oxidative stress.2012
- Author(s)
  Komori H, Watanabe H, Shuto T, Kodama A, Maeda H, Watanabe K, Kai H, Otagiri M, Maruyama T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Issue: 36 Pages: 30688-700
- DOI
  10.1074/jbc.m112.353771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-23790188, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Elucidation of the therapeutic enhancer mechanism of poly-S-nitrosated human serum albumin against multidrug-resistant tumor in animal models.2012
- Author(s)
  Ishima Y
- Journal Title
  
  J Control Release.
  
  Volume: 164 Issue: 1 Pages: 1-7
- DOI
  10.1016/j.jconrel.2012.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Pharmaceutical aspects of the recombinant human serum albumin dimer: Structural characteristics, biological properties, and medical applications.2012
- Author(s)
  Taguchi K, Giam Chuang VT, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 101 Pages: 3033-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Characterization of the hepatic cellular uptake of α(1)-acid glycoprotein (AGP), part 1: A peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells2012
- Author(s)
  Nishi K, Komori H, Kikuchi M, Uehara N, Fukunaga N, Matsumoto K, Watanabe H, Nakajou K, Misumi S, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 101 Pages: 1599-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Effect of acetaminophen on progression of renal damage in adenine induced renal failure model rat.2012
- Author(s)
  Kadowaki D, Sumikawa S, Arimizu K, Taguchi K, Kitamura K, Ishitsuka Y, Narita Y, Irie T, Maruyama T, Otagiri M, Hirata S
- Journal Title
  
  Life Sci.
  
  Volume: 91 Issue: 25-26 Pages: 1304-1308
- DOI
  10.1016/j.lfs.2012.09.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590136, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-24790159
[Journal Article] Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain in A and Ill B.2012
- Author(s)
  Kaneko K, Chuang VT, Ito T, Suenaga A, Watanabe H, Maruyama T, Otagiri M.Pharmazie.
- Journal Title
  
  Pharmazie.
  
  Volume: 67 Pages: 414-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390043
[Journal Article] S-Guanylation of human serum albumin is a unique posttranslational modification and results in a novel class of antibacterial agents2012
- Author(s)
  Ishima Y, Hoshino H, Shinagawa T, Watanabe K, Akaike T, Sawa T, Kragh-Hansen U, Kai T, Watanabe H, Maruyama T, and Otagiri M
- Journal Title
  
  J. Pharm. Sci
  
  Volume: 101 Issue: 9 Pages: 3222-3229
- DOI
  10.1002/jps.23143
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23651239, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-ORGANIZER-20117001
[Journal Article] Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats.2012
- Author(s)
  Kadowaki D, Sumikawa S, Arimizu K, Taguchi K, Kitamura K, Ishitsuka Y, Narita Y, Irie T, Chuang VT, Maruyama T, Otagiri M, Hirata S.
- Journal Title
  
  Life Sci
  
  Volume: 91 Pages: 1304-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate.2012
- Author(s)
  Yohei Miyamoto, Yasunori Katsumi Mera, Hiroshi Watanabe, Daisuke Kadowaki, Yu Ishima, Victor Tuan Giam Chuang, Keizo Sato, Masaki Otagiri, Toru Maruyama.
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 84 Issue: 9 Pages: 1207-1214
- DOI
  10.1016/j.bcp.2012.07.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05768, KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23790187, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076, KAKENHI-PROJECT-24790160
[Journal Article] Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants.2012
- Author(s)
  Iwao Y, Ishima Y, Yamada J, Noguchi T, Kragh-Hansen U, Mera K, Honda D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  IUBMB Life
  
  Volume: 64 Pages: 450-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Characterization of the hepatic cellular uptake of α(1) -acid glycoprotein (AGP), part 1: A peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells.2012
- Author(s)
  Nishi K, Komori H, Kikuchi M, Uehara N, Fukunaga N, Matsumoto K, Watanabe H, Nakajou K, Misumi S, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 101 Pages: 1599-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Pharmaceutical aspects of the recombinant human serum albumin dimer: structural characteristics, biological properties, and medical applications.2012
- Author(s)
  Taguchi K, Chuang VT, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 101 Issue: 9 Pages: 3033-46
- DOI
  10.1002/jps.23181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24790159
[Journal Article] Structural insights into differences in drug binding selectivity between two forms of human {alpha}1-acid glycoprotein genetic variants, the A and FI^*S forms.2011
- Author(s)
  Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H, Suenaga A, Maruyama T, Yamagata Y, Curry S, Otagiri M.
- Journal Title
  
  J Biol Chem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy.2011
- Author(s)
  Kugimiya T, Jono H, Saito S, Maruyama T, Kadowaki D, Misumi Y, Hoshii Y, Tasaki M, Su Y, Ueda M, Obayashi K, Shono M, Otagiri M, Ando Y.
- Journal Title
  
  Lab Invest.
  
  Volume: 91 Pages: 1219-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Toxicodynamic evaluation of a cisplatin-chondroitin sulfate complex using a perfused kidney and human proximal tubular cells2011
- Author(s)
  Zhang JS, Kadowaki D, Nonoguchi H, Hirata S, Seo H, Imai T, Suenaga A, Giam Chuang VT, Otagiri M
- Journal Title
  
  Ren Fail
  
  Volume: 33 Pages: 609-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Parathyroidectomy markedly reduces oxidative stress in a patient with primary hyperparathyroidism2011
- Author(s)
  Tanaka M, Tokunaga K, Maruyama T, Otagiri M, Tominaga Y, Itoh K, Matsushita K, Komaba H, Fukagawa M
- Journal Title
  
  Ther Apher Dial
  
  Volume: 15 Pages: 38-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 26 Pages: 2498-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury2011
- Author(s)
  Furukawa M, Tanaka R, Chuang VT, Ishima Y, Taguchi K, Watanabe H, Maruyama T, Otagiri M
- Journal Title
  
  J Control Release
  
  Volume: 154 Pages: 189-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Vitamin D receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism.2011
- Author(s)
  Tanaka M, Tokunaga K, Komaba H, Itoh K, Matsushita K, Watanabe H, Kadowaki D, Maruyama T, Otagiri M, Fukagawa M.
- Journal Title
  
  Ther Apher Dial. 15
  
  Pages: 129-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 39 Pages: 484-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Vitamin D receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism2011
- Author(s)
  Tanaka M, Tokunaga K, Komaba H, Itoh K, Matsushita K, Watanabe H, Kadowaki D, Maruyama T, Otagiri M, Fukagawa M
- Journal Title
  
  Ther Apher Dial
  
  Volume: 15 Pages: 161-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] An autoantibody against N (ε)-(carboxyethyl) lysine (CEL) :possible involvement in the removal of CEL-modified proteins by macrophages2011
- Author(s)
  Mera K, Nagai R, Takeo K, Izumi M, Maruyama T, Otagiri M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 420-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Biological characteristics of two lysines on human serum albumin in the high-affinity binding of 4Z, 15Z-bilirubin-LXα revealed by phage display2011
- Author(s)
  Minomo A, Ishima y, Kragh-Hansen U, Chuang VT, Uchida M, Taguchi K, Watanabe H, Maruyama T, Morioka H, Otagiri M
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 4100-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells.2011
- Author(s)
  Taguchi K, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Rev.
  
  Volume: 43 Pages: 362-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Vitamin d receptor activator reduces oxidative stress in hemodialys is patients with secondary hyperparathyroidism.2011
- Author(s)
  Tanaka M,, Tokunaga K,, Komaba H,, Itoh K,, Matsushita K, Watanabe H,, Kadowaki D, Maruyama T,, Otagiri M,, Fukagawa M.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 161-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Structural insights into differences in drug binding selectivity between two forms of human {alpha}1-acid glycoprotein genetic variants, the A and Fl^* S forms.2011
- Author(s)
  Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H, Suenaga A, Maruyama T, Yamagata Y, Curry S, Otagiri M.
- Journal Title
  
  J Biol Chem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding2011
- Author(s)
  Kaneko K, Chuang VT, Minomo A, Yamasaki K, Bhagavan NV, Maruyama T, Otagiri M
- Journal Title
  
  IUBMB Life
  
  Volume: 63 Pages: 277-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Structural insights into differences in drug binding selectivity between two forms of human alphal-acid glycoprotein genetic variants, the A and F1*S forms.2011
- Author(s)
  Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H, Suenaga A, Maruyama T, Yamagata Y, Curry S, Otagiri M.
- Journal Title
  
  J Biol Chem. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Update on the pharmacokinetics and redox properties of protein-bound uremic toxins2011
- Author(s)
  Watanabe H, Miyamoto Y, Otagiri M, Maruyama T
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Pages: 3682-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Update on the pharmacokinetics and redox properties of protein-bound uremic toxins.2011
- Author(s)
  Watanabe H, Miyamoto Y, Otagiri M,Maruyama T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 3682-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] An autoantibody against N(ε)-(carboxyethyl)lysine(CEL) : Possible involvement in the removal of CEL-modified proteins by macrophages.2011
- Author(s)
  Mera K,, Nagai R,, Takeo K, Izumi M,, Maruyama T,, Otagiri M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury.2011
- Author(s)
  Furukawa M, Tanaka R, Chuang VT, Ishima Y, Taguchi K, Watanabe H, Maruyama T, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 154 Pages: 189-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells.2011
- Author(s)
  Taguchi K, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Rev.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] New insight into the redox properties of uremic solute indoxyl sulfate as a pro-and anti-oxidant.2011
- Author(s)
  Miyamoto Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 129-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Fluid resuscitation with hemoglobin-vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharmacol Exp Ther. 337
  
  Pages: 201-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney.2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Spectroscopic studies of interactions of chondroitin sulfates with cisplatin.2011
- Author(s)
  Zhang JS, Anraku M, KadowakiD, Imai T, Suenaga A, Odai A, Otagiri M
- Journal Title
  
  Carbohydr Res.
  
  Volume: 346 Pages: 631-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 337 Pages: 201-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Characterization of the hepatic cellular uptake of α_1-acid glycoprotein (AGP), Part 1 : A peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse liver parenchymal cells2011
- Author(s)
  西弘二、小森久和
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 101 Issue: 4 Pages: 1599-1606
- DOI
  10.1002/jps.23015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04581, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-23790188, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 26 Pages: 2498-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] An autoantibody against N(ε)-(carboxyethyl)lysine (CEL) : Possible involvement in the removal of CEL-modified proteins by macrophages.2011
- Author(s)
  Mera K, Nagai R, Takeo K, Izumi M, Maruyama T, Otagiri M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells2011
- Author(s)
  Taguchi K, Maruyama T, Otagiri M
- Journal Title
  
  Drug Metab Rev
  
  Volume: 43 Pages: 362-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney.2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant.2011
- Author(s)
  Miyamoto Y,, Watanabe H,, Otagiri M,, Maruyama T.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 129-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Parathyroidectomy markedly reduces oxidative stress in a patient with primary hyperparathyroidism.2011
- Author(s)
  Tanaka M, Tokunaga K, Maruyama T, Otagiri M, Tominaga Y, Itoh K, Matsushita K, Komaba H, Fukagawa M
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 38-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Fluid Resuscitation with Hemoglobin Vesicles Prevents Escherichiacoli Growth via Complement Activation in a Hemorrhagic Shock Rat Model.2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 337 Pages: 201-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 39 Pages: 484-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Repeated injection of high doses of hemoglobin-encapsulated liposomes (hemoglobin vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 39 Pages: 484-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Update on the pharmacokinetics and redox properties of protein-bound uremic toxins2011
- Author(s)
  Watanabe H, Miyamoto Y, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharm Sci
  
  Pages: 3682-3695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2011
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] S-Nitrosated Human Serum Albumin Dimer is not only a Novel Anti-Tumor Drug but also a Potentiator for Anti-Tumor Drugs with Augmented EPR Effects. f2011
- Author(s)
  Ishima Y, Chen D, Fang J, Maeda H, Minomo A, Kragh-Hansen U, Kai T, Maruyama T, Otagiri M
- Journal Title
  
  Bioconjug Chem
  
  Volume: 23 Pages: 264-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant.2011
- Author(s)
  Miyamoto Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 129-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Fluid Resuscitation with Hemoglobin Vesicles Prevents Escherichiacoli Growth via Complement Activation in a Hemorrhagic Shock Rat Model.2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 337 Pages: 201-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury2011
- Author(s)
  Furukawa M, Tanaka R, Chuang VT, Ishima Y, Taguchi K, Watanabe H, Maruyama T, Otagiri M
- Journal Title
  
  J. Control. Release
  
  Volume: 154 Pages: 189-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy2011
- Author(s)
  Kugimiya T, Jono H, Saito S, Maruyama T, Kadowaki D, Misumi Y, Hoshii Y, Tasaki M, Su Y, Ueda M, Obayashi K, Shono M, Otagiri M, Ando Y
- Journal Title
  
  Lab Invest
  
  Volume: 91 Pages: 1219-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Vitamin d receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism.2011
- Author(s)
  Tanaka M, Tokunaga K, Komaba H, Itoh K, Matsushita K, Watanabe H, Kadowaki D, Maruyama T, Otagiri M, Fukagawa M.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 161-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Biological characteristics of two lysines on human serum albumin in the high-affinity binding of 4Z,15Z-bilirubin-IXα revealed by phage display.2011
- Author(s)
  Minomo A, Ishima Y, Kragh-Hansen U, Chuang VT, Uchida M, Taguchi K, Watanabe H, Maruyama T, Morioka H, Otagiri M.
- Journal Title
  
  FEBS J.
  
  Volume: 278 Pages: 4100-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney.2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T.
- Journal Title
  
  Nephrol Dial Transplant. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Spectroscopic studies of interactions of chondroitin sulfates with cisplatin.2011
- Author(s)
  Zhang JS, Anraku M, Kadowaki D, Imai T, Suenaga A, Odani A, Otagiri M.
- Journal Title
  
  Carbohydr Res.
  
  Volume: 346 Pages: 631-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Repeated injection of high doses of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.2011
- Author(s)
  Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos. 39
  
  Pages: 484-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Characterization of the hepatic cellular uptake of α_1-acid glycoprotein (AGP), Part 2 : Involvement of the hemoglobin β-chain on plasma membranes in the uptake of human AGP by liver parenchymal cells2011
- Author(s)
  小森久和
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 101 Issue: 4 Pages: 1607-1615
- DOI
  10.1002/jps.22804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04581, KAKENHI-PROJECT-21590054, KAKENHI-PROJECT-23659088, KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-24659076
[Journal Article] Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin.2011
- Author(s)
  Ishima Y, Yoshida F, Kragh-Hansen U, Watanabe K, Katayama N, Nakajou K, Akaike T, Kai T, Maruyama T, Otagiri M.
- Journal Title
  
  Free Radic Res.
  
  Volume: 45 Pages: 1196-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Vitamin d receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism.2011
- Author(s)
  Tanaka M, Tokunaga K, Komaba H, Itoh K, Matsushita K, Watanabe H, Kadowaki D, Maruyama T, Otagiri M, Fukagawa M.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 161-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding2011
- Author(s)
  Kaneko K, Chuang VT, Minomo A, Yamasaki K, Bhagavan NV, Maruyama T, Otagiri M
- Journal Title
  
  IUBMB Life
  
  Volume: 63 Pages: 277-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Spectroscopic studies of interactions of chondroitin sulfates with cisplatin2011
- Author(s)
  Zhang JS, Anraku M, KadowakiD, Imai T, Suenaga A, Odai A, Otagiri M
- Journal Title
  
  Carbohydr Res
  
  Volume: 346 Pages: 631-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity2011
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Pages: 775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin2011
- Author(s)
  Ishima Y, Yoshlda F, Kragh-Hansen U, Watanabe K, Katayama N, Nakajou K, Akaike T, Kai T, Maruyama T, Otagiri M
- Journal Title
  
  Free Radic Res
  
  Volume: 45 Pages: 1196-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant2011
- Author(s)
  Miyamoto Y, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Ther Apher Dial
  
  Volume: 15 Pages: 129-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.2011
- Author(s)
  Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H, Suenaga A, Maruyama T, Yamagata Y, Curry S,Otagiri M
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 14427-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney.2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 26 Pages: 2498-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2011
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci. 100
  
  Pages: 775-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 337 Pages: 201-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Vitamin D receptor activator reduces oxidative stress in hemodialysis patients with secondary hyperparathyroidism.2011
- Author(s)
  Tanaka M, Tokunaga K, Komaba H, Itoh K, Matsushita K, Watanabe H, Kadowaki D, Maruyama T, Otagiri M, Fukagawa M.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 161-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients2011
- Author(s)
  Anraku M, Takeuchi K, Watanabe H, Kadowaki D, Kitamura K, Tomita K, Kuniyasu A, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Pages: 3968-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Structural insights into differences in drug binding selectivity between two forms of human{alpha}1-acid glycoprotein genetic variants, the A and F1*S forms.2011
- Author(s)
  Nishi K,, Ono T,, Nakamura T,, Fukunaga N,, Izumi M,, Watanabe H,, Suenaga A,, Maruyama T,, Yamagata Y,, Curry S, Otagiri M.
- Journal Title
  
  J Biol Chem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Structural insights into differences in drug-binding selectivity between two forms of human alphal-acid glycoprotein genetic variants, the A and F1^*S forms2011
- Author(s)
  Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H, Suenaga A, Maruyama T, Yamagata Y, Curry S, Otagiri M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 14427-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney.2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding.2011
- Author(s)
  Kaneko K, Chuang VT, Minomo A, Yamasaki K, Bhagavan NV, Maruyama T, Otagiri M
- Journal Title
  
  IUBMB Life.
  
  Volume: 63 Pages: 277-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] An autoantibody against N(ε)-(carboxyethyl)lysine (CEL) : Possible involvement in the removal of CEL-modified proteins by macrophages.2011
- Author(s)
  Mera K, Nagai R, Takeo K, Izumi M, Maruyama T, Otagiri M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney2011
- Author(s)
  Miyamoto Y, Watanabe H, Noguchi T, Kotani S, Nakajima M, Kadowaki D, Otagiri M, Maruyama T
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 26 Pages: 2498-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant.2011
- Author(s)
  Miyamoto Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 15 Pages: 129-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] S-Nitrosated Human Serum Albumin Dimer is not only a Novel Anti-Tumor Drug but also a Potentiator for Anti-Tumor Drugs with Augmented EPR Effects.ｆ2011
- Author(s)
  Ishima Y, Chen D, Fang J, Maeda H, Minomo A, Kragh-Hansen U, Kai T, Maruyama T, Otagiri M.
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 23 Pages: 264-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] An autoantibody against N(ε)-(carboxyethyl)lysine (CEL): possible involvement in the removal of CEL-modified proteins by macrophages.2011
- Author(s)
  Mera K, Nagai R, Takeo K, Izumi M, Maruyama T, Otagiri M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 407 Pages: 420-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Fluid Resuscitation with Hemoglobin Vesicles Prevents Escherichia coli Growth via Complement Activation in a Hemorrhagic Shock Rat Model.2011
- Author(s)
  Taguchi K, Ogaki S, Watanabe H, Kadowaki.D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 337 Pages: 201-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Spectroscopic studies of interactions of chondroitin sulfates with cisplatin.2011
- Author(s)
  Zhang JS, Anraku M, Kadowaki D, Imai T, Suenaga A, Odani A, Otagiri M.
- Journal Title
  
  Carbohydr Res.
  
  Volume: 346 Pages: 631-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients.2011
- Author(s)
  Anraku M, Takeuchi K, Watanabe H, Kadowaki D, Kitamura K, Tomita K, Kuniyasu A, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 3968-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients.2011
- Author(s)
  Anraku M, Takeuchi K, Watanabe H, Kadowaki D, Kitamura K, Tomita K, Kuniyasu A, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Toxicodynamic evaluation of a cisplatin-chondroitin sulfate complex using a perfused kidney and human proximal tubular cells.2011
- Author(s)
  Zhang JS, Kadowaki D, Nonoguchi H, Hirata S, Seo H, Imai T, Suenaga A, Giam Chuang VT, Otagiri M.
- Journal Title
  
  Ren Fail.
  
  Volume: 33 Pages: 609-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659088
[Journal Article] Cellular uptake mechanisms and responses to NO transferred from mono- and poly-S-nitrosated human serum albumin2011
- Author(s)
  Yu Ishima., et al
- Journal Title
  
  Free Radical Research
  
  Volume: 45 Issue: 10 Pages: 1196-1206
- DOI
  10.3109/10715762.2011.606814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21390097, KAKENHI-PROJECT-21591000, KAKENHI-PROJECT-22790162, KAKENHI-PROJECT-23390142, KAKENHI-PROJECT-23651239
[Journal Article] Albumin fusion of thioredoxin-the production and evaluation, of its biological activity for potential therapeutic applications.2010
- Author(s)
  Ikuta S, Chuang VT, Ishima Y, Nakajou K, Furukawa M, Watanabe H, Maruyama T, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 147 Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2010
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] One-step preparation of S-nitrosated human serum albumin with high biological activities.2010
- Author(s)
  Ishima Y, Hiroyama S, Kragh-Hansen U, Maruyama T, Sawa T, Akaike T, Kai T, Otagiri M.
- Journal Title
  
  Nitric Oxide.
  
  Volume: 23 Pages: 121-7
- NAID
  120002971552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions.2010
- Author(s)
  Miyamoto Y, Iwao Y, Tasaki Y, Sato K, Ishima Y, Watanabe H, Kadowaki D, Maruyama T, Otagiri M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 2816-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Albumin fusion of thioredoxin-the production and evaluation of its biological activity for potential therapeutic applications.2010
- Author(s)
  Ikuta S, Chuang VTG, Ishima Y, Nakajou K, Furukawa M, Watanabe H, Maruyama T, Otagiri M.
- Journal Title
  
  J Control Release. 147
  
  Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Enhancement of dissolution and bioavailability of flurbiprofen by low molecular weight chitosans.2010
- Author(s)
  Anraku M, Arahira M, Mady FM, Khaled KA, Yamasaki K, Seo H, Imai T, Otagiri M.
- Journal Title
  
  Pharmazie.
  
  Volume: 65 Pages: 461-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] One-step preparation of S-nitrosated human serum albumin with high biological activities.2010
- Author(s)
  Ishima Y, Hiroyama S, Kragh-Hansen U, Maruyama T, Sawa T, Akaike T, Kai T, Otagiri M.
- Journal Title
  
  Nitric Oxide.
  
  Volume: 23 Pages: 121-7
- NAID
  120002971552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] The roles of oligosaccharide moieties in structural and functional properties2010
- Author(s)
  Nishi K, Fukunaga N, Ono T, Akuta T, Yumita N, Watanabe H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 25 Pages: 200-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Receptor-mediated uptake of humanα1-acid glycoprotein into liver parenchymal cells in mice2010
- Author(s)
  Matsumoto K, Nishi K, Kikuchi M, Watanabe H, Nakajou K, Komori H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 25 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Receptor-mediated uptake of human?acid glycoprotein into liver parenchymal cells in mice.2010
- Author(s)
  Matsumoto K, Nishi K, Kikuchi M, Watanabe H, Nakajou K, Komori H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet. 25
  
  Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions.2010
- Author(s)
  Miyamoto Y, Iwao Y, Tasaki Y, Sato K, Ishima Y, Watanabe H, Kadowaki D, Maruyama T, Otagiri M.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 2816-2820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Construction of an expression system for human alpha(1)-acid glycoprotein in E.coli : The roles of oligosaccharide moieties in structural and functional properties.2010
- Author(s)
  Nishi K, Fukunaga N, Ono T, Akuta T, Yumita N, Watanabe H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 200-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.2010
- Author(s)
  Tsujimoto M, Higuchi K, Shima D, Yokota H, Furukubo T, Izumi S, Yamakawa T, Otagiri M, Hirata S, Takara K, Nishiguchi K.
- Journal Title
  
  J Pharm Pharmacol.
  
  Volume: 62 Pages: 133-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2010
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin vesicles, can be safely used under conditions of hepatic impairment.2010
- Author(s)
  Taguchi K, Miyasato M, Ujihira H, Watanabe H, Kadowaki D, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  Toxicol Appl Pharmacol.
  
  Volume: 248 Pages: 234-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin-vesicles, can be safely used under conditions of hepatic impairment.2010
- Author(s)
  Taguchi K, Miyasato M, Ujihira H, Watanabe H, Kadowaki D, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  Toxicol Appl Pharmacol. 248
  
  Pages: 234241-234241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions.2010
- Author(s)
  Miyamoto Y, Iwao Y, Tasaki Y, Sato K, Ishima Y, Watanabe H, Kadowaki D, Maruyama T, Otagiri M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 2816-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Enhancement of the aqueous solubility and masking the bitter taste of famotidine using drug/SBE-beta-CyD/povidone K30 complexation approach.2010
- Author(s)
  Mady FM, Abou-Taleb AE, Khaled KA, Yamasaki K, Iohara D, Ishiguro T, Hirayama F, Uekama K, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 99 Pages: 4285-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics.2010
- Author(s)
  Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 145 Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Construction of an expression system for human?acid glycoprotein in E.coli : the role of oligosaccharide moieties on structural and functional properties.2010
- Author(s)
  Nishi K, Fukunaga N, Ono T, Akuta T, Yumita N, Watanabe H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet. 25
  
  Pages: 200-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats.2010
- Author(s)
  Anraku M, Michihara A, Yasufuku T, Akasaki K, Tsuchiya D, Nishio H, Maruyama T, Otagiri M, Maezaki Y, Kondo Y, Tomida H.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 33 Pages: 1994-8
- NAID
  130000402332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics.2010
- Author(s)
  Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 145 Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Construction of an expression system for human alpha(1)-acid glycoprotein in E.coli : The roles of oligosaccharide moieties in structural and functional properties.2010
- Author(s)
  Nishi K, Fukunaga N, Ono T, Akuta T, Yumita N, Watanabe H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 200-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice.2010
- Author(s)
  Matsumoto K, Nishi K, Kikuchi M, Watanabe H, Nakajou K, Komori H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 101-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.2010
- Author(s)
  Tsujimoto M, Higuchi K, Shima D, Yokota H, Furukubo T, Izumi S, Yamakawa T, Otagiri M, Hirata S, Takara K, Nishiguchi K.
- Journal Title
  
  J Pharm Pharmacol.
  
  Volume: 62 Pages: 133-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Albumin fusion of thioredoxin--the production and evaluation of its biological activity for potential therapeutic applications.2010
- Author(s)
  Ikuta S, Chuang VT, Ishima Y, Nakajou K, Furukawa M, Watanabe H, Maruyama T, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 147 Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Superior plasma retention of a cross-linked human serum albumin dimer in nephrotic rats as a new type of plasma expander.2010
- Author(s)
  Taguchi K, Urata Y, Anraku M, Watanabe H, Kawai K, Komatsu T, Tsuchida E, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Pages: 2124-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Superior plasma retention of a cross-linked human serum albumin dimer in nephrotic rats as a new type of plasma expander.2010
- Author(s)
  Taguchi K, Urata Y, Anraku M, Watanabe H, Kawai K, Komatsu T, Tsuchida E, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos. 38
  
  Pages: 2124-2129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Receptor-mediated uptake of human alphal-acid glycoprotein into liver parenchymal cells in mice.2010
- Author(s)
  Matsumoto K, Nishi K, Kikuchi M, Watanabe H, Nakajou K, Komori H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 101-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Enhancement of dissolution and bioavailability of flurbiprofen by low molecular weight chitosans.2010
- Author(s)
  Anraku M, Arahira M, Mady FM, Khaled KA, Yamasaki K, Seo H, Imai T, Otagiri M.
- Journal Title
  
  Pharmazie.
  
  Volume: 65 Pages: 461-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] One-step preparation of S-nitrosated human serum albumin with high biological activities.2010
- Author(s)
  Ishima Y, Hiroyama S, Kragh-Hansen U, Maruyama T, Sawa T, Akaike T, Kai T, Otagiri M.
- Journal Title
  
  Nitric Oxide.
  
  Volume: 23 Pages: 121-7
- NAID
  120002971552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics.2010
- Author(s)
  Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M.
- Journal Title
  
  J Control Release. 145
  
  Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics.2010
- Author(s)
  Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 145 Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The antioxidative and antilipidemic effects of different molecular weight chitosans in metabolic syndrome model rats.2010
- Author(s)
  Anraku M, Michihara A, Yasufuku T, Akasaki K, Tsuchiya D, Nishio H, Maruyama T, Otagiri M, Maezaki Y, Kondo Y, Tomida H.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 33 Pages: 1994-8
- NAID
  130000402332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Albumin fusion of thioredoxin-the production and evaluation of its biological activity for potential therapeutic applications.2010
- Author(s)
  Ikuta S, Chuang VT, Ishima Y, Nakajou K, Furukawa M, Watanabe H, Maruyama T, Otagiri M.
- Journal Title
  
  J Control Release.
  
  Volume: 147 Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Enhancement of the aqueous solubility and masking the bitter taste of famotidine using drug/SBE-beta-CyD/povidone K30 complexation approach.2010
- Author(s)
  Mady FM, Abou-Taleb AE, Khaled KA, Yamasaki K, Iohara D, Ishiguro T, Hirayama F, Uekama K, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 99 Pages: 4285-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Evaluation of carboxymethyl-beta-cyclodextrin with acid function : improvement of chemical stability, oral bioavailability and bitter taste of famotidine.2010
- Author(s)
  Mady FM, Abou-Taleb AE, Khaled KA, Yamasaki K, lohara D, Taguchi K, Anraku M, Hirayama F, Uekama K, Otagiri M.
- Journal Title
  
  Int J Pharm.
  
  Volume: 397 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Superior plasma retention of a cross-linked human serum albumin dimer in nephrotic rats as a new type of plasma expander.2010
- Author(s)
  Taguchi K, Urata Y, Anraku M, Watanabe H, Kawai K, Komatsu T, Tsuchida E, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Pages: 2124-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Receptor-mediated uptake of human alpha1-acid glycoprotein into liver parenchymal cells in mice.2010
- Author(s)
  Matsumoto K, Nishi K, Kikuchi M, Watanabe H, Nakajou K, Komori H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 101-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Construction of an expression system for human alpha(1)-acid glycoprotein in E.coli : The roles of oligosaccharide moieties in structural and functional properties.2010
- Author(s)
  Nishi K, Fukunaga N, Ono T, Akuta T, Yumita N, Watanabe H, Kadowaki D, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 25 Pages: 200-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Journal Article] Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupffer cell phagocyte activity.2010
- Author(s)
  Taguchi K, Miyasato M, Watanabe H, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 100 Pages: 775-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics2010
- Author(s)
  Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M
- Journal Title
  
  J. Control. Release
  
  Volume: 145 Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Hepatically-metabolize and -excreted artificial oxygen carrier hemoglobin vesicles, can be safely used under conditions of hepatic impairment.2010
- Author(s)
  Taguchi K, Miyasato M, Ujihira H, Watanabe H, Kadowaki D, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  Toxicol Appl Pharmacol.
  
  Volume: 248 Pages: 234-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions.2010
- Author(s)
  Miyamoto Y, Iwao Y, Tasaki Y, Sato K, Ishima Y, Watanabe H, Kadowaki D, Maruyama T, Otagiri M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 2816-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Hepatically-metabolized and -excreted artificial oxygen carrier, hemoglobin vesicles, can be safely used under conditions of hepatic impairment.2010
- Author(s)
  Taguchi K, Miyasato M, Ujihira H, Watanabe H, Kadowaki D, Sakai H, Tsuchida E, Horinouchi H, Kobayashi K, Maruyama T, Otagiri M.
- Journal Title
  
  Toxicol Appl Pharmacol.
  
  Volume: 248 Pages: 234-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Evaluation of carboxymethyl-beta-cyclodextrin with acid function : improvement of chemical stability, oral bioavailability and bitter taste of famotidine.2010
- Author(s)
  Mady FM, Abou-Taleb AE, Khaled KA, Yamasaki K, Iohara D, Taguchi K, Anraku M, Hirayama F, Uekama K, Otagiri M.
- Journal Title
  
  Int J Pharm.
  
  Volume: 397 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390177
[Journal Article] Superior plasma retention of a cross-linked human serum albumin dimer in nephrotic rats as a new type of plasma expander.2010
- Author(s)
  Taguchi K, Urata Y, Anraku M, Watanabe H, Kawai K, Komatsu T, Tsuchida E, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Pages: 2124-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin-vesicles as an artificial oxygen carrier.2009
- Author(s)
  Taguchi K, Urata Y, Anraku M, Maruyama T, Watanabe H, Sakai H, Horinouchi H, Kobayashi K, Tsuchida E, Kai T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos. 37
  
  Pages: 1456-1463
- NAID
  130004639499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] A site-directed mutagenesis study of drug-binding selectivity in genetic variants of human alpha (1)-acid glycoprotein.2009
- Author(s)
  Nishi K, Ueno M, Murakami Y, Fukunaga N, Akuta T, Kadowaki D, Watanabe H, Suenaga A, Maruyama T, Otagiri M.
- Journal Title
  
  J Pharm Sci. 98
  
  Pages: 4316-4326
- NAID
  130005024241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Study on binding of drug to serum protein2009
- Author(s)
  Otagiri M
- Journal Title
  
  Yakugaku Zasshi 129(4)
  
  Pages: 413-25
- NAID
  110007230199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Altered chain-length and glycosylation modify the pharmacokinetics of human serum albumin2009
- Author(s)
  Iwao Y, Hiraike M, Kragh-Hansen U, Kawai K, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  Biochimica et Biophysica Acta -Proteins and Proteomics 1794(4)
  
  Pages: 634-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Pharmaceutically important pre-and posttranslational modifications on human serum albumin2009
- Author(s)
  Otagiri M, Chuang VTG
- Journal Title
  
  Biological and Pharmaceutical Bulletin 32(4)
  
  Pages: 527-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Hemoglobin vesicles, polyethylene glycol (PEG) ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice.2009
- Author(s)
  Taguchi K, Urata Y, Anraku M, Watanabe H, Kadowaki D, Sakai H, Horinouchi H, Kobayashi K, Tsuchida E, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Dispos. 37
  
  Pages: 2197-2203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model2009
- Author(s)
  Taguchi K, Maruyama T, Iwao Y, Sakai H, Kobayashi K, Horinouchi H, Tsuchida E, Kai T, Otagiri M
- Journal Title
  
  J Controlled Release (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] A site-directed mutagenesis study of drug-binding selectivity in genetic variants of humanα1-acid glycoprotein2009
- Author(s)
  Nishi K, Ueno M, Murakami Y, Fukunaga N, Akuta T, Kadowaki D, Watanabe H, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  J. Pharm. Sci
  
  Volume: 98 Pages: 4316-4326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Antioxidant effects of a dietary supplement : Reduction of indices of oxidative stress in normal subjects by water-soluble chitosan2009
- Author(s)
  Anraku M, Fujii T, Furutani N, Kadowaki D, Maruyama T, Otagiri M, Gebicki JM, Tomida H
- Journal Title
  
  Food and Chemical Toxicology 47(1)
  
  Pages: 104-9
- NAID
  10024330157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Subdomain IIIA of dog albumin contains a binding site similar to site II of human albumin2008
- Author(s)
  Kaneko K, Fukuda H, Chuang VTG, Yamasaki K, Kawahara K, Nakayama H, Suenaga A, Maruyama T, Otagiri M
- Journal Title
  
  Drug Metab Disposition 36(1)
  
  Pages: 81-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Effects of uremic serum and uremic toxins on hepatic uptake of digoxin2008
- Author(s)
  Tsujimoto M, Kinoshita Y, Hirata S, Otagiri M, Ohtani H, Sawada Y
- Journal Title
  
  Ther Drug Monit 30(5)
  
  Pages: 576-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Effect of intravenous iron administration frequency on AOPP and inflammatory biomarkers in chronic hemodialysis patients : A pilot study2008
- Author(s)
  Anraku M, Kitamura K, Shintomo R, Takeuchi K, Ikeda H, Nagano J, Ko T, Mera K, Tomita K, Otagiri M
- Journal Title
  
  Clin Biochem 41(14-15)
  
  Pages: 1168-74
- NAID
  120005952925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Design and evaluation of S-nitrosylated human serum albumin as a novel anticancer drug2008
- Author(s)
  Katayama N, Nakajou K, Komori H, Uchida K, Yokoe J, Yasui N, Yamamoto H, Kai T, Sato M, Nakagawa T, Takeya M, Maruyama T, Otagiri M
- Journal Title
  
  J Pharmacol Exp Ther 325(1)
  
  Pages: 69-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products2008
- Author(s)
  Iwao Y, Nakajou K, Nagai R, Kitamura K, Anraku M, Maruyama T, Otagiri M
- Journal Title
  
  American Journal of Physiology-Renal Physiology 295(6)
- NAID
  120005952926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding2008
- Author(s)
  Ishima Y, Akaike T, Kragh-Hansen U, Hiroyama S, Sawa T, Suenaga A, Maruyama T, Kai T, Otagiri M
- Journal Title
  
  J Biol Chem 283(50)
  
  Pages: 34966-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Antioxidant protection of human serum albumin by chitosan2008
- Author(s)
  Anraku M, Kabashima M, Namura H, Maruyama T, Otagiri M, Gebicki JM, Furutani N, Tomida H
- Journal Title
  
  Int J Biol Macromol 43(2)
  
  Pages: 159-64
- NAID
  120005952924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Structural and ligand-binding properties of serum albumin species interacting with a biomembrane interface2007
- Author(s)
  Kosa T, Nishi K, Maruyama T, Sakai N, Yonemura N, Watanabe H, Suenaga A, Otagiri M
- Journal Title
  
  J Pharm Sci 96(11)
  
  Pages: 3117-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Investigation of pathways of advanced glycation end-products accumulation in macrophages2007
- Author(s)
  Nagai R, Fujiwara Y, Mera K, Otagiri M
- Journal Title
  
  Molecular Nutrition and Food Research 51(4)
  
  Pages: 462-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] The role of N-acetyl-methioninate as a new stabilizer for albumin products2007
- Author(s)
  Anraku M, Kouno Y, Kai T, Tsurusaki Y, Yamasaki K, Otagiri M
- Journal Title
  
  Int J Pharm 329(1-2)
  
  Pages: 19-24
- NAID
  120005894408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Effects of endogenous ligands on the biological role of human serum albumin in S-nitrosylation2007
- Author(s)
  Ishima Y, Akaike T, Kragh-Hansen U, Hiroyama S, Sawa T, Maruyama T, Kai T, Otagiri M
- Journal Title
  
  Biochem Biophys Res Commun 364(4)
  
  Pages: 790-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Changes of net charge and α-helical content affect the pharmacokinetic properties of human serum albumin2007
- Author(s)
  Iwao Y, Hiraike M, Kragh-Hansen U, Mera K, Noguchi T, Anraku M, Kawai K, Maruyama T, Otagiri M
- Journal Title
  
  Biochimica et Biophysica Acta-Proteins and Proteomics 1774(12)
  
  Pages: 1582-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Recombinant human serum albumin2007
- Author(s)
  Chuang VTG, Otagiri M
- Journal Title
  
  Drugs of Today 43(8)
  
  Pages: 547-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] S-nitrosylation of human variant albumin liprizzi(R410C)confers potent antibacterial and cytoprotective properties2007
- Author(s)
  Ishima Y, Sawa T, Kragh-Hansen U, Miyamoto Y, Matsushita S, Akaike T, Otagiri M
- Journal Title
  
  J Pharmacol Exp Ther 320(3)
  
  Pages: 969-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Stereoselective binding of human serum albumin2006
- Author(s)
  Chuang VTG, Otagiri M
- Journal Title
  
  Chirality 18(3)
  
  Pages: 159-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Oxidation of arg-410 promotes the elimination of human serum albumin2006
- Author(s)
  Iwao Y, Anraku M, Yamasaki K, Kragh-Hansen U, Kawai K, Maruyama T, Otagiri M
- Journal Title
  
  Biochimica et Biophysica Acta - Proteins and Proteomics 1764(4)
  
  Pages: 743-9
- NAID
  120005499993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products(AOPP)2006
- Author(s)
  Iwao Y, Anraku M, Hiraike M, Kawai K, Nakajou K, Kai T, Suenaga A, Otagiri M
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 21(2)
  
  Pages: 140-6
- NAID
  120005499992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis2006
- Author(s)
  Kragh-Hansen U, Watanabe H, Nakajou K, Iwao Y, Otagiri M
- Journal Title
  
  J Mol Biol 363(3)
  
  Pages: 702-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Recombinant human serum albumin dimer has high blood circulation activity and low vascular permeability in comparison with native human serum albumin2006
- Author(s)
  Matsushita S, Chuang VTG, Kanazawa M, Tanase S, Kawai K, Maruyama T, Suenaga A, Otagiri M
- Journal Title
  
  Pharm Res 23(5)
  
  Pages: 882-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390051
[Journal Article] Renal clearance of glycolaldehyde- and methylglyoxal-modified proteins in mice is mediated by mesangial cells through a class A scavenger receptor (SR-A).2005
- Author(s)
  Nakajou K, Horiuchi S, Sakai M, Haraguchi N, Tanaka M, Takeya M, Otagiri M.
- Journal Title
  
  Diabetologia 48
  
  Pages: 317-327
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Physicochemical characterization of cross-linked human serum albumin dimer and its synthetic heme hybrid as an oxygen carrier.2004
- Author(s)
  Komatsu T, Oguro Y, Teramura Y, Takeoka S, Okai J, Anraku M, Otagiri M, Tsuchida E.
- Journal Title
  
  Biochimica et Biophysica Acta 1675
  
  Pages: 21-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress.2004
- Author(s)
  Anraku M, Tsurusaki Y, Watanabe H, Maruyama T, Kragh-Hansen U, Otagiri M.
- Journal Title
  
  Biochimica et Biophysica Acta 1702
  
  Pages: 9-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Effect of genetic variation on the thermal stability of human serum albumin.2004
- Author(s)
  Kragh-Hansen U, Saito S, Nishi K, Anraku M, Otagiri M.
- Journal Title
  
  Biochimica et Biophysica Acta 1747
  
  Pages: 81-88
- NAID
  120005499985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients.2004
- Author(s)
  Anraku M, Kitamura K, Shinohara A, Adachi M, Suenaga A, Maruyama T, Miyanaka K, Miyoshi T, Shiraishi N, Nonoguchi H, Otagiri M, Tomita K.
- Journal Title
  
  Kidney International 66
  
  Pages: 841-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Functional analysis of recombinant human serum albumin domains for pharmaceutical applications.2004
- Author(s)
  Matsushita S, Isima Y, Chuang VTG, Watanabe H, Tanase S, Maruyama T, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 21
  
  Pages: 1924-1932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Validation of the chloramine-T induced oxidation of human serum albumin as a model for oxidative damage in vivo.2003
- Author(s)
  Anraku M, Kragh-Hansen U, Kawai K, Maruyama T, Yamasaki Y, Takakura Y, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 20
  
  Pages: 684-692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] The effect of glycation on the structure, function and biological fate of human serum albumin as revealed by recombinant mutants.2003
- Author(s)
  Nakajou K, Watanabe H, Kragh-Hansen U, Maruyama T, Otagiri M.
- Journal Title
  
  Biochimica et Biophysica Acta 1623
  
  Pages: 88-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Practical aspects of the ligand-binding and enzymatic properties of human serum albumin. Review2002
- Author(s)
  Kragh-Hansen U, Chuang VTG, Otagiri M.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 25
  
  Pages: 695-704
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] In vivo kinetic analysis of covalent binding between N-acetyl-L-cysteine and plasma protein through the formation of mixed disulfide in rats.2002
- Author(s)
  Harada D, Naito S, Hiraoka I, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 19
  
  Pages: 615-620
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] How do fatty acids cause allosteric binding of drugs to human serum albumin?2002
- Author(s)
  Chuang VTG, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 19
  
  Pages: 1458-1464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Pharmaceutical strategies utilizing recombinant human serum albumin. Review2002
- Author(s)
  Chuang VTG, Kragh-Hansen U, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 19
  
  Pages: 569-577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] N-acetyl-L-cysteine and albumin through the formation of mixed disulfides in human and rat serum in vitro.2002
- Author(s)
  Harada D, Naito S, Otagiri M.
- Journal Title
  
  Pharmaceutical Research 19
  
  Pages: 1648-1654
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370759
[Journal Article] Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells.
- Author(s)
  Taguchi K,, Maruyama T,, Otagiri M.
- Journal Title
  
  Drug Metab Rev.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390161
[Journal Article] Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells.
- Author(s)
  Taguchi K, Maruyama T, Otagiri M.
- Journal Title
  
  Drug Metab Rev.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659042
[Patent] α１－酸性糖タンパク質の血中濃度上昇をメカニズムとした慢性腎臓病治療薬2017
- Inventor(s)
  丸山徹、渡邊博志、異島優、藤村留依、小田切優樹
- Industrial Property Rights Holder
  丸山徹、渡邊博志、異島優、藤村留依、小田切優樹
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K15320
[Patent] α１－酸性糖タンパク質の血中濃度上昇をメカニズムとした慢性腎臓病治療薬2017
- Inventor(s)
  丸山徹、渡邊博志、異島優、藤村留依、小田切優樹
- Industrial Property Rights Holder
  丸山徹、渡邊博志、異島優、藤村留依、小田切優樹
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16H05114
[Patent] α１－酸性糖タンパク質の血中濃度の上昇をメカニズムとした慢性腎臓病治療薬2017
- Inventor(s)
  丸山徹、渡邊博志、異島優、藤村留衣、小田切優樹
- Industrial Property Rights Holder
  丸山徹、渡邊博志、異島優、藤村留衣、小田切優樹
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K15320
[Patent] 抗癌剤増感剤2011
- Inventor(s)
  小田切優樹、異島優、渡邊博志、丸山徹
- Industrial Property Rights Holder
  ニプロ株式会社
- Filing Date
  2011-08-12
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] S-ニトロソ化α1-酸性糖タンパク質を含有する抗菌剤2011
- Inventor(s)
  渡辺佳織、異島優、末永綾香、渡邊博志、甲斐俊哉、丸山徹、小田切優樹
- Industrial Property Rights Holder
  ニプロ株式会社
- Filing Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] 高リガンド親和性アルブミン変異体の製造方法2010
- Inventor(s)
  蓑毛藍、異島優、丸山徹、森岡弘志、小田切優樹
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2010-172277
- Acquisition Date
  2010-08-12
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] S-ニトロソ基含有アルブミン及びその製造方法ならびに抗がん剤2009
- Inventor(s)
  小田切優樹、中城圭介、片山直久、甲斐俊哉
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2009-057318
- Acquisition Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] S-ニトロソ基含有アルブミン及びその製造方法ならびに抗がん剤2009
- Inventor(s)
  小田切優樹, ら
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2009-057318
- Acquisition Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-18390051
[Patent] 融合タンパク質、該融合タンパク質に関連する遺伝子、ベクター、形質転換体及び抗炎症性医薬組成物2009
- Inventor(s)
  小田切優樹、生田祥太朗
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2009-055838
- Acquisition Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] 融合タンパク質、該融合タンパク質に関連する遺伝子、ベクター、形質転換体及び抗炎症性医薬組成物2009
- Inventor(s)
  小田切優樹, ら
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2009-055838
- Acquisition Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-18390051
[Patent] 糖鎖含有アルブミン、その製造方法およびその用途2008
- Inventor(s)
  中城圭介、片山直久、甲斐俊哉、小田切優樹
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2008-043285
- Acquisition Date
  2008-02-28
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] 脂肪酸を含有するS-ニトロソタンパク質とその製法2008
- Inventor(s)
  異島優、赤池孝章、小田切優樹
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2008-050294
- Acquisition Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] ピキア酵母を用いた組換えヒトヘモグロビンの製造2008
- Inventor(s)
  中城圭介、帆足洋平、甲斐俊哉、宇野公之、小田切優樹
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2008-017774
- Acquisition Date
  2008-01-31
- Data Source
  KAKENHI-PROJECT-21390177
[Patent] 血清アルブミン多量体を含む遺伝子組換え型蛋白質2006
- Inventor(s)
  小田切優樹ら
- Industrial Property Rights Holder
  ニプロ株式会社
- Patent Publication Number
  2006-238788
- Acquisition Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-18390051
[Presentation] 一酸化窒素とチオールを基軸とした新規NASH治療法の開発2022
- Author(s)
  前田仁志、異島優、小田切優樹、渡邊博志、丸山徹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] The EPR effect and beyond: Drug delivery for refractory cancer therapy via an Endogenous Albumin Transport system2022
- Author(s)
  異島優、丸山徹、赤池孝章、小田切優樹、石田竜弘
- Organizer
  Redox Week in Sendai 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02645
[Presentation] 超硫黄分子のレドックス制御機構の解明と抗酸化剤への応用2022
- Author(s)
  池田真由美、異島優、丸山徹、小田切優樹、石田竜弘
- Organizer
  第30回DDSカンファランス
- Data Source
  KAKENHI-PROJECT-21H02645
[Presentation] 様々な生体液に含まれる超硫黄分子の生理的意義の解明2022
- Author(s)
  異島優、池田真由美、酒井真紀、長船裕輝、岩尾康範、丸山徹、小田切優樹、石田竜弘
- Organizer
  フォーラム2022:衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-21H02645
[Presentation] 酸性環境応答性を発揮するアルブミン結合型抗がん剤の作製と抗腫瘍効果2022
- Author(s)
  月川健士、井本修平、今村思音、入江直樹、西　弘二、堤　敏彦、横山祥子、小田切優樹、山崎啓之
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] がん間質細胞を二重標的化する抗がん剤送達キャリアの開発と新規がんDDS戦略の構築2021
- Author(s)
  水田夕稀、前田仁志、皆吉勇紀、一水翔太、木下遼、異島優、渡邊博志、小田切優樹、丸山徹
- Organizer
  第37回日本DDS学会学術集
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2021
- Author(s)
  西弘二、別府拓豪、井本修平、異島優、月川健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] がん間質細胞を標的とするDDS担体の開発2021
- Author(s)
  前田仁志、水田夕稀、異島優、渡邊博志、小田切優樹、丸山徹
- Organizer
  第28回日本血液代替物学会年次大会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 酸性環境応答性を有するアルブミン結合型抗がん剤の作製と評価2021
- Author(s)
  月川健士、井本修平、西弘二、堤敏彦、横山祥子、小田切優樹、山﨑啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] アルブミン内包リポソームの設計と評価：アルブミン内封量に及ぼす脂質電荷の影響2021
- Author(s)
  長谷川喬史、西弘二、岡本侑子、田口和明、月川健士、小田切優樹、山﨑啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] アルブミン内包リポソームの設計と評価：アルブミン内封量に及ぼす脂質電荷の影響2021
- Author(s)
  長谷川喬史、西弘二、岡本侑子、田口和明、月川健士、小田切優樹、山﨑啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] B型肝炎ウイルス新規治療候補薬の健常ラット及び腎障害モデルラットにおける体内動態解析2020
- Author(s)
  橋本麻衣、田口和明、山﨑啓之、井本修平、満屋裕明、小田切優樹
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 潰瘍性大腸炎モデルマウスにおけるラクトフェリンナノ粒子の治療効果2020
- Author(s)
  田口和明、橋本麻衣、中山真雪、榎木裕紀、西弘二、松元一明、瀬尾量、小田切優樹、山﨑啓之
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 潰瘍性大腸炎モデルマウスにおけるラクトフェリンナノ粒子の治療効果2020
- Author(s)
  渡部佑樹、田口和明、榎木裕紀、酒井宏水、丸山徹、小田切優樹、河野光智、松元一明
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 一酸化炭素結合型ヘモグロビン小胞体の閉塞性細気管支炎に対する有効性評価2020
- Author(s)
  渡部佑樹、田口和明、榎木裕紀、酒井宏水、丸山徹、小田切優樹、河野　光智、松元　一明
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 存赤血球輸血が肝cytochromeP450に与える影響2020
- Author(s)
  田口和明、得能正裕、山崎啓之、小田切優樹
- Organizer
  第27回日本血液代替物学会年次大会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] ヘモグロビンを担体とした一酸化炭素デリバリーシステムによる腎疾患治療戦略2020
- Author(s)
  永﨑　太清、前田　仁志、田口　和明、柳澤　洋輝、西田　健人、酒井　宏水、深川　雅史、渡邊　博志、小田切　優樹、丸山　　徹
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 一酸化炭素付加機能性赤血球は包括的に急性腎障害の病態を改善する2020
- Author(s)
  永崎太清、田口和明、柳澤洋輝、西田健人、前田仁志、酒井宏水、渡邊博志、深川雅史、小田切優樹、丸山徹
- Organizer
  第27回日本血液代替物学会年次大会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] Albumin fusion protein: next generation of albumin preparation2019
- Author(s)
  Toru Maruyama, Masaki Otagiri
- Organizer
  The 17th International Symposium on Blood Substitutes and Oxygen Therapeutics (XVII-ISBS-2019)
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 血清アルブミンの酸化ストレス応答を模倣した新規抗酸化剤の設計2019
- Author(s)
  池田真由美、異島優、清水太郎、安藤英紀、奥平桂一郎、渡邊博志、丸山徹、小田切優樹、石田竜弘
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] ヒト血清アルブミンに存在するポリスルフィドによるユニークな酸化ストレス応答2019
- Author(s)
  池田真由美、異島優、酒井真紀、清水太郎、安藤英紀、渡邊博志、丸山徹、小田切優樹、石田竜弘
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Pharmaceutical properties and potential application of recombinant human albumin dimer as a nanomedicine carrier2019
- Author(s)
  Masaki Otagiri
- Organizer
  AFPS-ICAPPS conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] Human albumin based drug delivery: SNO-albumin dimer for cancer therapeutic application.2019
- Author(s)
  Otagiri, M., Ishima, Y., Taguchi, K., Maruyama, T.
- Organizer
  17th International Symposium on Blood Substitutes & Oxygen Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] EPR増強剤の併用は膵臓癌に対するnab-パクリタキセルの治療効果を増強する2019
- Author(s)
  丸山徹、木下遼、前田仁志、渡邊博志、小田切優樹、異島優
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 慢性肝障害治療に対する肝クッパー細胞指向性1型インターフェロンの有用性評価2019
- Author(s)
  皆吉勇紀、前田仁志、渡邊博志、異島優、小田切優樹、丸山徹
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Development of a novel tumor microenvironment-targeted drug deliver carrier2019
- Author(s)
  水田夕稀、前田仁志、皆吉勇紀、一水翔太、木下遼、異島優、渡邊博志、小田切優樹、馬場秀夫、丸山徹
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 難治性膵臓がんにおけるアルブミンナノ粒子のサイズ最適化の検討2019
- Author(s)
  異島優、木下遼、平川尚樹、石田竜弘、小田切優樹、丸山徹
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 細胞膜透過型アルブミンの細胞内移行機序の解明～マクロピノサイトーシス誘導とエンドソーム脱出経路～2019
- Author(s)
  一水翔太、渡邊博志、前田仁志、清水太郎、異島優、石田竜弘、二木史朗、小田切優樹、丸山徹
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 抗体医薬を用いたがん治療に対するEPR増強剤SNO-HSA-dimerの効果2019
- Author(s)
  異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Human Albumin Based Drug Delivery: SNO-Albumin dimer for cancer therapeutic application2019
- Author(s)
  Masaki Otagiri
- Organizer
  The 17th International Symposium on Blood Substitutes and Oxygen Therapeutics (XVII-ISBS-2019)
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 脱溶媒和法により調製したドキソルビシン封入ヒト血清アルブミンナノ粒子の抗腫瘍効果に関する検討2019
- Author(s)
  山崎啓之、木村虎太郎、西弘二、猪原彩希、大島千佳、井本修平、田口和明、小田切優樹
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] Functional Elucidation of Polysulfides In Serum Albumin and Development of Biomimetic Donor of Polysulfides.2019
- Author(s)
  Ikeda, M., Ishima, Y., Watanabe, H., Maruyama, T., Otagiri, M., Ishida, T.
- Organizer
  2019 CRS Annual Meeting & Exposition.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 腫瘍関連マクロファージを標的とした新規DDS担体の開発2018
- Author(s)
  水田夕稀、前田仁志、異島優、皆吉勇紀、一水翔太、木下遼、渡邊博志、小田切優樹、丸山徹
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] Pharmaceutical Application of Recombinant Human Serum Albumin Dimer2018
- Author(s)
  Masaki Otagiri, Kazuaki Taguchi, Keishi Yamasaki, Yu Ishima, Toru Maruyama
- Organizer
  SICHEM2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 多剤耐性菌および真菌に対するS‐ニトロソ化Alpha1―酸性糖蛋白質の効果2018
- Author(s)
  異島優、石田竜弘, 金城雄樹、丸山徹、小田切優樹
- Organizer
  医療薬学フォーラム 2018
- Invited
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 新規抗菌剤SNO-AGPの多剤耐性菌に対する克服効果2018
- Author(s)
  異島優、渡辺佳織、小田切優樹、石田竜弘、丸山徹
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 新規腫瘍DDSキャリアである共有結合型アルブミンナノ粒子の有用性評価2018
- Author(s)
  木下遼、異島優、渡邊博志、清水太郎、石田竜弘、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] ポリスルフィド付加血清アルブミンによるメラニン産生の抑制2018
- Author(s)
  池田真由美、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 一酸化窒素を利用した血管透過性制御とがん治療応用2018
- Author(s)
  異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] アルブミン製剤中のサルフェン硫黄含有量の差異と抗酸化能の評価2018
- Author(s)
  酒井真紀、池田真由美、今福匡司、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] In silico解析へ向けたα1-酸性糖タンパク質異型間の薬物結合選択性に寄与するアミノ酸残基の同定2018
- Author(s)
  中村侑加、渡邊博志、中村照也、池鯉鮒麻美、石躍華奈、前田仁志、山縣ゆり子、小田切優樹、丸山徹
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 生体液中の活性イオウ分子種の検出と機能解明2018
- Author(s)
  池田真由美、異島優、渡邊博志、赤池孝章、丸山徹、小田切優樹、石田竜弘
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Study of structtual-chemistry of sodium 4-phenylbutyrate on its binding to serum albumin.2018
- Author(s)
  Masaki Otagiri, Keishi Yamasaki
- Organizer
  Annual European Pharma Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810
[Presentation] 副甲状腺ホルモンはcAMP/PI3K/PKC/PKA/NF-κBシグナル経路を介してシトクロームP450 3Aの発現低下に寄与する2017
- Author(s)
  池上孝明、渡邊博志、杉本龍星、平田憲史郎、陣上祥子、田中元子、深川雅史、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 副甲状腺ホルモンによるABCG2の発現抑制を介した尿酸蓄積機構2017
- Author(s)
  渡邊博志、杉本龍星、池上孝明、田中元子、深川雅史、小田切優樹、丸山徹
- Organizer
  日本薬剤学会　第32回年会
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] キトサンナノファイバーゲルの滞留性を利用した潰瘍性大腸炎モデルマウスへの応用2017
- Author(s)
  安楽誠、田渕良、庵原大輔、伊福伸介、小田切優樹、平山文俊
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県、仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] Therapeutic application of bone marrow-targeted liposome ～Encapsulation of erythropoietin for renal anemia treatment～2017
- Author(s)
  Kazuaki Taguchi, Toru Maruyama, Keitaro Sou, Masaki Otagiri
- Organizer
  International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)
- Place of Presentation
  Kyoto Reserch Park（京都府・京都市)
- Year and Date
  2017-03-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] 副甲状腺ホルモンはcAMP/PI3K/PKC/PKA/NF-κBシグナル経路を介してシトクロームP450 3Aの発現低下に寄与する2017
- Author(s)
  池上孝明、渡邊博志、杉本龍星、平田憲史郎、陣上祥子、田中元子、深川雅史、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] キトサンナノファイバー/シクロデキストリンゲルシートの調製と物性評価2017
- Author(s)
  田渕良、安楽誠、伊福伸介、庵原大輔、小田切優樹、平山文俊
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県、仙台市)
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 腎線維化マウスに対するビタミンD受容体活性化剤とビタミンA誘導体の治療効果（口頭発表）2016
- Author(s)
  Bi Jing、西田健人、藤村留衣、今福匡司、富永結菜、渡邊博志、小田切優樹、丸山徹
- Organizer
  第31回日本薬物動態学会
- Place of Presentation
  長野：キッセイ文化ホール　松本市総合体育館
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] CKD誘発骨格筋紹介に対するAST-120の有効性評価（口頭発表）2016
- Author(s)
  荒毛　里歩、榎木　裕紀、渡邊　博志、異島　優、田中　元子、松下　和孝、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川 : パシフィコ横浜、会議センター
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] 新規酸化ストレス早期発見に向けた血清パースルフィド定量の有用性評価（口頭発表）2016
- Author(s)
  池田真由美、異島優、渡邊博志、石田竜弘、小田切優樹、丸山徹
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科・薬学部
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] 新規酸化ストレス早期発見に向けた血清パースルフィド定量の有用性評価2016
- Author(s)
  池田真由美、異島優、渡邊博志、石田竜弘、小田切優樹、丸山徹
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科・薬学部（愛知県・名古屋市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] シクロデキストリン／キトサンナノファイバーゲルの創傷治癒促進効果2016
- Author(s)
  安楽誠、田渕良、東和生、伊福伸介、庵原大輔、上釜兼人、小田切優樹、平山文俊
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] バイオミメティックな一酸化炭素デリバリーによる炎症性腸疾患の治療効果2016
- Author(s)
  永尾　紗理、田口　和明、酒井　宏水、小田切　優樹、丸山　徹
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ　静岡コンベションアーツセンター（静岡県・静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] 慢性腎臓病における腎-多臓器連関に関わる尿毒素の関与とその分子機構2016
- Author(s)
  渡邊博志、異島優、小田切優樹、丸山徹
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] Design and evaluation of long-acting thioredoxin by using albumin fusion technology as a superior therapeutic agent for acute kidney injury (口頭発表、シンポジウム)2016
- Author(s)
  Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  第1回日韓若手薬剤学研究者ワークショップ(The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics )
- Place of Presentation
  京都：京都教育文化センター
- Year and Date
  2016-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] Renoprotective Effect of Long Acting Thioredoxin by Modulating Oxidative Stress and Macrophage Migration Inhibitory Factor Against Rhabdomyolysis associated Acute Kidney Injury（ポスター）2016
- Author(s)
  Kento Nishida, Hiroshi Watanabe, Tadashi Imafuku, Yu Ishima, Masaki Otagiri, Toru Maruyama
- Organizer
  第1回日韓若手薬剤学研究者ワークショップ(The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics )
- Place of Presentation
  京都：京都教育文化センター
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 慢性腎不全モデルラットにおけるキトサンナノファイバーの抗酸化及び腎保護効果2016
- Author(s)
  安楽誠、田渕良、庵原大輔、伊福伸介、小田切優樹、平山文俊
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場 (岐阜県、岐阜市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 慢性腎臓病における腎-多臓器連関に関わる尿毒素の関与とその分子機構2016
- Author(s)
  渡邊博志、異島優、小田切優樹、丸山徹
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] ヒト血清アルブミン－オクタン酸ナトリウム－N-アセチル-L-メチオニン三元複合体のX線結晶構造解析2016
- Author(s)
  小田切優樹、河合聡人、河野陽介、安楽誠、山崎啓之
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場および岐阜都ホテル（岐阜県・岐阜市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] クラッシュ症候群モデルラットに対する一酸化炭素付加赤血球の有用性評価2016
- Author(s)
  丸山徹、大柿滋、永崎太清、柳澤洋輝、永尾紗理、田口和明、渡邊博志、小田切優樹
- Organizer
  第23回日本血液代替物学会年次大会
- Place of Presentation
  早稲田大学西早稲田キャンパス（東京都・新宿区）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] 組換え型高マンノース付加アルブミンを担体とした肝クッパー細胞指向性インターフェロンα2bの設計と肝保護効果2016
- Author(s)
  皆吉　勇紀、前田　仁志、渡邊　博志、異島　優、小田切　優樹、丸山　徹
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ　静岡コンベションアーツセンター（静岡県・静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] Therapeutic Impact of Liver-Targeted Nitric Oxide Releasing Nano-Antioxidant on NASH2016
- Author(s)
  Hitoshi Maeda, Yu Ishima, Yuki Minayoshi, Shouta Ichimizu, Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics
- Place of Presentation
  京都教育文化センター（京都府・京都市）
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] 酸化ストレス早期発見に向けた血清パースルフィド定量の有用性評価（口頭発表）　*優秀発表賞2016
- Author(s)
  池田　真由美、異島　優、渡邉　博志、石田　竜弘、小田切　優樹、丸山　徹
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学群元キャンパス
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] AKI誘発急性肺障害モデルにおける血中滞留型チオレドキシンの有効性評価（口頭発表）2016
- Author(s)
  西田　健人、宮久　優子、渡邊　博志、異島　優、小田切　優樹、深川　雅史、丸山　徹
- Organizer
  第7回腎不全研究会
- Place of Presentation
  東京：全社協・灘尾ホール
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 腎線維化マウスに対するビタミンD受容体活性化剤とビタミンA誘導体の治療効果 (口頭発表) *優秀演題賞2016
- Author(s)
  Bi Jing、西田健人、藤村留衣、今福匡司、富永結菜、渡邊博志、小田切優樹、丸山徹
- Organizer
  第23回日本血液代替物学会年次大会
- Place of Presentation
  早稲田大学・西早稲田キャンパス55号館
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] Albumin as Nitric Oxide-Traffic Protein : Novel Anticancer Agent2016
- Author(s)
  Masaki Otagiri, Yu Ishima, Toru Maruyama
- Organizer
  International Conference On Nanomedicine And Nanobiotechnology 2016
- Place of Presentation
  Paris（France)
- Year and Date
  2016-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] Long-acting albumin-thioredoxin fusion protein ameliorates acute kidney injury and its associated acute lung injury*The APSTJ Global Education Seminar Presentation Award 20162016
- Author(s)
  Kento Nishida, Hiroshi Watanabe, Masako Miyahisa, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
- Organizer
  The APSTJ Global Education Seminar
- Place of Presentation
  長崎大学薬学部
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] NASH病態におけるDDS戦略の限界と一酸化窒素による治療抵抗性の克服2016
- Author(s)
  前田　仁志、異島　優、皆吉　勇紀、一水　翔太、柳澤　洋輝、渡邊　博志、小田切　優樹、丸山　徹
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科・薬学部（愛知県・名古屋市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] 腎糸球体への移行性を有するα 1-酸性糖蛋白質は糸球体バリア保持機能と抗炎症作用により慢性腎不全を改善する（ポスター発表）2016
- Author(s)
  藤村留衣、西田健人、渡邊博志、小田切　優樹、丸山徹
- Organizer
  第31回日本薬物動態学会
- Place of Presentation
  長野：キッセイ文化ホール　松本市総合体育館
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] α1―酸性糖タンパク質バリアント間の薬物結合選択性に寄与するアミノ酸残基の同定　（口頭発表）2016
- Author(s)
  石躍　華奈、渡邉　博志、中村　照也、池鯉鮒　麻美、小早川　敬博、石井　宏志、山縣　ゆり子、森岡　弘志、小田切　優樹、丸山　徹
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学群元キャンパス
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 急性相蛋白質であるα1-酸性糖蛋白質は抗炎症性作用によりアドリアマイシン腎症を改善する（口頭発表）2016
- Author(s)
  藤村　留衣、西田　健人、渡邊　博志、異島　優、小田切　優樹、丸山　徹
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜、会議センター
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K15320
[Presentation] 慢性腎臓病が誘発する骨格筋萎縮に対するAST-120の有効性評価2016
- Author(s)
  渡邊　博志、榎木　裕紀、荒毛　里歩、田中　元子、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第31回日本薬物動態学会
- Place of Presentation
  長野：キッセイ文化ホール　松本市総合体育館
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16H05114
[Presentation] 慢性腎臓病における定量的酸化ストレス評価法の確立とそれを基盤とした治療戦略2015
- Author(s)
  渡邊博志、田中元子、深川雅史、小田切優樹、丸山徹
- Organizer
  第32回和漢医薬学会学術大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2015-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] シクロデキストリン-キトサンナノファイバーゲルの徐放性素材への応用2015
- Author(s)
  田渕良、安楽誠、庵原大輔、伊福伸介、小田切優樹、平山文俊
- Organizer
  第32回日本薬学会九州支部学会大会
- Place of Presentation
  九州保健福祉大学（宮崎県、延岡市）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 副甲状腺ホルモンよるABCG2 の発現抑制は二次性副甲状腺機能亢進症における尿酸値の上昇に関与する2015
- Author(s)
  杉本龍星、渡邊博志、榎木裕紀、異島優、田中元子、松下和孝、駒場大峰、深川雅史、小田切優樹、丸山徹
- Organizer
  第6回腎不全研究会
- Place of Presentation
  東京：全社協・灘尾ホール
- Year and Date
  2015-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 副甲状腺ホルモンは ABCG2 の発現抑制を介して血清尿酸値を上昇させる2015
- Author(s)
  杉本龍星、渡邊博志、榎木裕紀、異島優、田中元子、松下和孝、駒場大峰、深川雅史、小田切優樹、丸山徹
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学薬学部
- Year and Date
  2015-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 人工赤血球製剤ヘモグロビン小胞体の体内動態2015
- Author(s)
  小田切優樹
- Organizer
  臨床応用化を目指した人工赤血球関連セミナー
- Place of Presentation
  旭川医科大学（北海道旭川市）
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] CLINICAL APPLICABITY OF THIOREDOXIN-ALBUMIN FUSION PROTEIN AGAINST OXIDATIVE STRESS RELATED DISEASES2015
- Author(s)
  Masaki Otagiri
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants
- Place of Presentation
  Institut Pasteur (Paris,France)
- Year and Date
  2015-06-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] シナカルセトは副甲状腺ホルモンが介在するABCG2発現抑制を解除することで尿酸排泄を促進する2015
- Author(s)
  杉本龍星、渡邊博志、榎木裕紀、異島優、田中元子、松下和孝、深川雅史、小田切優樹、丸山徹
- Organizer
  第30回日本薬物動態学会
- Place of Presentation
  東京：タワーホール船堀
- Year and Date
  2015-11-12
- Invited
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] DESIGN AND EVALUATION OF RECOMBINANT ALBUMIN DOMAIN WITH HIGH BILIRUBIN BINDING AFFINITY VIA PHAGE DISPLAY TECHNOLOGY2015
- Author(s)
  Masaki Otagiri
- Organizer
  International Bioanalytical Formulation Congress
- Place of Presentation
  Maritim proArte Hotel (Berlin,Germany)
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PROJECT-15K15008
[Presentation] シクロデキストリン-キトサンナノファイバーゲルの徐放性素材への応用2015
- Author(s)
  平賀歩，安楽誠，庵原大輔，伊福伸介，小田切優樹, 上釜兼人,平山文俊
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] Effects of chitosan on oxidative stress and related factors in chronic renal failure2015
- Author(s)
  Makoto Anraku, Daisuke Iohara, Motoko Tanaka, Toru Maruyama, Fumitoshi Hirayama, Masaki Otagiri
- Organizer
  12th International Conference of the European Chitin Society 13th International Conference on Chitin and Chitosan
- Place of Presentation
  Munster, Germany
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] Suppression of ABCG2 expression by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism2015
- Author(s)
  Ryusei Sugimoto, Hiroshi Watanabe, Yuki Enoki, Yu Ishima, Motoko Tanaka, Kazutaka Matsushita, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2015
- Place of Presentation
  Thailand , Rama Gardens Hotel
- Year and Date
  2015-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 市販のアルブミン製剤に対する機能と翻訳後修飾の関連性2015
- Author(s)
  今福匡司、宮村重幸、安楽誠、山崎啓之、富永結菜、異島優、渡邊博志、小田切優樹、丸山徹
- Organizer
  第30回日本薬物動態学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 新規尿毒症物質ニトロ化インドキシル硫酸の活性酸素誘導能2014
- Author(s)
  丸山　徹、成底　徹、渡邊　博志、小田切　優樹、深川　雅史、異島　優
- Organizer
  第5回腎不全研究会
- Place of Presentation
  東京：全社協・灘尾ホール
- Year and Date
  2014-12-13
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] ヒト血清アルブミンにおけるCys34-Cysteinylationの機序解明-肝硬変の影響-2014
- Author(s)
  南雲恒平（D3）、今福匡司、山田尚之、渡邊博志、異島優、田中基彦、佐々木裕、小田切優樹、丸山徹
- Organizer
  日本薬学会第134年会2014/3/27-30（熊本）
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 多剤耐性菌に対するS-ニトロソ化α1酸性糖タンパク質の抗菌作用渡邊佳織2014
- Author(s)
  異島優、黒田照夫、小川和加野、渡邊博志、甲斐俊哉、小田切優樹、丸山徹
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本 : くまもと森都心プラザ
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Pharmacokinetics of serum albumin variants.2014
- Author(s)
  M.Otagiri
- Organizer
  Innovation workshop on Albumin: The next generation protein therapeutics 2014
- Place of Presentation
  Chicago (USA)
- Year and Date
  2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] ESI-TOFMSを用いた透析患者由来ヒト血清アルブミンの翻訳後修飾解析2014
- Author(s)
  宮村重幸（D3社会人）、南雲恒平、杉森剛志、渡邊博志、山田尚之、小田切優樹、丸山徹
- Organizer
  日本薬学会第134年会2014/3/27-30（熊本）
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] エリスロポエチン骨髄デリバリーシステムの腎性貧血治療への応用2014
- Author(s)
  丸山徹、田口和明、宮崎裕理、渡邊博志、宗慶太郎、末永綾香、異島優、小田切優樹
- Organizer
  日本薬学会第134年会2014/3/27-30（熊本）
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 尿毒症物質パラクレジル硫酸によるNADPH oxidase活性化を介した尿細管及び血管障害作用2014
- Author(s)
  渡邊　博志、宮本　洋平、異島　優、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第26回腎とフリーラジカル研究会
- Place of Presentation
  産業労働センターウインクあいち
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] Pharmacokinetics of serum albumin variants.2014
- Author(s)
  M.Otagiri
- Organizer
  Innovation workshop on Albumin: The next generation protein therapeutics 2014
- Place of Presentation
  Chicago (USA)
- Year and Date
  2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-25670085
[Presentation] Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate2014
- Author(s)
  Hiroshi Watanabe, Yoshiaki Sakaguchi, Ryusei Sugimoto, Yu Ishima, Ken-ichi Kaneko, Hiroshi Iwata, Masaki Otagiri and Toru Maruyama
- Organizer
  8th International Society on Uremia Research and Toxicity
- Place of Presentation
  Okinawa convention hall
- Invited
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 尿毒症物質パラクレジル硫酸によるNADPH oxidase活性化を介した尿細管及び血管障害作用2014
- Author(s)
  渡邊　博志、宮本　洋平、異島　優、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第26回腎とフリーラジカル研究会
- Place of Presentation
  産業労働センターウインクあいち
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 高分子抗癌剤の腫瘍集積性を高めるS-ニトロソ化アルブミンダイマーのEPR効果増強作用2013
- Author(s)
  異島優、方軍、前田浩、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知、ウインクあいち
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] S-NITROSATEDα-1-ACID GLYCOPROTEIN KILLS DRUG-RESISTANT BACTERIA AND AIDS SURVIVAL IN SEPSIS2013
- Author(s)
  Kaori Watanabe, Yu Ishima, Teruo Kuroda, Wakano Ogawa, Hiroshi Watanabe, Ayaka Suenaga, Toshiya Kai, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  東京 : タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] 尿毒症物質p-クレジル硫酸の酸化ストレス誘導を介した尿細管障害作用2013
- Author(s)
  渡邊博志、宮本洋平、田中寿絵、異島優、田中元子、松下和孝、深川雅史、小田切優樹、丸山徹
- Organizer
  第58回日本透析医学会学術集会総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] A human serum albumin–thioredoxin fusion protein prevents experimental contrast-induced nephropathy2013
- Author(s)
  Hiroshi Watanabe, Azusa Kodama, Ryota Tanaka, Hisae Tanaka, Victor Tuan Giam Chuang, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel, Jeju, Korea
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] クッパー細胞選択的チオール送達によるアセトアミノフェン肝障害治療法の開発2013
- Author(s)
  前田仁志、平田憲史郎、渡邊博志、異島優、末永綾香、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知、ウインクあいち
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Albumin-Thioredoxin Fusion Protein is Effective in Suppressing Lung Injury.2013
- Author(s)
  Masaki Otagiri
- Organizer
  9th Retrometabolism Based Drug Design and Targeting Conferenece
- Place of Presentation
  アメリカ・オーランド
- Invited
- Data Source
  KAKENHI-PROJECT-25670085
[Presentation] S-NITROSATED α-1-ACID GLYCOPROTEIN KILLS DRUG-RESISTANT BACTERIA AND AIDS SURVIVAL IN SEPSIS2013
- Author(s)
  Kaori Watanabe（D3）, Yu Ishim, Teruo Kuroda, Wakano Ogawa, Hiroshi Watanabe, Ayaka Suenaga, Toshiya Kai, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression2013
- Author(s)
  Ryota Tanaka, Hiroshi Watanabe, Yu Ishima, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] Albumin-Thioredoxin Fusion Protein is Effective in Suppressing Lung Injury2013
- Author(s)
  Masaki Otagiri
- Organizer
  9th Retrometabolism Based Drug Design and Targeting Conferenece
- Place of Presentation
  アメリカ・オーランド
- Invited
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] 遺伝子組換え型糖鎖付加アルブミンによるクッパー細胞選択的チオール送達は急性肝障害を改善する2013
- Author(s)
  前田仁志（D2）、平田憲史郎、渡邊博志、異島優、末永綾香、小田切優樹、丸山徹
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 遺伝子組換え型糖鎖付加アルブミンによるクッパー細胞選択的チオール送達は急性肝障害を改善する2013
- Author(s)
  前田仁志, 平田憲史郎, 渡邊博志, 異島優, 末永綾香, 小田切優樹, 丸山徹
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学本郷キャンパス
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] 尿毒症物質インドキシル硫酸の生物活性に及ぼす活性酸化窒素種の影響2013
- Author(s)
  成底徹, 異島優, 小谷俊介, 中島誠, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄県医師会館
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] ブレオマイシン誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2013
- Author(s)
  小田切優樹
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Development of recombinant serum2013
- Author(s)
  Masaki Otagiri
- Organizer
  The International Liver Congress 2013 48th annual meeting of the European association for the study of the liver
- Place of Presentation
  オランダ・アムステルダム
- Invited
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] MECHANISM OF ENHANCED CYSTEINYLATION OF Cys34 IN HUMAN SERUM ALBUMIN IN CHRONIC LIVER DISEASE2013
- Author(s)
  Kohei Nagumo（D3）, Tsuyosi Sugimori, Naoyuki Yamada, Hiroshi Watanabe, Yu Ishima, Motohiko Tanaka, Yutaka Sasaki, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会　第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 高分子抗癌剤の腫瘍集積性を高めるS-ニトロソ化アルブミンダイマーのEPR効果増強作用2013
- Author(s)
  異島優, 方軍, 前田浩, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄県医師会館
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] 尿毒素の酸化ストレス誘導を介したマウス骨格筋細胞障害作用2013
- Author(s)
  榎木裕紀（D2）、渡邊博志、異島優、小田切優樹、丸山徹
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 尿毒症物質p-クレジル硫酸の腎排泄過程におけるhOATsの関与2013
- Author(s)
  坂口義明（B6）、渡邊博志、宮本洋平、異島優、金子健一、岩田宏、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] ESI-TOF MSを用いた透析患者由来ヒト血清アルブミンの翻訳後修飾解析2013
- Author(s)
  南雲恒平（D3）、杉森剛志、阿部貴弥、申曽洙、渡邊博志、山田尚之、田中元子、松下和孝、小田切優樹、丸山徹
- Organizer
  第58回日本透析医学会学術集会総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] S-nitrosated α-1-acid glycoprotein kills drug-resistant bacteria and aids survival in sepsis2013
- Author(s)
  Kaori Watanabe (D3), Yu Ishima, Teruo Kuroda, Wakano Ogawa, Hiroshi Watanabe, Ayaka Suenaga, Toshiya Kai, Masaki Otagiri, and Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel（韓国）
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] Poly-S-nitrosated Human Serum Albumin inhibits the Expression of P-glycoprotein Transporter in Human Multidrug-resistant Tumor2013
- Author(s)
  Yu Ishima, Marie Hara, Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Development of recombinant serum albumin.2013
- Author(s)
  Masaki Otagiri
- Organizer
  The International Liver Congress 2013 48th annual meeting of the European association for the study of the liver
- Place of Presentation
  オランダ・アムステルダム
- Invited
- Data Source
  KAKENHI-PROJECT-25670085
[Presentation] Therapeutic impact of human serum albumin-thioredoxin fusion protein, long-acting anti-oxidative and anti-inflammatory modulator, against acetaminophen-induced acute liver failure2013
- Author(s)
  Ryota Tanaka, Hitoshi Maeda, Azusa Kodama, Hiroshi Watanabe, Yu Ishima, Toru Maruyama and Masaki Otagiri
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] A human serum albumin-thioredoxin fusion protein prevents experimental contrast-induced nephropathy2013
- Author(s)
  Azusa Kodama, Hiroshi Watanabe, Ryota Tanaka, Hisae Tanaka, Victor Tuan Giam Chuang, Yohei Miyamoto, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] ヒト有機アニオントランスポーターは尿毒症物質p-クレジル硫酸の高容量性トランスポーターとして機能する（2013
- Author(s)
  杉本龍星（D1）、渡邊博志、坂口義明、宮本洋平、異島優、金子健一、岩田宏、小田切優樹、丸山徹
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 高分子抗癌剤の腫瘍集積性を高めるS-ニトロソ化アルブミンダイマーのEPR効果増強作用2013
- Author(s)
  異島優、方軍、前田浩、渡邊博志、小田切優樹、丸山徹
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄県医師会館
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression2013
- Author(s)
  Ryota Tanaka, Hiroshi Watanabe, Yu Ishima, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Mechanism of enhanced cysteinylation of Cys34 in human serum albumin in chronic liver disease2013
- Author(s)
  Kohei Nagumo (D3), Tadashi Imafuku, Naoyuki Yamada, Hiroshi Watanabe, Yu Ishima, Motohiko Tanaka, Yutaka Sasaki, Masaki Otagiri and Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] TRANSPORT OF P-CRESYL SULFATE, A UREMIC TOXIN, VIA HUMAN ORGANIC ANION TRANSPORTER2013
- Author(s)
  Hiroshi Watanabe, Yoshiaki Sakaguchi, Ryusei Sugimoto, Yu Ishima, Ken-ichi Kaneko, Hiroshi Iwata, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会　第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] ブレオマイシン誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2013
- Author(s)
  小田切優樹
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 一酸化窒素付加型アルブミンによる抗癌剤耐性克服効果とその機序解明2013
- Author(s)
  異島優、原茉梨絵、甲斐俊哉、渡邊博志、末永綾香、小田切優樹、丸山徹
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 尿毒症物質インドキシル硫酸の生物活性に及ぼす活性酸化窒素種の影響成底徹2013
- Author(s)
  異島優、小谷俊介、中島誠、渡邊博志、小田切優樹、丸山徹
- Organizer
  第13回日本NO学会学術集会
- Place of Presentation
  沖縄県医師会館
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Kupffer cell selective delivery of thiols by genetically engineered mannosylated-albumin as a new therapeutic strategy for hepatitis2013
- Author(s)
  Hitoshi Maeda, Hiroshi Watanabe, Yu Ishima, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] アルブミン-チオレドキシン融合蛋白質はヨード造影剤腎症の発症を予防する2013
- Author(s)
  渡邊博志, 小玉あずさ, 田中遼大, 田中寿絵, 異島優, 深川雅史, 小田切優樹, 丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知, ウインクあいち
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] クッパー細胞選択的チオール送達によるアセトアミノフェン肝障害治療法の開発2013
- Author(s)
  前田仁志（D2）、平田憲史郎、渡邊博志、異島優、末永綾香、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] A human serum albumin-thioredoxin fusion protein prevents experimental contrast-induced nephropathy2013
- Author(s)
  Hiroshi Watanabe, Azusa Kodama, Ryota Tanaka, Hisae Tanaka, Victor Tuan Giam Chuang, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] アルブミン-チオレドキシン融合体によるシスプラチン腎症予防効果2013
- Author(s)
  小玉あずさ, 田中遼大, 渡邊博志, 異島優, 深川雅史, 小田切優樹, 丸徹日
- Organizer
  本薬剤学会第28年会
- Place of Presentation
  愛知, ウインクあいち
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] アルブミンーチオレドキシン誘導体による薬剤性急性腎障害の発症予防と機序解明2013
- Author(s)
  小玉あずさ, 渡邊博志, 田中遼大, 田中寿絵, 異島優, 深川雅史, 小田切優樹, 丸山徹
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学本郷キャンパス
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment.2013
- Author(s)
  Toru Maruyama, Yu Ishima, Ai Minomo, Toru Narisoko, Hiroshi Morioka, Hiroshi Watanabe, Masaki Otagiri
- Organizer
  The 5th Asian Arden Conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-24390028
[Presentation] 高分子抗癌剤の腫瘍集積性を高めるS-ニトロソ化アルブミンダイマーのEPR効果増強作用2013
- Author(s)
  異島優, 方軍, 前田浩, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知, ウインクあいち
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] Poly-S-nitrosated Human Serum Albumin inhibits the Expression of P-glycoprotein Transporter in Human Multidrug-resistant Tumor2013
- Author(s)
  Yu Ishima, Marie Hara, Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  The 5th Asian Arden conference
- Place of Presentation
  Aichi Gakuin University
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] ブレオマイシン誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2013
- Author(s)
  小田切優樹
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] 骨髄標的化エリスロポエチンの製剤設計と腎性貧血治療への応用2013
- Author(s)
  丸山徹, 宮崎裕理, 田口和明, 渡邊博志, 宗慶太郎, 田中元子, 松下和孝, 深川雅史, 小田切優樹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知, ウインクあいち
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] クッパー細胞選択的チオール送達によるアセトアミノフェン肝障害治療法の開発2013
- Author(s)
  前田仁志, 平田憲史郎 , 渡邊博志, 異島優, 末永綾香, 小田切優樹, 丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知, ウインクあいち
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] アルブミン-チオレドキシン融合体によるシスプラチン腎症予防効果2013
- Author(s)
  小玉あずさ、田中遼大、渡邊博志、異島優、深川雅史、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知、ウインクあいち
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] S-nitrosated a-1-acid glycoprotein kills drug-resistant bacteria and aids survival in sepsis2013
- Author(s)
  Kaori Watanabe, Yu Ishima, Teruo Kuroda, Wakano Ogawa, Hiroshi Watanabe, Ayaka Suenaga, Toshiya Kai, Masaki Otagiri, and Toru Maruyama
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Ramada Plaza Jeju Hotel, Jeju, Korea
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Alpha1-酸性糖タンパク質バリアント間のリガンド結合選択性機序解明2013
- Author(s)
  石井宏志、中村照也、小野知実、和泉実代子、渡邊博志、小田切優樹、山縣ゆり子、丸山徹
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎国際大学
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] S-ニトロソ化アルブミンダイマーはEPR 効果を増強する2012
- Author(s)
  井上亜希, 異島優, 方軍, 前田浩, 小田切優樹, 渡邊博志, 丸山徹
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] Human serum albumin as a nanomedecine carrir.2012
- Author(s)
  OtagiriM
- Organizer
  Nanoformulation 2012.
- Place of Presentation
  Fira Palace, Barcelona(招待講演)
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] ヒト血清アルブミンドメインIIによるビリルビン尿中排泄促進作用2012
- Author(s)
  小田切　優樹
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] The potential of albumin for use as a nanomedicine carrier.2012
- Author(s)
  Otagiri M.
- Organizer
  Montreal 2012 international forum on enviroment and medicine
- Place of Presentation
  Montreal, Quebec, Canada(招待講演)
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] Human serum albumin as a nanomedecine carrir2012
- Author(s)
  Otagiri M
- Organizer
  Nanoformulation 2012
- Place of Presentation
  Fira Palace, Barcelona (Spain)
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Human serum albumin as a nanomedecine carrir.2012
- Author(s)
  Otagiri M
- Organizer
  Nanoformulation 2012.
- Place of Presentation
  Fira Palace, Barcelona
- Invited
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] S-ニトロソ化アルブミンにより抗アポトーシス効果を付与した改良型臓器保存液の開発2012
- Author(s)
  異島優, 品川拓也, 米重梓二, 甲斐俊哉, 赤池孝章, 小田切優樹, 丸山徹
- Organizer
  第12回日本NO 学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] S-ニトロソ化に伴うα1-酸性糖タンパク質(AGP)の抗菌機能獲得と感染症治療への応用2012
- Author(s)
  渡辺佳織、異島優、赤池孝章、澤智裕、黒田照夫、小川和加野、渡邊博志、甲斐俊哉、小田切優樹、丸山徹
- Organizer
  第12回日本NO学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] ヒト血清アルブミンドメインIIによるビリルビン尿中排泄促進作用2012
- Author(s)
  小田切優樹
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] The potential of albumin for use as a nanomedicine carrier.2012
- Author(s)
  Otagiri M.
- Organizer
  Montreal 2012 international forum on enviroment and medicine.
- Place of Presentation
  Montreal,Quebec,Canada
- Invited
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] ヒト血清アルブミンドメインIIによるビリルビン尿中排泄促進作用2012
- Author(s)
  小田切優樹
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] ヒト血清アルブミンドメインIIによるビリルビン尿中排泄促進作用2012
- Author(s)
  小田切優樹
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] ヒト血清アルブミンドメインIIによるビリルビン尿中排泄促進作用2012
- Author(s)
  小田切　優樹
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] The potential of albumin for use as a nanomedicine carrier2012
- Author(s)
  Otagiri M
- Organizer
  Montr eal2012 international forum on enviroment and medicine.
- Place of Presentation
  Montreal,Quebec Canada
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Poly-SNO-アルブミンによる抗癌剤耐性克服効果と機序解明2012
- Author(s)
  異島優, 原茉梨絵, 末永綾香, 甲斐俊哉, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] S-ニトロソ化に伴うα1-酸性糖タンパク質(AGP)の抗菌機能獲得と感染症治療への応用2012
- Author(s)
  渡辺佳織、異島優、赤池孝章、澤智裕、黒田照夫、小川和加野、渡邊博志、甲斐俊哉、小田切優樹、丸山徹
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都大学薬学部
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] S-ニトロソ化アルブミンダイマーはEPR効果を増強する2012
- Author(s)
  井上亜希、異島優、方軍、前田浩、小田切優樹、渡邊博志、丸山徹
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] S-ニトロソ化に伴うα1-酸性糖タンパク質の抗菌機能獲得と感染症治療への応用2012
- Author(s)
  渡辺佳織、異島優、黒田照夫、小川和加野、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本動物実験代替法学会第25回
- Place of Presentation
  慶應義塾大学薬学部芝共立キャンパス
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] SPRによる自己組織化膜(SAMs)上に固定化されたビリルビンとヒト血清アルブミンドメインの結合評価2012
- Author(s)
  笠毛映理子,蓑毛藍,堀内智裕,諏訪喜昭,渡辺栄治,異島優,丸山徹,小田切優樹,森岡弘志
- Organizer
  BMAS2012 第25回バイオメディカル分析科学シンポジウム
- Place of Presentation
  慶応義塾大学薬学部芝共立キャンパス
- Year and Date
  2012-08-09
- Data Source
  KAKENHI-PROJECT-24390028
[Presentation] S-ニトロソ化アルブミンにより抗アポトーシス効果を付与した改良型臓器保存液の開発2012
- Author(s)
  異島優、品川拓也、米重梓二、甲斐俊哉、赤池孝章、小田切優樹、丸山徹
- Organizer
  第12回日本NO学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24659076
[Presentation] Carbon monoxide bound red blood cells prevent alteration of hepatic cytochrome P450 activity after hemorrhagic shock and resuscitation2011
- Author(s)
  Shigeru Ogaki, Masaki Otagiri, et al
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 尿毒症物質p-cresyl sulfateの酸化ストレスに及ぼす影響2011
- Author(s)
  本田大輔、宮本洋平、渡邊博志、門脇大介、丸山徹、小田切優樹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Carbon monoxide bound red blood cells prevent alteration of hepatic cytochrome P450 activity after hemorrhagic shock and resuscitation2011
- Author(s)
  Ogaki S, Otagiri M, et al.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions2011
- Author(s)
  Yohei Miyamoto, Masaki Otagiri, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Mono-SNO-HSA とPoly-SNO-HSA による細胞内NO 輸送機構の解明2011
- Author(s)
  異島優, 原茉梨絵, 末永綾香, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第11回日本NO 学会学術集会
- Place of Presentation
  昭和薬科大学
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] Poly-SNO-アルブミンによる抗癌剤耐性克服効果2011
- Author(s)
  渡邊博志、丸山徹、小田切優樹, 他
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Carbon monoxide binding red blood cells prevent cytochrome p450 degradation in resuscitation after hemorrhagic shock in a rat model2011
- Author(s)
  Shigeru Ogaki, Masaki Otagiri, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 尿毒症物質p-cresyl sulfateの酸化ストレスに及ぼす影響2011
- Author(s)
  本田大輔、宮本洋平、渡邊博志、門脇大介、丸山徹、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] MS解析を用いた慢性肝炎時におけるヒト血清アルブミンのレドックス解析と構造及び機能との関連性2011
- Author(s)
  南雲恒平、杉森剛志、窪田和幸、山田尚之、異島優、渡邊博志、田申基彦、佐々木裕、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Quantitative Analysis of Cysteine-34 on the Anitioxidative Properties of Human Serum Albumin and its Physiological Significance in Hemodialysis Patients2011
- Author(s)
  Makoto Anraku, Masaki Otagiri, et al.
- Organizer
  Helsinki Drug Research 2011 Congress
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] MS解析を用いた慢性肝炎時におけるヒト血清アルブミンのレドックス解析と構造及び機能との関連性2011
- Author(s)
  南雲恒平、杉森剛志、窪田和幸、山田尚之、異島優、渡邊博志、田中基彦、佐々木裕、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Carbon monoxide binding red blood cells prevent cytochrome p450 degradation in resuscitation after hemorrhagic shock in a rat model2011
- Author(s)
  Ogaki S, Otagiri M, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Albumin Fusion of Thioredoxin : Evaluation of Its Biological Activity for Potential Therapeutic Applications2011
- Author(s)
  Otagiri M
- Organizer
  8th Retro metabolism Based Drug Design and Targeting Conference
- Place of Presentation
  Graz, Austria
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 高尿酸血症治療薬ベンズプロマロンの抗酸化作用評価2011
- Author(s)
  坂口翔一、宮本洋平、佐藤圭創、丸山徹、小田切優樹、平田純生、門脇大介
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Interaction between p-cresyl sulfate and indoxyl sulfate during body disposition can influence their serum free concentrations in chronic kidney disease2011
- Author(s)
  Watanabe H, Otagiri M, et al.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発メカニズム2011
- Author(s)
  宮本洋平、岩尾康範、米良克美、渡邊博志、門脇大介、異島優、佐藤圭創、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] プレオマイシン誘発肺線維症に対するアルブミン-チオレドキシン融合体の有用性評価2011
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Quantitative Analysis of Cysteine-34 on the Anitioxidative Properties of Human Serum Albumin and its Physiological Significance in Hemodialysis Patients2011
- Author(s)
  Anraku M, Otagiri M, et al
- Organizer
  Helsinki Drug Research 2011 Congress
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 抗酸化作用に対するオルメサルタンとアゼルニジピンの併用効果2011
- Author(s)
  末永綾香、麻生美紗子、宮本洋平、門脇大介、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 一酸化炭素結合型赤血球による肝CYP保護効果2011
- Author(s)
  大柿滋、田口和明、渡邊博志、門脇大介、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Improved therapeutic effect of thioredoxin by fusing to human serum albumin against ovalbumin-induced lung injury2011
- Author(s)
  Ryota Tanaka, Masaki Otagiri, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Quantitative assessment of cysteinylated human serum albumin using ESI-TOF/MS and its clinical significance in chronic liver disease2011
- Author(s)
  Nagumo K, Otagiri M, et al.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 112位と114位のアミノ酸残基はα1・酸性糖タンパク質バリアント間の薬物結合選択機構に寄与する2011
- Author(s)
  丸山徹、和泉実代子、中村照也、西弘二、小野知実、渡邊博志、山縣ゆり子、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素結合型赤血球による肝CYP保護効果2011
- Author(s)
  大柿滋、田口和明、渡邊博志、門脇大介、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 尿毒症物質p-cresyl sulfateの酸化ストレスに及ぼす影響2011
- Author(s)
  本田大輔、宮本洋平、渡邊博志、門脇大介、丸山徹、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Interaction between p-cresyl sulfate and indoxyl sulfate during body disposition can influence their serum free concentrations in chronic kidney disease2011
- Author(s)
  Hiroshi Watanabe, Masaki Otagiri, et al
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury2011
- Author(s)
  Yu Ishima, Masaki Otagiri, et al
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Effect of genetically mannosylated-human serum albumin with nitric oxide on hepatic ischemia reperfusion injury2011
- Author(s)
  Yu Ishima, Masaki Otagiri, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 高尿酸血症治療薬ベンズプロマロンの抗酸化作用評価2011
- Author(s)
  坂口翔一、宮本洋平、佐藤圭創、丸山徹、小田切優樹、平田純生、門脇大介
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 抗酸化作用に対するオルメサルタンとアゼルニジピンの併用効果2011
- Author(s)
  末永綾香、麻生美紗子、宮本洋平、門脇大介、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Characterization of structure and function of human serum albumin in patients with liver disease2011
- Author(s)
  Nagumo K, Otagiri M, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Involvement of hemoglobin beta-chain on plasma membrane in uptake of human alpha1-acid glycoprotein into liver2011
- Author(s)
  Hisakazu Komori, Masaki Otagiri, et al
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素結合型赤血球による肝CYP保護効果2011
- Author(s)
  大柿滋、田口和明、渡邊博志、門脇大介、小田切優樹、丸山徹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡,グランシップ
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Poly-SNO-アルブミンによる抗癌剤耐性克服効果2011
- Author(s)
  渡邊博志、原茉梨絵、異島優、末永綾香、丸山徹、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Quantitative assessment of cysteinylated human serum albumin using ESI-TOF/MS and its clinical significance in chronic liver disease2011
- Author(s)
  Nagumo K, Otagiri M, et al
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 112位と114位のアミノ酸残基はα1-酸性糖タンパク質バリアント間の薬物結合選択機構に寄与する2011
- Author(s)
  丸山徹、和泉実代子、中村照也、西弘二、小野知実、渡邊博志、山縣ゆり子、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発メカニズム2011
- Author(s)
  宮本洋平、岩尾康範、米良克美、渡邊博志、門脇大介、異島優、佐藤圭創、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Involvement of hemoglobin beta-chain on plasma membrane in uptake of human alpha1-acid glycoprotein into liver2011
- Author(s)
  Hisakazu Komori, Masaki Otagiri, et al.
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Acute-phase protein alpha1-acid glycoprotein acquires anti-bacterial activity through S-nitrosylation by a nitric oxide-dependent mechanism2011
- Author(s)
  Kaori Watanabe, Masaki Otagiri, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] A peptide moiety of human α1-acid glycoprotein is recognized by the hemoglobin β-chain on mouse liver parenchymal cells2011
- Author(s)
  Suenaga T, Otagiri M, et al
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] プレオマイシン誘発肺線維症に対するアルブミン-チオレドキシン融合体の有用性評価2011
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Characterization of structure and function of human serum albumin in patients with liver disease2011
- Author(s)
  Nagumo K, Otagiri M, et al.
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 臓器移植保存液としてのS-ニトロソ化アルブミンの有用性評価2011
- Author(s)
  品川拓也, 異島優, 米重梓二, 末永綾香, 渡邊博志, 丸山徹, 小田切優樹
- Organizer
  第18回日本血液代替物学会年次大会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23390142
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発メカニズム2011
- Author(s)
  宮本洋平、岩尾康範、米良克美、渡邊博志、門脇大介、異島優、佐藤圭創、小田切優樹、丸山徹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury2011
- Author(s)
  Ishima Y, Otagiri M, et al.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Improved therapeutic effect of thioredoxin by fusing to human serum albumin against ovalbumin-induced lung injury2011
- Author(s)
  Ryota Tanaka, Masaki Otagiri, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics2011
- Author(s)
  Toru Maruyama, Masaki Otagiri, et al.
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] A peptide moiety of human α1-acid glycoprotein is recognized by the hemoglobin2011
- Author(s)
  Suenaga T, Otagiri M, et al.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Malaysia, Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] 出血性ショックモデルラットにおけるヘモグロビン小胞体頻回投与時での体内動態について2011
- Author(s)
  田口和明、渡邊博志、酒井宏水、丸山徹、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Albumin Fusion of Thioredoxin: Evaluation of Its Biological Activity for Potential Therapeutic Applications2011
- Author(s)
  Masaki Otagiri
- Organizer
  8th Retro metabolism Based Drug Design(招待講演)
- Place of Presentation
  Graz, Austria
- Data Source
  KAKENHI-PROJECT-23659088
[Presentation] Effect of genetically mannosylated-human serum albumin with nitric oxide on hepatic ischemia reperfusion injury2011
- Author(s)
  Ishima Y, Otagiri M, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 出血性ショックモデルラットにおけるヘモグロビン小胞体頻回投与時での体内動態について2011
- Author(s)
  田口和明、渡邊博志、酒井宏水、丸山徹、小田切優樹
- Organizer
  日本薬学会年会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics2011
- Author(s)
  Maruyama T, Otagiri M, et al
- Organizer
  2011 AAPS Annual Meeting and Exposition
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Acute-phase protein alphal-acid glycoprotein acquires anti-bacterial activity through S-nitrosylation by a nitric oxide-dependent mechanism2011
- Author(s)
  Kaori Watanabe, Masaki Otagiri, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] The uremic solute indoxyi sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions2011
- Author(s)
  Yohei Miyamoto, Masaki Otagiri, et al
- Organizer
  4th Asia Pacific Regional ISSX Meeting
- Place of Presentation
  Tainan. Taiwan
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] CHARACTERIZATION OF STRUCTURE AND FUNCTION OF HUMAN SERUM ALBUMIN IN PATIENTS WITH LIVER DISEASE2010
- Author(s)
  Kohei Nagumo, Tsuyoshi Sugimori, Motohiko Tanaka, Yutaka Sasaki, Yu Ishima, Hiroshi Watanabe, Kazuyuki Kubota, Naoyuki Yamada, Masaki Otagiri, Toru Maruyama.
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] S-ニトロソ化α_1-酸性糖タンパク質の抗菌活性評価2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] α1-acid glycoprotein enhances the expression of hemoglobin scavenge receptor CD163 through the activation of TLR4 signaling2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第4回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] CHARACTERIZATION OF STRUCTURE AND FUNCTION OF HUMAN SERUM ALBUMIN IN PATIENTS WITH LIVER DISEASE2010
- Author(s)
  Kohei Nagumo, Tsuyoshi Sugimori, Motohiko Tanaka, Yutaka Sasaki, Yu Ishima, Hiroshi Watanabe, Kazuyuki Kubota, Naoyuki Yamada, Masaki Otagiri, Toru Maruyama.
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] α_1-酸性糖タンパク質はS-ニトロソ化により抗菌活性を獲得する2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 尿毒症物質CMPFの生体内レドックス特性2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  第27回臨床フリーラジカル会議
- Place of Presentation
  京都,烟川
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Hepatic uptake of alfal-acid glycoprotein through hemoglobin beta-chain-mediated endocytic pathway2010
- Author(s)
  Komori H, Uehara N, Nishi K, Watanabe H, Maruyama T, Otagiri M
- Organizer
  9^<th> International ISSX meeting
- Place of Presentation
  Istanbul
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発機序解明2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  第25回日本薬剤学会
- Place of Presentation
  あわぎんホール徳島県郷土文化会館
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] チオレドキシンとアルブミン融合体の作製と生物活性の評価2010
- Author(s)
  小田切優樹, 生田祥太郎、Tuan Giam Chung Victor, 異島優, 中城圭介, 古川真斗, 渡邊博志, 丸山徹
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 尿毒症物質CMPFの生体内レドックス特性2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  第27回臨床フリーラジカル会議
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Poly-SNO-アルブミンによる抗癌剤多剤耐性克朋効果2010
- Author(s)
  原茉梨絵、異島優、末永綾香、丸山徹、小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 出血性ショックモデルラットにおける一酸化炭素結合型赤血球の肝チトクロームP450保護効果2010
- Author(s)
  大柿滋、田口和明、渡邊博志、小田切優樹、丸山徹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] PROTECTIVE EFFECT OF S-NITROSYLATED HUMAN SERUM ALBUMINS TO ORGAN INJURY2010
- Author(s)
  Shinji Yoneshige, Yu Ishima, Ayaka Suenaga, Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] Involvement of hemoglobin b-chain on plasma membrane in uptake of human al-acid glycoprotein into liver2010
- Author(s)
  Komori H, Uehara N, Nishi K, Watanabe H, Maruyama T, Otagiri M
- Organizer
  The Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] BLM誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2010
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] ヘモグロビン小胞体の体内動態特性に基づく安全性評価2010
- Author(s)
  田口和明, 丸山徹, 小田切優樹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素を付加した赤血球は大量出血時における肝チトクロームP450を保護する2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] S-ニトロソ化α_1-酸性糖タンパク質の抗菌活性評価2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] α1-酸性糖タンパク質によるCD163の発現誘導2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第35回西日本薬剤学研究会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] IMPROVED THERAPEUTIC EFFECT OF THIOREDOXIN BY FUSION TO HUMAN SERUM ALBUMIN AGAINST BLEOMYCIN-INDUCED PULMONARY FIBROSIS2010
- Author(s)
  田中遼大, 古川真斗, 異島優, 田中健一郎, 水島徹, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] α_1-酸性糖タンパク質の薬物結合部位に関する構造生物学的研究2010
- Author(s)
  和泉実代子、中村照也、小野知実、渡邊博志、山縣ゆり子、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎大学薬学部
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Poly-SNO-アルブミンによる抗癌剤多剤耐性克朋効果2010
- Author(s)
  原茉梨絵、異島優、末永綾香、丸山徹、小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] ファージディスプレイ法を用いたHSA分子上のBR結合部位の探索2010
- Author(s)
  蓑毛藍、小田切優樹, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素結合型赤血球による肝チトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邊博志、小田切優樹、丸山徹
- Organizer
  第25回日本薬剤学会
- Place of Presentation
  あわぎんホール徳島県郷土文化会館
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] 出血性ショックモデルラットにおける一酸化炭素結合型赤血球のチトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] α_1-酸性糖タンパク質の薬物結合部位に関する構造生物学的研究2010
- Author(s)
  和泉実代子、中村照也、小野知実、渡邊博志、丸山徹、山縣ゆり子、小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] α_1-酸性糖タンパク質の薬物結合部位に関する構造生物学的研究2010
- Author(s)
  和泉実代子、中村照也、小野知実、渡邊博志、山縣ゆり子、小田切優樹、丸山徹
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  長崎大学
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] チオレドキシンとアルブミン融合体の作製と生物活性の評価2010
- Author(s)
  小田切優樹
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590054
[Presentation] POLY-S-NITROSYLATED HUMAN SERUM ALBUMIN REVERTS THE RESIS TANCE TO DOXORUBICIN IN HUMAN MYELOGENOUS LEUKEMIC CELLS2010
- Author(s)
  原茉梨絵、異島優、末永綾香、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] ヘモグロビン小胞体の体内動態と慢性肝障害の関係に関する検討2010
- Author(s)
  田口和明, 宮里麻友美, 渡邊博志, 土田英俊, 小林紘一, 丸山徹, 小田切優樹
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] α_1-酸性糖タンパク質はS-ニトロソ化により抗菌活性を獲得する2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] X-RAY CRYSTALLOGRAPHIC STUDY OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND DRUG COMPLEX2010
- Author(s)
  Miyoko Izumi., Tomomi Ono, Teruya Nakamura, Koji Nishi, Hiroshi Watanabe, Toru Maruyama, Yuriko Yamagata, Masaki Otagiri
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Effect OF combination treatment of Azelnidipine on Antioxidative activity of Ol mesaltan In human vascular endothelial cells2010
- Author(s)
  Misako Aso, Yohei Miyamoto, Daisuke Kadowaki, Hiroshi Watanabe, Ayaka Suenaga, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発機序解明2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] alfa1-acid glycoprotein enhances the expression of hemoglobin scavenge receptor CD163 through the activation of TLR4 signaling2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第4回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] POLY-S-NITROSYLATED HUMAN SERUM ALBUMIN REVERTS THE RESISTANCE TO DOXORUBICIN IN HUMAN MYELOGENOUS LEUKEMIC CELLS2010
- Author(s)
  原茉梨絵、異島優、末永綾香、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] α_1-酸性糖タンパク質はS-ニトロソ化により抗菌活性を獲得する2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 出血性ショックモデルラットにおける一酸化炭素結合型赤血球のチトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] チオレドキシンとアルブミン融合体の作製と生物活性の評価2010
- Author(s)
  小田切優樹, 生田祥太郎, Tuan Giam Chung Victor, 異島優, 中城圭介, 古川真斗, 渡邊博志, 丸山徹
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] α1-acid glycoprotein enhances the expression of hemoglobin scavenge receptor CD163 through the activation of TLR4 signaling2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第4回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] PROTECTIVE EFFECT OF S-NITROSYLATED HUMAN SERUM ALBUMINS TO ORGAN INJURY2010
- Author(s)
  Shinji Yoneshige, Yu Ishima, Ayaka Suenaga, Hiroshi Watanabe, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素を付加した赤血球は大量出血時における肝チトクロームP450を保護する2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] CHARACTERIZATION OF STRUCTURE AND FUNCTION OF HUMAN SERUM ALBUMIN IN PATIENTS WITH LIVER DISEASE2010
- Author(s)
  Kohei Nagumo, Tsuyoshi Sugimori, Motohiko Tanaka, Yutaka Sasaki, Yu Ishima, Hiroshi Watanabe, Kazuyuki Kubota, Naoyuki Yamada, Masaki Otagiri, Toru Maruyama.
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] X-RAY CRYSTALLOGRAPHIC STUDY OF HUMAN ALPHA1-ACID GLYCOP ROTEIN AND DRUG COMPLEX2010
- Author(s)
  Miyoko Izumi, Tomomi Ono, Teruya Nakamura, Koji Nishi, Hiroshi Watanabe, Toru Maruyama, Yuriko Yamagata, Masaki Otagiri
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 臓器障害に対する各種SNO-HSAの保護効果2010
- Author(s)
  米重梓二、異島優、末永綾香、渡邊博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] α_1-酸性糖タンパク質はS-ニトロソ化により抗菌活性を獲得する2010
- Author(s)
  渡辺佳織, 異島優, 末永綾香, 渡邊博志, 甲斐俊哉, 丸山徹, 小田切優樹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] α_1-酸性糖タンパク質の薬物結合部位に関する構造生物学的研究2010
- Author(s)
  和泉実代子、中村照也、小野知実、渡邊博志、丸山徹、山縣ゆり子、小田切優樹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] ヘモグロビン小胞体の出血性ショックモデルラットにおける大腸菌増殖抑制効果2010
- Author(s)
  田口和明、渡邊博志、丸山徹、小田切優樹, 他
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Hepatic uptake of alfa1-acid glycoprotein through hemoglobin b-chain-mediated endocytic pathway2010
- Author(s)
  Komori H, Uehara N, Nishi K, Watanabe H, Maruyama T, Otagiri M
- Organizer
  9^<th> International ISSX meeting
- Place of Presentation
  Istanbul, Turkey Convention and Exhibition Center-Harbiye
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] オルメサルタンの抗酸化作用に及ぼすアゼルニジピンの影響2010
- Author(s)
  麻生美紗子、宮本洋平、門脇大介、渡邊博志、末永綾香、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素を付加した赤血球は大量出血時における肝チトクロームP450を保護する2010
- Author(s)
  大柿滋、田口和明、渡邊博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎大学薬学部
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] 尿毒症物質CMPFの酸化ストレス誘発機序解明2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] BLM誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2010
- Author(s)
  田中遼大, 古川真斗, 異島優, 田中健一郎, 水島徹, 渡邊博志, 小田切優樹, 丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎大学薬学部
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] BLM誘発肺線維症に対するアルブミン-チオレドキシン融合タンパク質の有用性評価2010
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] Effect OF combination treatment of Azelnidipine on Antioxidative activity of Olmesaltan In human vascular endothelial cells2010
- Author(s)
  Misako Aso, Yohei Miyamoto, Daisuke Kadowaki, Hiroshi Watanabe, Ayaka Suenaga, Masaki Otagiri, Toru Maruyama
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 糖鎖付加アルブミンを用いたクッパー細胞へのNOターゲティング2010
- Author(s)
  平田憲史朗、小田切優樹, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] ヘモグロビン小胞体の体内動態と慢性肝障害の関係に関する検討2010
- Author(s)
  田口和明, 宮里麻友美, 渡邊博志, 土田英俊, 小林紘一, 丸山徹, 小田切優樹
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] ヒトalfal-酸性糖タンパク質/薬物複合体のX線結晶構造解析2010
- Author(s)
  和泉実代子、小野知実、中村照也、西弘二、渡邊博志、丸山徹、山縣ゆり子、小田切優樹
- Organizer
  第25回日本薬剤学会
- Place of Presentation
  あわぎんホール徳島県郷土文化会館
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] α1-酸性糖タンパク質によるCD163の発現誘導2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第35回西日本薬剤学研究会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] リポソーム型人工酸素運搬体ヘモグロビン小胞体の脂質膜構成成分の安全性に関する検討2010
- Author(s)
  田口和明, 渡邊博志, 酒井宏水, 丸山徹, 小田切優樹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 出血性ショックモデルラットにおける一酸化炭素結合型赤血球の肝チトクロームP450保護効果2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] alfa1-酸性糖タンパク質によるCD163の発現誘導2010
- Author(s)
  小森久和, 渡邊博志, 首藤剛, 丸山徹, 小田切優樹
- Organizer
  第35回西日本薬剤学研究会
- Place of Presentation
  九重共同研修所
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] オルメサルタンの抗酸化作用に及ぼすアゼルニジピンの影響2010
- Author(s)
  麻生美紗子、宮本洋平、門脇大介、渡邊博志、末永綾香、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] リポソーム型人工酸素運搬体ヘモグロビン小胞体の脂質膜構成成分の安全性に関する検討2010
- Author(s)
  田口和明, 渡邊博志, 酒井宏水, 丸山徹, 小田切優樹
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 出血性ショックモデルラットにおける一酸化炭素結合型赤血球のチトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邊博志、小田切優樹、丸山徹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本国際交流会館
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] 肺障害モデルマウスに対するアルブミンチオレドキシン融合タンパク質の有用性評価2010
- Author(s)
  丸山徹、小田切優樹, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 尿毒症物質CMPFの生体内レドックス特性2010
- Author(s)
  宮本洋平、岩尾康範、渡邊博志、門脇大介、佐藤圭創、小田切優樹、丸山徹
- Organizer
  第27回臨床フリーラジカル会議
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] X-RAY CRYSTALLOGRAPHIC STUDY OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND DRUG COMPLEX2010
- Author(s)
  Miyoko Izumi, Tomomi Ono, Teruya Nakamura, Koji Nishi, Hiroshi Watanabe, Toru Maruyama, Yuriko Yamagata, Masaki Otagiri
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] ヘモグロビン小胞体の体内動態特性に基づく安全性評価2010
- Author(s)
  田口和明, 丸山徹, 小田切優樹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 1-acid glycoprotein enhances the expression of hemoglobin scavenge receptor CD163 through the activation of TLR4 signaling2010
- Author(s)
  Komori H, Watanabe H, Syuto T, Maruyama T, Otagiri M
- Organizer
  第4回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京大学武田先端知ビル
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] ヘモグロビン小胞体の出血性ショックモデルラットにおける大腸菌増殖抑制効果2010
- Author(s)
  田口和明, 渡邊博志, 酒井宏水, 堀之内宏久, 小林絋一, 丸山徹, 小田切優樹
- Organizer
  第17回日本血液代替物学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 臓器障害に対する各種SNO-HSAの保護効果2010
- Author(s)
  米重梓二、異島優、末永綾香、渡邊博志、小田切優樹、丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 肝疾患時におけるアルブミンの構造及び機能評価2010
- Author(s)
  南雲恒平, 杉森剛志, 田中基彦, 佐々木裕, 異島優, 渡邊博志, 窪田和幸, 山田尚之, 小田切優樹, 丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] IMPROVED THERAPEUTIC EFFECT OF THIOREDOXIN BY FUSION TO HUMAN SERUM ALBUMIN AGAINST BLEOMYCIN-INDUCED PULMONARY FIBROSIS2010
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] ヒトα_1-酸性糖タンパク質/薬物複合体のX線結晶構造解析2010
- Author(s)
  和泉実代子、中村照也、小野知実、渡邊博志、山縣ゆり子、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  あわぎんホール徳島郷土文化会館
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] Involvement of hemoglobin beta-chain on plasma membrane in uptake of human alfal-acid glycoprotein into liver2010
- Author(s)
  Komori H, Uehara N, Nishi K, Watanabe H, Maruyama T, Otagiri M
- Organizer
  The Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] X-RAY CRYSTALLOGRAPHIC STUDY OF HUMAN ALPHA1-ACID GLYCOPROTEIN AND DRUG COMPLEX2010
- Author(s)
  Miyoko Izumi, Tomomi Ono, Teruya Nakamura, Koji Nishi, Hiroshi Watanabe, Toru Maruyama, Yuriko Yamagata, Masaki Otagiri
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 肝疾患時におけるアルブミンの構造及び機能評価2010
- Author(s)
  南雲恒平, 杉森剛志, 田中基彦, 佐々木裕, 異島優, 渡邊博志, 窪田和幸, 山田尚之, 小田切優樹, 丸山徹
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] IMPROVED THERAPEUTIC EFFECT OF THIOREDOXIN BY FUSION TO HUMAN SERUM ALBUMIN AGAINST BLEOMYCIN-INDUCED PULMONARY FIBROSIS2010
- Author(s)
  田中遼大、古川真斗、異島優、田中健一郎、水島徹、渡邊博志、小田切優樹、丸山徹
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] ヒトa_1-酸性糖タンパク質/薬物複合体のX線結晶構造解析2010
- Author(s)
  和泉実代子、小野知実、中村照也、西弘二、渡邊博志、丸山徹、山縣ゆり子、小田切優樹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] 一酸化炭素結合型赤血球による肝チトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 一酸化炭素結合型赤血球による肝チトクロームP450の保護効果2010
- Author(s)
  大柿滋、田口和明、渡邉博志、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] alfal-酸性糖タンパク質によるCD163の発現誘導2010
- Author(s)
  Komori H, Watanabe H, Syuto T, Maruyama T, Otagiri M
- Organizer
  第35回西日本薬剤学研究会
- Place of Presentation
  大分,九重共同研修所
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] ヒトa_1-酸性糖タンパク質/薬物複合体のX線結晶構造解析2010
- Author(s)
  和泉実代子、小野知実、中村照也、西弘二、渡邊博志、丸山徹、山縣ゆり子、小田切優樹
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] イヌアルブミン分子上のケトプロフェン結合部位のトポロジー解析2009
- Author(s)
  小田切優樹
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本市民会館
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20390161
[Presentation] イヌアルブミン分子上のケトプロフェン結合部位のトポロジー解析2009
- Author(s)
  小田切優樹
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本市民会館
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21659042
[Presentation] イヌアルブミン分子上のケトプロフェン結合部位のトポロジー解析2009
- Author(s)
  小田切優樹
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本市民会館
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21390177
[Presentation] 血清タンパク質の分子薬剤学的解明と医薬への応用2008
- Author(s)
  小田切優樹
- Organizer
  日本薬学会(薬学会賞受賞講演)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19659138
[Presentation] 薬学会賞受賞講演, 血清タンパク質の分子薬剤学的解明と医薬への応用2008
- Author(s)
  小田切優樹
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18390051
[Presentation] 血清タンパク質の分子薬剤学的解明と医薬への応用2008
- Author(s)
  小田切優樹
- Organizer
  日本薬学会 (薬学会賞受賞講演)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18390051
[Presentation] OAT-dependent cellular accumulation of p-cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress
- Author(s)
  Hiroshi Watanabe, Yohei Miyamoto, Yuki Enoki, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri and Toru Maruyama
- Organizer
  19th North American ISSX Meeting and 29th JSSX Meeting
- Place of Presentation
  Hilton San Francisco, California, USA
- Year and Date
  2014-10-20 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] 尿毒症物質 p‐クレジル硫酸の酸化ストレス誘導を介した血管障害作用
- Author(s)
  渡邊　博志、宮本　洋平、榎木　裕紀、異島　優、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25460652
[Presentation] Antioxidant and renoprotective activity of 2-hydroxypropyl-beta-cyclodextrin in nephrectomized rats
- Author(s)
  Anraku M, Iohara D, Uekama K,Otagiri M, Hirayama F.
- Organizer
  19th North American ISSX Meeting / 29th JSSX Meeting
- Place of Presentation
  サンフランシスコ（USA）
- Year and Date
  2014-10-19 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 尿毒症物質インドキシル硫酸の酸化修飾体に関する構造特性と生物活性
- Author(s)
  丸山　徹、異島　優、成底　徹、小谷　俊介、中島　誠、渡邊　博志、小田切　優樹
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] Renal Drug Delivery Systemを可能とする腎標的化ペプチドの網羅的探索
- Author(s)
  戸田　翔太、渡邊　博志、弥永　直樹、濱崎　慶輔、國安　明彦、異島　優、小田切　優樹、丸山　徹
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] キチンナノファイバーを利用した徐放性素材への応用
- Author(s)
  平賀歩，安楽誠，庵原大輔，伊福伸介，小田切優樹, 平山文俊
- Organizer
  第28回キチン・キトサンシンポジウム
- Place of Presentation
  順天堂大学（東京都、文京区）
- Year and Date
  2014-08-07 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] アルブミン-チオレドキシン融合体によるシスプラチン腎症予防効果
- Author(s)
  小玉　あずさ、渡邊　博志、田中　遼大、近藤　真澄、WU　Qiong、遠藤　正之、異島　優、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 透析患者における新規酸化ストレスマーカーとしてのシステイン付加Cys34アルブミンの有用性評価
- Author(s)
  今福　匡史、南雲　恒平、杉森　剛志、阿部　貴弥、申　曽洙、渡邊　博志、山田　尚之、田中　元子、松下　和孝、小田切　優樹、丸山　徹
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] OAT-dependent cellular accumulation of p-cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress.
- Author(s)
  Hiroshi Watanabe, Yohei Miyamoto, Yuki Enoki, Yu Ishima, Masafumi Fukagawa, Masaki Otagiri and Toru Maruyama
- Organizer
  19th North American ISSX Meeting and 29th JSSX Meeting
- Place of Presentation
  Hilton San Francisco, California, USA
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] 健康食品の腎不全治療への応用：透析患者におけるキトサンの抗酸化作用の定量的解析
- Author(s)
  安楽誠, 田中元子，南雲恒平，渡邊博志，庵原大輔，平山文俊，丸山徹，小田切優樹
- Organizer
  第24回日本医療薬学会年会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 慢性腎不全モデルラットにおける2-ヒドロキシプロピル-β-シクロデキストリンの腎保護及び酸化ストレス抑制効果
- Author(s)
  平賀歩, 安楽誠, 和田幸樹, 庵原大輔, 小田切優樹, 上釜兼人, 平山文俊
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（埼玉県、さいたま市）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] 尿毒症物質 p‐クレジル硫酸の酸化ストレス誘導を介した血管障害作用
- Author(s)
  渡邊　博志、宮本　洋平、榎木　裕紀、異島　優、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] Therapeutic Applications of Albumin-Thioredoxin Fusion Protein.
- Author(s)
  Masaki Otagiri
- Organizer
  10th European Symposium on Biochemical Engineering Sciences and 6th International Forum on Industrial Bioprocesses Lille
- Place of Presentation
  Lille (France)
- Year and Date
  2014-09-07 – 2014-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-24390043
[Presentation] 酸化ストレス関連疾患とトランスレーショナルリサーチ
- Author(s)
  渡邊　博志、南雲　恒平、田中　遼大、小玉　あずさ、異島　優、山田　尚之、瀬戸山　博子、田中　基彦、佐々木　裕、田中　元子、深川　雅史、小田切　優樹、丸山　徹
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本大学薬学部
- Year and Date
  2014-11-15 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-25460190
[Presentation] キトサン－シクロデキストリン複合体を利用した徐放性素材への応用
- Author(s)
  安楽誠, 平賀歩, 髙良裕, 前崎祐二, 小田切優樹, 庵原大輔, 平山文俊
- Organizer
  第28回キチン・キトサンシンポジウム
- Place of Presentation
  順天堂大学（東京都、文京区）
- Year and Date
  2014-08-07 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] スルホブチル-β-シクロデキストリンによるキトサンナノファイバーゲルの調製
- Author(s)
  安楽誠，平賀歩，庵原大輔，伊福伸介，小田切優樹, 平山文俊
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県、神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460248
[Presentation] Therapeutic Applications of Albumin-Thioredoxin Fusion Protein.
- Author(s)
  Masaki Otagiri
- Organizer
  10th European Symposium on Biochemical Engineering Sciences and 6th International Forum on Industrial Bioprocesses Lille
- Place of Presentation
  Lille (France)
- Year and Date
  2014-09-07 – 2014-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-25670085

1. MARUYAMA Toru (90423657)

# of Collaborated Projects: 16 results

# of Collaborated Products: 375 results
2. WATANABE Hiroshi (70398220)

# of Collaborated Projects: 10 results

# of Collaborated Products: 274 results
3. ISHIMA Yu (00457590)

# of Collaborated Projects: 6 results

# of Collaborated Products: 77 results
4. IMAMURA Yorishige (30040314)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. IMAI Teruko (70176478)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. TANASE Sumio (20112401)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
7. Ayaka Suenaga (20040313)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
8. KAI Hirofumi (30194658)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. AKAIKE Takaaki (20231798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. MORIOKA HIROSHI (20230097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. GOYA Shujiro (50004560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 田口和明 (90621912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
13. 石田竜弘 (50325271)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
14. YAMASAKI Keishi (30435143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. KOBASHIGAWA Yoshihiro (90455600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUWA Yoshiaki (50516127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. NAKAYAMA Hitoshi (70088863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NISHI Katsuhide (00040220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. UNO Tadayuki (00183020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MAEDA Hiroshi (90004613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KAWAHARA Koichi (10347015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ANRAKU Makoto (60398245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
23. UEKAMA Kaneto (90040328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
24. 藤山重俊 (20109656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 猪股裕紀洋 (50193628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NAKAGAMI Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KUWATA Shigeki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. NOZAKI Syuei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. IFUKU Shinsuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. IHARA Hideshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. KADOWAKI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. NAOE Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. WATANABE Takehisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 前田仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 小森久和

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 澤智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. 平田純生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 國安明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 佐々木裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OTAGIRI Masaki 小田切 優樹

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Development of Innovative Antibody Drugs using Multifunctional Albumin as a Carrier for Low-molecular-weight AntibodiesPrincipal Investigator

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Development of novel hybrid anti-oxidant based on albumin fusion technology and its therapeutic application on acute radiation syndromePrincipal Investigator

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Construction of an Innovative Bone Marrow Delivery System of Anticancer Drug for Control of Malignant Tumors' Bone MetastasisPrincipal Investigator

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Design and Evaluation of Next Generation Albumin-thioredoxin Fusion Protein for Multiple Organ Failure TreatmentPrincipal Investigator

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OTAGIRI Masaki 小田切優樹