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Saito Kuniaki  齋藤 邦明

ORCIDConnect your ORCID iD *help
… Alternative Names

SAITOU Kuniaki  齋藤 邦明

SAITO Kuniaki  斉藤 邦明

斉藤 邦明  サイトウ クニアキ

齋藤 邦昭  サイトウ クニアキ

齋藤 邦明  サイトウ クニアキ

SAITOH Kunio  斎藤 邦明

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Researcher Number 80262765
Other IDs
External Links
Affiliation (Current) 2025: 藤田医科大学, 医療科学研究科, 教授
Affiliation (based on the past Project Information) *help 2024 – 2025: 藤田医科大学, 医療科学研究科, 教授
2018 – 2024: 藤田医科大学, 保健学研究科, 教授
2018: 藤田医科大学, 大学院・医療科学部, 教授
2016 – 2017: 藤田保健衛生大学, 医療科学部, 教授
2015 – 2017: 藤田保健衛生大学, 保健学研究科, 教授 … More
2016: 藤田保健衛生大学, 大学院・医療科学部, 教授
2010 – 2014: 京都大学, 医学(系)研究科(研究院), 教授
2008 – 2013: Kyoto University, 医学研究科, 教授
2012: 京都大学, 大学院・医医学系研究科, 教授
2012: 京都大学, 大学院・医学研究科, 教授
2009 – 2011: 京都大学, 医学系研究科, 教授
2007: Gifu University, Graduate School of Medicine, Asociate Professor
2007: Gifu University, Graduate School of Medicine, Part-time Lecturer
2006: 岐阜大学, 大学院医学系研究科, 助教授
2005: 岐阜大学, 大学院・医学系研究科, 助教授
2002: Gifu University Hospital, Assistant Professor, 医学部附属病院, 講師
1999 – 2001: Gifu University Hospital; Assistant Professor, 医学部・附属病院, 講師
1997 – 1998: Gifu University, University Hospital, Assistant Professor, 医学部附属病院, 講師
1997: 岐阜大学, 医学部・附属病院, 講師
1994 – 1996: 岐阜大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Laboratory medicine / Neurochemistry/Neuropharmacology / Basic Section 49030:Experimental pathology-related / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied health science / Applied health science / Laboratory medicine
Except Principal Investigator
Laboratory medicine / Laboratory medicine … More / Circulatory organs internal medicine / Orthopaedic surgery / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 52030:Psychiatry-related / Basic Section 54030:Infectious disease medicine-related / Basic Section 52040:Radiological sciences-related / Basic Section 53040:Nephrology-related / Experimental pathology / Psychiatric science / Hematology / Medical pharmacy / Metabolomics / Cerebral neurosurgery / Fundamental nursing / Gastroenterology Less
Keywords
Principal Investigator
サイトカイン / TNF-α / AIDS / 脳神経疾患 / 先制医療 / バイオマーカー / ストレス / 抑うつ / 痴呆 / 炎症 … More / 時系列データベース / 生活習慣病予測モデル / 暦年的データベース / 機械学習 / 生活習慣病 / 出生時体重 / 周産期栄養状態 / 周産期うつ / 産後うつ病 / トリプトファン代謝 / アミノ酸代謝 / 周産期うつ病 / メタボローム / ビックデータ / ビッグデータ解析 / トリプトファン代謝産物 / inflammatory neurological disorders / NO synthase / indoleamine-2, 3-dioxygenase / dementia / トキソプラズマ / 炎症性脳神経疾患 / NO合成酵素 / indoleamine-2,3-dioxygenase / Osteoarthritis;OA / Rheumatoid arthritis;RA / Progranulin;PGRN / 関節リウマチ / プログラニュリン / 心身の健康 / インターネット / 健康科学 / うつ病 / 酵素誘導 / 病態検査学 / コンパニオン診断 / ウイルス性肝炎 / IDO / トリプトファン / インターフェロン / 臨床化学 / 炎症・免疫 / 生理活性物質 / 臨床検査医学 / ノックアウトマウス / エイズ / 記憶 / 組織修復 / アポリポタンパク … More
Except Principal Investigator
Atherosclerosis / トリプトファン代謝 / TNF-α / サイトカイン / ノックアウトマウス / バイオマーカー / Cytokine / メタボロミクス / うつ病 / IDO2 / プロテオミクス / Knockout mouse / Bone marrow transplantation / Macrophage / MCP-1 / VCAM-1 / ICAM-1 / マクロファージ / 動脈硬化 / Apoptosis / knockout mice / interleukin-1 / tumor necrosis factor-α / interferon-γ / encephalomyocarditis virus / 高脂血症 / 慢性関節リウマチ / 腫瘍 / IDO / 遺伝子解析 / 液性免疫 / SARS-CoV-2 / 末梢免疫細胞 / 炎症性サイトカイン / 免疫応答 / うつ病バイオマーカー / 骨髄由来免疫抑制細胞MDSC / 炎症系サイトカイン / ワクチン療法 / ワクチン / HBV / 深層学習 / 特発生間質性肺炎 / 敵対的生成ネットワーク / 人工知能 / 病理画像 / CT画像 / 画像分類 / 画像生成 / 特発性間質性肺炎 / 疾患モデル / キヌレニン / トリプトファン / NMDA受容体拮抗薬 / NMDA受容体 / 尿細管障害 / 糖尿性腎臓病 / メタボローム解析 / トリプトファン代謝物 / 糖尿病性腎臓病 / 糖尿病性腎症 / 免疫機能 / インドールアミン酸素添加酵素2 / 免疫調節因子 / 炎症 / 網羅的解析 / りん酸化タンパク質 / オミックス解析 / 塩分摂取 / 環境因子 / メタボローム / 多発性嚢胞腎症 / 多発性嚢胞腎 / リン酸化 / 慢性腎臓病 / MAGE-D1 / 診断バイオマーカー / 精神薬理学 / うつ様症状 / 疼痛性障害 / ユビキチン化セロトニントランスポーター / ユビキチン化 / セロトニントランスポーター / 診断 / うつ / 慢性炎症 / GP88 / TNF / 悪性リンパ;腫 / progranulin / GP88 / 悪性リンパ腫 / 自閉症 / SV2A / レベチラセタム / 自閉症スペクトラム障害 / 細胞増殖 / 腫瘍免疫 / rhabdomvosis / statin drugs / hyperlipidemia / 横紋筋融解症 / スタチン系薬剤 / clinical test / biomarker / clinical proteome / プロテオーム / 質量分析 / 臨床検査 / 臨床プロテオーム / Proteomics / macrophage / proteomics / chemokines / cell adhesion molecules / inflammatory cell infiltration / NE-κB / transgenic mice / reperfusion injury / ischemia / 好中球 / 再灌流障害 / 心筋虚血 / ケモカイン / 接着因子 / 炎症細胞浸潤 / NF-κB / トランスジェニックマウス / 再灌流傷害 / Cytokines / Knockout Mice / Apolipoprotein E / アポリポ蛋白E / pre βHDL / Corobary heart disease / Lipid-free-free apolipoprotein / preβ HDL / ELISA / Coronary heart disease / pre β HDL / Coronary heart desease / Lipid-free apolipoprotein / Soluble Fas / Rheumatoid arthritis / 慢性関節リウマチ(RA) / Fas蛋白 / アポトーシス / cytokine / viral myocarditis / IL-1β / INF-α / IFN-γ / interleukin-6 / ウィルス心筋炎 / ウイルス心筋炎 / Hyperlipidemia / Polymorphism / Apo A-IV / 遺伝子多型性 / アポA-IV / immunotherapy / retrovirus / lymphocyte phenotypes / soluble interleukin-2 receptor / rheumatoid arthritis / レトロウイルス / 接着分子 / 可溶性L-selectin / インターロイキン2 / レトロウィルス / Angiogenesis / Proliferation / Migration / Endothelial cell / Tissue repair / Immunohistochemistry / Acute phase reactant / Lipoprotein (a), Lp (a) / アポ(a)イソ型 / 遊走及び増殖 / 血管新生 / 増殖 / 遊走 / 血管内皮細胞 / 組織修復 / 免疫組織化学 / 急性相反応 / リポ蛋白(a) / Allele number / Genotype / Phenotype / structural heterogeneity / Apolipoprotein(a) / Lp(a) lipoprotein / 制限酵素Swa I / 制限酵素Kpn I / アポ(a)表現型 / アポ(a)遺伝子型 / ジェノタイプ / フェノタイプ / allele number / 遺伝型 / 表現型 / 構造変異性 / アポ(a) / Lp(a)リポ蛋白 / α- ガラクトシルセラミド / NKT細胞免疫療法 / α-ガラクトシルセラミド / インドールアミン酸素添加酵素 / MRI / MRI / 頸動脈内膜剥離術 / 頸動脈プラーク / IDO / 脳血管障害学 / CPTII遺伝子 / FACS / フローサイトメトリー / リアノジン受容体 / 細胞内カルシウム / 筋障害 / スタチン製剤 / IgA / クロモグラニン / がん患者のストレス / STAI / POMS / ストレスホルモン / ストレス緩和 / 色彩映像 / 生存率 / LPS / ガラクトースアミン / IL-6 / TNF / 急性肝障害モデル / 骨髄移植 Less
  • Research Projects

    (40 results)
  • Research Products

    (232 results)
  • Co-Researchers

    (76 People)
  •  乾癬におけるトリプトファン代謝に着目した病態解明と制御法の開発Principal Investigator

    • Principal Investigator
      齋藤 邦明
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Fujita Health University
  •  Mechanisms of peripheral-CNS immune responses in the development of major depressive disorder induced by stress

    • Principal Investigator
      鍋島 俊隆
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Fujita Health University
  •  多角的なSARS-CoV-2免疫獲得状況の調査研究

    • Principal Investigator
      藤垣 英嗣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Fujita Health University
  •  トリプトファン代謝制御を利用した慢性HBV感染症に対する治療的ワクチン療法の開発

    • Principal Investigator
      伊藤 弘康
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Fujita Health University
  •  時系列データベースを活用した生活習慣病予測モデルの構築および検証Principal Investigator

    • Principal Investigator
      齋藤 邦明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Fujita Health University
  •  Development of a new diagnostic technique for idiopathic interstitial pneumonia based on a synthesis of patient images

    • Principal Investigator
      Teramoto Atsushi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Fujita Health University
  •  Elucidation of the role of tryptophan metabolism in diabetic nephropathy: Towards a development of novel treatment of diabetic nephropathy targeting tryptophan metabolism

    • Principal Investigator
      Yuzawa Yukio
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Fujita Health University
  •  Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.Principal Investigator

    • Principal Investigator
      Saito Kuniaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      Fujita Health University
  •  Analysis of carcinogenesis originated from chronic inflammation in malignant lymphoma

    • Principal Investigator
      Tsurumi Hisashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Gifu University
  •  Development of the next-generation diagnosis method for depression by using byomakers based on pathophysiological mechanism

    • Principal Investigator
      Nabeshima Toshitaka
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Fujita Health University
  •  Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through regulation of IL-6/stat3 signalling

    • Principal Investigator
      Yamamoto Yasuko
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Laboratory medicine
    • Research Institution
      Fujita Health University
  •  Tryptophan metabolic profile is effective for preemptive medicine in depression symptomsPrincipal Investigator

    • Principal Investigator
      Saito Kuniaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied health science
    • Research Institution
      Fujita Health University
  •  Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-

    • Principal Investigator
      Nagao Shizuko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Fujita Health University
  •  Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.Principal Investigator

    • Principal Investigator
      SAITO Kuniaki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Fujita Health University
      Kyoto University
  •  Antitumor efficacies of indoleamine 2,3-dioxygenase 2 in lewis lung carcinoma mice model.

    • Principal Investigator
      Yamamoto Yasuko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Fujita Health University
      Kyoto University
  •  The role of synaptic vesicle protein 2A (SV2A) in the pathophysiology and treatment of Autism spectrum disorders

    • Principal Investigator
      MORIYA Yuka
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Meijo University
  •  The investigation of immune regulation by IDO in NKT cell-mediated immunotherapy

    • Principal Investigator
      HOSHI Masato
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Laboratory medicine
    • Research Institution
      Suzuka University of Medical Science
  •  Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depressionPrincipal Investigator

    • Principal Investigator
      SAITO KUNIAKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyoto University
  •  Studies on thescale for stress induced emotional changesPrincipal Investigator

    • Principal Investigator
      SAITO Kuniaki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Kyoto University
  •  Role of indoleamine-2,3-dioxygenase in atherosclerotic carotid artery stenosis

    • Principal Investigator
      SUYAMA Kazuhiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Nagasaki University
  •  Screening and gene analysis for the protection from muscle damage by statin drugs

    • Principal Investigator
      SEISHIMA Mitsuru
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  The pathophysiologic role of indoleamine 2, 3-dioxygenase in viral infectious diseasesPrincipal Investigator

    • Principal Investigator
      SAITOU Kuniaki
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyoto University
  •  Development of device using color images to reduce stress in cancer and/or other chronic disease patients.

    • Principal Investigator
      SAITO Yumi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Fundamental nursing
    • Research Institution
      Kyoto University
  •  Study on the mechanism of rhabdomyosis induced by statins and gene analysis of patients with rhalxiomyasis

    • Principal Investigator
      TAKEMURA Masao, 和田 久泰
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  Study on analytical system for the etiology of autoimmune disease using two-dimensional nano LC/MS

    • Principal Investigator
      SEISHIMA Mitsuru
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  マウス骨髄移植技術を用いた肝不全発症機構の解明とその臨床応用に関する研究

    • Principal Investigator
      YAMADA Yasuhiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Gifu University
  •  The role of proinflammatory cytokines in the generation of myocardial ischemia/reperfusion injury

    • Principal Investigator
      WADA Hisayasu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Gifu University
  •  Proteome analysis of human macrophage cells associated with atherosclerosis

    • Principal Investigator
      FUJII Hidehiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  Study on the mechanism of atherosclerotic lesion formation using cytokine-knockout mouse

    • Principal Investigator
      SEISHIMA Mitsuru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  A mechanism of HIV-related dementia complex - relation between TNF-α and dementia -Principal Investigator

    • Principal Investigator
      SAITO Kuniaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gifu University
  •  The method for determination of serum lipid-free apolipoprotein concentration and its clinical application

    • Principal Investigator
      SEISHIMA Mitsuru
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  A study of the role of cytokines in the development of atherosclerosis using double knockout mice

    • Principal Investigator
      WADA Hisayasu, 藤井 秀比古
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Gifu University
  •  TNF-αノックアウトマウスを用いたエイズ痴呆コンプレックス発症機構に関する研究Principal Investigator

    • Principal Investigator
      斉藤 邦明
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gifu University
  •  The role of proinflammatory cytokines in the development and progression of viral myocarditis

    • Principal Investigator
      WADA Hisayasu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Gifu University
  •  Significance of soluble Fas and its related cytokines in serum of rheumatoid arthritis patients.

    • Principal Investigator
      TAKEUCHI Shoji
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  脳神経系疾患における組織修復と各種アポタンパク合成との関係Principal Investigator

    • Principal Investigator
      斉藤 邦明
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  Study on the role of Lp (a) as an acute phase reactant and on the effects on arterial endothelial and smooth muscle cells.

    • Principal Investigator
      NOMA Akio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  Basic studies of immunotherapy in relation to the serum soluble interleukin-2 receptor determination in patients with rheumatoid arthritis

    • Principal Investigator
      TAKEUCHI Shoji
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  Study on apo A-IV polymorphism in patients with hyperlipidemia.

    • Principal Investigator
      SEISHIMA Mitsuru
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University
  •  Study on structural heterogeneity of Lp(a) and its clinical significance.

    • Principal Investigator
      MAKINO Kazuhiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Gifu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 Other

All Journal Article Presentation Book Patent

  • [Book] :Tumor Necrosis factor2014

    • Author(s)
      Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K.
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Book] Tumor Necrosis factor

    • Author(s)
      Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Cohort profile: rationale and design of the Resource Center for Health Science (RECHS) project ? a study of health hazards and medical cost burden among the Japanese population2024

    • Author(s)
      Morishita Tetsuji、Takemura Masao、Hayashi Makoto、Saito Kuniaki、Yamamoto Yasuko、Tsurumi Hisashi、Matsunami Hidetoshi
    • Journal Title

      BMJ Open

      Volume: 14 Issue: 2 Pages: e077720-e077720

    • DOI

      10.1136/bmjopen-2023-077720

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Journal Article] Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass2024

    • Author(s)
      Hayashi Ryosuke、Takami Yoshiyuki、Fujigaki Hidetsugu、Amano Kentaro、Akita Kiyotoshi、Yamana Koji、Maekawa Atsuo、Saito Kuniaki、Takagi Yasushi
    • Journal Title

      The International Journal of Artificial Organs

      Volume: 47 Issue: 3 Pages: 147-154

    • DOI

      10.1177/03913988241234475

    • Data Source
      KAKENHI-PROJECT-23K27843
  • [Journal Article] Comparison of the Serial Humoral Immune Response according to the Immunosuppressive Treatment after SARS-CoV-2 mRNA Vaccination2023

    • Author(s)
      Menjo Hiroya、Hasegawa Midori、Fujigaki Hidetsugu、Ishihara Takuma、Minatoguchi Shun、Koide Shigehisa、Hayashi Hiroki、Saito Midori、Takahashi Kazuo、Ito Hiroyasu、Yuzawa Yukio、Saito Kuniaki、Tsuboi Naotake
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 23 Pages: 3445-3454

    • DOI

      10.2169/internalmedicine.1949-23

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-12-01
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-23K27843
  • [Journal Article] Dataset dependency of low-density lipoprotein-cholesterol estimation by machine learning2023

    • Author(s)
      Hidekazu Ishida、Nagasawa Hiroki、Yamamoto Yasuko、Doi Hiroki、Saito Midori、Ishihara Yuya、Fujita Takashi、Ishida Mariko、Kato Yohei、Kikuchi Ryosuke、Matsunami Hidetoshi、Takemura Masao、Ito Hiroyasu、Saito Kuniaki
    • Journal Title

      Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

      Volume: 60 Issue: 6 Pages: 396-405

    • DOI

      10.1177/00045632231180408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023

    • Author(s)
      Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
    • Journal Title

      International Journal of Hematology

      Volume: 118 Issue: 4 Pages: 462-471

    • DOI

      10.1007/s12185-023-03648-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
  • [Journal Article] Establishment of Model Mice to Evaluate Low Niacin Nutritional Status2023

    • Author(s)
      MIZUTANI Amane、SATO Miu、FUJIGAKI Hidetsugu、YAMAMOTO Yasuko、SAITO Kuniaki、HATAYAMA Sho、FUKUWATARI Tsutomu
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 69 Issue: 5 Pages: 305-313

    • DOI

      10.3177/jnsv.69.305

    • ISSN
      0301-4800, 1881-7742
    • Year and Date
      2023-10-31
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K16800, KAKENHI-PROJECT-22K11891
  • [Journal Article] Validation of the Martin method to estimate low-density lipoprotein cholesterol concentrations in Japanese populations and a modified method for laboratory information system application.2022

    • Author(s)
      Ishida H, Yamamoto Y, Saito M, Ishihara Y, Fujita T, Ishida M, Kato Y, Nohisa Y, Matsunami H, Takemura M, Hata T, Ito H, Saito K.
    • Journal Title

      Ann Clin Biochem.

      Volume: 59(5) Issue: 5 Pages: 316-323

    • DOI

      10.1177/00045632221098870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-18K02505
  • [Journal Article] The Trajectory of the COVID-19 Vaccine Antibody Titers Over Time and the Association of Mycophenolate Mofetil in Solid Organ Transplant Recipients.2022

    • Author(s)
      Sakai A, Morishita T, Suzumura K, Hanatate F, Yoshikawa T, Sasaki N, Lee S, Fujita K, Hara T, Araki H, Tagami A, Murayama M, Yamada R, Iwata A, Sobajima T,Kasahara Y, Matsuzawa Y, Takemura M, Yamamoto Y, Fujigaki H, Saito K, Tsurumi H, Matsunami H.
    • Journal Title

      Transplant Proc.

      Volume: 54(10) Issue: 10 Pages: 2638-2645

    • DOI

      10.1016/j.transproceed.2022.10.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Journal Article] CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma2022

    • Author(s)
      Okamoto Akinao、Fujigaki Hidetsugu、Iriyama Chisako、Goto Naoe、Yamamoto Hideyuki、Mihara Keichiro、Inaguma Yoko、Miura Yasuo、Furukawa Katsuya、Yamamoto Yukiya、Akatsuka Yoshiki、Kasahara Senji、Miyao Kotaro、Kajiya Ryoko、Okamoto Masataka、Saito Kuniaki、Tomita Akihiro
    • Journal Title

      Blood Advances

      Volume: 6 Issue: 11 Pages: 3230-3233

    • DOI

      10.1182/bloodadvances.2021006302

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-22K11891, KAKENHI-PROJECT-23K24297
  • [Journal Article] Automated Classification of Idiopathic Pulmonary Fibrosis in Pathological Images Using Convolutional Neural Network and Generative Adversarial Networks2022

    • Author(s)
      Teramoto Atsushi、Tsukamoto Tetsuya、Michiba Ayano、Kiriyama Yuka、Sakurai Eiko、Imaizumi Kazuyoshi、Saito Kuniaki、Fujita Hiroshi
    • Journal Title

      Diagnostics

      Volume: 12 Issue: 12 Pages: 3195-3195

    • DOI

      10.3390/diagnostics12123195

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08216, KAKENHI-PROJECT-20K08060
  • [Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021

    • Author(s)
      Mori Yuko、Mouri Akihiro、Kunisawa Kazuo、Hirakawa Mami、Kubota Hisayoshi、Kosuge Aika、Niijima Moe、Hasegawa Masaya、Kurahashi Hitomi、Murakami Reiko、Hoshi Masato、Nakano Takashi、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Behavioural Brain Research

      Volume: 405 Pages: 113191-113191

    • DOI

      10.1016/j.bbr.2021.113191

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
  • [Journal Article] Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice2021

    • Author(s)
      Wulaer Bolati、Kunisawa Kazuo、Tanabe Moeka、Yanagawa Aika、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
    • Journal Title

      Molecular Brain

      Volume: 14 Issue: 1 Pages: 43-43

    • DOI

      10.1186/s13041-021-00760-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
  • [Journal Article] Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1β expression in mice exposed to chronic social defeat stress2021

    • Author(s)
      Kosuge Aika、Kunisawa Kazuo、Arai Satoshi、Sugawara Yumika、Shinohara Katsuki、Iida Tsubasa、Wulaer Bolati、Kawai Tomoki、Fujigaki Hidetsugu、Yamamoto Yasuko、Saito Kuniaki、Nabeshima Toshitaka、Mouri Akihiro
    • Journal Title

      Brain, Behavior, and Immunity

      Volume: 96 Pages: 200-211

    • DOI

      10.1016/j.bbi.2021.05.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K16679
  • [Journal Article] Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells2021

    • Author(s)
      Yabe Kuniaki、Yamamoto Yasuko、Takemura Masao、Hara Takeshi、Tsurumi Hisashi、Serrero Ginette、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Heliyon

      Volume: 7 Issue: 1 Pages: e05849-e05849

    • DOI

      10.1016/j.heliyon.2020.e05849

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761
  • [Journal Article] Analysis of Idiopathic Interstitial Pneumonia in CT Images U ing 3D U-Net2021

    • Author(s)
      N.Takeuchi, A.Teramoto, K.Imaizumi, K.Saito, H.Fujita
    • Journal Title

      Medical Image and Information Sciences

      Volume: 38 Pages: 126-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Journal Article] Prefrontal cortex miR‐874‐3p prevents lipopolysaccharide‐induced depression‐like behavior through inhibition of indoleamine 2,3‐dioxygenase 1 expression in mice2020

    • Author(s)
      Suento Willy Jaya、Kunisawa Kazuo、Wulaer Bolati、Kosuge Aika、Iida Tsubasa、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Tanra Andi Jayalangkara、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
    • Journal Title

      Journal of Neurochemistry

      Volume: - Issue: 6 Pages: 1963-1978

    • DOI

      10.1111/jnc.15222

    • NAID

      130008001606

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K16679
  • [Journal Article] Serum metabolic profiles of the tryptophan-kynurenine pathway in the high risk subjects of major depressive disorder2020

    • Author(s)
      Sakurai Masashi、Yamamoto Yasuko、Kanayama Noriyo、Hasegawa Masaya、Mouri Akihiro、Takemura Masao、Matsunami Hidetoshi、Miyauchi Tomoya、Tokura Tatsuya、Kimura Hiroyuki、Ito Mikiko、Umemura Eri、(Boku) Aiji Sato、Nagashima Wataru、Tonoike Takashi、Kurita Kenichi、Ozaki Norio、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1961-1961

    • DOI

      10.1038/s41598-020-58806-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-19K17108, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-18K19761
  • [Journal Article] Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine2020

    • Author(s)
      Tran Hai-Quyen、Shin Eun-Joo、Saito Kuniaki、Tran The-Vinh、Phan Dieu-Hien、Sharma Naveen、Kim Dae-Won、Choi Soo Young、Jeong Ji Hoon、Jang Choon-Gon、Cheong Jae Hoon、Nabeshima Toshitaka、Kim Hyoung-Chun
    • Journal Title

      Food and Chemical Toxicology

      Volume: 136 Pages: 110986-110986

    • DOI

      10.1016/j.fct.2019.110986

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252
  • [Journal Article] Lithium attenuates d‐amphetamine‐induced hyperlocomotor activity in mice via inhibition of interaction between cyclooxygenase‐2 and indoleamine‐2,3‐dioxygenase2020

    • Author(s)
      Phan Dieu‐Hien、Shin Eun‐Joo、Jeong Ji Hoon、Tran Hai‐Quyen、Sharma Naveen、Nguyen Bao Trong、Jung Tae Woo、Nah Seung‐Yeol、Saito Kuniaki、Nabeshima Toshitaka、Kim Hyoung‐Chun
    • Journal Title

      Clinical and Experimental Pharmacology and Physiology

      Volume: 47 Issue: 5 Pages: 790-797

    • DOI

      10.1111/1440-1681.13243

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252
  • [Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2020

    • Author(s)
      Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
    • Journal Title

      World J Gastroenterol.

      Volume: 26 Issue: 9 Pages: 918-932

    • DOI

      10.3748/wjg.v26.i9.918

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
  • [Journal Article] Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.2020

    • Author(s)
      Hoshi M, Osawa Y, Nakamoto K, Morita N, Yamamoto Y, Ando T, Tashita C, Nabeshima T, Saito K.
    • Journal Title

      Toxicology

      Volume: 438 Pages: 152458-152458

    • DOI

      10.1016/j.tox.2020.152458

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873, KAKENHI-PROJECT-17H04252
  • [Journal Article] Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus2020

    • Author(s)
      Wulaer Bolati、Kunisawa Kazuo、Hada Kazuhiro、Jaya Suento Willy、Kubota Hisayoshi、Iida Tsubasa、Kosuge Aika、Nagai Taku、Yamada Kiyofumi、Nitta Atsumi、Yamamoto Yasuko、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
    • Journal Title

      Journal of Neurochemistry

      Volume: 157 Issue: 3 Pages: 642-655

    • DOI

      10.1111/jnc.15022

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K16679
  • [Journal Article] Prefrontal cortex, dorsomedial striatum, and dentate gyrus are necessary in the object-based attention test in mice2020

    • Author(s)
      Wulaer Bolati、Kunisawa Kazuo、Kubota Hisayoshi、Suento Willy Jaya、Saito Kuniaki、Mouri Akihiro、Nabeshima Toshitaka
    • Journal Title

      Molecular Brain

      Volume: 13 Issue: 1 Pages: 391-391

    • DOI

      10.1186/s13041-020-00711-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K16679
  • [Journal Article] Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms2019

    • Author(s)
      Teshigawara Tomoaki、Mouri Akihiro、Kubo Hisako、Nakamura Yukako、Shiino Tomoko、Okada Takashi、Morikawa Mako、Nabeshima Toshitaka、Ozaki Norio、Yamamoto Yasuko、Saito Kuniaki
    • Journal Title

      Journal of Affective Disorders

      Volume: 255 Pages: 168-176

    • DOI

      10.1016/j.jad.2019.05.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K16375, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-16K10248
  • [Journal Article] 5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox2019

    • Author(s)
      Tran Hai-Quyen、Shin Eun-Joo、Hoai Nguyen Bao-Chau、Phan Dieu-Hien、Kang Min-Ji、Jang Choon-Gon、Jeong Ji Hoon、Nah Seung-Yeol、Mouri Akihiro、Saito Kuniaki、Nabeshima Toshitaka、Kim Hyoung-Chun
    • Journal Title

      Food and Chemical Toxicology

      Volume: 123 Pages: 125-141

    • DOI

      10.1016/j.fct.2018.10.049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252
  • [Journal Article] Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region2019

    • Author(s)
      Tomoya Miyauchia, Tatsuya Tokuraa,*, Hiroyuki Kimuraa, Mikiko Itob, Eri Umemurab, Aiji Sato (boku)c, Wataru Nagashimad, Takashi Tonoikee, Yasuko Yamamotof, Kuniaki Saitof,g, Kenichi Kuritab, Norio Ozaki
    • Journal Title

      Human Psychopharmacology: Clinical & Experimental

      Volume: 34 Issue: 4

    • DOI

      10.1002/hup.2698

    • NAID

      120006767392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K17108
  • [Journal Article] Decline of Plasma Concentrations of Interleukin-18 in Severely Malnourished Patients with Anorexia Nervosa: Exploratory Analysis.2019

    • Author(s)
      Tanaka S, Oya-Ito T, Murakami Y, Saito K, Furuta S, Yu Y, Imaeda M, Kunimoto S, Ozaki N.
    • Journal Title

      Nutrients.

      Volume: 11(3) Issue: 3 Pages: 1-6

    • DOI

      10.3390/nu11030540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K00851, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-16K10211
  • [Journal Article] Generalized Pustular Psoriasis from heterozygous IL36RN mutation developed after liver surgery.2019

    • Author(s)
      Fukushima H, Iwata Y, Numata, Saito K, Watanabe S, Kobayashi T, Sugiura K.
    • Journal Title

      J Deramtol

      Volume: - Issue: 8

    • DOI

      10.1111/1346-8138.14828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-15H04886
  • [Journal Article] Indoleamine 2,3‐dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma2019

    • Author(s)
      Yamasuge Wakana、Yamamoto Yasuko、Fujigaki Hidetsugu、Hoshi Masato、Nakamoto Kentaro、Kunisawa Kazuo、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 10 Pages: 3061-3067

    • DOI

      10.1111/cas.14179

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-18K15377
  • [Journal Article] Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression2019

    • Author(s)
      Lu Qiaohui、Mouri Akihiro、Yang Yang、Kunisawa Kazuo、Teshigawara Tomoaki、Hirakawa Mami、Mori Yuko、Yamamoto Yasuko、Libo Zou、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Behavioural Brain Research

      Volume: 372 Pages: 112053-112053

    • DOI

      10.1016/j.bbr.2019.112053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-18K15377
  • [Journal Article] Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia2019

    • Author(s)
      Fujigaki Hidetsugu、Mouri Akihiro、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Neurochemistry International

      Volume: 125 Pages: 1-6

    • DOI

      10.1016/j.neuint.2019.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969
  • [Journal Article] Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker.2019

    • Author(s)
      Murakami Y, Imamura Y, Saito K, Sakai D
    • Journal Title

      Scientific reports

      Volume: 10(1) Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41598-020-60585-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-19K06680, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-20K21587, KAKENHI-PROJECT-17H04364
  • [Journal Article] Alteration of specific cytokine expression patterns in patients with breast cancer.2019

    • Author(s)
      Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M.
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 2924-2924

    • DOI

      10.1038/s41598-019-39476-9

    • NAID

      120006578938

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07014, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222
  • [Journal Article] Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues2019

    • Author(s)
      Yoshida Yukihiro、Fujigaki Hidetsugu、Kato Koichi、Yamazaki Kyoka、Fujigaki Suwako、Kunisawa Kazuo、Yamamoto Yasuko、Mouri Akihiro、Oda Akifumi、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 10243-10243

    • DOI

      10.1038/s41598-019-46666-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K08257, KAKENHI-PROJECT-18K15377
  • [Journal Article] Fatigue-induced decline in low-frequency common input to bilateral and unilateral plantar flexors during quiet standing2018

    • Author(s)
      Watanabe Tatsunori、Saito Kotaro、Ishida Kazuto、Tanabe Shigeo、Nojima Ippei
    • Journal Title

      Neuroscience Letters

      Volume: 686 Pages: 193-197

    • DOI

      10.1016/j.neulet.2018.09.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19761, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05880, KAKENHI-PROJECT-15H03044, KAKENHI-PROJECT-17H04748, KAKENHI-PROJECT-17J00700, KAKENHI-PROJECT-15KK0117
  • [Journal Article] Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.2018

    • Author(s)
      A Sobue, N Ito, T Nagai, W Shan, K Hada, Nakajima A, Y Murakami, A Mouri, Y Yamamoto, T Nabeshima, K Saito, K Yamada
    • Journal Title

      Glia

      Volume: 66 Issue: 5 Pages: 1034-52

    • DOI

      10.1002/glia.23299

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-15H03086
  • [Journal Article] Recurrent Cutaneous Rosai-Dorfman Disease: A case Report.2018

    • Author(s)
      Yoshimoto N, Iwata Y, Numata S, Saito K, Iwata T, Arima M, Shima H, Tahara S, Kuroda M, Sugiura K.
    • Journal Title

      Eur J Dermatol

      Volume: 28 Issue: 4 Pages: 562-563

    • DOI

      10.1684/ejd.2018.3348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-15H04886
  • [Journal Article] Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis2018

    • Author(s)
      Kimura Akio、Takemura Masao、Serrero Ginette、Yoshikura Nobuaki、Hayashi Yuichi、Saito Kuniaki、Inuzuka Takashi
    • Journal Title

      Journal of Neuro-Oncology

      Volume: 137 Issue: 3 Pages: 455-462

    • DOI

      10.1007/s11060-017-2742-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15445, KAKENHI-PROJECT-15H03086
  • [Journal Article] Excess maternal fructose consumption impairs hippocampal function in offspring via epigenetic modification of BDNF promoter.2018

    • Author(s)
      Yamazaki M, Yamada H, Munetsuna E, Ishikawa H, Mizuno G, Mukuda T, Mouri A, Nabeshima T, Saito K, Suzuki K, Hashimoto S, Ohashi K.
    • Journal Title

      FASEB J.

      Volume: 32 Issue: 5 Pages: 2549-2562

    • DOI

      10.1096/fj.201700783rr

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-18K17987, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17J10969, KAKENHI-PROJECT-15H03086
  • [Journal Article] PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis.2018

    • Author(s)
      Tran HQ, Lee Y, Shin EJ, Jang CG, Jeong JH, Mouri A, Saito K, Nabeshima T, Kim HC.
    • Journal Title

      Mol Neurobiol.

      Volume: 印刷中 Issue: 10 Pages: 7802-7821

    • DOI

      10.1007/s12035-018-0938-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252
  • [Journal Article] IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings2018

    • Author(s)
      Mai Huynh Nhu、Chung Yoon Hee、Shin Eun-Joo、Sharma Naveen、Jeong Ji Hoon、Jang Choon-Gon、Saito Kuniaki、Nabeshima Toshitaka、Reglodi Dora、Kim Hyoung-Chun
    • Journal Title

      Food and Chemical Toxicology

      Volume: 116 Pages: 249-263

    • DOI

      10.1016/j.fct.2018.04.031

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Journal Article] Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling2018

    • Author(s)
      Yamamoto Yasuko、Yamasuge Wakana、Imai Shinjiro、Kunisawa Kazuo、Hoshi Masato、Fujigaki Hidetsugu、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 15917-15917

    • DOI

      10.1038/s41598-018-34166-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K15377
  • [Journal Article] Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer's disease2017

    • Author(s)
      .Kimura A, Takemura M, Saito K, Yoshikura N, Hayashi Y, Inuzuka T.
    • Journal Title

      J NEUROL NEUROSUR PSYCHIATRY

      Volume: 88 Issue: 2 Pages: 126-131

    • DOI

      10.1136/jnnp-2016-313476

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
  • [Journal Article] Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice.2017

    • Author(s)
      Kubo H, Hoshi M, Matsumoto T, Irie M, Oura S, Tsutsumi H, Hata Y, Yamamoto Y, Saito K
    • Journal Title

      Lipids Health Dis.

      Volume: 16(1) Issue: 1 Pages: 106-106

    • DOI

      10.1186/s12944-017-0501-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-15H03086
  • [Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017

    • Author(s)
      Ohta Y , Kubo H , Yashiro K , Ohashi K , Tsuzuki Y , Wada N , Yamamoto Y , Saito, K
    • Journal Title

      JOURNAL OF PHYSIOLOGICAL SCIENCES

      Volume: 67 Pages: 361-372

    • NAID

      40021176369

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Journal Article] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice2017

    • Author(s)
      Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.
    • Journal Title

      IMMUNOLOGY LETTERS

      Volume: 181 Pages: 94-100

    • DOI

      10.1016/j.imlet.2016.11.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860376, KAKENHI-PROJECT-16K10195
  • [Journal Article] Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas.2017

    • Author(s)
      Yamamoto Y, Goto N, Takemura M, Yamasuge W, Yabe K, Takami T, Miyazaki T, Takeuchi T, Shiraki M, Shimizu M, Adachi S, Saito K, Shibata Y, Nakamura N, Hara T, Serrero G, Saito K, Tsurumi H.
    • Journal Title

      Clin Chim Acta

      Volume: 473 Pages: 139-146

    • DOI

      10.1016/j.cca.2017.07.024

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09920, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
  • [Journal Article] Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder.2017

    • Author(s)
      Kimura A, Takemura M, Saito K, Serrero G, Yoshikura N, Hayashi Y, Inuzuka T.
    • Journal Title

      JOURNAL OF NEUROIMMUNOLOGY

      Volume: 305 Pages: 175-181

    • DOI

      10.1016/j.jneuroim.2017.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
  • [Journal Article] Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions2017

    • Author(s)
      Tashiro T , Murakami Y , Mouri A , Imamura Y, Nabeshima T, Yamamoto, Y , Saito, K
    • Journal Title

      BEHAVIOURAL BRAIN RESEARCH

      Volume: 317 Pages: 279-285

    • DOI

      10.1016/j.bbr.2016.09.050

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H04364
  • [Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017

    • Author(s)
      Ohta, Y ; Kubo, H ; Yashiro, K ; Ohashi, K ; Tsuzuki, Y ; Wada, N ; Yamamoto, Y ; Saito, K
    • Journal Title

      JOURNAL OF PHYSIOLOGICAL SCIENCES 4.巻 67 5.発行年 2017

      Volume: 4 Pages: 361-372

    • NAID

      40021176369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460675
  • [Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues.2017

    • Author(s)
      Ohta Y, Kubo H, Yashiro K, Ohashi K, Tsuzuki Y, Wada N, Yamamoto Y, Saito K.
    • Journal Title

      J Physiol Sci.

      Volume: 67(3) Issue: 3 Pages: 361-372

    • DOI

      10.1007/s12576-016-0467-y

    • NAID

      40021176369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
  • [Journal Article] Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1.2016

    • Author(s)
      Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K.
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 6 Issue: 1 Pages: 29920-29920

    • DOI

      10.1038/srep29920

    • NAID

      120006323748

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-15H04100, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948
  • [Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences.2016

    • Author(s)
      Fujigaki H, Yamamoto Y, Saito K
    • Journal Title

      Neuropharmacology.

      Volume: 印刷中 Pages: 264-274

    • DOI

      10.1016/j.neuropharm.2016.01.011

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26860379, KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675
  • [Journal Article] Prognostic value of the combination of serum l-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia.2016

    • Author(s)
      Hara T, Matsumoto T, Shibata Y, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Nannya Y, Shimizu M, Ito H, Saito K, Tsurumi H.
    • Journal Title

      Leuk Lymphoma.

      Volume: 13 Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Journal Article] Serum concentrations of l-kynurenine predict clinical outcomes of patients with peripheral T-cell lymphoma, not otherwise specified.2016

    • Author(s)
      Shibata Y, Hara T, Matsumoto T, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Goto N, Nannya Y, Ito H, Kito Y, Miyazaki T, Takeuchi T, Saito K, Seishima M, Takami T, Moriwaki H, Shimizu M, Tsurumi H.
    • Journal Title

      Hematological Oncology

      Volume: - Issue: 4 Pages: 637-644

    • DOI

      10.1002/hon.2318

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06247, KAKENHI-PROJECT-16K19310, KAKENHI-PROJECT-15H03086
  • [Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacology.2016

    • Author(s)
      Fujigaki H, Yamamoto Y, Saito K.
    • Journal Title

      j.neuropharm.

      Volume: S0028-3908(16) Pages: 30011-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Journal Article] Effects of various phytochemicals on indoleamine 2, 3-dioxygenase 1 activity : galanal is a novel, competitive inhibitor of the enzyme2014

    • Author(s)
      Yamamoto R, Yamamoto Y, Imai S, Fukutomi R, Ozawa Y, Abe M, Matuo Y, Saito K
    • Journal Title

      PLoS One

      Volume: 12;9(2) Issue: 2 Pages: e88789-e88789

    • DOI

      10.1371/journal.pone.0088789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis2014

    • Author(s)
      Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A
    • Journal Title

      Neurosci Lett

      Volume: 3564 Pages: 120-5

    • DOI

      10.1016/j.neulet.2014.01.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-26860376
  • [Journal Article] Induction of HBsAg-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity2014

    • Author(s)
      Ito H, Ando T, Ando K, Ishikawa T, Saito K, Moriwaki H, Seishima M
    • Journal Title

      Immunology

      Volume: 印刷中 Issue: 4 Pages: 614-623

    • DOI

      10.1111/imm.12274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361
  • [Journal Article] Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014

    • Author(s)
      Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
    • Journal Title

      Biochim Biophys Acta

      Volume: S0925-4439(14) Pages: 102-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270
  • [Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis.2014

    • Author(s)
      Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A.
    • Journal Title

      Neurosci Lett

      Volume: 564 Pages: 120-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270
  • [Journal Article] Kynurenine production mediated by indoleamine 2, 3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014

    • Author(s)
      Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
    • Journal Title

      Biochim Biophys Acta

      Volume: 1842(9) Issue: 9 Pages: 1464-71

    • DOI

      10.1016/j.bbadis.2014.04.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361, KAKENHI-PROJECT-26860376
  • [Journal Article] Effects of indoleamine 2, 3-dioxygenase deficiency on high-fat diet-induced hepatic inflammation2013

    • Author(s)
      Nagano J, Shimizu M, Hara T, Shirakami Y, Kochi T, Nakamura N, Ohtaki H, Ito H, Tanaka T, Tsurumi H, Saito K, Seishima M, Moriwaki H
    • Journal Title

      PLoS One

      Volume: 9;8(9) Issue: 9 Pages: e73404-e73404

    • DOI

      10.1371/journal.pone.0073404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-25460987, KAKENHI-PROJECT-25460988
  • [Journal Article] [Indoleamine 2,3-dioxygenase 1 modulates the immuneresponse; the new therapeutic targets of this drug].2013

    • Author(s)
      Yamamoto Y, Murakami Y, Hoshi M, Saito K.
    • Journal Title

      Nihon Yakurigaku Zasshi

      Volume: 142(2) Pages: 85-8

    • NAID

      10031190742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270
  • [Journal Article] Remarkable role of indoleamine 2, 3-dioxygenase and tryptophan metabolites in infectious diseases : potential role in macrophage-mediated inflammatory diseases2013

    • Author(s)
      Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K
    • Journal Title

      Mediators Inflamm

      Volume: 2013 Pages: 391984-391984

    • DOI

      10.1155/2013/391984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790621, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-24890270
  • [Journal Article] Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.2013

    • Author(s)
      Kawasoe M, Yamamoto Y, Okawa K, Funato T, Takeda M, Hara T, Tsurumi H, Moriwaki H, Arioka Y, Takemura M, Matsunami H, Markey SP, Saito K.
    • Journal Title

      Exp Hematol.

      Volume: 41(7) Issue: 7 Pages: 597-603

    • DOI

      10.1016/j.exphem.2013.03.004

    • NAID

      120005302084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] IDO1 plays an immunosuppressive role in 2, 4, 6-trinitrobenzene sulfate-induced colitis in mice2013

    • Author(s)
      Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A
    • Journal Title

      J Immunol

      Volume: 15;191(6) Issue: 6 Pages: 3057-64

    • DOI

      10.4049/jimmunol.1203306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24790381, KAKENHI-PROJECT-24890270
  • [Journal Article] IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2013

    • Author(s)
      Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A.
    • Journal Title

      J Immunol

      Volume: 191(6) Pages: 3057-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270
  • [Journal Article] Species and cell types difference in tryptophan metabolism2013

    • Author(s)
      Murakami Y, Saito K
    • Journal Title

      Int J Tryptophan Res

      Volume: 21;6 Pages: 47-54

    • DOI

      10.4137/ijtr.s11558

    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Pre-administration of L-tryptophan improved ADR-induced early renal failure in mice2012

    • Author(s)
      Arioka Y
    • Journal Title

      Life Sci

      Volume: 59 Issue: 3-4 Pages: 100-106

    • DOI

      10.1016/j.lfs.2012.06.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
  • [Journal Article] Posttranslational modification of indoleamine 2, 3-dioxygenase2012

    • Author(s)
      Fujigaki H, Seishima M, Saito K
    • Journal Title

      Anal Bioanal Chem

      Volume: 403(7) Issue: 7 Pages: 1777-82

    • DOI

      10.1007/s00216-012-5946-2

    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] -Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells2012

    • Author(s)
      Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
    • Journal Title

      Oncol Lett

      Volume: 4(3) Pages: 546-550

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673646/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890270
  • [Journal Article] 遺伝子検査に有用なインターネット活用2012

    • Author(s)
      齋藤邦明
    • Journal Title

      Medical Technology

      Volume: 40 Pages: 1580-1580

    • Data Source
      KAKENHI-PROJECT-23650417
  • [Journal Article] High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice2012

    • Author(s)
      Ohtaki H
    • Journal Title

      Sci Rep.

      Volume: 2 Issue: 1 Pages: 367-375

    • DOI

      10.1038/srep00367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
  • [Journal Article] 健康管理におけるオミックス解析の意義2012

    • Author(s)
      村上由希、松尾雄志、齋藤邦明
    • Journal Title

      医療と検査機器試薬

      Volume: 35 Pages: 331-334

    • Data Source
      KAKENHI-PROJECT-23650417
  • [Journal Article] Epigallocatechin gallate inhibits the expression of indoleamine 2, 3-dioxygenase in human colorectal cancer cells2012

    • Author(s)
      Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
    • Journal Title

      Oncol Lett

      Volume: 4(3) Pages: 546-550

    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Posttranslational modification of indoleamine 2,3-dioxygenase2012

    • Author(s)
      Fujigaki H, Seishima M, Saito K
    • Journal Title

      Anal Bioanal Chem

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2, 3-dioxygenase2012

    • Author(s)
      Ogawa K, Hara T, Shimizu M, Ninomiya S, Nagano J, Sakai H, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Tanaka T, Moriwaki H
    • Journal Title

      Cancer Sci

      Volume: 103 Issue: 5 Pages: 951-958

    • DOI

      10.1111/j.1349-7006.2012.02237.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590838, KAKENHI-PROJECT-24890270
  • [Journal Article] L-tryptophan-kynurenine pathway metabolites regulate type 1 IFNs of acute viral myocarditis in mice2012

    • Author(s)
      Hoshi M
    • Journal Title

      J Immunol

      Volume: 188 Issue: 8 Pages: 3980-3987

    • DOI

      10.4049/jimmunol.1100997

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
  • [Journal Article] L-Tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice2012

    • Author(s)
      Hoshi M, Yamamoto Y, Saito K, 他4名
    • Journal Title

      J Immunol

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Journal Article] Studies on tissue and cellular distribution of indoleamine 2, 3-dioxygenase 2 : the absence of IDO1 upregulates IDO2 expression in the epididymis2012

    • Author(s)
      Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K
    • Journal Title

      J Histochem Cytochem

      Volume: 60(11) Issue: 11 Pages: 854-60

    • DOI

      10.1369/0022155412458926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
  • [Journal Article] Inhibition of increased indoleamine 2, 3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection2012

    • Author(s)
      Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, Matsunami H, Funato T, Seishima M, Saito K
    • Journal Title

      Cytokine

      Volume: 59(2) Issue: 2 Pages: 245-51

    • DOI

      10.1016/j.cyto.2012.04.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
  • [Journal Article] 遺伝子検査に有用なインターネット活用2012

    • Author(s)
      斉藤邦明
    • Journal Title

      Medical Technology

      Volume: 40 Pages: 1580-1580

    • Data Source
      KAKENHI-PROJECT-23650417
  • [Journal Article] Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011

    • Author(s)
      Ninomiya S, Hara T, Saito K, 他13名
    • Journal Title

      Ann Hematol

      Volume: 90(4) Pages: 409-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011

    • Author(s)
      Ninomiya S, Hara T, Tsurumi H, Hoshi M, Kanemura N, Goto N, Kasahara S, Shimizu M, Ito H, Saito K, Hirose Y, Yamada T, Takahashi T, Seishima M, Takami T, Moriwaki H.
    • Journal Title

      Ann Hematol.

      Volume: 90(4) Issue: 4 Pages: 409-16

    • DOI

      10.1007/s00277-010-1093-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model2011

    • Author(s)
      Ito H, Hoshi M, Saito K, 他
    • Journal Title

      J Immunol

      Volume: 185(8) Pages: 4554-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin2011

    • Author(s)
      Osawa Y, Kanamori H, Seki E, Hoshi M, Ohtaki H, Yasuda Y, Ito H, Suetsugu A, Nagaki M, Moriwaki H, Saito K, Seishima M
    • Journal Title

      Journal of Biological Chemistry

      Volume: 286 Issue: 40 Pages: 34800-34808

    • DOI

      10.1074/jbc.m111.235473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J06850, KAKENHI-PROJECT-20390167, KAKENHI-PROJECT-21390179
  • [Journal Article] バイオリソース有効活用:RECHSにおける仕組みづくりの重要性2011

    • Author(s)
      松尾雄志、松波英寿、竹村正男、齋藤邦明
    • Journal Title

      臨床病理

      Volume: 59 Pages: 1124-1130

    • Data Source
      KAKENHI-PROJECT-23650417
  • [Journal Article] Ability of IDO to attenuate liver in juryin alpha-galactosylceramide-in duced hepatitis model2010

    • Author(s)
      Ito H, Hoshi M, Ohtaki H, Taguchi A, AndoK, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M.
    • Journal Title

      J Immunol.

      Volume: 185(8) Issue: 8 Pages: 4554-60

    • DOI

      10.4049/jimmunol.0904173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Serum concentration of L-kynureninepredicts the clinical outcome of patientswith diffuse large B-cell lymphoma treated with R-CHOP2010

    • Author(s)
      Yoshikawa T, Hara T, Tsurumi H, Goto N, Hoshi M, Kitagawa J, Kanemura N, Kasahara S, Ito H, Takemura M, Saito K, Seishima M, Takami T, Moriwaki H.
    • Journal Title

      Eur J Haematol.

      Volume: 84(4) Issue: 4 Pages: 304-309

    • DOI

      10.1111/j.1600-0609.2009.01393.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010

    • Author(s)
      石山瑠理、齋藤ゆみ
    • Journal Title

      健康科学(京都大学医学部保健学科紀要) 6巻

      Pages: 1-7

    • NAID

      120002056250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010

    • Author(s)
      Hoshi M, Saito K, Hara A, Taguchi A, OhtakiH, Tanaka R, Fujigaki H, Osawa Y, TakemuraM, Matsunami H, Ito H, Seishima M.
    • Journal Title

      J Immunol.

      Volume: 185(6) Issue: 6 Pages: 3305-12

    • DOI

      10.4049/jimmunol.0901150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010

    • Author(s)
      石山瑠理, 齋藤ゆみ
    • Journal Title

      健康科学 (京都大学医学部保健学科紀要) 6

      Pages: 1-7

    • NAID

      120002056250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] 好みの単色彩光による感情刺激効果2010

    • Author(s)
      齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
    • Journal Title

      日本補完代替医療学会

      Volume: 7 Pages: 103-111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] 好みの単色彩光による感情刺激効果2010

    • Author(s)
      齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
    • Journal Title

      日本補完代替医療学会 7巻

      Pages: 103-111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010

    • Author(s)
      Hoshi M, Saito K, 他10名
    • Journal Title

      J Immunol

      Volume: 185(6) Pages: 3305-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Changes in serum tryptophan catabolism as an indicator of disease activity in adult T-cell leukemia/lymphoma2009

    • Author(s)
      Hoshi M, Ito H, Fujigaki H, Takemura M, Takahashi T, Tomita E, Ohyama M, Tanaka R, Ohtaki H, Saito K, Seishima M.
    • Journal Title

      LeukLymphoma.

      Volume: 50(8) Issue: 8 Pages: 1372-1374

    • DOI

      10.1080/10428190903045393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following2009

    • Author(s)
      Hoshi M, Saito K, Murakami, 他7名
    • Journal Title

      Neurosci Res. 63

      Pages: 194-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Statin-induced Ca2+release wasincreased in B lymphocytes in patients who showed elevated serum creatine kinase during statin treatment.2009

    • Author(s)
      Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M,Seishima M.
    • Journal Title

      J Atheroscler Thromb

      Volume: 16 Pages: 870-7

    • URL

      https://www.jstage.jst.go.jp/browse/jat

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390179
  • [Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse2009

    • Author(s)
      Hoshi M, Saito K, Murakami Y, Taguchi A, Fujigaki H, Tanaka R, Takemura M, Ito H, Hara A, Seishima M.
    • Journal Title

      Neurosci Res.

      Volume: 63(3) Issue: 3 Pages: 194-198

    • DOI

      10.1016/j.neures.2008.12.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] Interaction between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Valpha14 NKT cells2009

    • Author(s)
      Ohtaki H, Ito H, Ando K, Ishikawa T, HoshiM, Tanaka R, Osawa Y, Yokochi T, MoriwakiH, Saito K, Seishima M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 389(2) Issue: 2 Pages: 229-34

    • DOI

      10.1016/j.bbrc.2009.08.120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008

    • Author(s)
      齋藤ゆみ, 笹山哲
    • Journal Title

      日本補完代替医療学会誌 5

      Pages: 225-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] Localization and spatiotemporal expression of IDO following transient forebrain ischemia in gerbils.2008

    • Author(s)
      Taguchi A, Hara A, Saito K, 他4名
    • Journal Title

      Brain Res. 1217

      Pages: 78-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008

    • Author(s)
      齋藤ゆみ、笹山哲、菅佐和子、池本正生
    • Journal Title

      日本補完代替医療学会誌 5巻

      Pages: 225-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390541
  • [Journal Article] Nitration and inactivation of IDO by peroxynitrite.2006

    • Author(s)
      Fujigaki H, Saito K, Lin F, Fujigaki S, Takahashi K, Martin BM, Chen CY, Masuda J, Kowalak J, Takikawa O, Seishima M, Markey SP.
    • Journal Title

      The Journal of Immunology 176(1)

      Pages: 372-379

    • Data Source
      KAKENHI-PROJECT-17390161
  • [Journal Article] The signal transducer and activator of trenscription 1α and interferon regulatory factor 1are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide : involvement of p38 mitogen-activated protein kinase and nuclear factor-κ B pathways, and synergistic effect of several proinflammatory cytokines.2006

    • Author(s)
      Fujigaki H, Saito K, Fujigaki S, Takemura M, Sudo K, lshiguro H, Seishima M.
    • Journal Title

      The Journal of Biochemistry 139(4)

      Pages: 655-662

    • Data Source
      KAKENHI-PROJECT-18590525
  • [Journal Article] Nitration and inactivation of indoeamine 2,3-dioxygenase by peroxynitrite2006

    • Author(s)
      Fujigaki H, Saito K, Seishima M他
    • Journal Title

      J.Immunol 176

      Pages: 372-379

    • Data Source
      KAKENHI-PROJECT-17390161
  • [Journal Article] The signal transducer and activity of transcription 1a and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide2006

    • Author(s)
      Fujigaki H, Saito K, Seishima M他
    • Journal Title

      J.Biochem. (In Press)

    • Data Source
      KAKENHI-PROJECT-17390161
  • [Patent] 関節リューマチ患者における生物学的製剤の有効性の予測方法2013

    • Inventor(s)
      斉藤邦明, 坪井彩, 山本康子
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Number
      2013-127092
    • Filing Date
      2013-06-18
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Patent] 免疫抵抗性疾患耐性をもった動物の育種方法2010

    • Inventor(s)
      斉藤邦明、市村直也
    • Industrial Property Rights Holder
      斉藤邦明、成宮明
    • Filing Date
      2010
    • Data Source
      KAKENHI-PROJECT-20390167
  • [Presentation] 暦年的なデータベースを用いた機械学習による高血圧予備群の予測2023

    • Author(s)
      水谷宗慈、山本康子、竹村正男、藤垣英嗣、齋藤邦明
    • Organizer
      第63回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Presentation] 生体分子間相互作用解析装置を用いた血清中抗新型コロナウイルス抗体とウイルスの結合親和性の評価2023

    • Author(s)
      高尾明日香、藤垣英嗣、杉浦彩香、小森隆弘、斉藤憲佑、竹村正男、齋藤邦明
    • Organizer
      日本医療検査科学会第55回大会
    • Data Source
      KAKENHI-PROJECT-23K27843
  • [Presentation] Improved Classification Scheme of Idiopathic Interstitial Pneumonias in Histopathological Images Using Generative Adversarial Networks,2023

    • Author(s)
      Teramoto Atsushi、Tsukamoto Tetsuya、Michiba Ayano、Kiriyama Yuka、Sakurai Eiko、Imaizumi Kazuyoshi、Saito Kuniaki、Fujita Hiroshi
    • Organizer
      IFMIA 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 質量分析計を用いた新型コロナウイルス感染症患者血清中のトリプトファン代謝産物一斉定量解析2023

    • Author(s)
      藤垣英嗣、高尾明日香、杉浦彩香、藤垣朱和子、生野彰宏、山本康子、齋藤邦明
    • Organizer
      第42回日本トリプトファン研究会学術集会
    • Data Source
      KAKENHI-PROJECT-23K27843
  • [Presentation] ワクチン接種による免疫獲得者とハイブリッド免疫獲得者の血清中抗SARS-C0V-2抗体価の推移の違い2023

    • Author(s)
      杉浦彩香、藤垣英嗣、高尾明日香、加藤詩緒、水谷宗慈、山本康子、竹村正男、齋藤邦明
    • Organizer
      日本医療検査科学会第55回大会
    • Data Source
      KAKENHI-PROJECT-23K27843
  • [Presentation] ホールスライド画像を用いた特発性間質性肺炎の病型自動分類2022

    • Author(s)
      寺本篤司, 道塲彩乃, 桐山諭和, 櫻井映子, 塚本徹哉, 今泉和良, 齋藤邦明, 藤田広志
    • Organizer
      第41回 日本医用画像工学会大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 胎生期バルプロ酸曝露は5-HT1A受容体シグナルの低下を介して前頭前皮質でのNMDA受容体シグナルの亢進とASD様行動を惹起する2022

    • Author(s)
      倉橋 仁美、毛利 彰宏、國澤 和生、田中 謙二、窪田 悠力、長谷川 眞也、小菅 愛加、齋藤 邦明鍋島 俊隆
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 生化学自動分析装置JCA-BM9130を用いた新型コロナウイルス抗体検査試薬「SARS-CoV-2 UTAB FS」の有用性の検討2022

    • Author(s)
      藤垣 英嗣, 竹村 正男, 齊藤 翠, 藤田 孝, 山本 康子, 齋藤 邦明
    • Organizer
      医学と薬学
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Presentation] 敵対的生成ネットワークと畳み込みニューラルネットワークを用いた病理画像における特発性間質性肺炎の自動鑑別2022

    • Author(s)
      寺本篤司, 道塲彩乃, 桐山諭和, 櫻井映子, 塚本徹哉, 今泉和良, 齋藤邦明, 藤田広志
    • Organizer
      医用画像情報学会 令和4年度秋季大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 思春期でのアルコール暴飲は灰白質の髄鞘異常を介して成人期における行動異常を誘発する2022

    • Author(s)
      菅原 侑実香、國澤 和生、吉富 航平、今 勇貴、齋藤 邦明、毛利 彰宏、鍋島 俊隆
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] グリア細胞におけるトリプトファン代謝変容によるうつ病の病態形成2022

    • Author(s)
      毛利 彰宏、國澤 和生、齋藤 邦明、鍋島 俊隆
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Shati/Nat8l欠損は腹側被蓋野-前頭前皮質間におけるドパミン作動性神経系の投射を障害することで注意機能障害を誘発する2022

    • Author(s)
      國澤 和生、Wulaer Bolati、小菅 愛加、田辺 萌夏、齋藤 邦明、鍋島 俊隆、毛利 彰宏
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 慢性予測不能軽度ストレスによるうつ様行動および視床下部-下垂体-副腎系の調節不全はキヌレニン-3-モノオキシゲナーゼ発現低下によるキヌレン酸の増加が関与している2022

    • Author(s)
      長谷川 眞也、毛利 彰宏、國澤 和生、窪田 悠力、倉橋 仁美、小菅 愛加、山本 康子、齋藤 邦明、鍋島 俊隆
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] ADVIA Centaur XPTによるIL-6測定の基礎的検討と臨床的意義 関節リウマチ患者を対象に検討2022

    • Author(s)
      石田 秀和, 竹村 正男, 佐藤 正夫, 山本 康子, 藤垣 英嗣, 佐々木 智裕, 森本 剛史, 酒井 昭嘉, 伊藤 弘康, 斉藤 邦明
    • Organizer
      医療検査と自動化
    • Data Source
      KAKENHI-PROJECT-22K11891
  • [Presentation] ミロイド β注入による認知機能低下におけるトリプトファン代謝を介した興奮-抑制バランスの関与(優秀賞受賞)2021

    • Author(s)
      倉橋仁美、毛利彰宏、國澤和生、窪田悠力、長谷川眞也、山本康子、齋藤邦明、鍋島俊隆ア
    • Organizer
      第139回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Weakly Supervised Classification Scheme of Idiopathic Interstitial Pneumonia Using Attention-based Deep Multiple Instance Learning2021

    • Author(s)
      N.Takeuchi, A.Teramoto, K.Imaizumi, K.Saito, H.Fujita
    • Organizer
      第77回日本放射線技術学会総会学術大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 慢性社会的敗北ストレスにより誘発されるうつ様行動において小脳血液‐脳関門の破綻が関与する2021

    • Author(s)
      小菅愛加、國澤和生、手塚裕之、星 雅人、森田那奈架、河合智貴、山本康子、齋藤邦明、鍋島俊隆、毛利彰宏
    • Organizer
      第64回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] MAGE-D1遺伝子欠損マウスに認められるうつ様行動におけるノルアドレナリン神経系の関与2021

    • Author(s)
      毛利 彰宏, 平川 茉実, 横山 美里, 渡辺 研, 木村 真理, 磯部 凌輔, 國澤 和生, 森 優子, 山本 康子, 野田 幸裕, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 前頭前皮質のmiR-874-3pはIDO1抑制を介してLPS誘発性のうつ様行動を緩解する2021

    • Author(s)
      國澤 和生, Suento Willy Jaya, Wulaer Bolati, 小菅 愛加, 飯田 翼, 藤垣 英嗣, 山本 康子, Tanra Andi Jayalangkara, 齋藤 邦明, 鍋島 俊隆, 毛利 彰宏
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 弱教師あり学習を用いたCT画像における特発性間質性肺炎の分類2021

    • Author(s)
      竹内野々子, 寺本篤司, 今泉和良, 齋藤邦明,藤田広志
    • Organizer
      医用画像情報学会 令和3年度秋季(第191回)大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 慢性的な社会的敗北ストレスによるうつ様行動は, ミクログリアの活性化を介した脳梁の髄鞘異常を伴う2021

    • Author(s)
      菅原 侑実香, 國澤 和生, 飯田 翼, 齋藤 成, 小菅 愛加, Bolati Wulaer, 山本 康子, 齋藤 邦明, 毛利 彰宏, 鍋島 俊隆
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 社会的敗北ストレス負荷によるうつ様行動はユビキチン化酵素Nedd4L発現低下によるグルタミン酸神経機能低下を介している2021

    • Author(s)
      小菅愛加、國澤和生、飯田 翼、齋藤邦明、鍋島俊隆、毛利彰宏
    • Organizer
      第139回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] キノリン酸代謝の低下はタウのリン酸化を亢進し、脳室拡大とドパミン神経期の低下と共に 運動・認知機能の障害を惹起する2021

    • Author(s)
      毛利 彰宏, 新島 萌, 國澤 和生, 齋藤 邦明, 鍋島 俊隆;
    • Organizer
      第43回生物学的精神医学会(BP)、第51回日本神経精神薬理学会(NP)合同年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] ビフィズス菌の加熱殺菌体は慢性社会的敗北ストレスにより誘発されるうつ様行動及びインターロイキン1βの発現を抑制する2021

    • Author(s)
      國澤和生、小菅愛加、菅原侑実香、篠原香月、飯田 翼、Bolati Wulaer、河合智貴、藤垣英嗣、山本康子、齋藤邦明、鍋島俊隆
    • Organizer
      第64回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Classification and Segmentation of Idiopathic Interstitial Pneumonia Using 3D U-Net2021

    • Author(s)
      Nonoko Takeuchi, Atsushi Teramoto, Kazuyoshi Imaizumi, Kuniaki Saito, Hiroshi Fujita,
    • Organizer
      IFMIA 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] Attention mechanism and weakly supervised learning solve complicated problems: Principles and application to IIPs classification2021

    • Author(s)
      N.Takeuchi, A.Teramoto, K.Imaizumi, K.Saito, H.Fujita
    • Organizer
      RSNA2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] 高食塩負荷により惹起される高血圧および行動異常は末梢炎症反応を伴う2021

    • Author(s)
      窪田 悠力, 毛利 彰宏, 國澤 和生, 長谷川 眞也, 倉橋 仁美, 山本 康子, 手塚 裕之, 釘田 雅則, 長尾 静子, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 社会的敗北ストレスは前頭前皮質でのGLT-1ユビキチン化低下を介して, うつ様行動を誘発する2021

    • Author(s)
      小菅 愛加, 國澤 和生, 飯田 翼, Wulaer Bolati, Suento Willy Jaya, 山本 康子, 齋藤 邦明, 毛利 彰宏, 鍋島 俊隆:
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] ニコチンは血清コルチコステロン量の増加を介した慢性予測不能軽度ストレスによるうつ様行動を緩解する2021

    • Author(s)
      長谷川 眞也, 毛利 彰宏, 國澤 和生, 窪田 悠力, 倉橋 仁美, 山本 康子, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] QPRTの欠損はキノリン酸によるドパミン作動性神経系における酸化ストレスを増強し、連動・認知機能障害を惹起する2021

    • Author(s)
      毛利彰宏、新島 萌、國澤和生、髙野 一輝、山田雅之、勅使河原知明、窪田悠力、平川茉実、森 優子、星 雅人、藤垣英嗣、山本康子、長谷川眞也、倉橋仁美、齋藤邦明、鍋島俊隆
    • Organizer
      第64回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 慢性予測不能軽度ストレスによる行動変化におけるミクログリアに関連したキヌレニン代謝の関与2021

    • Author(s)
      長谷川眞也、毛利彰宏、國澤和生、窪田悠力、倉橋仁美、山本康子、齋藤邦明、鍋島俊隆;
    • Organizer
      第64回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 3D U-Netを用いたCT画像における特発性間質性肺炎の領域抽出及び鑑別2020

    • Author(s)
      竹内野々子, 寺本篤司, 今泉和良, 齋藤邦明,藤田広志
    • Organizer
      医用画像情報学会 令和2年度秋季(第188回)大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] End-to-End Model for Analysis of Idiopathic Interstitial Pneumonia Using 3D U-Net2020

    • Author(s)
      Nonoko Takeuchi, Atsushi Teramoto, Kazuyoshi Imaizumi, Kuniaki Saito, Hiroshi Fujita,
    • Organizer
      第76回日本放射線技術学会総会学術大会
    • Data Source
      KAKENHI-PROJECT-20K08060
  • [Presentation] QPRTの欠損はキノリン酸によるドパミン作動性神経系における酸化ストレスを介した運動・認知機能障害を惹起する.2020

    • Author(s)
      毛利 彰宏、新島 萌、勅使河原 知明、國澤 和生、窪田 悠力、山本 康子、齋藤 邦明、鍋島 俊隆
    • Organizer
      第93回日本薬理学会年会(2020.3.16-18横浜)
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] トリプトファン代謝酵素Indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020

    • Author(s)
      石川雅樹、山本 康子, 藤垣 英嗣, 毛利 彰宏, 國澤 和生, 鍋島 俊隆, 齋藤 邦明
    • Organizer
      第61回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] トリプトファン代謝酵素 indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020

    • Author(s)
      石川雅樹、山本康子、齋藤邦明
    • Organizer
      第60回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020

    • Author(s)
      山本康子、藤垣英嗣、齋藤邦明
    • Organizer
      第67回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] トリプトファン-キヌレニン代謝を基軸とした創薬・診断薬開発~皮膚科免疫関連疾患を視野に入れて~2020

    • Author(s)
      齋藤邦明
    • Organizer
      第71回日本皮膚科学会中部支部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Lipopolysaccharide injection triggers Indoleamine-2,3-dioxygenase1 and miR-874-3p interaction which leads to depression-like behavior in mouse.2019

    • Author(s)
      Willy Jaya Suento, Kazuo Kunisawa, Bolati Wulaer, Tsubasa Iida, Aika Kosuge, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 糖尿病性腎症における代謝変容の役割の解明2019

    • Author(s)
      高橋和男、坪井直毅、長尾静子、齋藤邦明、湯澤由紀夫
    • Organizer
      第49回日本腎臓学会西部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08715
  • [Presentation] Alteration of Tryptophan-Kynurenine Metabolites in the Serum and Kidney in Diabetic Nephropathy2019

    • Author(s)
      Shoko Matsushita,Kazuo Takahashi,Ryosuke Umeda,Naotake Tsuboi,Kazuki Nakajima,1 Aya Yoshimura,1 Kanako Kumamoto,1 Masanori Kugita,1 Hidetsugu Fujigaki,1 Akihiro Mouri,1 Yasuko Yamamoto,1 Toshitaka Nabeshima,Mitsutoshi Setou,Shizuko Nagao,Kuniaki Saito,Yukio Yuzawa
    • Organizer
      Kidney Week 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08715
  • [Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する/ IDO1 regulates vulnerability to social defeat stress.2019

    • Author(s)
      國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆:
    • Organizer
      第42回日本神経科学大会第62回日本神経化学会大会合同大会(2019.7.25-28 新潟)
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] トリプトファン-キヌレニン代謝をターゲットとした創薬・診断薬開発2019

    • Author(s)
      齋藤邦明
    • Organizer
      第39回日本トリプトファン研究会学術集会(2019/12/14-15千葉)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] The deficit of quinolinic acid phosphoribosyltransferase induces hypolocomotion and cognitive impairment through impairment of dopaminergic neuronal function2019

    • Author(s)
      Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] IDO1 regulates vulnerability to social defeat stress2019

    • Author(s)
      國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆
    • Organizer
      NEURO2019(2019/7/25-28新潟)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 2型糖尿病性腎症モデルラットにおける腎組織中キノリン酸の分布解析2019

    • Author(s)
      松下祥子、高橋和男、吉村文、熊本海生航、伊藤辰将、坪井直毅、毛利彰宏3、山本 康子4、藤垣 英嗣4、中嶋和紀、釘田雅則、國澤和生、鍋島俊隆、齋藤邦明、瀬藤光利、長尾静子、湯澤由紀夫
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08715
  • [Presentation] Repeated social defeat stress induces depression-like behavior through the decrease of GLT-1 ubiquitination in the prefrontal cortex of mice.2019

    • Author(s)
      Aika Kosuge, Kazuo Kunisawa, Tsubasa Iida, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Repeated social defeat stress induces microglial activation and myelin abnormality in the corpus callosum: a potential link to depression-like behavior.2019

    • Author(s)
      Tsubasa Iida, Kazuo Kunisawa, Sei Saitoh, Aika Kosuge, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito and Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] The Role of Tryptophan Metabolism and Inflammation in Depression: The Target for Novel Diagnosis and Therapy藤2019

    • Author(s)
      齋藤邦明
    • Organizer
      藤田医科大学ブランディング事業国際シンポジウム(201910/14 名古屋)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice2019

    • Author(s)
      毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
    • Organizer
      NEURO2019(2019/7/25-28新潟)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 慢性予測不能軽度ストレス負荷は側坐核のドパミン機能亢進と前頭皮質・海馬のセロトニン機能低下を伴ううつ様行動を惹起する2019

    • Author(s)
      毛利 彰宏、キョヘイ ル、ヤン ヤン、國澤 和生、勅使河原 知明、平川 茉実、森 優子、山本 康子、シュウ リボ、鍋島 俊隆、齋藤 邦明
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 人工知能を用いたストレス負荷マウスの表情評価.2019

    • Author(s)
      多田遼矢,毛利彰宏,寺本篤司,國澤和生,山田あゆみ,長谷川眞也,倉橋仁美,浅野僚子,窪田悠力,新島萌,山本康子,齋藤邦明,鍋島俊隆
    • Organizer
      日本生体医工学会東海支部大会(2019.10.26名古屋)
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] The role of tryptophan metabolism in major depressive disorder2019

    • Author(s)
      Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Bolati Wulaer, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Deficiency of kynurenine 3-monooxygenase increases vulnerability to the PCP-induced behavioral abnormalities2019

    • Author(s)
      Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Impaired neurogenesis in the dentate gyrus of adult ShatiKO mice2019

    • Author(s)
      Bolati Wulaer, Kazuo Kunisawa, Willy Jaya Suento, Tsubasa Iida, Aika Kosuge, Atsumi Nitta, Akihiro Mouri, Kuniaki Saito Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Antidepressant effects of XJ-Et-8 in mice chronically exposed to corticosterone2019

    • Author(s)
      Jiajing Shan, Akihiro Mouri, Yang Yang, Qiaohui Lu, Kazuo Kunisawa , Tomoaki Teshigawara , Mami Hirakawa , Yuko Mori , Yasuko Yamamoto , Zou Libo , Toshitaka Nabeshima, Kuniaki Saito,
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Lipopolysaccharide injection triggers Indoleamine-2,3-dioxygenase1 and miR-874-3p interaction which leads to depression-like behavior in mouse2019

    • Author(s)
      Willy Jaya Suento, Kazuo Kunisawa, Bolati Wulaer, Tsubasa Iida, Aika Kosuge, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      AsCNP(2019/10/11-13福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice.2019

    • Author(s)
      毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
    • Organizer
      第42回日本神経科学大会第62回日本神経化学会大会合同大会(2019.7.25-28 新潟)
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-、2019

    • Author(s)
      毛利彰宏、國澤和生、窪田悠力、新島萌 、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
    • Organizer
      次世代を担う創薬・医療薬理シンポジウム2019(2019.8.31東京)
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Development of biomarker for depression focused on serotonergic systems from animal models.2019

    • Author(s)
      Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-2019

    • Author(s)
      毛利彰宏、國澤和生、窪田悠力、新島萌 、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
    • Organizer
      次世代を担う創薬・医療薬理シンポジウム2019(2019/8/31東京)
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する2019

    • Author(s)
      國澤 和生 毛利 彰宏 小菅 愛加 飯田 翼 Wulaer Bolati 山本 康子 齋藤 邦明 鍋島 俊隆
    • Organizer
      第42回日本神経科学大会第62回日本神経化学会大会合同大会(2019/7/24-27新潟)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 感染症におけるオミックス解析の応用2019

    • Author(s)
      齋藤邦明
    • Organizer
      第60回日本臨床ウイルス学会(2019/5/25名古屋)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Kynurenine 3-monooxygenase regulates expression of depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptor by kynurenic acid. AsCNP2019 (2019.10.11-13, 福岡)2019

    • Author(s)
      Akihiro Mouri, Yuko Mori, Kazuo Kunisawa, Mami Hirakawa, Tomoaki Teshigawara, Hisayoshi Kubota, Moe Niijima, Hidetsugu Fujigaki, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
    • Organizer
      AsCNP2019 (2019.10.11-13, 福岡)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Involvement of kynurenine 3-monooxygenase in the vulnerability to the PCP-induced behavioral abnormalities2018

    • Author(s)
      Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Tomoaki Teshigawara, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima ,Kuniaki Saito
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018

    • Author(s)
      Akihiro Mouri,Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, Toshitaka Nabeshima
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 薬学研究が支える臨床化学 精神疾患モデル動物研究からのバイオマーカー研究 薬学・医学から臨床化学へのトランスレーショナル研究2018

    • Author(s)
      毛利 彰宏, 國澤 和生, 山本 康子, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第58回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Lipopolysaccharide shock reveals the immune function of indoleamine 2, 3-dioxygenase 2 through regulation of IL-6/STAT3 signalling.2018

    • Author(s)
      1.Yasuko Yamamoto, Wakana Yamasuge, Shinjiro Imai, Kazuo Kunisawa, Masato Hoshi, Hidetsugu Fujigaki, Akihiro Mouri, Toshitaka Nabeshima, Kuniaki Saito.
    • Organizer
      15th International Society for Tryptophan Research Conference.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] Exposure to valproic acid during pregnancy induces autism endophenotypes in the male offspring2018

    • Author(s)
      Mami HIrakawa, Akihiro Mouri, Kazuo Kunisawa, Yuko Mori, Moe Niijima ,Hisayoki Kubota, Tomoaki Teshigawara, Hidetsugu Fujigaki, Toshitaka Nabeshima, Kuniaki Saito
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] DEVELOPMENT OF ANIMAL MODELS AND BIOMARKER FOR DEPRESSION FOCUSED ON SEROTONERGIC SYSTEMS2018

    • Author(s)
      Akihiro Mouri1, Kazuo Kunisawa2, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      15th International Society for Tryptophan Research (ISTRY) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Development of kynurenine aminotransferase II inhibitor screening assay.2018

    • Author(s)
      2.Kyoka Yamazaki, Hidetsugu Fujigaki, Yukihiro Yoshida, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito.
    • Organizer
      15th International Society for Tryptophan Research Conference.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] NGSを用いた小脳変性マウスのExome解析および原因遺伝子候補の神経栄養因子との関連 脳機能改善素材開発試験の応用を目指して2018

    • Author(s)
      別府 秀彦, 稲垣 秀人, 西井 一宏, 新里 昌功, 千原 猛, 毛利 彰宏, 齋藤 邦明, 高橋 久英, 倉橋 浩樹
    • Organizer
      第16回日本機能性食品医用学会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 酵素反応を用いたキノリン酸測定法の開発2018

    • Author(s)
      山崎 杏佳, 藤垣 英嗣, 吉田 幸弘, 木村 文香, 山本 康子, 齋藤 邦明
    • Organizer
      第58回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Development of animal models and biomarker for depression focused on serotonergic systems2018

    • Author(s)
      Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto , Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      15th International Society for Tryptophan Research (ISTRY) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Repeated social defeat induces social interaction deficits associated with the alteration of kynurenine pathway activity in the prefrontal cortex2018

    • Author(s)
      Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] ストレス(モデル)と分子 うつ病発症におけるトリプトファン代謝の関与2018

    • Author(s)
      國澤 和生, 毛利 彰宏, 山本 康子, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第34回日本ストレス学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 神経精神疾患の病態メカニズムに基づく新たな治療分子標的 トリプトファン代謝に注目したうつ病病態解明と診断・治療薬戦略2018

    • Author(s)
      毛利 彰宏, 國澤 和生, 山本 康子, 藤垣 英嗣, 齋藤 邦明, 鍋島 俊隆
    • Organizer
      第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] Involvement of kynurenine pathway in behavioral impairments in the offspring induced by the prenatal poly I: C injection2018

    • Author(s)
      Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Toshitaka Nabeshima, Kuniaki Saito
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 10年後の臨床化学を考える 診断薬開発の未来 求められる先制診断システム2018

    • Author(s)
      齋藤邦明
    • Organizer
      第58回日本臨床化学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] MAGE-D1 REGULATES EXPRESSION OF DEPRESSION-LIKE BEHAVIOR THROUGH SEROTONIN TRANSPORTER UBIQUITYLATION2018

    • Author(s)
      Akihiro Mouri, Kazuo Kunisawa, Mami Hirakawa, Yuko Mori, Ken Watanabe, Hidetsugu Fujigaki, Yasuko Yamamoto, Yukihiro Noda, Kuniaki Saito, Toshitaka Nabeshima
    • Organizer
      15th International Society for Tryptophan Research (ISTRY) Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Kynurenine 3-monooxygenase is essential for de novo biosynthesis of NAD+.2018

    • Author(s)
      3.Yukihiro Yoshida, Hidetsugu Fujigaki, Yasuko Yamamoto, Kyoka Yamazaki, Fumika Kimura, Hisako Kubo, Tsutomu Fukuwatari, Toshitaka Nabeshima, Kuniaki Saito.
    • Organizer
      15th International Society for Tryptophan Research Conference.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018

    • Author(s)
      Akihiro Mouri, Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, TOshitaka Nabeshima
    • Organizer
      WCP2018 Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] うつ病発症におけるトリプトファン代謝の関与2018

    • Author(s)
      國澤和生、毛利彰宏、山本康子、齋藤邦明、鍋島俊隆
    • Organizer
      第34回日本ストレス学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018

    • Author(s)
      松下 祥子, 高橋 和男, 伊藤 辰将, 山本 康子, 藤垣 英嗣, 毛利 彰宏, 中嶋 和紀, 尾之内 高慶, 辰川 英樹, 釘田 雅則, 長尾 静子, 人見 清隆, 齋藤 邦明, 瀬藤 光利, 湯澤 由紀夫
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19761
  • [Presentation] 酵素法を用いたキヌレニン定量法の開発.2017

    • Author(s)
      吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
    • Organizer
      第57回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討.2017

    • Author(s)
      藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
    • Organizer
      第57回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Depressive symptoms and L-Tryptophan -Kynurenine pathway metabolism focus on neuro-inflammation.2017

    • Author(s)
      Kuniaki Saito
    • Organizer
      The 5th Congress of Asian College pof Neuropsychopharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 酵素法を用いたキヌレニン定量法の開発.2017

    • Author(s)
      吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
    • Organizer
      第57回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] RA患者の血中インフリキシマブ濃度測定の意義2017

    • Author(s)
      竹村正男、佐藤正夫、伊藤弘養、 清島 満、齋藤邦明
    • Organizer
      第64回日本臨床検査医学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 先制医療の実現のために ~次世代創薬・診断薬開発~2017

    • Author(s)
      齋藤邦明
    • Organizer
      臨床検査薬協会・技術委員会総会
    • Place of Presentation
      ヒューリックカンファレンスルーム(東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Depressive symptoms and L-Tryptophan -Kynurenine pathway metabolism focus on neuro-inflammation.2017

    • Author(s)
      Kuniaki Saito
    • Organizer
      The 5th Congress of Asian College pof Neuropsychopharmacology( 2017.4.27-29, Indonesia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04252
  • [Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発.2017

    • Author(s)
      吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
    • Organizer
      第38回日本トリプトファン研究会学術集
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] 脳神経疾患における治療標的としてのトリプトファン-キヌレニン代謝酵素2017

    • Author(s)
      齋藤邦明
    • Organizer
      第23回脳の医学・生物学研究会
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発.2017

    • Author(s)
      吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
    • Organizer
      第38回日本トリプトファン研究会学術集
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討.2017

    • Author(s)
      藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
    • Organizer
      第57回日本臨床化学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-17H07222
  • [Presentation] アストログリアにおけるMHCIの発現とその行動学的・神経病理学的影響2017

    • Author(s)
      祖父江顕,伊藤教道,羽田和弘,中島晶,村上由希,毛利彰宏,山本康子,鍋島俊隆,齋藤邦明,永井拓,山田清文
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 周産期における抑うつにおけるユビキチン化セロトニントランスポーターの変化2016

    • Author(s)
      毛利彰宏、椎野智子、勅使河原知明、山本康子、野田幸裕、尾崎紀夫、齋藤邦明、鍋島俊隆 「
    • Organizer
      第56回日本臨床化学会学術大会
    • Place of Presentation
      熊本県民交流館パレア(熊本)
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016

    • Author(s)
      勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
    • Organizer
      第56回日本臨床化学会学術大会
    • Place of Presentation
      熊本県民交流館パレア(熊本)
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016

    • Author(s)
      勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
    • Organizer
      第56回日本臨床化学会学術大会
    • Place of Presentation
      熊本県民交流館パレア(熊本)
    • Data Source
      KAKENHI-PROJECT-26460675
  • [Presentation] 健常時からの暦年的バイオバンクの活用 -代謝変容に着目したバイオマーカー検索-2015

    • Author(s)
      斉藤邦明
    • Organizer
      第55回日本臨床化学会年次学術集会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 先制医療を実現するためのバイオバンク2015

    • Author(s)
      斉藤邦明
    • Organizer
      第62回日本臨床検査医学会学術集会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 先制医療実現のために ー不健康を科学するー2015

    • Author(s)
      斉藤邦明
    • Organizer
      日本健康科学会第31回学術集会・次期学術集会長講演
    • Place of Presentation
      ホテルグランドヒル市ヶ谷(東京)
    • Year and Date
      2015-08-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] Increased serum GP88(progranulin) concentration in rheumatoid arthritis.2015

    • Author(s)
      Yamamoto Y, Saito K
    • Organizer
      IFCC Paris
    • Place of Presentation
      Le Palais des Congres de paris(France)
    • Year and Date
      2015-06-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670278
  • [Presentation] RA患者におけるバイオマーカー GP88の検討2015

    • Author(s)
      竹村正男、佐藤正夫、山本康子、 斎藤邦明
    • Organizer
      第27回中部リウマチ学会
    • Place of Presentation
      ウインクあいち(名古屋市)
    • Year and Date
      2015-09-04
    • Data Source
      KAKENHI-PROJECT-26670278
  • [Presentation] The role of L-tryptophan metabolism via indoleamine 2,3-dioxygenase on cytokine-induced depressive symptoms2015

    • Author(s)
      Saito K
    • Organizer
      ISTRY conference Symposium Pathology III
    • Place of Presentation
      Grand Rapids( USA)
    • Year and Date
      2015-09-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03086
  • [Presentation] 関節リウマチ症例における血清Progranulinの測定2015

    • Author(s)
      山本康子, 竹村正男, 佐藤正夫, 斉藤邦明
    • Organizer
      第55回日本臨床化学会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-26670278
  • [Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2013

    • Author(s)
      Saito,K
    • Organizer
      8th International Conference of Clinical Laboratory Automation
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Data Source
      KAKENHI-PROJECT-23650417
  • [Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of indoleamine 2,3-dioxygenase 12013

    • Author(s)
      S Imai, R Yamamoto, Y Yamamoto, Y Katayanagi, R Fukutomi, M Abe, Y Ozawa, K Saito
    • Organizer
      15thInternational Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] 免疫調節因子インドールアミン 2,3-ジオキシゲナーゼ1の新規阻害剤探索:フィトケミカルを中心として2013

    • Author(s)
      山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] 免疫調節因子インドールアミン 2, 3-ジオキシゲナーゼ1の新規阻害剤探索 : フィトケミカルを中心として2013

    • Author(s)
      山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
    • Organizer
      第36回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] 疾患メタボローム・疾患プロテオミクス解析2013

    • Author(s)
      斉藤邦明
    • Place of Presentation
      仙台市
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spec trometry2013

    • Author(s)
      Saito, K
    • Organizer
      8th International Conference of Clinica l Laboratory Automation
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of in doleamine 2, 3-dioxygenase 12013

    • Author(s)
      Imai, R Yamamoto, Y Yamamoto, Y Katayan agi, R Fukutomi, M Abe, Y Ozawa, K Saito
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] Is the measurement of Ca2+-release inCD19+ B cells stimulated by statin useful for prediction of muscle damage as a side effect?2012

    • Author(s)
      Mori I, Hattori T, Osawa Y, Kanamori H, Kajita K, Morita H, Ishizuka T, Saito K, Ito H, Seishima M
    • Organizer
      第44回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-21390179
  • [Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012

    • Author(s)
      Saito K
    • Organizer
      8th International Conference of Clinical Laboratory Automation
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390149
  • [Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012

    • Author(s)
      Saito K
    • Organizer
      8th International Conference of Clinical Laboratory Automation
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23650417
  • [Presentation] 高脂血症治療剤による培養細胞に対するCa^<2+>放出効果の基礎的検討2010

    • Author(s)
      服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
    • Organizer
      第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海北陸支部例会連合大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-21390179
  • [Presentation] Ca2+releasing effect of stains on human CD19+primary B cells.2010

    • Author(s)
      Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
    • Organizer
      第42回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      岐阜市
    • Year and Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-21390179
  • [Presentation] Ca^<2+> releasing effect of statins on human CD19+ primary B cells2010

    • Author(s)
      Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
    • Organizer
      第42回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      岐阜市
    • Year and Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-21390179
  • [Presentation] 高脂血症治療剤による培養細胞に対するCa2+放出効果の基礎的検討2010

    • Author(s)
      服部高幸、竹村正男、太田浩敏、 大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島 満
    • Organizer
      第49回日本臨床検査医学会東海・北陸支部総会 第320回日本臨床化学会東海・北陸支部例会 連合大会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-21390179
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