Hamamoto Ryuji 浜本隆二

… Alternative Names

HAMAMOTO Ryuji 浜本隆二

浜本隆二ハマモトリュウジ

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Researcher Number	80321800
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External Links
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 分野長 2025: 国立研究開発法人理化学研究所, 革新知能統合研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人理化学研究所, 革新知能統合研究センター, チームリーダー 2018 – 2023: 国立研究開発法人国立がん研究センター, 研究所, 分野長 2009 – 2013: 東京大学, 医科学研究所, 助教 2005: 東京大学, 医科学研究所, 助手 2003: 東京大学, 医科学研究所, 助手 2000: 理化学研究所, 抗生物質研究室, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Medical genome science / 生物・生体工学 Except Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 49020:Human pathology-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 62010:Life, health and medical informatics-related / Basic Section 55050:Anesthesiology-related / Science and Engineering / Biological Sciences
Keywords	Principal Investigator 分泌型プロテオグリカン / OMD / パスウェイ解析 / トランスクリプトーム解析 / SLRP family / 併用療法 / PRELP / ヒストン脱アセチル化酵素阻害剤 / がん抑制遺伝子 / 階層的ネットワーク構造 … More / がんの統合的解明 / NP困難 / end-to-end学習 / Diet Networks / 多層オミックス / 深層学習 / グラフ構造 / 人工知能技術 / 機械学習技術 / 深層学習技術 / 多層オミックスデータ / がん / がんの分子標的治療薬 / エピジェネティクス / タンパク質メチル化 / Reveromycin A / 低分子プローブ / 分化誘導 / 肝特異的転写因子 / バイオ人工肝臓 … More Except Principal Investigator マルチオミックス解析 / ChIP-seq / isoavenaciolide / phoslactomycin / ゲノム・エピゲノム / 創薬ターゲット / 予後予測因子 / 肺がん / AI病理学 / デジタル病理学 / 病理組織 / 治療効果予測 / 形態学的バイオマーカー / エピゲノム / ロボット / ロボット技術 / 人工知能 / 卵巣がん / シングルセル解析 / 機械学習・深層学習 / ATAC-seq / オミックス解析 / エピジェネティックス / エピジェネティクス / ロボティクス / データマイニング / バイオインフォマティクス / ホールゲノムシークエンス / 環状RNA / 血小板 / 敗血症 / dephosphorylation / apoptosis / biosynthesis / inhibitor / phosphatase / テトロン酸 / 分子設計 / RK-682 / 活性中心 / Michael付加 / VHR / 4-isoavenaciolide / リン酸化 / Bcl-2 / 脱リン酸化 / アポトーシス / 生合成系 / 阻害剤 / ホスファターゼ / 治療 / 診断 / マイクロアレイ / 癌 / ゲノム Less

エンハンサー領域に着目した肺がんpan-negative症例の統合オミックス解析
- Principal Investigator
  
  浅田健
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Institute of Physical and Chemical Research
Development study on pathological predictive biomarkers for cancer treatment
- Principal Investigator
  
  元井紀子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Research Institute for Clinical Oncology Saitama Cancer Center
Next generation epigenomics using artificial intelligence and robotics in ovarian cancer
- Principal Investigator
  
  Komatsu Masaaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Institute of Physical and Chemical Research
Integrated functional analysis of the novel tumor suppressor genes OMD and PRELP, and their application to treatment of cancerPrincipal Investigator
- Principal Investigator
  
  Hamamoto Ryuji
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  National Cancer Center Japan
敗血症患者における血小板内環状RNAの解析
- Principal Investigator
  
  境倫宏
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Mie University
Construction of a multilayered integrated epigenetics database based on machine learning and deep learning
- Principal Investigator
  
  Kaneko Syuzo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Cancer Center Japan
がんの統合的解明を目指した生体情報の階層的ネットワーク構造に対する深層学習の応用Principal Investigator
- Principal Investigator
  
  浜本隆二
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  National Cancer Center Japan
タンパク質メチル化を標的とした新規がんの分子標的治療薬の開発Principal Investigator
- Principal Investigator
  
  浜本隆二
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical genome science
- Research Institution
  The University of Tokyo
Development of new diagnostic and therapeutic approaches based on information of the human genome
- Principal Investigator
  
  FURUKAWA Yoichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
バイオ人工肝臓構築を目指した、低分子薬剤による株化肝細胞の分化誘導システムの構築Principal Investigator
- Principal Investigator
  
  浜本隆二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  The Institute of Physical and Chemical Research
Chemical biology study on protein phosphatases and their specific inhibitors.
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  RIKEN

[Book] 実験医学2019年10月号2019
- Author(s)
  浜本　隆二
- Total Pages
  145
- Publisher
  羊土社
- ISBN
  4758125244
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Book] iｎｓｉｌｉｃｏ創薬におけるスクリーニングの高速化・高精度化技術2018
- Author(s)
  浜本　隆二
- Total Pages
  540
- Publisher
  技術情報協会
- ISBN
  9784861046889
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Journal Article] Analysis of super-enhancer using machine learning and its application to medical biology2023
- Author(s)
  Hamamoto Ryuji、Takasawa Ken、Shinkai Norio、Machino Hidenori、Kouno Nobuji、Asada Ken、Komatsu Masaaki、Kaneko Syuzo
- Journal Title
  
  Briefings in Bioinformatics
  
  Volume: - Issue: 3
- DOI
  10.1093/bib/bbad107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519
[Journal Article] Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability2023
- Author(s)
  Takasawa K, Asada K, Kaneko S, Shiraishi K, Machino H, Takahashi S, Shinkai N, Kouno N, Kobayashi K, Komatsu M, Mizuno T, Okubo Y, Mukai M, Yoshida T, Yoshida Y, Horinouchi H, Watanabe S, Ohe Y, Yatabe Y, Kohno T, Hamamoto R
- Journal Title
  
  Experimental and Molecular Medicine
  
  Volume: 56 Issue: 3 Pages: 646-655
- DOI
  10.1038/s12276-024-01173-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-22K07681, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-23K27449
[Journal Article] Introducing AI to the molecular tumor board: one direction toward the establishment of precision medicine using large-scale cancer clinical and biological information2022
- Author(s)
  Hamamoto R, Koyama T, Kouno N, Yasuda T, Yui S, Sudo K, Hirata M, Sunami K, Kubo T, Takasawa K, Takahashi S, Machino H, Kobayashi K, Asada K, Komatsu M, Kaneko S, Yatabe Y, Yamamoto N
- Journal Title
  
  Experimental Biology and Oncology
  
  Volume: 11 Issue: 1 Pages: 8-8
- DOI
  10.1186/s40164-022-00333-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-23K24468
[Journal Article] PRELP Regulates Cell-Cell Adhesion and EMT and Inhibits Retinoblastoma Progression2022
- Author(s)
  Hopkins Jack、Asada Ken、Leung Alex、Papadaki Vasiliki、Davaapil Hongorzul、Morrison Matthew、Orita Tomoko、Sekido Ryohei、Kosuge Hirofumi、Reddy M. Ashwin、Kimura Kazuhiro、Mitani Akihisa、Tsumoto Kouhei、Hamamoto Ryuji、Sagoo Mandeep S.、Ohnuma Shin-ichi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 19 Pages: 4926-4926
- DOI
  10.3390/cancers14194926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-22KJ0925, KAKENHI-PROJECT-20K09805
[Journal Article] Tumor Suppressive Role of the PRELP Gene in Ovarian Clear Cell Carcinoma2022
- Author(s)
  Dozen Ai、Shozu Kanto、Shinkai Norio、Ikawa Noriko、Aoyama Rina、Machino Hidenori、Asada Ken、Yoshida Hiroshi、Kato Tomoyasu、Hamamoto Ryuji、Kaneko Syuzo、Komatsu Masaaki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 12 Pages: 1999-1999
- DOI
  10.3390/jpm12121999
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-21H03550
[Journal Article] Appkication of non-negative matrix fractorization in oncology: one approach for establishing precision medicine2022
- Author(s)
  Hamamoto R, Takasawa K, Machino H, Kobayashi K, Takahashi S, Bolatkan A, Shinkai N, Sakai A, Aoyama R, Yamada M, Asada K, Komatsu M, Okamoto K, Kameoka H, Kaneko S
- Journal Title
  
  Briefings in Bioinformatics
  
  Volume: 23 Issue: 4
- DOI
  10.1093/bib/bbac246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03550
[Journal Article] Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer2022
- Author(s)
  Shozu Kanto、Kaneko Syuzo、Shinkai Norio、Dozen Ai、Kosuge Hirofumi、Nakakido Makoto、Machino Hidenori、Takasawa Ken、Asada Ken、Komatsu Masaaki、Tsumoto Kouhei、Ohnuma Shin-Ichi、Hamamoto Ryuji
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 14 Issue: 1 Pages: 1-13
- DOI
  10.1186/s13148-022-01370-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-22KJ0925
[Journal Article] The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma2022
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Noriko Ikawa, Ken Asada, Ryuichiro Nakato, Kanto Shozu, Ai Dozen, Kenbun Sone, Hiroshi Yoshida, Tomoyasu Kato, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii, Gottfried von Keudell, Vassiliki Saloura, Ryuji Hamamoto
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 39-39
- DOI
  10.1038/s42003-021-02992-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03074
[Journal Article] Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology2021
- Author(s)
  Ken Asada, Syuzo Kaneko, Ken Takasawa, Hidenori Machino, Satoshi Takahashi, Norio Shinkai, Ryo Shimoyama, Masaaki Komatsu, Ryuji Hamamoto
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 666937-666937
- DOI
  10.3389/fonc.2021.666937
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-21H03550
[Journal Article] Identification of the mutation signature of the cancer genome caused by irradiation2021
- Author(s)
  Kageyama Shun-Ichiro、Du Junyan、Kaneko Syuzo、Hamamoto Ryuji、Yamaguchi Shigeo、Yamashita Riu、Okumura Masayuki、Motegi Atsushi、Hojo Hidehiro、Nakamura Masaki、Tsuchihara Katsuya、Akimoto Tetsuo
- Journal Title
  
  Radiotherapy and Oncology
  
  Volume: 155 Pages: 10-16
- DOI
  10.1016/j.radonc.2020.10.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-18K11542
[Journal Article] Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential2021
- Author(s)
  Kaneko S、Mitsuyama T、Shiraishi K、Ikawa N、Shozu K、Dozen A、Machino H、Asada K、Komatsu M、Kukita A、Sone K、Yoshida H、Motoi N、Hayami S、Yoneoka Y、Kato T、Kohno T、Natsume T、Keudell GV、Saloura V、Yamaue H、Hamamoto R
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 9 Pages: 2126-2126
- DOI
  10.3390/cancers13092126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-20H03820
[Journal Article] C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation2021
- Author(s)
  Ozawa T、Kaneko S、Szulzewsky F、Qiao Z、Takadera M、Narita Y、Kondo T、Holland EC、Hamamoto R、Ichimura K
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 9 Issue: 1 Pages: 36-36
- DOI
  10.1186/s40478-021-01135-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09518
[Journal Article] Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data2020
- Author(s)
  Takahashi Satoshi、Asada Ken、Takasawa Ken、Shimoyama Ryo、Sakai Akira、Bolatkan Amina、Shinkai Norio、Kobayashi Kazuma、Komatsu Masaaki、Kaneko Syuzo、Sese Jun、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 10 Pages: 1460-1460
- DOI
  10.3390/biom10101460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17982, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients2020
- Author(s)
  Hirose S, Murakami N, Takahashi K, Kuno I, Takayanagi D, Asami Y, Matsuda M, Shimada Y, Yamano S, Sunami K, Yoshida K, Honda T, Nakahara T, Watanabe T, Komatsu M, Hamamoto R, Kato MK, Matsumoto K, Okuma K, Kuroda T, Okamoto A, Itami J, Kohno T, Kato T, Shiraishi K, Yoshida H
- Journal Title
  
  Gynecologic Oncology
  
  Volume: 156 Issue: 1 Pages: 203-210
- DOI
  10.1016/j.ygyno.2019.10.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11297, KAKENHI-PROJECT-18K15654, KAKENHI-PROJECT-19K17669, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Two Secreted Proteoglycans, Activators of Urothelial Cell?Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression2020
- Author(s)
  Papadaki V, Asada K, Watson JK, Tamura T, Leung A, Hopkins J, Dellett M, Sasai N, Davaapil H, Nik-Zainal S, Longbottom R, Nakakido M, Torii R, Veerakumarasivam A, Kaneko S, Sagoo MS, Murphy G, Mitani A, Tsumoto K, Kelly JD, Hamamoto R, Ohnuma SI
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 11 Pages: 3362-3362
- DOI
  10.3390/cancers12113362
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Critical Roles of N6-Methyladenosine (m6A) in Cancer and Virus Infection2020
- Author(s)
  Asada Ken、Bolatkan Amina、Takasawa Ken、Komatsu Masaaki、Kaneko Syuzo、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 7 Pages: 1071-1071
- DOI
  10.3390/biom10071071
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-18K05550
[Journal Article] Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer2020
- Author(s)
  Wada Miku、Kukita Asako、Sone Kenbun、Hamamoto Ryuji、Kaneko Syuzo、Komatsu Masaaki、Takahashi Yu、Inoue Futaba、Kojima Machiko、Honjoh Harunori、Taguchi Ayumi、Kashiyama Tomoko、Miyamoto Yuichiro、Tanikawa Michihiro、Tsuruga Tetsushi、Mori-Uchino Mayuyo、Wada-Hiraike Osamu、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 12 Pages: 1686-1686
- DOI
  10.3390/biom10121686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K11542
[Journal Article] Uncovering Prognosis-Related Genes and Pathways by Multi-Omics Analysis in Lung Cancer2020
- Author(s)
  Asada Ken、Kobayashi Kazuma、Joutard Samuel、Tubaki Masashi、Takahashi Satoshi、Takasawa Ken、Komatsu Masaaki、Kaneko Syuzo、Sese Jun、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 4 Pages: 524-524
- DOI
  10.3390/biom10040524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-18K05550
[Journal Article] Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine2020
- Author(s)
  Hamamoto Ryuji、Suvarna Kruthi、Yamada Masayoshi、Kobayashi Kazuma、Shinkai Norio、Miyake Mototaka、Takahashi Masamichi、Jinnai Shunichi、Shimoyama Ryo、Sakai Akira、Takasawa Ken、Bolatkan Amina、Shozu Kanto、Dozen Ai、Machino Hidenori、Takahashi Satoshi、Asada Ken、Komatsu Masaaki、Sese Jun、Kaneko Syuzo
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 12 Pages: 3532-3532
- DOI
  10.3390/cancers12123532
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development2020
- Author(s)
  Isago Hideaki、Mitani Akihisa、Mikami Yu、Horie Masafumi、Urushiyama Hirokazu、Hamamoto Ryuji、Terasaki Yasuhiro、Nagase Takahide
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 62 Issue: 2 Pages: 256-266
- DOI
  10.1165/rcmb.2019-0218oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17628, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-16K09575, KAKENHI-PROJECT-17K09630
[Journal Article] A Positive Correlation Between the EZH2 and PD-L1 Expression in Resected Lung Adenocarcinomas2019
- Author(s)
  Toyokawa Gouji、Takada Kazuki、Tagawa Tetsuzo、Hamamoto Ryuji、Yamada Yuichi、Shimokawa Mototsugu、Oda Yoshinao、Maehara Yoshihiko
- Journal Title
  
  The Annals of Thoracic Surgery
  
  Volume: 107 Issue: 2 Pages: 393-400
- DOI
  10.1016/j.athoracsur.2018.08.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15645, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-17K14994
[Journal Article] Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine2019
- Author(s)
  Hamamoto Ryuji、Komatsu Masaaki、Takasawa Ken、Asada Ken、Kaneko Syuzo
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 1 Pages: 62-62
- DOI
  10.3390/biom10010062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09768, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma2019
- Author(s)
  Kim Sangchul、Bolatkan Amina、Kaneko Syuzo、Ikawa Noriko、Asada Ken、Komatsu Masaaki、Hayami Shinya、Ojima Hidenori、Abe Nobutsugu、Yamaue Hiroki、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 9 Issue: 12 Pages: 810-810
- DOI
  10.3390/biom9120810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-19H03429
[Journal Article] Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro2019
- Author(s)
  Matsuno Yusuke、Atsumi Yuko、Shimizu Atsuhiro、Katayama Kotoe、Fujimori Haruka、Hyodo Mai、Minakawa Yusuke、Nakatsu Yoshimichi、Kaneko Syuzo、Hamamoto Ryuji、Shimamura Teppei、Miyano Satoru、Tsuzuki Teruhisa、Hanaoka Fumio、Yoshioka Ken-ichi
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 3925-3925
- DOI
  10.1038/s41467-019-11760-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04908, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-19H03429
[Journal Article] A Population-based Statistical Model for Investigating Heterogeneous Intraprostatic Sensitivity to Radiation Toxicity After 125I Seed Implantation2019
- Author(s)
  KOBAYASHI KAZUMA、MURAKAMI NAOYA、TAKAHASHI KANA、INABA KOJI、IGAKI HIROSHI、HAMAMOTO RYUJI、ITAMI JUN
- Journal Title
  
  In Vivo
  
  Volume: 33 Issue: 6 Pages: 2103-2111
- DOI
  10.21873/invivo.11710
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-16K10410
[Journal Article] The novel prognostic marker, EHMT2, is involved in cell proliferation via HSPD1 regulation in breast cancer2019
- Author(s)
  Seon-Kyu Kim, Kwangho Kim, Jea-Woon Ryu, Tae-Young Ryu, Jung Hwa Lim, Jung-Hwa Oh, Jeong-Ki Min, Cho-Rok Jung, Ryuji Hamamoto, Mi-Young Son, Dae-oo Kim, Hyun-Soo Ch
- Journal Title
  
  International Journal of Oncology
  
  Volume: 54 Pages: 65-76
- DOI
  10.3892/ijo.2018.4608
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Journal Article] Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy2019
- Author(s)
  Yamada Masayoshi、Saito Yutaka、Imaoka Hitoshi、Saiko Masahiro、Yamada Shigemi、Kondo Hiroko、Takamaru Hiroyuki、Sakamoto Taku、Sese Jun、Kuchiba Aya、Shibata Taro、Hamamoto Ryuji
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 14465-14465
- DOI
  10.1038/s41598-019-50567-5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Local Radiotherapy or Chemotherapy for Oligo-recurrent Cervical Cancer in Patients With Prior Pelvic Irradiation2019
- Author(s)
  KOBAYASHI KAZUMA、MURAKAMI NAOYA、TAKAHASHI KANA、INABA KOJI、HAMAMOTO RYUJI、ITAMI JUN
- Journal Title
  
  In Vivo
  
  Volume: 33 Issue: 5 Pages: 1659-1665
- DOI
  10.21873/invivo.11652
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma.2018
- Author(s)
  Shigekawa Y, Hayami S, Ueno M, Miyamoto A, Suzaki N, Kawai M, Hirono S, Okada KI, Hamamoto R, Yamaue H.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 76 Pages: 34320-34335
- DOI
  10.18632/oncotarget.26144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10675, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-16K15623
[Journal Article] Clinical Value of Serum p53 Antibody in the Diagnosis and Prognosis of Esophageal Squamous Cell Carcinoma2018
- Author(s)
  Kunizaki M, Hamasaki K, Wakata K, Tobinaga S, Sumida Y, Hidaka S, Yasutake T, Miyazaki T, Matsumoto K, Yamasaki T, Sawai T, Hamamoto R, Nanashima A, Nagayasu T
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 3 Pages: 1807-1813
- DOI
  10.21873/anticanres.12419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02106, KAKENHI-PUBLICLY-18H04908
[Journal Article] Prevalence of Enhancer of Zeste Homolog 2 in Patients with Resected Small Cell Lung Cancer2018
- Author(s)
  TOYOKAWA GOUJI、TAKADA KAZUKI、TAGAWA TETSUZO、KINOSHITA FUMIHIKO、KOZUMA YUKA、MATSUBARA TAICHI、HARATAKE NAOKI、TAKAMORI SHINKICHI、AKAMINE TAKAKI、HIRAI FUMIHIKO、YAMADA YUICHI、HAMAMOTO RYUJI、ODA YOSHINAO、MAEHARA YOSHIHIKO
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 6 Pages: 3707-3711
- DOI
  10.21873/anticanres.12649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15645, KAKENHI-PUBLICLY-18H04908
[Journal Article] The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.2013
- Author(s)
  Kang D, Cho HS, Toyokawa G, Kogure M, Yamane Y, Iwai Y, Hayami S, Tsunoda T, Field HI, Matsuda K, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R.
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 52 Issue: 2 Pages: 126-139
- DOI
  10.1002/gcc.22012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134008, KAKENHI-PROJECT-22681030
[Journal Article] Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of aurora kinase B2012
- Author(s)
  Hyun-Soo Cho, Shinya Hayami, Gouji Toyokawa, Kazuhiro Maejima, Yuka Yamane, Takehiro Suzuki, Naoshi Dohmae, Masaharu Kogure, Daechun Kang, David E, Neal, Bruce, A. J. Ponder, Hiroki Yamaue, Yusuke Nakamura, Ryuji Hamamoto
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 1072-1072
- DOI
  10.1038/ncomms2074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030, KAKENHI-PROJECT-23650624, KAKENHI-PROJECT-24390145, KAKENHI-PROJECT-221S0001
[Journal Article] Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression2012
- Author(s)
  Masashi Takawa, Hyun-Soo Cho, Shinya Hayami, Gouji Toyokawa, Masaharu Kogure, Yuka Yamane, Yukiko Iwai, Kazuhiro Maejima, Koji Ueda, Akiko Masuda, Naoshi Dohmae, Helen I. Field, Tatsuhiko Tsunoda, Takaaki Kobayashi, Takayuki Akasu, Masanori Sugiyama, Shin-ichi Ohnuma, Yutaka Atomi, Bruce A. J. Ponder, Yusuke Nakamura, Ryuji Hamamoto
- Journal Title
  
  Cancer Research
  
  Volume: 72 Pages: 3217-3227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] B1 Methylation by SMYD2 Enhances Cell Cycle Progression through an Increase of RB1 Phosphorylation2012
- Author(s)
  Hyun-Soo Cho. Shinya Hayami, Gouji Toyokawa, Kazuhiro Maejima, Yuka Yamane, Takehiro Suzuki, Naoshi Dohmae, Masaharu Kogure, Daechun Kang, David E. Neal, Bruce A. J. Ponder, Hiroki Yamaue, Yusuke Nakamura, Ryuji Hamamoto
- Journal Title
  
  Neoplasia
  
  Volume: 14 Pages: 476-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Recognition of modification status on a histone H3 tail by linked histone reader modules of UHRF12012
- Author(s)
  Kyohei Arita, Shin Isogai, Takashi Oda, Motoko Unoki, Kazuya Sugita, Naotaka Sekiyama, Keiko Kuwata, Ryuji Hamamoto Hidehito Tochio, Mamoru Sato, Mariko Ariyoshi, Masahiro
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Pages: 12950-12955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G(1)/S transition in cancer cells via transcriptional regulation of the HOXA1 gene2011
- Author(s)
  Cho HS, Toyokawa G, Daigo Y, Hayami S, Masuda K, Ikawa N, Yamane Y, Maejima K, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R
- Journal Title
  
  Int J Cancer
  
  Volume: (in press) Issue: 3
- DOI
  10.1002/ijc.26501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390178, KAKENHI-PLANNED-22134008, KAKENHI-PROJECT-22681030
[Journal Article] Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells2011
- Author(s)
  Cho HS, Suzuki T, Dohmae N, Hayami S, Unoki M, Yoshimatsu M, Toyokawa G, Takawa M, Chen T, Kurash JK, Field HI, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  Cancer Research
  
  Volume: 71 Pages: 655-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer2011
- Author(s)
  Toyokawa G, Masuda K, Daigo Y, Cho HS, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Chino M, Field HI, Neal DE, Tsuchiya E, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R
- Journal Title
  
  Mol Cancer
  
  Volume: 13 Pages: 65-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker2011
- Author(s)
  Takawa M, Masuda K, Kunizaki M, Daigo Y, Takagi K, Iwai Y, Cho HS, Toyokawa G, Yamane Y, Maejima K, Field HI, Kobayashi T, Akasu T, Sugiyama M, Tsuchiya E, Atomi Y, Ponder BA, Nakamura Y, Hamamoto R.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 7 Pages: 1298-1305
- DOI
  10.1111/j.1349-7006.2011.01958.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390178, KAKENHI-PROJECT-22681030, KAKENHI-PROJECT-221S0001
[Journal Article] The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 62011
- Author(s)
  Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R
- Journal Title
  
  Cancer Prev Res (Phila)
  
  Volume: 4 Pages: 2051-2061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway2011
- Author(s)
  Toyokawa G, Cho HS, Masuda K, Yamane Y, Yoshimatsu M, Hayami S, Takawa M, Iwai Y, Daigo Y, Tsuchiya E, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  Neoplasia
  
  Volume: 13 Pages: 887-898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers2011
- Author(s)
  Hayami S, Kelly JD, Cho HS, Yoshimatsu M, Unoki M, Tsunoda T, Field HI, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  International Journal of Cancer
  
  Volume: 128 Pages: 574-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers2011
- Author(s)
  Yoshimatsu M, Toyokawa G, Hayami S, Unoki M, Tsunoda T, Field HI, Kelly JD, Neal DE, Maehara Y, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  International Journal of Cancer
  
  Volume: 128 Pages: 562-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH12011
- Author(s)
  Cho HS, Kelly JD, Hayami S, Toyokawa G, Takawa M, Yoshimatsu M, Tsunoda T, Field HI, Neal DE, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  Neoplasia
  
  Volume: 13 Pages: 676-684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis : involvement in the proliferation of cancer cells through the E2F/RB pathway2010
- Author(s)
  Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R
- Journal Title
  
  Molecular Cancer
  
  Volume: 13 Pages: 59-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] UHRF1 is a novel diagnostic marker of lung cancer.2010
- Author(s)
  Unoki M, Daigo Y, Koinuma J, Tsuchiya E, Hamamoto R, Nakamura Y
- Journal Title
  
  British Journal of Cancer
  
  Volume: 103 Pages: 217-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells2010
- Author(s)
  Kashiwaya K, Nakagawa H, Hosokawa M, Mochizuki Y, Ueda K, Piao L, Chung S, Hamamoto R, Eguchi H, Ohigashi H, Ishikawa O, Janke C, Shinomura Y, Nakamura Y
- Journal Title
  
  Cancer Research
  
  Volume: 70 Pages: 4024-4033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22681030
[Journal Article] Enhanced expression of RAD51AP1 is involved in the growth of intrahepatic choloangiocarcinoma cells.2008
- Author(s)
  Obama K, Satoh S, Hamamoto R, Sakai Y, Nakamura Y, Furukawa Y.
- Journal Title
  
  Clinical Cancer Research 14(5)
  
  Pages: 1333-1339
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells2008
- Author(s)
  Silva FP, Hamamoto R, Kunizaki M, Tsuge M, Nakamura Y, Furukawa Y
- Journal Title
  
  Oncogene 27
  
  Pages: 2686-2692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced expression of RAD51AP1 is involved in the growth of intrahepatic choloangiocarcinoma cells2008
- Author(s)
  Obama K, Satoh S, Hamamoto R, Sakai Y, Nakamura Y, Furukawa Y
- Journal Title
  
  Clin. Cancer Res 14
  
  Pages: 1333-1339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] The lysine 831 of VEGFR1 is a novel target of methylation by SMYD3.2007
- Author(s)
  Kunisaki M, Hamamoto R, Silva FP, Yamaguchi K, Nagayasu T, Shibuya M, Nakamura Y, Furukawa Y.
- Journal Title
  
  Cancer Res 67(22)
  
  Pages: 10759-10765
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced SMYD3 expression is essential for the growth of breast cancer cells.2006
- Author(s)
  Hamamoto, R., et al.
- Journal Title
  
  Cancer Science 97
  
  Pages: 113-118
- NAID
  10020388459
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] VNTR Polymorphism of E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.2005
- Author(s)
  Tsuge M, Hamamoto R, Silva FP, Ohnishi Y, Chayama K, Kamatani N, Furukawa Y, Nakamura Y.
- Journal Title
  
  Nature Genet 37(10)
  
  Pages: 1104-1107
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] アノテーション支援装置、アノテーション支援方法及びアノテーション支援プログラム2019
- Inventor(s)
  小林和馬、三宅基隆、浜本隆二
- Industrial Property Rights Holder
  小林和馬、三宅基隆、浜本隆二
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-010287
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03429
[Patent] アノテーション支援装置、アノテーション支援方法及びアノテーション支援プログラム2019
- Inventor(s)
  小林和馬、三宅基隆、浜本隆二
- Industrial Property Rights Holder
  小林和馬、三宅基隆、浜本隆二
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-010287
- Filing Date
  2019
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Patent] METHODS OF MODULATING SMYD3 FOR TREATMENT OF CANCER2005
- Inventor(s)
  中村祐輔, 古川洋一, 浜本降二, 中鶴修一
- Industrial Property Rights Holder
  国立大学法人東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-07-01
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] METHODS OF MODULATING SMYD3 FOR TREATMENT OF CANCER2005
- Inventor(s)
  中村祐輔、古川洋一、中鶴修一、浜本隆二
- Industrial Property Rights Holder
  オンコセラピーサイエンス社
- Filing Date
  2005-07-01
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] AIを活用した日本人肺がんの統合的マルチオミックス解析2023
- Author(s)
  浅田健、浜本隆二
- Organizer
  第27回日本がん分子標的治療学会学術集会、口頭発表 (2023.6.23 佐賀)
- Invited
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Identificationand implication of nuclear-mitochondria segments (NUMTs) in lung adenocarcinoma development2023
- Author(s)
  Amina Bolatkan, Ken Asada, Syuzo Kaneko, Masaaki Komatsu, Ryuji Hamamoto
- Organizer
  第82回日本癌学会学術総会、ポスター発表（英語） (2023.9.21 Yokohama)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] アンメットニーズ克服に向けた肺がんpan-negative症例におけるマルチオミックス解析2023
- Author(s)
  浅田健、ボラトカンアミナ、浜本隆二
- Organizer
  第5回日本メディカルAI学会学術集会、口頭発表 (2023.6.18 東京)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] 解析対象サンプル群のマルチオミックス情報及び転写因子公共情報に基づいたがん関連スーパーエンハンサー評価プラットフォームの構築2023
- Author(s)
  新海典夫、金子修三、浅田健、高澤建、小松正明、浜本隆二
- Organizer
  第5回日本メディカルAI学会学術集会、口頭発表 (2023.6.18 東京)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Multi-omics analysis revealed novel fusion genes and NUMTs in lung cancer2023
- Author(s)
  ボラトカンアミナ、浅田健、金子修三、小松正明、浜本隆二
- Organizer
  第5回日本メディカルAI学会学術集会、ポスター発表 (2023.6.17 東京)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Integrated multi-omics analysis using WGS, ChIP-seq, and RNA-seq data for pan-negative lung adenocarcinoma2023
- Author(s)
  Ken Asada, Syuzo Kaneko, Ken Takasawa, Kouya Shiraishi, Hidehito Horinouchi, Yukihide Yoshida, Masami Mukai, Norio Shinkai, Yasushi Yatabe, Takashi Kohno, Ryuji Hamamoto
- Organizer
  第82回日本癌学会学術総会、インターナショナルセッション口頭発表（英語） (2023.9.21 Yokohama)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] マルチオミックス情報及び公共転写因子情報による機械学習を活用したがん関連スーパーエンハンサー評価実施プラットフォーム2023
- Author(s)
  新海典夫、金子修三、浅田健、高澤建、小松正明、町野英徳、浜本隆二
- Organizer
  第82回日本癌学会学術総会、口頭発表（日本語） (2023.9.21 Yokohama)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Tumor suppressive role of the PRELP gene in ovarian clear cell carcinoma2023
- Author(s)
  小松正明、金子修三、青山利奈、新海典夫、町野英徳、浅田健、吉田裕、加藤友康、浜本隆二
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03429
[Presentation] Cancer-related super-enhancer evaluation system using TFs and gene expression data from public ChIP-seq and RNA-seq data2022
- Author(s)
  Norio Shinkai, Syuzo Kaneko, Ken Asada, Ken Takasawa, Masaaki Komatus, Ryuji Hamamoto
- Organizer
  第81回日本癌学会、ポスター発表（日本語） (2022.9.29 Yokohama)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] 肺がんPan-negative症例のゲノム・エピゲノム・トランスクリプトーム情報を含めたマルチオミックス解析2022
- Author(s)
  浅田健、新海典夫、金子修三、高澤建、浜本隆二
- Organizer
  第4回日本メディカルAI学会学術集会、口頭発表 (2022.6.10 仙台)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Multi-omics analysis using machine learning and implication for cancer studies2022
- Author(s)
  Ken Asada, Syuzo Kaneko, Ken Takasawa, Kouya Shiraishi, Hidehito Horinouchi, Yukihide Yoshida, Masami Mukai, Norio Shinkai, Yasushi Yatabe, Takashi Kohno, Ryuji Hamamoto
- Organizer
  第81回日本癌学会、口頭発表（英語） (2022.9.29 Yokohama)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] 公共ChIP-seqデータセットによるoncogenic TF解析情報を用いたスーパーエンハンサー評価システムの構築2022
- Author(s)
  新海典夫、金子修三、浅田健、高澤建、小松正明、浜本隆二
- Organizer
  第4回日本メディカルAI学会学術集会、口頭発表 (2022.6.10 仙台)
- Data Source
  KAKENHI-PROJECT-22K07180
[Presentation] Integrative analysis revealed early epigenetic changes in high-grade serous ovarian carcinogenesis2021
- Author(s)
  Hidenori Machino, Ai Dozen, Masaaki Komatsu, Kohei Nakamura, Kanto Shozu, Syuzo Kaneko, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Kentaro Nakayama, Satoru Kyo, Ryuji Hamamoto
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Epigenetic and functional analyses of PRELP gene in ovarian cancer2021
- Author(s)
  Masaaki Komatsu, Ai Dozen, Kanto Shozu, Syuzo Kaneko, Hidenori Machino, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Ryuji Hamamoto
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] ヒストン脱アセチル化酵素阻害剤は膀胱癌においてH2BK5のアセチル化を促進することによりPRELPの発現を増加させる2021
- Author(s)
  生水貫人、金子修三、浅田健、同前愛、町野英徳、高澤建、中島彰俊、小松正明、浜本隆二
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03429
[Presentation] LKB1-MARK3 axis is a novel stress-activated cell cycle checkpoint and dysregulated in high-grade serous ovarian cancer.2020
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Ken Asada, Ai Dozen, Kanto Shozu, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Integrative multi-omics analysis of multistage carcinogenesis in high-grade serous ovarian cancer.2020
- Author(s)
  Ai Dozen, Masaaki Komatsu, Hidenori Machino, Kohei Nakamura, Syuzo Kaneko, Kanto Shozu, Ken Asada, Tatsuaki Chiyoda, Kentaro Nakayama, Daisuke Aoki, Satoru Kyo, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Clinical epigenetic analysis with robotics in ovarian cancer.2020
- Author(s)
  Masaaki Komatsu, Syuzo Kaneko, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] 臨床のリアル・ワールド・データを利用した人工知能技術の開発を加速するための統合的なデータ・プラットフォームの構築2020
- Author(s)
  小林和馬、三宅基隆、渡辺裕一、浜本隆二
- Organizer
  第2回日本メディカルAI学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] Novel clinical epigenetics using robotics toward precision medicine in ovarian cancer.2020
- Author(s)
  Masaaki Komatsu, Ai Dozen, Kanto Shozu, Hidenori Machino, Tomoyasu Kato, Ryuji Hamamoto.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] 肺がん予後予測を施行したマルチオミックス解析2020
- Author(s)
  浅田健、小林和馬、高橋慧、高澤建、小松正明、金子修三、浜本隆二
- Organizer
  第2回日本メディカルAI学会学術集会
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] Biological mechanisms of PRELP in ovarian cancer.2020
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Ken Asada, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] 卵巣癌におけるPRELPの機能解析2020
- Author(s)
  生水　貫人、小松　正明、金子　修三、同前　愛、町野　英徳、中島　彰俊、齋藤　滋、浅田　健、浜本　隆二
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03429
[Presentation] WNT7A gene was regulated by epigenetic changes and associated with tumorigenesis in ovarian clear cell carcinoma.2020
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Tomoyasu Kato, Ryuji Hamamoto.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Development of the Integrated Medical System Using Artificial Intelligence: Towards the Realization of Precision Medicine2019
- Author(s)
  浜本　隆二
- Organizer
  第83回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] Epigenetic regulation of the WNT7A gene in ovarian clear cell carcinoma2019
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Tumor suppressive roles of MARK3 in high-grade serous ovarian carcinomas2019
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Ai Dozen, Kanto Shozu, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Epigenetic regulation of epithelial cell integrity through extracellular matrix in ovarian cancer2019
- Author(s)
  Ai Dozen, Masaaki Komatsu, Syuzo Kaneko, Kanto Shozu, Hidenori Machino, Tatsuyuki Chiyoda, Daisuke Aoki, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Clinical epigenetics using artificial intelligence and robotics in ovarian cancer2019
- Author(s)
  Masaaki Komatsu, Syuzo Kaneko, Ken Asada, Tomoyasu Kato, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] 解釈可能な特徴抽出を可能にする深層学習モデルによる肺がん病理型の予測2019
- Author(s)
  小林和馬、Amina Bolatkan、新海典夫、浜本隆二
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 臨床応用を志向したメディカルAI研究～Precision Medicine時代における医療ビッグデータ解析～2019
- Author(s)
  浜本　隆二
- Organizer
  日本オミックス医学会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 臨床応用を志向した人工知能技術を活用した医療システムの開発2018
- Author(s)
  浜本　隆二
- Organizer
  日本産科婦人科遺伝診療学会・第４回学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 臨床応用を志向したChIP-seq技術に基づいたがんエピゲノム解析の開発2018
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  The 1st Annual Meeting of the Japanese Association for Medical Artificial Intelligence
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] 臨床応用を志向した人工知能技術を用いた統合的ながん医療システムの開発2018
- Author(s)
  浜本　隆二
- Organizer
  第19回日本分子脳神経外科学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 人工知能技術を活用した医療オミックスデータの解析及び診断・治療への応用2018
- Author(s)
  浜本　隆二
- Organizer
  GTC Japan 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] Development of the integrated cancer medical system using artificial intelligence2018
- Author(s)
  浜本　隆二
- Organizer
  THE 12th SUGIYAMA LABORATORY (RIKEN) OPEN SYMPOSIUM
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 人工知能技術を用いたがんの本態解明及び診断・治療への応用2018
- Author(s)
  浜本　隆二
- Organizer
  第38回日本分子腫瘍マーカー研究会・シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] AI技術を活用した統合的ながん医療システムの開発2018
- Author(s)
  浜本　隆二
- Organizer
  CBI学会2018年大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] 人工知能技術のがん医療への応用：がんゲノム医療時代のオミックス解析2018
- Author(s)
  浜本　隆二
- Organizer
  第56回日本癌治療学会学術集会・学術セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] Toward precision medicine: developing new toolbox to study the epigenetics applied for cancer treatment2018
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Development of the integrated cancer medical system using artificial intelligence: Towards the realization of Precision Medicine2018
- Author(s)
  浜本　隆二
- Organizer
  6th US-Japan Clinical Trials in Oncology Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04908
[Presentation] RBI methylation by SMYD2 enhances cell cycle progression through an increase of RBI phosphorylation2012
- Author(s)
  Shinya Hayami, Hyun-Soo Cho, Hiroki Yamaue, Yusuke Nakamura, Ryuii Hamamoto
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22681030
[Presentation] A Project Developing a New Cancer Therapy Targeting Histone Methyltransferase and Demethylase.2010
- Author(s)
  Ryuji Hamamoto
- Organizer
  日本癌学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-22681030
[]
[]
[]

1. Kaneko Syuzo (10777006)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. 浅田健 (70773414)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
3. FURUKAWA Yoichi (20272560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. OSADA Hiroyuki (80160836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SIMIZU Siro (30312268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. USUI Takeo (60281648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAKEYA Hideaki (00270596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SEKIYAMA Yasuyo (60342804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MACHIDA Kiyotaka (30332266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Komatsu Masaaki (70750842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
11. 境倫宏 (10448681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 亀井政孝 (60443503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 島岡要 (40281133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 元井紀子 (70292878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 石井源一郎 (00270869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉田達哉 (10729338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大江裕一郎 (20233041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 田丸淳一 (30188429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 白澤昌之 (40898996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 青木一教 (60270675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 吉田裕 (70750751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 河野隆志 (80280783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 渡辺俊一 (80303303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 神田浩明 (90260067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KAWAI Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 醍醐弥太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 角田達彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 北條秀博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 秋元哲夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 山田裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 高橋慧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 松本光司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 山上裕機

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 速水晋也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 澤井照光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 町野英徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 砂金秀章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hamamoto Ryuji 浜本 隆二

HAMAMOTO Ryuji 浜本 隆二

浜本 隆二 ハマモト リュウジ

Research Projects

Research Products

Co-Researchers

エンハンサー領域に着目した肺がんpan-negative症例の統合オミックス解析

Principal Investigator

Project Period (FY)

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Review Section

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Development study on pathological predictive biomarkers for cancer treatment

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Next generation epigenomics using artificial intelligence and robotics in ovarian cancer

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Integrated functional analysis of the novel tumor suppressor genes OMD and PRELP, and their application to treatment of cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

敗血症患者における血小板内環状RNAの解析

Principal Investigator

Project Period (FY)

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Research Institution

Construction of a multilayered integrated epigenetics database based on machine learning and deep learning

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

がんの統合的解明を目指した生体情報の階層的ネットワーク構造に対する深層学習の応用Principal Investigator

Principal Investigator

Project Period (FY)

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タンパク質メチル化を標的とした新規がんの分子標的治療薬の開発Principal Investigator

Principal Investigator

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Research Institution

Development of new diagnostic and therapeutic approaches based on information of the human genome

Principal Investigator

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バイオ人工肝臓構築を目指した、低分子薬剤による株化肝細胞の分化誘導システムの構築Principal Investigator

Principal Investigator

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Chemical biology study on protein phosphatases and their specific inhibitors.

Principal Investigator

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Research Institution

[Book] 実験医学2019年10月号2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] iｎ ｓｉｌｉｃｏ創薬におけるスクリーニングの高速化・高精度化技術2018

Author(s)

Total Pages

Hamamoto Ryuji 浜本隆二

HAMAMOTO Ryuji 浜本隆二

浜本隆二ハマモトリュウジ

[Book] iｎｓｉｌｉｃｏ創薬におけるスクリーニングの高速化・高精度化技術2018