• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

takahashi naoyuki  高橋 直之

ORCIDConnect your ORCID iD *help
… Alternative Names

TAKAHASHI Naoyuki  高橋 直之

Less
Researcher Number 90119222
Other IDs
Affiliation (Current) 2025: 松本歯科大学, 総合歯科医学研究所, 特任教授
Affiliation (based on the past Project Information) *help 2016 – 2020: 松本歯科大学, 総合歯科医学研究所, 特任教授
2010 – 2016: 松本歯科大学, 総合歯科医学研究所, 教授
2007 – 2010: Matsumoto Dental University, Graduate School for Dentistry, Professor
2008: 松本歯科大学, 大学院歯学独立研究科, 教授
2005 – 2006: 松本歯科大学, 大学院歯学独立研究科, 教授 … More
2004 – 2005: Matsumoto Dental University, Institute for Dental Science, Professor, 総合歯科医学研究所, 教授
2003 – 2005: Matsumoto Dental University, Graduate School of Oral Medicine, Hard Tissue Research, Professor, 大学院・歯学独立研究科, 教授
2003: 松本歯科大学, 総合歯科・医学研究所, 教授
2001 – 2002: Institute for Dental Science, Professor, 総合歯科医学研究所, 教授
2001: 松本歯科大学, 総合歯科医学研究所・機能解析学, 教授
2000: 昭和大, 歯学部, 助教授
1991 – 2000: Showa Univ., School of Dentistry Associate Professor, 歯学部, 助教授
1997: Showa University, School of Dentistry, Associate Professor, 歯学部, 教授
1987 – 1990: School of Dentistry, Showa University, 歯学部, 講師
1989: 昭和大学, 歯学部・生化学教室, 講師 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry / General medical chemistry / Biological Sciences
Except Principal Investigator
Functional basic dentistry / Orthodontic/Pediatric dentistry / Functional basic dentistry / Morphological basic dentistry / Morphological basic dentistry / Surgical dentistry … More / Orthodontics/Pediatric dentistry / Basic Section 57010:Oral biological science-related / Dental engineering/Regenerative dentistry / Biomedical engineering/Biological material science Less
Keywords
Principal Investigator
破骨細胞 / 骨芽細胞 / RANKL / OPG / M-CSF / IL-1 / osteoclast / Smad / BMP / マクロファージ … More / MyD88 / リポ多糖 / osteoblast / Osteoblast / 骨吸収 / Nod2 / RANK / ODF / カルシトニン / p60^<c-src> / Osteoclast / 骨代謝共役 / Wnt / 破骨細胞前駆細胞 / シグナル伝達 / 炎症性サイトカイン / ムラミルジペプチド / 骨髄マクロファージ / TRIF / ビスフォスホネート / Lipopolysaccharide / Osteoclasts / 骨誘導因子 / IL-11 / IL-6 / gp130 / 波状縁 / c-src / ocマウス / oc / opマウス / op / 大理石骨病 / MーCSF / Wntシグナル / Wnt非古典経路 / Wnt5a / 破骨細胞ニッチ / Wnt / 口腔生化学 / 異所性骨形成 / 可溶性RANKL / カルシウム / p38MAPキナーゼ / p38MAPK / 骨形成 / ビスフォスフォネート / 破骨細胞活性化因子 / HtrA1 / LIF / スクレロスチン / クラストカイン / カップリング因子 / Fos deficient mice / Osteoclast niche / Cell cycle-arrested quiescent osteoclast precursor / Osteoblasts / プロモデオキシウリジン / RANK-Cre / 骨髄細胞マクロファージ / Fos欠損マウス / 細胞周期停止破骨前駆細胞 / Bone morphogenetic protein / Prostaglandin E_2 / Muramyl dipeptide / inflammatory bone resorption / Toll様受容体 / ペプチドグリカン / 小動物用X線CT / Nod / 骨誘導因子(BMP) / プロスタグランジンE_2 / ムラミルジペプチド(MDP) / リポ多糖(LPS) / 炎症性骨吸収 / PGE_2 receptor / Muramyl dipeptide (MDP) / Lipopolysaccharide (LPS) / 樹状細胞 / インターロイキン1 / PGE_2受容体 / ectonic bone formation / soluble RANKL / Coupling / Bisphosphonate / Receptor activator of NF-κB (RANKL) / Osteoprotegerin (OPG) / サイトカイン / 骨代謝共役因子 / アルカリフォスファターゼ / オステオプロテゲリン / 骨髄間質細胞 / ERK / p38 MAP kinase / Inflammatory cytokine / Macrophage / Osteoporosis / Calcium / Inflammatory cytokines / 細胞内Ca / TNFα / 骨粗鬆症 / osteoclast activiting factor / osteoclastogenesis inhibitory factor(OCIF) / osteoprotegerin(OPG) / 破骨細胞分化因子(ODF) / 1L-1 / NF-kB / signal transduction / bone resorbing factors / bone morphogenetic protein / myoblast / ビスホスフォネート / BMPレセプター / p130^<Cas> / NF-κB / 筋芽細胞 / rheumatoid arthritis / bone resorption / osteoblasts / osteoclasts / IL-6 receptor / 滑液 / トランスジェニックマウス / 可溶性IL-6レセプター / 慢性関節リウマチ / IL-6レセプター / small GTP binding protein rho / PI-3 kinase / calcitonin / podosme / clear zone / ruffled border / 吸収窩 / ポドソーム形成 / Focal adhesion kinase / Pl-3キナーゼ / 低分子量G蛋白rho / PI-3キナーゼ / ポドソーム / 明帯 / 1alpha,25(OH)_2D_3 / macrophage colony stimulating (M-CSF) / osteopetrosis / 活性型ビタミンD / マクロファ-ジコロニ-剌激因子 / cell-cell interaction / osteopetosis / 1alpha, 25 (OH) _2D_3 / macrophage / monocyte / 骨髄由来ストロ-マ細胞 / 骨吸収調節因子 / マクロファ-ジコロニ-刺激因子 / 1α,25(OH)_2D_3 / マクロファ-ジ / QOP / Sclerostin / OPG / RANKL / エピタキシー因子 / チタン / 石灰化 / カーボンナノチューブ / Rho / 低分子量Gタンパク質 / Wnt5a-Ror2シグナル / 波上縁 / 極性化 / Ror2 / IL-34 / 活性型ビタミンD_3 / 破骨細胞分化阻止因子(ODIF) / 石灰化硬組織 / 80陽性マクロファージ / F4 / 異所性骨化 / OPG欠損マウス / 破骨細胞分化阻止因子ODIF / PKC / 3細胞 / SaOS-4 / 骨粗鬆症治療薬 / RAW264細胞 / 破骨細胞形成抑制因子 / TAK1 / ヒトCD14陽性細胞 / PGE_2 … More
Except Principal Investigator
破骨細胞 / 骨芽細胞 / 骨吸収 / RANKL / 活性型ビタミンD / OPG / BMP / osteoclast / bone resorption / M-CSF / osteoblast / Osteoclast / 骨形成 / 副甲状腺ホルモン / 骨粗鬆症 / カルシトニン / Bone resorption / 骨細胞 / マクロファージ / RANK / osteoporosis / 骨誘導因子 / Osteoblast / 破骨細胞前駆細胞 / op / EP4 / 細胞分化 / MyD88 / リポ多糖 / オステオプロテゲリン / ODF / IL-1 / エストロゲン / 筋芽細胞 / カルシウム / GM-CSF / 細胞融合 / マクロファ-ジ / ビタミンD / 骨代謝回転 / Wnt5a / オステオポンチン / PTH / 骨改造 / Cre recombinase / EP2 / PGE_2 / 歯周病 / Ca^<2+> / lipopolysaccharide / 炎症性サイトカイン / 歯周疾患 / H-ATPase / in vivo / in vitro / Fas / EP4 agonist / Toll-like receptor / TNF / OCIF / 遺伝子欠損マウス / 受容体 / NF-κB / エストロゲン受容体 / IL-7 / Smad / 骨代謝 / インターロイキン-7 / hemopoiesis / estrogen / アンドロゲン / Bリンパ球 / 骨髄造血 / インターロイキン1 / myoblast / Hedgehog / bone marrow / bisphosphonates / 波状縁 / ビスフォスフォネート / gp130 / 骨 / インターロイキン6 / 腎臓 / Osteoclasts / 1alpha, 25-Dihydroxyvitamin D_3 / ポリアミン / カルシウム吸収 / 補体第3因子 / 1alpha, 25(OH)_2D_3 / マクロファ-ジコロニ-刺激因子 / 骨吸収因子 / LIF / ヒスタチン / 歯槽骨 / Wnt / 加齢 / 転写因子 / NFATc1 / OPG遺伝子欠損マウス / 免疫組織化学 / カップリングファクター / アルカリフォスファターゼ / ヒト破骨細胞 / 細胞老化 / Sfrp5 / Wnt5a / Pkn3 / 骨量 / Sfrp5 / スクレロスチン / 脂肪細胞 / Transglutaminase / Spermidine / Calcium / Cell Fusion / Macrophage / トランスグルタミナ-ゼ / スペルミジン / 1,25(OH)_2D_3 / collagenase / コラゲナーゼ / コラゲナ-ゼ / osteoblasts / macrophage fusion factor (MFF) / differentiation-inducing factor (DIF) / 1alpha,25-dihydroxyvitamin D_3 [1alpha,25(OH)_2D_3 / コロニー形成因子(CSF) / 骨髄細胞 / マクロファージ融合因子(MFF) / マクロファージ融合因子 / 活性型ビタミンD_3(1α,25(OH)_2D_3) / 分化誘導因子(DIF) / Cell-fusion / Macrophages / Vitamin D / 多核巨細胞 / マクロファージの融合 / 骨吸収活性 / MGBG / LPS / DIF / OAF / トリグリセライド / 融合 / 肺胞マクロファージ / 分化誘導因子 / osteoclast precursors / orthodontics / 相同組み換え / BACクローン / COX2 / ノックインマウス / 歯周組織 / Creリコンビナーゼ / Osteoclast progenitors / CD14-positive cells / Human osteoclasts / Albeolar bone resorption / ビスフォスホネート / リゼドロネート / opマウス / CD14陽性細胞 / 歯槽骨吸収 / osteoclasts / peptidoglycan / Nod2 / ペプチドグリカン / bone metabolomics / pathology / oral histology / cell・tissue / gene / 電子顕微鏡 / 細胞培養 / 骨代謝学 / 病理学 / 歯学 / 細胞・組織 / 遺伝子 / heat shock proteins / histatins / human gingival fibroblast (HGF) / periodontitis / 熱ショックタンパク質 / 細胞増殖 / 歯肉線維芽細胞 / 熱ショック蛋白質 / 歯肉線維芽細胞(HGF) / Lysosome / Vacuole / Transcytosis / Transportation in cell / Endocytosis / Bone matrix / Ca^<+2> / lysosome / vacuole / transcytosis / 細胞内輸送 / endocytosis / 骨基質 / coupling factor / bone formation / 共役機構 / 象牙芽細胞 / 骨代謝共役因子 / inflammatory cytokine / muramyldipeptide / periodontal disease / ムラミルジペプチド / Toll様受容体 / 菌体成分 / cathepsin K / カテプシンK / tamoxifen / estrogen receptor / bone remodeling / apotosis / mechanical stress / osteocyte / p38 MAPK / RAW264.7 / PGE_2受容体 / プロスタグランジンE_2 / 機械的刺激 / タモキシフェン / 骨リモデリング / 細胞死 / 機械刺激 / Laser / Dental pulp / Coupling factor / Bone formation / Calcification / 急速凍結法 / レーザー / プロスタグランジンE2 / カップリング因子 / 石灰化 / CELL DIFFERENTIATION / MYOBLAST / OSTEOBLAST / BONE MORPHOGENETIC PROTEIN / GROWTH FACTOR / HORMONE / TRANSCRIPTION FACTOR / BONE FORMATION / 血清 / 転写調節因子 / 成長因子 / ホルモン / Lipopeptide / Lipopolysaccharide / 骨代謝共役 / 1α, 25(OH)_2D_3 / マクロファジーコロニー刺激因子 / 骨随間質細胞 / 破骨細胞形成抑制因子 / 破骨細胞分化因子 / 1α-hydroxylase / 1α,25-dihydroxyvitamin D3 / parathyroid hormone / ステロイドホルモン / 1α-水酸化酵素 / Gene targetting mouse / T-lymphocyte / Interferon gamma / Interleukin 18 / Tリンパ球 / インターフェロンγ / インターロイキン18 / Estrogen / IL-6 / PHT受容体 / シグナル伝達 / TNFファミリー / 破骨細胞分化因子(ODF) / 卵巣摘出術 / 骨誘導因子(BMP) / bone mineral density / ovariectomy / interleukin-7 / B cells / 骨髄 / 骨密度 / 卵巣摘出 / interleukin-6 / interleukin-1 / androgen / プロスタグランジン / chondrocyte / ostepblast / 筋肉 / 骨形成因子(BMP) / 間葉系細胞 / 骨髄間質細胞 / 軟骨細胞 / bone / macrophage / vitamin D / stromal cells / complement 3 / C3遺伝子 / 補体第3因子(C3) / ビタミンD欠乏 / 骨髄ストローマ細胞 / 転写調節 / calcitonin / pit formation / osteoclast function / osteoclast formation / screening system / 吸収窩 / ポドソーム形成 / 骨吸収評価系 / 骨吸収試験 / アクチンリング形成 / ポドソーム / 明帯 / チロシンフォスファーゼ / ビイフォスフォネート / cAMP / アクチンリング / 破骨細胞機能評価系 / 破骨細胞形成評価系 / スクリーニング系 / interleukin 11 / interleukin 6 / calcium absorption / 24,25(OH)_2D_3 / 1α,25(OH)_2D_3 / ビタミンDレセプター / インターロイキン11 / 小腸 / 肝臓 / 抗クル病因子 / Growth factor / Bone resorbing agents / the third component of complement (C3) / Calcium pump / Osteoblasts / Intestine epithelial cells / 小腸上皮細胞細胞 / 増殖因子 / カルシウムポンプ / 小腸の吸収上皮細胞 / Macrophage colony stimulating factor / Bone resorbing factors / 骨髄由来ストロ-マ細胞 / 骨吸収調節因子 / マウス骨髄細胞培養 / MーCSF / retinoic acid / cell line / differentiation / 骨肉腫 / レチノイン酸 / 培養細胞 / 分化 / Lalpha, 25 (OH) _2D_3 / Macrophage fusion / Interleukin 1 / Osteopontin / Iγ-6 / Iγ-4 / GMーCSF / インタ-ロイキン1 / ILー6 / 質量分析 / 天然化合物 / リン酸化 / 唾液蛋白質 / 抗がん剤 / 抗癌剤 / 天然有機化合物 / コンディショナルノックアウト / 歯の移動 / 骨芽細胞特異的遺伝子欠損 / 歯科矯正学 / エピジェネティック解析 / 破骨細胞前駆(QuOPs) / 破骨細胞前駆細胞(QuOPs) / エピタキシー / カーボンナノチューブ / MAPキナーゼ / ヒト歯根膜 / 破骨細胞形成阻止因子 / ヒトCD14陽性細胞 / ヒト末梢血 / 歯根膜細胞 / OPG欠損マウス / 微細形態 / エナメル芽細胞前駆細胞 / 象牙芽細胞前駆細胞 / 骨芽細胞前駆細胞 / 間葉系幹細胞 / 象牙質シアロタンパク質 / 移植 / 器官培養 / 歯の再生 / 歯髄 / 歯胚 / ヒト抹消血 / 共存培養 / ヒト抹消血単核細胞 / PTHレセプター / 破骨細胞分子因子(ODF) / SaOS-2 Less
  • Research Projects

    (67 results)
  • Research Products

    (219 results)
  • Co-Researchers

    (75 People)
  •  Does aging of osteocytes adversely affect bone metabolism?

    • Principal Investigator
      yamashita teruhito
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Matsumoto Dental University
  •  Development of alveolar bone turnover control method based on Wnt signaling network

    • Principal Investigator
      Kobayashi Yasuhiro
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the osteoclast-derived cytokine-Wnt signaling network responsible for coupling between bone resorption and formation.Principal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Matsumoto Dental University
  •  Investigation of factors determining terminal differentiation into osteocytes

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  How is the formation site of osteoclasts determined?Principal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of Wnt signaling network controlling bone metabolismPrincipal Investigator

    • Principal Investigator
      Takahashi Naoyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  骨代謝共役を担うWntシグナルの解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Development of alveolar bone turnover control method based on Wnt5a

    • Principal Investigator
      Kobayashi Yasuhiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Novel mechanism of regulating the activity of the transcription factor NFATc1 in bone metabolism

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Do carbon nanotubes control bone remodeling?Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the mechanism of action in salivary protein histatin aimed at soft tissue injury treatment and regenerative medicine

    • Principal Investigator
      IMAMURA Yasuhiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of osteoclast niche regulated by Wnt signals.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Role of Wnt-Ror2 signals in ruffled border formation in osteoclastsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of roles of Wnt5a in alveolar bone remodeling, and their application for orthodontic tooth movement.

    • Principal Investigator
      KOBAYASHI Yasuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of the novel inhibitory mechanism of anti-tumor drug arctigenin on bone resorption

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of molecular mechanism of carbon nanotube regulating bone metabolism

    • Principal Investigator
      MIZOGUCHI Toshihide
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Matsumoto Dental University
  •  Analysis of novel MAP kinase binding factor which regulates osteoclasts

    • Principal Investigator
      YAMASHITA Teruhito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  The relationship between cell proliferation and RANKL-induced osteoclastogenesisPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Application of Cre-loxP system for elucidation of mechanisms in bone remodeling during tooth movement

    • Principal Investigator
      KOBAYASHI Yasuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Effects of osteoprotegerin administration on osteoclast differentiation and trabecular bone structure in osteoprotegerin-deficient mice.

    • Principal Investigator
      MAYAHARA Mitsuori, 佐々木 崇寿
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Analysis of the Nod signals which enhance bone resorption

    • Principal Investigator
      YANG Shufa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of molecular mechanism of alveolar bone remodeling induced by orthodontic force.

    • Principal Investigator
      KURIHARA Saburo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  再生骨および歯と受容者(recipient)組織間の特異的相互作用の解析

    • Principal Investigator
      小澤 英浩
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  歯根膜組織に存在する歯根吸収を抑制する新規因子の探索

    • Principal Investigator
      二宮 禎
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Study on the molecular mechanism of alveolus bone resorption induced periodontal diseasesPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Ca^<2+> kinetics in mature osteoclast

    • Principal Investigator
      YAMAKI Mariko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Elucidation of receptors for salivary protein histatin in human gingival fibroblast

    • Principal Investigator
      IMAMURA Yasuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  破骨細胞分化阻止因子(ODIF)のクローニングと生理的役割の解析Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  The establishment of inducible osteocyte ablation mouse model to elucidate the mechanisms of maxillo-mandibular dysmorphia.

    • Principal Investigator
      HOSOYA Akihiro, 小林 泰浩
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Establishment of Bone Metabolism Research through Regulation of Osteoclast Differentiation and Functions

    • Principal Investigator
      SASAKI Takahisa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  The possible mechanism of alveolar bone destruction induced by constituent of gram-negative bacteria.

    • Principal Investigator
      SHUHUA Yang
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of tooth development of osteoprotegerin- deficient mice

    • Principal Investigator
      NAKAMURA Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Matsumoto Dental University
  •  Analysis of molecular mechanisms in bone formation and regeneration

    • Principal Investigator
      OZAWA Hidehiro
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Signal transduction and cell-to-cell communication in the bone resorption induced by inflammationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  骨芽細胞及びリンパ球の分化を促進する破骨細胞由来新規サイトカインの同定

    • Principal Investigator
      宇田川 信之
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
      Showa University
  •  Analysis of signal transduction of osteoclast differentiation factor (RANKL) in alveolar bone destruction

    • Principal Investigator
      UDAGAWA Nobuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  Study on mechanism of the coupling between bone resorption and bone formationPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Matsumoto Dental University
  •  CHARACTERIZATION OF THE BONE FORMING FACTORS IN SERUM

    • Principal Investigator
      KATAGIRI Takenobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      SHOWA UNIVERSITY
  •  破骨細胞を調節するシグナル伝達系と骨・歯周疾患における骨破壊機序の解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Matsumoto Dental University
      Showa University
  •  Analysis of signal transduction of inflammatory cytokines in bone destructionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      MATSUMOTO DENTAL UNIVERSITY
      Showa University
  •  破骨細胞の融合機構とその生理的意義の解明Principal Investigator

    • Principal Investigator
      高橋 直之
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The physiological role of osteoclast differentiation factor.

    • Principal Investigator
      UDAGAWA Nobuyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on signal transduction in osteoclastogenesis for the development of anti-osteoporosis drugs.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The roles of nuclear transcription factors in calcium homeostasis

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on osteoclast activiting factor expressed by osteoblasts/stromal cellsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Mechanism of osteoclastogenesis inhibitory action by interleukin 18

    • Principal Investigator
      UDAGAWA Nobuyuki, 宇田川 信之
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of bone metabolism improvement medicines based on the analysis of signal transduction

    • Principal Investigator
      SUDA Tasuo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Analysis of gp130-induced signals which regulate osteclast formation and functionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Establishment of assay systems for examining bone metabolism : Studies on differentiation and function of osteoblasts and osteoclastsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Role of BMPs in differentiation process of osteoblasts, chondrocytes and muscle cells

    • Principal Investigator
      YOSHIKI Susaku
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Molecular mechanisms of osteoporosis induced by estrogen deficiency.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Analysis of signaling pathways involved in polarization of osteoclasts.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of reliable screening systems for drugs which regulate bone resorption : In vitro assay systems for osteoclast formation and function.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Production and biological roles of the third component of complement in bone.

    • Principal Investigator
      MIYAURA Chisato
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Molecular aspects of vitamin D metabolism and action

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Study on Interaction between Osteoclast Progenitors and Osteoblastic Cells in Osteoclast Development.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Basic study on the risk factors of osteoporosis.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  The Role of Cytokines in Bone Resorption and Bone Formation

    • Principal Investigator
      ABE Etsuko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Rolo of Osteoblastic Cells in Osteoclast Development.Principal Investigator

    • Principal Investigator
      TAKAHASHI Naoyuki
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Establishment of Assay System for Studying Osteoblastic Function and Differentiation Using Newly Isolated Osteoblast-Like Cell Lines

    • Principal Investigator
      YOSHIKI Shusaku
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Establishment of the screening methods for bone-resorbing factors using in vitro osteoclast formation system.

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Role of the osteoclast and osteoblast during the bone resorption

    • Principal Investigator
      YOSHIKI Shusaku
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Two step model for the fusion of macrophages induced by 1alpha, 25-dihydroxyvitamin D_3

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Development of new assay systems for examining the relation between osteoblasts and osteoclasts, and identification of new factors controlling bone metabolism

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University, School of Dentistry
  •  Mechanisms of Fusion of Macrophages Induced by 1 ,25(OH)_2D_3

    • Principal Investigator
      SUDA Tatsuo
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] "破骨細胞はどのようにして骨組織にのみ形成されるのか"骨代謝実験医学臨時増刊号(田中栄編)2014

    • Author(s)
      高橋直之(分担執筆)
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "ビスホスホネートの作用機構"ファーマナビゲータービスホスホネート編2(松本俊夫、萩野浩編)2013

    • Author(s)
      小出雅則,高橋直之(分担執筆)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "カルシトニンと骨・ミネラル代謝"副甲状腺・骨代謝疾患診療マニュアル(竹内靖博編)2013

    • Author(s)
      小出雅則,高橋直之(分担執筆)
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] "ビタミンDのカルシウム代謝調節機構"ファーマナビゲーター活性型ビタミンD_3製剤編(太田博明、松本俊夫編)2012

    • Author(s)
      高橋直之(分担執筆)
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Book] Identification of osteoclasts in culture2011

    • Author(s)
      Udagawa N, Yamashita T, Kobayashi Y, Takahashi N, Nicole I zur Nieden
    • Publisher
      Springer Science
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Book] Identification of osteoclasts in culture. In Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases Series Methods in Molecular Biology2011

    • Author(s)
      Udagawa N, Yamashita T, Kobayashi Y, Takahashi N, Walker JM, zur Nieden NI
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Book] Principles of bone biology. Third edition, ed by Raisz LG, Martin TJ, Bilezikian JP2008

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      1700
    • Publisher
      Academic Press
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption. In Periodontal Medicine and Systems Biology2008

    • Author(s)
      Takahashi N
    • Publisher
      Blackwell Publishing,Oxford(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Principles of bone biology.Third edition, ed by Raisz LG, Martin TJ, Bilezikian JP2008

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      1700
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption.In Periodontal Medicine and Systems Biology2008

    • Author(s)
      Takahashi N
    • Publisher
      Academic Press,San Diego(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Methods in Molecular Medicine ed by Cope A. P.2007

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Total Pages
      430
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Book] Arthritis Research, Methods and Protocols Volume 1 "Generation of osteoclasts in vitro, and assay of osteoclast activity"2006

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Book] Generation of osteoclasts in vitro, and assay of osteoclast activity. In "Arthritis Research, Methods and Protocols Volume 1"(ed by Cop A.)2006

    • Author(s)
      Takahashi N.
    • Total Pages
      16
    • Publisher
      Humana Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Book] Arthritis Research, Methods and Protocols Volume 1 "Generation of osteoclasts in vitro, and assay of osteoclast activity"2006

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Book] Generation of osteoclasts in vitro, and assay of osteoclast activity. In "Arthritis Research, Methods and Protocols Volume 1" ed by Cop A2006

    • Author(s)
      Takahashi N.
    • Total Pages
      16
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-12137209
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-15659445
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592144
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Data Source
      KAKENHI-PROJECT-16390535
  • [Book] 硬組織研究ハンドブック2005

    • Author(s)
      高橋直之他
    • Total Pages
      264
    • Publisher
      松本歯科大学出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390535
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey (in press)
    • Data Source
      KAKENHI-PROJECT-16659578
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592180
  • [Book] Arthritis Research : Methods and Protocols2005

    • Author(s)
      Takahashi N et al.
    • Publisher
      Humana Press, Totowa, New Jersey(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390641
  • [Journal Article] Sclerostin expression in trabecular bone is downregulated by osteoclasts2020

    • Author(s)
      Masanori Koide, Teruhito Yamashita, Kohei Murakami, Shunsuke Uehara, Keigo Nakamura, Midori Nakamura, Mai Matsushita, Toshiaki Ara, Hisataka Yasuda, Josef M Penninger, Naoyuki Takahashi, Nobuyuki Udagawa, Yasuhiro Kobayashi
    • Journal Title

      Sci Rep .

      Volume: 10 Issue: 1 Pages: 13751-13751

    • DOI

      10.1038/s41598-020-70817-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10050, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-19K22729, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-17H01584, KAKENHI-PROJECT-18H02980, KAKENHI-PROJECT-18K09531, KAKENHI-PROJECT-19K18955
  • [Journal Article] Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment2019

    • Author(s)
      Ochiai Nagahiro、Nakachi Yutaka、Yokoo Tomotaka、Ichihara Takahiro、Eriksson Tore、Yonemoto Yuki、Kato Takehiko、Ogata Hitoshi、Fujimoto Natsuko、Kobayashi Yasuhiro、Udagawa Nobuyuki、Kaku Shinsuke、Ueki Tomokazu、Okazaki Yasushi、Takahashi Naoyuki、Suda Tatsuo
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s42003-019-0334-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08487, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776
  • [Journal Article] Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor-Marked Stromal Population from Adipogenic to Osteoblastic Lineage.2019

    • Author(s)
      Yang M, Arai A, Udagawa N, Zhao L, Nishida D, Murakami K, Hiraga T, Takao-Kawabata R, Matsuo K, Komori T, Kobayashi Y, Takahashi N, Isogai Y, Ishizuya T, Yamaguchi A, Mizoguchi T
    • Journal Title

      J Bone Miner Res

      Volume: 34 Issue: 10 Pages: 1952-1963

    • DOI

      10.1002/jbmr.3811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-19K18955, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-16KK0190, KAKENHI-PROJECT-19K22727
  • [Journal Article] Mechanisms involved in bone resorption regulated by vitamin D2018

    • Author(s)
      Nakamichi Yuko、Udagawa Nobuyuki、Suda Tatsuo、Takahashi Naoyuki
    • Journal Title

      The Journal of Steroid Biochemistry and Molecular Biology

      Volume: 177 Pages: 70-76

    • DOI

      10.1016/j.jsbmb.2017.11.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-15KK0356
  • [Journal Article] A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro.2017

    • Author(s)
      Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato H, Udagawa N and Nakamura Y
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 7 Pages: e0181126-e0181126

    • DOI

      10.1371/journal.pone.0181126

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401
  • [Journal Article] VDR in osteoblast-lineage cells primarily mediates vitamin D treatment-iInduced increase in bone mass by suppressing bone resorption.2017

    • Author(s)
      Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, Takahashi N
    • Journal Title

      J Bone Miner Res

      Volume: 32 Issue: 6 Pages: 1297-1308

    • DOI

      10.1002/jbmr.3096

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-16K11493, KAKENHI-PROJECT-16K11664, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-15KK0356, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11093
  • [Journal Article] Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis2017

    • Author(s)
      Ozaki Yuki、Koide Masanori、Furuya Yuriko、Ninomiya Tadashi、Yasuda Hisataka、Nakamura Midori、Kobayashi Yasuhiro、Takahashi Naoyuki、Yoshinari Nobuo、Udagawa Nobuyuki
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 9 Pages: e0184904-e0184904

    • DOI

      10.1371/journal.pone.0184904

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
  • [Journal Article] Bone Formation is coupled to resorption via suppression of sclerostin expression by osteoclasts.2017

    • Author(s)
      Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N and Udagawa N
    • Journal Title

      J Bone Mineral Res

      Volume: 32 Issue: 10 Pages: 2074-2086

    • DOI

      10.1002/jbmr.3175

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-26293392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-15K11402
  • [Journal Article] Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling.2017

    • Author(s)
      Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, Murakami K, Nishita M, Nakamura T, Kato S, Minami Y, Takahashi N and Kobayashi Y
    • Journal Title

      Sci Signal

      Volume: 10 Issue: 494

    • DOI

      10.1126/scisignal.aan0023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K07168, KAKENHI-PROJECT-17K08634, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-17K16686, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05152, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11377
  • [Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.2017

    • Author(s)
      Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N.
    • Journal Title

      Gen Comp Endocrinol.

      Volume: 246 Pages: 270-278

    • DOI

      10.1016/j.ygcen.2017.01.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508
  • [Journal Article] Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy2017

    • Author(s)
      Yang Mengyu、Arai Atsushi、Udagawa Nobuyuki、Hiraga Toru、Lijuan Zhao、Ito Susumu、Komori Toshihisa、Moriishi Takeshi、Matsuo Koichi、Shimoda Kouji、Zahalka Ali H.、Kobayashi Yasuhiro、Takahashi Naoyuki、Mizoguchi Toshihide
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 4928-4928

    • DOI

      10.1038/s41598-017-05401-1

    • NAID

      120006576162

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11798, KAKENHI-PROJECT-16K11818, KAKENHI-PROJECT-17K19776, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-17H04374, KAKENHI-PROJECT-15K11028, KAKENHI-PROJECT-15K11048, KAKENHI-PROJECT-15K11093, KAKENHI-PROJECT-16K15781, KAKENHI-PROJECT-26221310
  • [Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.2016

    • Author(s)
      Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y
    • Journal Title

      J Bone Miner Metab

      Volume: 34

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Journal Article] The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.2016

    • Author(s)
      Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y.
    • Journal Title

      J Bone Miner Metab

      Volume: 34 Issue: 4 Pages: 395-405

    • DOI

      10.1007/s00774-015-0683-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-16K11664
  • [Journal Article] Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.2016

    • Author(s)
      Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N
    • Journal Title

      Gen Comp Endocrinol

      Volume: 246 Pages: 270-278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Journal Article] Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.2015

    • Author(s)
      Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K.
    • Journal Title

      J Cell Sci

      Volume: 128 Pages: 4353-4365

    • DOI

      10.1242/jcs.176057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-15K18377, KAKENHI-PROJECT-15K21706
  • [Journal Article] The regulation of osteoclast differentiation by Wnt signals2015

    • Author(s)
      Kobayashi Y, Uehara S, Koide M, Takahashi N
    • Journal Title

      Bonekey Rep

      Volume: 4 Issue: 4 Pages: 713-713

    • DOI

      10.1093/jb/mvv124

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-16H05508, KAKENHI-PROJECT-15K11377, KAKENHI-PROJECT-16K11818
  • [Journal Article] Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a.2015

    • Author(s)
      Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 463 Issue: 4 Pages: 1278-1283

    • DOI

      10.1016/j.bbrc.2015.06.102

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11059, KAKENHI-PROJECT-15K11401, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26462826, KAKENHI-PROJECT-15K15688, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
  • [Journal Article] The regulation of osteoclast differentiation by Wnt signals.2015

    • Author(s)
      Kobayashi Y, Uehara S, Koide M, Takahashi N
    • Journal Title

      Bonekey Rep

      Volume: 4 Pages: 713-713

    • DOI

      10.1038/bonekey.2015.82

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814, KAKENHI-PROJECT-25293423
  • [Journal Article] Osteoclast Cell Lineage2014

    • Author(s)
      Takahashi N, Mizoguchi T, Nakamichi Y, Kobayashi Y, Nakamura M, Willy Hofstetter W, Udagawa N
    • Journal Title

      Characteristics and behavior of osteoclast precursors in vivo Encyclopedia of Human Body 3^<rd> Edition

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] Stability of mRNA influences steoporotic bone mass via CNOT32014

    • Author(s)
      Watanabe, C. Morita, M. Yamamoto T. (13名)
    • Journal Title

      Natl Acad Sci U S A

      Volume: Vol.111 Issue: 7 Pages: 2692-2697

    • DOI

      10.1073/pnas.1316932111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-23390471, KAKENHI-PROJECT-24659833, KAKENHI-PUBLICLY-25121734, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462287, KAKENHI-PROJECT-25463168, KAKENHI-PROJECT-25670639, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-26670814
  • [Journal Article] Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways.2014

    • Author(s)
      Yamashita T, Uehara S, Udagawa N, Li F, Kadota S, Esumi H, Kobayashi Y, Takahashi N
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: 85878-85878

    • DOI

      10.1371/journal.pone.0085878

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
  • [Journal Article] VitaminD endocrine system and osteoclasts2014

    • Author(s)
      Takahashi N, Udagawa N, Suda T
    • Journal Title

      BoneKEy Reports

      Volume: 3 Pages: 495-495

    • DOI

      10.1038/bonekey.2013.229

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-26670814
  • [Journal Article] oles of cathelicidins in inflammation and bone loss.2014

    • Author(s)
      Nakamichi Y, Horibe K, Udagawa N, Takahashi N
    • Journal Title

      Odontology

      Volume: 101 Issue: 2 Pages: 137-146

    • DOI

      10.1007/s10266-014-0167-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-26670814
  • [Journal Article] Osteoclasts polarize on dental implant materials as if they were on bone2014

    • Author(s)
      Nakayama T, Thirukond GJ, Nagasaw S, Kawahara I, Udagawa N, Yagami K, Kawatani M, Osada H, Doi Y, Yoshinaria N, Takahashi N
    • Journal Title

      J Oral Biosci

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] Noncanonical Wnt5a enhances Wnt/&#61538;-catenin signaling during osteogenesis.2014

    • Author(s)
      Okamoto, M., Udagawa, N., Yamashita, T., Nakamichi, Y., Uehara, S., Kato, H., Saito, N., Minami, Y., Takahashi, N., Kobayashi, Y.
    • Journal Title

      Sci. report

      Volume: 4 Issue: 1 Pages: 4493-4493

    • DOI

      10.1038/srep04493

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24240076, KAKENHI-PROJECT-24241045, KAKENHI-PROJECT-24390080, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25462385, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25670793, KAKENHI-PROJECT-26462825, KAKENHI-PROJECT-26670814
  • [Journal Article] IL-34 and CSF-1 similarities and differences2013

    • Author(s)
      Nakamichi Y, Udagawa N, Takahashi N
    • Journal Title

      J Bone Miner Metab

      Volume: 31 Issue: 5 Pages: 486-495

    • DOI

      10.1007/s00774-013-0476-3

    • NAID

      10031201682

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25462905, KAKENHI-PROJECT-25670793
  • [Journal Article] Roles of Wnt signals in bone resorption during physiological and pathological states.2013

    • Author(s)
      Maeda K et al.
    • Journal Title

      J Mol Med (Berl)

      Volume: 91 Issue: 1 Pages: 15-23

    • DOI

      10.1007/s00109-012-0974-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310
  • [Journal Article] Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis2013

    • Author(s)
      Horibe K, Kobayashi Y, Takahashi N, Udagawa N(他4名)
    • Journal Title

      Immunology

      Volume: 140 Issue: 3 Pages: 344-351

    • DOI

      10.1111/imm.12146

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25253097, KAKENHI-PROJECT-25462904, KAKENHI-PROJECT-25462905
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo2013

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 136(pii : S0960-0760(12)00243-9) Pages: 171-174

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss: Comparison with RANKL-overexpressing transgenic male mice.2013

    • Author(s)
      Koide M et al.
    • Journal Title

      Endocrinology

      Volume: 190 Issue: 2 Pages: 773-782

    • DOI

      10.1210/en.2012-1928

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23593027, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24592786, KAKENHI-PROJECT-24592849, KAKENHI-PROJECT-24593112, KAKENHI-PROJECT-24593132, KAKENHI-PROJECT-24659833, KAKENHI-PROJECT-25221310, KAKENHI-PROJECT-25670793
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo.2013

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 136 Pages: 171-174

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Journal Article] Regulation of Osteoclast Function. Mod Rheumatol, 22:167-177, 2012.Suda T, Takahashi F, Takahashi N Bone Effects of vitamin D-Discrepancies between in vivo and in vitro studies -2012

    • Author(s)
      Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T
    • Journal Title

      Arch Biochem Biophys

      Volume: 523 Issue: 2 Pages: 22-29

    • DOI

      10.1007/s10165-011-0530-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-24659833
  • [Journal Article] Wnt5a-Ror2 signaling between osteoblasts and osteoclast precursors enhances osteoclastogenesis2012

    • Author(s)
      Maeda, K., Kobayashi, Y., Udagawa, N., Uehara, S., Ishihara, A., Mizoguchi, T., Kikuchi, Y., Takada, I., Kato, S., Kani, S., Nishita, M., Marumo, K., Martin, T.J., Minami, Y., Takahashi, N.
    • Journal Title

      Nat.Med.

      Volume: (印刷中) Issue: 3 Pages: 405-12

    • DOI

      10.1038/nm.2653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390080, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PUBLICLY-22021039, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22790291, KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23650595, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-23791668, KAKENHI-PROJECT-23792134, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] Bone Effects of vitamin D -Discrepancies between in vivo and in vitro studies -.2012

    • Author(s)
      Suda T
    • Journal Title

      Arch Biochem Biophys

      Volume: 523 Issue: 1 Pages: 22-29

    • DOI

      10.1016/j.abb.2011.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-24659833
  • [Journal Article] c-Fms signaling mediates neurofibromatosis type-1 osteoclast gain-in-functions2012

    • Author(s)
      He Y, Rhodes SD, Chen S, Wu X, Yuan J, Yang X, Jiang L, Li X, Takahashi N, Xu M, Mohammad KS, Guise TA, Yang FC
    • Journal Title

      PLOS ONE

      Volume: 7 Issue: 11 Pages: 46900-46900

    • DOI

      10.1371/journal.pone.0046900

    • Data Source
      KAKENHI-PROJECT-24659833
  • [Journal Article] an active vitamin D analog, on bone resorption in vivo2012

    • Author(s)
      Takahashi N: Mechanism of inhibitory action of Eldecalcitol
    • Journal Title

      J Steroid Biochem Mol Biol

      Pages: 960-760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Daily administration of Eldecalcitol (ED-71), an active vitamin Danalog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone2012

    • Author(s)
      Harada S, et al
    • Journal Title

      J Bone Miner Res

      Volume: 27 Issue: 2 Pages: 461-473

    • DOI

      10.1002/jbmr.555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135
  • [Journal Article] New roles of osteoblasts involved in osteoclast differentiation.2012

    • Author(s)
      Yamashita T, Takahashi N, Udagawa N
    • Journal Title

      World J Osteoarthritis

      Volume: 3 Issue: 11 Pages: 175-181

    • DOI

      10.5312/wjo.v3.i11.175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-24592821, KAKENHI-PROJECT-24659833
  • [Journal Article] Mechanism of inhibitory action of Eldecalcitol, an active vitamin D analog, on bone resorption in vivo.2012

    • Author(s)
      Takahashi N
    • Journal Title

      J Steroid Biochem Mol Biol

      Volume: 12 Pages: 243-249

    • DOI

      10.1016/j.jsbmb.2012.11.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Tetracyclines convert the osteoclastic-differentiation pathway of orogenitor cells to produce dendritic cell-like cells2012

    • Author(s)
      Kinugawa S, et al
    • Journal Title

      J Immunol

      Volume: 188 Issue: 4 Pages: 1772-1781

    • DOI

      10.4049/jimmunol.1101174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22792102, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792492, KAKENHI-PROJECT-24592786
  • [Journal Article] Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts2012

    • Author(s)
      Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N
    • Journal Title

      Advanced Materials

      Volume: 24 Issue: 16 Pages: 2176-2185

    • DOI

      10.1002/adma.201103832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002007, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-24659833
  • [Journal Article] Polarized osteoclasts put marks of tartate-resistant acid phosphatase on dentine slices-a simple method for identifying polarized osteoclasts2012

    • Author(s)
      Nakayama T, et al
    • Journal Title

      Bone

      Volume: 49 Issue: 6 Pages: 1331-1339

    • DOI

      10.1016/j.bone.2011.09.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792134
  • [Journal Article] Regulation of Osteoclast Function2012

    • Author(s)
      Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T
    • Journal Title

      Mod Rheumatol

      Volume: 22(2) Pages: 167-177

    • NAID

      10030614771

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21953286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012

    • Author(s)
      Arai A, et al
    • Journal Title

      J Cell Sci

      Volume: (印刷中) Pages: 2910-2917

    • DOI

      10.1242/jcs.099986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22791804, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.2012

    • Author(s)
      Nakamichi Y et al.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 109 Issue: 25 Pages: 10006-10011

    • DOI

      10.1073/pnas.1207361109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-23659972, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-24390417, KAKENHI-PROJECT-24659833
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment2012

    • Author(s)
      Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
    • Journal Title

      J. Cell Sci

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front. Biosci

      Volume: 16 Pages: 21-30

    • URL

      http://dx.doi.org/10.2741/3673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-a simple method for identifying polarized osteoclasts2011

    • Author(s)
      Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Bone

      Volume: 49 Pages: 1331-1339

    • URL

      http://dx.doi.org/10.1016/j.bone.2011.09.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Increased bone mass in mice after a single injection of an anti-RANKL neutralizing antibody : evidence for a bone anabolic effect of PTH in mice with few osteoclasts2011

    • Author(s)
      Furuya Y, et al
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 42 Pages: 37023-37031

    • DOI

      10.1074/jbc.m111.246280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23659883
  • [Journal Article] Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices-A simple method for identifying polarized osteoclasts-2011

    • Author(s)
      Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Bone

      Volume: 49(6) Pages: 1331-1339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Lineage-Committed Osteoclast Precursors Circulate in Blood and Settle Down Into Bone2011

    • Author(s)
      Muto, A, Mizoguchi, T, Udagawa, N., Ito, S, Kawahara, I, Abiko, Y, Arai, A., Harada, S., Kobayashi, Y., Nakamichi, Y, Penninger, JM, Noguchi, T, Takahashi, N.
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 26 Issue: 12 Pages: 2978-2990

    • DOI

      10.1002/jbmr.490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390498, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21390550, KAKENHI-PROJECT-21390551, KAKENHI-PROJECT-21592615, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23593074, KAKENHI-PROJECT-23792135, KAKENHI-PROJECT-23792455, KAKENHI-PROJECT-23792492
  • [Journal Article] Hyergravity suppresses bone resorption in ovariectomized rat2011

    • Author(s)
      Ikawa T, et al
    • Journal Title

      Adv Space Res

      Volume: 47 Issue: 7 Pages: 1214-1224

    • DOI

      10.1016/j.asr.2010.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-22659339, KAKENHI-PROJECT-23593054, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-23792135
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.2011

    • Author(s)
      Takahashi N, et.al.
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Identification of osteoclasts in culture2011

    • Author(s)
      Udagawa N, et al
    • Journal Title

      Methods Mol Biol

      Volume: 690 Pages: 273-284

    • DOI

      10.1007/978-1-60761-962-8_18

    • ISBN
      9781607619611, 9781607619628
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378, KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21196156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.2011

    • Author(s)
      Takahashi N, Maeda K, Ishihara A, Uehara S, Kobayashi Y
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice2010

    • Author(s)
      Lee JW, Kobayashi Y, Nakamichi Y, Udagawa N, Takahashi N, Im NK, Seo HJ, Jeon WB, Yonezawa T, Cha BY, Woo JT.
    • Journal Title

      Biochem. Pharmacol

      Volume: 80 Pages: 352-361

    • URL

      http://dx.doi.org/10.1016/j.bcp.2010.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis.2010

    • Author(s)
      Aoki S, Nakamichi Y, Ninomiya T, Takahashi N, Udagawa N
    • Journal Title

      J Bone Miner Res. 25

      Pages: 1907-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, Muto A, Arai A, Mizoguchi T
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • DOI

      10.1007/978-1-4419-1050-9_3

    • ISBN
      9781441910493, 9781441910509
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2010

    • Author(s)
      Takahashi N, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 658 Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Osteoclastic bone resorption induced by innate immune responses.2010

    • Author(s)
      Koide M, Kinugawa S, Takahashi N, Udagawa N.
    • Journal Title

      Periodontol 2000. 54

      Pages: 235-246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2010

    • Author(s)
      Takahashi N, Mizoguchi T
    • Journal Title

      Adv Exp Med Biol. 658

      Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo2010

    • Author(s)
      Naoyuki Takahashi
    • Journal Title

      Adv Exp Med Biol. 658

      Pages: 21-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Osteoclastic bone resorption induced by innate immune responses.2010

    • Author(s)
      Koide M, Kinugawa S, Takahashi N, UdagawaN.
    • Journal Title

      Perriodontol

      Volume: 54 Issue: 1 Pages: 235-46

    • DOI

      10.1111/j.1600-0757.2010.00355.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351, KAKENHI-PROJECT-22792102
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009

    • Author(s)
      Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N
    • Journal Title

      J Cell Biol 184

      Pages: 541-554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2009

    • Author(s)
      Takahashi M, Mizoguchi T, Uehara S, Nakamichi Y, Yang S, Naramoto H, Yamashita T, Kobayashi Y, Yamaoka M, Furusawa K, Udagawa N, Uematsu T, Takahashi N
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling2009

    • Author(s)
      Koide M, Kinugawa S, Ninomiya T, Mizoguchi T, Yamashita T, Maeda K, Yasuda H, Kobayashi Y, Nakamura H, Takahashi N, Udagawa N
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 24(8) Issue: 8 Pages: 1469-1480

    • DOI

      10.1359/jbmr.090302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.2009

    • Author(s)
      Narita N, Nakamura H, Mizoguchi T, Ozawa H, Udagawa N, Takahashi N
    • Journal Title

      Nano Lett. 9

      Pages: 1406-1413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2009

    • Author(s)
      Takahashi M, et al.
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function different manners.2009

    • Author(s)
      Takahashi M, Mizoguchi T, Nakamichi Y, Yamashita T, Udagawa N, Takahashi N
    • Journal Title

      J. Bone Miner. Metab. 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners2009

    • Author(s)
      Takahashi M, et al.
    • Journal Title

      J Bone Miner Metab 27

      Pages: 24-35

    • NAID

      10025336084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592378
  • [Journal Article] Formation of bone -like mineralized matrix by periodontal ligament cells in vivo : a morphological study in rats.2009

    • Author(s)
      Hiraga T, Ninomiya T, Hosoya A, Takahashi M, Nakamura H
    • Journal Title

      J Bone Miner Metab. 27

      Pages: 149-157

    • NAID

      10025336621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009

    • Author(s)
      Mizoguchi T, Muto A, Udagawa N, Arai A, Yamashita T, Hosoya A, Ninomiya T, Nakamura H, Yamamoto Y, Kinugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, Nagasawa S, Oda K, Tanaka H, Tagaya M, Penninger JM, Ito M, Takahashi N.
    • Journal Title

      J Cell Biol

      Volume: 184(4) Issue: 4 Pages: 541-54

    • DOI

      10.1083/jcb.200806139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-21592378
  • [Journal Article] Action of RANKL and OPG for osteoclastogenesis2009

    • Author(s)
      Kobayashi Y, Udagawa N, Takahashi N
    • Journal Title

      Crit. Rev. Eukaryot. Gene Expr

      Volume: 19 Pages: 61-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Journal Article] Diphenylhydantoin inhibits osteoclast differentiation and function through suppression of NFATc1 signaling.2009

    • Author(s)
      Koide M, Nynomiya T, Mizoguchi T, Yamashita T, Nakamura H, Takahashi N, Udagawa N
    • Journal Title

      J Bone Miner Res. 24

      Pages: 1469-1480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] The relationship between calcium accumulation in osteoclast mitochondrial granules and bone resorption.2009

    • Author(s)
      Kawahara I, Koide M, Tadokoro O, Udagawa N, Nakamura H, Takahashi N, Ozawa H
    • Journal Title

      Bone. 45

      Pages: 980-986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Identification of cell cycle-arrested quiescent osteoclast precursors in vivo.2009

    • Author(s)
      Mizoguchi T, Udagawa N, Yamashita T, Hosoya A, Ninomiya T, Nakamichi Y, Takahashi N
    • Journal Title

      J Cell Biol. 184

      Pages: 541-554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200019
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast for mation and function in different manners2008

    • Author(s)
      Takahashi M, et. al.
    • Journal Title

      J Bone Miner Metab 27(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Journal Article] MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts.2008

    • Author(s)
      Yamashita T, Kobayashi Y, Mizoguchi T, Yamaki M, Miura T, Tanaka S, Udagawa N, Takahashi N
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 252-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Current paradigms of osteoblast-osteoclast interactions and bacterial pathogen-induced bone resorption.2008

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Periodontal Medicine and Systems Biology, Blackwell Publishing, Oxford (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.2008

    • Author(s)
      Takahashi M, Takahashi M, Mizoguchi T, Uehara S, Nakamichi Y, Yang S, Naramoto H, Yamashita T, Kobayashi Y, Furusawa K, Yamaoka M, Udagawa N, Uematsu T, Takahashi N
    • Journal Title

      J Bone Miner Metab (in press)

    • NAID

      10025336084

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592119
  • [Journal Article] Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners2008

    • Author(s)
      Takahashi M, et. al.
    • Journal Title

      J Bone Miner Metab (In press)

    • NAID

      10025336084

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Osteoclast generation2008

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Principles of bone biology Third edition, Academic Press, San Diego (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Odontology 95

      Pages: 1-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Naoyuki Takahashi
    • Journal Title

      Methods. Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Journal Article] 破骨細胞の形成部位を決める破骨細胞ニッチ2007

    • Author(s)
      高橋直之
    • Journal Title

      医学の歩み 221

      Pages: 285-301

    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro,and assay of osteoclast activity2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity2007

    • Author(s)
      Takahashi N
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization2007

    • Author(s)
      Takahashi N
    • Journal Title

      Odontology 95

      Pages: 252-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Regulation of osteoclast polarization.2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Odontology 95

      Pages: 1-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Generation of osteoclasts in vitro,and assay of osteoclast activity2007

    • Author(s)
      Naoyuki Takahashi, et. al.
    • Journal Title

      Methods.Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390557
  • [Journal Article] Generation of osteoclasts in vitro, and assay of osteoclast activity.2007

    • Author(s)
      Takahashi N, et. al.
    • Journal Title

      Methods Mol Med 135

      Pages: 285-301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Journal Article] Synergistic effects of FGF-2 with insulin or IGF-1 on the proliferation of human auricular chondrocytes.2005

    • Author(s)
      Takahashi T. et al.
    • Journal Title

      Cell Transplant 14・9

      Pages: 683-693

    • Data Source
      KAKENHI-PROJECT-16659506
  • [Journal Article] Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in CSF-1^<op/op> mice

    • Author(s)
      Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato S, DeLuca HF, Suda T, Udagawa N, Takahashi N
    • Journal Title

      Proc Natl Acad Sci UAS

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling.

    • Author(s)
      Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
    • Journal Title

      Inflammation and Regeneration

      Volume: (In press)

    • NAID

      130004943807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Journal Article] Regulation of osteoclast polarization.

    • Author(s)
      Takahashi N. et al.
    • Journal Title

      Odontology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591924
  • [Journal Article] c-Fos plays an essential role in the up-regulation of RANK expression in osteoclast precursors within the bone microenvironment

    • Author(s)
      Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N
    • Journal Title

      J Cell Science

      Volume: (In press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/22454522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulatory mechanism of osteoclastogenesis by Wnt signaling

    • Author(s)
      Kobayashi Y, Maeda K, Uehara S, Yamashita T, Takahashi N
    • Journal Title

      Inflammation and Regeneration

      Volume: (In press)

    • NAID

      130004943807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Journal Article] Regulation of osteoclast polarization

    • Author(s)
      Takahashi N. et al.
    • Journal Title

      Odentology (in press)

    • Data Source
      KAKENHI-PROJECT-17591924
  • [Journal Article] Bone Effects of vitamin D-Discrepancies between in vivo and in vitro studies-

    • Author(s)
      Suda T, Takahashi F, Takahashi N
    • Journal Title

      Arch Biochem Biophys

      Volume: (In press)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/22107950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Wnt/β-cateninシグナルの制御系をモニターするSost-Greenレポーターマウスの作出2019

    • Author(s)
      山下照仁,小出雅則,堀部寛治,上原俊介,宇田川信之,高橋直之,中村浩彰,小林泰浩
    • Organizer
      第88回松本歯科大学学会総会
    • Data Source
      KAKENHI-PROJECT-18K09531
  • [Presentation] 破骨細胞生物学の歴史:RANKL発見までを振り返る。2019

    • Author(s)
      高橋直之
    • Organizer
      松本歯科大学総合歯科医学研究所開設30年記念講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Osteoclasts promote trabecular bone formation through the suppression of sclerostin expression2019

    • Author(s)
      Masanori Koide, Yasuhiro Kobayashi, Teruhito Yamashita, Kohei Murakami, Shunsuke Uehara, Hisataka Yasuda, Naoyuki Takahashi, Nobuyuki Udagawa
    • Organizer
      The American Society for Bone and Mineral Research (ASBMR) 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09531
  • [Presentation] なぜ共存培養だったのか.2018

    • Author(s)
      高橋直之
    • Organizer
      2018 Dentistry Quo Vadis?
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] 破骨細胞研究の歴史を振り返る2018

    • Author(s)
      高橋直之
    • Organizer
      第36回日本骨代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] How does vitamin D regulate osteoclastic bone resorption?2018

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      17th Annual Meeting of Korean Association of Oral Science
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Progress of osteoclast biology2017

    • Author(s)
      高橋直之
    • Organizer
      第2回日本骨免疫学会ウィンターセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] 須田先生と骨代謝研究2017

    • Author(s)
      高橋直之
    • Organizer
      第35回日本骨代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] デノスマブが骨代謝研究に与えた影響2017

    • Author(s)
      高橋直之
    • Organizer
      2017年Dentistry, Quo Vadis?
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] Wnt5a-Ror2シグナルにより活性化されるRor-Pkn3経路はc-Srcを介して骨吸収を調節する。2016

    • Author(s)
      上原俊介、山下照仁、中村 貴、加藤茂明、宇田川信之、高橋直之、小林泰浩
    • Organizer
      第34回日本骨代謝学会
    • Place of Presentation
      大阪国際会議場、大阪市北区中之島
    • Year and Date
      2016-07-21
    • Data Source
      KAKENHI-PROJECT-16H05144
  • [Presentation] いまデンティストリーに骨代謝がなぜ必要か2015

    • Author(s)
      高橋直之
    • Organizer
      Dentistry, Quo Vadis?
    • Place of Presentation
      星陵会館 (東京都千代田区)
    • Year and Date
      2015-12-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の研究からわかってきたこと2015

    • Author(s)
      高橋直之
    • Organizer
      歯科基礎平成27年度社員総会
    • Place of Presentation
      日本歯科大学富士見ホール(東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 破骨細胞研究から学んだこと2015

    • Author(s)
      高橋直之
    • Organizer
      平成27年度大阪歯科学会大会
    • Place of Presentation
      大阪歯科大学創立100周年記念館 (大阪市中央区)
    • Year and Date
      2015-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の研究からわかってきたこと2015

    • Author(s)
      高橋直之
    • Organizer
      歯科基礎平成27年度社員総会 生化学分野 分科会講演会
    • Place of Presentation
      日本歯科大学富士見ホール (東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] アルクチゲニンの破骨細胞分化抑制メカニズム2014

    • Author(s)
      山下照仁,小林泰浩,上原俊介,宇田川信之,李峰,門田重利,江角浩安,高橋直之
    • Organizer
      第56回歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナル2014

    • Author(s)
      高橋直之
    • Organizer
      第一回日本骨免疫会議
    • Place of Presentation
      万国津梁館 名護市喜瀬
    • Year and Date
      2014-07-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 抗炎症作用を持つアルクチゲニンの破骨細胞抑制メカニズム2014

    • Author(s)
      山下照仁,小林泰浩,上原俊介,宇田川信之,李峰,門田重利,江角浩安,高橋直之
    • Organizer
      第1回日本骨免疫会議
    • Place of Presentation
      万国津梁館(名護市)
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞はどのような機序で骨組織に誘導される2014

    • Author(s)
      高橋直之
    • Organizer
      第45回京都骨・カルシウム代謝研究会
    • Place of Presentation
      ホテルグランヴィア京都、京都市 下京区
    • Year and Date
      2014-11-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      長良川国際会議場 岐阜市長良福光
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      長良川国際会議場  岐阜市長良福光
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] Arctigenin Inhibits Osteoclastogenesis by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways2014

    • Author(s)
      Yamashita T,Uehara S,Udagawa N,Li F,Kadota S,Esumi H,Kobayashi Y,Takahashi N
    • Organizer
      ASBMR 2014 Annual Meeting
    • Place of Presentation
      George R. Brown Convention Center (Houston, USA)
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 歯周病において破骨細胞はどのように誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第57回春季日本歯周病学会
    • Place of Presentation
      岐阜
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞はどのような機序で骨組織に誘導されるか2014

    • Author(s)
      高橋直之
    • Organizer
      第45回京都骨・カルシウム代謝研究会
    • Place of Presentation
      ホテルグランヴィア京都、京都市下京区
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670814
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナ2014

    • Author(s)
      高橋直之
    • Organizer
      第一回日本骨免疫会議
    • Place of Presentation
      万国津梁館  名護市喜瀬
    • Year and Date
      2014-07-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞前駆細胞を制御する骨芽細胞の新しい役割2013

    • Author(s)
      高橋直之
    • Organizer
      第15回骨とリウマチ研究会
    • Place of Presentation
      東京
    • Year and Date
      2013-01-31
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of anti-bone resorptive action of eldecalcitol2013

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Advisory meeting of active vitamin D
    • Place of Presentation
      Kobe
    • Year and Date
      2013-05-28
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANKシグナル2013

    • Author(s)
      高橋直之
    • Organizer
      城北骨代謝フォーラム東京
    • Place of Presentation
      東京
    • Year and Date
      2013-10-29
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能を調節するRANKL-RANK シグナル2013

    • Author(s)
      高橋直之
    • Organizer
      城北骨代謝フォーラム
    • Place of Presentation
      ホテルグランドシティー 豊島区東池袋
    • Year and Date
      2013-10-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      星陵会館 千代田区永田町
    • Year and Date
      2013-12-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221310
  • [Presentation] 破骨細胞の分化と機能の調節機構2013

    • Author(s)
      高橋直之
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Wnt5a enhances Wnt/beta-catenin signaling through the up-regulation of Lrp5/6 during osteogenesis2013

    • Author(s)
      Okamoto M, UdagawaN, Yamashita T, Uehara S, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y
    • Organizer
      2013 米国骨代謝学会
    • Place of Presentation
      Baltimore Convention Center, USA
    • Data Source
      KAKENHI-PROJECT-25293423
  • [Presentation] チタンインプラント埋入における生体側のイベントII2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis?
    • Place of Presentation
      東京
    • Year and Date
      2013-12-08
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] インプラントはOsseointegrationをどのように獲得するか2013

    • Author(s)
      高橋直之
    • Organizer
      松本歯科大学インプラントカンファレンス
    • Place of Presentation
      塩尻
    • Year and Date
      2013-06-10
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts2013

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6^<th> International symposium on the biology of tartrate resistant acid phosphatase
    • Place of Presentation
      Kobe
    • Year and Date
      2013-05-27
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係2013

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      東京
    • Year and Date
      2013-12-07
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨吸収を調節するWntシグナル2013

    • Author(s)
      高橋直之
    • Organizer
      第4回彩の国骨フォーラム
    • Place of Presentation
      埼玉
    • Year and Date
      2013-02-08
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of inhibitory action of eldecalcitol, an active vitamin D analog, on bone resorption in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      5^<th> Workshop on Vitamin D
    • Place of Presentation
      Huston
    • Year and Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] チタンインプラント埋入における生体側のイベントII2012

    • Author(s)
      高橋直之
    • Place of Presentation
      東京
    • Year and Date
      2012-12-08
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収の調節機構2012

    • Author(s)
      高橋直之
    • Organizer
      鹿児島大学歯学部セミナー
    • Place of Presentation
      鹿児島
    • Year and Date
      2012-01-16
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Mechanism of inhibitory action of eldecalcitol an active vitamin D analog, on bone resorption in vivo.2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture, 5th Workshop on Vitamin D
    • Place of Presentation
      Huston
    • Year and Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Osteoclast precursors in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      東京医科歯科大学GCOE
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Osteoclast precursors in vivo2012

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      東京医科歯科大学 GCOE
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化を調節する骨芽 細胞の新しい役割2012

    • Author(s)
      高橋直之
    • Organizer
      創価大学セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞はどのように骨を認識し 極性化するか日本歯科理工学会・2012

    • Author(s)
      高橋直之
    • Organizer
      中部支部夏季セミナー
    • Place of Presentation
      妙高高原
    • Year and Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化と機能の調節機構2012

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院セミナー
    • Place of Presentation
      福岡
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞の分化を調節する骨芽細胞の新しい役割2012

    • Author(s)
      高橋直之
    • Organizer
      創価大学セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞はどのように骨を認識し極性化するか2012

    • Author(s)
      高橋直之
    • Organizer
      日本歯科理工学会・中部支部夏季セミナー
    • Place of Presentation
      妙高高原
    • Year and Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Place of Presentation
      長崎県医師会館(長崎)(招待講演)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 分子メカニズムを知る意味とは2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-11
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] チタンインプラント埋入における生 体側のイベント2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Place of Presentation
      Gold Coast Convention center Gold Coast, Autraria(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Place of Presentation
      長崎県医師会館(長崎)(招待講演)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 分子メカニズムを知る意味とは(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-11
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節する骨芽細胞の新 しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      第26回長崎骨粗鬆症研究会
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] チタンインプラント埋入における生体側のイベント(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture 2^<nd> Asia-Pacific Osteoporosis and Bone Meeting
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors.2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Invited lecture 2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞を制御する骨芽細胞の新しい役割(招待講演)2011

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院講義
    • Place of Presentation
      福岡
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 破骨細胞を制御する骨芽細胞の新しい役割2011

    • Author(s)
      高橋直之
    • Organizer
      九州大学大学院講義
    • Place of Presentation
      福岡
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収の調節機構2011

    • Author(s)
      高橋直之
    • Organizer
      鹿児島大学歯学部セミナー
    • Year and Date
      2011-01-16
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] Quiescent Osteoclast Precursors2011

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      2nd Asia-Pacific Osteoporosis and Bone Meeting
    • Place of Presentation
      Gold Coast Convention Center Gold Coast, Autraria(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Characteristics of osteoclast precursors in vivo.2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      7th Meeting of Bone Biology Forum
    • Place of Presentation
      Susono,Japan
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節するRANKL-RANK系2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会,ランチョンセミナー
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 破骨細胞形成を調節する骨芽細 胞の新しい役割2010

    • Author(s)
      高橋直之
    • Organizer
      第10回徳島 Bone Forum
    • Place of Presentation
      徳島
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Sheraton Grande Walkerhill, 韓国
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨吸収を調節するRANKL-RANK 系2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会, ランチョンセミナー
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 漢方牛蒡子由来のアルクチゲニンは破骨細胞の機能と分化を抑制する2010

    • Author(s)
      山下照仁、上原俊介、小林泰浩、宇田川信之、高橋直之
    • Organizer
      第28回日本骨代謝学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis. Invited lecture2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Satellite Symposium) 22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Noncanonical Wnt signaling and osteoclastogenesis2010

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      22nd Meeting of Korean Society of Bone Metabolism
    • Place of Presentation
      Sheraton Grande Walkerhill, 韓国
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-22659339
  • [Presentation] 骨吸収を調節するRANKL-RANK 系. ランチョンセミナー2010

    • Author(s)
      高橋直之
    • Organizer
      第28回日本骨代謝会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Wnt5aはRANKの発現を亢進し、破骨細胞分化を促進する2010

    • Author(s)
      小林泰浩, 前田和洋、上原俊介、高田伊知郎、加藤茂明、丸毛啓史、宇田川信之、高橋直之
    • Organizer
      第28回日本骨代謝学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] 破骨細胞前駆細胞の起源と動態.2010

    • Author(s)
      高橋直之
    • Organizer
      第31回に本炎症・再生学会ミニシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] Wntシグナルによる破骨細胞分化調節機構の解析2010

    • Author(s)
      小林泰浩、溝口利英、上原俊介、高橋直之、宇田川信之
    • Organizer
      第71回松本歯科大学学会例会
    • Place of Presentation
      塩尻
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-21390551
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis.2007

    • Author(s)
      Takahashi N
    • Organizer
      ASBMR Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2007-12-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] A new role of osteoblasts in osteoclastogenesis.2007

    • Author(s)
      Takahashi N
    • Organizer
      The 22nd annual Research Meeting of the Japanese Orthopaedic Association
    • Place of Presentation
      Hamamatsu
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] In vivoにおいて細胞周期の停止した破骨細胞前駆細胞(pOCP)は5-FU非感受性である2007

    • Author(s)
      溝口利英、武藤昭紀、細矢明宏、中道裕子、山下照仁、小林泰浩、宇田川信之、伊藤充雄、高橋直之
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪市大阪国際会議場
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2007

    • Author(s)
      高橋 直之
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis2007

    • Author(s)
      Takahashi N
    • Organizer
      ASBMR Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis.
    • Place of Presentation
      Washington DC,USA
    • Year and Date
      2007-12-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] The RANK ligand-OPG system and a new role of osteoblasts in osteoclastogenesis2007

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      米国骨代謝学会(ASBMR)Meeting of Targeting Bone Remodeling for the Treatment of Osteoporosis
    • Place of Presentation
      Washington DC
    • Year and Date
      2007-12-06
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] 破骨細胞のMAPキナーゼp38経路を制御する因子Alixの同定2007

    • Author(s)
      山下照仁、溝口利英、小林泰浩、二宮 禎、宇田川信之、高橋直之
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪市大阪国際会議場
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19592163
  • [Presentation] 骨芽細胞による骨吸収調節機構-新しい考え方-2007

    • Author(s)
      高橋直之
    • Organizer
      第2回信州骨粗鬆症セミナー
    • Place of Presentation
      松本市
    • Year and Date
      2007-09-22
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] 骨吸収を調節する骨芽細胞の新しい役割2007

    • Author(s)
      高橋直之
    • Organizer
      第22回日本整形外科学会基礎学術集会教育講演
    • Place of Presentation
      浜松市
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18390495
  • [Presentation] チタンインプラント埋入における生体側のイベント

    • Author(s)
      高橋直之
    • Organizer
      Dentistry Quo Vadis?
    • Place of Presentation
      星陵会館 (東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of inhibitory action of eldecalcitol, an active vitamin D analog, on bone resorption in vivo.

    • Author(s)
      Takahashi naoyuki
    • Organizer
      5th Workshop on Vitamin D
    • Place of Presentation
      Huston、米国
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390351
  • [Presentation] 骨芽細胞と破骨細胞、そして力の関係

    • Author(s)
      高橋直之
    • Organizer
      Dentistry、Quo Vadis?
    • Place of Presentation
      星陵会館(東京都、千代田区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] 破骨細胞の分化と機能の調節機構

    • Author(s)
      高橋直之
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島グリーンアリーナ[広島県、広島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Mechanism of anti-bone resorptive action of eldecalcitol.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      Advisory meeting of active vitamin D
    • Place of Presentation
      神戸ポートピアホテル(兵庫県、神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts. 6th International symposium on the biology of tartrate resistant acid phosphatase.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6th International symposium on the biology of tartrate resistant acid phosphatase.
    • Place of Presentation
      神戸ポートピアホテル(兵庫県、神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • [Presentation] Arctigenin Inhibits Transcriptional Activity of NFATc1 by Its Nuclear Translocation- Independent Mechanism

    • Author(s)
      Yamashita T,Uehara S,Udagawa N,Kobayashi Y,Takahashi N
    • Organizer
      国際骨代謝学会および日本骨代謝学会
    • Place of Presentation
      ポートピアホテル(神戸市)
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] 破骨細胞の分化に必須な因子NFATc1の転写活性を抑制するアルクチゲニンの作用メカニズム

    • Author(s)
      山下照仁,李峰,上原俊介,小林泰浩,宇田川信之,門田重利,高橋直之
    • Organizer
      松本歯科大学学会
    • Place of Presentation
      松本歯科大学(塩尻市)
    • Data Source
      KAKENHI-PROJECT-24592821
  • [Presentation] TRAP marks as vestiges of polarized osteoclasts.

    • Author(s)
      Naoyuki Takahashi
    • Organizer
      6th International Symposium on the Biology of Tartrate Resistant Acid Phosphatase.
    • Place of Presentation
      Kobe Potopia hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253097
  • [Presentation] 破骨細胞はどのように骨を認識し極性化するか

    • Author(s)
      高橋直之
    • Organizer
      日本歯科理工学会・中部支部夏季セミナー
    • Place of Presentation
      赤倉ホテル(新潟県妙高市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659833
  • 1.  UDAGAWA Nobuyuki (70245801)
    # of Collaborated Projects: 35 results
    # of Collaborated Products: 0 results
  • 2.  SUDA Tatsuo (90014034)
    # of Collaborated Projects: 24 results
    # of Collaborated Products: 0 results
  • 3.  KOBAYASHI Yasuhiro (20264252)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 29 results
  • 4.  MIZOGUCHI Toshihide (90329475)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 15 results
  • 5.  MIYAURA Chisato (20138382)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 26 results
  • 6.  KATAGIRI Takenobu (80245802)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 7.  SHINKI Toshimasa (90138420)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 8.  SASAKI Takahisa (50129839)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 9.  NINOMIYA Tadashi (00360222)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 7 results
  • 10.  OZAWA Hidehiro (60018413)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 2 results
  • 11.  YAMASHITA Teruhito (90302893)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 25 results
  • 12.  NAKAMICHI Yuko (20350829)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 6 results
  • 13.  HOSOYA Akihiro (70350824)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 3 results
  • 14.  NAKAMURA Hiroaki (50227930)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 15.  JIMI Eijiro (40276598)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 16.  YAMAGUCHI Akira (00142430)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 17.  ABE Etsuko (70119147)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 18.  HIRAOKA Yukihiro (20097512)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 19.  TANAKA Hirofumi (30146899)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 20.  TAKITO Jiro (00197237)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 21.  UEHARA Shunsuke (90434480)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 22.  HE Jin Cheng (10205049)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 23.  YOSHIKI Shusaku (30085740)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 24.  OKUMURA Higeki (80350825)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 25.  KOIDE Masanori (10367617)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 26.  HIRAGA Tohru (70322170)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 27.  AKIYAMA Shuichi (70276591)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 28.  TAKAMI Masamichi (80307058)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 29.  KAWAKAMI Toshiyuki (80104892)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 30.  WANG Pao-li (20213613)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  SHUHUA Yang (80360220)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 32.  MIYAZAWA Hiroo (90147637)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 33.  NAMKAMURA Midori (90278177)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 34.  YAMAKI Mariko (90360221)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 35.  IMAMURA Yasuhiro (00339136)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 36.  KAWAHARA Ichiro (20319114)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 37.  Taguchi Akira (70243582)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 38.  IKEDA Tohru (00211029)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 39.  TAKAHASHI Masahiro (90340059)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 40.  UEMATSU Takashi (40203476)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 41.  FURUSAWA Kiyofumi (90165481)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 42.  MAYAHARA Mitsuori (30384184)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 43.  YUKITA Akira (80401214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  FUJINAMI Yoshiaki (80392801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  KAKUTA Saburou (40112726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  KUDO Ichiro (30134612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  KAMIJO Ryutaro (70233939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  MORIMURA Naoko (00349044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  KAWAGUCHI Hiroshi (40282660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  NAKAMURA Hiroshi (00278178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  SAHARA Noriyuki (70064699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  KURIHARA Saburo (70126225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  OKAFUJI Norimasa (50194379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  UEMATSU Setsuo (80271378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  星 和人 (30344451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  横瀬 敏志 (90245803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  深沢 加代子 (60064698)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  伊藤 雅波 (10349045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  石浦 美帆 (40327937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  南 康博 (70229772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 61.  荒 敏昭 (90387423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 62.  堀部 寛治 (70733509)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 63.  KADOTA Shigetoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 64.  KIKUCHI Takanobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  NISHITA MICHIRU
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 66.  YOKOO Tomotaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 67.  USUI Yuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 68.  KIM Yong jung
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 69.  ARAI Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 70.  山本 雅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 71.  安孫子 宜光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 72.  羽二生 久夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 73.  斎藤 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 74.  KIM YOONG AHM
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 75.  遠藤 守信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi