Tsuchida Junko 土田純子

Researcher Number	90769415
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 新潟大学, 医歯学総合病院, 特任助教 2019 – 2021: 新潟大学, 医歯学総合研究科, 客員研究員 2019 – 2020: 新潟大学, 医歯学総合病院, 専任助教 2017 – 2018: 新潟大学, 医歯学総合病院, 医員 2016: 新潟大学, 医歯学総合病院, レジデント
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Keywords	Principal Investigator 乳癌 / スフィンゴシン-1-リン酸 / 脂質メディエーター / 乳がん / 免疫チェックポイント阻害薬 / 相同組換え修復欠損 / トリプルネガティブ / 変異シグネチャー / 腫瘍関連免疫細胞 / スフィンゴシン-1リン酸 / 癌間質液 … More Except Principal Investigator … More スフィンゴシン-1-リン酸 / 乳癌 / 脂質メディエーター / スフィンゴシン－1－リン酸 / 治療 / スフィンゴシンキナーゼ1型 / スフィンゴシン‐1-リン酸 / mutational signature / 遺伝子パネル検査 / 塩基置換 / 固形癌 / 消化器癌 / バイオインフォマティクス / ターゲット遺伝子パネル検査 / 変異シグネチャー / トリプルネガティブ / TP53 / 腫瘍免疫微小環境 / 薬剤耐性 / トリプルネガティブ乳癌 / 癌代謝 / スフィンゴシン-１-リン酸 / スフィンゴシンキナーゼ１型 / スフィンゴシンー１ーリン酸 / 抗エストロゲン剤耐性株 / ホルモン療法 Less

トリプルネガティブ乳癌における変異シグネチャー解析の臨床病理学的意義の解明Principal Investigator
- Principal Investigator
  
  土田純子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Niigata University
トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明
- Principal Investigator
  
  永橋昌幸
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Hyogo Medical University
Establishment of classification for base substitution pattern and assessment for clinical implication of mutational signature in solid tumors
- Principal Investigator
  
  Hirose Yuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Niigata University
The role of S1P for Tumor immune microenvironment in human breast cancerPrincipal Investigator
- Principal Investigator
  
  Tsuchida Junko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Niigata University
The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic application
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
  Niigata University
Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancer
- Principal Investigator
  
  Nagahashi Masayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
Elucidation of molecular mechanisms of a lipid mediator in resistance of breast cancer hormone therapy and its clinical significance
- Principal Investigator
  
  Ikarashi Mayuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Niigata University
The role of sphingosine-1-phosphate in interstitial fluid promoting the breast cancer progressionPrincipal Investigator
- Principal Investigator
  
  Tsuchida Junko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Niigata University

All 2023 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients2023
- Author(s)
  Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
- Journal Title
  
  Breast Cancer
  
  Volume: - Issue: 4 Pages: 584-595
- DOI
  10.1007/s12282-023-01449-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19522, KAKENHI-PROJECT-21K17850
[Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021
- Author(s)
  Ikarashi Mayuko、Tsuchida Junko、Nagahashi Masayuki、Takeuchi Shiho、Moro Kazuki、Toshikawa Chie、Abe Shun、Ichikawa Hiroshi、Shimada Yoshifumi、Sakata Jun、Koyama Yu、Sato Nobuaki、Hait Nitai C.、Ling Yiwei、Okuda Shujiro、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13367-13367
- DOI
  10.3390/ijms222413367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714, KAKENHI-PROJECT-21K17850
[Journal Article] Sphingosine Kinase 1 is Associated With Immune Cell Related Gene Expressions in Human Breast Cancer2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Masato Nakajima, Eriko Katsuta, Omar M. Rashid, Qianya Qi, Li Yan, Shujiro Okuda, Kazuaki Takabe, Toshifumi Wakai
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 15 Pages: 645-656
- DOI
  10.1016/j.jss.2020.06.057
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18049, KAKENHI-PROJECT-19H03714
[Journal Article] Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis2018
- Author(s)
  Nagahashi Masayuki、Yamada Akimitsu、Katsuta Eriko、Aoyagi Tomoyoshi、Huang Wei-Ching、Terracina Krista P.、Hait Nitai C.、Allegood Jeremy C.、Tsuchida Junko、Yuza Kizuki、Nakajima Masato、Abe Manabu、Sakimura Kenji、Milstien Sheldon、Wakai Toshifumi、Spiegel Sarah、Takabe Kazuaki
- Journal Title
  
  Cancer Research
  
  Volume: 78 Issue: 7 Pages: 1713-1725
- DOI
  10.1158/0008-5472.can-17-1423
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-16K19888
[Journal Article] Ceramide species are elevated in human breast cancer and are associated with less aggressiveness.2018
- Author(s)
  Moro K，Kawaguchi T，Tsuchida J，Gabriel E，Qi Q，Yan L，Wakai T，Takabe K，Nagahashi M
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 28 Pages: 19874-19890
- DOI
  10.18632/oncotarget.24903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19888
[Journal Article] Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer2017
- Author(s)
  Tsuchida Junko、Nagahashi Masayuki、Takabe Kazuaki、Wakai Toshifumi
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2017 Pages: 1-9
- DOI
  10.1155/2017/2076239
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888, KAKENHI-PROJECT-15H05676
[Journal Article] Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.2016
- Author(s)
  Nagahashi M, Yamada A, Miyazaki H, Allegood JC, Tsuchida J, Aoyagi T, Huang WC, Terracina KP, Adams BJ, Rashid OM, Milstien S, Wakai T, Spiegel S, Takabe K.
- Journal Title
  
  J Mammary Gland Biol Neoplasia
  
  Volume: 21 Issue: 1-2 Pages: 9-17
- DOI
  10.1007/s10911-016-9354-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04927, KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19055, KAKENHI-PROJECT-16K19888
[Journal Article] High levels of sphingolipids in human breast cancer2016
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Hasegawa M, Tatsuda K, Woelfel IA, Takabe K, Wakai T
- Journal Title
  
  J Surg Res
  
  Volume: 204 Issue: 2 Pages: 435-444
- DOI
  10.1016/j.jss.2016.05.022
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19888
[Journal Article] Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis2016
- Author(s)
  Tsuchida J, Nagahashi M, Nakajima M, Moro K, Tatsuda K, Ramanathan R, Takabe K, Wakai T
- Journal Title
  
  J Surg Res
  
  Volume: 205 Issue: 1 Pages: 85-94
- DOI
  10.1016/j.jss.2016.06.022
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05676, KAKENHI-PROJECT-16K19888
[Presentation] Correlation of mutational signature between whole genome sequencing and gene panel tests in colorectal cancer2023
- Author(s)
  廣瀬雄己，島田能史，田島陽介，阿部　馨，松本瑛生，大関　瑛，土田純子，諸　和樹，宗岡悠介，市川　寛，竹内志穂，永橋昌幸，坂田　純，奥田修二郎，若井俊文
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08750
[Presentation] 肥満状態下の乳癌転移におけるスフィンゴシン-1-リン酸の役割2021
- Author(s)
  永橋　昌幸，土田　純子，諸　和樹，長谷川　遙，小幡　泰生，遠藤　麻巳子，利川　千絵，五十嵐　麻由子，小山　諭，高部　和明，若井　俊文
- Organizer
  第29回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] Involvement of Sphingosine-1-phosphate in the Tumor Immune Microenvironment of Breast Cancer Patients2020
- Author(s)
  J. Tsuchida, M. Nagahashi, M. Ikarashi, K. Moro, C. Toshikawa, K. Miura, H. Ichikawa, T. Hanyu, K. Takizawa, Y. Shimada, T. Ishikawa, J. Sakata, H. Kameyama, T. Kobayashi, K. Takabe, T. Wakai
- Organizer
  2020 Academic Surgical Congress
- Data Source
  KAKENHI-PROJECT-19K18049
[Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Association between estrogen receptor status and plasma S1P levels in breast cancer patients2020
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020
- Author(s)
  永橋　昌幸，土田　純子，油座　築，諸　和樹，根本　万里子，廣瀬　雄己，利川　千絵，五十嵐　麻由子，三浦　宏平，市川　寛，羽入　隆晃，滝沢　一泰，中島　真人，島田　能史，小林　隆，坂田　純，石川　卓，亀山　仁史，若井　俊文
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03714
[Presentation] 乳癌微小環境における組織間質液中のスフィンゴリン脂質定量の試み2020
- Author(s)
  永橋昌幸，土田純子，諸　和樹，遠藤麻巳子，庭野稔之，山浦久美子，利川千絵，長谷川美樹，五十嵐麻由子，中島真人，小山　諭，高部和明，若井俊文
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Association between estrogen receptor status and plasma S1P levels in breast cancer patients2020
- Author(s)
  Masayuki Nagahashi, Junko Tsuchida, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 15th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 乳癌腫瘍免疫微小環境におけるスフィンゴシン-1-リン酸の役割の検討2020
- Author(s)
  土田純子，永橋昌幸，諸和樹，遠藤麻巳子，庭野稔之，山浦久美子，利川千絵，長谷川美樹，五十嵐麻由子，中島真人，小山諭，高部和明，若井俊文
- Organizer
  第28回　日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K18049
[Presentation] 血漿スフィンゴシン-1リン酸濃度は乳癌のリンパ節転移に関連する2019
- Author(s)
  土田　純子，永橋　昌幸，諸　和樹，遠藤　麻巳子，利川　千絵，五十嵐　麻由子，小山　諭，三浦　要平，油座　築，安藤　拓也，廣瀬　雄己，三浦　宏平，田島　陽介，市川　寛，島田　能史，坂田　純，小林　隆，亀山　仁史，高部　和明，若井　俊文
- Organizer
  第17回日本臨床腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-19K18049
[Presentation] Levels of sphingolipids in plasma are elevated in breast cancer patients with lymph node metastasis2019
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Mayuko Ikarashi, Yu Koyama, Hiroshi Ichikawa, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] Levels of sphingolipids in plasma are elevated in breast cancer patients with lymph node metastasis2019
- Author(s)
  Junko Tsuchida, Masayuki Nagahashi, Kazuki Moro, Mayuko Ikarashi, Yu Koyama, Jun Sakata, Takashi Kobayashi, Hitoshi Kameyama, Kazuaki Takabe, Toshifumi Wakai
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Sphingosine-1-phospate Signaling Regulates Drug Resistance Mediated by Glutathione2019
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 乳癌患者における血漿中スフィンゴシン-1-リン酸濃度の臨床的意義2019
- Author(s)
  五十嵐　麻由子，永橋　昌幸，土田　純子，遠藤　麻巳子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，中島　真人，小山　諭，若井　俊文
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Sphingosine-1-phospate signaling regulates drug resistance mediated by glutathione2019
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Ikarashi M, Nakajima M, Abe M, Saito T, Komatsu M, Soga T, Takabe K, Sakimura K, Wakai T
- Organizer
  The 14th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Sphingosine-1-phosphate Affects Tumor-associated Immune Cells in Human Breast Cancer Patients2018
- Author(s)
  Junko Tsuchida，Masayuki. Nagahashi，Kazuki. Moro，Ayaka Otani，Maiko Endo，Mayuko Ikarashi，Masato Nakajima，Yu Koyama，Jun Sakata，Takashi Kobayashi，Hitoshi Kameyama，Qianya Qi，Li Yan，Kazuaki Takabe，Toshifumi Wakai
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] The Roles of Sphingosine-1-phosphate Produced by Sphingosine Kinases in Tumor and Its Microenvironment2018
- Author(s)
  Kohei Miura，Masayuki Nagahashi，Masato Nakajima，Kizuki. Yuza，Junko Tsuchida，Yuki Hirose，Manabu Abe，Kenji Sakimura，Toshifumi Wakai
- Organizer
  13th Annual Academic Surgical Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 肥満が引き起こす慢性炎症による乳癌の転移促進と脂質メディエーターの役割2018
- Author(s)
  永橋　昌幸，土田　純子，油座　築，中島　真人，高部　和明，若井　俊文
- Organizer
  第25回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 肥満が引き起こす慢性炎症による乳癌の転移促進と脂質メディエーターの役割2018
- Author(s)
  永橋　昌幸，土田　純子，油座　築，中島　真人，高部　和明，若井　俊文
- Organizer
  第25回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Tumor mutation burden in triple negative breast cancer patients in Japan2018
- Author(s)
  Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T
- Organizer
  2018 American Society of Clinical Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] Obesity-induced sphingosine-1-phosphate in tumor interstitial fluid promotes angiogenesis and breast cancer progression2018
- Author(s)
  Nagahashi M, Tsuchida J, Moro K, Yuza K, Hirose Y, Ikarashi M, Sakata J, Kobayashi T, Kameyama H, Wakai T, Takabe K
- Organizer
  第１５回臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] ヒト乳癌組織では全てのCeramide主合成経路が活性化されている2018
- Author(s)
  諸　和樹，永橋　昌幸，遠藤　麻巳子，大溪　彩香，土田　純子，庭野　稔之，山浦　久美子，長谷川　美樹，利川　千絵，五十嵐　麻由子，中島　真人，廣瀬雄己，坂田　　純，亀山　仁史，小林　隆，川口　耕，高部　和明，若井　俊文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] シンポジウム 5　ゲノム医療推進に向けた取り組みの課題と展望　当科におけるゲノム医療推進に向けた取組み2018
- Author(s)
  永橋　昌幸，土田　純子，遠藤　麻巳子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，神林　智寿子，金子　耕司，佐藤　信昭，若井　俊文
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19576
[Presentation] 乳癌細胞の代謝動態におけるスフィンゴシン-1-リン酸産生酵素の働き2017
- Author(s)
  永橋昌幸，中島真人，土田純子，諸　和樹，遠藤麻巳子，大渓彩香，庭野稔之，辰田久美子，長谷川美樹，利川千絵，五十嵐麻由子，坂田　純，亀山仁史，小林　隆，高部和明，斎藤哲也，小松雅明，曽我朋義，小山　諭，若井俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] The levels of Sphingosine-1-phosphate and its related gene expressions in breast cancer patients2017
- Author(s)
  Junko Tsuchida，Masayuki Nagahashi，Masato Nakajima，Kazuaki Takabe，Toshifumi Wakai
- Organizer
  2017 San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] CRISPR/Cas9 によるスフィンゴシン-1-リン酸産生酵素の乳癌発育進展における役割解明2017
- Author(s)
  三浦　要平，中島　真人，永橋　昌幸，安藤　拓也，油座　築，土田　純子，田島　陽介，坂田　純，小林　隆，亀山　仁史，阿部　学，﨑村　建司，若井　俊文
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 乳癌患者における腫瘍のスフィンゴシン-1-リン酸産生と腫瘍関連免疫細胞に対する役割2017
- Author(s)
  土田　純子，永橋　昌幸，中島真人，高部　和明，若井　俊文
- Organizer
  第24回外科侵襲とサイトカイン研究会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] Peri-tumor Sphingosine-1-phosphate Levels Are Affected by the Tumor2017
- Author(s)
  Tsuchida J, Moro K, Ohtani A, Endo M,Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Nakajima M, Y. Koyama Ｙ, Sakata J, Kobayashi T, Kameyama H, Takabe K, Wakai T, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 乳がんのがん細胞と宿主におけるスフィンゴシン-1-リン酸産生酵素の機能解析2017
- Author(s)
  中島　真人，永橋　昌幸，大谷　彩香，遠藤　麻已子，土田　純子，諸　和樹，庭野　稔之，山浦　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，坂田　純，亀山　仁史，小林　隆，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] Sphingosine-1-phosphate and tumor-associated immune cells in the tumor microenvironment2017
- Author(s)
  Junko Tsuchida，Masayuki Nagahashi，Masato Nakajima，Kazuaki Takabe，Toshifumi Wakai
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] Sphingosine-1-phosphate affects tumor-associated immune cells in human breast cancer patients2017
- Author(s)
  Tsuchida J, Nagahashi M, Moro K, Otani A, Endo M, Ikarashi M, Nakajima M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Yan Q, Yan L, Takabe K, Wakai T
- Organizer
  The 13th Annual Academic Surgical Congress
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] シンポジウム15 私たちが日本で行うべき乳癌研究　基礎から臨床まで日本だからこそできるトランスレーショナルリサーチの実践を目指して2017
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，高部　和明，若井　俊文
- Organizer
  第25回日本乳癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10538
[Presentation] 乳がん患者における脂質メディエーター・スフィンゴシン-１-リン酸の定量と臨床的意義2017
- Author(s)
  土田　純子，永橋　昌幸，遠藤　麻巳子，大溪　彩香，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，坂田　純，小林　隆，亀山　仁史，高部　和明，若井　俊文
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] Obesity-induced Sphingosine-1-phosphate in Breast Cancer Interstitial Fluid Promotes Angiogenesis2017
- Author(s)
  Tsuchida J, Nakajima M, Moro K, Ohtani A, Endo M, Niwano T, Tatsuda K, Toshikawa C, Hasegawa M, Ikarashi M, Koyama Y, Sakata J, Kobayashi T, Kameyama H, Wakai T, Takabe K, Nagahashi M
- Organizer
  The 12th Annual Academic Surgical Congress
- Place of Presentation
  Las Vegas, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 乳がん手術検体におけるスフィンゴリン脂質の定量2016
- Author(s)
  中島　真人，永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，小山　諭，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト(東京都江東区)
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 肥満によって促進される乳癌の血管新生に対する抗スフィンゴシン-1-リン酸受容体治療2016
- Author(s)
  永橋　昌幸，大渓　彩香，遠藤　麻巳子，土田　純子，諸　和樹，庭野　稔之，辰田　久美子，利川　千絵，長谷川　美樹，五十嵐　麻由子，中島　真人，小山　諭，山田　顕光，青柳　智義，高部　和明，若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト(東京都江東区)
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 乳がん患者における腫瘍内スフィンゴシン-1-リン酸濃度と臨床病理学的因子の関連について2016
- Author(s)
  土田　純子、永橋　昌幸、遠藤　麻巳子、大溪　彩香、庭野　稔之、辰田　久美子、利川　千絵、長谷川　美樹、五十嵐　麻由子、中島　真人、小山　諭、高部　和明、若井　俊文
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビックサイト(東京都江東区)
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] Roles of sphingosine-1-phosphate produced by sphingosine kinases in cancer progression2016
- Author(s)
  Masato Nakajima, Masayuki Nagahashi, Junko Tsuchida, Toshifumi Wakai
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Data Source
  KAKENHI-PROJECT-16K19888
[Presentation] 肥満を伴う乳癌患者における血清スフィンゴシン-1-リン酸の定量2016
- Author(s)
  土田　純子、永橋　昌幸、遠藤　麻巳子、大溪　彩香、庭野　稔之、辰田　久美子、利川　千絵、長谷川　美樹、五十嵐　麻由子、小山　諭、高部　和明、若井　俊文
- Organizer
  第78回臨床外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪(東京都港区)
- Data Source
  KAKENHI-PROJECT-16K19888

1. Nagahashi Masayuki (30743918)

# of Collaborated Projects: 6 results

# of Collaborated Products: 26 results
2. 若井俊文 (50372470)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. 奥田修二郎 (00512310)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. 阿部学 (10334674)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. 諸和樹 (10745566)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. 五十嵐道弘 (50193173)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. 崎村建司 (40162325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 島田能史 (20706460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 内田遥 (80962795)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Ikarashi Mayuko (50790284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
11. Hirose Yuki (10737365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 小山諭 (10323966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. 三好康雄 (50283784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 遠藤麻巳子 (20915227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 凌一葦 (70804540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 利川千絵 (80745563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 須貝美佳 (10772030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小幡泰生 (00978702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 竹内志穂 (70422277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 市川寛 (50721875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 坂田純 (70447605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. Takabe Kazuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuchida Junko 土田 純子

Research Projects

Research Products

Co-Researchers

トリプルネガティブ乳癌における変異シグネチャー解析の臨床病理学的意義の解明Principal Investigator

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トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明

Principal Investigator

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Establishment of classification for base substitution pattern and assessment for clinical implication of mutational signature in solid tumors

Principal Investigator

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Review Section

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The role of S1P for Tumor immune microenvironment in human breast cancerPrincipal Investigator

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The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic application

Principal Investigator

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Mechanisms of cancer metabolism and drug resistance regulated by S1P in triple negative breast cancer

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Elucidation of molecular mechanisms of a lipid mediator in resistance of breast cancer hormone therapy and its clinical significance

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The role of sphingosine-1-phosphate in interstitial fluid promoting the breast cancer progressionPrincipal Investigator

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[Journal Article] Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients2023

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[Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021

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[Journal Article] Sphingosine Kinase 1 is Associated With Immune Cell Related Gene Expressions in Human Breast Cancer2020

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[Journal Article] Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis2018

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[Journal Article] Ceramide species are elevated in human breast cancer and are associated with less aggressiveness.2018

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[Journal Article] Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer2017

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Tsuchida Junko 土田純子