HAKOSHIMA Toshio 箱嶋敏雄

… Alternative Names

箱嶋敏雄ハコシマトシオ

HAKOSHIMA. Toshio 箱嶋敏雄

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Researcher Number	00164773
Other IDs
Affiliation (Current)	2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 教授
Affiliation (based on the past Project Information) *help	2009 – 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 2007 – 2011: Nara Institute of Science and Technology, 情報科学研究科, 教授 2002 – 2005: Nara Inst. Of Sci. and Tech. Structural Biology Lab. Prof., 情報科学研究科, 教授 1994 – 2002: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 2001: 奈良先端科学技術力学院大学, バイオサイエンス研究科, 教授 … More 2000: 奈良先端科学大学院大学, バイオサイエン研究科, 教授 1998: Nara Advanced Institute of Science and Technology, Professor, バイオサイセンス研究科, 教授 1998: 奈良先端科学技術大学院大学, バイオサンエンス研究科, 教授 1995 – 1997: 奈良先端大学院大学, バイオサイエンス科, 教授 1993: 大阪大学, 薬学部, 助教授 1989 – 1992: 大阪大学, 薬学部, 助手 1986 – 1987: 大阪大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biophysics / Structural biochemistry / 広領域 / Biological Sciences Except Principal Investigator Biological Sciences / Structural biochemistry / 分子遺伝学・分子生理学 / Physical pharmacy / 生物物性学 / Biophysics
Keywords	Principal Investigator 構造生物学 / X線 / 複合体 / DNA / 分子認識 / タンパク質 / 生物物理学 / 細胞生物学 / 蛋白質 / structural biology … More / molecular complex / protein / 相互作用 / 分子生物学 / 生化学 / 細胞骨格 / 細胞接着 / シグナル伝達 / 転写制御 / 結晶 / X-ray / X線結晶学 / 転写因子 / 二成分系 / 結晶化 / DNA結合蛋白質 / 高次構造 / 三次元構造 / TRAF / IRE / ICAM-2 / Rho / G protein / signal transduction / transcription / イメージングプレート / 構造変化 / 分子構造 / 植物ホルモン / 浸潤 / 転移 / マグネシウムイオン / 構造転移 / 塩基配列特異性 / DNA構造 / 蛋白質構造 / 軸索 / 神経 / 構造 / 制御機構 / 分子細胞生物学 / purification / separation / stress / IRF / 精製 / 分離 / ストレス / adhesion molecules / cytoskeleton / PTP2 / PIP2 / ミラー / 光学系 / 回折 / 微小結晶 / G蛋白質 / 蛋白質-DNA / molecular recognition / molecular / protein crystallography / X-ray optics / X-ray detector / imaging palate / 巨大複合体 / 回転対陰極 / X線発生装置 / データ収集法 / 高輝度 / 複合体結晶 / 高輝度X線 / 検出器 / basic transcription factor / transcription factor / 認識 / ピロモータ / σ因子 / 大腸菌 / 基本転写因子 / エネルギー移動 / 分子構造変化 / メカノバイオロジー / 蛍光 / タンパク質工学 / 張力 / 受容体 / 密着結合 / unconventionalミオシン / Gタンパク質 / 電子顕微鏡 / NMR / 翻訳後修飾 / 接着分子 / 足場形成 / GEF / 膜裏打ち / アクチン / 微小管 / +TIP / Rhoキナーゼ / がん / CLASP / APC / EB1 / チューブリン / CLIP-170 / アダプタータンパク質 / 膜タンパク質 / ERM / NEP / アロステリック / ジストニア / 金属 / X線結晶構造解析 / 抗酸化蛋白質 / ヘム / 酸化還元 / 配位結合 / カリウムイオン / 塩基配列 / DNA結合モチーフ / bHLH / bZIP / 加水分解 / 分子スウィッチ / GTP結合蛋白質 / 結晶構造 / ヒスチジンキナーゼ / Hptドメイン / 多段階リン酸リレー / 細胞内情報伝達 / 融合蛋白質 / DNA複製 / センサー蛋白質 / ヘム蛋白質 / リン酸化 / 亜鉛イオン / DNAの構造 / 蛋白質の構造 / 構造解析 / 結晶学 / 反応機構 / 酵素 / ケイジ化合物 / リボヌクレアーゼ / 特異性 … More Except Principal Investigator NMR / X線結晶構造解析 / 構造生物学 / DNA / 分子生物学 / 高次構造 / DNA結合蛋白質 / 重点領域研究 / 分子認識 / タンパク質 / 転写因子 / RNA / 構造解析 / 生物物理学 / CD / Merlin / Rho / Grb2 / SH3 / Vav / RNAポリメラーゼ / X線構造解析 / 蛋白質 / base mismatch / X-Ray determination / Cis-Pt-DNA complex / Molecular dynamic simulation / Proton NMR / DNA structure / 抗生物質の作用メカニズム / 塩基配列特異性 / 円二色性 / 核酸のコンフォメーション / Bent構造 / 塩基対ミスマッチ / X-ray / シス白金-DNA / 分子動力学計算 / プロトンNMR / DNAの高次構造 / Dynamics of DNA / Structure of bulge loop / Structure of hairpin loop / cro repressor / HU protein / Structure and function of tRNA / Structures of DNA / Hu-DNA複合体 / Croリプレッサー / ヘアピンループ / 制限酵素 / tRNA / X線回析 / DNAの分子運動 / バルジループの構造 / Cro蛋白質ヘアピンループの構造 / Hu蛋白質 / tRNAの構造と機能 / DNA構造の多形 / FERM domain / ERM protein / tertiary structure / X-ray analysis / auto-inhibition / Rho-signalling / Rho-kinase / DHドメイン / コイルドコイル / Rho-キナーゼ / FERMドメイン / ERMタンパク質 / 立体構造 / 自己阻害 / Rhoシグナリング / Rhoキナーゼ / tertiary structure IP3 / praline rich region / Neurop / PB2 / PBI / 好中級活性酸素発生系 / タイトジャンクション / N-WASP / 多核体病ウィルス / バキュロウィルス / Grb2-cSH3 / PRR / Vav-nSH3 / PTB様ドメイン / IP3 / radixin / 蛋白質立体構造 / PRR領域 / transfer activation / reorganization / transfer extension reaction / transcription initiation / functional mechanism / inter-transcriptional interaction / transcriptional cofactor / transcription factor / ノックアウトマウス / 転写調節因子 / TF II H / TF II E / TF II D / コアクチベータ- / 基本転写装置 / CREB / STAT3 / Ah受容体 / DSIF / コアクチベーター / TFIID / TFIIE / TFIIH / 相互作用 / DNA結合能 / スプライシング / リン酸化 / 転写開始複合体 / 転写活性化 / 再構成 / 転写伸長反応 / 転写開始 / 作用機構 / 転写因子間相互作用 / 転写共役因子 / Molecular Biology / RNA-binding Proteins / DNA-binding Proteins / Transcription Factors / X-ray Crystallography / Structural Biology / X線結晶 / ERA / ペプチド鎖解離因子 / ロイシンレギュロン / リジルtRNA合成酵素 / 翻訳 / 転写後制御 / 遺伝子発現 / Amino acid Sequence of heavy chain in Fab / surface protein / Monoclonal antibodies against circumsporozoite / Circumsporozoite surface protein as antigen / Repeating amino acid sequence / X-ray structural studies / Malaria vaccine / 抗原・抗体複合体 / モノクロ-ナル抗体 / 融合蛋白質抗原 / マラリア原虫表皮蛋白質 / H鎖アミノ酸配列 / 抗原・抗体および抗原・抗体複合体の結晶化 / モノクロ-ナル抗体Fab / マラリア原虫表皮蛋白質抗原 / マラリアワクチン / TTL / チューブリン / 微小管 / チューブリンチロシンリガーゼ / シグナル伝達 / ペルオキシレドキシン / PCNA / flap endonuclease-1 / 構造機能相関 / 分子解剖 / 転写制御 / 転写装置 / NMR装置 / 核磁気共鳴 / X線回折 / 蛋白質-核酸相互作用 / 制御蛋白質 / 機能発現 / RNA結合蛋白質 / 制御RNAシグナル / RNAプロセシング / 翻訳制御 / 転写後調節 / RNA触媒 / 核磁気共鳴装置 / 分子構造 / 多次元NMR / 結晶解析 / 放射光 / 識別機構 Less

Design of a new mechano-sensorPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA TOSHIO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Nara Institute of Science and Technology
Structural and physical properties of the clutch molecular complex in motile cells.Principal Investigator
- Principal Investigator
  
  Hakoshima Toshio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nara Institute of Science and Technology
Structural studies on tubulin tyrosine ligase and its application.
- Principal Investigator
  
  MISHIMA Masaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo Metropolitan University
Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.Principal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Structural biology of animal and plant signaling proteinsPrincipal Investigator
- Principal Investigator
  
  Hakoshima Toshio
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Structural basis of cell-signalling complexes mediating signal perception, transduction and responsesArea Organizer
- Area Organizer
  
  HAKOSHIMA Toshio
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Nara Institute of Science and Technology
ユビキチン化シャペロンの基礎研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
癌細胞の浸潤・転移関連RacGEFと細胞接着分子の構造生物学Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
細胞膜足場形成の多次元複合体の構造生物学Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Structural bases of spliceosome indepemdent splicing
- Principal Investigator
  
  KOJIMA Chojiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nara Institute of Science and Technology
膜貫通型プロテアーゼの細胞骨格への連結の構造的基礎Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
微小管ダイナミックス制御の構造的基礎Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Structural biology of cytoskeletal control by dynamic protein complex formation.Principal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nara Institute of Science and Technology
Na+/H+交換輸送体複合体の構造と細胞膜・細胞骨格との相互作用
- Principal Investigator
  
  KOJIMA Chojiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
複製・修復のプラットホーム蛋白質の形成する複合体構造
- Principal Investigator
  
  北野健
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Structural studies of stress-responsive sensor protein kinasesPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
Structural basis for auto-inhibition mechanism of Rho-kinase
- Principal Investigator
  
  SHIMIZU Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Yokohama City University
X線結晶解析による金属蛋白質の構造生物化学Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
「Structural biology of the small G protein Rho by X-ray analyses of the molecular complexes」Principal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  NARA INSTITUTE OF SCIENCE AND TECHNOLOGY
ヘム結合性抗酸化蛋白質HBP23の結晶構造解析Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
蛋白質のスウッチ機能における金属の生物構造化学Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
Protein-protein interaction in intracellular signal transduction
- Principal Investigator
  
  INAGAKI Fuyuhiko
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
  Tokyo Metropolitan Organization for Medical Research
In-house X-ray intensity data-collection system for macromolecular complex crystalsPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  広領域
- Research Institution
  Nara Institute of Science and Technology
情報伝達と遺伝子発現における生体金属の構造学的研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
L-Mafを中心とした転写因子のX線構造生物学的研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms of functional expression of transcription regulation factors through their interaction with coactivators or corepressors
- Principal Investigator
  
  FUJII-KURIYAMA Yoshiaki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
Structural Studies of Molecular Recognition by Proteins : X-ray Analyses of Complex CrystalsPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Nara Institute of Science and Technology
嫌気的条件センサー蛋白質の結晶学的研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
複製関連調節因子DREF・DNA複合体のX線構造解析Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
リン酸化による蛋白質の機能制御に関する構造生物学的研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Nara Institute of Science and Technology
Structural Studies on Molecular Recognition of Nucleic Acid BasesPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Nara Institute of Science and Technology
Development of X-ray intensity data-collection system for macromolecular crystalsPrincipal Investigator
- Principal Investigator
  
  HAKOSHIMA Toshio
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Nara Institute of Science and Technology
繰返し配列DNAを認識する制御蛋白質の高次構造研究Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nara Institute of Science and Technology
Roles of Protein Structures on the DNA Recognition
- Principal Investigator
  
  NISHIMURA Yoshifumi
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
DNAの高次構造を識別する蛋白質(まとめ)
- Principal Investigator
  
  京極好正
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Laue法のためのRNaseT1/ケイジ化ヌクレオチド複合体の結晶化Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
構造転移を伴った会合及びDNA塩基配列の認識をする制御蛋白質の立体構造Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
蛋白質/DNA複合体の構造Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
転写装置の分子解剖推進のための調査研究
- Principal Investigator
  
  石浜明
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  National Institute of Genetics
翻訳アクティベーター蛋白質と制御RNAの研究
- Principal Investigator
  
  中村義一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
蛋白質/DNA複合体の構造Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
DNAの高次講造を識別する蛋白質
- Principal Investigator
  
  京極好正
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
RNAの動的機能発現の分子機構
- Principal Investigator
  
  中村義一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
蛋白質/DNA複合体の構造Principal Investigator
- Principal Investigator
  
  箱嶋敏雄
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
DNAの高次構造を識別する蛋白質
- Principal Investigator
  
  京極好正
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
DNAの高次構造を識別する蛋白質
- Principal Investigator
  
  KYOGOKU Yoshimasa
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Osaka University
X-ray Structural Studies of Antigen-Antibody Complex Toward Malaria Vaccine Development.
- Principal Investigator
  
  TOMITA Ken-ichi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
Versatality of Nucleic Acid Structure and its recognition
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Tokyo College of Pharmacy
Structual Studies for Nucleic Acids Conformation as Genetic Signal and Regulational Signal
- Principal Investigator
  
  FUJII SATOSHI
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  FACULTY OF PHARMACEUTICAL SCIENCES, OSAKA UNIVERSITY

[Book] Protein modification for crystallization. in Advanced Methods in Structural Biology (eds T. Senda, K. Maenaka)2016
- Author(s)
  Hakoshima, T.
- Total Pages
  340
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26251006
[Book] Protein modification for crystallization. in Advanced Methods in Structural Biology (eds T. Senda, K. Maenaka)2016
- Author(s)
  Hakoshima, T
- Total Pages
  340
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26650022
[Book] Nature Encyclopedia of the Human Geneme, Vol.32003
- Author(s)
  T.Hakoshima
- Total Pages
  1023
- Publisher
  Nature Pub. Group
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis. Proc. Natl.2018
- Author(s)
  Abe, K., Katsuno, H., Toriyama, M., Baba, K., Mori, T., Hakoshima, T., Kanemura, Y., Watanabe, R. and Inagaki, N.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 115 Issue: 11 Pages: 2764-2769
- DOI
  10.1073/pnas.1711667115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102010, KAKENHI-PROJECT-17H05003
[Journal Article] The force‐sensing device region of α‐catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form2018
- Author(s)
  Hirano, Y., Amano, Y., Yonemura, S. and Hakoshima, T.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 5 Pages: 16-16
- DOI
  10.1111/gtc.12578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-17K07448
[Journal Article] Structural basis of thalidomide enantiomer binding to cereblon.2018
- Author(s)
  Mori, T., Itoh, T., Liu, S., Ando, H., Sakamoto, S., Yamaguchi, Y., Tokunaga, E., Shibata, N., Handa, H. and Hakoshima, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1294-1294
- DOI
  10.1038/s41598-018-19202-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-15H04288, KAKENHI-PROJECT-17H04213, KAKENHI-PROJECT-17H06112
[Journal Article] Real-time TIRF observation of vinculin recruitment to stretched α-catenin by AFM.2018
- Author(s)
  Maki, K., Han, S. -U., Hirano, Y., Yonemura, S. Hakoshima, T. and Adachi, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1575-1575
- DOI
  10.1038/s41598-018-20115-8
- NAID
  120006517895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-17J03032
[Journal Article] Efficient expression of SRK intracellular domain by a modeling-based protein engineering.2016
- Author(s)
  Murase K, Hirano Y, Takayama S, Hakoshima T.
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 印刷中 Pages: 70-75
- DOI
  10.1016/j.pep.2015.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440025, KAKENHI-PLANNED-22121002, KAKENHI-PLANNED-23113002, KAKENHI-PROJECT-25252021, KAKENHI-PLANNED-16H06467, KAKENHI-PROJECT-15K18683, KAKENHI-PROJECT-16H06380
[Journal Article] Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway2016
- Author(s)
  Sun-Yong Kim, Yuka Tachioka, Tomoyuki Mori & Toshio Hakoshima
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 28488-28488
- DOI
  10.1038/srep28488
- NAID
  120005841618
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-26650022
[Journal Article] Mechano-adaptive sensory mechanism of α-catenin under tension2016
- Author(s)
  Koichiro Maki, Sung-Woong Han, Yoshinori Hirano, Shigenobu Yonemura, Toshio Hakoshima & Taiji Adachi
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 24878-24878
- DOI
  10.1038/srep24878
- NAID
  120006337976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-14J01854, KAKENHI-PROJECT-25440025, KAKENHI-PROJECT-15K13832, KAKENHI-PROJECT-26650022, KAKENHI-PROJECT-15KT0086
[Journal Article] Structure of the free form of the N-terminal VH1 domain of monomeric α-catenin.2015
- Author(s)
  Shibahara T, Hirano Y, Hakoshima T.
- Journal Title
  
  FEBS Letter
  
  Volume: 589 Issue: 15 Pages: 1754-1760
- DOI
  10.1016/j.febslet.2015.05.053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25440025, KAKENHI-PLANNED-22121002, KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-13J10057
[Journal Article] MT1-MMP recognition by ERM proteins and its implication in CD44 shedding.2015
- Author(s)
  Shin-ichi Terawaki, Ken Kitano, Miki Aoyama, Tomoyuki Mori, Toshio Hakoshima
- Journal Title
  
  Genes to Cells
  
  Volume: 20(10) Issue: 10 Pages: 847-859
- DOI
  10.1111/gtc.12276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25440024, KAKENHI-PROJECT-25840017, KAKENHI-PLANNED-22121002, KAKENHI-PROJECT-26251006
[Journal Article] Structures of D14 and D14L in the strigolactone and karrikin signaling pathways2013
- Author(s)
  Kagiyama M, Hirano Y, Mori T, Kim SY, Kyozuka J, Seto Y, Yamaguchi S, Hakoshima T
- Journal Title
  
  Genes Cells.
  
  Volume: 18 Issue: 2 Pages: 147-160
- DOI
  10.1111/gtc.12025
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22121002, KAKENHI-PROJECT-23770119, KAKENHI-PROJECT-24780117
[Journal Article] Structure of the RecQ C-terminal domain of human Bloom syndrome protein.2013
- Author(s)
  Kim SY, Hakoshima T, Kitano K.
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Issue: 1 Pages: 3294-3294
- DOI
  10.1038/srep03294
- NAID
  120005841622
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22121002, KAKENHI-PROJECT-23770118, KAKENHI-PROJECT-25440024
[Journal Article] Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR2013
- Author(s)
  Kanaba T, Maesaki R, Mori T, Ito Y, Hakoshima T, Mishima M.
- Journal Title
  
  Biochim. Biophys Acta.
  
  Volume: 1834(2) Pages: 499-507
- Data Source
  KAKENHI-PROJECT-23770124
[Journal Article] Microtubule-binding sites of the CH domain of EBl and its autoinhibition revealed by NMR.2013
- Author(s)
  Kanaba T, Maesaki R, Mori T, I to Y, Hakoshima T, Mishima M.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1834 Issue: 2 Pages: 499-507
- DOI
  10.1016/j.bbapap.2012.10.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40042, KAKENHI-PLANNED-22121002, KAKENHI-PUBLICLY-24121722, KAKENHI-PUBLICLY-25117723, KAKENHI-PROJECT-25650025
[Journal Article] Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism.2013
- Author(s)
  Nasuno R, Hirano Y, Itoh T, Hakoshima T, Hibi T, Takagi H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110 Issue: 29 Pages: 11821-11826
- DOI
  10.1073/pnas.1300558110
- NAID
  120005716836
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22121002, KAKENHI-PROJECT-23770119, KAKENHI-PROJECT-25440025
[Journal Article] ジベレリン受容体のジベレリン識別とエフェクター認識2010
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌 52
  
  Pages: 37-41
- NAID
  10026107815
- Data Source
  KAKENHI-PUBLICLY-21025021
[Journal Article] ジベレリン受容体のジベレリン識別とエフェクター認識2010
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌 52
  
  Pages: 37-41
- NAID
  10026107815
- Data Source
  KAKENHI-PROJECT-20011006
[Journal Article] ジベレリン受容体のジベレリン識別とエフェクター認識2010
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌 52
  
  Pages: 37-41
- NAID
  10026107815
- Data Source
  KAKENHI-PROJECT-20051017
[Journal Article] Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicalse WRN.2010
- Author(s)
  Kitano, K.Kim, S.Y., Hakoshima, T.
- Journal Title
  
  Structure (Cell Press). 18(2)
  
  Pages: 177-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-targeting module.2010
- Author(s)
  Terawaki, S., Kitano, K., Mori, T., Zhai, Y., Higuchi, Y., Itoh, N., Watanabe, T., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  EMBO J. 29(1)
  
  Pages: 236-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] ジベレリン受容体のジベレリン識別とエフェクター認識2010
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌
  
  Volume: 52 Pages: 37-41
- NAID
  10026107815
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.2010
- Author(s)
  Nishimura, A., Kitano, K., Takasaki, J., Taniguchi, M., Mizuno, M., Tago K., Hakoshima, T., Itoh, H.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 107(31)
  
  Pages: 13666-13671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicalse WRN2010
- Author(s)
  Kitano, K. Kim, S. Y., Hakoshima, T.
- Journal Title
  
  Structure (Cell Press) 18 (2)
  
  Pages: 177-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-targeting module2010
- Author(s)
  Terawaki, S., Kitano, K., Mori, T., Zhai, Y., Higuchi, Y., Itoh, N., Watanabe, T., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  EMBO J. 29 (1)
  
  Pages: 236-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] 植物によるジベレリンの感知とシグナル伝達2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  生物物理 49
  
  Pages: 200-201
- NAID
  10025975787
- Data Source
  KAKENHI-PUBLICLY-21025021
[Journal Article] 植物によるジベレリンの感知とシグナル伝達2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  生物物理
  
  Volume: 49 Pages: 200-201
- NAID
  10025975787
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] 植物によるジベレリンの感知とシグナル伝達2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  生物物理 49
  
  Pages: 200-201
- NAID
  10025975787
- Data Source
  KAKENHI-PROJECT-20051017
[Journal Article] ジベレリン受容体の構造と機能の解明:植物ホルモン識別と標的タンパク質認識の機構2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  細胞工学 28
  
  Pages: 162-163
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] ジベレリン受容体の構造と機能の解明:植物ホルモン識別と標的タンパク質認識の機構2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  細胞工学 28
  
  Pages: 162-163
- Data Source
  KAKENHI-PROJECT-20051017
[Journal Article] 植物によるジベレリンの感知とシグナル伝達2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  生物物理 49
  
  Pages: 200-201
- NAID
  10025975787
- Data Source
  KAKENHI-PROJECT-20011006
[Journal Article] ジベレリン受容体の構造と機能の解明 : 植物ホルモン識別と標的タンパク質認識の機構2009
- Author(s)
  箱嶋敏雄
- Journal Title
  
  細胞工学 28
  
  Pages: 162-163
- Data Source
  KAKENHI-PROJECT-19036014
[Journal Article] Gibberellin-induced DELLA recognition by the gibberellin receptor GID1 (Article)2008
- Author(s)
  Murase, K., Hirano, Y., Sun, T.-p., Hakoshima, T.
- Journal Title
  
  Nature 456 (7221)
  
  Pages: 459-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Gibberellin-induced DELLA recognition by the gibberellin receptor GID1 (Article).2008
- Author(s)
  Murase, K., Hirano, Y., Sun, T.-p., Hakoshima, T.
- Journal Title
  
  Nature 456(7221)
  
  Pages: 459-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.2008
- Author(s)
  Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., *Hakoshima, T.
- Journal Title
  
  J.Mol.Biol. 381(3)
  
  Pages: 634-644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] ジベレリン受容体の構造と機能の解明 : 植物ホルモン識別と標的タンパク質認識の機構2008
- Author(s)
  箱嶋敏雄
- Journal Title
  
  細胞工学 28
  
  Pages: 162-163
- Data Source
  KAKENHI-PROJECT-20011006
[Journal Article] Structural properties of the cytoplasmic tail of adhesion molecule CD44 and its binding to FERM proteins2008
- Author(s)
  Mori, T., Kitano, K., Fukami, Y., Terawaki, S., Hakoshima, T.
- Journal Title
  
  J. Biol. Chem 283 (43)
  
  Pages: 29602-29612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural properties of the cytoplasmic tail of adhesion molecule CD44 and its binding to FERM proteins.2008
- Author(s)
  Mori, T., itano, K., Fukami, Y., Terawaki, S., Hakoshima, T.
- Journal Title
  
  J.Biol.Chem. 283(43)
  
  Pages: 29602-29612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation.2008
- Author(s)
  Gohda, K., *Hakoshima, T.
- Journal Title
  
  Journal of Computer-aided Molecular Design 22(11)
  
  Pages: 789-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structure of SixA, a histidine protein phosphatase of the ArcB HPt domain in E. coli2007
- Author(s)
  Hakoshima, T.
- Journal Title
  
  Methods in Enzymology 422
  
  Pages: 288-304
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis for type II membrance protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex.2007
- Author(s)
  Terawaki, S., Kitano, K., Hakoshima, T.
- Journal Title
  
  J.Biol.Chem. 282(27)
  
  Pages: 19854-19861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structure of SixA, a histidine protein phosphatase of the ArcB HPt domain in E. coli.2007
- Author(s)
  Hakoshima, T.
- Journal Title
  
  Methods in Enzymology 422
  
  Pages: 288-304
- Data Source
  KAKENHI-PROJECT-19036014
[Journal Article] Structure of SixA, a histidine protein phosphatase of the ArcB HPt domain in E. coli.2007
- Author(s)
  Hakoshima, T.
- Journal Title
  
  Methods in Enzymology 422
  
  Pages: 288-304
- Data Source
  KAKENHI-PROJECT-19037017
[Journal Article] Chapter III.P-loop pliability of Rho-kinase for inhibitor binding. In2007
- Author(s)
  Gohda, K., Hakoshima, T.
- Journal Title
  
  Drug Design Research Perspectives (Nova Science Publishers, Inc.) (Review)
  
  Pages: 39-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis of PSGL-1 binding to ERM proteins.2007
- Author(s)
  Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
- Journal Title
  
  Genes to Cells 12(12)
  
  Pages: 1329-1338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its Autoinhibition2007
- Author(s)
  Mishima, M., Maesaki, R., Kasa, M., Watanabe, T., Fukata, M., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104 (25)
  
  Pages: 10346-10351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.2007
- Author(s)
  Mishima, M., Maesaki, R., Kasa, M., Watanabe, T., Fukata, M., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 104(25)
  
  Pages: 10346-10351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19207010
[Journal Article] Molecular mechanism for the regulation of Rho-kinase by dimerization and its inhibition by fasudil.2006
- Author(s)
  Yamaguchi, H., Kasa, M., Amano, M., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  Structure 14(3)
  
  Pages: 589-600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.2005
- Author(s)
  Hamada, K., Kato, M., Shimizu, T., Ihara, K., Mizuno, T., Hakoshima, T.
- Journal Title
  
  Genes to Cells 10(1)
  
  Pages: 1-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase.2005
- Author(s)
  Yanuar, A., Sakurai, S., Kitano, K., Hakoshima, T.
- Journal Title
  
  Acta Crystallogr F61(11)
  
  Pages: 978-980
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus.2005
- Author(s)
  Kitano, K., Kita, K., Hakoshima, T., Niimura, Y., Miki, K.
- Journal Title
  
  Proteins 59(3)
  
  Pages: 644-647
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Structural basis of recruitment of human flap endonuclease 1 to PCNA.2005
- Author(s)
  Sakurai, S., Kitano, K., Yamaguchi, H., Hamada, K., Okada, K., Fukuda, K., Uchida, M., Ohtsuka, E., Morioka, H., Hakoshima, T.
- Journal Title
  
  EMBO J. 24(4)
  
  Pages: 683-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Crystal structure of the inhibitory GTP Cyclohydrolase I and GFRP complex.2004
- Author(s)
  Hatakeyama, T., Maita, N., Okada, K., Hakoshima, T.
- Journal Title
  
  Pterins, Folates and Neurotransmitters in Molecular Medicine (SHS Gesellschaft fur klinische Ernahrung mbH)
  
  Pages: 16-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] 核酸分子認識とその機能を中心とした構造生物学2004
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌 46
  
  Pages: 201-208
- NAID
  10013129619
- Data Source
  KAKENHI-PROJECT-12147206
[Journal Article] 核酸分子認識とその機能を中心とした構造生物学2004
- Author(s)
  箱嶋敏雄
- Journal Title
  
  日本結晶学会誌 46
  
  Pages: 201-208
- NAID
  10013129619
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein.2004
- Author(s)
  Maita, N., Okada, K., Hatakeyama, K., Hakoshima, T.
- Journal Title
  
  J.Biol.Chem. 279(49)
  
  Pages: 51534-51540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Structural Biology of Nucleic-Acid Recognition and its Roles in Regulation of Protein Functions.2004
- Author(s)
  Hakoshima, T.
- Journal Title
  
  Nihon kessyo Gakkaishi 46
  
  Pages: 201-208
- NAID
  10013129619
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Leucine zippers.2003
- Author(s)
  Hakoshima, T.
- Journal Title
  
  Nature Encyclopedia of the Human Genome (Nature Pub.Group) Vol.3
  
  Pages: 679-683
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Structural basis of the Rho GTPase signaling.2003
- Author(s)
  T.Hakoshima
- Journal Title
  
  J. Biochem. (Tokyo) 134・3
  
  Pages: 327-331
- NAID
  10012057338
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase.2003
- Author(s)
  Shimizu, T., Ihara, K., Maesaki, R., Amano, M., Kaibuchi, K., Hakoshima, T.
- Journal Title
  
  J.Biol.Chem. 278(46)
  
  Pages: 46046-46051
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Preparation and crystallization of human flap endonuclease FEN-1 in complex with proliferating-cell nuclear antigen, PCNA.2003
- Author(s)
  Sakurai, S., Kitano, K., Okada, K., Hamada, K., Morioka, H., Hakoshima, T.
- Journal Title
  
  Acta Crystallogr. D59(5)
  
  Pages: 933-935
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Journal Article] Structural basis of the Rho GTPase signaling.2003
- Author(s)
  Hakoshima, T., Shimizu, T., Maesaki, R.
- Journal Title
  
  J.Biochem. (Tokyo) 134(3)
  
  Pages: 327-331
- NAID
  10012057338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370046
[Presentation] はじめに2013
- Author(s)
  箱嶋敏雄
- Organizer
  第 51 回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Data Source
  KAKENHI-ORGANIZER-22121001
[Presentation] 構造細胞生物学と創薬2013
- Author(s)
  箱嶋　敏雄
- Organizer
  創薬薬理フォーラム第21回シンポジウム
- Place of Presentation
  日本薬学会長井記念館 (東京都渋谷区)
- Year and Date
  2013-09-19
- Invited
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 構造細胞生物学の生物物理学的こころ2013
- Author(s)
  箱嶋敏雄
- Organizer
  第 51 回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Data Source
  KAKENHI-ORGANIZER-22121001
[Presentation] Crystallographic Studies of Werner Syndrome DNA Helicase2012
- Author(s)
  Ken Kitano, Sun-Yong Kim, Toshio Hakoshima
- Organizer
  Meeting of the American Crystallographic Association (ACA2012)
- Place of Presentation
  Westin Waterfront Hotel, Boston, USA
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] Transferred cross-saturation 法を用いたEB1 のCH ドメインの微小管との結合界面の特定2012
- Author(s)
  Teppei Kanaba, Ryoko Maesaki, Tomoyuki Mori, Yutaka Ito, Toshio Hakoshima, Masaki Mishima
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学東山キャンパス (愛知県名古屋市)
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 酵母の酸化ストレス耐性に関与するN-アセチルトランスフェラーゼMpr1の構造機能解析2012
- Author(s)
  那須野亮, 平野良憲, 伊藤貴文, 箱嶋敏雄, 日び隆雄, 高木博史
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡県福岡市)
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 植物ホルモン受容体構造研究の最近の進歩2012
- Author(s)
  箱嶋敏雄
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県福岡市)
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 複合体構造研究のひと工夫/Technical tips for solving problems in structural studies of protein complexes2011
- Author(s)
  箱嶋敏雄
- Organizer
  第11回日本蛋白質科学会年会ワークショップ「複合体構造研究のひと工夫」
- Place of Presentation
  大阪府吹田市
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 微小管ダイナミクスを制御する蛋白質群についての構造研究2011
- Author(s)
  金場哲平、佐伯邦道、森智行、前崎綾子、伊藤隆、箱嶋敏雄、三島正規
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  吹田
- Data Source
  KAKENHI-PROJECT-23770124
[Presentation] 微小管ダイナミクスを制御する蛋白質群についての構造研究2011
- Author(s)
  金場哲平、佐伯邦道、森智行、前崎綾子、伊藤隆、箱嶋敏雄、三島正規
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  吹田
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-23770124
[Presentation] Structural studies of tubulin tyrosine ligase 12011
- Author(s)
  Kunimichi Saeki, Ryoko Maesaki, Yutaka Ito, Toshio Hakoshima, and Masaki Mishima
- Organizer
  ISNMR2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770124
[Presentation] 複合体構造研究の一工夫2011
- Author(s)
  箱嶋敏雄, 稲垣冬彦
- Organizer
  第11回蛋白質科学会年会
- Place of Presentation
  吹田市
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-ORGANIZER-22121001
[Presentation] タンパク質を加工する/Modification of proteins for structural determination2011
- Author(s)
  箱嶋敏雄
- Organizer
  第11回日本蛋白質科学会年会ワークショップ「複合体構造研究のひと工夫」
- Place of Presentation
  大阪府吹田市
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] Structural studies of tubulin tyrosine ligase 12011
- Author(s)
  Kunimichi Saeki, Ryoko Maesaki, Yutaka Ito, Toshio Hakoshima, and Masaki Mishima
- Organizer
  ISNMR2011 Yokohama 2011
- Data Source
  KAKENHI-PROJECT-23770124
[Presentation] 植物ホルモン受容体の構造研究2010
- Author(s)
  箱嶋敏雄
- Organizer
  蛋白研セミナー
- Place of Presentation
  吹田
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] 構造生物学における第三の波2010
- Author(s)
  箱嶋敏雄
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] 植物ホルモン受容体の構造研究2010
- Author(s)
  箱嶋敏雄
- Organizer
  蛋白研セミナー
- Place of Presentation
  大阪府吹田市
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 構造生物学における第三の波2010
- Author(s)
  箱嶋敏雄
- Organizer
  第33回日本分子生物学会年会ワークショップ「構造細胞生物学の新展開」
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] CD44の細胞内相互作用の構造的基礎2010
- Author(s)
  箱嶋敏雄
- Organizer
  第74回日本生化学会中部支部例会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] 複合体研究の基礎と応用:+TIPs間の相互作用と阻害剤2009
- Author(s)
  箱嶋敏雄
- Organizer
  第9回日本蛋白質科学会年会ワークショップ「細胞内シグナル伝達の構造生物学とその応用」
- Place of Presentation
  熊本
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PUBLICLY-21025021
[Presentation] 複合体研究の基礎と応用:+TIPs間の相互作用と阻害剤2009
- Author(s)
  箱嶋敏雄
- Organizer
  第9回日本蛋白質科学会年会ワークショップ「細胞内シグナル伝達の構造生物学とその応用」
- Place of Presentation
  熊本
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] ジベレリン受容体によるジベレリン誘導性DELLA認識2009
- Author(s)
  箱嶋敏雄
- Organizer
  2009年植物科学シンポジウム「ひき出そう植物科学の潜在力:日本発GM植物実現を目指して」
- Place of Presentation
  品川
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] ジベレリン受容体によるジベレリン誘導性DELLA認識2009
- Author(s)
  箱嶋敏雄
- Organizer
  2009年植物科学シンポジウム「ひき出そう植物科学の潜在力:日本発GM植物実現を目指して」
- Place of Presentation
  品川
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PUBLICLY-21025021
[Presentation] 構造生物学の現代細胞生物学への展開2009
- Author(s)
  箱嶋敏雄
- Organizer
  特定領域研究「生体超分構造」第6回公開シンポジウム
- Place of Presentation
  豊中
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] 構造生物学の現代細胞生物学への展開2009
- Author(s)
  箱嶋敏雄
- Organizer
  特定領域研究「生体超分構造」第6回公開シンポジウム
- Place of Presentation
  豊中
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] ジベレリン受容体GID1とDELLAタンパク質複合体の構造2009
- Author(s)
  箱嶋敏雄
- Organizer
  特定領域研究「生体超分子の構造形成と機能制御の原子機構」第5回ワークショップ
- Place of Presentation
  葉山
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] ジベレリン受容体によるジベレリン誘導性DELLA認識2009
- Author(s)
  箱嶋敏雄
- Organizer
  2009年植物科学シンポジウム「ひき出そう植物科学の潜在力:日本発GM植物実現を目指して」
- Place of Presentation
  品川
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] ジベレリン受容体によるジベレリン誘導性DELLA認識2009
- Author(s)
  箱嶋敏雄
- Organizer
  2009年植物科学シンポジウム「ひき出そう植物科学の潜在力:日本発GM植物実現を目指して」
- Place of Presentation
  品川
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20011006
[Presentation] ジベレリン受容体のジベレリン識別とエフェクター認識の構造的基礎2009
- Author(s)
  箱嶋敏雄
- Organizer
  第32回日本分子生物学会年会ワークショップ「翻訳後修飾・分解による細胞制御の構造生物学の最前線」
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PUBLICLY-21025021
[Presentation] ジベレリン受容体のジベレリン識別とエフェクター認識の構造的基礎2009
- Author(s)
  箱嶋敏雄
- Organizer
  第32回日本分子生物学会年会ワークショップ「翻訳後修飾・分解による細胞制御の構造生物学の最前線」
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] Structure of a novel membrane-targeting domain found in Rac GEF Tiam1/22009
- Author(s)
  Toshio Hakoshima
- Organizer
  International Symposium on Molecular Soft Interactions in Biological Systems
- Place of Presentation
  大阪
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-19036014
[Presentation] ジベレリン受容体のジベレリン識別とエフェクター認識の構造的基礎2009
- Author(s)
  箱嶋敏雄
- Organizer
  第32回日本分子生物学会年会ワークショップ「翻訳後修飾・分解による細胞制御の構造生物学の最前線」
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] ジベレリン受容体のジベレリン識別とエフェクター認識の構造的基礎2009
- Author(s)
  箱嶋敏雄
- Organizer
  第32回日本分子生物学会年会ワークショップ「翻訳後修飾・分解による細胞制御の構造生物学の最前線」
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20011006
[Presentation] Rho-キナーゼの新規な脂質メディエータ認識の構造的基礎2009
- Author(s)
  箱嶋敏雄
- Organizer
  財団法人小野医学研究財団第20回研究成果発表会
- Place of Presentation
  豊中
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] ジベレリン受容体GIDIとDELLAタンパク質複合体の構造2009
- Author(s)
  箱嶋敏雄
- Organizer
  特定領域研究「生体超分子の構造形成と機能制御の原子機構」第5回ワークショップ
- Place of Presentation
  葉山
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] 複合体研究の基礎と応用:+TIPs間の相互作用と阻害剤2009
- Author(s)
  箱嶋敏雄
- Organizer
  第9回日本蛋白質科学会年会ワークショップ「細胞内シグナル伝達の構造生物学とその応用」
- Place of Presentation
  熊本
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20011006
[Presentation] 複合体研究の基礎と応用:+TIPs間の相互作用と阻害剤2009
- Author(s)
  箱嶋敏雄
- Organizer
  第9回日本蛋白質科学会年会ワークショップ「細胞内シグナル伝達の構造生物学とその応用」
- Place of Presentation
  熊本市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] NMR study of HAC1 mRNA recognized by endoplasmic reticulum stress sensor Ire1p(NMR を用いた小胞体ストレスセンサータンパク質Ire1pの基質認識機構の解析)2009
- Author(s)
  Ikumi Kawahara, JunGoo Jee, Rikou Tanaka, Toshiyuki Kohno, Toshio Hakoshima, Yusuke Imagawa, Kenji Kohno, Yoshiyuki Tanaka, Chojiro Kojima
- Organizer
  The 32nd Annual Meeting of the Molecular Biology Society of Japan(日本分子生物学会年会)
- Place of Presentation
  Pacifico Yokohama, Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-20370038
[Presentation] RacGEF Tiam1/2の新規なタンパク質標的認識ドメインの構造2008
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)シンポジウム「シグナル伝達タンパク質の分子認識研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20011006
[Presentation] RacGEF Tiam1/2の新規なタンパク質標的認識ドメインの構造2008
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)シンポジウム「シグナル伝達タンパク質の分子認識研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] RacGEF Tiam1/2の新規なタンパク質標的認識ドメインの構造2008
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)シンポジウム「シグナル伝達タンパク質の分子認識研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19036014
[Presentation] 酵母Ire1pによって部位特異的な切断を受けるRNAのNMR構造解析2008
- Author(s)
  河原郁美、Jee JunGoo、箱嶋敏雄、今川佑介、河野憲二、児嶋長次郎
- Organizer
  第47回NMR討論会
- Place of Presentation
  筑波大学大学会館講堂、つくば
- Data Source
  KAKENHI-PROJECT-20370038
[Presentation] Rho-キナーゼの構造と活性制御: 非典型AGCキナーゼとしての特徴2008
- Author(s)
  箱嶋敏雄
- Organizer
  第283回CBI研究講演会「キナーゼの構造多様性と阻害剤の開発」
- Place of Presentation
  東京
- Year and Date
  2008-02-21
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] Rho-キナーゼの構造と活性制御:非典型AGCキナーゼとしての特徴2008
- Author(s)
  箱嶋敏雄
- Organizer
  第283回CBI研究講演会「キナーゼの構造多様性と阻害剤の開発」
- Place of Presentation
  東京
- Year and Date
  2008-02-21
- Data Source
  KAKENHI-PROJECT-19036014
[Presentation] RacGEF Tiam1/2の新規なタンパク質標的認識ドメインの構造2008
- Author(s)
  箱嶋敏雄
- Organizer
  BB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)シンポジウム「シグナル伝達タンパク質の分子認識研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19037017
[Presentation] RacGEF Tiam1/2の新規なタンパク質標的認識ドメインの構造2008
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)シンポジウム「シグナル伝達タンパク質の分子認識研究の新展開」
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20051017
[Presentation] Structural basis for neutral endopeptidas 24.11 recognition by ERM proteins2008
- Author(s)
  Toshio Hakoshima
- Organizer
  特定領域研究「膜インタフェイス」国際シンポジウムin福岡
- Place of Presentation
  福岡
- Year and Date
  2008-01-25
- Data Source
  KAKENHI-PROJECT-19036014
[Presentation] ERMタンパク質によるペプチド認識: 特異性と複数結合部位の干渉性2007
- Author(s)
  箱嶋敏雄
- Organizer
  日本生物物理学会第45回(2007年度)年会シンポジウム「タンパク質リガンド相互作用」
- Place of Presentation
  横浜
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] ERMタンパク質によるペプチド認識:特異性と複数結合部位の干渉性2007
- Author(s)
  箱嶋敏雄
- Organizer
  日本生物物理学会第45回(2007年度)年会シンポジウム「タンパク質リガンド相互作用」
- Place of Presentation
  横浜
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-19036014
[Presentation] CLIP-170による微小管認識の構造的基礎2007
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)ワークショップ「細胞極性を決定・制御・活用するタンパク質の機能構造研究」
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19207010
[Presentation] CLIP-170による微小管認識の構造的基礎2007
- Author(s)
  箱嶋敏雄
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)ワークショップ「細胞極性を決定・制御・活用するタンパク質の機能構造研究」
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19037017
[Presentation] 創薬を指向したタンパク質結晶学
- Author(s)
  箱嶋　敏雄
- Organizer
  日本薬学会第134年会一般シンポジウムS38 薬学における結晶学とその応用―2014 世界結晶年を記念して―
- Place of Presentation
  パレア(熊本県熊本市)
- Year and Date
  2014-03-27 – 2014-03-30
- Invited
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] タンパク質を加工する/ Modification of proteins for structural determination
- Author(s)
  箱嶋　敏雄
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪府　吹田市
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] RM蛋白質による膜貫通型プロテアーゼMT1-MMP認識の構造的基盤
- Author(s)
  寺脇慎一，北野健，青山美樹，箱嶋敏雄
- Organizer
  平成24年度　日本生化学会　関東支部例会
- Place of Presentation
  群馬大学　昭和キャンパス（群馬県前橋市）
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 構造細胞生物学への展開「何がわかって、何がわかっていないのか」
- Author(s)
  箱嶋　敏雄
- Organizer
  2012年度若手ワークショップ
- Place of Presentation
  ホテルあかね (神奈川県足柄下郡湯河原町)
- Invited
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 膜貫通型プロテアーゼMT1-MMP のERM 蛋白質による細胞骨格連結の構造的基盤
- Author(s)
  寺脇慎一, 北野健, 青山美樹, 箱嶋敏雄
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館(鳥取県鳥取市)
- Year and Date
  2013-06-12 – 2013-06-14
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] 酵母の酸化ストレス耐性に関与するN-アセチルトランスフェラーゼMpr1の構造機能解析
- Author(s)
  那須野亮, 平野良憲, 伊藤貴文, 箱嶋敏雄, 日び隆雄, 高木博史
- Organizer
  食品酵素化学研究会第１３回学術講演会
- Place of Presentation
  大阪府立大学 I-siteなんば(大阪府大阪市)
- Year and Date
  2013-09-19 – 2013-09-20
- Data Source
  KAKENHI-PLANNED-22121002
[Presentation] PCNAのリングの内側に存在する酸性アミノ酸残基の機能解析/ Molecular analysis of acidic amino acid residues in the center hole of PCNA
- Author(s)
  箱嶋　敏雄
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪府　吹田市
- Data Source
  KAKENHI-PLANNED-22121002

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HAKOSHIMA Toshio 箱嶋 敏雄

箱嶋 敏雄 ハコシマ トシオ

HAKOSHIMA. Toshio 箱嶋 敏雄

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Co-Researchers

Design of a new mechano-sensorPrincipal Investigator

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Structural and physical properties of the clutch molecular complex in motile cells.Principal Investigator

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Structural studies on tubulin tyrosine ligase and its application.

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Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.Principal Investigator

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Structural biology of animal and plant signaling proteinsPrincipal Investigator

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Structural basis of cell-signalling complexes mediating signal perception, transduction and responsesArea Organizer

Area Organizer

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ユビキチン化シャペロンの基礎研究Principal Investigator

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癌細胞の浸潤・転移関連RacGEFと細胞接着分子の構造生物学Principal Investigator

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細胞膜足場形成の多次元複合体の構造生物学Principal Investigator

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Structural bases of spliceosome indepemdent splicing

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膜貫通型プロテアーゼの細胞骨格への連結の構造的基礎Principal Investigator

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微小管ダイナミックス制御の構造的基礎Principal Investigator

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Structural biology of cytoskeletal control by dynamic protein complex formation.Principal Investigator

Principal Investigator

Project Period (FY)

HAKOSHIMA Toshio 箱嶋敏雄

箱嶋敏雄ハコシマトシオ

HAKOSHIMA. Toshio 箱嶋敏雄