HINODA Yuji 日野田裕治

… Alternative Names

日野田裕冶ヒノダユウジ

日野田祐治ヒノダユウジ

日野田裕二ヒノダユウジ

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Researcher Number	10165128
External Links
Affiliation (based on the past Project Information) *help	2012: 山口大学, 医学(系)研究科(研究院), 教授 2006 – 2011: 山口大学, 大学院・医学系研究科, 教授 1999 – 2005: 山口大学, 医学部, 教授 1994 – 1998: 札幌医科大学, 医学部, 助教授 1997: 札幌医科大学, 助教授 … More 1995: 札幌医科大学, 1内, 助教授 1994: 札幌医大, 1内, 講師 1992 – 1994: Sapporo Medical College, Dept. of Int. Med., Assist. Prof., 医学部, 講師 1993: 札幌医科大学, 第1内科, 講師 1986 – 1991: Sapporo Medical College, Department of Medicine, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Laboratory medicine / Biological Sciences / 内科学一般 Except Principal Investigator Gastroenterology / 内科学一般 / Digestive surgery / 化学工学一般 / Laboratory medicine / Functional biochemistry
Keywords	Principal Investigator 大腸癌 / mRNA / モノクローナル抗体 / MAdCAM-1 / c-kit / Renal cell carcinoma / Frizzled-7 / Wntシグナル経路 / MUC1 / 樹状細胞 … More / RHAMM / 免疫遺伝子療法 / アンチセンス抑制 / gene therapy / inflammatory bowel diseases / TNBS-induced colitis / antisense oligonucleotides / 炎症性腸疾患、 / TNBS腸炎、 / アンチセンス抑制、 / MAdCAM-1、 / 遺伝子療法 / 炎症性腸疾患 / TNBS腸炎 / T cell receptor gamma chain / Single chain antibody / HLA-unrestricted / cytotoxic T cells / レトロウイルスベクター / MUC1ムチン / レトロウィルスベクター / cytotoxic T細胞 / T細胞受容体γ鎖 / 単鎖抗体 / alternative promotor / colorectal cancer / Alternative Promoter / alternative promoter / 抗イディオタイプ抗体 / 腺癌関連抗原 / Tumor suppressor gene / Bladder cancer / miR-493 / miR-1826 / miRNA / FFPE / DNAメチル化 / 腎細胞癌 / DKK4 / DKK3 / KRAS / Wnt11 / Colorectal cancer / 抗体療法 / Interferon-γ / 結核菌抗原 / 免疫学的モニタリング / siRNA / 大腸癌細胞 / rizzled-7 / 細胞プロセシング / 樹状細胞療法 / si-RNA / frizzled-7 / 細胞表面抗原分子 / 免疫療法 / がん / GalNAc transferase / O-glycan / 膵癌 / リポソーム / CTL / ペプチドワクチン / ELISPOT / EL4 / EGFP / B16 / TRP2 / cancer immunotherapy / MHC class II / dendritic cells / O-グリカン / GalNAcトランスフェラーゼ / BGPI mRNA / CEA / 肝 / 胆汁 / BGPI / 肝細胞癌 / CEAファミリー / Biliary glycoprotein / 抗合成ペプチドモノクローナル抗体 / transfectoma / in situ hybridization / Nonspecific crossreacting antigen / Biliary glycoprotein I … More Except Principal Investigator モノクローナル抗体 / チロシンホスファターゼ / セリン / プロテインホスファターゼ / モノクロ-ナル抗体 / SHP-2 / アンチセンスDNA・RNA / 画像診断 / 養子免疫療法 / バイスペシフィック抗体 / イディオタイプネットワーク / 主要組織適合抗原複合体結合ペプチド / 膵癌 / ICAM-1 / 癌形質 / 発癌 / スレオニンホスファターゼ / 自己抗体 / DNA / SNPs / gastric pre-cancerous lesions / mucin genes / 胃前癌病変 / ムチン遺伝子 / SHPS-1 / Immuno-PCR / Monoclonal antibody / Campylobacter pylori / 慢性胃炎 / ヘリコバクタ・ピロリ菌 / 遺伝子発現 / 細胞増殖 / エピトープ / CTL / MUC1 / ムチン抗原 / CEA / autoimmune disease / anti-idiotypic antibody / 抗イディオタイプ抗体 / Human monoclonal antibody / Autoantigen / Autoantibody / ヒト型モノクローナル抗体 / 自己抗原 / Chemotherapy / Immunotherapy / Pancreatic cancer / 化学療法 / 免疫療法 / size exclusion curve / electrostatic interaction / conformational changes / melt curve / biorecognition / chromatography / イオン交換クロマトグラフィー / DNA二重鎖形成反応 / 生体認識 / サイズ排除特性 / 静電気的相互作用 / クロマトグラフィー / blood culture / database / quality assurance / quick diagnosis / infectious disease / Gram's stein / visualized data transfer / Quality Assurance / 血液培養 / データベース / 品質管理 / 迅速診断 / 感染症 / グラム染色 / 画像伝送 / methylation / DNA repair genes / genomic instability / メチレ-ション / メチレーション / DNA修復遺伝子 / 遺伝子不安定性 / Barett esohagus / gastric cancer / Intestinal metaplasia / 分子機構解析 / バレット食道 / 腸型胃癌 / 腸上皮化生 / B cell antigen receptor / Tautomycin / Tyrosine protein phosphatase / threonine protein phosphatase / Serine / Protein phosphatase / Signal transduction / オカダ酸 / アルツハイマー病 / 長期増強 / CD45 / ノジュラリン / B細胞抗原受容体 / トウトマイシン / トレオニンホスファターゼ / 細胞内情報伝達 / Antigen MUSE 11 / Pancreas cancer / MUSE11抗原 / sIgA / Gastric juice / Analysis of the Disease / Chronic gastritis / H. pylori / SIgA抗体 / SIgA / 胃液 / 病態解析 / ヘリコバタタ・ピロリ菌 / beta-protein / Alzheimer's disease / Amyloid associated protein / Amyloidosis / β-蛋白 / 続発性アミロイド-シス / アミロイド / アミロイド関連蛋白 / β蛋白 / アルツハイマ-病 / アモロイド関連蛋白 / アミロイド-シス / Local immune response / Monoclinal antibody / Chronic Gastritis / Helicobacter pylori / 組織学的重症度 / 十二指腸潰瘍 / 胃潰瘍 / 局所免疫応答 / カンピロバクタ・ピロリ菌 / DNAプローブ / 癌遺伝子 / 前癌病変マーカー / 新しい治療法 / 癌細胞増殖抑制 / Anoikis / Apoptosis / Metastasis / BAG-1 / PKC / 遺伝子解析 / DNA解析 / RDA法 / 新遺伝子 / 家族集積性胃癌 / 0-グリコシド結合型糖鎖 / HLA非拘束性 / cytotoxic T 細胞 / MUC1ムチン / 細胞傷害性T細胞 / レチノイン酸 / 治療 / 浸潤 / マトリライシン / 大腸癌 / 分子腫瘍学 / MUC-1 / 腫瘍関連ムチン / 脱糖鎖 / 抗ムチン抗体 / 細胞障害生T細胞 / 蛋白脱リン酸 / 細胞障害性T細胞 / 蛋白脱リン後 / RT-PCR法 / ムチン抗原遺伝子 / 腫瘍細胞 / MUSE11 / PCR / 早期診断 / 膵炎 / タンデム・リピート / MuC-1遺伝子 / 糖鎖異常 / 抗ムチン抗原 / チロシン脱リン酸化酵素 / CEAファミリー / DCC / セレクチンファミリー / 細胞間接着分子 / 細胞周期 / イソホーム / 再生肝 / エピト-プ解析 / MUCー1遺伝子 / ムチン分子 / BGP / トランスジェニックマウス / 消化器癌マ-カ- / ムチン・コア蛋白 / 癌診断 / 遺伝子クロ-ニング / ムチン関連癌抗原 / トランスフェクト-マ / CEAファミリ-遺伝子 / BGPI / NCA Less

大腸癌新規マイクロRNAマーカーの開発Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Yamaguchi University
癌の診断・予後判定に有用な遺伝子マーカーの前向き研究による開発と臨床検査への応用Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Yamaguchi University
Cell surface antigenic molecules as targets for immunotherapyPrincipal Investigator
- Principal Investigator
  
  HINODA Yuji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Development of high performance chromatography-based gene detection system
- Principal Investigator
  
  YAMAMOTO Shuichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  化学工学一般
- Research Institution
  Yamaguchi University
Combination therapy with immunotherapy and chemotherapy for pancreatic cancer
- Principal Investigator
  
  YAMAMOTO Koutaro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
ムチン分子を標的とした上皮性腫瘍の免疫遺伝子療法Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Analysis of molecular mechanism of premalignant lesion of the stomach using genomic instability and new mucin gene.
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
A multiple aimed, dual directional, and visualized data transfer system for bacterial infection control. - A quick microscopic diagnosis system. -
- Principal Investigator
  
  DAIKAI Sadamitsu, MATSUNO Youko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Yamaguchi University
Development of a new therapeutic modality with antisense suppression of MAdCAM-1 gene expression for inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  HINODA Yuji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University School of Medicine
チロシンホスファターゼSHP2の制御に基づく免疫強化療法の開発
- Principal Investigator
  
  安達正晃
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Sapporo Medical University
家族集積性胃癌関連遺伝子のRDA法による同定
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
AnalysIs of molecular mechanism of gastric pre-cancerous lesions by using new mucin genes
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
GalNAc:ポリペプチド・トランスフェラーゼの発現抑制による癌治療法の開発Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Physiological significance of protein phosphatases on cellular signal transduction
- Principal Investigator
  
  TAKEDA Masao
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIROSHIMA UNIVERSITY
Preparation of HLA-unrestricted anti-tumor cytotoxic T cells by gene transfer.Principal Investigator
- Principal Investigator
  
  HINODA Yuji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical University
抗原分子を基盤とした癌免疫療法の基礎的研究
- Principal Investigator
  
  高橋利忠
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Aichi Cancer Center Research Institute
MUC1ムチンを標的とした新しい腫瘍免疫療法の開発
- Principal Investigator
  
  仲川尚明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Development of a supersensitive detection method for pancreas cancer associated antigen and tumor suppressor gene by using immuno-PCR.
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University, School of Medicine
発癌過程ならびに癌細胞形質の発現におけるプロテインホスファターゼの意義
- Principal Investigator
  
  菊地九二三
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
抗原分子を基盤とした癌免疫療法の基礎的研究
- Principal Investigator
  
  高橋利忠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Aichi Cancer Center Research Institute
腫瘍関連ムチンのがん診断治療への応用
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
マトリライシン(MMP-7)の発現抑制による大腸癌浸潤抑制の基礎的検討
- Principal Investigator
  
  伊東文生
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Analyzes of expression and function of aberrant c-kit transcript in gastrointestinal cancers.Principal Investigator
- Principal Investigator
  
  HINIDA Yuji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
発癌過程ならびに癌細胞形質の発現におけるプロテインホスファターゼの意義
- Principal Investigator
  
  菊池九二三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
抗原分子を基盤とした癌免疫療法の基礎的研究
- Principal Investigator
  
  高橋利忠
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
発癌過程ならびに癌細胞形質の発現におけるプロテインホスファターゼの意義
- Principal Investigator
  
  KIKUCHI Kunimi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
新しい癌関連ムチンコア蛋白抗原の遺伝子およびエピトープ解析と診断応用
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
新しい接着分子としてのBGPIの臨床的意義と機能解析Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical University
消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
新しいムチン関連癌抗原コア蛋白の遺伝子クロ-ニングと臨床応用への基礎
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Association of H. pylori with immunological aspects of chronic gastritis
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical College
CEA遺伝子ファミリ-の機能ならびに発現調節機構の解析
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
新しいムチン関連癌抗原コア蛋白の遺伝子クロ-ニングと臨床応用への基礎
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
CEA関連抗原遺伝子の分子生物学的解析および産物の機能Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical College
Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene Analysis
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎Principal Investigator
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Patent

[Journal Article] TWIST1 hyper- methylation is observed frequently in colorectal tumors and its overexpression is associated with2009
- Author(s)
  Okada T, Suehiro Y, Ueno K, Mitomori S, Kaneko S, Nishioka M, Okayama N, Sakai K, Higaki S, Hazama S, Hirata H, Sakaida I, Oka M, Hinoda Y
- Journal Title
  
  Genes Chromosomes Cancer 49
  
  Pages: 452-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma2009
- Author(s)
  Kawai Y, Sakano S, Suehiro Y, Okada T, Korenaga Y, Hara T, Naito K, Matsuyama H, Hinoda Y
- Journal Title
  
  Ann Oncol (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Vaccine therapy with dendritic cells transfected with Il13ra2 mRNA for glioma in mice2009
- Author(s)
  Saka M, Amano T, Kajiwara K, Yoshikawa K, Ideguchi M, Nomura S, Fujisawa H, Kato S, Fujii M, Ueno K, Hinoda Y, Suzuki M
- Journal Title
  
  J Neurosurg (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] The bcl2 -938CC genotype has poor prognosis and lower survival in renal cancer2009
- Author(s)
  Hirata H, Hinoda Y, Nakajima K, Kikuno N, Suehiro Y, Tabatabai ZL, Ishii N, Dahiya R
- Journal Title
  
  J Urol 182
  
  Pages: 721-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism2009
- Author(s)
  Hazama S, Nagashima A, Kondo H, Yoshida S, Shimizu R, Araki A, Yoshino S, Okayama N, Hinoda Y, Oka M
- Journal Title
  
  Cancer Sci 101
  
  Pages: 722-7
- NAID
  10026589707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells2009
- Author(s)
  Ueno K, Hazama S, Mitomori S, Nishioka M, Suehiro Y, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y
- Journal Title
  
  Br J Cancer 101
  
  Pages: 1374-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Association of TP53 and MDM2 polymorphisms with survival in bladder cancer patients treated with chemoradiotherapy2009
- Author(s)
  Shinohara A, Sakano S, Hinoda Y, Nishijima J, Kawai Y, Misumi T, Nagao K, Hara T, Matsuyama H
- Journal Title
  
  Cancer Sci 100
  
  Pages: 2376-82
- NAID
  10027198427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Bcl2 -938C/A polymorphism carries increased risk of biochemical recurrence after radical prostatectomy2009
- Author(s)
  Hirata H, Hinoda Y, Kikuno N, Suehiro Y, Shahryari V, Ahmad AE, Tabatabai ZL, Igawa M, Dahiya R
- Journal Title
  
  J Urol 181
  
  Pages: 1907-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Role of secreted frizzled-related protein 3 in human renal cell carcinoma2009
- Author(s)
  Hirata H, Hinoda Y, Ueno K, Majid S, Saini S, Dahiya R
- Journal Title
  
  Cancer Res 70
  
  Pages: 1896-905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways2009
- Author(s)
  Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Kawakami K, Yamamura S, Ueno K, Majid S, Saini S, Ishii N, Dahiya R
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 5678-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Wnt antagonist gene polymorphisms and renal cancer2009
- Author(s)
  Hirata H, Hinoda Y, Nakajima K, Kikuno N, Yamamura S, Kawakami K, Suehiro Y, Tabatabai ZL, Ishii N, Dahiya R
- Journal Title
  
  Cancer 115
  
  Pages: 4488-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] changes in aberrant crypt foci and serrated polyps2008
- Author(s)
  Suehiro Y, Hinoda Y. Genetic, epigenetic
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1071-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] polymorphisms are risk factors for endometrial cancer susceptibility2008
- Author(s)
  Hirata H, Hinoda Y, Okayama N, Suehiro Y, Kawamoto K, Kikuno N, Rabban JT, Chen LM, Dahiya R. CYP1A1, SULT1A1, SULT1E1
- Journal Title
  
  Cancer 112
  
  Pages: 1964-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] COMT polymorphisms affecting protein expression are risk factors for endometrial cancer2008
- Author(s)
  Hirata H, Hinoda Y, Okayama N, Suehiro Y, Kawamoto K, Kikuno N, Rabban JT, Chen LM, Dahiya R
- Journal Title
  
  Mol Carcinog 47
  
  Pages: 768-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Frizzled-7 as a potential therapeutic target in colorectal cancer2008
- Author(s)
  Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y
- Journal Title
  
  Neoplasia 10
  
  Pages: 697-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Mismatch repair gene MSH3 polymorphism is associated with the risk of sporadic prostate cancer2008
- Author(s)
  Hirata H, Hinoda Y, Kawamoto K, Kikuno N, Suehiro Y, Okayama N, Tanaka Y, Dahiya R
- Journal Title
  
  J Urol 179
  
  Pages: 2020-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] DNA repair gene polymorphisms may be associated with prognosis of upper urinary tract transitional cell carcinoma2008
- Author(s)
  Sasaki M, Sakano S, Okayama N, Akao J, Hara T, Kawai Y, Ohmi C, Hinoda Y, Naito K
- Journal Title
  
  Neoplasia 10
  
  Pages: 255-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes2008
- Author(s)
  Kondo H, Hazama S, Kawaoka T, Yoshino S, Yoshida S, Tokuno K, Takashima M, Ueno T, Hinoda Y, Oka M
- Journal Title
  
  Anticancer Res 28
  
  Pages: 379-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Epigenetic-Genetic Interactions in the APC/WNT, RAS/RAF, and P53 Pathways in Colorectal Carcinoma2008
- Author(s)
  Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, Morris J, Issa JP, Yuen ST, Leung SY, Hamilton SR
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 2560-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Aneuploidy predicts outcome in patients with endometrial carcinoma and is related to lack of CDH13 hypermethylation2008
- Author(s)
  Suehiro Y, Okada T, Okada T, Anno K, Okayama N, Ueno K, Hiura M, Nakamura M, Kondo T, Oga A, Kawauchi S, Hirabayashi K, Numa F, Ito T, Saito T, Sasaki K, Hinoda Y
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 3354-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Hyper- methylation status of APC inversely correlates with the presence of submucosal invasion in laterally spreading colorectal tumors2008
- Author(s)
  Hashimoto K, Shimizu Y, Suehiro Y, Okayama N, Hashimoto S, Okada T, Hiura M, Ueno K, Hazama S, Higaki S, Hamanaka Y, Oka M, Sakaida I, Hinoda Y
- Journal Title
  
  Mol Carcinog 47
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] A simple immunomonitoring procedure for mRNAloaded dendritic cell therapy2007
- Author(s)
  Hiura M, Ueno K, Suehiro Y, Hazama S, Oka M, Imai K, Hinoda Y
- Journal Title
  
  Tumour Biol 28
  
  Pages: 350-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Association of interleukin-19 gene polymorphisms with age2007
- Author(s)
  Okayama N, Suehiro Y, Hamanaka Y, Nakamura J, Hinoda Y
- Journal Title
  
  J Gerontol A Biol Sci Med Sci 62
  
  Pages: 507-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma2007
- Author(s)
  Hirata H, Hinoda Y, Kikuno N, Kawamoto K, Suehiro Y, Tanaka Y, Dahiya R
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 4123-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility2007
- Author(s)
  Hirata H, Hinoda Y, Kikuno N, Kawamoto K, Dahiya AV, Suehiro Y, Tanaka Y, Dahiya R
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 5056-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] The association of DNA repair gene polymorphisms with the development and progression of renal cell carcinoma2007
- Author(s)
  Sakano S, Hinoda Y, Okayama N, Kawai Y, Korenaga Y, Eguchi S, Nagao K, Ohmi C, Naito K
- Journal Title
  
  Ann Oncol 18
  
  Pages: 1817-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Antitumor effects of vaccination with dendritic cells transfected with modified receptor for hyaluronan-mediated motility mRNA in a mouse glioma model2007
- Author(s)
  Amano T, Kajiwara K, Yoshikawa K, Morioka J, Nomura S, Fujisawa H, Kato S, Fujii M, Fukui M, Hinoda Y, Suzuki M
- Journal Title
  
  J Neurosurg 106
  
  Pages: 638-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Polymorphisms of DNA repair genes are risk factors for prostate cancer2007
- Author(s)
  Hirata H, Hinoda Y, Tanaka Y, Okayama N, Suehiro Y, Kawamoto K, Kikuno N, Majid S, Vejdani K, Dahiya R
- Journal Title
  
  Eur J Cancer 43
  
  Pages: 231-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Antisense Therapy of MAdCAM-1 for Trinitrobenzenesulfonic Acid-Induced Murine Colitis2006
- Author(s)
  Goto A, Arimura Y, Shinomura Y, Imai K, Hinoda Y
- Journal Title
  
  Inflamm. Bowel Dis 12
  
  Pages: 758-765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and neck squamous cell carcinoma2006
- Author(s)
  Hashimoto T, Uchida K, Okayama N, Imate Y, Suehiro Y, Hamanaka Y, Ueyama Y, Yamashita H, Hinoda Y
- Journal Title
  
  Mol Carcinog 45
  
  Pages: 344-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Polymorphisms of DNA repair genes are associated with renal cell carcinoma. Biochem2006
- Author(s)
  Hirata H, Hinoda Y, Matsuyama H, Tanaka Y, Okayama N, Suehiro Y, Zhao H, Urakami S, Kawamoto K, Kawakami T, Igawa M, Naito K, Dahiya R
- Journal Title
  
  Biophys. Res. Commun 342
  
  Pages: 1058-1062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Anti-tumor activity of dendritic cells transfected with mRNA for receptor for hyaluronan-mediated motility is mediated by CD4+ T cells2006
- Author(s)
  Fukui M, Ueno K, Suehiro Y, Hamanaka Y, Imai K, Hinoda Y
- Journal Title
  
  Cancer Immunol Immunother 55
  
  Pages: 538-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Relation between cytokine promoter gene polymorphism and toxicity of 5-fluorouracil plus cisplatin chemotherapy2006
- Author(s)
  Sakamoto K, Oka M, Yoshino S, Hazama S, Abe T, Okayama N, Hinoda Y
- Journal Title
  
  Oncol Rep 16
  
  Pages: 381-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Catechol-O- methyltransferase gene polymorphisms in benign prostatic hyperplasia and sporadic prostate cancer2006
- Author(s)
  Tanaka Y, Sasaki M, Shiina H, Tokizane T, Deguchi M, Hirata H, Hinoda Y, Okayama N, Suehiro Y, Urakami S, Kawakami T, Kaneuchi M, Pookot D, Igawa M, Okuyama A, Ishii N, Dahiya R
- Journal Title
  
  Cancer Epidemiol. Biomarkers Prev 15
  
  Pages: 238-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours2005
- Author(s)
  Murai M, Toyota M, Satoh A, Suzuki H, Akino K, Mita H, Sasaki Y, Ishida T, Shen L, Garcia-Manero G, Issa JP, Hinoda Y, Tokino T, Imai K
- Journal Title
  
  Br. J. Cancer 92
  
  Pages: 1165-1172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer2005
- Author(s)
  Murai M, Toyota M, Suzuki H, Satoh A, Sasaki Y, Akino K, Ueno M, Takahashi F, Kusano M, Mita H, Yanagihara K, Endo T, Hinoda Y, Tokino T, Imai K
- Journal Title
  
  Clin. Cancer Res 11
  
  Pages: 1021-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer2005
- Author(s)
  Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T
- Journal Title
  
  Gastroenterology 129
  
  Pages: 156-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis2005
- Author(s)
  Nosho K, Yamamoto H, Adachi Y, Endo T, Hinoda Y, Imai K
- Journal Title
  
  Br. J. Cancer 92
  
  Pages: 1193-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Association of the BCRP C421A polymorphism with nonpapillary renal cell carcinoma2005
- Author(s)
  Korenaga Y, Naito K, Okayama N, Hirata H, Suehiro Y, Hamanaka Y, Matsuyama H, Hinoda Y
- Journal Title
  
  Int. J. Cancer 117
  
  Pages: 431-434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis2005
- Author(s)
  Nosho K, Yoshida M, Yamamoto H, Taniguchi H, Adachi Y, Mikami M, Hinoda Y, Imai K
- Journal Title
  
  Carcinogenesis 26
  
  Pages: 892-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] MUC1 peptide vaccination in patients with advanced pancreas or biliary tract cancer2005
- Author(s)
  Yamamoto K, Ueno T, Kawaoka T, Hazama S, Fukui M, Suehiro Y, Hamanaka Y, Ikematsu Y, Imai K, Oka M, Hinoda Y
- Journal Title
  
  Anticancer Res 25
  
  Pages: 3575-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts2005
- Author(s)
  Min Y, Adachi Y, Yamamoto H, Imsumran A, Arimura Y, Endo T, Hinoda Y, Lee CT, Nadaf S, Carbone DP, Imai K
- Journal Title
  
  Gut 54
  
  Pages: 591-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016049
[Journal Article] The current status and issues concerning monoclonal antibody therapy.2004
- Author(s)
  Hinoda Y.
- Journal Title
  
  Bull.Yamaguchi Med.School 51
  
  Pages: 41-50
- NAID
  120000863927
- Data Source
  KAKENHI-PROJECT-12217097
[Journal Article] Monoclonal antibodies as effective therapeutic agents for solid tumors.2004
- Author(s)
  Hinoda Y. et al.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 621-625
- NAID
  80016809427
- Data Source
  KAKENHI-PROJECT-12217097
[Patent] 大腸腫瘍の検出方法2009
- Inventor(s)
  日野田裕治, 他
- Industrial Property Rights Holder
  日野田裕治, 他
- Filing Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-17016049
[Patent] Frizzled-7活性抑制物質2009
- Inventor(s)
  日野田裕治, 他4名
- Industrial Property Rights Holder
  山口大学
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-17016049
[Patent] Frizzled-7活性抑制物質2009
- Inventor(s)
  日野田裕治, 他
- Industrial Property Rights Holder
  日野田裕治, 他
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-17016049
[Patent] 大腸腫瘍の検出方法2009
- Inventor(s)
  日野田裕治, 他
- Industrial Property Rights Holder
  日野田裕治, 他
- Filing Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] IL13Rα2(interleukin thirteen receptor alpha2)mRNA導入樹状細胞を用いたグリオーマワクチン療法2009
- Author(s)
  坂真人、梶原浩司、天野貴之、吉川功一、出口誠、上野耕司、日野田裕治、鈴木倫保
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] RASSF1A遺伝子プロモーター領域のメチル化レベルは淡明細胞型腎癌患者の独立予後予測因子となる2009
- Author(s)
  川井禎久、坂野滋、末広寛、岡田季之、原智彦、長尾一公、原貴彦、松山豪泰、日野田裕治
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] Frizzled-7 as a Potential Therapeutic Target in Colorectal Cancer2008
- Author(s)
  Koji Ueno, Sayaka kaneko, Mikiko Nakamura, Yutaka Suehiro, Kohzoh Imai, Yuji Hinoda
- Organizer
  The 36th Meeting of the International Society of Oncologyand BioMarkers
- Place of Presentation
  ISOBM 2008, Tokyo
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] Aneuploidy Predicts Outcome in Patients with Endometrial Carcinoma and is Related to Lack of CDH13 Hypermethylation2008
- Author(s)
  Yutaka Suehiro, Yuji Hinoda
- Organizer
  The 36th Meeting of the International Society of Oncology and BioMarkers
- Place of Presentation
  ISOBM 2008, Tokyo
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] Hypermethylation status of APC predicts the presence of submucosal invasion in laterally spreading colorectal tumors2007
- Author(s)
  Yutaka Suehiro, Yuji Hinoda
- Organizer
  American Association for Cancer Research Annual Meeting
- Place of Presentation
  Los Angeles
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] A simple method for immuno-monitoring mRNA-loaded dendritic cell therapy2007
- Author(s)
  Mikako Hiura, Koji Ueno, Mikiko Fukui, Yutaka Suehiro, Kohzoh Imai, Yuji Hinoda
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-17016049
[Presentation] Frizzled-7 is a candidate therapeutic target for colorectal cancer2007
- Author(s)
  Koji Ueno, Mikako Hiura, Mikiko Fukui, Yutaka Suehiro, Kohzoh Imai, Yuji Hinoda
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-17016049

1. IMAI Kohzoh (60117603)

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51. 神奈木玲児

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 垣内英樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HINODA Yuji 日野田 裕治

日野田 裕冶 ヒノダ ユウジ

日野田 祐治 ヒノダ ユウジ

日野田 裕二 ヒノダ ユウジ

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大腸癌新規マイクロRNAマーカーの開発Principal Investigator

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癌の診断・予後判定に有用な遺伝子マーカーの前向き研究による開発と臨床検査への応用Principal Investigator

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Cell surface antigenic molecules as targets for immunotherapyPrincipal Investigator

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ムチン分子を標的とした上皮性腫瘍の免疫遺伝子療法Principal Investigator

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Development of a new therapeutic modality with antisense suppression of MAdCAM-1 gene expression for inflammatory bowel diseasesPrincipal Investigator

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GalNAc:ポリペプチド・トランスフェラーゼの発現抑制による癌治療法の開発Principal Investigator

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HINODA Yuji 日野田裕治

日野田裕冶ヒノダユウジ

日野田祐治ヒノダユウジ

日野田裕二ヒノダユウジ