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Shirahane Kengo  白羽根 健吾

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… Alternative Names

白羽根 健吾  シラハネ ケンゴ

SHIRAHANE Kengo  白羽根 健吾

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Researcher Number 10529803
Affiliation (Current) 2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help 2025: 九州大学, 医学研究院, 共同研究員
2020 – 2023: 九州大学, 医学研究院, 共同研究員
2016 – 2018: 九州大学, 医学研究院, 共同研究員
2012 – 2015: 九州大学, 医学(系)研究科(研究院), 共同研究員
2012 – 2014: 九州大学, 医学研究院, 共同研究員 … More
2013: 九州大学, 大学院医学研究院, 共同研究員
2012: 九州大学, 医学(系)研究科(研究院), 研究員
2009 – 2011: Kyushu University, 大学病院, 助教 Less
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Digestive surgery
Except Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related / Gastroenterology / General surgery
Keywords
Principal Investigator
膵癌 / 乳癌 / organoid / phenotype / 癌関連線維芽細胞 / 腫瘍微小環境 / 癌関連線維芽細胞 (CAF) / 不均一性 / オルガノイド (organoid) / 腫瘍免疫微小環境 … More / カルパイン / drug delivery system / 治療抵抗性 / 化合物ライブラリー / オートファジー / desmoplasia / 間様系幹細胞 / 間葉系幹細胞 / 癌間質相互作用 / 間質増生(desmoplasia) / 間葉系幹細胞(MSC) / 間質細胞 / 乳腺外科学 … More
Except Principal Investigator
膵癌 / 膵星細胞 / 人工ウイルス / 早期診断 / オートファジー / 膵臓癌 / 癌 / 癌間質相互作用 / CD51 / 遺伝子発現地図 / 腫瘍微小環境 / シングルセル解析 / 空間的トランスクリプトーム / Visium / 食道癌 / オートファジー抑制剤 / 創薬 / 膵前癌病変 / 膵液 / miRNA / エクソゾーム / バイオマーカー / biomarker / micro RNA / exosome / ADM / PDAC / podocalyxin / MiR-5100 / PDX / オルガノイド / podcalyxin / Mir-5100 / CD110 / podcalyxin (PODXL) / miR-5100 / microRNA / Pancreatic cancer / 遺伝子改変マウス / 治療抵抗性 / リモデリング / 癌微小環境 / DDS / MRI / ナノカプセル / perivascular cell / 間葉系幹細胞 / desmoplasia / 上皮間葉転換 / コラーゲン / リーディングセル / 細胞外基質 / 上皮間葉移行 / 浸潤 / Hedgehog経路 / Estrogen receptor経路 / 治療標的 / 乳がん / エストロゲンレセプターシグナル / 腫瘍形成能 / 増殖能 / 浸潤能 / CD24分子 / ヘッジホッグシグナル / 包括的乳癌治療法 / 癌幹細胞 / Hedgehogシグナル / エストロゲンレセプター / 乳癌 / 膵癌特異的代謝産物 Less
  • Research Projects

    (19 results)
  • Co-Researchers

    (26 People)
  •  CAFを標的とした癌免疫の再活性化メカニズムの解明Principal Investigator

    • Principal Investigator
      白羽根 健吾
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  phenotypeに応じた膵癌の免疫微小環境の腫瘍内不均一性の解明Principal Investigator

    • Principal Investigator
      白羽根 健吾
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Gene expression mapping of esophageal cancer microenvironment by spatial transcriptomics

    • Principal Investigator
      INOUE Shigetaka
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Development of biomarkers target on exosomes which derived from stromal cells in premalignant microenvironment.

    • Principal Investigator
      MIYASAKA Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  New drug discovery screening targeting autophagy

    • Principal Investigator
      NAKATA Kohei
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of therapeutic agent targeting desmoplasia in pancreatic cancer and novel drug delivery systemPrincipal Investigator

    • Principal Investigator
      SHIRAHANE Kengo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  A novel treatment of pancreatic cancer through microRNA management using a drug delivery system by artificial virus.

    • Principal Investigator
      NAGAI Eishi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  A new strategy for improving the efficacy of the conventional therapy of pancreatic cancer by remodeling its microenvironment

    • Principal Investigator
      TANAKA Masao
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Identifying the leading cell for the invasion of pancreatic cancer

    • Principal Investigator
      TANAKA Masao
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Identification of the key stromal cell responsible for desmoplasia of pancreatic cancer, elucidation of the origin of it, and regulation of its function

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of nanocapsule containing MRI contrast agent effective for early diagnosis of pancreatic cancer

    • Principal Investigator
      SAKAI Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University
  •  The development of molecular imaging based on the novel artificial virus and the application to the individual therapy for pancreatic cancer

    • Principal Investigator
      OHUCHIDA Kenoki
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  The role of autophagy in tumor-stromal cell interaction

    • Principal Investigator
      NAKATA Kohei
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  comprehensive breast cancer therapy targeting both estrogen receptor and Hedgehog signaling pathways

    • Principal Investigator
      TANAKA Haruo
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  Elucidation and examination of the role and the clinical meaning of mesenchymal stem cells (MSC) in breast cancer distant metastases.Principal Investigator

    • Principal Investigator
      SHIRAHANE KENGO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  癌関連星細胞を標的とした新規膵癌治療戦略の開発

    • Principal Investigator
      大内田 研宙
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  メタボロミクスによる膵癌特異的代謝物の同定と膵液診断への展開

    • Principal Investigator
      TANAKA Masao
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  人工ウイルスを用いた新規早期ガン診断システムの構築

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Identification of the niche cells interacting with cancer stem cells and elucidation of their functions in breast cancerPrincipal Investigator

    • Principal Investigator
      SHIRAHANE Kengo
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  • 1.  OHUCHIDA Kenoki (20452708)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  TANAKA Masao (30163570)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  MORIYAMA Taiki (70586859)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TOMINAGA Yohei (90304823)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  鬼丸 学 (80529876)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  NABAE Toshinaga (10467889)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  OHTSUKA Takao (20372766)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  NAGAI Eishi (30264021)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  NAKATA Kohei (30419569)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  MIZUMOTO Kazuhiro (90253418)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  EGAMI Takuya (40507787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  INOUE Shigetaka (00529802)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MIYASAKA Yoshihiro (40507795)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  当間 宏樹 (80437780)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  TANAKA Haruo (90585746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KATANO Mitsuo (10145203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ONISHI Hideya (30553276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NAKANO Kenji (00315061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SOHZAKI Masae (40610613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KUBO Makoto (60403961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SAKAI Hiroshi (80611665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TAKAHATA Shunichi (50437779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  UEDA Junji (90529801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  MANABE Tatsuya (60546464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  岩本 千佳 (10752842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  田村 公二 (90909582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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