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UMEYAMA Hideaki  梅山 秀明

ORCIDConnect your ORCID iD *help
… Alternative Names

梅山 秀明  ウメヤマ ヒデアキ

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Researcher Number 20050619
External Links
Affiliation (Current) 2025: 北里大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help 2011: 北里大学, 薬学部, 教授
2006 – 2007: 北里大学, 薬学部, 教授
2000 – 2004: 北里大学, 薬学部, 教授
1999: 北里大学, 薬学部・生物分子設計学講座, 教授
1995: 北里大学, 薬学部, 教授
1989: 北里大学, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Biological Sciences / Applied genomics
Except Principal Investigator
Biological Sciences / Living organism molecular science / Experimental pathology / Biophysics / Physical pharmacy
Keywords
Principal Investigator
CASP / FAMS / CAFASP / タンパク質 / Protein / FAMSBASE / GTOP / 遺伝子 / 立体構造 / ゲノム … More / ホモロジーモデリング / バイオインフォマティックス / Mouse / Rat / Database / Critical Assessment / Interaction / Structure Prediction / Complex / CAPRI / マウス / ラット / データベース / prediction / structure / protein / 機能進化解析 / タンパク質立体構造予測 / タンパク質データベ-ス / プロテオーム / FAMS、FAMSBASE / アライメント / コンピュータ解析 / 予測 / 蛋白質 / ソフトウェア開発効率化 / 情報システム … More
Except Principal Investigator
FAMSBASE / 膜タンパク質 / モデリング / 立体構造予測 / 立体構造 / タンパク質 / 計算生物学 / Molecular simulation / Homology modeling / Critical Assessment of Techniques for Protein Structure Prediction / Protein structure prediction / Genome function prediction / Bioinformatics / Computational biology / 3Dキーノート / 国際予測コンテストCASP4 / らん藻ゲノム / SOSUI / Gtop / 予測生物学 / アブイニシオ / シミュレーション / CASP5 / 分子シミュレーション / ホモロジーモデリング / 構造予測国際コンテストCASP / タンパク質立体構造予測 / ゲノム機能予測 / 生命情報科学 / Module / Threading / principal variety of protein folds / Structural prediction / Structural comparison / Principle of architecture / Three-dimensional structure / Protein / 膜蛋白質 / 相同蛋白質 / タンパク質デザイン / 構造分類 / 蛋白質 / リゾチウム / キメラタンパク / ファージディスプレイ / 立体構造比較 / スレッティング / モジュール / スレッディング / 立体構造基本型 / 構造予測 / 構造比較 / 構築原理 / ケミカルバイォロジー / 結合タンパク質 / 標的分子 / ケミカルバイオロジー / 天然物 / 感染症 / 欠損株 / 線溶 / 凝固 / ショック / 治療 / 敗血症 / システインプロテアーゼ / 敗血性ショック / 血管漏出 / 阻害剤 / プロテアーゼ / 黄色ブドウ球菌 / タンパク質分類 / 機能予測 / 分子進化 / 偽遺伝子 / データベース構築 / ホモロジー検索 / 局所構造 / ドメイン / 選択的スプライシング / ゲノム情報解析 / プロテオミックス / プロテオーム / 機能ゲノミックス / 構造ゲノミックス / タンパク質立体構造 / ゲノム情報 / 構造生物学 / セリンプロテア-ゼ / 分子動力学 / タンパク質工学 Less
  • Research Projects

    (10 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (27 People)
  •  THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS

    • Principal Investigator
      TOMODA Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Kitasato University
  •  Development of gram-positive bacteria sepsis therapy by inhibition of bacterial proteases.

    • Principal Investigator
      IMAMURA Takahisa
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kumamoto University
  •  Construction of Database of Rat and Mouse Genes for Three Dimensional Monomer and Complex Protein StructurePrincipal Investigator

    • Principal Investigator
      UMEYAMA Hideaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied genomics
    • Research Institution
      Kitasato University
  •  Genome wide protein structure and function prediction database using homology modellingPrincipal Investigator

    • Principal Investigator
      UMEYAMA Hideaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  ゲノム情報からのタンパク質構造の分類と予測

    • Principal Investigator
      西川 建
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
  •  ホモロジーモデリングの手法の開発とデータベース構築Principal Investigator

    • Principal Investigator
      梅山 秀明
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  the maintenance and circulation of protein higher-order structural information and the evaluation of prediction information

    • Principal Investigator
      GO Mitiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  プロテオーム時代の計算情報生物学

    • Principal Investigator
      GO Mitiko
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Nagoya University
  •  Protein structure, comparison, prediction, and design

    • Principal Investigator
      GO Nobuhiro, 野口 俊之
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KYOTO UNIVERSITY
      Nagoya University
  •  タンパク質工学への分子動力学の適用

    • Principal Investigator
      小杉 節子
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kitasato University

All 2008 2007 2005 2004 2003 2002 2001

All Journal Article Presentation Book

  • [Book] バイオデータベースとウェブッールの手取り足取り活用法2002

    • Author(s)
      岩舘満雄, 梅山秀明(分担執筆)
    • Total Pages
      203
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] Bioinformatics based ligand-docking and in-silico screening2008

    • Author(s)
      Daisuke Takaya, Mayuko Taked a-Shitaka, Genki Terashi, Kazuhiko Kanou, Mitsuo Iwadate and Hideaki Umeyama
    • Journal Title

      Chem.Pharm.Bull 56(5)(In press)

    • NAID

      110006664006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] Dynamic interaction among the platform domain and two membrane-proximal immunoglobulin-like domains of class I major histocompatibility complex: normal mode analysis2008

    • Author(s)
      Hiroyuki Nojima, Mayuko Taked a-Shitaka, Kazuhiko Kanou, Kenshu Kamiya, Hideaki Umeyama
    • Journal Title

      Chem.Pharm.Bull. 565)(In press)

    • NAID

      110006663983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] 計算科学によるタンパク質問相互作用解析2007

    • Author(s)
      竹田-志鷹 真由子, 寺師 玄記, 梅山 秀明
    • Journal Title

      生命の科学 58(5)

      Pages: 338-341

    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] Protein Structure Prediction in Structure Based Drug Design2007

    • Author(s)
      Takeda-Shitaka M., Terashi G., Chiba C., Takaya D., Umeyama H.
    • Journal Title

      Medicinal Chmistry 2

      Pages: 191-201

    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] Identification of amino acid residues of Salmonella SlyA that are critical for transcriptional regulation2007

    • Author(s)
      Okada N, Oi Y, Takeda-Shitaka M, Kanou K, Umeyama H, Haneda T, Miki T, Hosoya S, Danbara H.
    • Journal Title

      Microbiology 153

      Pages: 548-60

    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] Fams-ace:a combined method to select the best model after remodeling all server models2007

    • Author(s)
      Terashi G, Takeda-Shitaka M, Kanou K, Iwadate M, Takaya D, Hosoi A, Ohta K, Umeyama H
    • Journal Title

      Proteins 69

      Pages: 98-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] The SKE-DOCK server and human teams based on a combined method of shape complementarity and free energy estimation2007

    • Author(s)
      Genki Terashi, Mayuko Takeda-Shitaka, Kazuhiko Kanou, Mitsuo Iwadate, Daisuke Takaya, Hideaki Umeyama.
    • Journal Title

      Proteins 69(4)

      Pages: 866-872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310139
  • [Journal Article] A fully automated homology modeling system for protein-protein complex structure2005

    • Author(s)
      Mayuko Takeda-Shitaka, Genki Terashi, Chieko Chiba, Daisuke Takaya, Hideaki Umeyama
    • Journal Title

      Medicinal Chemistry (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Protein structure prediction in CASP6 using CHIMERA and FAMS2005

    • Author(s)
      Mayuko Takeda-Shitaka, Genki Terashi, Daisuke Takaya, Kazuhiko Kanou, Mitsuo Iwadate, Hideaki Umeyama
    • Journal Title

      Proteins (Published on line)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Searching for protein-protein interaction sites and protein-protein docking by the methods of molecular dynamics, grid scoring and the pair-wise interaction potential of amino acid residues.2005

    • Author(s)
      Terashi G, Takeda-Shitaka M, Takaya D, Umeyama H.
    • Journal Title

      Proteins 60

      Pages: 289-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Protein structure prediction in CASP6 using CHIMERA and FAMS2005

    • Author(s)
      Mayuko Takeda-Shitaka, Genki Terashi, Daisuke Takaya, Kazuhiko Kanou, Mitsuo Iwadate, Hideaki Umeyama
    • Journal Title

      Proteins Published online

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Searching for protein-protein interaction sites and protein-protein docking by the methods of molecular dynamics, grid scoring and the pair-wise interaction potential of amino acid residues.2005

    • Author(s)
      Terashi G, Takeda-Shitaka M, Takaya D, Umeyama H
    • Journal Title

      Proteins 60

      Pages: 289-295

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Remarkably different structures and reaction mechanisms of ketoreductases for the opposite stereochemical control in the biosynthesis of BIQ antibiotics.2004

    • Author(s)
      著者11人9番目に梅山秀明
    • Journal Title

      Bioorg Med Chem. 12

      Pages: 5917-5927

    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Evaluation of homology modeling of the severe acute respiratory syndrome (SARS) coronavirus main protease for structure based drug design2004

    • Author(s)
      Takeda-Shitaka M, Nojima H, Takaya D, Kanou K, Iwadate M, Umeyama
    • Journal Title

      Chem Pharm Bull (Tokyo). 52

      Pages: 643-645

    • NAID

      110003615633

    • Data Source
      KAKENHI-PROJECT-15013251
  • [Journal Article] Enlarged FAMSBASE : 3D protein structure models of genome sequences for 41 species2003

    • Author(s)
      Yamaguchi, A., Iwadate, M., Suzuki, E., Yura, K., Kawakita, S., Umeyama.H., Go, M.
    • Journal Title

      Nucleic Acids Research 31(1)

      Pages: 463-468

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] FAMS : homology modeling of three-dimensional structures of proteins from sequences2003

    • Author(s)
      Iwadate, M., Umeyama, H.
    • Journal Title

      Seibutsu Butsuri 42(6)

      Pages: 282-284

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] Evaluation of the third solvent clusters fitting procedure for the prediction of protein-protein interactions based on the results at the CAPRI blind docking study2003

    • Author(s)
      Komatsu, K., Kurihara, Y., Iwadate, M., Takeda-Shitaka, M., Umeyama, H.
    • Journal Title

      PROTEINS, Structure, Function and Genetics 52(1)

      Pages: 15-18

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] Toward a functional prediction of organism genomes2002

    • Author(s)
      Umeyama, H., Ebisawa, K.
    • Journal Title

      Joho-shori 43(1)

      Pages: 29-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] A step-by-step instruction how to use bio-database and web tool2002

    • Author(s)
      Iwadate, M., Umeyama, H.
    • Journal Title

      Yodosya Co., Ltd.

      Pages: 203-203

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] FAMS : 配列からタンパク質立体構造ホモロジーモデリング2002

    • Author(s)
      岩舘満雄, 梅山秀明
    • Journal Title

      生物物理 42(6)

      Pages: 282-284

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] 生物ゲノムの機能予測を目指して2002

    • Author(s)
      梅山秀明, 海老沢計慶
    • Journal Title

      情報処理 43(1)

      Pages: 29-35

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] タンパク質立体構造の自動モデリングと創薬への応用2001

    • Author(s)
      梅山秀明, 海老沢計慶
    • Journal Title

      ファルマシア 37(12)

      Pages: 1099-1103

    • NAID

      110003660812

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] An auto-modeling in protein 3D structure and an application of drug development2001

    • Author(s)
      Umeyama, H., Ebisawa, K.
    • Journal Title

      Farumashia 37(12)

      Pages: 1099-1103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] Comparative modeling of CAFASP2 competition2001

    • Author(s)
      Iwadate, M., Ebisawa, K., Umeyama, H.
    • Journal Title

      Chem-Bio Informatics Journal 1(4)

      Pages: 136-148

    • NAID

      130004138107

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] Comparative modeling of CAFASP2 competition2001

    • Author(s)
      Iwadate, M., Ebisawa, K., Umeyama, H.
    • Journal Title

      Chem-Bio lnformatics Journal 1(4)

      Pages: 136-148

    • NAID

      130004138107

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] タンパク質立体構造の自動モデリング2001

    • Author(s)
      梅山秀明, 岩舘満雄
    • Journal Title

      実験医学 増刊 ゲノム医科学と基礎からのバイオインフォマティックス 19(11)

      Pages: 180-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Journal Article] An automatic modeling of protein 3D structure2001

    • Author(s)
      Umeyama, H., Iwadate, M.
    • Journal Title

      Jikken Igaku, special edition, Genome medical science and basic bioinformatics 19(11)

      Pages: 180-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207002
  • [Presentation] タンパク質モデリングと生物分子設計2007

    • Author(s)
      岩舘 満雄、加納 和彦、寺師 玄記、高谷 大輔、竹田-志鷹 真由子、梅山 秀明
    • Organizer
      BMB2007第30回日本分子生物学会年会、第80回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-18310139
  • [Presentation]2007

    • Author(s)
      竹田-志鷹 真由子、寺師 玄記、加納 和彦、岩舘 満雄、高谷 大輔、酒井 博子、梅山 秀明
    • Organizer
      第35回構造活性相関シンポジウム
    • Place of Presentation
      京都大学百周年記念ホール
    • Year and Date
      2007-11-16
    • Data Source
      KAKENHI-PROJECT-18310139
  • 1.  NISHIKAWA Ken (10093288)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  MITAKU Shigeki (10107542)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KIDERA Akinori (00186280)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  IWADATE Mitsuo (10327447)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 5.  FUKAMI Kaoru (20225494)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  GO Mitiko (70037290)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  WAKO Hiroshi (60158607)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  GO Nobuhiro (50011549)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  IMAMURA Takahisa (20176499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TOMODA Hiroshi (70164043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  INOKOSHI Junji (30151640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  UCHIDA Ryuji (60280632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOYAMA Nobuhiro (60439156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAGAMITSU Toru (90300756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YURA Kei (50252226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOMO Tetsuya (00222399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ISHIMORI Koichiro (20192487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKEDA Mayuko (70265718)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 19.  TERASHI Genki (40383658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 20.  KANOU Kazuhiko (00383654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 21.  小杉 節子 (50050711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  中村 春木 (80134485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  太田 元規 (40290895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  野口 俊之 (90172775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  森島 績 (50026093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  熊谷 泉 (10161689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  諏訪 牧子 (30242241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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