UMEYAMA Hideaki 梅山秀明

… Alternative Names

梅山秀明ウメヤマヒデアキ

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Researcher Number	20050619
External Links
Affiliation (Current)	2025: 北里大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help	2011: 北里大学, 薬学部, 教授 2006 – 2007: 北里大学, 薬学部, 教授 2000 – 2004: 北里大学, 薬学部, 教授 1999: 北里大学, 薬学部・生物分子設計学講座, 教授 1995: 北里大学, 薬学部, 教授 1989: 北里大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Biological Sciences / Applied genomics Except Principal Investigator Biological Sciences / Living organism molecular science / Experimental pathology / Biophysics / Physical pharmacy
Keywords	Principal Investigator CASP / FAMS / CAFASP / タンパク質 / Protein / FAMSBASE / GTOP / 遺伝子 / 立体構造 / ゲノム … More / ホモロジーモデリング / バイオインフォマティックス / Mouse / Rat / Database / Critical Assessment / Interaction / Structure Prediction / Complex / CAPRI / マウス / ラット / データベース / prediction / structure / protein / 機能進化解析 / タンパク質立体構造予測 / タンパク質データベ-ス / プロテオーム / FAMS、FAMSBASE / アライメント / コンピュータ解析 / 予測 / 蛋白質 / ソフトウェア開発効率化 / 情報システム … More Except Principal Investigator FAMSBASE / 膜タンパク質 / モデリング / 立体構造予測 / 立体構造 / タンパク質 / 計算生物学 / Molecular simulation / Homology modeling / Critical Assessment of Techniques for Protein Structure Prediction / Protein structure prediction / Genome function prediction / Bioinformatics / Computational biology / 3Dキーノート / 国際予測コンテストCASP4 / らん藻ゲノム / SOSUI / Gtop / 予測生物学 / アブイニシオ / シミュレーション / CASP5 / 分子シミュレーション / ホモロジーモデリング / 構造予測国際コンテストCASP / タンパク質立体構造予測 / ゲノム機能予測 / 生命情報科学 / Module / Threading / principal variety of protein folds / Structural prediction / Structural comparison / Principle of architecture / Three-dimensional structure / Protein / 膜蛋白質 / 相同蛋白質 / タンパク質デザイン / 構造分類 / 蛋白質 / リゾチウム / キメラタンパク / ファージディスプレイ / 立体構造比較 / スレッティング / モジュール / スレッディング / 立体構造基本型 / 構造予測 / 構造比較 / 構築原理 / ケミカルバイォロジー / 結合タンパク質 / 標的分子 / ケミカルバイオロジー / 天然物 / 感染症 / 欠損株 / 線溶 / 凝固 / ショック / 治療 / 敗血症 / システインプロテアーゼ / 敗血性ショック / 血管漏出 / 阻害剤 / プロテアーゼ / 黄色ブドウ球菌 / タンパク質分類 / 機能予測 / 分子進化 / 偽遺伝子 / データベース構築 / ホモロジー検索 / 局所構造 / ドメイン / 選択的スプライシング / ゲノム情報解析 / プロテオミックス / プロテオーム / 機能ゲノミックス / 構造ゲノミックス / タンパク質立体構造 / ゲノム情報 / 構造生物学 / セリンプロテア-ゼ / 分子動力学 / タンパク質工学 Less

THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS
- Principal Investigator
  
  TOMODA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kitasato University
Development of gram-positive bacteria sepsis therapy by inhibition of bacterial proteases.
- Principal Investigator
  
  IMAMURA Takahisa
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kumamoto University
Construction of Database of Rat and Mouse Genes for Three Dimensional Monomer and Complex Protein StructurePrincipal Investigator
- Principal Investigator
  
  UMEYAMA Hideaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kitasato University
Genome wide protein structure and function prediction database using homology modellingPrincipal Investigator
- Principal Investigator
  
  UMEYAMA Hideaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
ゲノム情報からのタンパク質構造の分類と予測
- Principal Investigator
  
  西川建
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
ホモロジーモデリングの手法の開発とデータベース構築Principal Investigator
- Principal Investigator
  
  梅山秀明
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
the maintenance and circulation of protein higher-order structural information and the evaluation of prediction information
- Principal Investigator
  
  GO Mitiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
プロテオーム時代の計算情報生物学
- Principal Investigator
  
  GO Mitiko
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
Protein structure, comparison, prediction, and design
- Principal Investigator
  
  GO Nobuhiro, 野口俊之
- Project Period (FY)
  1995 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  KYOTO UNIVERSITY
  Nagoya University
タンパク質工学への分子動力学の適用
- Principal Investigator
  
  小杉節子
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kitasato University

All 2008 2007 2005 2004 2003 2002 2001

All Journal Article Presentation Book

[Book] バイオデータベースとウェブッールの手取り足取り活用法2002
- Author(s)
  岩舘満雄, 梅山秀明(分担執筆)
- Total Pages
  203
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] Bioinformatics based ligand-docking and in-silico screening2008
- Author(s)
  Daisuke Takaya, Mayuko Taked a-Shitaka, Genki Terashi, Kazuhiko Kanou, Mitsuo Iwadate and Hideaki Umeyama
- Journal Title
  
  Chem.Pharm.Bull 56(5)(In press)
- NAID
  110006664006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] Dynamic interaction among the platform domain and two membrane-proximal immunoglobulin-like domains of class I major histocompatibility complex: normal mode analysis2008
- Author(s)
  Hiroyuki Nojima, Mayuko Taked a-Shitaka, Kazuhiko Kanou, Kenshu Kamiya, Hideaki Umeyama
- Journal Title
  
  Chem.Pharm.Bull. 565)(In press)
- NAID
  110006663983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] 計算科学によるタンパク質問相互作用解析2007
- Author(s)
  竹田-志鷹真由子, 寺師玄記, 梅山秀明
- Journal Title
  
  生命の科学 58(5)
  
  Pages: 338-341
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] Protein Structure Prediction in Structure Based Drug Design2007
- Author(s)
  Takeda-Shitaka M., Terashi G., Chiba C., Takaya D., Umeyama H.
- Journal Title
  
  Medicinal Chmistry 2
  
  Pages: 191-201
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] Identification of amino acid residues of Salmonella SlyA that are critical for transcriptional regulation2007
- Author(s)
  Okada N, Oi Y, Takeda-Shitaka M, Kanou K, Umeyama H, Haneda T, Miki T, Hosoya S, Danbara H.
- Journal Title
  
  Microbiology 153
  
  Pages: 548-60
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] Fams-ace:a combined method to select the best model after remodeling all server models2007
- Author(s)
  Terashi G, Takeda-Shitaka M, Kanou K, Iwadate M, Takaya D, Hosoi A, Ohta K, Umeyama H
- Journal Title
  
  Proteins 69
  
  Pages: 98-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] The SKE-DOCK server and human teams based on a combined method of shape complementarity and free energy estimation2007
- Author(s)
  Genki Terashi, Mayuko Takeda-Shitaka, Kazuhiko Kanou, Mitsuo Iwadate, Daisuke Takaya, Hideaki Umeyama.
- Journal Title
  
  Proteins 69(4)
  
  Pages: 866-872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310139
[Journal Article] A fully automated homology modeling system for protein-protein complex structure2005
- Author(s)
  Mayuko Takeda-Shitaka, Genki Terashi, Chieko Chiba, Daisuke Takaya, Hideaki Umeyama
- Journal Title
  
  Medicinal Chemistry (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Protein structure prediction in CASP6 using CHIMERA and FAMS2005
- Author(s)
  Mayuko Takeda-Shitaka, Genki Terashi, Daisuke Takaya, Kazuhiko Kanou, Mitsuo Iwadate, Hideaki Umeyama
- Journal Title
  
  Proteins (Published on line)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Searching for protein-protein interaction sites and protein-protein docking by the methods of molecular dynamics, grid scoring and the pair-wise interaction potential of amino acid residues.2005
- Author(s)
  Terashi G, Takeda-Shitaka M, Takaya D, Umeyama H.
- Journal Title
  
  Proteins 60
  
  Pages: 289-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Protein structure prediction in CASP6 using CHIMERA and FAMS2005
- Author(s)
  Mayuko Takeda-Shitaka, Genki Terashi, Daisuke Takaya, Kazuhiko Kanou, Mitsuo Iwadate, Hideaki Umeyama
- Journal Title
  
  Proteins Published online
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Searching for protein-protein interaction sites and protein-protein docking by the methods of molecular dynamics, grid scoring and the pair-wise interaction potential of amino acid residues.2005
- Author(s)
  Terashi G, Takeda-Shitaka M, Takaya D, Umeyama H
- Journal Title
  
  Proteins 60
  
  Pages: 289-295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Remarkably different structures and reaction mechanisms of ketoreductases for the opposite stereochemical control in the biosynthesis of BIQ antibiotics.2004
- Author(s)
  著者11人9番目に梅山秀明
- Journal Title
  
  Bioorg Med Chem. 12
  
  Pages: 5917-5927
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Evaluation of homology modeling of the severe acute respiratory syndrome (SARS) coronavirus main protease for structure based drug design2004
- Author(s)
  Takeda-Shitaka M, Nojima H, Takaya D, Kanou K, Iwadate M, Umeyama
- Journal Title
  
  Chem Pharm Bull (Tokyo). 52
  
  Pages: 643-645
- NAID
  110003615633
- Data Source
  KAKENHI-PROJECT-15013251
[Journal Article] Enlarged FAMSBASE : 3D protein structure models of genome sequences for 41 species2003
- Author(s)
  Yamaguchi, A., Iwadate, M., Suzuki, E., Yura, K., Kawakita, S., Umeyama.H., Go, M.
- Journal Title
  
  Nucleic Acids Research 31(1)
  
  Pages: 463-468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] FAMS : homology modeling of three-dimensional structures of proteins from sequences2003
- Author(s)
  Iwadate, M., Umeyama, H.
- Journal Title
  
  Seibutsu Butsuri 42(6)
  
  Pages: 282-284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] Evaluation of the third solvent clusters fitting procedure for the prediction of protein-protein interactions based on the results at the CAPRI blind docking study2003
- Author(s)
  Komatsu, K., Kurihara, Y., Iwadate, M., Takeda-Shitaka, M., Umeyama, H.
- Journal Title
  
  PROTEINS, Structure, Function and Genetics 52(1)
  
  Pages: 15-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] Toward a functional prediction of organism genomes2002
- Author(s)
  Umeyama, H., Ebisawa, K.
- Journal Title
  
  Joho-shori 43(1)
  
  Pages: 29-35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] A step-by-step instruction how to use bio-database and web tool2002
- Author(s)
  Iwadate, M., Umeyama, H.
- Journal Title
  
  Yodosya Co., Ltd.
  
  Pages: 203-203
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] FAMS : 配列からタンパク質立体構造ホモロジーモデリング2002
- Author(s)
  岩舘満雄, 梅山秀明
- Journal Title
  
  生物物理 42(6)
  
  Pages: 282-284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] 生物ゲノムの機能予測を目指して2002
- Author(s)
  梅山秀明, 海老沢計慶
- Journal Title
  
  情報処理 43(1)
  
  Pages: 29-35
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] タンパク質立体構造の自動モデリングと創薬への応用2001
- Author(s)
  梅山秀明, 海老沢計慶
- Journal Title
  
  ファルマシア 37(12)
  
  Pages: 1099-1103
- NAID
  110003660812
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] An auto-modeling in protein 3D structure and an application of drug development2001
- Author(s)
  Umeyama, H., Ebisawa, K.
- Journal Title
  
  Farumashia 37(12)
  
  Pages: 1099-1103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] Comparative modeling of CAFASP2 competition2001
- Author(s)
  Iwadate, M., Ebisawa, K., Umeyama, H.
- Journal Title
  
  Chem-Bio Informatics Journal 1(4)
  
  Pages: 136-148
- NAID
  130004138107
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] Comparative modeling of CAFASP2 competition2001
- Author(s)
  Iwadate, M., Ebisawa, K., Umeyama, H.
- Journal Title
  
  Chem-Bio lnformatics Journal 1(4)
  
  Pages: 136-148
- NAID
  130004138107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] タンパク質立体構造の自動モデリング2001
- Author(s)
  梅山秀明, 岩舘満雄
- Journal Title
  
  実験医学増刊ゲノム医科学と基礎からのバイオインフォマティックス 19(11)
  
  Pages: 180-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Journal Article] An automatic modeling of protein 3D structure2001
- Author(s)
  Umeyama, H., Iwadate, M.
- Journal Title
  
  Jikken Igaku, special edition, Genome medical science and basic bioinformatics 19(11)
  
  Pages: 180-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12207002
[Presentation] タンパク質モデリングと生物分子設計2007
- Author(s)
  岩舘満雄、加納和彦、寺師玄記、高谷大輔、竹田-志鷹真由子、梅山秀明
- Organizer
  BMB2007第30回日本分子生物学会年会、第80回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18310139
[Presentation]2007
- Author(s)
  竹田-志鷹真由子、寺師玄記、加納和彦、岩舘満雄、高谷大輔、酒井博子、梅山秀明
- Organizer
  第35回構造活性相関シンポジウム
- Place of Presentation
  京都大学百周年記念ホール
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18310139

1. NISHIKAWA Ken (10093288)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. MITAKU Shigeki (10107542)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KIDERA Akinori (00186280)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. IWADATE Mitsuo (10327447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. FUKAMI Kaoru (20225494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. GO Mitiko (70037290)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. WAKO Hiroshi (60158607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. GO Nobuhiro (50011549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. IMAMURA Takahisa (20176499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOMODA Hiroshi (70164043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. INOKOSHI Junji (30151640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UCHIDA Ryuji (60280632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOYAMA Nobuhiro (60439156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAGAMITSU Toru (90300756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YURA Kei (50252226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOMO Tetsuya (00222399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ISHIMORI Koichiro (20192487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKEDA Mayuko (70265718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
19. TERASHI Genki (40383658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. KANOU Kazuhiko (00383654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. 小杉節子 (50050711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中村春木 (80134485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 太田元規 (40290895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 野口俊之 (90172775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 森島績 (50026093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 熊谷泉 (10161689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 諏訪牧子 (30242241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

UMEYAMA Hideaki 梅山 秀明

梅山 秀明 ウメヤマ ヒデアキ

Research Projects

Research Products

Co-Researchers

THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gram-positive bacteria sepsis therapy by inhibition of bacterial proteases.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of Database of Rat and Mouse Genes for Three Dimensional Monomer and Complex Protein StructurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genome wide protein structure and function prediction database using homology modellingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム情報からのタンパク質構造の分類と予測

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ホモロジーモデリングの手法の開発とデータベース構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

the maintenance and circulation of protein higher-order structural information and the evaluation of prediction information

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プロテオーム時代の計算情報生物学

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein structure, comparison, prediction, and design

Principal Investigator

Project Period (FY)

Research Category

Research Institution

タンパク質工学への分子動力学の適用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] バイオデータベースとウェブッールの手取り足取り活用法2002

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Bioinformatics based ligand-docking and in-silico screening2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dynamic interaction among the platform domain and two membrane-proximal immunoglobulin-like domains of class I major histocompatibility complex: normal mode analysis2008

Author(s)

Journal Title

NAID

Data Source

UMEYAMA Hideaki 梅山秀明

梅山秀明ウメヤマヒデアキ