higashida haruhiro 東田陽博

… Alternative Names

HIGASHIDA Haruhiro 東田陽博

東田陽博ヒガシダヒロハル

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Researcher Number	30093066
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Affiliation (Current)	2025: 金沢大学, 子どものこころの発達研究センター, 協力研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢大学, 子どものこころの発達研究センター, 協力研究員 2020 – 2021: 金沢大学, 子どものこころの発達研究センター, 特任教授 2015 – 2018: 金沢大学, 子どものこころの発達研究センター, 特任教授 2013: 金沢大学, 子どものこころの発達研究センター, 特任教授 2012 – 2013: 金沢大学, 子供のこころ発達研究センター, 教授 … More 2008 – 2013: Kanazawa University, 医学系, 教授 2007: 金沢大学, 医学系・研究科, 教授 2007: 金沢大学, 大学院・医学系研究科, 教授 2003 – 2007: 金沢大学, 医学系研究科, 教授 2006: 金沢大学, 医学(系)研究科(研究院), 教授 2000 – 2004: 金沢大学, 大学院・医学系研究科, 教授 1997 – 2000: 金沢大学, 医学部, 教授 1993 – 1995: 金沢大学, 医学部, 教授 1988 – 1991: 金沢大学, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Biological Sciences / Neuroscience in general / General physiology Except Principal Investigator Biological Sciences / Basic Section 58070:Lifelong developmental nursing-related / Circulatory organs internal medicine / Medical systems / Neurochemistry/Neuropharmacology … More / Basic Section 52030:Psychiatry-related / Medium-sized Section 7:Economics, business administration, and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Psychiatric science / Drug development chemistry / Pain science / Neurochemistry/Neuropharmacology / General physiology / Biophysics / Nerve anatomy/Neuropathology / Applied biochemistry / General physiology / 疼痛学 / Nerve anatomy/Neuropathology / Neurophysiology and muscle physiology Less
Keywords	Principal Investigator NAD / イノシトールリン脂質 / ニュ-ロブラスト-マ / セカンドメッセンジャー / サイクリックADPリボース / 細胞内Ca / イノシト-ルリン酸 / アセチ-ルコリン / CD38 / 神経細胞 … More / 受容体 / 線維細胞 / ラス / セカンドメッセンジャ- / カリウムチャンネル / カリウムイオン / Caシグナリング / ムスカリン受容体 / 大脳 / リアノジン受容体 / Caプール / 伝達物質放出 / 横紋筋 / シナプス形成 / シナプス / Dopamine receptor / Dopamine / Striatum / NG108-15 cells / NAD^+ / Cyclic ADP-ribose / パーキンソン病 / ドーパミン / Ca / ADPR cyclase / Signal transduction / second messenger / Ca pool / cyclic ADP-ribose / Ca signaling / サイクリックADPリボナース / cADPR / ADPRcyclase / 信号伝達機構 / ryanodine receptor / heart / cyclase / cyclic ADP ribose / ADP-ribose / 細胞膜 / ADP環状化酵素 / 心筋 / 環状化酵素 / ADPリボース / 情報伝達機構 / ブラジキニン受容体 / 細胞内カルシウム / K^+チャンネル / ニューロブラストーマ / 遊離促進 / 神経筋接合 / アセチールコリン遊離 / ADPリボシルシクラーゼ / 自閉症 / ADP リボシルシクラーゼ / シグナル伝達 / 脳・神経 / KCNQチャネル / Mチャネル / アセチルコリン / 薄層クロマトグラフィー / 膜分画 / ADPリボシールシクラーゼ / モジュレーター / 膜興奮性 / Kチャネル / GTPアーゼ / Mn流入 / パッチクランプ / 伝達物質遊離 / 終板電位 / ブラジキニン / シナプス伝達 / 分化 / 神経筋シナプス … More Except Principal Investigator オキシトシン / 二酸化チタン / Kv1.2 / Kv1.1 / イオンチャネル / DDS / 遺伝子 / がん治療 / OHラジカル / 超音波照射 / 母親 / 唾液 / ionic channel / 疼痛 / 膜電位依存性カリウムチャネル / Ras-GAP / 自閉症 / オキシトシン受容体 / 生理学 / 循環器 / パッチクランプ / 遺伝子変異 / 発達障害 / 脳発達障害 / カルシウムイオン / CD38 / サイクリックADPリボース / 細胞死 / がん細胞 / ナノ粒子 / 超音波 / ブラジキニン / ス-パ-オキシドジスムタ-ゼ / モデル動物 / アセチルコリン / 化学的神経回路網 / 産後うつ / 発達 / オキシトシンアナログ / 自閉スペクトラム症 / 経済実験 / 昇進 / 競争選好 / 男女間格差 / 概日リズム / 自閉症スペクトラム障害 / 睡眠障害 / バソプレシン / バルプロ酸 / L-カルノシン / jet lag paradigm / 概日リズム障害 / ASDモデルマウス / 自閉症スペクトラム障害（ASD) / 養育 / メンタルヘルス / テストステロン / 父親 / 相互作用 / 母子 / モデルマウス / 臨床試験 / 脳神経疾患 / 視覚野 / 頭頂葉 / 前帯状回 / 背外側前頭前野 / mRNA / オシレーション / 作業記憶 / 遺伝子改変マウス / in situ hybridization / ドーパミン / 黒質 / 大脳皮質 / 遺伝子発現 / 死後脳 / BASE阻害剤 / プロテアソーム阻害剤 / BGT-1 阻害剤 / 分子設計 / 三次元的多様性 / 配座制御 / シクロプロパン / sensory neuron / Pain / nerve injury / 脊髄後退神経節ニューロン / 脊髄後根神経節ニューロン / 末梢神経損傷 / tumor necrosis factor-α / interleukin-6 / pain / 脊髄後根神経節 / カリウムチャネル / 腫瘍壊死因子 / インターロイキン6 / voltage-gated potassium channel / 膜電位依存性K^+チャネル / 膜電位依存性^+チャネル / 膜電位依存性K+チャネル / InsP4 receptor / Receptor-operated Ca influx / Bradykinin / Antisense / Inositol tetrakisphosphate / Ca oscillation / Ras / InsP4 / アンチセンス / 受動体作動性Ca流入 / InsP4受容体 / イノシトール4リン酸 / Caオシレーション / ラス / Cryo-electron microscopy / Molecular biology / Patch clamp / Model channel / Dynamical structure / Higher order structure / Ion channels / 合成チャネル / 電気生理学 / チャネル蛋白質 / クローニング / 動的構造機能連関 / 分子動力学 / クライオ電顕 / 分子生物学 / モデルチャネル / 動的構造 / 高次構造 / 機能解析 / ゼブラフィッシュ / 遺伝性不整脈 / 自閉症／広汎性発達障害 / 神経発生 / ストレス / ストレスホルモン / 攻撃衝動 / 体温制御 / 外側中隔 / 向社会行動 / グリア細胞 / セロトニン / 扁桃体内側核 / 母性行動 / 自閉症スペクトラム / 社会行動 / 情報伝達 / シミュレーション工学 / 再生医学 / 徐脈性不整脈 / 生物学的ペースメーカー / 心筋前駆細胞 / 遺伝子解析 / 先天性徐脈 / 免疫沈降 / エピトーグタグ / リン酸化 / カルシウム / cADPリボース / プロテオミクス / 結合蛋白 / 痛み / 神経損傷 / RNAi / 分子遺伝学 / 遺伝子スクリーニング / 脳下垂体 / cADPcR / Mカリウム電流 / 質量分析 / cADPRアナログ / TRPM2チャネル / NG108-15細胞 / 視床下部 / 二酸化チタン内包リポソーム / ポリアクリル酸 / ラジカル分子 / 生体分子 / 固定化 / アポトーシス / B型肝炎ウィルス / 表面修飾 / キャビテーション / 二酸化チタン粒子 / 高周波数超音波 / 細胞膜損傷 / 分子認識 / 超音波化学 / 5-ALA / センダイウイルス / 膜融合リポソーム / 生体分子の固定化 / 機能性ナノ粒子 / 細胞特異認識 / 光触媒 / カリウム / イオンチャンネル / シナプス / シナプス小胞 / シナプス可塑性 / 伝達物質放出 / プロスタグランジン / 受容体クロ-ニング / 細胞内シグナル伝達 / 神経伝達物質 / オピオイド / ブロスタグランジン / 受容体クローニング / 痛覚 / 一次求心性C線維 / 老化促進モデルマウス / アルツハイマ-病モデル動物 / PGP9.5 / プロテインキナ-ゼC / GABA_A受容体 / ムスカリン性受容体 / グルタミナ-ゼ / アドレナリン受容体 / アセチルコリン受容体 / アルツハイマ-病 / 細胞内代謝 / 受容体 / 伝達機構障害 / アルツハイマー病 Less

社会脳形成における発達期オキシトシンシグナルの機能の解明
- Principal Investigator
  
  辻知陽
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kanazawa University
母子接触時の母親の唾液オキシトシン反応性による新たな産後うつバイオマーカーの開発
- Principal Investigator
  
  南香奈
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Kanazawa University
Elucidation of the mechanism of sleep disorders using mice model of autism spectrum disorder (ASD)
- Principal Investigator
  
  辻隆宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  University of Fukui
Preference for competition, oxytocin, and menstrual cycles
- Principal Investigator
  
  木村寛子 (奥平寛子)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 7:Economics, business administration, and related fields
- Research Institution
  Doshisha University
Fluctuations in the nurturance hormone (oxytocin) and its role in men who become fathers.
- Principal Investigator
  
  Minami Kana
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Kanazawa University
Cognitive Deficits and Oxytocin Signaling in Cortical Parvalbumin Neurons in Schizophrenia
- Principal Investigator
  
  HASHIMOTO TAKANORI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kanazawa University
Medicinal chemical study by the three-dimensional structural diversity-oriented strategy based on the characteristic steric and stereoelectronic features of cyclopropane
- Principal Investigator
  
  SHUTO Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University
Study of novel physiological function by the system with oxytocin and its receptor.
- Principal Investigator
  
  NISHIMORI Katsuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tohoku University
Functional screening and study of genes based on aggressive behavior, which is involved in autism and human developmental disorders.
- Principal Investigator
  
  KOIZUMI Keita
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kanazawa University
Gene analysis for the inherited arrhythmia and functional characterization of disease-causing rare variants by using zebrafish
- Principal Investigator
  
  GAMOU TADATSUGU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University
Activation mechanism of cyclic ADP-ribose-synthesizing enzyme CD38
- Principal Investigator
  
  MINAKO Hashii
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
Gene analysis for the inherited bradyarrhythmia and characterization of cardiosphere-derived cells to create biological pacemakers
- Principal Investigator
  
  HAYASHI Kenshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University
Identification of novel nerve injury-induced proteins and their roles in ion channel modulation and pain transduction
- Principal Investigator
  
  YOKOYAMA Shigeru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Kanazawa University
Two steps screening of autistic genes by using Fly/mouse as model animals.
- Principal Investigator
  
  KOIZUMI Keita
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kanazawa University
細胞外サイクリックADPリボースのセンサー機構
- Principal Investigator
  
  橋井美奈子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Neurochemical studies on molecules involved in social recognition and research on genes and therapy in autism.Principal Investigator
- Principal Investigator
  
  HIGASHIDA Haruhiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
機能性バイオ融合ナノ粒子と超音波化学をカップリングした新規がん治療
- Principal Investigator
  
  清水宣明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
機能性生体分子を配向した光触媒ナノ粒子の創製とその医療応用
- Principal Investigator
  
  清水宣明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
Ionic channel expression in primary afferent Aβ fibers:analysis of regulatory mechanism and therapeutic application to chronic pain
- Principal Investigator
  
  YOKOYAMA Shigeru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kanazawa University
組織認識能を有する二酸化チタン・ナノ粒子の新規がん治療への応用
- Principal Investigator
  
  清水宣明
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Aキナーゼアンカータンパク(AKAP)依存的シナプス後電位:終止の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ラジカルを発生する生体分子融合ナノ粒子による新規がん治療法の確立
- Principal Investigator
  
  清水宣明
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
緩除興奮性シナプス後電位(sEPSP):AKAP依存的終止の分子メカニズム
- Principal Investigator
  
  星直人
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kanazawa University
ラット新生仔脳及びCD38ノックアウトマウス脳のADPリボシルシクラーゼの精製Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  Kanazawa University
機能性バイオ融合ナノ粒子の創製とその医療への応用
- Principal Investigator
  
  清水宣明
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
ADP-ribosyl cyclase coupled with dopamine receptors : Application to Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  HIGASHIDA Haruhiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
Influences of aberrant ionic channel expression in primary afferent Aβ fibers on neuropathic pain
- Principal Investigator
  
  YOKOYAMA Shigeru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
神経細胞でサイクリックADPリボースは真のセカンドメッセンジャーかPrincipal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kanazawa University
伝達物質放出の制御によるシナプス伝達の可塑性
- Principal Investigator
  
  阿部輝雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Niigata University
Molecular Characterization of ADP-ribosyl Cyclase Coupled with ReceptorsPrincipal Investigator
- Principal Investigator
  
  HIGASHIDA Haruhiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
Molecular mechanism of neuropathic pain aberrant expression of voltage-gated sodium and potassium channels
- Principal Investigator
  
  YOKOYAMA Shigeru
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
Coupling between Ras oncogene and inositol tetrakisphosphate-activated Ca influx
- Principal Investigator
  
  HASHII Minako
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  kanazawa University
膜電位依存性カリウムMチャネルの遺伝子クローニングPrincipal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
Purification and cloning of brain isoform of ADP-ribosyl cyclasePrincipal Investigator
- Principal Investigator
  
  HIGASHIDA Haruhiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kanazawa University
ラス(ras)タンパク質によるCaオシレーション・イオンチャンネルの制御Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
ラス(ras)タンパク質によるCaオシレーション・イオンチャンネルの制御Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
ラス(ras)タンパク質によるCaオシレーション・イオンチャンネルの制御Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
PIONEERING RESEARCH ON THE DYNAMICAL ASPECT OF STRUCTURE-FUNTION RELATIONSHIP IN ION CHANNELS
- Principal Investigator
  
  SOKABE Masahiro
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
アルツハイマ-病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
イノシト-ル三リン酸(IP_3)のプレシナプス(伝達物質放出)作用Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
一次求心性C線維の神経回路と機能的意義
- Principal Investigator
  
  熊澤孝朗
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
アルツハイマ-病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
イノシト-ル三リン酸(IP_3)のプレシナプス(伝達物質放出)作用Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
ニュ-ロブラスト-マ・グリオ-マ雑種細胞におけるシナプス形成・伝達機構Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
イノシト-ルリン脂質代謝産物によるK+チャンネルの制御機構Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
アルツハイマー病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
イノシト-ル三リン酸(IP_3)のプレシナプス(伝達物質放出)作用Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
ニューロブラストーマ・グリオーマ雑種細胞によるシナプス形成・伝達機構Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
イノシトールリン脂質代謝産物によるK^+チャンネルの制御機構Principal Investigator
- Principal Investigator
  
  東田陽博
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University

[Book] Autism - A Neurodevelopmental Journey from Genes to Behaviour.2011
- Author(s)
  Higashida H., Munesue T., Yokoyama S., Hashii M., Koizumi K. and Matsushima A (Chpter 10), Edited by Eapen, V.
- Total Pages
  484
- Publisher
  In Tech
- Data Source
  KAKENHI-PROJECT-23500427
[Book] A Missense Mutation in CD38 Associated with Autism Spectrum Disorder in Three Pedigrees. In : Autism-A Neurodevelopmental Journey from Genes to Behaviour(Eapen V, ed.)2011
- Author(s)
  Higashida H, Munesue T, Yokoyama S, Hashii M, Koizumi K, Matsushima A
- Total Pages
  14
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-22590202
[Book] "Autism-A Neurodevelopmental Journey from Genes to Behaviour" (Chapter 10)2011
- Author(s)
  Higashida H, Munesue T, Yokoyama S, Hashii M, Koizumi K. and Matsushima A(Edited by: Eapen V)
- Total Pages
  485
- Publisher
  In Tech
- Data Source
  KAKENHI-PROJECT-23500427
[Book] Neurobiology of the Parental Brain (Chapter IV-23)2008
- Author(s)
  Higashida H, Koizumi K. (10名中6番目), Munesue T. (Edited by Bridges R. S. )
- Total Pages
  550
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-20500323
[Book] Social memory, maternal care, and oxytocin secretion, but not vasopressin release2008
- Author(s)
  Higashida H, Jin D, Liu H, Lopatina O, Yokoyama S, Koizumi K, Hashii M, Islam MS, Hayashi K, Munesue T., Academic Press, San Diego,Neurobiology of the Parental Brain, Bridges, R. S. ed.
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-19200030
[Book] Social memory, mental care and oxytocin, but not vasopressin release, require CD38 in mice. In: Neurobiology of the Parental Mind.2008
- Author(s)
  Higashida, H., et. al.
- Total Pages
  15
- Publisher
  Academic Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Book] Neurobiology of the Parental Brain, Bridges, R. S. ed.2008
- Author(s)
  Higashida, H., …… Yokoyama, S., Koizumi, K., Hashii, M., …… Munesue, T., 他5名
- Publisher
  Academic Press, San Diego
- Data Source
  KAKENHI-PROJECT-19200030
[Book] 脳神経科学(伊藤正男監修)2003
- Author(s)
  東田陽博他
- Publisher
  三輪書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Book] Social memory, mental care and oxytocin, but not vasopressin release ,repuire CD38 in mice. In: Neurobiology of the Parental Mind
- Author(s)
  Higashida, H., et. al.
- Total Pages
  15
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Oral Supplementation with Maca Improves Social Recognition Deficits in the Valproic Acid Animal Model of Autism Spectrum Disorder2023
- Author(s)
  Fu Pinyue、Luo Shuxin、Liu Zhongyu、Furuhara Kazumi、Tsuji Takahiro、Higashida Haruhiro、Yokoyama Shigeru、Zhong Jing、Tsuji Chiharu
- Journal Title
  
  Brain Sciences
  
  Volume: 13 Issue: 2 Pages: 316-316
- DOI
  10.3390/brainsci13020316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07346, KAKENHI-PROJECT-22KJ1469, KAKENHI-PROJECT-22K18540
[Journal Article] Biosynthesis and Function of VIP and Oxytocin: Mechanisms of C-terminal Amidation, Oxytocin Secretion and Transport2023
- Author(s)
  Yonekura Hideto、Kato Ichiro、Yamamoto Yasuhiko、Ikeda Takayuki、Higashida Haruhiro、Okamoto Hiroshi
- Journal Title
  
  Endocrinology
  
  Volume: 164 Issue: 9 Pages: 1-14
- DOI
  10.1210/endocr/bqad121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-21K09031, KAKENHI-PROJECT-21H02695
[Journal Article] Postnatal expression of CD38 in astrocytes regulates synapse formation and adult social memory2023
- Author(s)
  Hattori Tsuyoshi、Cherepanov Stanislav M、Sakaga Ryo、Roboon Jureepon、Nguyen Dinh Thi、Ishii Hiroshi、Takarada‐Iemata Mika、Nishiuchi Takumi、Kannon Takayuki、Hosomichi Kazuyoshi、Tajima Atsushi、Yamamoto Yasuhiko、Okamoto Hiroshi、Sugawara Akira、Higashida Haruhiro、Hori Osamu
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 15 Pages: 1-15
- DOI
  10.15252/embj.2022111247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-18KK0435, KAKENHI-PROJECT-23K05984, KAKENHI-PROJECT-21K06406, KAKENHI-PROJECT-21K06407, KAKENHI-PROJECT-21H02695
[Journal Article] Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice2023
- Author(s)
  Gerasimenko Maria、Higashida Haruhiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14
- DOI
  10.3389/fimmu.2023.1166609
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18540
[Journal Article] Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin2023
- Author(s)
  Cherepanov Stanislav M.、Yuhi Teruko、Iizuka Takashi、Hosono Takashi、Ono Masanori、Fujiwara Hiroshi、Yokoyama Shigeru、Shuto Satoshi、Higashida Haruhiro
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 2 Pages: e0281363-e0281363
- DOI
  10.1371/journal.pone.0281363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18540
[Journal Article] Early-onset of social communication and locomotion activity in F2 pups of a valproic acid-induced mouse model of autism2022
- Author(s)
  Tsuji C, Furuhara K, Mizutani R, Minami K, Fu P, Zhong J, Higashida H, Yokoyama S, Tsuji T.
- Journal Title
  
  Neuroscience letters
  
  Volume: 788 Pages: 136827-136827
- DOI
  10.1016/j.neulet.2022.136827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-22KJ1469
[Journal Article] Receptor for advanced glycation end-products and child neglect in mice: A possible link to postpartum depression2022
- Author(s)
  Higashida H, Gerasimenko M, Yamamoto Y.
- Journal Title
  
  Comprehensive Psychoneuroendocrinology
  
  Volume: 11 Pages: 100146-100146
- DOI
  10.1016/j.cpnec.2022.100146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-21H02695
[Journal Article] Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside2022
- Author(s)
  H. Higashida, K. Furuhara, O. Lopatina, M. Gerasimenko, O. Hori, T. Hattori, Y. Hayashi, S. M. Cherepanov, A. A. Shabalova, A. B. Salmina, K. Minami, T. Yuhi, C. Tsuji, P. Y. Fu, Z. Liu, S. Luo, A. Zhang, S. Yokoyama, S. Shuto, M. Watanabe, K. Fujiwara, S. Munesue, A. Harashima, Y. Yamamoto
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 858070-858070
- DOI
  10.3389/fnins.2022.858070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-19H01014, KAKENHI-PROJECT-21H02695, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-20K07323
[Journal Article] Mitochondrial LETM1 drives ionic and molecular clock rhythms in circadian pacemaker neurons2022
- Author(s)
  Morioka E, Kasuga Y, Kanda Y, Moritama S, Koizumi H, Yoshikawa T, Miura N, Ikeda M, Higashida H, Holmes TC and Ikeda M
- Journal Title
  
  Cell Reports
  
  Volume: 39 Issue: 6 Pages: 110787-110787
- DOI
  10.1016/j.celrep.2022.110787
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06263, KAKENHI-PROJECT-22K06311, KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-22KJ1455, KAKENHI-PROJECT-19K06774
[Journal Article] Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin2022
- Author(s)
  Minami Kana、Yuhi Teruko、Higashida Haruhiro、Yokoyama Shigeru、Tsuji Takahiro、Tsuji Chiharu
- Journal Title
  
  Brain Sciences
  
  Volume: 12 Issue: 9 Pages: 1246-1246
- DOI
  10.3390/brainsci12091246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07346, KAKENHI-PROJECT-22K18540, KAKENHI-PROJECT-22KJ1469, KAKENHI-PROJECT-20K10906
[Journal Article] Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release2022
- Author(s)
  Tsuji Takahiro、Furuhara Kazumi、Gerasimenko Maria、Shabalova Anna、Cherepanov Stanislav M、Minami Kana、Higashida Haruhiro、Tsuji Chiharu
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 4 Pages: 803-803
- DOI
  10.3390/nu14040803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06939, KAKENHI-PROJECT-22K07346, KAKENHI-PROJECT-22KJ1469
[Journal Article] Lipo-oxytocin-1, A Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-lasting Effects on Anxiety-related Behavior and Social Avoidance in CD157 Knockout Mice.2015
- Author(s)
  A. Mizuno, S. M. Cherepanov, Y. Kikuchi, A. Fakhrul, S. Akther, K. Deguchi, T. Yoshihara, K. Ishihara, S. Shuto , H. Higashida
- Journal Title
  
  Brain Sci
  
  Volume: 5 Issue: 1 Pages: 3-13
- DOI
  10.3390/brainsci5010003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-26460499, KAKENHI-PROJECT-15H02495
[Journal Article] Non-synonymous single-nucleotide variations of the human oxytocin receptor gene and autism spectrum disorders: a case-control study in a Japanese population and functional analysis.2013
- Author(s)
  Ma WJ, Hashii M, Munesue T, Hayashi K, Yagi K, Yamagishi M, Higashida H, Yokoyama S.
- Journal Title
  
  Mol Autism
  
  Volume: 4 Issue: 1 Pages: 22-22
- DOI
  10.1186/2040-2392-4-22
- NAID
  120006325350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591078, KAKENHI-PROJECT-24659541, KAKENHI-PROJECT-25293248
[Journal Article] Dopamine-Induced Regulation and Deregulation of the Catabolism of Cyclic ADP-Ribose, an Intrinsic mTOR Signal InhibitorDuring Development in the Rodent Striatum2013
- Author(s)
  Higashida,C., Islam,M.S., Hashii,M., Higashida,H
- Journal Title
  
  Messenger
  
  Volume: 2 Issue: 1 Pages: 33-43
- DOI
  10.1166/msr.2013.1019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] Dopamine release via the vacuolar ATPase V0 sector c-subunit, confirmed in N18 neuroblastoma cells results in behavioral recovery in hemiparkinsonian mice2012
- Author(s)
  Jin,D., Hashii,M., Higashida,H
- Journal Title
  
  Neurochem. Int
  
  Volume: 61 Issue: 6 Pages: 907-912
- DOI
  10.1016/j.neuint.2011.12.021
- NAID
  120004966609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202, KAKENHI-PUBLICLY-23110515, KAKENHI-PROJECT-23590473
[Journal Article] Intracellular calcium concentrations regulated by cyclic ADP-ribose and heat in the mouse hypothalamus2012
- Author(s)
  Liu,H.-X., Hashii,M., Higashida,H
- Journal Title
  
  Messenger
  
  Volume: 1 Issue: 2 Pages: 150-159
- DOI
  10.1166/msr.2012.1015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] A Missense Mutation in CD38 Associated with Autism Spectrum Disorder in Three Pedigrees.In:Eapen,V.,ed. Autism - ANeurodevelopmental Journey from Genes to Behaviour2011
- Author(s)
  Higashida, H., Munesue, T., Hashii,M
- DOI
  10.5772/17774
- ISBN
  9789533074931
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] Ect2, an ortholog of Drosophila's pebble, negatively regulates neurite outgrowth in neuroblastoma x glioma hybrid NG108-15 cells2011
- Author(s)
  Tsuji T, Higashida C, Yoshida Y, Islam MS, Dohmoto M, Koizumi K, Higashida H
- Journal Title
  
  Cell Mol Neurobiol
  
  Volume: 31 Issue: 5 Pages: 663-8
- DOI
  10.1007/s10571-011-9668-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500427
[Journal Article] Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism2011
- Author(s)
  Suda S, Koizumi K , Higashida H, Mori N
- Journal Title
  
  Mol Autism
  
  Volume: 2 Issue: 1 Pages: 14-14
- DOI
  10.1186/2040-2392-2-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500427
[Journal Article] The two genetic variants of CD38 in subjects with autism spectrum disorder and controls.2010
- Author(s)
  Munesue T,,,, Koizumi K(54名中10番目),,,HigashidaH.
- Journal Title
  
  Neuroscience Research
  
  Volume: 67 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Oxytocin Signal and Social Behaviour Comparison among Adult and Infant Oxytocin, Oxytocin Receptor and CD38 Gene Knockout Mice2010
- Author(s)
  Higashida H, Lopatina O, Yoshihara T, Pichugina YA, Soumarokov AA, Munesue T, Minabe Y, Kikuchi M, Ono Y, Korshunova N, Salmina AB.
- Journal Title
  
  J Neuroendocrinol. (in press)
- NAID
  120002561624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Oxytocin Signal and Social Behaviour: Comparison among Adult and Infant Oxytocin, Oxytocin Receptor and CD38 Gene Knockout Mice2010
- Author(s)
  Higashida H, Lopatina O, Yoshihara T, Pichugina YA, Soumarokov AA, Munesue T, Minabe Y, Kikuchi M, Ono Y, Korshunova N, Salmina AB.
- Journal Title
  
  J Neuroendocrinol 22
  
  Pages: 373-379
- NAID
  120002561624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Oxytocininduced elevation of ADP-ribosyl cyclase activity, cyclic ADP-ribose or Ca(2+) concentrations is involved in autoregulation of oxytocin secretion in the hypothalamus and posterior pituitary in male mice2010
- Author(s)
  Lopatina,O.,Liu,H.X.,Amina,S., Hashii,M.,Higashida,H
- Journal Title
  
  Neuropharmacology
  
  Volume: 58 Issue: 1 Pages: 50-55
- DOI
  10.1016/j.neuropharm.2009.06.012
- NAID
  120001451026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] Intracellular Calcium Elevation Induced by Extracellular Application of Cyclic-ADP-Ribose or Oxytocin is Temperature-Sensitive in Rodent NG108-15 Neuronal Cells with or without Exogenous Expression of Human Oxytocin Receptors2010
- Author(s)
  Amina S, Hashii M, Ma WJ, Yokoyama S, Lopatina O, Liu HX, Islam MS, Higashida H.
- Journal Title
  
  J Neuroendocrinol 22
  
  Pages: 460-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Trafficking-Competent KCNQ1 Variably Influences the Function of HERG Long QT Alleles2010
- Author(s)
  Hayashi K, Shuai W, Sakamoto Y, Higashida H, Yamagishi M, Kupershmidt S.
- Journal Title
  
  Heart Rhythm (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Two genetic vaziants of CD38 in subjects with autism spectrum disorder and controls.2010
- Author(s)
  Munesue T, Yokoyama S, Hashii M, Higashida H, et al.
- Journal Title
  
  Neurosci.Res.
  
  Volume: 67 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] オキシトシンとバソプレッシンー2010
- Author(s)
  東田陽博、小泉惠太、吉原亨、棟居俊夫
- Journal Title
  
  社会性認知行動と信頼の神経化学的基盤子どものこころと脳の発達 1
  
  Pages: 80-89
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Oxytocin-induced elevation of ADP-ribosyl cyclase activity, cyclic ADP-ribose orCa(2+) concentrations is involved in autoregulation of oxytocin secretion in thehypothalamus and posterior pituitary in male mice.2010
- Author(s)
  Lopatina O, Liu HX, Amina S, Hashii M, Higashida H.
- Journal Title
  
  Neuropharmacology
  
  Volume: 58 Pages: 50-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] Intracellular calciuln elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15neuronal cells with or without exogenous expression of human oxytocinreceptors.2010
- Author(s)
  Amina S, Hashu M, Ma WJ, Yokoyama S, Higashida H, et al.
- Journal Title
  
  J.Neuroendocrinol.
  
  Volume: 22 Pages: 460-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] CD38/cADPR-SYSTEM: A NEW PLAYER FOR OXYTOCIN SECRETION AND REGULATION OF SOCIAL BEHAVIOUR2010
- Author(s)
  Salmina AB, Lopatina O, Ekimova MV, Mikhutkina SV, Higashida H.
- Journal Title
  
  J Neuroendocrinol 22
  
  Pages: 380-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Expression of a Rho Guanine Nucleotide Exchange Factor, Ect2, in the Developing Mouse Pituitary2010
- Author(s)
  Islam MS, Tsuji T, Higashida C, Takahashi M, Higashida H, Koizumi K.
- Journal Title
  
  J Neuroendocrinol 22
  
  Pages: 477-482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] CD38/cADPR-SYSTEM : A NEW PLAYER FOR OXYTOCIN SECRETION AND REGULATION OF SOCIAL BEHAVIOUR2010
- Author(s)
  Salmina AB, Lopatina O, Ekimova MV, Mikhutkina SV, Higashida H.
- Journal Title
  
  J Neuroendocrinol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] The two genetic variants of CD38 in subjects with autism spectrum disorder and controls2010
- Author(s)
  Munesue T., Koizumi K. (54名中10番目), Higashida H.
- Journal Title
  
  Neuroscience Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] オキシトシンとバソプレッシン-社会性認知行動と信頼の神経化学的基盤2010
- Author(s)
  東田陽博、小泉恵太、吉原亨、棟居俊夫
- Journal Title
  
  子どものこころと脳の発達
  
  Volume: 1 Pages: 180-189
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Intracellular calcium elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15 neuronal cells with or without exogenous expression of human oxytocin receptors2010
- Author(s)
  Amina,S.,Hashii,M.,Ma,W.J.,Yokoyama,S.,Lopatina,O.,Liu,H.X.,Islam,M.S.,Higashida,H
- Journal Title
  
  J. Neuroendocrinol
  
  Volume: 22 Issue: 5 Pages: 460-466
- DOI
  10.1111/j.1365-2826.2010.01978.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590202
[Journal Article] Two genetic variants of CD38 in subjects with autism spectrum disorder and controls2010
- Author(s)
  Munesue T, Yokoyama S, Nakamura K, Anitha A, Yamada K, Hayashi K, Asaka T, Liu HX, Jin D, Koizumi K, Islam MS, Huang JJ, Ma WJ, Kim UH, Kim SJ, ParkK, Kim D, Kikuchi M, Ono Y, Nakatani H, Suda S, Miyachi T, Hirai H, Salmina A, Pichugina YA, Soumarokov AA,Takei N, Mori N, Tsujii M, Sugiyama T, Yagi K, Yamagishi M, Sasaki T, Yamasue H, KatoN, Hashimoto R, Taniike M, Hayashi Y, Hamada J, Suzuki S, Ooi A, Noda M, Kamiyama Y, Kido MA, Lopatina O, Hashii M, Amina S, Malavasi F, Huang EJ, Zhang J, Shimizu N, Yoshikawa T, Matsushima A, Minabe Y, Higashida H.
- Journal Title
  
  Neurosci Res
  
  Volume: 67(2) Issue: 2 Pages: 181-91
- DOI
  10.1016/j.neures.2010.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791118, KAKENHI-PROJECT-22590202, KAKENHI-PROJECT-22590772
[Journal Article] Expression of a Rho Guanine Nucleotide Exchange Factor, Ect2, in the Developing Mouse Pituitary2010
- Author(s)
  Islam MS, Tsuji T, Higashida C, Takahashi M, Higashida H, Koizumi K.
- Journal Title
  
  J Neuroendocrinol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Intracellular Calcium Elevation Induced by Extracellular Application of Cyclic-ADP-Ribose or Oxytocin is Temperature-Sensitive in Rodent NG108-15 Neuronal Cells with or without Exogenous Expression of Human Oxytocin Receptors2010
- Author(s)
  Amina S, Hashii M, Ma WJ, Yokoyama S, Lopatina O, Liu HX, Islam MS, Higashida H.
- Journal Title
  
  J Neuroendocrinol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] The two genetic variants of CD38 in subjects with autism spectrum disorder and controls.2010
- Author(s)
  Munesue T, Koizumi K, Higashida H.
- Journal Title
  
  Neuroscience Research 67
  
  Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Oxytocin signal and social behaviour : comparison among adult and infant oxytocin, oxytocin receptor and CD38 gene knockout mice.2010
- Author(s)
  Higashida H., Munesue T., Salmina AB.
- Journal Title
  
  J Neuroendocrinol. 22
  
  Pages: 373-379
- NAID
  120002561624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Oxytocin-induced elevation of ADP-ribosyl cyclase activity, cyclic ADP-ribose or Ca(2+) concentrations is involved in autoregulation of oxytocin secretion in the hypothalamus and posterior pituitary in male mice2009
- Author(s)
  Lopatina O, Liu HX, Amina S, Hashii M, Higashida H.
- Journal Title
  
  Neuropharmacology 58
  
  Pages: 50-55
- NAID
  120001451026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] 自閉症分子マーカー探索-自閉症の遺伝子・分子生物・実験動物学的研究2009
- Author(s)
  東田陽博、堀家慎一、小泉惠太、吉原亨
- Journal Title
  
  医学のあゆみ 231
  
  Pages: 1072-1078
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] Long QT syndrome and associated gene mutation carriers in Japanese children : results from ECG screening examinations2009
- Author(s)
  Hayashi K, Fujino N, Uchiyama K, Ino H, Sakata K, Konno T, Masuta E, Funada A, Sakamoto Y, Tsubokawa T, Nakashima K, Liu L, Higashida H, Hiramaru Y, Shimizu M, Yamagishi M.
- Journal Title
  
  Clin Sci (Lond) 117
  
  Pages: 415-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Design and synthesis of 4", 6"-unsaturated cyclic ADP-carbocyclic-ribose, a Ca^<2+> -mobilizing agent selectively active in T cells.2008
- Author(s)
  Kudou, T., Murakami, T., Hashii, M., Higashida, H., ……Shuto, S., 他8名
- Journal Title
  
  Tetrahedron. 64
  
  Pages: 9754-9765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Genetic analyses of roundabout (ROBO) axon guidance receptors in autism2008
- Author(s)
  Anitha A, Nakamura K, Yamada K, Suda S, Thanseem I, Tsujii M, Iwayama Y, Hattori E, Toyota T, Miyachi T, Iwata Y, Suzuki K, Matsuzaki H, Kawai M, Sekine Y, Tsuchiya K, Sugihara G, Ouchi Y, Sugiyama T, Koizumi K, Higashida H, Takei N, Yoshikawa T, Mori N.
- Journal Title
  
  Am J Med Genet B Neuropsychiatr Genet 147B
  
  Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Design and synthesis of 4", 6"-unsaturated cyclic ADP-carbocyclic ribose as a Ca^<2+> -mobilizing agent.2008
- Author(s)
  Kudou, T., Weber, K., ……Hashii, M., Higashida, H., ……Shuto, S., 他4名
- Journal Title
  
  Tetrahedron Letters 49
  
  Pages: 3976-3979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Design and synthesis of 4",6"-unsaturated cyclic ADP-carbocyclic-ribose, a Ca^<2+>-mobilizing agent selectively active in T cells2008
- Author(s)
  Kudoh T, Hashii M, Higashida H, Shuto S et.al.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 9754-9765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19045011
[Journal Article] Genetic analyses of roundabout (ROBO) axon guidance receptors in autism.2008
- Author(s)
  Anitha A, Nakamura K, ……Koizumi K, Higashida H, ……Mori N., 他19名
- Journal Title
  
  Am J Med Genet B Neuropsychiatr Genet. 147B
  
  Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice2008
- Author(s)
  Liu HX, Lopatina O, Higashida C, Tsuji T, Kato I, Takasawa S, Okamoto H, Yokoyama S, Higashida H.
- Journal Title
  
  Neurosci Lett. 448
  
  Pages: 67-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Locomotor activity, ultrasonic vocalization and oxytocin levels in infant CD38 knockout mice.2008
- Author(s)
  Liu HX, Lopatina 0, ……Y okoyama S, Higashida H., 他5名
- Journal Title
  
  Neurosci Lett. 448
  
  Pages: 67-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Design and synthesis of 4", 6"-unsaturated cyclic ADP-carbocyclic rib ose as a Ca^<2+>-mobilizing agent2008
- Author(s)
  Kudoh T, Hashii M, Higashida H, Shuto S et.al.
- Journal Title
  
  Tetrahedron Lett 49
  
  Pages: 3976-3979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19045011
[Journal Article] Genetic analyses of roundabout (ROBO) axon guidance receptors in autism.2008
- Author(s)
  Anitha A, Koizumi K.Higashida H., Mori N.
- Journal Title
  
  Am J Med Genet B Neuropsychiatr Genet. 147B(7)
  
  Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500323
[Journal Article] CD38 is critical for social behavior by regulating oxytocin secretion2007
- Author(s)
  Jin, D., Liu, H.-X., Hirai, H., Torashima, T., Nagai, T., Lopatina, O., Schayder, N., Yamada, K., Noda, M., Seike, T., Fujita, K., Takasawa, S., Yokovama, S., Koizumi, K., Shiraishi, M., Tanaka, S., Hashii, M., Yoshihara, T., Higashida, K., Islam, Md., Yamada, N., Hayashi, K., Noguchi, N., Kato, I., Okamoto, H., Matsushima, A., Salmina, A., Munesue, T., Shimizu, N., Mochida, S., Asano, M., Higashida, H
- Journal Title
  
  Nature 446
  
  Pages: 41-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system2007
- Author(s)
  Higashida, H., et. al.
- Journal Title
  
  Neurochem.Int. 51
  
  Pages: 192-199
- NAID
  120001141007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] CD38 is critical for social behaviolour by regulating oxytocin secretion2007
- Author(s)
  Jin, D., LIU, HX., ……YokoYama, S., Koizumi, K, …Hashii, M., ……Munesue, T., ……Higashida, H. (他24名)
- Journal Title
  
  Nature 446
  
  Pages: 41-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] CD38 is critical for social behaviour by regulating oxytocin secretion2007
- Author(s)
  Jin D, Liu HX, Hirai H, Torashima T, Nagai T, Lopatina O, Shnayder NA, Yamada K, Noda M, Seike T, Fujita K, Takasawa S, Yokoyama S, Koizumi K, Shiraishi Y, Tanaka S, Hashii M, Yoshihara T, Higashida K, Islam MS, Yamada N, Hayashi K, Noguchi N, Kato I, OkaJin D, Liu HX, Hirai H, Torashima T, Nagai T, Lopatina O, Shnayder NA, Yamada K, Noda M
- Journal Title
  
  Nature 446
  
  Pages: 41-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Overexpression of constitutively active form of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced M(KCNQ) -current inhibition in rodent NG108-15 neuroblastoma cells2007
- Author(s)
  Higashida, H., Bowden, S., E., H., Yokovama. S., Egorova, A., Hashii, M., Hoshi, N., Zhang, J.-S., Knijnik, R., Noda, M., Zhong, Z.-G., Takeda, H., Akita, T., Kuba, K., Yamagishi, S., Shimizu, N., Takasawa, S., Okamoto, H., Robbins, J
- Journal Title
  
  Neurosci. Res 57
  
  Pages: 339-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Identification of calreticulin as a marker for phagocytosis of apoptotic cells in Drosophila.2007
- Author(s)
  Kuraishi T, Manaka J, Kono M, Ishii H, Yamamoto N, Koizumi K, Shiratsuchi A, Lee BL, Higashida H, Nakanishi Y
- Journal Title
  
  Exp Cell Res. 313
  
  Pages: 500-510
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system.2007
- Author(s)
  Higashida H, Salmina AB, Olovyannikova RY, Hashii M, Yokoyama S, Koizumi K, Jin D, Liu HX, Lopatina O, Amina S, Islam MS, Huang JJ, Noda M.
- Journal Title
  
  Neurochem Int. 51
  
  Pages: 192-199
- NAID
  120001141007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Overexpression of constitutively active form of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced M(KCNQ)-current inhibition in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida, H. et al.
- Journal Title
  
  Neurosci. Res. 57
  
  Pages: 339-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Identification of calreticulin as a marker for phagocytosis of apoptoti cells in Drosophila.2007
- Author(s)
  Kuraishi T, ……Koiaumi K, ……Higashida H,. (他6名)
- Journal Title
  
  Exp Cell Res. 313
  
  Pages: 500-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] [Biological basis for social recognition: CD38 controls oxytocin secretion]2007
- Author(s)
  Higashida H.
- Journal Title
  
  Tanpakushitsu Kakusan Koso. Review. Japanese. 52
  
  Pages: 1832-1839
- NAID
  40015676748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Overexpression of constitutively active form of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced M(KCNQ)-current inhibition in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida, H., et al.
- Journal Title
  
  Neurosci. Res. 57
  
  Pages: 339-346
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system2007
- Author(s)
  Higashida, H., Salmina, A., B., Olovyannikova, R., Hashii, M., Yokovama, S., Koizumi, K., Jin, D., Liu, H., X., Lopatina, O., Amita, S., Islam, S. Md., Jun, H., J., Noda, M
- Journal Title
  
  Neurochem. Int 51
  
  Pages: 192-199
- NAID
  120001141007
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Overexpression of constitutively active form of CD38/ADP-ribosyl cyclase enhances acetylcholine-induced M(KCNQ)-current inhibition in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida, H., et. al.
- Journal Title
  
  Neurosci. Res. 57
  
  Pages: 339-346
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca (2+) signalling in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida H, Yokoyama S, Salmina A, Hashii M, Hoshi N, Jin D(他13名), Robbins J
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- NAID
  10024413034
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system.2007
- Author(s)
  Higashida H, Salmina AB, Hashii M, et. al.
- Journal Title
  
  Neurochem. Int. 51
  
  Pages: 192-199
- NAID
  120001141007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19045011
[Journal Article] Cychc ADP-ribose as a universal calcium signal molecule in tthe nervous system.2007
- Author(s)
  Higashida H, ……Hashii M, Yokoyamas, Koizumi K, (他9名)
- Journal Title
  
  Neurochem Int. 51
  
  Pages: 192-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells:Intracellular concentration decrease in NAD and increase in cyclic ADP-ribose.2007
- Author(s)
  Higashida, H., et. al.
- Journal Title
  
  FEBS Letters 446
  
  Pages: 41-45
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca(2+) signalling in rodent NG108-15 neuroblastoma cells2007
- Author(s)
  Higashida H, Bowden SE, Yokoyama S, Salmina A, Hashii M, Hoshi N, Zhang JS, Knijnik R, Noda M, Zhong ZG, Jin D, Higashida K, Takeda H, Akita T, Kuba K, Yamagishi S, Shimizu N, Takasawa S, Okamoto H, Robbins J.
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- NAID
  10024413034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Oxytocin released from mouse hypothalamus and nerve endings by extracellular application of beta-NAD^+ and cyclic ADP ribose2007
- Author(s)
  Jin, D., Liu, X., X., Lopatina, O., Hashii, M., Yokovama, S., Koizumi, K., Amina, S., Shuto, S., Shiraishi, Y, Tanaka, S., Higashida, H
- Journal Title
  
  Nat. Protocols. (Protocols Network) DOI : 10.1038/nprot.2007
  
  Pages: 214-214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Oxytocin released from mouse hypothalamus and nerve endings by extracellular applicaion of beta-NAD+ and cyclic ADP-ribose.2007
- Author(s)
  Jin D, Hashii M, Higashida H, et. al.
- Journal Title
  
  Nature Protocols 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19045011
[Journal Article] RNA interference screen to identify genes required for Drosophila embryonic nervous system development.2007
- Author(s)
  Koizumi K, Higashida H, Yoo S, Islam MS, Ivanov AI, Guo V, Pozzi P, Yu SH, Rovescalli AC, Tang D, Nirenberg M
- Journal Title
  
  Proc Natl Acad Sci U S A 104
  
  Pages: 5626-5631
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] RNA interference screen to identify genes required for Drosophia embryonic nervouS system developmnent.2007
- Author(s)
  Koizumi K, Higashida, ……Nirenberg M. (他8名)
- Journal Title
  
  Proc Natl Acad Sci U S A 104
  
  Pages: 5626-5631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] CD38 is critical for social behaviour by regulating oxytocin secretion.2007
- Author(s)
  Jin D, Liu HX, Hirai H, Yokoyama S, Hashii M, A, Salmina A, Asano M(他24名), Higashida H
- Journal Title
  
  Nature. 446
  
  Pages: 41-45
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Cyclic ADP-ribose as a universal calcium signal molecule in the nervous system.2007
- Author(s)
  Higashida, H., et. al.
- Journal Title
  
  Neurochem. Int. 51
  
  Pages: 192-199
- NAID
  120001141007
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Identification of calreticulin as a marker for phagocytosis of apoptotic cells in Drosophila2007
- Author(s)
  Kuraishi T, Manaka J, Kono M, Ishii H, Yamamoto N, Koizumi K, Shiratsuchi A, Lee BL, Higashida H, Nakanishi Y.
- Journal Title
  
  Exp Cell Res. 313
  
  Pages: 500-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca(2+)signanillg in rodent NG108-15 neuroblastoma cells.2007
- Author(s)
  Higashida H, ……Yokoyama S, ……Hashii M, (他17名)
- Journal Title
  
  Neurosci Res. 57
  
  Pages: 339-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] RNA interference screen to identify genes required for Drosophila embryonic nervous system development2007
- Author(s)
  Koizumi K, Higashida H, Yoo S, Islam MS, Ivanov AI, Guo V, Pozzi P, Yu SH, Rovescalli AC, Tang D, Nirenberg M.
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 5626-5631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells : intracellular concentration decrease in NAD and increase in cyclic ADP-ribose2006
- Author(s)
  Higashida, H., Salmina, A., Hashii, M., Yokovama, S., Zhang, J.-S., Noda, M., Zhong, Z.-H., Jin, D
- Journal Title
  
  FEBS Lett 580
  
  Pages: 4857-6850
- NAID
  120000809376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] ADP-Ribosyl Cyclase as a Therapeutic Target for Central Nervous System Diseases.2006
- Author(s)
  Salmina A., Olvyannikova R., Noda M., Higashida H.
- Journal Title
  
  Central Nervous System Agents in Medicinal Chemistry. 6
  
  Pages: 193-210
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells : intracellular concentrati on decrease in NAD and increase in cyclic ADP-ribose.2006
- Author(s)
  Higashida H., Salmina A., Hashii M., Yokoyama S., Zhang J-S., Noda M., Zhong Z G., Jin D.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 4857-4860
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells : intracellular concentration decrease in NAD and increase in cyclic ADP-ribose.2006
- Author(s)
  Higashida, H. et al.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 4857-6850
- NAID
  120000809376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells : intracellular concentration decrease in NAD and increase in cyclic ADP-ribose.2006
- Author(s)
  Higashida, H., et al.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 4857-6850
- NAID
  120000809376
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells : Intracellular concentration decrease in NAD and increase in cyclic ADP-ribose.2006
- Author(s)
  Haruhiro Higashida, et al.
- Journal Title
  
  FEBS Letters 580
  
  Pages: 4857-4860
- NAID
  120000809376
- Data Source
  KAKENHI-PROJECT-18613003
[Journal Article] Acetylcholine stimulates cyclic ADP-ribose formation via M1 muscarinic receptors in rat superior cervical ganglion.2005
- Author(s)
  Zhang JS, Jin D, Higashida H.
- Journal Title
  
  Biochem Biophys Res Commun. 335
  
  Pages: 920-924
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic recep tor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida H, Hoshi N, Zhang JS, Yokoyama S, Hashii M, Jin D, Noda M, Robbins J.
- Journal Title
  
  Neurosci Res. 51
  
  Pages: 231-234
- NAID
  10015451122
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida, H., et al.
- Journal Title
  
  Neurosci. Res. 53
  
  Pages: 231-234
- NAID
  10015451122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida H, Hoshi N, Zhang JS, Yokoyama S, Hashii M, Jin D, Noda M, Robbins J.
- Journal Title
  
  Neurosci Res. 51
  
  Pages: 231-234
- NAID
  10015451122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida H, Hoshi N, Zhang JS, Yokoyama S, Hashii M, Jin D, Noda M, Robbins J.
- Journal Title
  
  Neurosci Res. 51
  
  Pages: 231-234
- NAID
  10015451122
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure-activity relationship of the N1-ribose moiety.2005
- Author(s)
  Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S.
- Journal Title
  
  J Am Chem Soc. 127
  
  Pages: 8846-8855
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Acetylcholine stimulates cyclic ADP-ribose formation via M1 muscarinic receptors in rat superior cervical ganglion.2005
- Author(s)
  Zhang JS, Jin D, Higashida H.
- Journal Title
  
  Biochem Biophys Res Commun. 335
  
  Pages: 920-924
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety.2005
- Author(s)
  Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S.
- Journal Title
  
  Am Chem Soc. 127
  
  Pages: 8846-8855
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Cyclin-dependent kinase 5 activators p35 and p39 facilitate formation of functional synapses.2005
- Author(s)
  Johansson JU, Lilja L, Chen XL, Higashida H, Meister B, Noda M, Zhong ZG, Yokoyama S, Berggren PO, Bark C.
- Journal Title
  
  Brain Res Mol Brain Res. 138
  
  Pages: 215-227
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Induction of interleukin-6 in dorsal root ganglion neurons after gradual elongation of rat sciatic nerve.2005
- Author(s)
  Osamura N, Ikeda K, Ito T, Higashida H, Tomita K, Yokoyama S.
- Journal Title
  
  Exp Neurol. 195
  
  Pages: 61-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida, H.
- Journal Title
  
  Νευροσχι.Ρεσ. 53
  
  Pages: 231-234
- NAID
  10015451122
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Cyclin-dependent kinase 5 activators p35 and p39 facilitate formation of functional synapses.2005
- Author(s)
  Johansson JU, Lilja L, Chen XL, Higashida H, Meister B, Noda M, Zhong ZG, Yokoyama S, Berggren PO, Bark C.
- Journal Title
  
  Brain Res Mol Brain Res. 138
  
  Pages: 215-227
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Induction of interleukin-6 in dorsal root ganglion neurons after gradual elongation of rat sciatic nerve.2005
- Author(s)
  Osamura N, Ikeda K, Ito T, Higashida H, Tomita K, Yokoyama S.
- Journal Title
  
  Exp Neurol. 195
  
  Pages: 61-70
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells.2005
- Author(s)
  Hashii M, Shuto S, Fukuoka M, Kudoh T, Matsuda A, Higashida H.
- Journal Title
  
  J Neurochem. 94
  
  Pages: 316-323
- NAID
  120000809381
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Acetylcholine stimulates cyclic ADP-ribose formation via M1 muscarinic receptors in rat superior cervical ganglion.2005
- Author(s)
  Zhang JS, Jin D, Higashida H.
- Journal Title
  
  Biochem Biophys Res Commun. 335
  
  Pages: 920-924
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure-activity relationship of the N1-ribose moiety.2005
- Author(s)
  Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S.
- Journal Title
  
  J Am Chem Soc. 127
  
  Pages: 8846-8855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells.2005
- Author(s)
  Hashii M, Shuto S, Fukuoka M, Kudoh T, Matsuda A, Higashida H.
- Journal Title
  
  J Neurochem. 94
  
  Pages: 316-323
- NAID
  120000809381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Acetylcholine stimulates cyclic ADP-ribose formation via M1 muscarinic receptors in rat superior cervical ganglion.2005
- Author(s)
  Zhang JS, Jin D, Higashida H.
- Journal Title
  
  Biochem Biophys Res Commun 335
  
  Pages: 920-924
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida, H. et al.
- Journal Title
  
  Neurosci.Res. 53
  
  Pages: 231-234
- NAID
  10015451122
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure-activity relationship of the N1-ribose moiety.2005
- Author(s)
  Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S.
- Journal Title
  
  J Am Chem Soc. 127
  
  Pages: 8846-8855
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells.2005
- Author(s)
  Hashii M, Shuto S, Fukuoka M, Kudoh T, Matsuda A, Higashida H.
- Journal Title
  
  Neurochem. 94
  
  Pages: 316-323
- NAID
  120000809381
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety.2005
- Author(s)
  Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S.
- Journal Title
  
  J Am Chem Soc. 127
  
  Pages: 8846-8855
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in N G108-15 neuronal cells.2005
- Author(s)
  Hashii M, Shuto S, Fukuoka M, Kudoh T, Matsuda A, Higashida H.
- Journal Title
  
  J Neurochem. 94
  
  Pages: 316-323
- NAID
  120000809381
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Induction of interleukin-6 in dorsal root ganglion neurons after gradual elongation of rat sciatic nerve.2005
- Author(s)
  Osamura N, Ikeda K, Ito T, Higashida H, Tomita K, Yokoyama S.
- Journal Title
  
  Exp Neurol. 195
  
  Pages: 61-70
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Acetylcholine stimulates cyclic ADP-ribose formation via Ml muscarinic receptors in rat superior cervical ganglion.2005
- Author(s)
  Zhang JS, Jin D, Higashida H.
- Journal Title
  
  Biochem Biophys Res Commun. 335
  
  Pages: 920-924
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ notassium channels.2005
- Author(s)
  Higashida, H. et al.
- Journal Title
  
  Neurosci. Res. 53
  
  Pages: 231-234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Cyclin-dependent kinase 5 activators p35 and p39 facilitate formation of functional synapses.2005
- Author(s)
  Johansson JU, Lilia L, Chen XL, Higashida H, Meister B, Noda M, Zhong ZG, Yokoyama S, Berggren PO, Bark C.
- Journal Title
  
  Brain Res Mol Brain Res. 138
  
  Pages: 215-227
- Data Source
  KAKENHI-PROJECT-17024020
[Journal Article] Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels.2005
- Author(s)
  Higashida H, Hoshi N, Zhang JS, Yokoyam S, Hashii M, Jin D, Noda M, Robbins J.
- Journal Title
  
  Neurosci Res. 51
  
  Pages: 231-234
- NAID
  10015451122
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages.2004
- Author(s)
  Manaka J, Kuraishi T, Shiratsuchi A, Nakai Y, Higashida H, Henson P, Nakanishi Y
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 48466-48476
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Multiple signal transduction pathways mediated by 5-HT receptors.2004
- Author(s)
  Noda M, Higashida H, Aoki S, Wada K.
- Journal Title
  
  Mol Neurobiol 29
  
  Pages: 31-39
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Multiple signal transduction pathways mediated by 5-HT receptors.2004
- Author(s)
  Noda M, Higashida H, Aoki S, Wada K.
- Journal Title
  
  Mol Neurobiol 29
  
  Pages: 31-39
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG.2004
- Author(s)
  Hayashi K, Shimizu M, Ino H, Yamaguchi M, Terai H, Hoshi N, Higashida H, Terasima N, Uno Y, Kanaya H, Mabuchi H.
- Journal Title
  
  Clinical Science 107
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages.2004
- Author(s)
  Manaka J, Kuraishi T, Shiratsuchi A, Nakai Y, Higashida H, Henson P, Nakanishi Y
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 48466-48476
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the terminus of HERG.2004
- Author(s)
  Hayashi, K., Hoshi N., Higashida H., et al.
- Journal Title
  
  Clin Sci(Lond) 107
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-16500261
[Journal Article] Genes required for Drosophila nervous system development identified by RNA interference.2004
- Author(s)
  Ivanov AI, Rovescalli AC, Pozzi P, Yoo S, Mozer B, Li HP, Yu SH, Higashida H, Guo V, Spencer M, Nirenberg M.
- Journal Title
  
  Proc Natl Acad Sci U S A. 101
  
  Pages: 16216-16221
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG.2004
- Author(s)
  Hayashi K, Shimizu M, Ino H, Yamaguchi M, Terai H, Hoshi N, Higashida H, Terashima N, Uno Y, Kanaya H, Mabuchi H.
- Journal Title
  
  Clinical Science 107
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-16650068
[Journal Article] Genes required for Drosophila nervous system development identified by RNA interference.2004
- Author(s)
  Ivanov AI, Rovescalli AC, Pozzi P, Yoo S, Mozer B, Li HP, Yu SH, Higashida H, Guo V, Spencer M, Nirenberg M.
- Journal Title
  
  Proc Natl Acad Sci U S A. 101
  
  Pages: 16216-16221
- Data Source
  KAKENHI-PROJECT-15300124
[Journal Article] イオンチャネルと結合するアンカリング蛋白AKAPの役割2004
- Author(s)
  東田陽博他
- Journal Title
  
  生体の科学 55
  
  Pages: 129-132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical ganglion and NG108-15 cells.2003
- Author(s)
  Higashida, H., et al.
- Journal Title
  
  J. Neurochem. 85
  
  Pages: 1148-1158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical ganglion and NG108-15 cells.2003
- Author(s)
  Higashida, H. et al.
- Journal Title
  
  J. Neurochem. 85
  
  Pages: 1148-1158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500255
[Journal Article] Decreased ADP-ribosyl cyclase activity in peripheral blood mononuclear cells from diabetic patients with nephropathy
- Author(s)
  Ohtsuji M, Yagi K, Shintaku-Kubota M, Kojima-Koba Y, Ito N, Sugihara M, Yamaaki N, Chujo D, Nohara A, Takeda Y, Kobayashi J, Yamagishi M, Higashida H.
- Journal Title
  
  Exp Diabetes Res
- NAID
  120001491366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200030
[Journal Article] Social memory, mental care and oxytocin secretion, but not vasopressin release, require CD38 in mice
- Author(s)
  Higashida, H., Jin, D., Liu, H.-X., Lopatina, O., Yokovama, S., Koizumi, K., Hashii, M., Islam, S., Md., Hayashi, K., Munesue, T
- Journal Title
  
  In : Neurobiology of the Parental Mind, Academic Press (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Patent] 新規オキシトシン誘導体およびそれを含む医薬組成物2014
- Inventor(s)
  周東　智、水野　彰、東田陽博
- Industrial Property Rights Holder
  周東　智、水野　彰、東田陽博
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-139048
- Filing Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-24390023
[Patent] CD38による自閉症の診断と治療2007
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Filing Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-19200030
[Patent] CD38による自閉症の診断と治療2007
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Filing Date
  2007-11-15
- Overseas
- Data Source
  KAKENHI-PROJECT-19200030
[Patent] CD38による自閉症の診断と治療2006
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Industrial Property Number
  2006-339054
- Filing Date
  2006-12-15
- Data Source
  KAKENHI-PROJECT-16650068
[Patent] パーキンソン病の治療のための医薬2005
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Industrial Property Number
  2005-189518
- Filing Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-17024020
[Patent] パーキンソン病の治療のための医薬2005
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Industrial Property Number
  2005-189518
- Filing Date
  2005-07-15
- Data Source
  KAKENHI-PROJECT-16650068
[Patent] パーキンソン病の治療のための医薬2005
- Inventor(s)
  東田陽博
- Industrial Property Rights Holder
  金沢大学TLO
- Industrial Property Number
  2005-189518
- Filing Date
  2005-07-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300124
[Presentation] 自閉症, 精神遅滞などの発達障害に関わることが期待される新規遺伝子2012
- Author(s)
  小泉惠太, 東田陽博, 中島日出夫
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡, マリンメッッセ福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23500427
[Presentation] 自閉症、精神遅滞などの発達障害に関わることが期待される新規遺伝子2012
- Author(s)
  小泉惠太、東田陽博、中島日出夫
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッッセ福岡、福岡
- Data Source
  KAKENHI-PROJECT-23500427
[Presentation] 合成サイクリックADPリボースアナログ構造の違いによる神経細胞内Ca2+動員効果の比較2011
- Author(s)
  橋井美奈子、周東智、東田陽博
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(石川県)
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22590202
[Presentation] Fly/Mouse studies identify genes that have important role to cause human developmental disorders such as mental retardation and autism.2011
- Author(s)
  小泉惠太、中島日出夫、東田陽博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23500427
[Presentation] Fly/mouse studies identify genes that have important role to cause human developmental disorders including mental retardation and autism2011
- Author(s)
  Koizumi K, Nakajima H, Higashida H
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23500427
[Presentation] 合成サイクリックADPリボースアナログ構造の違いによる神経細胞内Ca^<2+>動員効果の比較2011
- Author(s)
  橋井美奈子, 周東智, 東田陽博
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(石川県加賀市)
- Data Source
  KAKENHI-PROJECT-22590202
[Presentation] Fly/Mouse analysis of genes that cause autism and human developmental disorders.2010
- Author(s)
  Koizumi K, Nkajima H, Higashida H
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] マウス脳内のEct2の発現解析2010
- Author(s)
  吉田康真,,,小泉恵太(7名中5番目),,,東田陽博
- Organizer
  分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] マウス脳内のEct2の発現解析2010
- Author(s)
  吉田康真, 小泉惠太, 東田陽博
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Improved social communication after nasal oxytocin administration in a Japanese autistic patient with severe mental retardation.2010
- Author(s)
  Higashida, H., et al.
- Organizer
  A Brain Research meeting : The Emerging Neuroscienceof Autism Spectrum Disorders : Etiologic Insights ; Treatment Opportunities
- Place of Presentation
  Westin Hotel, San Diego, CA, U.S.A.
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21600002
[Presentation] サイクリックADPリボース合成酵素CD38の細胞移動に対する役割2010
- Author(s)
  橋井美奈子、サラワトアミナ、オリガロパチナ、東田陽博
- Organizer
  第53回日本神経化学会大会
- Place of Presentation
  神戸コンベンションセンター (兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590202
[Presentation] サイクリックADPリボース合成酵素CD38の細胞移動に対する役割2010
- Author(s)
  橋井美奈子、サラワトアミナ、オリガロパチナ、東田陽博
- Organizer
  第53回日本神経化学会大会
- Place of Presentation
  神戸コンベンションセンター(神戸、兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590202
[Presentation] Fly/Mouse analysis of genes that cause autism and human developmental disorders.2010
- Author(s)
  Koizumi K, Nkajima H, Higashida H
- Organizer
  分子生物学会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] CD38は視床下部のオキシトシン分泌を介して、社会認識行動に関与する2009
- Author(s)
  東田陽博
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] 仔どもから大人までのマウスの社会認識行動と血清オキシトシン濃度は視床下部のCD38/ADP-リボース環状化酵素により制御される2009
- Author(s)
  東田陽博
- Organizer
  第32回日本神経科学会大会
- Place of Presentation
  名古屋国際会議場 (愛知)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] Genetic studies of human developmental disorders using Drosophila/mouse as model animals.2009
- Author(s)
  小泉惠太, 東田陽博
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Expression of Gpnmb, a tumor metastasis-associated glycoprotein, in the rat central nervous system2009
- Author(s)
  Huang, J.-J., Ma, W.-J., Higashida, H., and Yokoyama, S
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂交流ホール石川県金沢市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21600002
[Presentation] Genetic studies of human developmental disorders using Drosophila/mouse as model animals2009
- Author(s)
  Koizumi, K., Higashida H.
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Expression of Gpnmb, a tumor metastasis-associated glycoprotein, in the rat central nervous system2009
- Author(s)
  Huang, J.-J., Ma, W.-J., Higashida, H., and Yokoyama, S
- Organizer
  金沢大学創基150周年記念「講演会・シンポジウム」シリーズ第2回「社会認識」学際脳科学シンポジウム
- Place of Presentation
  金沢大学医学部記念館石川県金沢市
- Data Source
  KAKENHI-PROJECT-21600002
[Presentation] Oxytocin levels in adult and infant CD38 knockout mice critically relate to social behavior.2009
- Author(s)
  東田陽博, et al.
- Organizer
  19th Neuropharmacology Conference
- Place of Presentation
  Hyatt Regacy McCormick Place(Chicago, U.S.A.)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21600002
[Presentation] CD38は視床下部のオキシトシン分泌を介して、社会認識行動に関与する2009
- Author(s)
  東田陽博
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] 仔どもから大人までのマウスの社会認識行動と血清オキシトシン濃度は視床下部のCD38/ADP-リボース環状化酵素により制御される2009
- Author(s)
  東田陽博
- Organizer
  第32回日本神経科学会大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] CD157と脳機能2009
- Author(s)
  東田陽博, 他
- Organizer
  第56回中部日本生理学会
- Place of Presentation
  石川県立音楽堂交流ホール(石川県)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21600002
[Presentation] CD38:オキシトシン遊離調節による社会認識行動、社会認識、オキシトシンとCD382008
- Author(s)
  東田陽博
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山国際会議場(富山県)
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] CD38 and social brain : Autistic behavior regulated by oxytocin release in a cyclic ADP-ribose-depende nt fashion2008
- Author(s)
  東田陽博
- Organizer
  NAD2008
- Place of Presentation
  Elsa-Brandstrom-Haus, Hamburg-ablanken ese, (ドイツ)
- Year and Date
  2008-09-14
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] Social and Autistic Beha vior Regulated by Oxytocin Release in a CD38, Cyclic ADP-ribose and Calcium-De pendent Fashion2008
- Author(s)
  東田陽博
- Organizer
  Korean Society of Medi cal Biochemistry and Molecuar Biology
- Place of Presentation
  ホテルソウル教育文化会館(韓国)
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] CD38 : オキシトシン遊離調節による社会認識行動社会認識、オキシトシンとCD382008
- Author(s)
  東田陽博
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山国際会議場
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] ショウジョウバエを用いた発達障害原因遺伝子の探索とマウス/ショウジョウバエをモデルとした分子機能解析2008
- Author(s)
  小泉恵太, Saharul M. I. 東田陽博
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] PRC1複合体のマウス胚cortexでの発現解析2008
- Author(s)
  Saharul M. I., 小泉惠太, 吉原亨, 浅野雅秀, 東田陽博
- Organizer
  第51回日本神経化学会(富山)大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Social and Autistic Behavior Regulated by Oxytocin Release in a CD38, Cyclic ADP-ribose and Calcium-Dependent Fashion2008
- Author(s)
  東田陽博
- Organizer
  Korean Society of Medical Biochemistry and Molecuar Biology
- Place of Presentation
  ホテルソウル教育文化会館(韓国)
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] CD38 and social brain : Autistic behavior regulated by oxytocin release in a cyclic ADP-ribose-dependent fashion2008
- Author(s)
  東田陽博
- Organizer
  NAD2008
- Place of Presentation
  Elsa-Brandstrom-Haus, Hamburg-ablankenese, Germany
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] PRC1 複合体のマウス胚cortexでの発現解析2008
- Author(s)
  Saharul M.I,,小泉惠太, 吉原亨, 浅野雅秀, 東田陽博
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Social recognition, Oxyto cin, and CD382008
- Author(s)
  東田陽博
- Organizer
  World Congress on Psychia tric Genetics
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2008-10-13
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] Social recognition, Oxytocin, and CD382008
- Author(s)
  東田陽博
- Organizer
  World Congress on Psychiatric Genetics
- Place of Presentation
  大阪国際会議場
- Year and Date
  2008-10-13
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] ショウジョウバエを用いた発達障害原因遺伝子の探索とマウス/ショウジョウバエをモデルとした分子機能解析2008
- Author(s)
  小泉惠太, Saharul.M.I.東田陽博
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20500323
[Presentation] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+elevation by synthetic carbocyclic analogues ofcyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells2007
- Author(s)
  橋井美奈子、周東智、東田陽博
- Organizer
  Neuro2007
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19045011
[Presentation] Trial of social behavior tests in ordinal house mice2007
- Author(s)
  Jin, D., Liu, H.-X., Hashii, M., Yokovama, S., Koizumi, K., Lopatina, O., Islam, S., Md., Higashida, H
- Organizer
  The 49th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Presentation] CD38-Dependent Oxytocin Release on Socialand Parental Behavior.2007
- Author(s)
  東田陽博
- Organizer
  PARENTAL BRAIN CONFERENCE
- Place of Presentation
  Back Bay Hilton Hotel-Boston, Massachusetts
- Year and Date
  2007-06-08
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] ADP-ribosyl cyclase activity and oxytocin levels in mouse maternal behavior2007
- Author(s)
  Lopatina, O., Koizumi, K., Schnayder, N., Liu, H.-X., Jin, D., Yokovama, S., Hashii, M., Islam, S., Md., Amina, S., Higashida, H
- Organizer
  The 50th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-09-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Presentation] CD38-Dependent Oxytocin Release on Social and Parental Behavior2007
- Author(s)
  東田陽博
- Organizer
  PARENTAL BRAIN CONFERENCE
- Place of Presentation
  Back Bay Hilton Hotel-Boston, Massachusetts(アメリカ)
- Year and Date
  2007-06-08
- Data Source
  KAKENHI-PROJECT-19200030
[Presentation] Upregulation of collagen type VI in the axotomized rat sciatic nerve2007
- Author(s)
  Yokovama, S., Hinoki, S., Ikeda K., Tomita, K., Higashida, H
- Organizer
  The 38th Annual Meeting of Scociety for Neuroscience
- Place of Presentation
  San Diego, CA, U.S.A
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003
[Presentation] Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+elevation by synthetic carbocyclic analogues ofcyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells2007
- Author(s)
  Hashii M., Shuto S, Higashida H
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19045011
[Presentation] Induction of peripheral myelin protein 22 (PMP22) by interleukin-6 (IL-6) in cultured rat Schwann cells2006
- Author(s)
  Ito, T., Ikeda, K., Tomita, K., Higashida, H., Yokovama, S
- Organizer
  The 21th Academic Meeting of the Japanese Orthopaedic Association
- Place of Presentation
  Nagasaki, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613003

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higashida haruhiro 東田 陽博

HIGASHIDA Haruhiro 東田 陽博

東田 陽博 ヒガシダ ヒロハル

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higashida haruhiro 東田陽博

HIGASHIDA Haruhiro 東田陽博

東田陽博ヒガシダヒロハル