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Nagata Kazuhiro  永田 和宏

ORCIDConnect your ORCID iD *help
… Alternative Names

NAGATA Kazuhiro  永田 和宏

永田 和広  ナガタ カズヒロ

永田 和弘  ナガタ カズヒロ

長田 和宏  ナガタ カズヒロ

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Researcher Number 50127114
Other IDs
External Links
Affiliation (Current) 2025: 株式会社生命誌研究館, その他部局等, 館長
Affiliation (based on the past Project Information) *help 2020 – 2022: 株式会社生命誌研究館, その他部局等, 館長・顧問
2018 – 2019: 京都産業大学, 生命科学部, 教授
2017: 京都産業大学, 総合生命科学部 生命システム学科, 客員教授
2010 – 2017: 京都産業大学, 総合生命科学部, 教授
2011: 京都大学, 再生医学研究所, 教授 … More
2010: 京都大学, 総合生命科学部, 教授
1998 – 2010: 京都大学, 再生医科学研究所, 教授
2007: 京大, 再生医科学研究所, 教授
2007: 京都大学, 再生医科研究所, 教授
2005: Kyoto University, Institute for Frontier medical Science, Professor, 再生医学研究所, 教授
2001: 京都大学, 医学研究科, 教授
1988 – 1997: 京都大学, 胸部疾患研究所, 教授
1994: 京都大学, 胸部疾患研究科, 教授
1990: 京都大学, 胸部研, 教授
1990: 京都大学胸部疾患研究所, 教授
1986 – 1988: 京都大学, 結核胸部疾患研究所, 教授
1986: 京大, 結核胸部疾患研究所, 講師 Less
Review Section/Research Field
Principal Investigator
Cell biology / Biological Sciences / Cell biology / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Experimental pathology / Structural biochemistry
Except Principal Investigator
Biological Sciences / 広領域 / 物質生物化学 / Plastic surgery … More / Cerebral neurosurgery / Neurochemistry/Neuropharmacology / Surgical dentistry / Cerebral neurosurgery / Cell biology / Orthopaedic surgery / Cell biology / Hygiene / Digestive surgery / Thoracic surgery / 代謝生物化学 Less
Keywords
Principal Investigator
分子シャペロン / ストレス蛋白質 / HSP47 / コラーゲン / 熱ショック蛋白質 / EDEM / 小胞体 / 品質管理 / Molecular Chaperone / 小胞体関連分解 … More / プロコラーゲン / 温熱療法 / ER associated degradation / レドックス / フォールディング / Quality control / collagen / molecular chaperone / stress protein / 細胞内輸送 / heat shock proteins / stress proteins / 細胞機能制御 / 熱ショック転写因子 / ストレス応答 / 細胞分化 / 温熱耐性 / 熱耐性 / 小砲体 / 過酸化水素 / Receptor / Collagen / レセプター / 分子シヤペロン / 小胞体関連分野 / ER mannosidase / Quality control of proteins / 小胞体マンノシダーゼI / prion / transport / chaperonin / quality control / protein folding / Quality Control / プリオン / 蛋白質輸送 / シャペロニン / molecular chapreone / procollagen / promoter analysis / vimentin / intermediate filament / differentiation / leukemic cells / プロモーター解析 / ビメンチン / 中間径フィラメント / 白血病細胞 / stress response / chaperones / molecular / 核輸送 / HSP70 / モルテングロビュール / Heat shock transcription factor / Stress protein / トランスフォーメーション / 熱ショック蛋白質(ヒートショックプロテイン) / hsp47 / プロテオステイシス / レドックス恒常性 / カルシウム恒常性 / ERdj5 / ジスルフィド結合 / 小胞体品質管理 / レドックス制御 / 基底膜 / 結晶解析 / ノックアウトマウス / semi-permeabilized cell / Quality contorol / 転写制御 / HSP65 / HSP40 / サイトカイン / ビメンチン遺伝子 / マウス白血病細胞 / フラボノイド / コラ-ゲン / がん細胞 … More
Except Principal Investigator
分子シャペロン / ストレス蛋白質 / 細胞接着 / 細胞骨格 / アクチン / MMP / フィブロネクチン / ストレス応答 / molecular chaperone / 熱ショック蛋白質 / プロテオグリカン / インテグリン / 細胞外マトリックス / チューブリン / フォールディング / TIMP / 脳動脈瘤 / ERAD / UPR / 品質管理 / タンパク質 / コラーゲン / 蛋白質のフォールディング / ビメンチン / チロシンリン酸化 / TNF-α / IL-1β / 動物モデル / iNOS / 小胞体 / ミトコンドリア / タンパク質分泌 / heat shock protein / stress protein / シャペロン / stress response / Fibronectin / テネイシン / ビトロネクチン / 白血病細胞の分化 / リン酸化 / 創傷治癒 / ケロイド / アミロイド / レセプター / ATP / 構造解析 / SOS応答 / 酸化ストレス / 熱ショック応答 / 中間フィラメント / 微小管 / がん細胞の分化 / 熱ショックタンパク質 / 老化制御因子 / ホメオスタシス / アクチンリモデリング / Rictor / mTORC2 / インスリンシグナル / アセチル化 / 老化 / アセチル化修飾 / Akt / mTOR / オートファジー / Mdm20 / HDAC6 / 神経老化 / Glycoprotein / Cell spreading / Cell attachment / 血液 / 細胞間マトリックス / 細胞表面 / 接着性糖タンパク質 / 血漿タンパク質 / 糖タンパク質 / 細胞伸展 / Reprogramming / Stem Cell / Wound Healing / Keloid / 多能性幹細胞 / 組織幹細胞 / リプログラミング / 幹細胞 / linkage analysis / apoptosis / animal model / cerebral aneurysm / 連鎖解析 / アポトーシス / TMD / ストレス蛋白 / 顎関節症 / gene / endothelium / cerebral aneurysmal / hemodynamic stress / マウス / ラット / 高血圧 / 血行力学的ストレス / 遺伝子 / endothelin / ATP dependent protease / disulfidebond formation / lipoprobin / prion / translocation / ER stress / molecular chperone / タンパク質の膜透過 / シャペロニン / 蛋白質 / 生物物理 / 輸送 / 成熟 / ストレス / ATP依存性プロテアーゼ / ジスルフィド形成 / 外膜リポタンパク質 / プリオン / 蛋白質の膜透過 / 小胞体ストレス / タンパク質分解 / amyloidosis / secretory protein / mitochondria import / folding / hsp47 / 小胞輸送 / hsp70 / アミロイド形成 / Hsp47 / カルネキシン / DnaJホモログ / Hsp70 / タンパク質の細胞内輸送 / 折り畳み / 膜透過 / 葉緑体 / アミロイドーシス / ミトコンドリア輸送 / kinases / Adhesion signal / Proteoglycans / Cell-substratum inteaction / Extracellular matrix / Integrin / Anti-adhesion / Cell adhesion / 抗一接着 / キナーゼ / 接着シグナル / 細胞基質相互作用 / 抗-接着 / intracellular transport of proteins / protein folding / SOS response / oxidative stress / 蛋白質の細胞内輸送 / Intermolecular Association / Intracellnlar transport / Molecular Biology / Collagen / Structual Analysis / Molecular Chaperone / Stress Protein / Heat Shock Protein / 分子生物学 / 分子間結合 / 細胞内輸送 / CYTOKINE / INTEGRIN / PROTEOGLYCAN / FIBRONECTIN / LAMININ / COLLAGEN / EXTRACELLULAR MATRIX / CELL ADHESION / コラ-ゲン / コンドロイチン硫酸 / サイトカイン / ラミニン / cell defense mechanism / environmental adaptation / temperature-sensitive mutants / domain structure / transcriptional control / stress proteins / 分泌 / タンパク質キナ-ゼ / タンパク質間相互作用 / 突然変異 / 転写制御 / 蛋白質の分泌 / 翻訳調節 / 生体防御機構 / 環境適応機構 / 温度感受性変異株 / ドメイン構造 / 転写調節 / ストレスタンパク質 / Culture embedded in Collagen gel / Fibronectin receptor / Differentiation of chondrocytes / Repair of Articular Cartilage / フィブロンネクチンリセプタ- / フィブロンネクチン / コラ-ゲンゲル内培養 / フィブロネクチンリセプタ- / 軟骨細胞の分化 / 関節軟骨の修復 / 微小管結合タンパク質 / 転移 / タンパク質のリン酸化 / MRスペクトロスコピー / Heat ShocR Protein / 熱耐性 / 熱感受性 / フォールボールエステルの作用 / 有系分列の異常 / 有系分裂異常 / 核内タンパク質 / 基質特異性 / 機能制御 / 構造変化 / タンパク質相互作用 / 反応サイクル / HSP60 / CCT / ATPase / 複合体形成 / 医歯薬学 / 衛生学 / 社会医学 / 遺伝疫学 / 予防医学 / 生体分子 / 炎症 / NF-kB / クモ膜下出血 / 脳血管障害 / 脳神経疾患 / 脳血管障害学(脳動脈瘤 クモ膜下出血 炎症) / トランスロケータ / 機能発現 / 間質制御 / 線維芽細胞 / HSP47 / スキルス / 胃癌 / 遺伝病 / 膜タンパク質 / 動脈硬化 / チャネル / ABCタンパク質 / トランスポーター / 癌 / 糖尿病 / コレステロール / 生活習慣病 / ABC蛋白質 / 摘出潅流心 / 熱ショック転写因子 / 再灌流 / 心筋虚血 / 蛋白質・蛋白質相互作用 / 細胞周期 / ポリホスホイノシタイド / MAPキナ-ゼ / カドヘリン / HSP90 / トリ肉腫ウィルス / 細胞生物学と関連領域 / 動向調査 / 現状分析 / 細胞生物学 Less
  • Research Projects

    (63 results)
  • Research Products

    (200 results)
  • Co-Researchers

    (139 People)
  •  Novel mechanism of the removal of reactive oxygen species in the ERPrincipal Investigator

    • Principal Investigator
      Nagata Kazuhiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      JT Biohistory Research Hall
      Kyoto Sangyo University
  •  Regulation of neuronal ageing through the mTOR signaling by acetylation

    • Principal Investigator
      YASUDA KUNIHIKO
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokai Gakuin University
      Nagasaki University
  •  Mechanism of the maintenance of ER homeostasis by redox regulationPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto Sangyo University
  •  Regulation of cellular functions by highly evolved two chaperonins

    • Principal Investigator
      KUBOTA HIROSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Akita University
  •  The elucidation of mechanisms for myseterin and its susceptibility variant and development of prevention program for moyamoya disease.

    • Principal Investigator
      KOIZUMI Akio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto University
  •  Integrated promotion of the researches in protein community

    • Principal Investigator
      ENDO Toshiya
    • Project Period (FY)
      2007 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Quality control mechanism of misfolded proteins in the ERPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto Sangyo University
      Kyoto University
  •  productive foldingと品質管理によるタンパク質の動態制御Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto University
  •  Clarification of mechanisms and role of inflammation cascade during cerebral aneurysm formation and development

    • Principal Investigator
      HASHIMOTO Nobuo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      National Cardiovascular Center Research Institute
      Kyoto University
  •  Analysis of the molecular function of HtrAl in keloid pathogenesis

    • Principal Investigator
      NAITOH Motoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Kyoto University
  •  Quality control mechanism of misfolded proteinsPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Kyoto Sangyo University
      Kyoto University
  •  Study on stroma of scirrhous gastric carcinoma Down reguration of collagen synthesis by siRNA in tumor tissue

    • Principal Investigator
      KIKUCHI Shiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kitasato University
  •  The molecular mechanisms of initiation, progression, rupture of cerebral aneurysms and development of a preventive treatment for it

    • Principal Investigator
      HASHIMOTO Nobuo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyoto University
  •  Investigation of keloid derived "stem-like" cells to clarify keloid pathogenesis.

    • Principal Investigator
      NAITOH Motoko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Kyoto University
  •  Quality control mechanism for positive and negativePrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University
  •  Research for the role of stress protein in TMD

    • Principal Investigator
      YAMAMURA Isao
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Osaka University
      Kyoto University
  •  ABC蛋白の多機能性と生命維持機構

    • Principal Investigator
      植田 和光
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Molecular mechanism of ER-related degradationPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  分子シャペロンによる基底膜分子構築の操作と癌細胞の浸潤・転移機能の解析Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Life of proteins: maturation, translocation, quality control in the cell

    • Principal Investigator
      YOSHIDA Masasuke
    • Project Period (FY)
      2001 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Institute of Technology
  •  Molecular mechanisms of cerebral aneurysmal formation

    • Principal Investigator
      HASHIMOTO Nobuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyoto University
  •  Two novel chaperone-like proteins involved in ER quality control mechanismPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      KYOTO UNIVERSITY
  •  コラーゲン特異的分予シャペロンHSP47の構造と機能Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University
  •  Regulation of cellular Function by molecular chaperonesPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1997 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      KYOTO UNIVERSITY
  •  Roles of molecular chaperones in cell function

    • Principal Investigator
      MORI Masataka
    • Project Period (FY)
      1997 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  熱ショック転写因子群による分子シャペロンの転写制御機構Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  コラーゲン特異的分子シャペロンによる癌細胞の浸潤転移制御Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  セルピンファミリー蛋白質の分子シャペロン機能Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  分子シャペロンによる細胞機能制御Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Kyoto University
  •  心筋虚血及び再灌流時におけるストレス応答とストレス蛋白質

    • Principal Investigator
      野本 慎一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Kyoto University
  •  Structure and function of stress proteinsPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University, Chest Disease Research Institute
  •  STUDIES ON MOLECULAR MECHANISMS AND PHYSIOLOGICAL FUNCTIONS OF ANTI-CELL ADHESION

    • Principal Investigator
      KIMATA Koji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      INSTITUTE FOR MOLECULAR SCIENCE OF MEDICINE,AICHI MEDICAL UNIVERSITY
  •  The role of substrate-specific molecular chaperone in the trimerization of procollagen.Principal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      KYOTO UNIVERSITY
  •  The role of collagen-specific molecular chaperone HSP47Principal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  熱ショック・ストレス蛋白質の機能、発現機構とその制御Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  Studies on the molecular mechanism of heat shock protein 47.

    • Principal Investigator
      NAKAI Akira
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Overseas Scientific Survey.
    • Research Institution
      Kyoto University
  •  Molecular Mechanism of Stress Response

    • Principal Investigator
      YAHARA Ichiro
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Regulatory mechanism of the expression of vimentin gene during the differentiation of leukemic cells.Principal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      KYOTO UNIVERSITY
  •  熱ショック・ストレス蛋白質の機能、発現制御とその制御Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  がん細胞の特性を決定する細胞骨格異常の生化学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  白血病細胞の分化形質を支配するビメンチン遺伝子の発現調節Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  コラーゲンの小胞体・ゴルジ間輸送におけるHSP47の役割Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  ストレス応答の分子機構

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  The role of stress proteins in the protein biosynthesis.Principal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyoto University
  •  癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  がん細胞の特性を決定する細胞骨格異常の生化学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  コラ-ゲンの小胞体・ゴルジ間輸送におけるHSP47の役割Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Stress response and stress protein

    • Principal Investigator
      YAHARA Ichiro
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      物質生物化学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  THE ANALYSIS OF CELL ADHESION SIGNALS : POSSIBLE CLINICAL APPLICATIONS

    • Principal Investigator
      HAYASHI Toshikiko
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      UNIVERSITY OF TOKYO
  •  癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  がん細胞の特性を決定する細胞骨格異常の生化学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  細胞生物学研究推進のための調査研究

    • Principal Investigator
      田代 裕
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Kansai Medical University
  •  Development of "Hybrid Type" Artificial Articular Cartilage

    • Principal Investigator
      OKA Masanori
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kytot University
  •  温熱耐性の発現機構の解明とその修飾に関する研究

    • Principal Investigator
      田中 敬正
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  細胞がん化に伴う細胞骨格異常の分子生物学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  温熱耐性克服のための熱ショック蛋白質の基礎的研究Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  細胞接着因子と細胞機能調節

    • Principal Investigator
      MASAO Hayashi
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Ochanomizu University
  •  細胞がん化に伴なう細胞骨格異常の分子生物学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  がん細胞の温熱耐性における熱ショック蛋白質の役割Principal Investigator

    • Principal Investigator
      永田 和宏
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  細胞がん化に伴なう細胞骨格異常の分子生物学的解析

    • Principal Investigator
      矢原 一郎
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Physiology and Biochemistry of Fibronectin; Comprehensive Approaches from Basic to Clinical Studies.

    • Principal Investigator
      MASAO Hayashi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      Ochanomizu University
  •  Biochemical and molecular biological research for the function and regultion of a collagen receptorPrincipal Investigator

    • Principal Investigator
      NAGATA Kazuhiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation Book Patent

  • [Book] Redox-dependent protein quality control in the ER : folding to degrasation2012

    • Author(s)
      M. Hagiwara and K. Nagata
    • Publisher
      Antioxidants & Redox Signaling
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] ER stress proteins in autoimmune and inflammatory diseases2012

    • Author(s)
      D. Morito and K. Nagata
    • Total Pages
      48
    • Publisher
      Frontiers in Inflammation
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] Autophagy2012

    • Author(s)
      D.J. Klionsky, F. C. AbdallaK, H. Abeliovich,R. T. Abraham, K. Nagata et al
    • Total Pages
      100
    • Publisher
      LANDES BIOSCIENCE
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Book] Cold Spring Harbor Perspectives in Biology "Protein Homeostasis"2011

    • Author(s)
      K. Araki, K. Nagata, 他 分担執筆
    • Total Pages
      349
    • Publisher
      Cold Spring Harbor Laboratory press(分担執筆)
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] Protein Folding and Quality Control in the ER Cold Spring Harbor Perspectives inBiology"Protein Homeostasis"2011

    • Author(s)
      K. Araki and K. Nagata
    • Publisher
      Cold SpringHarbor Laboratory press
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] Cold Spring Harbor Perspectives in Biology" Protein Homeostasis"2011

    • Author(s)
      K.Araki, K.Nagata, 他分担執筆
    • Total Pages
      349
    • Publisher
      Cold Spring Harbor Laboratory press
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] Protein Folding and Quality Control in the ER, Cold Spring Harbor Perspectives in Biology "Protein Homeostasis"2011

    • Author(s)
      K. Araki and K. Nagata
    • Publisher
      Cold Spring Harbor Laboratory press
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] 医学のための細胞生物学2009

    • Author(s)
      永田和宏、塩田浩平(編)
    • Total Pages
      315
    • Publisher
      南由堂
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] ルーイン細胞生物学2009

    • Author(s)
      永田和宏, 他(訳)
    • Total Pages
      681
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] 医学のための細胞生物学2009

    • Author(s)
      永田和宏、塩田浩平(編)
    • Total Pages
      315
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] 医学のための細胞生物学2009

    • Author(s)
      永田和宏、塩田浩平
    • Total Pages
      315
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] 医学のための細胞生物学、315ページ2009

    • Author(s)
      永田和宏, 塩田浩平, 編
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] ルーイン細胞生物学2008

    • Author(s)
      永田和宏, 他(訳)
    • Total Pages
      681
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] ルーイン細胞生物学、681ページ2008

    • Author(s)
      永田和宏, 中野明彦, 米田悦啓, 須藤和夫, 室伏擴, 榎森康文, 伊藤維昭, 訳
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] 蛋白質核酸酵素増刊 キーワード:蛋白質の一生2008

    • Author(s)
      遠藤斗志也, 小椋光, 永田和宏, 森和俊, 田口英樹, 吉田賢右(編)
    • Total Pages
      1114
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Book] ルーイン細胞生物学2008

    • Author(s)
      永田和宏、中野明彦、米田悦啓、須藤和夫、室伏擴、榎森康文、伊藤維昭(訳)
    • Total Pages
      681
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Book] Topics in Current Chemistry : Collagen 2472005

    • Author(s)
      T.KOIDE, K.NAGATA
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-16207013
  • [Book] Topics in Current Chemistry : Collagen 2472005

    • Author(s)
      T.KOIDE, K.NAGATA
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Journal Article] Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors2023

    • Author(s)
      Shohei Fujii , Ryo Ushiodaa and Kazuhiro Nagata
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Journal Article] Ca2+ imbalance caused by ERdj5 deletion affects mitochondrial fragmentation2021

    • Author(s)
      Riyuji Yamashita , Shohei Fujii , Ryo Ushioda , Kazuhiro Nagata
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 20772-20772

    • DOI

      10.1038/s41598-021-99980-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04002, KAKENHI-PLANNED-21H05268
  • [Journal Article] The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets2019

    • Author(s)
      Munechika Sugihara, Daisuke Morito, Shiori Ainuki, Yoshinobu Hirano, Kazutoyo Ogino, Akira Kitamura, Hiromi Hirata, Kazuhiro Nagata
    • Journal Title

      Journal of Cell Biology

      Volume: 218 Issue: 3 Pages: 949-960

    • DOI

      10.1083/jcb.201712120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06201, KAKENHI-PUBLICLY-17H05578, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-16H04657
  • [Journal Article] A BRET-based assay reveals collagen-Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction.2019

    • Author(s)
      S. Ito, M. Saito, M. Yoshida, K. Takeuchi, T. Doi & K. Nagata
    • Journal Title

      J Biol Chem.

      Volume: 294(44) Issue: 44 Pages: 15962-15972

    • DOI

      10.1074/jbc.ra119.010567

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-18K14393
  • [Journal Article] Roles of the endoplasmic reticulum-resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease.2019

    • Author(s)
      Ito S, Nagata K.
    • Journal Title

      J Biol. Chem.

      Volume: 294(6) Issue: 6 Pages: 2133-2141

    • DOI

      10.1074/jbc.tm118.002812

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Journal Article] Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.2018

    • Author(s)
      D. Sepulveda, D. Rojas-Rivera, DA. Rodriguez ,J. Groenendyk, A. Kohler,C. Lebeaupin,S. Ito, H. Urra, A. Carreras-Sureda, Y. Hazari, M. Vasseur-Cognet, MMU. Ali,E. Chevet,G. Campos, P. Godoy,T. Vaisar, B. Bailly-Maitre, K. Nagata,M. Michalak,J. Sierralta,C. Hetz.
    • Journal Title

      Mol Cell.

      Volume: 69 Issue: 2 Pages: 238-252

    • DOI

      10.1016/j.molcel.2017.12.028

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Journal Article] Detection of substrate binding of a collagen-specific molecular chaperone HSP47 in solution using fluorescence correlation spectroscopy.2018

    • Author(s)
      A. Kitamura, Y. Ishida, H. Kubota, CG. Pack, T. Homma, S. Ito, K. Araki, M. Kinjo, K. Nagata
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 497 Issue: 1 Pages: 279-284

    • DOI

      10.1016/j.bbrc.2018.02.069

    • NAID

      120006558991

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Journal Article] Nuclear export of ubiquitinated proteins via the UBIN-POST system2018

    • Author(s)
      S. Hirayama, M. Sugihara, D. Morito, S. Iemura, T. Natsume, K. Nagata
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: in press Issue: 18

    • DOI

      10.1073/pnas.1711017115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-16K20998, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-26000014
  • [Journal Article] A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis2017

    • Author(s)
      S. Ito, K. Ogawa, K. Takeuchi, M. Takagi, M. Yoshida, T. Hirokawa, S. Hirayama, K. Shin-Ya, I. Shimada, T. Doi, N. Goshima, T. Natsume, K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Issue: 49 Pages: 20076-20085

    • DOI

      10.1074/jbc.m117.815936

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-16K20998
  • [Journal Article] Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj52016

    • Author(s)
      R. Ushioda, A. Miyamotod, M. Inoue, S. Watanabe, M. Okumurae, K. Maegawa, K. Uegaki, S. Fujii, Y. Fukuda, M. Umitsu, J. Takagi, K. Inaba, K. Mikoshibad, and K. Nagata
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113(41) Issue: 41 Pages: 6055-6063

    • DOI

      10.1073/pnas.1605818113

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01545, KAKENHI-PUBLICLY-15H01626, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-24227009
  • [Journal Article] Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213.2015

    • Author(s)
      Kotani Y, Morito D, Yamazaki S, Ogino K, Kawakami K, Takashima S, Hirata H, Nagata K.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 16161-16161

    • DOI

      10.1038/srep16161

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07062, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K14373, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-25290008, KAKENHI-PROJECT-15H02370
  • [Journal Article] Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen2015

    • Author(s)
      S. Ito , K. Nagata
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 469 Issue: 3 Pages: 437-442

    • DOI

      10.1016/j.bbrc.2015.12.028

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Journal Article] Deletion of the Collagen-specific Molecular Chaperone Hsp47 Causes Endoplasmic Reticulum Stress-mediated Apoptosis of Hepatic Stellate Cells.2015

    • Author(s)
      Kawasaki K, Ushioda R, Ito S, Ikeda K, Masago Y, Nagata K
    • Journal Title

      J Biol Chem.

      Volume: 290 Issue: 6 Pages: 3639-3646

    • DOI

      10.1074/jbc.m114.592139

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25840079, KAKENHI-PUBLICLY-26111521, KAKENHI-PUBLICLY-15H01545, KAKENHI-PROJECT-24227009
  • [Journal Article] Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques.2015

    • Author(s)
      Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo
    • Journal Title

      International Journal of Molecular Science

      Volume: 16 Issue: 3 Pages: 6076-6092

    • DOI

      10.3390/ijms16036076

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-24227009
  • [Journal Article] Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible?2015

    • Author(s)
      Morito D, Nagata K.
    • Journal Title

      Molecular Cell

      Volume: 59 Issue: 3 Pages: 335-44

    • DOI

      10.1016/j.molcel.2015.06.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07062, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-24227009
  • [Journal Article] Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments.2015

    • Author(s)
      Kirstein J, Morito D, Kakihana T, Sugihara M, Minnen A, Hipp MS, Nussbaum-Krammer C, Kasturi P, Hartl FU, Nagata K, Morimoto RI.
    • Journal Title

      The EMBO Journal

      Volume: 34 Issue: 18 Pages: 2334-49

    • DOI

      10.15252/embj.201591711

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07062, KAKENHI-PROJECT-15K18489, KAKENHI-PUBLICLY-15H01546, KAKENHI-PROJECT-24227009
  • [Journal Article] Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ AT Pase, which dynamically changes its oligomeric state2014

    • Author(s)
      Daisuke Morito, Kouki Nishikawa, Jun Houseki, Akira Kitamura, Yuri Kotani, Kazumi Kiso, Masataka Kinjo, Yoshimori Fujiyoshi & Kazuhiro Nagata
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: Vol. 4 Issue: 1 Pages: 4442-4442

    • DOI

      10.1038/srep04442

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J07825, KAKENHI-PROJECT-23770215, KAKENHI-PROJECT-24227009, KAKENHI-PUBLICLY-25122717, KAKENHI-PROJECT-25840024
  • [Journal Article] Dysregulation of the Proteasome Enhances the Toxicity of ALS-linked Mutant SOD12014

    • Author(s)
      Kitamura, A., Inada, N., Kubota, H., Matsumoto, G., Kinjo, M., Morimoto, R.I., Nagata, K
    • Journal Title

      Genes to Cells

      Volume: 3 Issue: 3 Pages: 209-224

    • DOI

      10.1111/gtc.12125

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23500434, KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-24111554, KAKENHI-PROJECT-24227009
  • [Journal Article] Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia.2014

    • Author(s)
      Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
    • Journal Title

      BMC Pulm. Med.

      Volume: 14 Issue: 1 Pages: 48-48

    • DOI

      10.1186/1471-2466-14-48

    • NAID

      120006986596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
  • [Journal Article] Endoplasmic reticulum lectinXTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsinvariant2013

    • Author(s)
      T. Fujimori, Y. Kamiya, K. Nagata, K. Kato &N. Hosokawa
    • Journal Title

      FEBS J

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis2013

    • Author(s)
      Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
    • Journal Title

      Cell Stress Chaperones

      Volume: 18 Issue: 5 Pages: 581-590

    • DOI

      10.1007/s12192-013-0411-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-23790913, KAKENHI-PROJECT-25860649
  • [Journal Article] Serum heat shock protein 47 levels in patients with drug-induced lung disease.2013

    • Author(s)
      Kakugawa, T., Yokota, S., Ishimatsu, Y., Hayashi, T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Y., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
    • Journal Title

      Respir. Res.

      Volume: 14 Issue: 1 Pages: 133-133

    • DOI

      10.1186/1465-9921-14-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570220, KAKENHI-PROJECT-25860649
  • [Journal Article] Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis.2013

    • Author(s)
      Kakugawa, T., Yokota, S.I., Ishimatsu, Y., Hayashi. T., Nakashima, S., Hara, S., Sakamoto, N., Kubota, H., Mine, M., Matsuoka, Y., Mukae, H., Nagata, K., and Kohno, S.
    • Journal Title

      Cell Stress Chaperones

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570220
  • [Journal Article] Glycosylation-independent ERAD pathway serves as a backup system under ER stress.2013

    • Author(s)
      R.Ushioda, J.Hoseki & K. Nagata
    • Journal Title

      Mol. Biol. Cell.

      Volume: 24(6) Issue: 20 Pages: 861-874

    • DOI

      10.1091/mbc.e13-03-0138

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24121725, KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-25840079
  • [Journal Article] Dynamic Regulation of Erolα and Peroxiredoxin 4 Localization in the Secretory Pathway2013

    • Author(s)
      Taichi Kakihana, Kazutaka Araki, Stefano Vavassori, Shun-ichiro Iemura, Margherita Cortini, Claudio Fagioli, Tohru Natsume, Roberto Sitia and Kazuhiro Nagata
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 288 Issue: 41 Pages: 2958629594-2958629594

    • DOI

      10.1074/jbc.m113.467845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02049, KAKENHI-PROJECT-12J04142, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24227009
  • [Journal Article] Molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation2012

    • Author(s)
      Y. Masago, A. Hosoya, S. Kawano, A. Nasu, J. Toguchida, K. Fujita, H. Nakamura, G. Kondoh and K. Nagata
    • Journal Title

      J. Cell Sci.

      Volume: 125(5) Issue: 5 Pages: 1118-1128

    • DOI

      10.1242/jcs.089748

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-21240049, KAKENHI-PROJECT-21390505, KAKENHI-PROJECT-23659883, KAKENHI-PROJECT-24592785
  • [Journal Article] Pirfenidone inhibits TGF-beta1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells.2012

    • Author(s)
      Hisatomi, K., Mukae, H., Sakamoto, N., Ishimatsu, Y., Kakugawa, T., Hara, S., Fujita, H., Nakamichi, S., Oku, H., Urata, Y., Kubota, H., Nagata, K. and Kohno, S.
    • Journal Title

      BMC Pulm. Med.

      Volume: 12 Issue: 1

    • DOI

      10.1186/1471-2466-12-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570220
  • [Journal Article] The mutation incyclophilin B that causes hyperelastosis cutis in the American Quarter Horse does not affectpeptidyl-prolyl cis-trans isomerase activity, butshows altered cyclophilin B-protein interactionsand affects collagen folding2012

    • Author(s)
      Y. Ishikawa, J. A. Vranka, S. P. Boudko, E.Pokidysheva, K. Mizuno, K. Zientek, D. R.Keene, A. M. Rashmir-Raven, K. Nagata, N. J.Winand and H. P. Bachinger
    • Journal Title

      J. Biol. Chem

      Volume: 287(26) Issue: 26 Pages: 22253-22265

    • DOI

      10.1074/jbc.m111.333336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-24227009
  • [Journal Article] NMR and mutational identification of the collagen-binding site of the chaperone Hsp47.2012

    • Author(s)
      Maho Yagi-Utsumi, Sumi Yoshikawa, Yoshiki Yamaguchi, Yohei Nishi, Eiji Kurimoto, Yoshihito Ishida, Takayuki Homma, Jun Hoseki, Yoshimi Nishikawa, Takaki Koide, Kazuhiro Nagata, Koichi Kato.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 9 Pages: e45930-e45930

    • DOI

      10.1371/journal.pone.0045930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23870043, KAKENHI-PROJECT-24227009, KAKENHI-PLANNED-20107004
  • [Journal Article] Direct in vitro and in vivo evidence for interaction between Hsp47 protein and collagen triple helix2012

    • Author(s)
      T. Ono, T. Miyazaki, Y. Ishida, M. Uehata and K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 287(9) Issue: 9 Pages: 6810-6818

    • DOI

      10.1074/jbc.m111.280248

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] Functional in vitro analysis of ERO1 and protein-disulfide isomerase (PDI) pathway2011

    • Author(s)
      K. Araki and K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 286(37) Issue: 37 Pages: 32705-32712

    • DOI

      10.1074/jbc.m111.227181

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj52011

    • Author(s)
      M.Hagiwara, K.Nagata, et al
    • Journal Title

      Mol.Cell

      Volume: 41 Pages: 432-444

    • NAID

      120003836694

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj52011

    • Author(s)
      M. Hagiwara, K. Maegawa, M. Suzuki, R. Ushioda, K. Araki, Y. Matsumoto, J. Hoseki, K. Nagata and K. Inaba
    • Journal Title

      Mol. Cell

      Volume: 41(4) Issue: 4 Pages: 432-444

    • DOI

      10.1016/j.molcel.2011.01.021

    • NAID

      120003836694

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-23770158
  • [Journal Article] Identification of RNF213 as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development2011

    • Author(s)
      Wanyang Liu, et al
    • Journal Title

      PLoS ONE

      Volume: 6(7) Issue: 7 Pages: e22542-e22542

    • DOI

      10.1371/journal.pone.0022542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00427, KAKENHI-PROJECT-10J05192, KAKENHI-PROJECT-19GS0314, KAKENHI-PROJECT-22249020, KAKENHI-PROJECT-22590817, KAKENHI-PROJECT-22710193, KAKENHI-PUBLICLY-23122520, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-23659329
  • [Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010

    • Author(s)
      Y. Sugiura, K. Araki, 1 S. Iemura, T. Natsume,. J. Hoseki., K. Nagata
    • Journal Title

      J. Biol. Chem 285(10)

      Pages: 7135-7142

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity.2010

    • Author(s)
      Y. Sugiura, K. Araki, 1 S. Iemura, T. Natsume,. J. Hoseki, K. Nagata
    • Journal Title

      J. Biol. Chem. 285(10)

      Pages: 7135-7142

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010

    • Author(s)
      Y. Sugiura, K. Araki, S. Iemura, T. Natsume, J. Hoseki1 and K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 285(10) Issue: 10 Pages: 7135-7142

    • DOI

      10.1074/jbc.m109.082545

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] The novel thioredoxin-related transmembrane protein TMX4 has reductase activity2010

    • Author(s)
      Y.Sugiura, K.Nagata, et al
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 7135-7142

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Solution structure and dynamics of mouse ARMET2010

    • Author(s)
      J.Hoseki, K.Nagata, et al
    • Journal Title

      FEBS.Letters.

      Volume: 584 Pages: 1536-1542

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Solution structure and dynamics of mouse ARMET2010

    • Author(s)
      J. Hoseki, H.Sasakawa, Y. Yamaguchi, M. Maeda, H. Kubota, K. Kato and K. Nagata
    • Journal Title

      FEBS. Letters

      Volume: 584 Issue: 8 Pages: 1536-1542

    • DOI

      10.1016/j.febslet.2010.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] Human 0S-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009

    • Author(s)
      N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato, K. Nagata
    • Journal Title

      J. Biol. Chem. 284(25)

      Pages: 17061-17068

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection2009

    • Author(s)
      Y. Ishida, A. Yamamoto, A. Kitamura, S. R. Lamande, T. YoshimorI, F. B. John, H. Kubota, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 20

      Pages: 2744-2754

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans.2009

    • Author(s)
      N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato, K. Nagata
    • Journal Title

      J. Biol. Chem. 284(25)

      Pages: 17061-17068

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection2009

    • Author(s)
      Y.Ishida, A.Yamamoto, A.Kitamura,S.R.Lamande, T.YoshimorI, F.B.John, H.Kubota and K.Nagata
    • Journal Title

      Mol. Biol. Cell.

      Volume: 20 Issue: 11 Pages: 2744-2754

    • DOI

      10.1091/mbc.e08-11-1092

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.2009

    • Author(s)
      Y. Ishida, A. Yamamoto, A. Kitamura, S.R. Lamande, T. YoshimorI, F.B. John, H. Kubota, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 20

      Pages: 2744-2754

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-Glycans2009

    • Author(s)
      N. Hosokawa, Y. Kamiya, D. Kamiya, K. Kato & K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 284(25) Issue: 25 Pages: 17061-17068

    • DOI

      10.1074/jbc.m809725200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314, KAKENHI-PLANNED-20107004
  • [Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER2008

    • Author(s)
      R.Ushioda, J.Hoseki, K.Araki, G.Jansen, D.Y.Thomas and K.Nagata
    • Journal Title

      Science

      Volume: 321(5888) Issue: 5888 Pages: 569-572

    • DOI

      10.1126/science.1159293

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.2008

    • Author(s)
      R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D. Y. Thomas, K. Nagata
    • Journal Title

      Science 321(5888)

      Pages: 569-572

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF5082008

    • Author(s)
      D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai and K. Nagata
    • Journal Title

      Mol. Biol. Cell.

      Volume: 19 Issue: 4 Pages: 1328-1336

    • DOI

      10.1091/mbc.e07-06-0601

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.2008

    • Author(s)
      R. Ushioda, J. Hoseki, K. Araki, G. Jansen, D.Y. Thomas, K. Nagata
    • Journal Title

      Science 321(5888)

      Pages: 569-572

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.2008

    • Author(s)
      S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D.M. Cyr, H. Kubota, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 19

      Pages: 899-911

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF508.2008

    • Author(s)
      D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D.M. Cyr, K. Tanaka, K. Iwai, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 19

      Pages: 1328-1336

    • Data Source
      KAKENHI-PLANNED-19058008
  • [Journal Article] Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP2008

    • Author(s)
      N.Hosokawa, I.Wada, K.Nagasawa, T.Moriyama, K.Okawa, and K.Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 283(30) Issue: 30 Pages: 20914-20924

    • DOI

      10.1074/jbc.m709336200

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] Gp78 cooperates with RMA1 in ER-associated degradation of CFTRΔF5082008

    • Author(s)
      D. Morito, K. Hirao, F. Tokunaga, N. Hosokawa, D. M. Cyr, K. Tanaka, K. Iwai, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 19

      Pages: 1328-1336

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination2008

    • Author(s)
      S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D. M. Cyr, H. Kubota and K. Nagata
    • Journal Title

      Mol. Biol. Cell.

      Volume: 19 Issue: 3 Pages: 899-911

    • DOI

      10.1091/mbc.e07-07-0631

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058008, KAKENHI-PROJECT-19GS0314
  • [Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination2008

    • Author(s)
      S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D. M. Cyr, H. Kubota, K. Nagata
    • Journal Title

      Mol. Biol. Cell. 19

      Pages: 899-911

    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Journal Article] Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.2006

    • Author(s)
      A.Kitamura, H.Kubota, C.Pack, G.Matsumoto, S.Hirayama, Y.Takahashi, H.Kimura, M.Kinjo, R.Morimoto, K.Nagata
    • Journal Title

      Nature Cell Biol. 8(10)

      Pages: 1163-1169

    • NAID

      120005549596

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Specific recognition of the collagen triple helix by chaperone HSP47 : minimal structural requirement and spatial molecular orientation.2006

    • Author(s)
      Koide, T., Asada, S., Takahara, Y., Nishikawa, Y., Nagata, K., Kitagawa, K.
    • Journal Title

      J.Biol.Chem. 281(6)

      Pages: 3432-3438

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.2006

    • Author(s)
      Oda, Y., Okada, T., Yoshida, H., Kaufman, R.J., Nagata, K., Mori, K.
    • Journal Title

      J.Cell Biol. 172(3)

      Pages: 383-393

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Crytosolic chaperonin protects folding intermediates of Gβ from aggregation by recognizing hydrophobic β-strands2006

    • Author(s)
      S.Kubota, H.Kubota, K.Nagata
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103(22)

      Pages: 8360-8365

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.2006

    • Author(s)
      Y.Oda, T.Okada, H.Yoshida, R.J.Kaufman, K.Nagata, K.Mori
    • Journal Title

      J. Cell Biol. 172

      Pages: 383-393

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] The maintenance of the endoplasmic reticulum network is regulated by p47, a cofactor of p97, through phosphorylation by cdc2 kinase.2005

    • Author(s)
      Kano, F., Kondo, H., Yamamoto, A., Tanaka, A.R., Hosokawa, N., Nagata, K., Murata, M.
    • Journal Title

      Genes Cells 10(4)

      Pages: 333-344

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage.2005

    • Author(s)
      Naitoh M, Kubota H, Ikeda M, Tanaka T, Shirane H, Suzuki S, Nagata K.
    • Journal Title

      Genes. Cells. 10(11)

      Pages: 1081-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591874
  • [Journal Article] ene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage.2005

    • Author(s)
      NAITOH, H.KUBOTA, M.IKEDA, T.TANAKA, H.SIRANE, S.SUZUKI., K.NAGATA.
    • Journal Title

      Genes Cells 10(10)

      Pages: 1081-1091

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] pecific recognition of the collagen triple helix by chaperone HSP47.Minimal structural requirement and spatial molecular orientation.2005

    • Author(s)
      T, KOIDE, S.ASADA, Y.TAKAHARA, Y.NISHIKAWA, K.NAGATA., K.KITAGAWA.
    • Journal Title

      J.Biol.Chem 281(6)

      Pages: 3432-3438

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] 2005, Retropharyngeal lymph node metastasis from oral cancer : A report of two patients2005

    • Author(s)
      M.Nishida, S.Yasuda, K.Murakami, I.Yamamura, Y.Nagata, T.Iizuka
    • Journal Title

      J Oral Maxillofac Surg 63(3)

      Pages: 410-412

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent reformation of the ER network.2005

    • Author(s)
      KANO, H.KONDO, A.YAMAMOTO, Y.KANEKO, K.UCHIYAMA, N.HOSOKAWA, K.NAGATA, M.MURATA.
    • Journal Title

      Genes Cells 10(10)

      Pages: 989-999

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Proinsulin lacking the A7-B7 disulfide bond, Ins2 Akita, tends to aggregate due to the exposed hydrophobic surface.2005

    • Author(s)
      Yoshinaga T, Nakatome K, Nozaki J, Naitoh M, Hoseki J. Kubota H, Nagata K, Koizumi A.
    • Journal Title

      Biological Chemistry. 386(11)

      Pages: 1077-85

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591874
  • [Journal Article] The maintenance of the endoplasmic reticulum network is regulated by p47, a cofactor of p97, through phosphorylation by cdc2 kinase.2005

    • Author(s)
      KANO, H.KONDO, A.YAMAMOTO, AR.TANAKA, N.HOSOKAWA, K.NAGATA., M.MURATA.
    • Journal Title

      Genes Cells 10(4)

      Pages: 333-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy.2004

    • Author(s)
      OHASHI, H.ABE, T.TAKAHASHI, Y.YAMAMOTO, M.TAKEUCHI, H.ARAI, K.NAGATA, T.KITA, H.OKAMOTO, H.YAMAMOTO, T.DOI.
    • Journal Title

      J.Biol.Chem. 279(19)

      Pages: 19816-19823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Accumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-Knockout mouse embryos2004

    • Author(s)
      K.NAGATA et al.
    • Journal Title

      J.Cell.Sci. 117

      Pages: 5913-5922

    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] CHOP induces death by promoting protein synthesis and oxidation in thestressed endoplasmic reticulum2004

    • Author(s)
      S.J.MARCINIAK, C.Y.YUN, S.OYADOMARI, I.NOVOA, Y.ZHANG, R.JUNGREIS, K.NAGATA, H.P.HARDING., D.RON.
    • Journal Title

      Genes Develop. 18(24)

      Pages: 3066-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy2004

    • Author(s)
      K.NAGATA et al.
    • Journal Title

      J.Biol.Chem 279・19

      Pages: 19816-19823

    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Characterization of multiple members of the HSP70-family in platytish culture cells2004

    • Author(s)
      K.NAGATA et al.
    • Journal Title

      Gene 336

      Pages: 207-218

    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Accumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-knockout mouse embryos through the induction of CHOP.2004

    • Author(s)
      T.MARUTANI, A.YAMAMOTO, N.NAGAI, H.KUBOTA, K.NAGATA
    • Journal Title

      J.Cell.Sci. 117

      Pages: 5913-5922

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] Insufficient folding of type IV collagen nad formation of abnormal basement membrane-like structure in embryoid bodies derived from HSP47-null ES cells.2004

    • Author(s)
      MATSUOKA, H.KUBOTA, E.ADACHI, N.NAGAI, T.MARUTANI, N.HOSOKAWA., K.NAGATA.
    • Journal Title

      Mol.Biol.Cell. 15

      Pages: 4467-4475

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] haracterization of multiple members of the HSP70 family in platyfishculture cells : molecular evolution of stress protein HSP70 in vertebrates.2004

    • Author(s)
      YAMASHITA, K.HIRAYOSHI., K.NAGATA.
    • Journal Title

      Gene 336

      Pages: 207-218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] ccumulation of type IV collagen in dilated endoplasmic reticulum leads to apoptosis HSP47-knockout mouse embryos through the induction of CHOP.2004

    • Author(s)
      MARUTANI, A.YAMAMOTO, N.NAGAI, H.KUBOTA., K.NAGATA.
    • Journal Title

      J.Cell.Sci. 117

      Pages: 5913-5922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells.2004

    • Author(s)
      NOZAKI, H.KUBOTA, H.YOSHIDA, M.NAITOH, J.GOJO, T.YOSHINAGA, K.MORI, A.KOIZUMI., K.NAGATA.
    • Journal Title

      Genes Cells 9

      Pages: 261-270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] Insufficient folding of type IV collagen and formation of abnormal basement membrane-like structure in embryoid bodies derived from HSP47-null ES cells.2004

    • Author(s)
      Y.MATSUOKA, H.KUBOTA, E.ADACHI, N.NAGAI, T.MARUTANI, N.HOSOKAWA, K.NAGATA
    • Journal Title

      Mol.Biol.Cell. 15

      Pages: 4467-4475

    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] The ER stress response in stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells2004

    • Author(s)
      K.NAGATA et al.
    • Journal Title

      Genes Cells 9

      Pages: 261-270

    • Data Source
      KAKENHI-PROJECT-16591992
  • [Journal Article] EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin.2003

    • Author(s)
      Y. ODA, N. HOSOKAWA, I. WADA & K. NAGATA
    • Journal Title

      Science 299(5611)

      Pages: 1394-1397

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin.2003

    • Author(s)
      Y. ODA, N. HOSOKAWA, I. WADA & K. NAGATA
    • Journal Title

      Science 299 (5611)

      Pages: 1394-1397

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13053101
  • [Journal Article] HSP47 as a collagen-specific molecular chaperone : function and expression in normal mouse development.2003

    • Author(s)
      K. Nagata
    • Journal Title

      Seminars in Cell and Developmental Biology 14

      Pages: 275-282

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Journal Article] HSP47 as a collagen-specific molecular chaperone : function and expression in normal mouse development.2003

    • Author(s)
      K. Nagata
    • Journal Title

      Seminars In Cell and Developmental Biology 14

      Pages: 275-282

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Patent] 細胞内の異常物質蓄積を伴う疾患の治療薬、バイオマーカー、診断薬、並びに、スクリーニング方法2015

    • Inventor(s)
      永田和宏、山本洋平
    • Industrial Property Rights Holder
      京都産業大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-174597
    • Filing Date
      2015-09-04
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Patent] 2-ヒドロキシベンズアルデヒド化合物、これを含有するコラーゲン細胞外分泌阻害剤及び医薬品組成物2012

    • Inventor(s)
      夏目徹、永田和宏、伊藤進也、土井隆行、吉田将人
    • Industrial Property Rights Holder
      夏目徹、永田和宏、伊藤進也、土井隆行、吉田将人
    • Industrial Property Number
      2012-163835
    • Filing Date
      2012-07-24
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Patent] カルシウムポンプ制御物質のスクリーニング方法、メラニン色素合成阻害物質のスクリーニング方法、ベクター、並びに、細胞2012

    • Inventor(s)
      潮田亮、永田和宏
    • Industrial Property Rights Holder
      潮田亮、永田和宏
    • Industrial Property Number
      2012-176344
    • Filing Date
      2012-08-08
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Patent] モヤモヤ病関連遺伝子及びその利用2010

    • Inventor(s)
      小泉昭夫、永田和宏、森戸大介、高島成二、山崎悟、橋本信夫、松浦範夫、人見敏明
    • Industrial Property Rights Holder
      京都大学
    • Filing Date
      2010-10-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22249020
  • [Presentation] レドックス制御を介した小胞体ストレスセンサー制御機構の解明2022

    • Author(s)
      和田 匠太 , 永田 和宏 , 潮田 亮
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Zinc-dependent functional switching of ERp18, a novel ER thioredoxin2022

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      FASEB Meeting“The Protein Folding in the Cell Conference”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] 小胞体レドックス環境を構築するグルタチオン輸送機構の解明2022

    • Author(s)
      堤 智香 , 田原 諒佑 , 坂本 龍太 , 渡邊 弘樹 , 永田 和宏 , 潮田 亮
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] 小胞体レドックス環境を構築するグルタチオン供給機構の解明2021

    • Author(s)
      堤智香 , 田原諒佑 , 永田和宏 , 潮田亮
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] 新たな小胞体ストレスセンサーATF6制御機構の解明2021

    • Author(s)
      和田 匠太 , 潮田 亮 , 永田 和宏
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] ストレス応答としての小胞体レドックスシフトと恒常性維持2021

    • Author(s)
      潮田亮 , 上垣日育 , 山下龍志 , 永田和宏
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] 小胞体レドックス環境を構築するグルタチオン輸送機構の解明2020

    • Author(s)
      堤 智香 , 潮田 亮 , 永田 和宏
    • Organizer
      第72回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Maintenaice of ER homeostasis through disulfide reductase2019

    • Author(s)
      Ryo Ushioda, Kaiku Uegaki and Kazuhiro Nagata
    • Organizer
      Gordon Research Conference"2019 Stress Proteins in Growth, Development and Desease"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Protein folding and misfolding in the Endoplasmic Reticulum2019

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      EMBO workshop “Protein quality control: From mechanisms to disease”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Nascent polypeptide as a souse of reductive power in the ER2018

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      International Symposium "Proteins:from the Cradle to the Grave"
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Role of ER J protein for the maintenance of ER homeostasis2018

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      International workshop of CSSI
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] ERdj5 as a master regulator of the ER homeostasis: crosstalk of Ca2+ and redox homeostasis2018

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      FASEB Meeting "Protein Research Conferences"
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Redox-mediated regulation of ER homeostasis2018

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      Cold Spring Harbor Meeting “Protein Homeostasis in Health and Disease”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04002
  • [Presentation] Protein Quality Control in the Endoplasmic Reticulum2017

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      Protein Society Annual Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Presentation] Crosstalk among protein, redox and calcium homeostasis in the ER2015

    • Author(s)
      Kazuhio Nagata
    • Organizer
      JSCB Presympojium”Cutting-edge of stress-response and protein homeostasis”
    • Place of Presentation
      Nara(Japan)
    • Year and Date
      2015-06-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Presentation] ERdj5, an ER-resident reductase, regulates the activity of SERCA2, a calcium ATPase, in a [Ca2+]-dependent manner2015

    • Author(s)
      Kazuhio Nagata
    • Organizer
      EMBO conference”Molecular chaperones : From molecules to cells and misfolding deseases”
    • Place of Presentation
      Crete(Greece)
    • Year and Date
      2015-05-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Presentation] Regulation of collagen synthesis by Hsp47 and P4H in combination with specific inhibitors2013

    • Author(s)
      K.Nagata
    • Organizer
      Gordon Research Conferences”Collagen”
    • Place of Presentation
      New London(USA)
    • Year and Date
      2013-07-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Presentation] Two distinct ERAD pathways formisfolded glycoproteins and non-glycoproteins SFB5942012

    • Author(s)
      K. Nagata
    • Organizer
      3^<rd>International Symposium on Molecular Machines in Protein Folding and Protein Transport
    • Place of Presentation
      Munich(Germany)
    • Year and Date
      2012-07-24
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Two distinct ERAD pathways for misfolded glycoproteins and non‐glycoproteins2012

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      SFB594 3rd International Symposium on Molecular Machines in Protein Folding and Protein Transport
    • Place of Presentation
      Munich(Germany)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24227009
  • [Presentation] Regulation and structure of a novelAAA+/ubiquitin ligase protein2012

    • Author(s)
      K. Nagata
    • Organizer
      mysterin EMBO/EMBL Symposium"QualityControl-From Molesules to Organelles"
    • Place of Presentation
      Heiderberg(Germany)
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Regulation of redox homeostasisin the ER2012

    • Author(s)
      K. Nagata
    • Organizer
      Cold Spring Harbor Meeting,Molecular Chaperones & Stress Responses
    • Place of Presentation
      Cold Spring Harbor(USA)
    • Year and Date
      2012-05-02
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] もやもや病感受性遺伝子であるATPase/ユビキチンリガーゼMysterinの生化学的検討2012

    • Author(s)
      人見敏明、森戸大介、劉万洋、小林果、原田浩二、永田和宏、小泉昭夫
    • Organizer
      第82回日本衛生学会学術総会
    • Place of Presentation
      京都大学
    • Data Source
      KAKENHI-PROJECT-22249020
  • [Presentation] Protein quality control and proteostasis in the ER2011

    • Author(s)
      K.Nagata
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou (China)(招待講演)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Two distinct ERAD pathways contribute for maintaining the protein homeostasis in the EREMBO Conference2011

    • Author(s)
      K. Nagata
    • Organizer
      The biology of Molecular Chaperones
    • Place of Presentation
      Grundlsee(Austria)
    • Year and Date
      2011-05-22
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Regulation of redoxhomeostasis in the ER2011

    • Author(s)
      K. Nagata and R. Sitia
    • Organizer
      Conference on QualityControl: Folding and Degradation of Proteins inthe Endoplasmic Reticulum
    • Place of Presentation
      Ascona(Switzerland)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Protein quality control andproteostasis in the ER2011

    • Author(s)
      K. Nagata
    • Organizer
      Cold Spring Harbor Asia Conference,"Protein Homeostasis in Health &Disease"
    • Place of Presentation
      Suzhou(China)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Regulation of redox homeostasis in the ER2011

    • Author(s)
      K. Nagata and R. Sitia
    • Organizer
      Conference on Quality Control: Folding and Degradation of Proteins in the Endoplasmic Reticulum
    • Place of Presentation
      Ascona(Switzerland)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Protein quality control in the ER and the nucleus2011

    • Author(s)
      K. Nagata
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Lucca (Italy)(招待講演)
    • Year and Date
      2011-07-19
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Protein quality control and proteostasis in the ER2011

    • Author(s)
      K. Nagata
    • Organizer
      Cold Spring Harbor Asia Conference, "Protein Homeostasis in Health & Disease"
    • Place of Presentation
      Suzhou(China)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Two distinct ERAD pathways contribute for maintaining the protein homeostasis in the ER2011

    • Author(s)
      K. Nagata
    • Organizer
      EMBO Conference "The biology of Molecular Chaperones"
    • Place of Presentation
      Grundlsee(Austria)
    • Year and Date
      2011-05-22
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] 新規巨大ATP アーゼ/ ユビキチンリガーゼMysterin は血管新生を制御し,モヤモヤ病(ウイリス動脈輪閉塞症)に関与する2010

    • Author(s)
      森戸大介、劉万洋、山崎悟、人見敏明、小林果、松浦範夫、箸方宏州、原田浩二、高島成二、宮本享、橋本信夫、小泉昭夫、永田和宏
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-22249020
  • [Presentation] Regulation in the electron transfer cascade among the oxidoreductases in the endoplasmic reticulum2010

    • Author(s)
      K. Nagata
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Quality control & Redox regulatory network2010

    • Author(s)
      K. Araki,R. Ushioda,J. Hoseki and K.Nagata
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Lucca (Italy)
    • Year and Date
      2010-05-11
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Quality control & Redox regulatory network2010

    • Author(s)
      K. Araki, R. Ushioda, J. Hoseki and K. Nagata
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Lucca (Italy)
    • Year and Date
      2010-05-11
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Regulation in the electron transfer cascade among the oxidoreductases in the endoplasmic reticulum2010

    • Author(s)
      K. Nagata
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Regulation in the electron transfer cascade among the oxidor eductases in the endoplasmic reticulum2010

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      The 3^<rd> International Symposium on Protein Community
    • Place of Presentation
      Nara (Japan)
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Revisiting of collagen-specificmolecular chaperone Hsp47:Fate of procollagenwith or without Hsp472009

    • Author(s)
      K. Nagata
    • Organizer
      Yokosuka Science Festa 2009 8th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Opening Lecture, Shonan
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Quality control of misfolded proteins in the endoplasmic reticulum2009

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai(China)
    • Year and Date
      2009-08-05
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Revisiting of collagen-specific molecular chaperone Hsp47:Fate of procollagen with or without Hsp472009

    • Author(s)
      K. Nagata
    • Organizer
      Yokosuka Science Festa 2009 8th Pan-Pacific Connective Tissue Societies Symposium. Opening Lecture
    • Place of Presentation
      Shonan
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Two distinct ERAD pathways for misfolded glycoprotein and non-glycoprotein2009

    • Author(s)
      K. Nagata
    • Organizer
      4^<th> International Congress on Stress Responses in Biology and Medicine.Plenary lecture
    • Place of Presentation
      Sapporo
    • Year and Date
      2009-10-06
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Quality control of misfoldedproteins in the endoplasmic reticulum2009

    • Author(s)
      K. Nagata
    • Organizer
      21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai(China)
    • Year and Date
      2009-08-05
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Quality control of misfolded proteins in the endoplasmic reticulum.2009

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      21th IUBMB International Congress and 12^th FAOBMB Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai (China)
    • Year and Date
      2009-08-05
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Two distinct ERAD pathways for misfolded glycoprotein and non-glycoprotein2009

    • Author(s)
      K. Nagata
    • Organizer
      4^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Plenary lecture, Sapporo
    • Year and Date
      2009-10-06
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Quality control of misfolded proteins in the endoplasmic reticulum2009

    • Author(s)
      K. Nagata
    • Organizer
      21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai(China)
    • Year and Date
      2009-08-05
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Quality control of misfolded proteins in the endoplasmic reticulum.2009

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      21th IUBMB International Congress and 12th FAOBMB Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai(China)
    • Year and Date
      2009-08-05
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER;ERAD and autophagy2008

    • Author(s)
      K. Nagata, Y. Masago, Y. Ishida
    • Organizer
      Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold Spring Harbor(USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] ケロイドにおける弾性線維欠損のメカニズム2008

    • Author(s)
      石河利広、内藤素子、久保田広志、池田実香、吉川勝宇、山脇聖子、永田和宏、中邨智之、鈴木茂彦
    • Organizer
      第40回結合組織学会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19592073
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008

    • Author(s)
      K. NAGATA
    • Organizer
      Cold Sring Harbor Meeting
    • Place of Presentation
      Cold Sring Harbor(USA)
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER2008

    • Author(s)
      Kazuhiro Nagata, Yusaku Masago, Yoshihito Ishida
    • Organizer
      ERAD and autophagy Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold Spring Harbor(USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008

    • Author(s)
      Kazuhiro Nagata, Yusaku Masago, Yoshihito Ishida
    • Organizer
      Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER ; ERAD and autophagy2008

    • Author(s)
      Kazuhiro Nagata, et al.
    • Organizer
      Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] 大腸菌多機能プロテアーゼ/シャペロンHtrA/DegPのヒトホモローグの一つHtrA1の発現はケロイドの病期と予後に相関する2008

    • Author(s)
      内藤素子、久保田広志、石河利広、吉川勝宇、山脇聖子、鈴木茂彦、永田和宏
    • Organizer
      第3回臨床ストレス応答学会大会
    • Place of Presentation
      秋田
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-19592073
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47: Alternative degradation pathway of misfolded procollagen in the ER; ERAD and autophagy2008

    • Author(s)
      Kazuhiro Nagata
    • Organizer
      Cold Spring Harbor Meeting
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47 : Alternative degradation pathway of misfolded procollagen in the ER : ERAD and autophagy2008

    • Author(s)
      Kazuhiro Nagata, et al.
    • Organizer
      Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold Spring Harbor(USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Revisiting of collagen-specific molecular chaperone HSP47:Alternative degradation pathway of misfolded procollagen in the ER;ERAD andautophagy2008

    • Author(s)
      K. Nagata,Y. Masago, Y. Ishida
    • Organizer
      Cold Spring Harbor Meeting "Molecular Chaperones and stress Response"
    • Place of Presentation
      Cold SpringHarbor(USA)
    • Year and Date
      2008-05-01
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Thiol reductase ERdj5 accelerates the ER-associated degradation by cleaving intermolecular disulfide bonds of misfolded proteis2007

    • Author(s)
      K.Nagata
    • Organizer
      Gordon Research Conference, Stress Proteins in Growth
    • Place of Presentation
      Development & Desease, Oxford(UK)
    • Year and Date
      2007-08-21
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Collagen-specific molecular chaperone HSP472007

    • Author(s)
      K.Nagata
    • Organizer
      7th Pan Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Cairns(Australia)
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Collagen-specific molecular chaperone HSP472007

    • Author(s)
      K.Nagata
    • Organizer
      7th Pan Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Cairns(Australia)
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] A novel thiol reductase ERdj5 accelerates ER-associated degradation by cleaving the intermolecular disulfide bonds of misfolded proteins2007

    • Author(s)
      K. Nagata
    • Organizer
      FASEB Summer Research Conference, Proteins Folding in the Cell
    • Place of Presentation
      Palm Springs(USA)
    • Year and Date
      2007-07-30
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] Thiol reductase ERdj5 accelerates the ER-associated degradation by cleaving intermolecular disulfide bonds of misfolded proteis2007

    • Author(s)
      K.Nagata
    • Organizer
      Gordon Research Conference, Stress Proteins in Growth,Development & Desease
    • Place of Presentation
      Oxford(UK)
    • Year and Date
      2007-08-21
    • Data Source
      KAKENHI-PLANNED-19058008
  • [Presentation] A novel thiol reductase ERdj5 accelerates ER-associated degradation by cleaving the intermolecular disulfide bonds of misfolded proteins2007

    • Author(s)
      K. Nagata
    • Organizer
      FASEB Summer Research Conference, Proteins Folding in the Cell
    • Place of Presentation
      Palm Springs(USA)
    • Year and Date
      2007-07-30
    • Data Source
      KAKENHI-PROJECT-19GS0314
  • [Presentation] Cytosolic Chaperonin CCT : substrate recognition and the role in protein quality control.2006

    • Author(s)
      K. Nagata
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2006-06-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Cytosolic chaperonin CCT/TRiC prevents the aggregation of β-sheet-containing proteins2006

    • Author(s)
      K. Nagata
    • Organizer
      2006 FASEB Summer Research Conferences Protein FoIding in the Cell
    • Place of Presentation
      Vermont (USA)
    • Year and Date
      2006-08-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Cytosolic Chaperonin CCT : substrate recognition and the role in protein quality control.2006

    • Author(s)
      K. Nagata
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Kyoto(Japan)
    • Year and Date
      2006-06-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Cytosolic chaperonin CCT/TRiC prevents the aggregation of β-sheet-containing proteins2006

    • Author(s)
      K. Nagata
    • Organizer
      2006 FASEB Summer Research Conferences Protein Folding in the Cell
    • Place of Presentation
      Vermont(USA)
    • Year and Date
      2006-08-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Several components involved in ER-associated degradation of misfolded glycoproteins2005

    • Author(s)
      K. Nagata
    • Organizer
      International Symposium on Life of Proteins
    • Place of Presentation
      Awaji (Japan)
    • Year and Date
      2005-11-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Different mechanisms of the acceleration of ER-associated degradationby EDEM family proteins.2005

    • Author(s)
      K. Nagata
    • Organizer
      EMBO-FEBS WORKSHOP on Biology of Molecular Chaperones
    • Place of Presentation
      Zakopane (Poland)
    • Year and Date
      2005-05-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associated degradation of misfolded proteins by EDEM and EDEM familyproteins.2005

    • Author(s)
      K. Nagata
    • Organizer
      Second International Congress on stress Responses in Biology and Medicine
    • Place of Presentation
      Tomar(Portugal)
    • Year and Date
      2005-09-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Different mechanisms of the acceleration of ER-associated degradation by EDEM family proteins.2005

    • Author(s)
      K. Nagata
    • Organizer
      EMBO-FEBS WORKSHOP on Biology of Molecular Chaperones
    • Place of Presentation
      Zakopane (Poland)
    • Year and Date
      2005-05-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associated degradation of misfolded proteins by EDEM and EDEM familyproteins.2005

    • Author(s)
      K. Nagata
    • Organizer
      Second International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Tomar (Portugal)
    • Year and Date
      2005-09-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER stress and ER-Associated degradation of misfolded proteins2005

    • Author(s)
      K. Nagata
    • Organizer
      The 18th Naitoh Conference
    • Place of Presentation
      Shonan (Japan)
    • Year and Date
      2005-10-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER stress and ER-Associated degradation of misfolded proteins2005

    • Author(s)
      K. Nagata
    • Organizer
      The 18th Naitoh Conference
    • Place of Presentation
      Shonan(Japan)
    • Year and Date
      2005-10-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Role of collagen-specific molecular chaperone HSP47 in the correct foldingand fibrilformation of procollagens ; lessons from mice and cells disrupted with hsp47 gene.2005

    • Author(s)
      K. Nagata
    • Organizer
      Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2005-12-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Role of collagen-specific molecular chaperone HSP47 in the correct folding and fibril formation of procollagens ; lessons from mice and cells disrupted with hsp47 gene.2005

    • Author(s)
      K. Nagata
    • Organizer
      Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2005-12-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Substrate recognition by HSP47, a collagen-specific molecular chaperone, as amember of serpin superfamily.2005

    • Author(s)
      K. Nagata
    • Organizer
      The 4th International Symposium on Serpin
    • Place of Presentation
      Cairns (Australia)
    • Year and Date
      2005-06-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Substrate recognition by HSP47, a colagen-specific molecular chaperone, as amember of serpin superfamily.2005

    • Author(s)
      K. Nagata
    • Organizer
      The 4th International Symposium on Serpin
    • Place of Presentation
      Cairns(Australia)
    • Year and Date
      2005-06-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associate degradation : EDEM, soluble EDEM and more. . .2004

    • Author(s)
      K. Nagata
    • Organizer
      The 1st Pacific-Rim International Conference on Protein Science
    • Place of Presentation
      Yokohama(Japan)
    • Year and Date
      2004-04-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Is EDEM a lectin-like chaperone involved in ERAD? --EDEM, soluble EDEM and more...2004

    • Author(s)
      K. Nagata
    • Organizer
      Cold Spring Harbor Meeting" Molecular Chaperones and the Heat Shock Response" Cold Spring Harbor
    • Place of Presentation
      USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associate degradation EDEM, soluble EDEM and more...2004

    • Author(s)
      K. Nagata
    • Organizer
      The 1st Pacific-Rim International Conference on Protein Science
    • Place of Presentation
      Yokohama (Japan)
    • Year and Date
      2004-04-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Is EDEM a lectin-like chaperone involved in ERAD? -EDEM, soluble EDEM and more…2004

    • Author(s)
      K. Nagata
    • Organizer
      Cold Spring Harbor Meeting"Molecular Chaperones and the Heat Shock Response"
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] HSP47 : as a key molecule for molecular maturation of procollagen.2003

    • Author(s)
      K. Nagata
    • Organizer
      5th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Ube (Japan)
    • Year and Date
      2003-06-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associated degradation : Possible function of EDEM.2003

    • Author(s)
      K. Nagata
    • Organizer
      10th Congress of the Federation of Asian and Oceanic Biochemists and Molecular Biologists
    • Place of Presentation
      Bangalore(lndia)
    • Year and Date
      2003-12-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] HSP47 : as a key molecule for molecular maturation of procollagen.2003

    • Author(s)
      K. Nagata
    • Organizer
      5th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Ube
    • Year and Date
      2003-06-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] HSP47 is essential for the molecular maturation of collagens and the formation of basement membranes.2003

    • Author(s)
      K. Nagata
    • Organizer
      Gordon Research Conferences(Callagen)
    • Place of Presentation
      New London (USA)
    • Year and Date
      2003-07-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] EDEM cooperates with calnexin in the ER associated degradation of unfolded proteins.2003

    • Author(s)
      K. Nagata
    • Organizer
      EURESCO Conferences
    • Place of Presentation
      Tomar(Portugal)
    • Year and Date
      2003-09-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] ER-associated degradation : Possible function of EDEM.2003

    • Author(s)
      K. Nagata
    • Organizer
      10th Congress of the Federation of Asian and Oceanic Biochemists and Molecular Biologists
    • Place of Presentation
      Bangalore(India)
    • Year and Date
      2003-12-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Possible functions od EDEM in the ERAD of terminally misfolded proteins.2003

    • Author(s)
      K. Nagata
    • Organizer
      1st International Congress on stress Responses in Biology and Medicine
    • Place of Presentation
      Quebec(Canada)
    • Year and Date
      2003-09-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Quality Control Mechanism of the Unfolded Proteins in ER.2003

    • Author(s)
      K. Nagata
    • Organizer
      The 7th International Congress(Genes, Gene Families and Isozymes)
    • Place of Presentation
      Berlin (Germany)
    • Year and Date
      2003-07-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] EDEM cooperates with calnexin in the ER associated degradation of unfolded proteins2003

    • Author(s)
      K. Nagata
    • Organizer
      EURESCO Conferences
    • Place of Presentation
      Tomar(Portugal)
    • Year and Date
      2003-09-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Possible functions od EDEM in the ERAD of terminally misfolded proteins.2003

    • Author(s)
      K. Nagata
    • Organizer
      1st International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Quebec (Canada)
    • Year and Date
      2003-09-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Quality Control Mechanism of the Unfolded Proteins in ER2003

    • Author(s)
      K. Nagata
    • Organizer
      The 7th International Congress(Genes, Gene Families and lsozymes)
    • Place of Presentation
      Berlin (Germany)
    • Year and Date
      2003-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] HSP47 is essential for the molecular maturation of collagens and the formation of basement membranes.2003

    • Author(s)
      K. Nagata
    • Organizer
      Gordon Research Conferences(Collagen)
    • Place of Presentation
      New London(USA)
    • Year and Date
      2003-07-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • [Presentation] Quality control of the nascent proteins in the endoplasmic reticulum.2002

    • Author(s)
      K. Nagata
    • Organizer
      The 4th APOCB for Cell Biology Congress
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2002-11-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14037230
  • 1.  YAHARA Ichiro (60109957)
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  • 2.  ENDO Toshiya (70152014)
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
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  • 138.  YAGI Maho
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  • 139.  LIU Wangyang
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