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KUREBAYASHI Nagomi  呉林 なごみ

… Alternative Names

KUREBAYASHI Kunihiro  國廣 なごみ

国廣 なごみ  クニヒロ ナゴミ

KUNIHIRO-KUREBAYASHI Nag  国広 なごみ

呉林 なごみ  クレバヤシ ナゴミ

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Researcher Number 50133335
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5005-9698
External Links
Affiliation (Current) 2025: 順天堂大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 順天堂大学, 医学部, 客員准教授
2019 – 2020: 順天堂大学, 医学部, 非常勤講師
2016 – 2019: 順天堂大学, 医学部, 先任准教授
2011 – 2015: 順天堂大学, 医学部, 准教授
2013: 順天堂大学, 医学部, 教授 … More
2007: Juuntendo University School of Medicine, Department of Pharmacology, Associate Professor
2005 – 2006: 順天堂大学, 医学部, 助教授
1999 – 2003: 順天堂大学, 医学部, 助教授
1998: 順天堂大学, 医学部, 講師
1987 – 1989: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Basic Section 47040:Pharmacology-related / General pharmacology / Complex systems
Except Principal Investigator
Basic Section 59010:Rehabilitation science-related / Basic Section 48020:Physiology-related / Basic Section 59020:Sports sciences-related / General pharmacology / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 56050:Otorhinolaryngology-related … More / Basic Section 43020:Structural biochemistry-related / Integrative animal science / General pharmacology / Neurophysiology and muscle physiology / Legal medicine / Neurophysiology and muscle physiology Less
Keywords
Principal Investigator
カルシウム / 不整脈 / 心臓 / 心筋 / 抗不整脈薬 / 筋小胞体 / リアノジン受容体 / 心不全 / ライブイメージング / 2型リアノジン受容体 … More / Alternans / Na^+ / TRPV6 / Ca^<2+> / ATPase / カテコラミン誘発性多型性心室頻拍 / 拡張型心筋症 / 活動電位 / 創薬 / 機能抑制型変異 / 大規模スクリーニング / 細胞内カルシウム動態 / モデルマウス / RyR2阻害薬 / ハイスループットスクリーニング / ドラッグスクリーニング / RyR2 / CPVT / Atrial fibrillation / Calcium ion / Action potentia / Abnormal conductance / Connexin / Ca^<2+> overload / Arrhythmia / alternans / Ca^2+オーバロード / 心房細動 / 伝導障害 / コネキシン / Ca^<2+>オーバーロード / econazole / Ca^<2+> exchanger / dihydropyridine receptor / laser scanning confocal microscope / store-operated Ca^<2+> entry / skeletal muscle / cardiac muscle / 乳頭筋 / 心室性不整脈 / Ca過負荷 / Ca^<2+> exchange / ECaC / Ca^<2+> wave / エバネッセント顕微鏡 / calcium overload / Ca^<2+>流入 / エコナゾール / Ca^<2+>交換体 / ジヒドロピリジン受容体 / 共焦点顕微鏡 / ストア依存性Ca^<2+>流入 / 骨格筋 / sarcoplasmic reticulum / heart failure / Energy consumption / skinned fiber / heart / カフェイン / Ca^<2+>によるCa^<2+>遊離 / Mg^<2+> / エネルギー消費 / スキンドファイバー / Ca2+インジケータ / 形態解析 / 興奮伝導 / 電流 / イメージング / Ca2+遊離 / 睡眠時無呼吸症候群 / 組織イメージング / 筋節長 / 等尺性張力 / ミオシンATPase / カルシウム感受性 / エネルギ-転換機構 / スキンファイバ- … More
Except Principal Investigator
リアノジン受容体 / 筋小胞体 / 心不全 / カルシウムチャネル / 骨格筋 / イメージング / 心室性不整脈 / カルシウムイオン / 不整脈 / 興奮収縮連関 / 拡張型心筋症 / 運動療法 / クライオ電子顕微鏡 / イオンチャネル / 構造解析 / 筋収縮 / 粘弾性 / 微小管 / 小胞体 / 相互作用 / カルシウム遊離チャネル / マウスモデル / 老化 / カルシウム / 加齢性難聴 / 膜蛋白質 / レニン・アンギオテンシン阻害薬 / 機能解析 / 創薬 / 悪性高熱症 / サブタイプ / 筋挫傷 / 衝撃耐性 / 遺伝子 / 疾患モデル / 臨床心臓学 / マウス / 遺伝性 / 突然死 / Caffeine / Calmodulin Antagonists / Trifluoperazine / Ca^<2+> Sensitivity / ATPase Activity / Tension / Skinned Fiber / カルモジュリン阻害薬 / メリチン / W-7 / クロルプロマジン / スキンドファイバー / カフェイン / カルモデュリン拮抗剤 / トリフルオペラジン / Ca^<2+>感受性 / ATPase活性 / 張力 / スキンドファイバ- / sarcoplasmic reticulum / calcium ion / ryanodine receptor / heart failure / cardiac hypertrophy / 細胞内Ca2+ / カルモジュリン / 細胞内カルシウム / 心肥大 / リガンド結合 / ドメイン / Ca-ATPase / S4-S5リンカー / 人工アミノ酸 / 迷走神経 / ノックインマウス / 抗不安薬 / 抗うつ薬 / 遺伝的要因 / トリプトファン / セロトニン / 脳 / 不安障害 / うつ病 / うっ血性心不全 / β-アドレナリン受容体 / ユビキチン化 / 低酸素 / 認知機能障害 / 歯学 / 性差医学 / 心機能障害 / 間歇的低酸素 / 閉経 / 虚血 / 加齢 / 高血圧 / 間歇低酸素 / アルギナーゼ / 一酸化窒素 / オートファジー / 肺高血圧 / 間歇低酸素暴露 / 睡眠時無呼吸症候群 / 悪性高熱 Less
  • Research Projects

    (27 results)
  • Research Products

    (183 results)
  • Co-Researchers

    (54 People)
  •  創薬へ向けた心筋型リアノジン受容体の活性制御機構の構造的解明

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kyoto University
  •  家族性拡張型心筋症モデルにおける運動療法の効果

    • Principal Investigator
      杉原 匡美
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Juntendo University
  •  骨格筋のしなやかさにおける微小管の役割

    • Principal Investigator
      小林 琢也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Juntendo University
  •  Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agentsPrincipal Investigator

    • Principal Investigator
      呉林 なごみ
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Juntendo University
  •  Role of long-term cellular dysfunction due to abnormal Ca2+ metabolism in presbyopia

    • Principal Investigator
      野島 愛来
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Juntendo University
  •  Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system

    • Principal Investigator
      村山 尚
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Juntendo University
  •  The construction of exercise therapy in familial DCM model mice

    • Principal Investigator
      杉原 匡美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Juntendo University
  •  Structural analysis of the gating mechanism of cardiac ryanodine receptor

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Kyoto University
  •  Role of Microtubules in the Muscle Structure-Contraction Relationship

    • Principal Investigator
      Kobayashi Takuya
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Juntendo University
  •  Effectiveness of RyR2 inhibitors as antiarrhytmic drugsPrincipal Investigator

    • Principal Investigator
      Kurebayashi Nagomi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Juntendo University
  •  Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators

    • Principal Investigator
      Murayama Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Juntendo University
  •  Elucidation of molecular mechanisms of spontaneous sudden cardiac death model mouse due to ventricular arrhythmia

    • Principal Investigator
      Aonuma Kazutaka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Integrative animal science
    • Research Institution
      University of Tsukuba
  •  Establishment of analysis method of ryanodine receptor arrhythmogenic mutations and its application to therapeutic drug screeningPrincipal Investigator

    • Principal Investigator
      Kurebayashi Nagomi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  興奮伝導・不整脈発生における心筋組織の細胞間不均一性の関与Principal Investigator

    • Principal Investigator
      呉林 なごみ
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Juntendo University
  •  Elucidation of regulatory mechanisms of type 2 ryanodine receptors by introducing artificial amino acids

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  Exploration of anti-arrhythmic drugs acting on RyR2 using myocardium and cultured cells.Principal Investigator

    • Principal Investigator
      KUREBAYASHI Nagomi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  心臓組織ライブイメージングを利用した動物モデルの不整脈発生メカニズムの包括的解析Principal Investigator

    • Principal Investigator
      呉林 なごみ
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Juntendo University
  •  Study on sudden cardiovascular death in animal model of sleep apnea syndrome

    • Principal Investigator
      YOSHIDA Ken-ichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Pathogenic mechanism of congestive heart failure in a mouse model of dilated cardiomyopathy with brain serotonin dysfunction

    • Principal Investigator
      MORIMOTO Sachio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kyushu University
  •  Regulation of ryanodine receptor channel by interdomain interaction

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Juntendo University
  •  An experimental study for the mechanism of atrial fibrillation and its control by means of optical imaging of cell-to-cell communicationPrincipal Investigator

    • Principal Investigator
      KUREBAYASHI Nagomi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  Molecular mechanisms underlying abnormal functions in RyR2 complex in cardiac hypertrophy/heart failure

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  IDENTIFICATION OF NON-VOLTAGE DEPENDENT CA^<2+> INFLUX PATHWAY IN CARDIAC MUSCLE AND ITS REGULATORY MECHANISM -Analysis by observation of subcellular Ca^<2+> dynamics using evanescent-field fluorescence microscopy-Principal Investigator

    • Principal Investigator
      KUREBAYASHI Nagomi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  TITLE OF PROJECT : Effects of Drugs Used in Heart Failure on Energy Consumption of Loaded and Unloaded Cardiac Muscles.Principal Investigator

    • Principal Investigator
      KUREBAYASHI Kunihiro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  骨格筋スキンドファイバ-における化学的・力学的反応のカップリングの調節機構Principal Investigator

    • Principal Investigator
      国広 なごみ (呉林 なごみ)
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  筋小胞体Ca^<2+>-ATPase蛋白のドメイン間相互作用

    • Principal Investigator
      小川 靖男
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  Increase by drugs in Ca^<2+> sensitivity of myofibrils

    • Principal Investigator
      OGAWA Yasuo
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent Other

  • [Book] 不整脈学2012

    • Author(s)
      呉林 なごみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Book] 不整脈学2012

    • Author(s)
      呉林なごみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Book] "Encyclopedia of Molecular Pharmacology"Ryanodine receptor2008

    • Author(s)
      Murayama T, Kurebayashi N, Ogawa Y
    • Publisher
      Springer,Berlin
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca<sup>2+</sup>Monitoring2023

    • Author(s)
      Takenaka Mai、Kodama Masami、Murayama Takashi、Ishigami-Yuasa Mari、Mori Shuichi、Ishida Ryosuke、Suzuki Junji、Kanemaru Kazunori、Sugihara Masami、Iino Masamitsu、Miura Aya、Nishio Hajime、Morimoto Sachio、Kagechika Hiroyuki、Sakurai Takashi、Kurebayashi Nagomi
    • Journal Title

      Molecular Pharmacology

      Volume: 104 Issue: 6 Pages: 275-286

    • DOI

      10.1124/molpharm.123.000720

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Journal Article] Drug development for the treatment of RyR1-related skeletal muscle diseases2023

    • Author(s)
      Takashi Murayama, Nagomi Kurebayashi, Ryosuke Ishida, Hiroyuki Kagechika
    • Journal Title

      Current Opinion in Pharmacology

      Volume: 69 Pages: 102356-102356

    • DOI

      10.1016/j.coph.2023.102356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15244, KAKENHI-PROJECT-22K06652
  • [Journal Article] A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment2023

    • Author(s)
      Ishida Ryosuke、Kurebayashi Nagomi、Iinuma Hiroto、Zeng Xi、Mori Shuichi、Kodama Masami、Murayama Takashi、Masuno Hiroyuki、Takeda Fumi、Kawahata Masatoshi、Tanatani Aya、Miura Aya、Nishio Hajime、Sakurai Takashi、Kagechika Hiroyuki
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 262 Pages: 115910-115910

    • DOI

      10.1016/j.ejmech.2023.115910

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K15244
  • [Journal Article] Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.2023

    • Author(s)
      Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, Manabe H, Nakau K, Wada T, Kato K, Toyoda F, Yoshida Y, Makita N, Woltjen K, Ohno S, Kurebayashi N, Murayama T, Sakurai T, Horie M, Kimura T.
    • Journal Title

      Circulation: Arrhythmia and Electrophysiology

      Volume: 16 Issue: 3 Pages: 9999-9999

    • DOI

      10.1161/circep.122.011387

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-21K06781, KAKENHI-PROJECT-22K08179, KAKENHI-PROJECT-20K17113, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02920
  • [Journal Article] Involvement of kallikrein‐PAR2‐proinflammatory pathway in severe trastuzumab‐induced cardiotoxicity2022

    • Author(s)
      Sasaki Ritsuko、Kurebayashi Nagomi、Eguchi Hidetaka、Horimoto Yoshiya、Shiga Takahiro、Miyazaki Sakiko、Kashiyama Taku、Akamatsu Wado、Saito Mitsue
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 10 Pages: 3449-3462

    • DOI

      10.1111/cas.15508

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07301, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-19K07105
  • [Journal Article] Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations2022

    • Author(s)
      Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 2821-2821

    • DOI

      10.1038/s41467-022-30429-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02411, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
  • [Journal Article] Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR22022

    • Author(s)
      Kurebayashi Nagomi、Murayama Takashi、Ota Ryosaku、Suzuki Junji、Kanemaru Kazunori、Kobayashi Takuya、Ohno Seiko、Horie Minoru、Iino Masamitsu、Yamashita Fumiyoshi、Sakurai Takashi
    • Journal Title

      Journal of General Physiology

      Volume: 154 Issue: 9

    • DOI

      10.1085/jgp.202112869

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
  • [Journal Article] NRSF- GNAO1 Pathway Contributes to the Regulation of Cardiac Ca 2+ Homeostasis2022

    • Author(s)
      Inazumi Hideaki、Kuwahara Koichiro、Nakagawa Yasuaki、et al.
    • Journal Title

      Circulation Research

      Volume: 130 Issue: 2 Pages: 234-248

    • DOI

      10.1161/circresaha.121.318898

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07297, KAKENHI-PROJECT-19K08580, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-20H03673, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K07299, KAKENHI-PROJECT-21K08126, KAKENHI-PROJECT-20K17077, KAKENHI-PROJECT-22K08099
  • [Journal Article] Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes2022

    • Author(s)
      Tsuboi Yoshitaka、Oyama Kotaro、Kobirumaki-Shimozawa Fuyu、Murayama Takashi、Kurebayashi Nagomi、Tachibana Toshiaki、Manome Yoshinobu、Kikuchi Emi、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、Nishino Ichizo、Mori Shuichi、Ishida Ryosuke、Kagechika Hiroyuki、Suzuki Madoka、Fukuda Norio、Yamazawa Toshiko
    • Journal Title

      Journal of General Physiology

      Volume: 154 Issue: 11

    • DOI

      10.1085/jgp.202213136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06789, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21K19929, KAKENHI-PLANNED-22H05053, KAKENHI-PLANNED-22H05054, KAKENHI-PLANNED-22H05055, KAKENHI-PROJECT-20H03421, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24778, KAKENHI-PROJECT-23K24067
  • [Journal Article] Development of a water-soluble ryanodine receptor 1 inhibitor2022

    • Author(s)
      Ishida Ryosuke、Mori Shuichi、Murayama Takashi、Nakamichi Ayaka、Chai Xikun、Kurebayashi Nagomi、Iinuma Hiroto、Kagechika Hiroyuki
    • Journal Title

      Bioorganic &amp; Medicinal Chemistry

      Volume: 74 Pages: 117027-117027

    • DOI

      10.1016/j.bmc.2022.117027

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K15244, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
  • [Journal Article] Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating2022

    • Author(s)
      Oyama Kotaro、Zeeb Vadim、Yamazawa Toshiko、Kurebayashi Nagomi、Kobirumaki-Shimozawa Fuyu、Murayama Takashi、Oyamada Hideto、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、Nishino Ichizo、Harada Yoshie、Fukuda Norio、Ishiwata Shin’ichi、Suzuki Madoka
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 32

    • DOI

      10.1073/pnas.2201286119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-21K06789, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21K19929, KAKENHI-PLANNED-20H05785, KAKENHI-PLANNED-22H05053, KAKENHI-PLANNED-22H05054, KAKENHI-PLANNED-22H05055, KAKENHI-PROJECT-20H03421, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K23847, KAKENHI-PROJECT-23K24778, KAKENHI-PROJECT-23K24067
  • [Journal Article] A reconstituted depolarization-induced Ca2+ release platform for validation of skeletal muscle disease mutations and drug discovery2022

    • Author(s)
      Murayama Takashi、Kurebayashi Nagomi、Numaga-Tomita Takuro、Kobayashi Takuya、Okazaki Satoru、Yamashiro Kyosuke、Nakada Tsutomu、Mori Shuichi、Ishida Ryosuke、Kagechika Hiroyuki、Yamada Mitsuhiko、Sakurai Takashi
    • Journal Title

      Journal of General Physiology

      Volume: 154 Issue: 12

    • DOI

      10.1085/jgp.202213230

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K06828, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
  • [Journal Article] Therapeutic effects of novel type1 ryanodine receptor inhibitor on skeletal muscle diseases2022

    • Author(s)
      Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、Murayama Takashi
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 157 Issue: 1 Pages: 15-22

    • DOI

      10.1254/fpj.21068

    • NAID

      130008138777

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K11368
  • [Journal Article] The Ryanodine Receptor as a Sensor for Intracellular Environments in Muscles2021

    • Author(s)
      Kobayashi Takuya、Kurebayashi Nagomi、Murayama Takashi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 19 Pages: 10795-10795

    • DOI

      10.3390/ijms221910795

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-19H03404
  • [Journal Article] Differential effects of the formin inhibitor SMIFH2 on contractility and Ca 2+ handling in frog and mouse cardiomyocytes2021

    • Author(s)
      Sakata Koji、Matsuyama Sho、Kurebayashi Nagomi、Hayamizu Kengo、Murayama Takashi、Nakamura Kunihide、Kitamura Kazuo、Morimoto Sachio、Takeya Ryu
    • Journal Title

      Genes to Cells

      Volume: 26 Issue: 8 Pages: 583-595

    • DOI

      10.1111/gtc.12873

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07297, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07355, KAKENHI-PROJECT-19H03404
  • [Journal Article] Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation2021

    • Author(s)
      Itoh Hideki、Murayama Takashi、Kurebayashi Nagomi、Ohno Seiko、Kobayashi Takuya、Fujii Yusuke、Watanabe Masaya、Ogawa Haruo、Anzai Toshihisa、Horie Minoru
    • Journal Title

      Journal of Electrocardiology

      Volume: 69 Pages: 111-118

    • DOI

      10.1016/j.jelectrocard.2021.09.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K08473, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-21H02411
  • [Journal Article] A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke2021

    • Author(s)
      Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、Konishi Masato、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、et al.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 4293-4293

    • DOI

      10.1038/s41467-021-24644-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19K06955, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-19H03404
  • [Journal Article] Purification of Recombinant Wild Type and Mutant Ryanodine Receptors Expressed in HEK293 Cells2021

    • Author(s)
      Hu Yifan、Iyer Kavita、Nayak Ashok、Kurebayashi Nagomi、Murayama Takashi、Samso Montserrat
    • Journal Title

      BIO-PROTOCOL

      Volume: 11 Issue: 15

    • DOI

      10.21769/bioprotoc.4112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
  • [Journal Article] Loss-of-function mutations in cardiac ryanodine receptor channel cause various types of arrhythmias including long QT syndrome2021

    • Author(s)
      Hirose Sayako、Murayama Takashi、Tetsuo Naoyuki、Hoshiai Minako、Kise Hiroaki、Yoshinaga Masao、Aoki Hisaaki、Fukuyama Megumi、Wuriyanghai Yimin、Wada Yuko、Kato Koichi、Makiyama Takeru、Kimura Takeshi、Sakurai Takashi、Horie Minoru、Kurebayashi Nagomi、Ohno Seiko
    • Journal Title

      EP Europace

      Volume: 24 Issue: 3 Pages: 497-510

    • DOI

      10.1093/europace/euab250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08538, KAKENHI-PROJECT-19K08555, KAKENHI-PROJECT-21H02888, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K17113, KAKENHI-PROJECT-19H03404
  • [Journal Article] Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother.2021

    • Author(s)
      Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y
    • Journal Title

      Biomed Pharmacother.

      Volume: 141 Pages: 111800-111800

    • DOI

      10.1016/j.biopha.2021.111800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08866, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-19H03404
  • [Journal Article] Enhanced CICR activity reduces ER Ca2+ level in cells expressing CPVT-linked mutant RyR22021

    • Author(s)
      Kurebayashi Nagomi、Murayama Takashi、Ohta Ryosaku、Suzuki Junji、Kanemaru Kazunori、Ohno Seiko、Horie Minoru、Iino Masamitsu、Yamashita Fumiyoshi、Sakurai Takashi
    • Journal Title

      Biorxiv

      Volume: -

    • DOI

      10.1101/2021.01.16.426980

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Journal Article] Molecular basis for gating and regulation of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations2020

    • Author(s)
      Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
    • Journal Title

      Biorxiv

      Volume: -

    • DOI

      10.1101/2020.11.30.401026

    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Journal Article] A novel RyR1 inhibitor prevents and rescues sudden death in a mouse model of malignant hyperthermia and heat stroke2020

    • Author(s)
      Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、19人省略、Murayama Takashi
    • Journal Title

      Biorxiv

      Volume: -

    • DOI

      10.1101/2020.07.02.185520

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020

    • Author(s)
      Yamazawa Toshiko、Ogawa Haruo、Murayama Takashi、Yamaguchi Maki、Oyamada Hideto、Suzuki Junji、Kurebayashi Nagomi、Kanemaru Kazunori、Oguchi Katsuji、Sakurai Takashi、Iino Masamitsu
    • Journal Title

      The Journal of General Physiology

      Volume: 152 Issue: 1 Pages: 0-0

    • DOI

      10.1085/jgp.201812235

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19H03404
  • [Journal Article] Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a <i>Ryanodine Receptor Type 2</i> Missense Mutation2020

    • Author(s)
      Nozaki Y, Kato Y, Uike K, Yamamura K, Kikuchi M, Yasuda M, Ohno S, Horie M, Murayama T, Kurebayashi N, Horigome H
    • Journal Title

      Circ J

      Volume: 84 Issue: 2 Pages: 226-234

    • DOI

      10.1253/circj.CJ-19-0720

    • NAID

      130007789920

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2020-01-24
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07813, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K19820, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-18K07875
  • [Journal Article] Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies2020

    • Author(s)
      Ogawa Haruo、Kurebayashi Nagomi、Yamazawa Toshiko、Murayama Takashi
    • Journal Title

      Journal of Muscle Research and Cell Motility

      Volume: in press Issue: 2 Pages: 0-0

    • DOI

      10.1007/s10974-020-09575-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-16H04748, KAKENHI-PROJECT-19H03404
  • [Journal Article] RyR2 mutation-linked arrhythmogenic diseases and its therapeutic strategies2020

    • Author(s)
      Kurebayashi Nagomi、Murayama Takashi
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 155 Issue: 4 Pages: 225-229

    • DOI

      10.1254/fpj.20017

    • NAID

      130007867553

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
  • [Journal Article] Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM2020

    • Author(s)
      Iyer Kavita A.、Hu Yifan、Nayak Ashok R.、Kurebayashi Nagomi、Murayama Takashi、Sams? Montserrat
    • Journal Title

      Science Advances

      Volume: 6 Issue: 31 Pages: 0-0

    • DOI

      10.1126/sciadv.abb2964

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
  • [Journal Article] Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay2019

    • Author(s)
      Mori Shuichi、Iinuma Hiroto、Manaka Noriaki、Ishigami-Yuasa Mari、Murayama Takashi、Nishijima Yoshiaki、Sakurai Akiko、Arai Ryota、Kurebayashi Nagomi、Sakurai Takashi、Kagechika Hiroyuki
    • Journal Title

      European Journal of Medicinal Chemistry

      Volume: 179 Pages: 837-848

    • DOI

      10.1016/j.ejmech.2019.06.076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03404
  • [Journal Article] Assays for Modulators of Ryanodine Receptor (RyR)/Ca 2+ Release Channel Activity for Drug Discovery for Skeletal Muscle and Heart Diseases2019

    • Author(s)
      Murayama Takashi、Kurebayashi Nagomi
    • Journal Title

      Current Protocols in Pharmacology

      Volume: 87 Issue: 1 Pages: 0-0

    • DOI

      10.1002/cpph.71

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03404
  • [Journal Article] A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain2019

    • Author(s)
      Uzu Miaki、Nonaka Miki、Miyano Kanako、Sato Hiromi、Kurebayashi Nagomi、Yanagihara Kazuyoshi、Sakurai Takashi、Hisaka Akihiro、Uezono Yasuhito
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 140 Issue: 1 Pages: 109-112

    • DOI

      10.1016/j.jphs.2019.04.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-18K15037
  • [Journal Article] A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca2+ sensitivity2018

    • Author(s)
      Murayama Takashi、Ogawa Haruo、Kurebayashi Nagomi、Ohno Seiko、Horie Minoru、Sakurai Takashi
    • Journal Title

      Communications Biology

      Volume: 1 Issue: 1 Pages: 98-98

    • DOI

      10.1038/s42003-018-0103-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-15K08243
  • [Journal Article] Efficient high-throughput screening by ER Ca2+measurement to identify inhibitors of ryanodine receptor Ca2+-release channels2018

    • Author(s)
      Murayama Takashi、Kurebayashi Nagomi、Ikegami-Yuasa Mari、Mori Shuichi、Suzuki Yukina、Akima Ryunosuke、Ogawa Haruo、Suzuki Junji、Kanemaru Kazunori、Oyamada Hideto、Kiuchi Yuji、Iino Masamitsu、Kagechika Hiroyuki、Sakurai Takashi
    • Journal Title

      Molecular Pharmacology

      Volume: - Issue: 1 Pages: 722-730

    • DOI

      10.1124/mol.117.111468

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08243, KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-25221304
  • [Journal Article] Therapeutic potential of ghrelin and des-acyl ghrelin against chemotherapy-induced cardiotoxicity2017

    • Author(s)
      Nonaka Miki、Kurebayashi Nagomi、Murayama Takashi、Sugihara Masami、Terawaki Kiyoshi、Shiraishi Seiji、Miyano Kanako、Hosoda Hiroshi、Kishida Shosei、Kangawa Kenji、Sakurai Takashi、Uezono Yasuhito
    • Journal Title

      Endocr J

      Volume: 64 Issue: Suppl. Pages: S35-S39

    • DOI

      10.1507/endocrj.64.S35

    • NAID

      130007307943

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507
  • [Journal Article] Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle2016

    • Author(s)
      Hashimoto M, Doi M, Kurebayashi N, Furukawa K, Hirawake-Mogi H, Ohmiya Y, Sakurai T, Mita T, Mikoshiba K, Nara T.
    • Journal Title

      FEBS Open Bio.

      Volume: 6(12) Issue: 12 Pages: 1178-1185

    • DOI

      10.1002/2211-5463.12126

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-16K15268
  • [Journal Article] A type 2 ryanodine receptor variant associated with reduced Ca2+ release and short-coupled torsade de pointe ventricular arrhythmia.2016

    • Author(s)
      Fujii Y, Horie M, et al.
    • Journal Title

      Heart Rhythm

      Volume: 14 Issue: 1 Pages: 98-107

    • DOI

      10.1016/j.hrthm.2016.10.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-25460406, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-15K09689
  • [Journal Article] Genotype-phenotype correlations of malignant hyperthermia and central core disease mutations in the central region of the RYR1 channel.2016

    • Author(s)
      Murayama, T., Kurebayashi, N., Ogawa, H., Yamazawa, T., Oyamada, H., Suzuki, J., Kanemaru, K., Oguchi, K., Iino, M. and Sakurai, T.
    • Journal Title

      Hum Mutat.

      Volume: 37 Issue: 11 Pages: 1231-1241

    • DOI

      10.1002/humu.23072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H04748
  • [Journal Article] Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity.2016

    • Author(s)
      Uehara A, Horie M, et al.
    • Journal Title

      Journal of General Physiology

      Volume: 149 Issue: 2 Pages: 199-218

    • DOI

      10.1085/jgp.201611624

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-26460305, KAKENHI-PROJECT-16K08507
  • [Journal Article] Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.2015

    • Author(s)
      Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0130606-e0130606

    • DOI

      10.1371/journal.pone.0130606

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243, KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25460303
  • [Journal Article] A dominant negative form of inositol 1,4,5-trisphosphate receptor induces metacyclogenesis and increases mitochondrial density in Trypanosoma cruzi.2015

    • Author(s)
      Hashimoto M, Nara T, Enomoto M, Kurebayashi N, Yoshida M, Sakurai T, Mita T, Mikoshiba K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 466 Issue: 3 Pages: 475-480

    • DOI

      10.1016/j.bbrc.2015.09.053

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-25670205, KAKENHI-PROJECT-24390102
  • [Journal Article] キーワード解説:カルシウム・膜電位イメージング2014

    • Author(s)
      呉林なごみ
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 45-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Journal Article] Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model2014

    • Author(s)
      Sugihara M, Odagiri F, Suzuki T, Murayama T, Nakazato Y, Unuma K, Yoshida K, Daida H, Sakurai T, Morimoto S, Kurebayashi N.
    • Journal Title

      PLoS One

      Volume: 8(1) Issue: 1 Pages: e55514-e55514

    • DOI

      10.1371/journal.pone.0055514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249038, KAKENHI-PROJECT-23300145, KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24590331, KAKENHI-PROJECT-24790639, KAKENHI-PUBLICLY-25136718, KAKENHI-PUBLICLY-23136514
  • [Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014

    • Author(s)
      Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
    • Journal Title

      J Clin Invest,

      Volume: 124 Issue: 4 Pages: 1598-1607

    • DOI

      10.1172/jci67621

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22110007, KAKENHI-PROJECT-24501325, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25670721, KAKENHI-PROJECT-221S0001
  • [Journal Article] キーワード解説:カルシウム・膜電位イメージング.2014

    • Author(s)
      呉林なごみ
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 45-46

    • Open Access
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Journal Article] Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.2014

    • Author(s)
      Odagiri, F., H. Inoue, M. Sugihara, T. Suzuki, T. Murayama, T. Shioya, M. Konishi, Y. Nakazato, H. Daida, T. Sakurai, S. Morimoto, N. Kurebayashi
    • Journal Title

      PLoS One

      Volume: 9 Issue: 7 Pages: e101838-e101838

    • DOI

      10.1371/journal.pone.0101838

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718
  • [Journal Article] キーワード解説:カルシウム・膜電位イメージング2014

    • Author(s)
      呉林なごみ
    • Journal Title

      日本薬理学雑誌.

      Volume: 143 Pages: 45-46

    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Journal Article] キーワード解説:カルシウム・膜電位イメージング2014

    • Author(s)
      呉林なごみ
    • Journal Title

      日本薬理学雑誌

      Volume: 143 Pages: 45-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Journal Article] Inositol 1,4,5-Trisphosphate receptor regulates replication, differentiation, infectivity, and virulence of the parasitic protist Trypanosoma cruzi2013

    • Author(s)
      Hashimoto M
    • Journal Title

      Mol Microbiology

      Volume: 87(6) Issue: 6 Pages: 1133-50

    • DOI

      10.1111/mmi.12155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-22310158, KAKENHI-PROJECT-23402046, KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-24590331, KAKENHI-PROJECT-25221002, KAKENHI-PUBLICLY-23136514
  • [Journal Article] 筋小胞体のCa2+放出機構の最近の進歩2012

    • Author(s)
      呉林なごみ
    • Journal Title

      生体の科学

      Volume: 63 Pages: 374-375

    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Journal Article] 筋小胞体のCa2+放出機構の最近の進歩2012

    • Author(s)
      呉林なごみ, 村山尚
    • Journal Title

      生体の科学

      Volume: 63 Pages: 374-375

    • Data Source
      KAKENHI-PROJECT-24590331
  • [Journal Article] Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy2012

    • Author(s)
      Suzuki T, Shioya T, Murayama T, Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H, Morimoto S, Kurebayashi N
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 4 Pages: e35353-e35353

    • DOI

      10.1371/journal.pone.0035353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-23136514
  • [Journal Article] Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy2012

    • Author(s)
      Suzuki T, Shioya T, Murayama T,Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H, Morimoto S, Kurebayashi N
    • Journal Title

      PLoS ONE

      Volume: 7(4)

    • Data Source
      KAKENHI-PROJECT-23300145
  • [Journal Article] Two ryanodine receptor isoforms in nonmammalian vertebrate skeletal muscle : Possible roles in excitation-contraction coupling and other processes2011

    • Author(s)
      Murayama T, Kurebayashi N
    • Journal Title

      Prog Biophys Mol Biol

      Volume: 105 Pages: 134-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Journal Article] Role of amino-terminal half of the S4-S5 linker in type 1 ryanodine receptor(RyR1) channel gating2011

    • Author(s)
      Murayama T, Kurebayashi N, Oba T, Oyamada H, Oguchi K, Sakurai T, Ogawa Y
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 35571-35577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Journal Article] リアノジン受容体2010

    • Author(s)
      呉林なごみ, 村山尚
    • Journal Title

      生体の科学

      Volume: 61 Pages: 444-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Journal Article] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008

    • Author(s)
      Kurebayashi, N.
    • Journal Title

      J Physiol Sci 58

    • NAID

      130007039350

    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Aberrant Cell-to-Cell Coupling in Ca^<2+>-Overloaded Guinea Pig Ventricular Muscles2008

    • Author(s)
      Kurebayashi, Nagomi
    • Journal Title

      Am JPhysiol Cell Physiol

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Aberrant Cell-to-Cell Coupling in Ca^<2+>-Overloaded Guinea Pig Ventricular Muscles2008

    • Author(s)
      Kurebayashi, Nagomi
    • Journal Title

      Am J Physiol:Cell Physiol 294

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Mechanism of Arrhythmogenesis in DCM Medel Mice Associated with Cardiac Troponin T mutation2008

    • Author(s)
      Kurebayashi, N.
    • Journal Title

      Biophys J

    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Aberrant Cell-to-Cell Coupling in Ca^2+-Overloaded Guinea Pig Ventricular Muscles2008

    • Author(s)
      Kurebayashi, N.
    • Journal Title

      Am J Physiol-Cell Physiol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Chracteristics of automatic activity in knock-in mouse model of dilated cardiomyopathy associated with δK210 mutation in cardiac troponin T2007

    • Author(s)
      Nagomi Kurebayashi, A.Chugun, H.Nishizawa, Y.Nakazato, H.Daida, T.Sakurai, S.Morimoto
    • Journal Title

      J. Pharmacological Science 103

      Pages: 74-74

    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Cell-to-Cell propagation of excitation in cardiac muscles determined by Ca2+ and membrane potential imaging2007

    • Author(s)
      N.Kurebayashi, H.Nishizawa, Y.Nakazato
    • Journal Title

      Biophysical J. Abstracts

      Pages: 344-344

    • Data Source
      KAKENHI-PROJECT-18590241
  • [Journal Article] Increased automaticity in ventricular muscle from dilated cardiomyopathy associated with δK210 mutation in cardiac troponin T2007

    • Author(s)
      A.Chugun, H.Nishizawa, Y.Nakazato, H.Daida, T Sakurai, S.Morimoto, N.Kurebayashi
    • Journal Title

      Biophysical J. Abstracts

      Pages: 622-622

    • Data Source
      KAKENHI-PROJECT-18590241
  • [Patent] 2型リアノジン受容体活性抑制剤2022

    • Inventor(s)
      國廣なごみ、村山尚、影近 弘之、森 修一、湯浅 磨里、飯沼 大翔
    • Industrial Property Rights Holder
      順天堂大学、東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Patent] 2型リアノジン受容体活性抑制剤2021

    • Inventor(s)
      國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Holder
      学校法人順天堂、国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Patent] 2型リアノジン受容体活性抑制剤2021

    • Inventor(s)
      国広なごみ、村山 尚、影近弘之、森修 一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Holder
      国広なごみ、村山 尚、影近弘之、森修 一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Patent] 2型リアノジン受容体活性抑制剤2021

    • Inventor(s)
      國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Holder
      学校法人順天堂、国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Patent] 2型リアノジン受容体活性抑制剤2020

    • Inventor(s)
      國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Holder
      学校法人順天堂、国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-020656
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Patent] 2型リアノジン受容体活性抑制剤2020

    • Inventor(s)
      国広なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
    • Industrial Property Rights Holder
      順天堂大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-020656
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Patent] リアノジン受容体阻害薬2018

    • Inventor(s)
      影近弘之、國廣なごみ、村山尚、森修一、湯浅磨里
    • Industrial Property Rights Holder
      学校法人順天堂、国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Patent] リアノジン受容体阻害薬2017

    • Inventor(s)
      村山尚、国広なごみ、影近弘之、森修一、湯浅磨里
    • Industrial Property Rights Holder
      村山尚、国広なごみ、影近弘之、森修一、湯浅磨里
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-205935
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Patent] Ca2+誘発性Ca2+遊離活性抑制剤のスクリーニング方法2016

    • Inventor(s)
      村山尚, 國廣なごみ
    • Industrial Property Rights Holder
      村山尚, 國廣なごみ
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-113147
    • Filing Date
      2016-06-07
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Kurebayashi Nagomi2024

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      第101回 日本生理学会大会, 小倉
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] Effects of a high-affinity and selective RyR2 inhibitor on Ca2+ signals in cardiomyocytes and arrhythmias in CPVT model mice2024

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Biophysical Society Annual Meeting, Philadelphia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] 拡張型心筋症モデルマウスにおける自発運動の頻度と詳細2023

    • Author(s)
      杉原 匡美、柿木 亮、村山 尚、三井田 孝、櫻井 隆、森本 幸生、呉林 なごみ
    • Organizer
      第101回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K11246
  • [Presentation] Effects of a novel RyR2 selective inhibitor on malignant arrhythmias in CPVT model mice2023

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      FAOPS Congress 2023, at daegu 韓国
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] EFFECTS OF VOLUNTARY EXERCISE AND ADMINISTRATION OF RENIN ANGIOTENSIN INHIBITOR ON CARDIAC FUNCTION IN INHERITED DILATED CARDIOMYOPATHY MODEL2023

    • Author(s)
      Masami Sugihara,Ryo Kakigi,Takashi Murayam,Takashi Miida,Takashi Sakura,,Sachio Morimoto,Nagomi Kurebayashi
    • Organizer
      第67回米国生物物理学会
    • Data Source
      KAKENHI-PROJECT-21K11246
  • [Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models2023

    • Author(s)
      Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, U-Inoue Y, Inoue T, Satoru N and Sakurai T
    • Organizer
      第100回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] The effects of microtubule depolymerization on muscular viscoelastic properties.2023

    • Author(s)
      T Kobayashi, N Kurebayashi, Murayama, T Sakurai, M Kaya
    • Organizer
      The 5th Rocky Mountain Muscle Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11368
  • [Presentation] 骨格筋の粘弾性における微小管の役割2023

    • Author(s)
      小林 琢也, 茅 元司,呉林 なごみ, 村山 尚, 櫻井 隆
    • Organizer
      第61回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20K11368
  • [Presentation] The effects of microtubule depolymerization on muscular viscoelastic properties.2023

    • Author(s)
      T Kobayashi, N Kurebayashi, Murayama, T Sakurai, M Kaya
    • Organizer
      The 5th Rocky Mountain Muscle Symposium.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K10692
  • [Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023

    • Author(s)
      Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, Inoue YU, Inoue T, Noguchi S and Sakurai T
    • Organizer
      67th Biophysical Society Anual lMeeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models,2023

    • Author(s)
      Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, U-Inoue Y, Inoue T, Satoru N and Sakurai T
    • Organizer
      第100回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023

    • Author(s)
      Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, Inoue YU, Inoue T, Noguchi S and Sakurai T
    • Organizer
      67th Biophysical Society Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Development of RyR2 inhibitors and verification of their effects on CPVT mouse models2023

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      オーストラリア 生理学会, 日豪合同シンポジウム, メルボルン
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] 骨格筋の粘弾性における微小管の役割2023

    • Author(s)
      小林 琢也, 茅 元司,呉林 なごみ, 村山 尚, 櫻井 隆
    • Organizer
      第61回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-23K10692
  • [Presentation] A novel, high-affinity and selective RyR2 inhibitor effectively suppresses lethal arrhythmias in CPVT mouse models2023

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Gordon Reserach Conference, Muscle: Excitation-contraction coupling
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] 微小管脱重合薬により骨格筋の粘弾性は変化する2022

    • Author(s)
      小林 琢也, 村山 尚, 呉林 なごみ
    • Organizer
      第60回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-20K11368
  • [Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022

    • Author(s)
      村山 尚、呉林 なごみ、冨田(沼賀)拓郎、小林 琢也、中田 勉、石田 良典、森 修一、影近 弘之、山田 充彦、櫻井 隆.
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24067
  • [Presentation] RyR2発現細胞におけるCa2+オシレーションと小胞体Ca2+レベルの調節メカニズム2022

    • Author(s)
      呉林 なごみ, 村山 尚, 太田亮 作, 山下 富義, 鈴木 純二, 金丸 和典, 飯野 正光, 櫻井 隆
    • Organizer
      第99回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 骨格筋脱分極誘発性Ca2+遊離(DICR)再構成系の開発2022

    • Author(s)
      村山 尚、呉林 なごみ、冨田(沼賀)拓郎、小林 琢也、中田 勉、山田 充彦、櫻井 隆
    • Organizer
      第8回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022

    • Author(s)
      村山 尚、呉林 なごみ、冨田(沼賀)拓郎、小林 琢也、中田 勉、石田 良典、森 修一、影近 弘之、山田 充彦、櫻井 隆
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] DIFFERENTIAL IMPACTS OF ARRHYTHMIA-LINKED LOSS-OF-FUNCTION RYR2 MUTATIONS ON CA2+ SIGNALING IN CARDIAC CELLS.2022

    • Author(s)
      Nagomi Kurebayashi, Takashi Murayama, Naoyuki Tetsuo, Sayako Hirose, Minoru Horie, Seiko Ohno, Takashi Sakurai
    • Organizer
      66th Annual Meeting of the Biophysical Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍(CPVT)に対する抗不整脈薬の評価2022

    • Author(s)
      呉林なごみ, 児玉昌美, 村山尚, 杉原匡美, 石井光一郎, 岡部雄太, 村越伸行, 三浦綾, 西尾元, 井上-上野由紀子, 井上高良, 野口悟, 中村衣里, 金井富三夫, 多田昇弘, 櫻井隆
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 拡張型心筋症モデルマウスにおける自発運動とレニン・アンギオテンシン阻害剤投与の比較2022

    • Author(s)
      杉原匡美、柿木 亮、村山 尚、櫻井 隆、三井田 孝、森本幸生、呉林なごみ
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K11246
  • [Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍(CPVT)に対する抗不整脈薬の評価2022

    • Author(s)
      呉林なごみ, 児玉昌美, 村山尚, 杉原匡美, 石井光一郎, 岡部雄太, 村越伸行, 三浦綾, 西尾元, 井上-上野由紀子, 井上高良, 野口悟, 中村衣里, 金井富三夫, 多田昇弘 櫻井隆
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06652
  • [Presentation] 骨格筋脱分極誘発性Ca2+遊離(DICR)再構成系の開発2022

    • Author(s)
      村山 尚、呉林 なごみ、冨田(沼賀)拓郎、小林 琢也、中田 勉、山田 充彦、櫻井 隆
    • Organizer
      第8回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24067
  • [Presentation] 機能喪失型催不整脈性RyR2変異が引き起こす様々なCa2+動態異常2022

    • Author(s)
      呉林 なごみ,村山 尚,哲翁 直之,廣瀬 紗也子,堀江 稔,大野 聖子,櫻井 隆
    • Organizer
      第95回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] CPVTモデルマウスに対するRyR2特異的阻害薬の効果2021

    • Author(s)
      呉林なごみ, 村山尚, 石井光一郎, 小西真人, 杉原匡美, 森修一, 飯沼大翔, 湯浅磨里, 村越伸行, 影近弘之, 櫻井隆
    • Organizer
      第94回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 拡張型心筋症モデルマウスにおける自発運動の効果2021

    • Author(s)
      杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
    • Organizer
      第7回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K11246
  • [Presentation] 新規1型リアノジン受容体(RyR1)阻害剤の結合部位の同定.2021

    • Author(s)
      村山 尚、呉林 なごみ、小林 琢也、小川 治夫、児玉 昌美、森 修一、影近 弘之、櫻井 隆.
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] クライオ電子顕微鏡による心筋型リアノジン受容体loss-of-function変異体の解析2021

    • Author(s)
      小川治夫、小林琢也、包明久、呉林なごみ、斎藤慧、児玉昌美、櫻井隆、吉川雅英、村山尚
    • Organizer
      第94回日本生化学会
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] Search for RyR2 inhibitors and verification of their effects on arrhythmogenic myocardium2021

    • Author(s)
      呉林なごみ
    • Organizer
      第126回日本解剖学会・第98回日本生理学会合同大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 骨格筋脱分極誘発性Ca2+遊離(DICR)再構成系を用いた筋疾患へのアプローチ2021

    • Author(s)
      村山 尚、呉林 なごみ、小林 琢也、岡﨑 諭、山代 暁介、櫻井 隆
    • Organizer
      第7回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] 新規1型リアノジン受容体(RyR1)阻害薬の結合部位の探索.2020

    • Author(s)
      村山 尚、呉林 なごみ、小林 琢也、小川 治夫、児玉 昌美、森 修一、影近 弘之、櫻井 隆.
    • Organizer
      第143回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] Characterization of novel RyR1-selective inhibitors identified by high-throughput screening using ER Ca2+ measurement.2020

    • Author(s)
      Matsukawa H, Murayama T, Kobayashi T, Kurebayashi N, Yamazawa T, Ishigami-Yuasa M, Mori S, Kagechika H, Sakurai T.
    • Organizer
      Biophysical Society 64th Annual Meeting
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] 不整脈疾患におけるRyR2の異常とCICR2020

    • Author(s)
      呉林なごみ
    • Organizer
      第93回 日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Therapeutic effects of a novel RyR1 inhibitor on malignant hyperthermia model mice.2020

    • Author(s)
      Murayama T, Yamazawa T, Kobayashi T, Kurebayashi N, Noguchi S, Nishino N, Mori S, Kagechika H, Lopez JR, Allen PD, Sakurai T.
    • Organizer
      Biophysical Society 64th Annual Meeting
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] 新規RyR1抑制薬の悪性高熱症モデルマウスに対する効果.2020

    • Author(s)
      村山 尚,山澤 徳志子,小林 琢也,呉林 なごみ,野口 悟,西野 一三,森 修一,影近 弘之,Jose R. Lopez,Paul D. Allen,櫻井 隆.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] 小胞体内Ca2+濃度測定により新たに同定されたRyR1選択的阻害剤の性質の検討.2020

    • Author(s)
      松川 紘之、村山 尚、小林 琢也、呉林 なごみ、山澤 徳志子、湯浅 磨里、森 修一、影近 弘之、櫻井 隆.
    • Organizer
      第6回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] Effects of novel RyR2 inhibitors on cardiac myocytes from diseased hearts2020

    • Author(s)
      Nagomi Kurebayashi, Takashi Murayama, Masato Konishi, Shuichi Mori, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Haruo Ogawa, Sachio Morimoto, Takashi Sakurai
    • Organizer
      63th Annual Meeting of the Biophysical Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] 不整脈疾患におけるRyR2の異常とCICR.2020

    • Author(s)
      呉林なごみ
    • Organizer
      第93回 日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Mechanism and therapeutic strategies for arrhythmogenic diseases caused by RyR2 mutations2019

    • Author(s)
      呉林なごみ
    • Organizer
      FAOPS2019(第9回アジア・オセアニア生理学会連合2019年大会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Ryanodine receptor type 2 as a potential target for novel anti-arrhythmic drugs2019

    • Author(s)
      Kurebayashi, N
    • Organizer
      The 71th Annual Meeting of the Korean Physiological Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Mechanism and therapeutic strategies for arrhythmogenic diseases caused by RyR2 mutations2019

    • Author(s)
      Nagomi Kurebayashi
    • Organizer
      9th FAOPS Congress, Symposium25 Calcium signaling in heart disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105
  • [Presentation] Arrhythmias caused by abnormal Ca2+ homeostasis and the treatment strategies2019

    • Author(s)
      呉林なごみ
    • Organizer
      第92回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 悪性高熱症モデルマウスを用いた新規RyR1阻害薬の治療効果の検討.2019

    • Author(s)
      村山 尚、山澤 徳志子、小林 琢也、呉林 なごみ、野口 悟、井上 高良、井上 由紀子、森 修一、飯沼 大翔、間中 紀暁、湯浅 磨里、影近 弘之、西野 一三、櫻井 隆.
    • Organizer
      第5回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] High Throughput Screening of Type 2 Ryanodine Receptor Inhibitors by Monitoring Endoplasmic Reticulum Ca2+2018

    • Author(s)
      Tamura M, Kurebayashi N, Murayama T, Mori S, Ishigami-Yuasa M, Kagechika H, Suzuki J, Kanemaru K, Iino M & Sakurai T.
    • Organizer
      62nd Biophysical Society Annual Meeting (USA)
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 2型リアノジン受容体と心疾患2018

    • Author(s)
      呉林なごみ
    • Organizer
      日本筋学会 第4回学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Ryanodine receptor Ca2+ release channels and cardiac arrhythmia.2018

    • Author(s)
      Kurebayashi, N
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Regulation of Store Ca2+ Level in HEK293 Cells Expressing Type 2 Ryanodine Receptor (RyR2) with CPVT Mutations.2018

    • Author(s)
      Kurebayashi N, Murayama T, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M & Sakurai T.
    • Organizer
      62nd Biophysical Society Annual Meeting (USA)
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Divergent effects of disease-linked mutations in RyR2 on Ca2+ dynamics in cardiac and non-cardiac cells2018

    • Author(s)
      呉林なごみ
    • Organizer
      第95回 日本生理学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Regulation of Store Ca2+ Level in HEK293 Cells Expressing Type 2 Ryanodine Receptor (RyR2) with CPVT Mutations.2018

    • Author(s)
      Kurebayashi N, Murayama T, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M, and Sakurai T.
    • Organizer
      62th Biophysical Society Annual Meeting, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Effects of CICR activity and expression levels of RyR2 on Ca2+ homeostasis in HEK293 cells.2017

    • Author(s)
      Kurebayashi N, Murayama T, Tetsuo N, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M & Sakurai T.
    • Organizer
      Calcium Binding Protein Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 小胞体Ca2+モニタリングによるRyR2抑制薬および活性化薬の探索.2017

    • Author(s)
      呉林なごみ, 村山尚, 田村真衣, 哲翁直之, 湯浅磨里, 森修一, 影近弘之, 鈴木純二, 金丸和典, 飯野正光 & 櫻井隆
    • Organizer
      第27回日本循環薬理学会
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] MODULATION OF CA2+ SIGNALING IN HL-1 CARDIOMYOCYTES BY ARRHYTHMOGENIC RYR2 MUTANTS.2017

    • Author(s)
      Naoyuki Tetsuo, Nagomi Kurebayashi, Takashi Murayama, Takashi Sakurai
    • Organizer
      61th Biophysical Society Annual Meeting
    • Place of Presentation
      New Orleans, LO, USA
    • Year and Date
      2017-02-11
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 疾患変異を有するRyR2が引き起こす細胞内Ca2+動態の変調.2017

    • Author(s)
      呉林なごみ, 尚 村, 哲翁直之, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 黒川洵子, a櫻井隆
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] EFFECTS OF EXPRESSION LEVELS OF WT AND MUTANT RYR2 ON CA2+ HOMEOSTASIS IN HEK CELLS.2017

    • Author(s)
      Kurebayashi N, Murayama T, Suzuki J, Kanemaru K, Iino M, Sakurai T.
    • Organizer
      61th Biophysical Society Annual Meeting
    • Place of Presentation
      New Orleans, LO, USA
    • Year and Date
      2017-02-11
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 心筋由来培養心筋細胞のCa2+シグナリングにおける特発性心室細動(IVF)およびQT延長症候群(LQTS)変異RyR2の効果.2017

    • Author(s)
      哲翁直之, 呉林なごみ, 村山尚, 黒川洵子, 櫻井隆.
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 不整脈原性RyR2変異のCa2+遊離特性―カテコラミン誘発性多型性心室頻拍(CPVT)変異と特発性心室細動(I-VF)変異の比較―2016

    • Author(s)
      呉林なごみ, 村山尚, 太田亮作, 山下冨義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] Characterization of ca2+-induced ca2+ release via ryr2 carrying arrhythmogenic mutations2016

    • Author(s)
      Kurebayashi N, Murayama T, Suzuki J, Kanemaru K, Iino M, Sakurai T.
    • Organizer
      60th Biophysical Society Annual Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2016-02-29
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 心室性不整脈誘発性RyR2変異体の疾患別Ca2+遊離特性.2016

    • Author(s)
      呉林なごみ, 村山尚, 太田亮作, 山下冨義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 2型リアノジン受容体の不整脈原性変異はCICR活性とCa2+ 動態にどのような影響を及ぼすか?2015

    • Author(s)
      呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
    • Organizer
      第88回 日本薬理学会年会.
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] 拡張型心筋症におけるアンジオテンシン受容体阻害薬(ARB)感受性および非感受性リモデリング.2015

    • Author(s)
      呉林なごみ.
    • Organizer
      第92回 日本生理学会大会.
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-24
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] 2型リアノジン受容体の不整脈原性変異はCICR活性とCa2+ 動態にどのような影響を及ぼすか?2015

    • Author(s)
      呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆
    • Organizer
      第88回 日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015

    • Author(s)
      Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai.
    • Organizer
      Biophysical society, 59th Annual Meeting.
    • Place of Presentation
      ボルチモア アメリカ合衆国
    • Year and Date
      2015-02-11
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] Contribution of Calcium-Induced Calcium Release to Calcium Homeostasis in Cells Expressing RyR2 with Disease-Associated Mutations,.2015

    • Author(s)
      Kurebayashi N.
    • Organizer
      Gordon Research Conference, Muscle: Excitation-contraction coupling
    • Place of Presentation
      Sunday River, ME, USA
    • Year and Date
      2015-05-31
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08243
  • [Presentation] 2型リアノジン受容体の不整脈原性変異はCICR活性とCa2+動態にどのような影響を及ぼすか?2015

    • Author(s)
      呉林なごみ, 村山 尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井 隆
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] Effects of MH and CCD mutations in the central region on RyR1 channels.2015

    • Author(s)
      Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, and Takashi Sakurai
    • Organizer
      Biophysical Society 59th Annual Meeting
    • Place of Presentation
      ボルチモア、アメリカ合衆国
    • Year and Date
      2015-02-09
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 1型リアノジン受容体チャネルに対する中央領域疾患変異の効果2015

    • Author(s)
      村山 尚、呉林なごみ、山澤徳志子、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井 隆
    • Organizer
      第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-22
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015

    • Author(s)
      Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai
    • Organizer
      Biophysical society, 59th Annual Meeting
    • Place of Presentation
      Baltimore
    • Year and Date
      2015-02-11
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015

    • Author(s)
      Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai
    • Organizer
      Biophysical society, 59th Annual Meeting
    • Place of Presentation
      ボルチモア、アメリカ合衆国
    • Year and Date
      2015-02-11
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 1型リアノジン受容体チャネル活性に対する中央領域疾患変異の効果2015

    • Author(s)
      村山 尚、呉林なごみ、山澤徳志子、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井 隆
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] Effects of MH and CCD mutations in the central region on RyR1 channels.2015

    • Author(s)
      Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, and Takashi Sakurai
    • Organizer
      Biophysical Society 59th Annual Meeting
    • Place of Presentation
      Baltimore
    • Year and Date
      2015-02-09
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] Divergent effects of disease associated mutations on type 2 ryanodine receptor channel.2014

    • Author(s)
      Kurebayashi, N Murayama, T Uehara, A Yasukochi, M Sakura,i T
    • Organizer
      58th Biophysical Society Annual Meeting
    • Place of Presentation
      サンフランシスコ、米国
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 拡張型心筋症における構造的リモデリングと電気的リモデリングの関係.2014

    • Author(s)
      呉林なごみ, 小田切史徳, 井上華, 杉原匡美, 村山尚, 木森義隆, 小西真人, 森本幸生, 櫻井隆.
    • Organizer
      第130回 日本薬理学会関東部会.
    • Place of Presentation
      星薬科大学(東京)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited dilated cardiomyopathy (DCM) model mice2014

    • Author(s)
      Nagomi Kurebayashi Fuminori Odagiria Hana Inouec Masami Sugiharaa Takeshi Suzukia Takashi Murayama Masato Konishi Yuji Nakazato Hiroyuki Daida Takashi Sakurai Sachio Morimoto
    • Organizer
      17th World Congress of Pharmacology
    • Place of Presentation
      ケープタウン、南アフリカ共和国
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited dilated cardiomyopathy (DCM) model mice.2014

    • Author(s)
      Kurebayashi, N., F. Odagiri, H. Inoue, M. Sugihara, T. Suzuki, T. Murayama, M. Konishi, Y. Nakazato, H. Daida, T. Sakurai, S. Morimoto.
    • Organizer
      17th World Congress of Pharmacology.
    • Place of Presentation
      南アフリカ ケープタウン
    • Year and Date
      2014-07-15
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] 不整脈原性2型リアノジン受容体のCICR特性2014

    • Author(s)
      呉林なごみ 村山尚 鈴木純二 金丸和典 飯野正光 櫻井隆
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited DCM model mice2014

    • Author(s)
      Nagomi Kurebayashi, Fiminori Odagiri, Hana Inoue, Masami Sugihara, Takeshi Suzuki, Takashi Murayama, Takao Shioya, Masato Konishi, Yuji Nakazato, Hiroyuki Daida, Takashi Sakurai, Sachio Morimoto,
    • Organizer
      17th World Congress of Pharmacology
    • Place of Presentation
      ケープタウン、南アフリカ共和国
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 心筋型リアノジン受容体(RyR2)不整脈原性変異のCa2+ 動態とCICR活性に対する効果2014

    • Author(s)
      呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆
    • Organizer
      第24回 日本循環薬理学会
    • Place of Presentation
      山形テルサ、山形市
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 心室性不整脈を誘発する2型リアノジン受容体変異体のCa2+遊離の特性2014

    • Author(s)
      呉林なごみ 村山尚 鈴木純二 金丸和典 飯野正光 櫻井隆
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 不整脈原性2型リアノジン受容体のCICR特性2014

    • Author(s)
      呉林なごみ 村山尚 鈴木純二 金丸和典 飯野正光 櫻井隆
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] 心室性不整脈を誘発する2型リアノジン受容体変異体のCa2+遊離の特性2014

    • Author(s)
      呉林なごみ 村山尚 鈴木純二 金丸和典 飯野正光 櫻井隆
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] Divergent effects of disease associated mutations on type 2 ryanodine receptor channel.2014

    • Author(s)
      Kurebayashi, N Murayama, T Uehara, A Yasukochi, M Sakura,i T
    • Organizer
      58th Biophysical Society Annual Meeting
    • Place of Presentation
      サンフランシスコ、米国
    • Data Source
      KAKENHI-PUBLICLY-25136718
  • [Presentation] 拡張型心筋症モデルマウス心臓の電気的リモデリングに対するカンデサルタンの効果2013

    • Author(s)
      呉林なごみ, 小田切史徳, 杉原匡美, 鈴木剛, 井上華, 村山尚, 塩谷孝雄, 小西真人, 中里祐二, 代田浩之, 櫻井隆, 森本幸生
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 遺伝性拡張型心筋症における無症候期、突然死危険期、破綻期と、これらを左右する因子2013

    • Author(s)
      呉林なごみ
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京 船堀
    • Year and Date
      2013-03-27
    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Presentation] FFECTS OF ANGIOTENSIN II RECEPTOR BLOCKER ON THE PROGRESSION OF ELECTRICAL REMODELING IN HEARTS OF INHERITED DCM MODEL MICE.2013

    • Author(s)
      Odagiri F, Inoue H, Sugihara M, Suzuki T, Murayama T, Shioya T, Konishi M, Nakazato Y, Daida H, Sakurai T, Morimoto S, Kurebayashi N
    • Organizer
      57th Biophysical Society Annual Meeting Philadelphia
    • Place of Presentation
      フィラデルフィア
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 遺伝性拡張型心筋症における無症候期、突然死危険期、破綻期と、これらを左右する因子2013

    • Author(s)
      呉林なごみ
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京 船堀
    • Data Source
      KAKENHI-PROJECT-24590331
  • [Presentation] 拡張型心筋症モデルマウス心臓の電気的リモデリングに対するカンデサルタンの効果2013

    • Author(s)
      呉林なごみ
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Presentation] Regulatory mechanisms of synchronization of action potentials and Ca2+ transients in cardiomyocytes in heart tissues2012

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Presentation] Multistep electrical remodeling and sudden death precede heart failure in inherited dilated cardiomyopathy2012

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      56th Biophysical Society Annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-02-27
    • Data Source
      KAKENHI-PUBLICLY-23136514
  • [Presentation] Role of amino-terminal half of the S4-S5 linker in the RyR1 channel gating2012

    • Author(s)
      Murayama T, Kurebayashi N, Oba T, Oyamada H, Oguchi K, Sakurai T, Ogawa Y
    • Organizer
      Biophysical Society 56th Annual Meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2012-02-27
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Presentation] 1型リアノジン受容体S4-S5リンカーはチャネルゲーティングを調節する2012

    • Author(s)
      村山尚、呉林なごみ、大羽利治、小山田英人、小口勝司、小川靖男、櫻井隆
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Presentation] 新規多機能GFPを用いたリアノジン受容体の構造機能解析2009

    • Author(s)
      村山尚, 小林琢也, 樫山拓, 呉林なごみ, 木森義隆, 諸根信弘, 北井敏幸, 高萩隆行, 櫻井隆
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-17
    • Data Source
      KAKENHI-PROJECT-21500383
  • [Presentation] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      J Physiol Sci 58 Suppl. : S178, Japanese Physiological Society
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Mechanism of Arrhythmogenesis in DCM Model Mice Associated with Cardiac Troponin T mutation2008

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Biophysical Society 52nd Annual Meeting
    • Place of Presentation
      Long Beach,CA,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Mechanism of Arrhythmogenesis in DCM Medel Mice Associated with Cardiac Troponin T mutation2008

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Biophys J 303a, Biophysical Society 52nd Annual Meeting
    • Place of Presentation
      Long Beach, CA, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Generation of the GFP-tagged type 1 ryanodine receptor mutants by transposon-based random insertion approach2008

    • Author(s)
      Murayama, T, Kashiyama, T, Oyamada, H, Kobayashi, T, Kurebayashi, N, Sakurai, T
    • Organizer
      Biophysical Society 52nd Annual Meeting
    • Place of Presentation
      Long Beach, CA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Cell-to-cell propagation of excitation in cardiac muscles determined by Ca^<2+> and membrane potential imaging2007

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Biophysical Society 51st Annual Meeting
    • Place of Presentation
      Baltimore,MD,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Role of a cytoplasmic loop between M7b and M8 transmembrane helices of RyR1 in Ca^<2+> channel gating2007

    • Author(s)
      Murayama, T, Oyamada, H, Oba, T, Oguchi, K, Kurebayashi, N
    • Organizer
      Biophysical Society 51st Annual Meeting
    • Place of Presentation
      Baltimore, MD
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Characteristics of automatic activity in knock-in mouse model of dilated cardiomyopathy associated with deltaK210 in cardiac troponin T2007

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      J Pharmacol Science 103 Supplement I : 74P, Japanese Pharmacological Society
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Regulation of intracellular Ca^<2+> by intercellular communication in cardiac muscle2006

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      Muscle:Excitation/Contraction Coupling(Gordon Research Conference)
    • Place of Presentation
      New London,NH,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Regulation of intracellular Ca^<2+> by intercellular communication in cardiac muscle2006

    • Author(s)
      Kurebayashi, Nagomi
    • Organizer
      in Muscle : Excitation / Contraction Coupling(Gordon Research Conference)
    • Place of Presentation
      NH, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Ca^<2+>イメージングと膜電位イメージングによる心筋の興奮伝導遅延の検討2006

    • Author(s)
      呉林 なごみ
    • Organizer
      循環薬理学会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590241
  • [Presentation] Postulated role of interdomain interactions within the type 1 ryanodine receptor in dysfunction of Ca^<2+> release channel in malignant hyperthermia2006

    • Author(s)
      Murayama, T, Oyamada, H, Kurebayashi, N, Oba, T, Hara, H, Wakebe, K, Ikemoto, N, Ogawa, Y
    • Organizer
      Biophysical Society 50th Annual Meeting
    • Place of Presentation
      Salt Laky City, UT
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] C末端悪性高熱変異を有する1型リアノジン受容体チャネルの機能解析

    • Author(s)
      村山 尚、青木良輔、赤塚祐介、呉林なごみ、小山田英人、小口勝司、櫻井 隆
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      船堀
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Presentation] 1型リアノジン受容体チャネルに対する疾患変異の多様な効果

    • Author(s)
      村山 尚、呉林なごみ、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井 隆
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590330
  • []

  • 1.  MURAYAMA Takashi (10230012)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 79 results
  • 2.  Kobayashi Takuya (60468585)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 3.  小川 治夫 (40292726)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 4.  杉原 匡美 (80648163)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 5.  OGAWA Yasuo (50103841)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MORIMOTO Sachio (50202362)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 7.  OBA Toshiharu (50008330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 8.  NAKAZATO Yuji (30266035)
    # of Collaborated Projects: 2 results
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  • 9.  村越 伸行 (80447218)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  茅 元司 (00422098)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 11.  冨田 拓郎 (60705060)
    # of Collaborated Projects: 2 results
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  • 12.  柿木 亮 (70614931)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  MORONE Nobuhiro (50399680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  TAKAHAGI Takayuki (40271069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  UEHARA Akira (60140745)
    # of Collaborated Projects: 1 results
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  • 16.  YOSHIDA Ken-ichi (40166947)
    # of Collaborated Projects: 1 results
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  • 17.  MORIMOTO Keiko (30220081)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  UEYAMA Takashi (50264875)
    # of Collaborated Projects: 1 results
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  • 19.  KUWAHIRA Ichiro (60186567)
    # of Collaborated Projects: 1 results
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  • 20.  SHIRAI Mikiyasu (70162758)
    # of Collaborated Projects: 1 results
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  • 21.  KATAFUCHI Toshihiko (80177401)
    # of Collaborated Projects: 1 results
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  • 22.  TAKE Sachiko (80253425)
    # of Collaborated Projects: 1 results
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  • 23.  SAKAMOTO Kensaku (50240685)
    # of Collaborated Projects: 1 results
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  • 24.  Aonuma Kazutaka (10375488)
    # of Collaborated Projects: 1 results
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  • 25.  原藤 光 (40133334)
    # of Collaborated Projects: 1 results
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  • 26.  中郡 昭人 (50236824)
    # of Collaborated Projects: 1 results
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  • 27.  入鹿山 容子 (90312834)
    # of Collaborated Projects: 1 results
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  • 28.  柳沢 正史 (20202369)
    # of Collaborated Projects: 1 results
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  • 29.  森 修一 (00467630)
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  • 30.  渡邊 大輝 (30823281)
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  • 31.  井上 華 (20390700)
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  • 32.  児玉 昌美 (30512248)
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  • 37.  岡本 瑞穂 (90964148)
    # of Collaborated Projects: 1 results
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  • 38.  YAMASHITA fumiyoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 39.  TO Seikon
    # of Collaborated Projects: 0 results
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  • 40.  INOUE Yukiko
    # of Collaborated Projects: 0 results
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  • 41.  KANEMARU Kazunori
    # of Collaborated Projects: 0 results
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  • 42.  MAKIYAMA Takeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  志賀 孝宏
    # of Collaborated Projects: 0 results
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  • 44.  御子柴 克彦
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    # of Collaborated Products: 1 results
  • 45.  桜井 正樹
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  • 46.  小比類巻 生
    # of Collaborated Projects: 0 results
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  • 47.  堀江 稔
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  • 48.  小山田 英人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  小口 勝司
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    # of Collaborated Products: 1 results
  • 50.  飯野 正光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  宮野 加奈子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  上園 保仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  山口 啓介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  井関 雅子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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