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Kido Hiroshi  木戸 博

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KIDO Hiroshi  木戸 博

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Researcher Number 50144978
Other IDs
External Links
Affiliation (Current) 2025: 徳島大学, 先端酵素学研究所, 特任教授
Affiliation (based on the past Project Information) *help 2024: 徳島大学, 先端酵素学研究所, 特任教授
2016 – 2018: 徳島大学, 先端酵素学研究所(デザイン), 特任教授
2013 – 2015: 徳島大学, 疾患酵素学研究センター, 特任教授
2007 – 2012: The University of Tokushima, 疾患酵素学研究センター, 教授
2006: 徳島大学, 学内共同利用施設等, 教授 … More
1997 – 2006: 徳島大学, 分子酵素学研究センター, 教授
2002: Tokushima Univ, Institute for Enzyme Research, Professor, 分子酵素化学研究センター, 教授
2002: 徳島大学, 分子酵素科学研究センター, 教授
1999: The University of Tokushima, Institute for Enzyme Research, Division of Enzyme Chemistry, Professor, 分子酵素科学研究センター, 教授
1993 – 1997: 徳島大学, 酵素科学研究センター, 教授
1996: 徳島大学, 酵素研究センター, 教授
1995: 徳島大学, 酸素科学研究センター, 教授
1993: 徳島大学, 酸素科学研究センター, 教授
1989 – 1992: 徳島大学, 酵素科学研究センター, 助教授
1990: 徳島大学酵素科学研究センター, 助教授
1988: The Univ. of Tokushima, The Inst. for Enzyme Res. Div. of Enzyme Chem., Assistant Professor, 酵素化学部門, 助手
1988: Div. of Enzyme chem., Inst. for Enzyme Res.,Univ. of Tokushima (Assistant Profes, 酸素化学部門, 助手
1987: 徳島大学, 酵素科学研究センター, 助手
1986: 徳島大, 医学部, 助手
1986: 徳島大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / General medical chemistry / Infectious disease medicine / 膠原病・アレルギー・感染症内科学 / Science and Engineering / General internal medicine and related fields / Collagenous pathology/Allergology / Virology / Emergency medicine / Bioorganic chemistry / Biological Sciences / Functional biochemistry … More
Except Principal Investigator
… More Obstetrics and gynecology / Pathological medical chemistry / General pharmacology / Functional biochemistry / Gastroenterology / General medical chemistry / Biological Sciences / Structural biochemistry / Basic Section 08030:Family and consumer sciences, and culture and living-related / 膠原病・アレルギー・感染症内科学 / Metabolomics / Pediatrics / 代謝生物化学 / Biomedical engineering/Biological material science / Infectious disease medicine / Chemical biology Less
Keywords
Principal Investigator
アレルギー / インフルエンザウイルス / プロテアーゼ / 食物アレルギー / IgE / Hsp70 / プラスミン / 分子シャペロン / エンドセリン(1-31) / トリプターゼクララ … More / センダイウイルス / ATP / トリプシン / 多臓器不全 / プロテアソーム / ミニプラスミン / エンドセリン(1-21) / プロテアーゼインヒビター / gp160 / プロセシングプロテアーゼ / エイズ / レトロウイルス / influenza virus / Chymase / 肥満細胞 / 重症化 / インフルエンザ / 代謝障害 / エネルギー代謝 / エンドセリンレセプター / 好酸球 / ケモカイン / エンドセリン / 平滑筋収縮 / ATPase / CD4 / 肺サーファクタント / gp120 / 外膜蛋白前駆体 / 抗原親和性 / IgG2 / IgG1 / 人工栄養 / 母乳栄養 / 湿疹 / クラススイッチ / ATP-ADP exchange reaction / ADP / 19S Cap / Proteasome / Protease / Molecular chaperone / Influenza virus / EIA / キマーゼ / tryptase Clara / 抗ウイルス作用 / アンチロイコプロテアーゼ / 生体防御物質 / bronchial lavage / defensive compounds / protease / anti-leucoprotease inhibitor / pulmonary surfactant / 気道分泌液 / AIDS / Retrovirus / サイトカイン / 血管透過性亢進 / バイオマーカー / 予後判定 / リアルタイム・バイオマーカー / 重症度 / 乳酸 / MMP-9 / サイトカインストーム / 高病原性鳥インフルエンザ / IgA / マイクロアレイ / 新生児診断 / ダイヤモンドライクカーボン / アレルゲン / 蛋白チップ / 好中球 / IL-5 / エオタキシン / プロセシング / 血管内皮細胞 / ヌクレオシド2リン酸キナーゼ / ATP合成 / 14-3-3蛋白質 / キマ-ゼ / ビックエンドセリン / Anti-leukoprotease inhibitor / Kunitz型インヒビター / X蛋白質 / 膜融合 / エイズウイルス / トリプターゼTL_2 / HIV / セリンプロテア-ゼ / プロセシングプロテア-ゼ / 免疫寛容 / 経口免疫寛容 / IgM / 治療薬 / 代謝破綻 / MCP-1 / イムノモジュレーター / ウイルス / 乳酸菌 / マクロライド / イムノモデュレータ / 脂質代謝 / 糖代謝 / ミトコンドリア / 感染症 / 抗原感作 / 予防 / 免疫グロブリンクラススイッチ / IgG2 / IgG1 / IgE / Chymotrypsin inhibitor / Protein kinase C / Degranulation / Histamine / Mast cell / プロティンキナーゼ / ピネタミン / トリプターゼ / キモトリプシンインヒビター / プロテインキナーゼC / 脱顆粒 / ヒスタミン / edema / blood-brain barrier / mini-plasmin encephalopathy / pneumonia / influenza associated / triggering protease for infection / ウイルス増殖 / 血管-脳血管関門 / プロテアーゼ活性化レセプター / 脂肪酸代謝障害 / 血管-脳関門 / 浮腫 / 血液脳関門 / 肺炎 / インフルエンザ脳炎・脳症 / 感染トリガープロテアーゼ / Aggregation of heat-denatured proteins / Refolding / 活性中心 / アンフォールディング / 熱変性凝集塊形成 / リフォールディング / Proteolysis / ATP-binding protein / Intermediate / Nucleoside diphosphate kinase / ヌクレオシド 2リン酸キナーゼ / 蛋白質分解 / ATP結合蛋白質 / 反応中間体 / Alveolar / Airway / Secretory protease / Plasmin / Sendai virus / Trypsin / Tryptase Clare / 分泌型プロデアーゼ / 肺胞 / 気道 / 分泌型プロテアーゼ / Novel endothelin / Processing / muscle contraction / Endothelin / Big endothelin / 平清筋収縮 / エンドセリンレセクター / 血管 / 気管 / エントセリンレセプター / ビックエントセリン / urokinase / elastase / antileukoprotease / miniplasmin / plasmin / processing / エラフィン / ウロキナーゼ / エラスターゼ / human / protase inhibitor / アンチロイコプロテアーゼインヒビター / ヒト / 抗ウイルス物質 / protease inhibitor / Tryptase Clara / ヘムアクルチニン / 感染阻止 / 生体防御 / serine protease / envelope glycoprotein / processing protease / セリンプロテアーゼ / V3 domain / Tryptase / Trypstatin / 感染機序 / デキストラン硫酸 / トリプタ-ゼTL_2 / V3領域 / トリプタ-ゼ / トリプスタチン / 酵素抗体法 / ヒスタミン遊離 / Flu Alarmin / エネルギー代謝障害 / 血管内皮細胞機能障害 / プロテアーゼ阻害剤 / 季節性インフルエンザ / 診断法 / 治療法 / 重症化機序 / 予后判定 / 集中治療室 / 胎内感作 / タンパクチップ / 高病原も生鳥インフルエンザ / MMP-97 / ATP産生 / ミトコンドリア膜電位 / 血液 / 唾液 / 蛋白質 / 食品 / アレルゲンエピトープ / 14-3-3 / ATP分解 / ヌクレオシド二リン酸キナーゼ / アンチプラスミン / 癌浸潤 / マトリックスメタロプロテアーゼ / 癌転移 / エンドセリンアンタゴニスト / 単球 / 顆粒球 / ケモタキシス / 蛋白分解酵素 / Dnak / マトリックス / MT-MMP / メタロプロテアーゼ / 転移 / がん / ATPアーゼ / DnaK蛋白質 / HSP蛋白質 / 血管平滑筋収縮 / カテプシンG / tryptase TL_2 / tryptase clara / 肝細胞 / シャペロン / B型肝炎ウイルス / 相互作用 / セリン性プロテアーゼ / B側肝炎ウイルス / 感染機構 / 膜融合蛋白 / ヘムアググルチニン / Furin / GP160 / CD26 / V3ループ / セリンブロテアーゼ / 錐体神経細胞 / クロマフィン細胞 / クニッツ型インヒビタ- / βー蛋白質前駆体 / アルツハイマ- / 熱ショック蛋白HSP-90 / H-7 / スフィンゴシン / プロテインキナ-ゼC / レセプタ- / グルココルチコイドホルモン … More
Except Principal Investigator
プロテアーゼ / 分子シャペロン / プロテアソーム / EGF / トリプスタチン / Hsp70 / AP-1 / Endothelin-1(1-31) / 抗精子抗体 / ジアシールグリセリド / シュードウリジン / 増強物質 / グルココルチコイド / インフルエンザ脳症 / ICG / 赤外線蛍光内視鏡 / 微小癌 / 細胞増殖 / CD4 / トリプタ-ゼ / gp120 / gene chip / proteasome / ATP-ADP exchange reaction / ADP / ATP / 19S Cap / RT-PCR / JNK / Electron paramagnetic resonance / Reactive oxygen species / MCP-1 / Mesangium cell / Monocyte / ET-1(1-31) / Cathepsin C / Cathepsin J / 14-3-3 protein / Molecular chaperone / 14-3-3蛋白質 / 活性中心 / NDPK / ERK / MAP kinase / antisperm antibody / 1F3 / Proteasome / トリプターゼ / Tryptase / 白血病 / エイズ脳症 / インフルエンザウイルス / 蛋白分解 / 細胞周期 / サイクリン / プロテアゾーム / カテプシン / リソゾーム / V3領域 / エイズ / レトロウイルス / 感染機序 / エイズウイルス / AIDS / 抗原Binding-Avidity / 舌下免疫療法 / 経口免疫療法 / 牛乳アレルギー / Diacylglycerol / Pseudouridine / Enhancers of glucocorticoid actions / Lymphatic leukemia / Glucocorticoid / プロテインキナーゼCの阻害剤 / EGF:シュードウリジン / リンパ性白血病 / Tight Junction / Blood-brain barrier (BBB) / Neuronal cell death / HIV-1-associated dementia (HAD) / タイトジャンクション / 血液脳関門 / 神経細胞死 / fatty acid / mitochondria / OCTN-2 / carnitine / influenza / hypoglycemia / JVS mouse / Gene Chip / OCTN 2 / JVS マウス / 長鎖脂肪酸 / ミトコンドリア / OCTN2 / カルニチン / インフルエンザ / 低血糖症 / JVSマウス / heat-inducible aggregation / unfolding / molecular chaperone / リフォールディング / アンフオールディング / 19SCap / 熱変性凝集塊形成 / アンフォールディング / endometrium / calcitonin / サイトカイン / マウス / 子宮内膜 / カルシトニン / peptide / sperm antigen / DNA vaccine / immunocontraceptive vaccine / 粘膜ワクチン / ペプチド / 精子抗原 / 遺伝子ワクチン / 避妊ワクチン / neutrophil / chemotaxis / p38 MAP kinase / human mesangial cell / monocyte / chemotactic effect / antioxidants / p38MAP kinase / glomerulus / mesangium cell / Nucleotide Substitution / Amino Acid Alteration / Clustering Variable Region / Hepatitis C Virus / Hepatocellular Carcinoma / 遺伝子変異 / HCVコア領域 / HBV / HCV / 肝細胞癌 / Protease / Propeptide / Conplex-type / High-mannose-type / Lysosome / プロ鎖ペプチド / Asn結合型糖鎖 / システイン / リソゾ-ム / 気道 / プロペプチド / コンプレックス型 / ハイマンノース型 / カテプシンC / カテプシンJ / ATP syntase / active site / ATPase / 蛋白質分解酵素 / raf-1 / 化学修飾 / ATPシンターゼ / ATPアーゼ / Plasma concentration / intracellular CaィイD12+ィエD1 / Cultured human mesangial cells / Efferent arteriole / Afferent arteriole / ヒト腎臓組織 / ET-1 / 細胞内カルシウムイオン濃度 / ヒト培養メサンギウム細胞 / 輸出細動脈 / 輸入細動脈 / Human / Mast Cells / ヒト / 肥満細胞 / hormone replacenment therapy / protein disulfide isomerase / progesterone / estrogen / molecular chaperon / uterine cervical gland / immunoglobulin binding factor / プロテイン・ジスルフィド・イソメラーゼ / 性周期 / 子宮剄質 / プロテインジスルフィドイソメラーゼ / 性ステロイドホルモン / ホルモン補充療法 / プロテイン・ジスルフィドイソメラーゼ / プロゲステロン / エストロゲン / 子宮頸管 / イムノグロブリン結合因子 / progression factors in GN / Integrin / monoclonal antibody / 腎炎進展因子 / インテグリン / モノクロナール抗体 / Vital Immunohistochemical staining / Infrared Fluorescenct Endoscopy / Infrared Fluorescence / Fluorescence Marker / Endoscopic Diagnosis / ICG Delivative / 診断 / ICG誘導体 / 蛍光標識物質 / Ornithine Decarboxylase / Calpain / Proteases / Protein Degradation / Proteolysis / バイオモジュレーター / X線解析 / オルニチン脱炭酸酵素 / カルパイン / プロテオリシス / V3 domain / Trypstatin / Retrovirus / 細胞内移行 / 前駆体 / プロセシングプロテアーゼ / プロセシング / γグルタミルトランスペプチダーゼ / 刷子縁膜酵素 / 抗原デリバリー / 生体機能材料 / ワクチン / 粘膜免疫 / 肺サーファクタント / ストレス蛋白質 / 高病原性鳥インフルエンザ / ライ症候群 / Naチャネルブロッカー / Caチャネルブロッカー / ウイルス放出阻害 / ジクロフェナック / 解熱剤 / ウイルス放出障害 / ジクロフェナクナトリウム / バイオモジュレータ / 人工糖脂質 / Gag蛋白質 / アクセサリー蛋白質 / HIV複製 / アポトーシス / Vif / Vpr / フレームシフト / 人工糖脂質被覆リポソーム / Nef / NF-kB / Gag / HIV / がん浸潤 / 情報伝達 / 転移 / インヒビター / 癌 / 細胞外マトリックス / Mos / プロテアーゼインヒビター / プロラアーゼ / 糖鎖構造 / システインプロテアーゼ / カテプシンL / トリプタ-ゼM / トリプタ-ゼTL2 / CD4レセプタ- / HIV-1 / 熱ショック蛋白HSP-90 / H-7 / スフィンゴシン / プロテインキナ-ゼC / レセプタ- / グルココルチコイドホルモン Less
  • Research Projects

    (79 results)
  • Research Products

    (192 results)
  • Co-Researchers

    (84 People)
  •  Randomised controlled trial of oral immunotherapy combined with sublingual immunotherapy and exploration of antigen binding affinity as an evaluation measure.

    • Principal Investigator
      今井 孝成
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Showa University
  •  Allergy research prospect with new paradigm open up by the new sensitive allergen microarrayPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      General internal medicine and related fields
    • Research Institution
      The University of Tokushima
  •  Study on the pathogenesis of severe influenza virus infection associated with cytokine storm and its effective treatment optionsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokushima
  •  Discovery of antigen-specific low affinity IgE in cord blood and the mechanisms of affinity maturation after birth for prevention of allergyPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      The University of Tokushima
  •  Screening of Flu Alarmin biomarkers of severe influenza virus infection and their confirmation in animal modelPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokushima
  •  Pathogenicity of multiple organ failure induced by seasonal and highly pathogenic avian influenza virus infection and its therapeutic optionsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokushima
  •  The application to cancer vaccine of SSF that mimics pulmonary surfactant

    • Principal Investigator
      MIZUNO Dai
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Musashino University
      The University of Tokushima
  •  The analysis of host response determining the severe influenza and HIV infection.

    • Principal Investigator
      YANO mihiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Shiga Prefecture
      The University of Tokushima
  •  Studies on real-time biomarker of illness severity inthe patients of critical illness and development of the diagnosis machinePrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      The University of Tokushima
  •  Development of new therapeutics for a highly pathogenic influenza virus infection by inhibition of virus entry and multiplicationPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Infectious disease medicine
    • Research Institution
      The University of Tokushima
  •  乳幼児食物アレルギーの診断と予防を可能にする臍帯血高感度診断デバイスの開発研究Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      The University of Tokushima
  •  The chemical biology of low side effects compound in anti-fever drugs, which is derived from the analysis about fatal function by diclofenac.

    • Principal Investigator
      YANO Mihiro, YOUSSOUF Cisse
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      The University of Tokushima
  •  食物アレルギーを血液と唾液から総合的に診断する新規ハイスループットデバイスの開発Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      The University of Tokushima
  •  ハイスループット食物アレルゲンエピトープ解析ダイヤモンドコーティングチップの開発Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      The University of Tokushima
  •  The role of anti-apoptotic factor 14-3-3 in HIV-1-associated dementia (HAD) pathology : The implication for the therapy

    • Principal Investigator
      YANO Mihiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      The University of Tokushima
  •  Mechanism of encephalitis after influenza virus infection based on defect of β-oxidation in liver

    • Principal Investigator
      KUWAJIMA Masamichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokushima
  •  The relationship between a molecular chaperone and protease : The discovery of NDP kinase like activity of a chaperone, and degeneration diseases.

    • Principal Investigator
      YANO Mihiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  生体内新規鍵物質エンドセリン(1-31)の生理機能:ケモカイン作用と未梢循環制御Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokushima
  •  高感度赤外線蛍光内視鏡を用いた微小癌診断法の開発

    • Principal Investigator
      伊東 進
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  新規生理活性物質・エンドセリン(1-31)の意外な顆粒球・好酸球ケモカイン作用Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bioorganic chemistry
    • Research Institution
      The University of Tokushima
  •  Molecular chaperone activity of the 20S proteasome : Inhibitory activity of the substrate protein aggregation and unflodase activityPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Development of new influenza virus treatments based an the findings of triggering proteases for influenza virus entry into the cells and on the findings of protease-activating receptorsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  Functional analysis of substrate-aggregation inhibition and unfoldase activities in the 20S proteasome

    • Principal Investigator
      INOUE Masahiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kurume University
  •  新規生理活性物質エンドセリン(1-31)の発見とその意外な新生理機能Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokushima
  •  癌細胞膜上のMMP9前躯体新規活性化機構の発見と癌細胞浸潤機序の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  赤外線蛍光内視鏡を用いた微小癌診断法の開発

    • Principal Investigator
      ITO Susumu
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  ATP依存性立体構造変異蛋白群に内在するシャペロン型NDPK活性の発見と変異機序Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Pathophysiological role of ET-1(1-31) on the inflammatory diseases.

    • Principal Investigator
      TAMAKI Toshiaki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokushima
  •  Development of an immunocontraceptive DNA vaccine using sperm

    • Principal Investigator
      MAEGAWA Masahiko, 鎌田 正晴
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      THE UNIVERSITY OF TOKUSHIMA
  •  The basic study concerning the high pregnancy rate by in vitro fertilization-embryo transfer treatment in infertile women with antisperm antibody

    • Principal Investigator
      MAEGAWA Masahiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      The University of Tokushima
  •  新規生理活性物質エンドセリン(1-31)の発見と新生理機能の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Discovery of chaperone-type nucleoside diphosphate kinase activity in Hsp70 and proteasome and its pathophysiological function in these proteinsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Institute for Enzyme Research, The University of Tokushima
  •  Discovery of chaperone-type nucleoside diphosphate kinase, a novel function of molecular chaperone proteins, and role of the activity in proteolysis

    • Principal Investigator
      YANO Mihiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Institute for Enzyme Research, The University of Tokusahima
  •  The studies on the sugar chain structures of rat cathepsin J (C) and its functions.

    • Principal Investigator
      TOWATARI Takae
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokushima
  •  Mutations of the core gene sequence of HCV from patients with hepatocellular carcinoma in China and Japan

    • Principal Investigator
      ITO Susumu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tokushima
  •  癌転移・浸潤にかかわる膜結合型MMP前駆体活性化酵素の発見と作用機序の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  新しい分子シャペロン蛋白質機能、NDP キナーゼ活性の発見と作用機構の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  Discovery of the potentiating proteases for influenza virus infection and their inhibitors as defensive compoundsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      Institute for Enzyme Research, The University of Tokusahima
  •  Role of newly discovered endothelin-1(1-31) on renal injury

    • Principal Investigator
      TAMAKI Toshiaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokushima
  •  新しい分子シャペロン蛋白機能の発見とこれによる基質との動的相互作用Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Medical use of protease inhibitors for virus infectionPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  Novel bioactive endothelins (1-31) produced by chymase and their physiological functionsPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  Hormonal regulation of production and activation of immunoglobulin binding factor.

    • Principal Investigator
      KAMADA Masaharu
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      The University of Tokushima
  •  Regulation and Physiological Roles of Human Tryptase in the Secretary Granules of Mast Cells

    • Principal Investigator
      SAKAI Kentaro
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokushima
  •  キマ-ゼの形成する新しいエンドセリン誘導体の血管と気管支平滑筋収縮作用の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokushima
  •  Mechanism of Selective Degradation of Proteins

    • Principal Investigator
      SUZUKI Koichi
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
      The University of Tokyo
  •  Development of novel diagnosis method for minutecancer by infrared fluorescence endoscopy using fluorescence-emitting antibody by infrared ray excitation.

    • Principal Investigator
      ITO Susumu
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  IDENTIFICATION OF NEW GLOMERULAR PROGRESSION FACTORS USING MONOCLONAL ANTIBODY

    • Principal Investigator
      KAGAMI Shoji
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The University of Tokushima
  •  B型肝炎ウイルスX蛋白質と結合する肝細胞内プロテアーゼの機能変化と発癌機序の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  細胞増殖の制御とプロテアーゼ

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  エイズの病態と制御に関する基礎研究 柱1.HIVの複製機構

    • Principal Investigator
      足立 昭夫
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  バイオモジュレーターとしてのプロテアーゼ

    • Principal Investigator
      鈴木 紘一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  ウイルスと細胞との膜融合を誘発する細胞性プロテアーゼの発見とその制御因子の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  Virus activation by tryptase and its inhibition in vivoPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokushima
  •  HIVのTリンパ球への結合と膜融合に関与するT細胞内プロテアーゼの作用機序Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  B型肝炎ウイルスX蛋白質と結合する肝細胞内プロテアーゼの機能変化と発癌機序の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  細胞増殖の制御とプロテアーゼ

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  細胞増殖の制御とプロテアーゼ

    • Principal Investigator
      木南 英紀
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  エイズウイルスの感染性と複製に関与するT細胞内プロテアーゼ群の作用機序の解析Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  インフルエンザウイルスの感染性を決定する宿主細胞プロテアーゼの発見と作用機序Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  Isolation of the cellular protease that determines infectious tropism of influenza virus in human and inhibition of the infection by the protease inhibitor from human bronchial lavagePrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Institute for Enzyme Research, The University of Tokushima
  •  Tリンパ球へのエイズウイルス感染におけるトリプシン型ブロテアーゼ群関与の分子機構Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  糖鎖構造をモデルにしたカテプシンLの細胞内選別輸送の分子機構

    • Principal Investigator
      唐渡 孝枝
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  レトロウイルス外膜蛋白活性化プロテア-ゼの発見と、その阻害剤による感染阻止Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Purification of processing protease for retroviral envelope glycoprotein and role of it in the process of retroviral infectionPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  アルツハイマ-病アミロイド前駆蛋白の局在ならびに生物機能Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  A novel membrane-bound serine protease in human T4^+-lymphocyte -possible receptor for HIV gp120-

    • Principal Investigator
      KATUNUMA Nobuhiko
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  An approach for development of new drugs for AIDS which inhibit the novel receptor for AIDS virusPrincipal Investigator

    • Principal Investigator
      KIDO Hiroshi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokushima
  •  グルココルチコイド作用発現におけるプロテインキナ-ゼCの役割Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Institution
      The University of Tokushima
  •  グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Effects of chymase on limited proteolysis and activation of protein kinase on the mechanism of degranulation from mast cellsPrincipal Investigator

    • Principal Investigator
      HIROSHI Kido
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima, The Institute for Enzyme Research, Division of Enzyme Chemistry
  •  Synthesis and large production of glucocorticoid action enhancers and development of new steroid therapy.

    • Principal Investigator
      KATUNUMA Nobuhiko
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Division of Enzyme Chemistry, The Institute for Enzyme Research, The U of Tokushima
  •  肥満細胞のヒスタミン顆粒に局在するキマーゼとトリプターゼの細胞生理的役割Principal Investigator

    • Principal Investigator
      木戸 博
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  γ-グルタミントランスペプチダーゼのProcessing Proteaseの追求

    • Principal Investigator
      松田 佳子
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      The University of Tokushima

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 先天性代謝異常ハンドブック:3章 脂肪酸代謝異常2013

    • Author(s)
      木戸 博
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Book] カルニチンパルミトイルトランスフェラーゼII欠損症2013

    • Author(s)
      木戸 博
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Book] インフルエンザ診療ガイド2012

    • Author(s)
      木戸 博
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Book] インフルエンザの最新知識 Q & A、インフルエンザ重症化の新たな対応策は?2012

    • Author(s)
      木戸 博 他
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ脳症の発症メカニズム2019

    • Author(s)
      木戸 博
    • Journal Title

      呼吸器内科

      Volume: 35 Pages: 81-87

    • NAID

      40021788939

    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Oral vaccination with influenza hemagglutinin combined with human pulmonary surfactant-mimicking synthetic adjuvant SF-10 induces efficient local and systemic immunity compared with nasal and subcutaneous vaccination and provides protective immunity in mice.2019

    • Author(s)
      Kimoto T, Kim H, Sakai S, Takahashi E, Kido H
    • Journal Title

      Vaccine

      Volume: 37 Issue: 4 Pages: 612-622

    • DOI

      10.1016/j.vaccine.2018.12.002

    • NAID

      120007042440

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-17K16267
  • [Journal Article] Trajectories of class-switching-related egg and cow’s milk allergen-specific immunoglobulin isotype formation and its modification by eczema with low- and high-affinity immunoglobulin E during early infancy.2019

    • Author(s)
      Irahara M, Shinahara W, Sugimoto M, Ogawa Y, Shitukawa K, Kubota K, Yang L, Saito H, Kagami S, Arisawa K, Kido H
    • Journal Title

      Immun Inflamm Dis

      Volume: 7 Pages: 74-85

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Journal Article] Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines.2018

    • Author(s)
      Hayashi H, Kubo Y, Izumida M, Takahashi E, Kido H, Sato K, Yamaya M, Nishimura H, Nakayama K, Matsuyama T.
    • Journal Title

      Front Cell Infect Microbiol

      Volume: 8 Pages: 91-91

    • DOI

      10.3389/fcimb.2018.00091

    • NAID

      120006937672

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15319, KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-15K08499
  • [Journal Article] 宿主因子を標的にした新たなインフルエンザ治療の試み2018

    • Author(s)
      千田淳司、木戸博、坂口末廣
    • Journal Title

      BIO Clinica

      Volume: 33 Pages: 256-259

    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Adjuvanting influenza hemagglutinin vaccine with a human pulmonary surfactant-mimicking synthetic compound SF-10 induces local and systemic cell-mediated immunity in mice2018

    • Author(s)
      Kim Hyejin、Kimoto Takashi、Sakai Satoko、Takahashi Etsuhisa、Kido Hiroshi
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 1 Pages: 1-15

    • DOI

      10.1371/journal.pone.0191133

    • NAID

      120006812010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16267, KAKENHI-PROJECT-16H05348
  • [Journal Article] Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus2018

    • Author(s)
      Takahashi Etsuhisa、Indalao Irene L.、Sawabuchi Takako、Mizuno Keiko、Sakai Satoko、Kimoto Takashi、Kim Hyejin、Kido Hiroshi
    • Journal Title

      Comparative Immunology, Microbiology and Infectious Diseases

      Volume: 56 Pages: 6-13

    • DOI

      10.1016/j.cimid.2017.11.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16267, KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-15K09569
  • [Journal Article] CPT-II遺伝子多型とインフルエンザ脳症の関係とは?2018

    • Author(s)
      木戸 博
    • Journal Title

      インフルエンザ診療ガイド 2018-19

      Volume: 1 Pages: 206-209

    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Early aggressive intervention for infantile atopic dermatitis to prevent development of food allergy: a multicenter, investigator-blinded, randomized, parsllel group controlled trial (PACI Study): protocol for a randomized controlled trial.2018

    • Author(s)
      Yamamoto-Hanada K, Kobayashi T, Williams H, Minami M, Abe M, Morita K, Natsume O, Sato M, Iwama M, Miyaji Y, Miyata M, Inagaki S, Tatsuki F, Narita M, Nakayama SF, Kido H, Saito H, Ohya Y
    • Journal Title

      Clin Trans Allergy

      Volume: 8 Issue: 1 Pages: 47-47

    • DOI

      10.1186/s13601-018-0233-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Journal Article] Endogenous genetic risk factor for serious heatstroke: the thermolabile phenotype of carnitine palmitoyltransferase II variant2018

    • Author(s)
      Oda J, Yukioka T, Azuma K, Arai T, Chida J, Kido H
    • Journal Title

      Acute Med Surg

      Volume: 6 Pages: 25-29

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Prion protein protects mice from lethal infection with influenza A viruses2018

    • Author(s)
      Chida Junji、Hara Hideyuki、Yano Masashi、Uchiyama Keiji、Das Nandita Rani、Takahashi Etsuhisa、Miyata Hironori、Tomioka Yukiko、Ito Toshihiro、Kido Hiroshi、Sakaguchi Suehiro
    • Journal Title

      PLOS Pathogens

      Volume: 14 Issue: 5 Pages: e1007049-e1007049

    • DOI

      10.1371/journal.ppat.1007049

    • NAID

      120006524496

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07499, KAKENHI-PUBLICLY-17H05701, KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-16K10029, KAKENHI-PROJECT-17K19661
  • [Journal Article] Oral immunotherapy combined with omalizumab for high-risk cow's milk allergy: a randomized controlled trial2017

    • Author(s)
      Masaya Takahashi, Kazuhiko Soejima, Shoichiro Taniuchi, Yasuko Hatano, Sohsaku Yamanouchi, Hideki Ishikawa, Makoto Irahara, Youhei Sasaki, Hiroshi Kido, Kazunari Kaneko
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1

    • DOI

      10.1038/s41598-017-16730-6

    • NAID

      120006875671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Journal Article] 予防と治療に役立つクラススイッチと抗原親和性を測定する高性能蛋白チップ2017

    • Author(s)
      木戸博
    • Journal Title

      アレルギーの臨床

      Volume: 37 Pages: 248-251

    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Journal Article] Detection of ovomucoid- specific low-affinity IgE in infants and its relationship to eczema.2017

    • Author(s)
      Kawamoto N, Kamemura N, Kido H, Fukao T.
    • Journal Title

      Pediatr Allergy Immunol

      Volume: 印刷中 Issue: 4 Pages: 355-361

    • DOI

      10.1111/pai.12702

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15371, KAKENHI-PROJECT-16K10024
  • [Journal Article] インフルエンザ感染の重症化機序と治療、効果的な経鼻、経口ワクチン開発2017

    • Author(s)
      木戸 博
    • Journal Title

      消化と吸収

      Volume: 39 Pages: 72-77

    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Anti-influenza virus activity of extracts from stems of Jatropha multifida Linn. collected in Myanmar2017

    • Author(s)
      M. Shoji, S. Woo, A. Masuda, N. N. Win, H. Ngwe, E. Takahashi, H. Kido, H. Morita, T. Ito.
    • Journal Title

      BMC Complem Altern Med

      Volume: 17 Issue: 1 Pages: 96-96

    • DOI

      10.1186/s12906-017-1612-8

    • NAID

      120006814109

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05138, KAKENHI-PROJECT-16H05348, KAKENHI-PROJECT-17K08333
  • [Journal Article] Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, placebo-controlled trial.2017

    • Author(s)
      Natsume O, Kabashima S, Nakazato J, Yamamoto-Hanada K, Narita M, Kondo M, Saito M, Kishino A, Takimoto T, Inoue E, Tang J, Kido H, Wong GW, Matsumoto K, Saito H, Ohya Y; PETIT Study Team..
    • Journal Title

      Lancet

      Volume: 389 Issue: 10066 Pages: 276-286

    • DOI

      10.1016/s0140-6736(16)31418-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15371, KAKENHI-PROJECT-16K15515, KAKENHI-PROJECT-26870893
  • [Journal Article] Energy metabolic disorder is a major risk factor in severe influenza virus infection. Proposals for new therapeutic options based on animal model experiments.2016

    • Author(s)
      Kido H, Indalao IL, Kim H, Kimoto T, Sakai S, Takahashi E
    • Journal Title

      Respir Investg

      Volume: 54 Pages: 312-319

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] クラススイッチを基盤に免疫応答をモニターする高性能蛋白チップの臨床応用2016

    • Author(s)
      木戸博、杉本真弓
    • Journal Title

      アレルギー

      Volume: 65 Pages: 764-769

    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Journal Article] Differential response in allergen-specific IgE, IgGs, and IgA levels for predicting outcome of oral immunotherapy.2016

    • Author(s)
      Mayumi Sigimoto, Norio Kamemura, Mizuho Nagao, Makoto Irahara, Shoji Kagami, Takao Fujisawa, and Hiroshi Kido.
    • Journal Title

      Pediat. Allegy Immunol.

      Volume: 27 Issue: 3 Pages: 276-282

    • DOI

      10.1111/pai.12535

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15371, KAKENHI-PROJECT-16K19648
  • [Journal Article] IL-1 beta is a key cytokine which induces trypsin upregulation in influenza virus-cytokine-trypsin cycle2016

    • Author(s)
      Indalao IK, Sawabuchi T, Takahashi E, Kido H.
    • Journal Title

      Arch Virol

      Volume: 162 Issue: 1 Pages: 201-211

    • DOI

      10.1007/s00705-016-3093-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Journal Article] Influenza A virus infection of vascular endothelial cells induces2015

    • Author(s)
      Mineyoshi Hiyoshi, Ilere L. Indalao, Mihiro Yano, Kazuhiko Yamane, Etsuhisa Takahashi, Hiroshi Kido
    • Journal Title

      Arch. Virol.

      Volume: 160 Issue: 1 Pages: 225-234

    • DOI

      10.1007/s00705-014-2270-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-25670466, KAKENHI-PROJECT-26350126
  • [Journal Article] Measurement of allergen-specific secretory IgA in stool of neonates, infants and toddlers by protection against degradation of immunoglobulins and allergens2015

    • Author(s)
      Norio Kamemura, Miwa Takashima, Hideaki Morita, Kenji Matsumoto, Hiroshi Saito, and Hiroshi Kido.
    • Journal Title

      J. Med. Invest.

      Volume: 62 Issue: 3.4 Pages: 137-144

    • DOI

      10.2152/jmi.62.137

    • NAID

      130005099155

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15371, KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15377
  • [Journal Article] Abbreviated Half-Lives and Impaired Fuel Utilization in Carnitine Palmitoyltransferase II Variant Fibroblasts2015

    • Author(s)
      Min Yao, Min Cai, Dengfu Yao, Xi Xu, Rongrong Yang, Yuting Li, Yuanyuan Zhang, Hiroshi Kido, Dengbing Yao
    • Journal Title

      PLoS ONE

      Volume: 10(3) Issue: 3 Pages: e0119936-e0119936

    • DOI

      10.1371/journal.pone.0119936

    • NAID

      120006872349

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-25670466
  • [Journal Article] クラススイッチを基盤に免疫環境と免疫応答をモニターする高性能蛋白チップの臨床応用2015

    • Author(s)
      木戸博、杉本真弓、亀村典生、窪田賢司、鈴木宏一
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 64(5) Pages: 488-491

    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Journal Article] インフルエンザ感染症の予防と治療に関する新展開2015

    • Author(s)
      木戸 博
    • Journal Title

      インフルエンザ

      Volume: 16(2) Pages: 5-6

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Oral administration of Lactobacillus strain S-PT84 enhances anti-influenza virus specific IgG production in plasma after limited doses of ingluenza virus vaccination in mice.2015

    • Author(s)
      Toshihiro Maekawa, Takashi Kimoto, Dai Mizuno, Yuichi Furukawa, Masayuki Ida, Etsuhisa Takahashi, Takayuki Izumo, Yoshiko Ono, Hiroshi Shibata, Hiroshi Kido
    • Journal Title

      J. Vaccine and Immunol.

      Volume: 2(1) Pages: 5-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] ウイルス感染症の重症化メカニズム2014

    • Author(s)
      木戸 博
    • Journal Title

      J. Otolaryngo. Head and Neck Surgery

      Volume: 30(11) Pages: 1540-1544

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70.2014

    • Author(s)
      H Endo, M Yano, Y Okumura, H Kido
    • Journal Title

      Cell Death and Disease

      Volume: 2014 Jan 30;5:e1027 Issue: 1 Pages: 1-10

    • DOI

      10.1038/cddis.2013.550

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591477, KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-24591481, KAKENHI-PROJECT-25670466, KAKENHI-PROJECT-25860787, KAKENHI-PROJECT-26350126
  • [Journal Article] インフルエンザ感染の重症化とインフルエンザ脳症の最新知見2014

    • Author(s)
      木戸 博
    • Journal Title

      室医会報

      Volume: 16 Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染症における粘膜免疫の重要性2014

    • Author(s)
      木戸 博
    • Journal Title

      Annual Review 呼吸器

      Volume: 1 Pages: 24-29

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.2014

    • Author(s)
      Hai-Yan Pan, Hua-Mei Sun, Lu-jing Xue, Min Pan, Yi-Ping Wang, Hiroshi Kido, Jian-Hua Zhu
    • Journal Title

      Am. J. Physical Heart Circ. Physiol.

      Volume: 307(6) Issue: 6 Pages: H922-H932

    • DOI

      10.1152/ajpheart.00076.2014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染の重症化機序、肺炎・脳症の最新知見と治療法の提案2014

    • Author(s)
      木戸 博
    • Journal Title

      都耳鼻会報

      Volume: 143 Pages: 41-46

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] ウイルス感染症の重症化メカニズム2014

    • Author(s)
      木戸 博
    • Journal Title

      J. Otolaryngo. Head and Neck Surgery

      Volume: 30(11) Pages: 1540-1544

    • Data Source
      KAKENHI-PROJECT-25670466
  • [Journal Article] Extraction and quantification of adenosine triphosphate in mammalian tissues and cells.2014

    • Author(s)
      Junji Chida, Hiroshi Kido
    • Journal Title

      Methods Mol. Biol.

      Volume: 1098(1) Pages: 21-32

    • DOI

      10.1007/978-1-62703-718-1_2

    • ISBN
      9781627037174, 9781627037181
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-25461596, KAKENHI-PROJECT-25670466
  • [Journal Article] インフルエンザ脳症とCPT-II熱不安定性遺伝子多型2014

    • Author(s)
      木戸 博
    • Journal Title

      クリニシアン

      Volume: 61(634) Pages: 13-16

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorder and multiorgan failure in severe influenza.2014

    • Author(s)
      Kazuhiro Yamane, Irene L. Indalao, Junji Chida, Yoshikazu Yamamoto, Masaaki Hanawa, Hiroshi Kido
    • Journal Title

      PLoS ONE

      Volume: 9(5) Issue: 5 Pages: e98032-e98032

    • DOI

      10.1371/journal.pone.0098032

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ脳症とCPT-II熱不安定性遺伝子多型2014

    • Author(s)
      木戸 博
    • Journal Title

      クリニシアン

      Volume: 61(634) Pages: 13-16

    • Data Source
      KAKENHI-PROJECT-25670466
  • [Journal Article] インフルエンザ感染におけるマクロライドの粘膜免疫増強効果2014

    • Author(s)
      木戸 博、品原 和加子、高橋 悦久
    • Journal Title

      Respiratory Medical Research

      Volume: 2 (4) Pages: 17-21

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染の重症化とインフルエンザ脳症の最新知見2014

    • Author(s)
      木戸 博
    • Journal Title

      室医会報

      Volume: 16 Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-25670466
  • [Journal Article] Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 702014

    • Author(s)
      H Endo. M Yano. Y Okumura. H Kido
    • Journal Title

      Cell Death and Disease

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] 臨床医のためのクリニカクスタディ「インフルエンザ」2013

    • Author(s)
      木戸 博
    • Journal Title

      スズケンメディカル

      Volume: 16(6) Pages: 3-3

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo.2013

    • Author(s)
      Inoue M
    • Journal Title

      J. Biochem.

      Volume: 153(5) Issue: 5 Pages: 431-439

    • DOI

      10.1093/jb/mvt016

    • NAID

      40019646817

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590500, KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ脳症はここまでわかってきた!2013

    • Author(s)
      木戸 博
    • Journal Title

      プライマリーケアのためのインフルエンザ診療2013-2014

      Volume: 1 Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザにおけるマクロライドに有効性の機序2013

    • Author(s)
      木戸 博
    • Journal Title

      呼吸器内科

      Volume: 24(4) Pages: 384-391

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染の重症化とその対策2013

    • Author(s)
      木戸 博、山根 一彦、高橋 悦久、千田 淳司
    • Journal Title

      大阪府内科医会誌

      Volume: 22(2) Pages: 153-158

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Intranasal influenza vaccination using a new synthetic mucosal adjuvant SF-10 –Induction of potent local and systemic immunity with balanced Th1 and Th2 responses2013

    • Author(s)
      Takashi Kimoto 他
    • Journal Title

      Influenza Other Respir. Viruses

      Volume: 7(6) Issue: 6 Pages: 1218-1226

    • DOI

      10.1111/irv.12124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-24500527
  • [Journal Article] Blood lactate/ATP ratio, as an alarm index and real-time biomarker in critical illness.2013

    • Author(s)
      Junji Chida
    • Journal Title

      PLoS One

      Volume: 8(4) Issue: 4 Pages: e60561-e60561

    • DOI

      10.1371/journal.pone.0060561

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23659846, KAKENHI-PROJECT-23791180, KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-25670466
  • [Journal Article] 3分で頭に入る?!インフルエンザ脳症の発症機序とCPT22013

    • Author(s)
      木戸 博
    • Journal Title

      Pharma Tribune

      Volume: 5(10) Pages: 66-67

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Immunomodulator clarithromycin enhamces mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitor: A retrospective analysis.2013

    • Author(s)
      Wakako Shinahara, Etsuhisa Takahashi, Takako Sawabuchi, Masaru Arai, Nobuo Hirotsu, Yoshio Takasaki, Shizuo Shindo, Kyoko Shibao, Takashi Yokoyama, Kiyoshi Nishikawa, Masahiro Mino, Minako Iwaya, Yuji Yamashita, Satoshi Suzuki, Dai Mizuno, Hiroshi Kido
    • Journal Title

      PLoS ONE

      Volume: 8(7) Issue: 7 Pages: e70060-e70060

    • DOI

      10.1371/journal.pone.0070060

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-24500527
  • [Journal Article] 重症インフルエンザ感染の肺炎・脳症の最新知見と治療提案2013

    • Author(s)
      木戸 博、高橋 悦久、山根 一彦
    • Journal Title

      日本臨床内科医会会誌

      Volume: 27(5) Pages: 578-583

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Anti-influenza activity of C60 fullerene derivatives.2013

    • Author(s)
      Shoji M., Takahashi E., Hatakeyama D., IwaiY.,MoritaY.,Shirayama R.,Echigo N., Kido H., Nakamura S., Mashino T., Okutani T., Kuzuhara T.
    • Journal Title

      PLoS ONE

      Volume: (in press) Issue: 6 Pages: e66337-e66337

    • DOI

      10.1371/journal.pone.0066337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590422, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-25460574, KAKENHI-PROJECT-25670466
  • [Journal Article] 重症インフルエンザ感染の肺炎・脳症の最新知見と治療提案2013

    • Author(s)
      木戸博、高橋悦久、山根一彦
    • Journal Title

      日本臨床内科医会誌

      Volume: 27(5) Pages: 578-583

    • Data Source
      KAKENHI-PROJECT-25670466
  • [Journal Article] インフルエンザの生体防御2013

    • Author(s)
      木戸 博、高橋 悦久、山根 一彦
    • Journal Title

      感染症内科

      Volume: 1(6) Pages: 544-551

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo2013

    • Author(s)
      M Inoue. K Yasuda. H Uemura. N Yasaka. H Inoue. A Schnaufer. M Yano. H Kido. D Kohda. H Doi. T Fukuma. A Tsuji. N Horikoshi
    • Journal Title

      J Biochem

      Volume: 153(5) Pages: 431-439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] Anti-influenza activity of C60 fullerence derivatives.2013

    • Author(s)
      Masaki Shoji, Etsuhisa Takahashi, Dai Hatakeyama, Yuma Iwai, Yuka Morita, Riku Shirayama, Noriko Echigo, Hiroshi Kido, Shigeo Nakamura, Tadahiko Mashino, Takeshi Okutani, Takashi Kuzuhara
    • Journal Title

      PLoS ONE

      Volume: 8(6) Issue: 11

    • DOI

      10.1371/annotation/3e6e3fb0-e52f-4a6d-8ea2-34de4147b64f

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザの生体防御2013

    • Author(s)
      木戸博、高橋悦久、山根一彦
    • Journal Title

      感染症内科

      Volume: 1(6) Pages: 544-551

    • Data Source
      KAKENHI-PROJECT-25670466
  • [Journal Article] インフルエンザの重症化2012

    • Author(s)
      木戸 博 他
    • Journal Title

      臨床と微生物

      Volume: 39(54) Pages: 720-724

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染の重症化機序と予防と治療の最新知見2012

    • Author(s)
      木戸 博 他
    • Journal Title

      大阪府内科医会誌

      Volume: 21(2) Pages: 146-151

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Role of host cellular proteases in the pathogenesis of influenza and influenza -induced multiple organ failure2012

    • Author(s)
      H Kido. Y Okumura. E Takahashi. HY Pan. S Wang. D Yao. M Yao. J Chida J. M Yano
    • Journal Title

      Biochim Biophys Actta

      Volume: 1824(1) Pages: 186-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adult2012

    • Author(s)
      Fujimoto C, Takeda N, Kido H., et al
    • Journal Title

      Influenza Other Respi Viruses

      Volume: Nov;6(6) Issue: 6 Pages: 396-403

    • DOI

      10.1111/j.1750-2659.2011.00330.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061, KAKENHI-PROJECT-23591477, KAKENHI-PROJECT-24249059
  • [Journal Article] 体内酵素が制御するインフルエンザウイルス感染と感染の重症化2012

    • Author(s)
      木戸 博
    • Journal Title

      感染・炎症・免疫

      Volume: 42(2) Pages: 36-44

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] インフルエンザ感染症における粘膜免疫とその制御による治療効果の増強2012

    • Author(s)
      木戸 博 他
    • Journal Title

      新薬と臨床

      Volume: 6112 Pages: 2459-2470

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] An efficient extraction method for quantitation of adenosine triphosphate in mammalian tissues and cells2012

    • Author(s)
      Junji Chida, Kazuhiko Yamane, Tunetomo Takei, and Hiroshi Kido
    • Journal Title

      Anal. Chim. Acta

      Volume: 21(728) Pages: 8-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Journal Article] インフルエンザ脳症の発症機序-CPT2遺伝子多型が解き明かす発症リスク2012

    • Author(s)
      木戸博、千田淳司
    • Journal Title

      医学のあゆみ

      Volume: 241(1) Pages: 23-28

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adults2012

    • Author(s)
      C Fujimoto. N Takeda. A Matsunaga. A Sawada. T Tanaka. T Kimoto. W Shinahara. T Sawabuchi. M Yamaguchi. M Hayama. H Yanagawa. M Yano. H Kido
    • Journal Title

      Influenza Other Respi Viruses

      Volume: 6(6) Pages: 396-403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] マクロライド薬によるインフルエンザ感染時の粘膜免疫増強作用2012

    • Author(s)
      木戸 博 他
    • Journal Title

      臨床と微生物

      Volume: 39 Pages: 331-335

    • Data Source
      KAKENHI-PROJECT-24500527
  • [Journal Article] インフルエンザ脳症の発症機序―CPT2遺伝子多型が解き明かす発症リスク2012

    • Author(s)
      木戸 博 他
    • Journal Title

      医学のあゆみ

      Volume: 241(1) Pages: 23-28

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] マクロライド薬によるインフルエンザ感染時の粘膜免疫増強作用2012

    • Author(s)
      木戸 博 他
    • Journal Title

      臨床と微生物

      Volume: 39(54) Pages: 331-335

    • Data Source
      KAKENHI-PROJECT-24249059
  • [Journal Article] Surfactant protein C is an essential constituent for mucosal adjuvanticity of Surfacten, acting as an antigen delivery vehicle and inducing both local and systemic immunity2011

    • Author(s)
      D Mizuno. T Kimoto. T Takei. A Fukuta. W Shinahara. T Takahashi. M Yano. H Kido
    • Journal Title

      Vaccine

      Volume: 26 Pages: 5368-5679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure2011

    • Author(s)
      Hiroshi kido
    • Journal Title

      Biochemica Biophysica Acta-Proteins and Proteomics

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Bezafibrate upregulates carnitine palmitoyltransferase II expression and promotes mitochondrial energy crisis dissipation in fibroblasts of patients with influenza-associated encephalopathy2011

    • Author(s)
      Yao M, Yao D, Kido H., et al
    • Journal Title

      Mol Genet Metab

      Volume: 104(3) Pages: 265-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Up-regulation of ectopic trypsins in the myocardiumby influenza Avirus infection triggers acute myocarditis2011

    • Author(s)
      H-P Pan, M Yano, H Kido
    • Journal Title

      Cardiovasc Res

      Volume: 89 Pages: 595-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] インフルエンザ重症化と脳症の分子機構2011

    • Author(s)
      矢野仁康, 木戸博
    • Journal Title

      化学療法の領(医薬ジャーナル社)

      Volume: Vol.27.No.12 Pages: 54-60

    • Data Source
      KAKENHI-PROJECT-23591477
  • [Journal Article] Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis.2011

    • Author(s)
      H-Y Pan, H Yamada, J Chida, S Wang , M Yano, M Yao, H Kido.
    • Journal Title

      Cardiovascular Research. 89(3)

      Pages: 595-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Upregulation of ectopic ytypsins in the myocardium by influenza A virus infection triggers acute myocarditis2011

    • Author(s)
      Hai-Yan Pan, Hirotugu Yamada, Junji Chida, Siye Wang, Mihiro Yano, Min Yao, Jianhua Zhu, and Hiroshi Kido
    • Journal Title

      Cardiovasc. Res

      Volume: 89(3) Pages: 595-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Journal Article] Upregulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis2011

    • Author(s)
      Pan HY, Yamada H, Kido H, et al.
    • Journal Title

      Casrdiovasc Res

      Volume: 89(3) Pages: 595-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Attenuation of respiratory immune responses by antiviral neuramirsidase inhibitor treatment and boost of mucosal immunoglobulin A response by co-administration of immunomodulator clarithromycin in paediatric influenza2011

    • Author(s)
      H Kido
    • Journal Title

      Influenza Other Respi Viruses

      Volume: 5(1) Pages: 240-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] インフルエンザ感染の重症化をもたらすウイルスと宿主の相互関連2011

    • Author(s)
      木戸博、奥村裕司, 他
    • Journal Title

      呼吸と循環

      Volume: 59(10) Pages: 973-981

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Effect of inhibitor of Toll-like receptors, protease-activated receptor-2 signaling and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes.2011

    • Author(s)
      H-Y Pan, M Yano, H Kido.
    • Journal Title

      The Journal of Medical Investigation 58,1,2

      Pages: 19-28

    • NAID

      130004465241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] インフルエンザウイルス感染症の重症化メカニズムと治療戦略2011

    • Author(s)
      木戸博、千田淳司、山根一彦
    • Journal Title

      呼吸器病

      Volume: 15(1) Pages: 37-39

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure2011

    • Author(s)
      Kido H, Okumura Y, Takahashi E., et al
    • Journal Title

      Biochim Biophys Acta

      Volume: 1824(1) Issue: 1 Pages: 186-194

    • DOI

      10.1016/j.bbapap.2011.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061, KAKENHI-PROJECT-21500632, KAKENHI-PROJECT-23591477, KAKENHI-PROJECT-23791180
  • [Journal Article] Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS 13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication.2010

    • Author(s)
      Y Okumura, E Takahashi, M Yano, M Ohuchi, T Daidoji, T Nakaya, W Gaten, HD Klenk, H Kido.
    • Journal Title

      Journal of Virology 84,10

      Pages: 5089-5096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] 遺伝子多型が解き明かすインフルエンザ脳症と多臓器不全2010

    • Author(s)
      木戸博、千田淳司, 他
    • Journal Title

      実験医学

      Volume: 28(18) Pages: 2927-2933

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] 粘膜免疫機能とインフルエンザ感染2010

    • Author(s)
      木戸博、水野大, 、木本貴士
    • Journal Title

      小児内科

      Volume: 42(9) Pages: 1541-1545

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus2010

    • Author(s)
      Takahashi E, Kataoka K, Kido H, et al.
    • Journal Title

      Microbes Infect

      Volume: 12(10) Pages: 778-783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] 経鼻ワクチンの開発状況2010

    • Author(s)
      木戸博、水野大、武井恒知
    • Journal Title

      インフルエンザ

      Volume: 11(2) Pages: 184-190

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Influenza Virus-Cytokine-Protease Cycle in the Pathogenesis of Vascular Hyperpermeability in Severe Influenza.2010

    • Author(s)
      S Wang, TQ Le, N Kurihara, J Chida, Y Cisse, M Yano, H Kido.
    • Journal Title

      Journal of Infectious Disease 202,7

      Pages: 991-1001

    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Rat model of influenza-associated encephalopathy (IAE) : studies of electroencephalogram (EEG) in vivo. Neuroscience.2010

    • Author(s)
      Cisse Y, Wang S, Inoue I, Kido H.
    • Journal Title

      Microbes Infect. 165(4),12(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] インフルエンザ脳症の発症原因-ミトコンドリア脂肪酸代謝障害と血管内皮細胞の膜透過性の亢進-2010

    • Author(s)
      木戸博、千田淳司、Cisse Y, 他
    • Journal Title

      最新医学

      Volume: 65(1) Pages: 52-60

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] インフルエンザ感染の重症化機序2010

    • Author(s)
      木戸博、千田淳司
    • Journal Title

      神経感染症

      Volume: 15(1) Pages: 66-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] インフルエンザ感染の重症化、多臓器不全の発症メカニズム2010

    • Author(s)
      木戸博、千田淳司, 他
    • Journal Title

      日本臨床

      Volume: 68(8) Pages: 1565-1573

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.2010

    • Author(s)
      Okumura Y, Takahashi E, Kido H. et al.
    • Journal Title

      J Virol

      Volume: 84(10) Pages: 5089-5096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Mechanisms of matrix metalloproteinase-9 upregulation and tissue destruction in various organs in influenza A virus infection.2010

    • Author(s)
      S Wang, T Quang Le, J Chida, Y Cisse, M Yano, H Kido.
    • Journal Title

      J Med Investigation. 57,1,2

      Pages: 26-34

    • NAID

      130004465198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza2010

    • Author(s)
      Wang S, Le TQ, Kido H, et al.
    • Journal Title

      J Infect Dis

      Volume: 202(7) Pages: 991-1001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] アレルゲン同定法の近未来展望2009

    • Author(s)
      木戸博
    • Journal Title

      アレルギー臨床 29(12)

      Pages: 49-53

    • Data Source
      KAKENHI-PROJECT-21659245
  • [Journal Article] Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.2009

    • Author(s)
      Hiroshi Kido
    • Journal Title

      J.Mol.Genet.Med. 3(1)

      Pages: 165-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Boost of mucosal secretory immunoglobulin A response by clarithromycin in paediatric influenza.2009

    • Author(s)
      Sawabuchi T, Suzuki S, Iwase K, Ito C, Mizuno D, Togari H, Watanabe I, Talukder SR, Chida J, Kido H.
    • Journal Title

      Respirology. 14(8)

      Pages: 1173-1179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.2009

    • Author(s)
      H Kido, Y Okumura, E Takahashi, H-Y Pan, S Wang, T Quang Le, M Yano.
    • Journal Title

      J Mol and Gene Med 3,1

      Pages: 167-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Influenza vaccine with Surfacten, a modified pulmonary surfactant, induces systemic and mucosal immune responses without side effects in minipigs.2009

    • Author(s)
      Nishino M, Mizuno D, Kimoto T, Shinahara W, Fukuta A, Takei T, Sumida K, Kitamura S, Shiota H, Kido H.
    • Journal Title

      Vacctine. 18;27(41)

      Pages: 5620-5627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.2009

    • Author(s)
      Hiroshi Kido
    • Journal Title

      J.Mol.Genet.Med. 3(1)

      Pages: 165-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Journal Article] Boost of mucosal secretory immunoglobilin A response by clarithromycin in paediatric influenza2009

    • Author(s)
      Sawabuchi T, Suzuki S, Kido H, et al.
    • Journal Title

      Respirology

      Volume: 14(8) Pages: 1173-1179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses2009

    • Author(s)
      Kido H, Okumura Y, Takahashi E, et al.
    • Journal Title

      J Mol Genet Med

      Volume: 3(1) Pages: 176-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro2009

    • Author(s)
      Kam YW, Okumura Y, Kido H, et al.
    • Journal Title

      PLoS One

      Volume: 4(11)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] 酵素学からみえてくるインフルエンザ感染とインフルエンザ脳症2009

    • Author(s)
      木戸博
    • Journal Title

      インフルエンザ

      Volume: 10(2) Pages: 101-103

    • Data Source
      KAKENHI-PROJECT-21249061
  • [Journal Article] Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus.

    • Author(s)
      Takahashi E, Kataoka K, Fujii K, Chida J, Mizuno D, Fukui M, Hiro-O Ito, Fujihashi K, Kido H.
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Patent] 熱中症に対する発症感受性や発症耐性の判定方法2012

    • Inventor(s)
      木戸 博
    • Industrial Property Rights Holder
      応用酵素医学研究所株式会社
    • Filing Date
      2012-06-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Patent] 熱中症に対する発症感受性や発症耐性の判定方法2012

    • Inventor(s)
      木戸 博
    • Industrial Property Rights Holder
      徳島大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-06-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Patent] 熱中症2012

    • Inventor(s)
      木戸 博
    • Industrial Property Rights Holder
      応用酵素医学研究所株式会社
    • Industrial Property Number
      2011-147227
    • Filing Date
      2012-07-01
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Patent] 熱中症2012

    • Inventor(s)
      木戸 博
    • Industrial Property Rights Holder
      徳島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2011-147227
    • Filing Date
      2012-07-01
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Patent] 病気の重症度の検査方法2011

    • Inventor(s)
      木戸 博、西村 匡司、千田 淳司
    • Industrial Property Rights Holder
      徳島大学
    • Filing Date
      2011-05-31
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23659846
  • [Patent] 乳幼児のアレルギー発症の予測・アレルギーの像悪、改善の判定法2009

    • Inventor(s)
      木戸博, 鈴木宏一
    • Industrial Property Rights Holder
      徳島大学オリエンタル酵母工業(株式会社)
    • Industrial Property Number
      2009-250098
    • Filing Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21659245
  • [Patent] アレルギー疾患の判定方法2008

    • Inventor(s)
      木戸 博, 鈴木 宏一
    • Industrial Property Rights Holder
      徳島大学
    • Filing Date
      2008-02-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19659253
  • [Patent] アレルギー疾患の判定方法2007

    • Inventor(s)
      木戸博, 鈴木宏一
    • Industrial Property Rights Holder
      徳島大学
    • Industrial Property Number
      2007-061702
    • Filing Date
      2007-03-12
    • Data Source
      KAKENHI-PROJECT-18659293
  • [Presentation] 経皮感作食物アレルギーモデルマウスに対する経口ワクチンの治療効果2018

    • Author(s)
      木本貴士、亀田桂子、堺聡子、松本真輝、高橋悦久、長尾みづほ、藤澤隆夫、木戸博
    • Organizer
      第55回日本小児アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] Different modes of immunoglobulin class-switching from allergen-specific IgG1 to low and high affinity IgE in the development of oral tolerance and food allergy.2018

    • Author(s)
      Kido H, Irahara M, Shinahara W
    • Organizer
      第67回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] 肺サーファクタント由来人工合成SF-10アジュバントは、小腸粘膜の抗原提示細胞への抗原取り込みを増強し、消化管と気道粘膜の抗原特異的抗体産生細胞を誘導する2018

    • Author(s)
      木本 貴士、堺 聡子、亀田 桂子、高橋 悦久、木戸 博
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] インフルエンザ感染モデル動物実験法2018

    • Author(s)
      高橋 悦久、木戸 博
    • Organizer
      第25回マクロライド新作用研究会
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] A型インフルエンザ感染においてマクロライド薬は単球走化性タンパク質(MCP-1)産生を抑制し感染局所の炎症性細胞浸潤を軽減すると共に、長期免疫メモリーを増強する2018

    • Author(s)
      高橋 悦久、澤淵 貴子、木戸 博
    • Organizer
      第25回マクロライド新作用研究会
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] カゼイン経皮感作アレルギーモデルマウスの作成と、アレルゲンの経口負荷アナフィラキシー誘発評価系の確立2018

    • Author(s)
      木本貴士、亀田桂子、堺聡子、松本真輝、高橋悦久、長尾みづほ、藤澤隆夫、木戸博
    • Organizer
      第55回日本小児アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] The interplay between inflammation and FAOD in the pathogenesis of infection associated encephalopathy2018

    • Author(s)
      Kido H
    • Organizer
      International Network for Fatty Acid Oxidation Research and Management
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] Allergen-specific low- and high-affinity IgE production associated with differential immunoglobulin class-switching in the development of pediatric food allergy in early infancy2018

    • Author(s)
      Hiroshi Kido, Makoto Irahara, Wakako Shinahara
    • Organizer
      AAAAI/WAO Joint Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] SF-10 adjuvant derived from pulmonary surfactant enhances incorporation of antigens into intestinal antigen presenting cells and induces antigen specific immunities.2018

    • Author(s)
      Kimoto T, Sakai S, Kameda K, Takahashi E, Kido H
    • Organizer
      第54 回日本肺サーファクタント・界面医学界
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] 新生児血中特異的IgE抗体と乳児期の感作についての検討2017

    • Author(s)
      渋谷紀子、斎藤恵美子、苛原誠、佐々木陽平、木戸博
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] 微量採血によるアレルギーモデル実験動物の経時的抗原特異的抗体価の測定系の確立2017

    • Author(s)
      大野仁詩、品原和加子、高橋悦久、木戸博
    • Organizer
      第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] インフルエンザ感染により発現増加するMMP-9とMCP-1はクラリスロマイシンの経口投与により抑制され、炎症が軽減される2017

    • Author(s)
      高橋悦久、澤淵貴子、木本貴士、堺聡子、木戸博
    • Organizer
      第22回日本病態プロテアーゼ学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] インフルエンザウイルスの感染・増殖性を決定する宿主プロテアーゼの同定と、この研究がもたらした重症化機序の解明と経鼻ワクチン開発2017

    • Author(s)
      木戸博
    • Organizer
      第22回日本病態プロテアーゼ学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] 微量採血による継時的抗原特異的イムノイグロブリンクラススイッチの動物実験モニター法2017

    • Author(s)
      佐々木陽平、大野仁詩、鈴木宏一、木戸博
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] インフルエンザAウイルス感染においてクラリスロマイシン投与によりMMP-9とMCP-1の発現誘導が抑制され、肺と心臓の炎症が軽減される2017

    • Author(s)
      高橋悦久、澤淵貴子、木本貴士、堺聡子、木戸博
    • Organizer
      第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] 乳児期におけるイムノグロブリンクラススイッチの進展と抗原親和性2017

    • Author(s)
      苛原誠、佐々木陽平、品原和加子、杉本真弓、香美祥二、木戸博
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] 生後6ヶ月までの母乳栄養児と人工乳栄養児の抗原摂取量の違いを背景とした湿疹誘発IgEクラススイッチパターンの違い2017

    • Author(s)
      木戸博、苛原誠、品原和加子、杉本真弓、香美祥二
    • Organizer
      第54回日本小児アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] Differential immunoglobulin class switching in the productions of aller-gen-specific low and high affinity IgE in the development of pediatric food allergy2017

    • Author(s)
      Kido H, Irahara M, Sasaki Y.
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] 乳児期の経口免疫寛容と食物アレルギー発症の判定に有用なイムノグロブィンクラススイッチパターンの違いとIgEの高抗原親和性、低親和性IgE2017

    • Author(s)
      木戸博、苛原誠、品原和加子、香美祥二
    • Organizer
      第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19662
  • [Presentation] Trypsin upregulation is mainly affected by IL-1β in influenza-cytokine protease cycle2016

    • Author(s)
      Indalao IK, Sawabuchi T, Takahashi E, Kido H.
    • Organizer
      日本生化学会
    • Place of Presentation
      東北大学 川内キャンパス(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] IL-1 beta; signaling induces trypsin upregulation in influenza virus-cytokine-trypsin cycle in multiple organ failure by infection2016

    • Author(s)
      Indalao IK, Sawabuchi T, Takahashi E, Kido H.
    • Organizer
      Option IX
    • Place of Presentation
      Chicago, Sheraton Grand Chicago, USA
    • Year and Date
      2016-08-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] アレルギーモデルマウスにおける微量検体の継時的抗原特異的IgE測定2016

    • Author(s)
      佐々木陽平、吉田裕亮、品原和加子、多田仁美、鈴木宏一、木戸博
    • Organizer
      日本アレルギー学会
    • Place of Presentation
      東京国際ファーラム(東京都千代田区)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] Trypsin upregulation is mainly affected by IL-1β in influenza-cytokine protease cycle2016

    • Author(s)
      Indalao IK, Sawabuchi T, Takahashi E, Kido H.
    • Organizer
      日本病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Data Source
      KAKENHI-PROJECT-16H05348
  • [Presentation] 0-6ヶ月乳児のアレルゲン特異的抗体価イムノイグロブリンクラススイッチの検討2016

    • Author(s)
      苛原誠、佐々木陽平、品原和加子、杉本真弓、香美祥二、木戸博
    • Organizer
      日本アレルギー学会
    • Place of Presentation
      東京国際ファーラム(東京都千代田区)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] 乳児期の卵白アレルゲン特異的IgE抗体の低から高親和性変化の検討2016

    • Author(s)
      苛原誠、佐々木陽平、品原和加子、杉本真弓、香美祥二、木戸博
    • Organizer
      日本アレルギー学会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] 新生児、乳児便中の抗原特異的SIgAの新測定法2015

    • Author(s)
      亀村典生、森田英明、松本健治、斎藤博久、木戸博
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンス新高輪 「東京都港区」
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] 急速経口免疫療法における抗原特異的IgGおよびIgAと予後に関する検討2015

    • Author(s)
      杉本真弓、亀村典生、長尾みづほ、香美祥二、藤澤隆夫、木戸博
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンス新高輪 「東京都港区」
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] 食物特異的IgGは食物アレルギーの診断に有用か2015

    • Author(s)
      夏目統、樺島重憲、山本貴和子、近藤麻伊、岸野愛、斎藤麻耶子、成田雅美、亀村典生、中里純子、元亜紀、橋本みゆき、小室久子、千葉剛史、稲垣真一郎、須田友子、二村昌樹、野村伊知郎、木戸博、大矢幸弘
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンス新高輪 「東京都港区」
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] クラススイッチを基盤に免疫応答をモニターする高性能タンパクチップの臨床応用2015

    • Author(s)
      木戸博
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンス新高輪 「東京都港区」
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-15K15371
  • [Presentation] インフルエンザ感染の重症化とその予防と治療:恩師と歩んだプロテアーゼの病態代謝研究2014

    • Author(s)
      木戸 博
    • Organizer
      第7回酵素学研究拠点シンポジウム
    • Place of Presentation
      徳島大学藤井節郎記念医科学センター(徳島)
    • Year and Date
      2014-11-14
    • Data Source
      KAKENHI-PROJECT-25670466
  • [Presentation] インフルエンザ感染の重症化とその予防と治療:恩師と歩んだプロテアーゼの病態代謝研究2014

    • Author(s)
      木戸 博
    • Organizer
      第7回酵素学研究拠点シンポジウム
    • Place of Presentation
      徳島大学藤井節郎記念医科学センター(徳島県・徳島市)
    • Year and Date
      2014-11-14
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] Importance of the mucosal immunization in influenza virus infection2013

    • Author(s)
      Hiroshi Kido, Etsuhisa Takahashi
    • Organizer
      The 28th International Congress of Chemotherapy and Infection
    • Place of Presentation
      パシフィコ横浜「神奈川県・横浜市」
    • Year and Date
      2013-06-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ感染による重症化と多臓器不全の代謝改善を基盤とした新たな治療ターゲットとその治療法の開発2013

    • Author(s)
      山根一彦、山本善一、塙雅明、木戸博
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜パシフィコ (神奈川県)
    • Data Source
      KAKENHI-PROJECT-25670466
  • [Presentation] 肺サーファクタントの新たな医学応用の可能性―粘膜アジュバントへの応用とワクチン開発―2013

    • Author(s)
      木戸 博
    • Organizer
      第12回肺サーファクタント分子病態研究会
    • Place of Presentation
      札幌医科大学「北海道・札幌市」
    • Year and Date
      2013-06-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] 重症のインフルエンザによる肺炎・脳症の最新知見と、診断・治療への提案2012

    • Author(s)
      木戸 博
    • Organizer
      第26回日本臨床内科医学会
    • Place of Presentation
      ホテルクレメント徳島・あわぎんホール(徳島県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] ヒト内皮細胞に感染したインフルエンザウイルスは、アドヘレンスジャンクションの崩壊を誘導する2012

    • Author(s)
      日吉峰麗, 矢野仁康、木戸博
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Presentation] 抗インフルエンザ薬の使用によって発動の抑制される獲得免疫系と、これを補正するイムノモジュレーターの有用性2012

    • Author(s)
      木戸 博
    • Organizer
      第60回日本化学療法学会西日本支部総会
    • Place of Presentation
      アクロス福岡(福岡県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] Attenuation of respiratory immune responses by antiviral neuraminidase inhibitor treatment and boost of mucosal immunoglobulin A response by administration of immunomodulator Clarithromycin in pediatric influenza2011

    • Author(s)
      Kido H
    • Organizer
      Options for the Control of Influenza VII
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] Potent mucosal antigen delivery vehicle SF-10, mimicking pulmonary surfactant, for nasal influenza vaccination : safety and efficacy2011

    • Author(s)
      Kido H
    • Organizer
      International Conference & Exhibition on Vaccines & Vaccination.
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] インフルエンザ感染の重症化促進因子、血管内皮細胞の細胞間接着に与えるウイルス感染と解熱剤の障害促進効果の解析2011

    • Author(s)
      日吉峰麗, 矢野仁康、木戸博
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591477
  • [Presentation] Potent Mucosal Antigen Delivery Vehicle SF-10, Mimicking Pulmonary Surfactant, for Nasal Influenza Vaccination : Safety and Efficacy2011

    • Author(s)
      H Kido
    • Organizer
      International Cinference & Exhibition on Vaccines & Vaccination
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] 肺サーファクタントの新たな医学応用の可能性-粘膜アジュバントへの応用とワクチン開発2011

    • Author(s)
      木戸博
    • Organizer
      第47回日本肺サーファクタント・界面医学会
    • Place of Presentation
      徳島大学青藍会館(徳島県)
    • Year and Date
      2011-10-29
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] Attenuation of respiratory immune responses by antiviral neuraminidase inhibitor treatment and boost of mucosal immunoglobulin A response by caadministration of immunomodulator Clarithromycin in pediatric influenza2010

    • Author(s)
      木戸博
    • Organizer
      Options for the Control of Influenza VII
    • Place of Presentation
      Hong Kong SAR, China
    • Year and Date
      2010-09-07
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] インフルエンザ感染に伴う体内代謝の変動と感染重症化の機序、診断マーカーと治療2010

    • Author(s)
      木戸博
    • Organizer
      第58回日本化学療法学会
    • Place of Presentation
      長崎市
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] "Influenza-Cytokine-Protease Cycle" in the pathogenesis of vascular hyperpermeability in severe influenza and its possible treatments2010

    • Author(s)
      木戸博
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] インフルエンザの重症化機序と、その予防と治療2010

    • Author(s)
      木戸博
    • Organizer
      日本薬学会130年会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] Influenza-Cytokine-Protease Cycle in the pathogenesis of vascular hyperpermeability in severe influenza and its possible treatments.2010

    • Author(s)
      H Kido, J Chida, S Wang, H-Y Pan, M Yao.
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会、合同学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] インフルエンザはなぜ怖い-重症化機序における宿主因子のプロテアーゼとエネルギー代謝-2010

    • Author(s)
      木戸博
    • Organizer
      第15回日本病態プロテアーゼ学会
    • Place of Presentation
      大阪府豊中市
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] 抗インフルエンザ薬のタミフル、リレンザの服用で気道粘膜の抗ウイルスIgA抗体の産生は抑制されるが、マクロライドの併用はこれを回復させる2010

    • Author(s)
      木戸博
    • Organizer
      第17回マクロライド新作用研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] 熱ストレスによる腸管上皮細胞間タイトジャンクションの崩壊機構2010

    • Author(s)
      矢野仁康、木戸博
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会、合同学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] Pathogenesis of severe influenza and its prevention and treatments2010

    • Author(s)
      Hiroshi Kido
    • Organizer
      第83回日本薬理学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] Role of the host cellular processing proteases in influenza virus infection.2009

    • Author(s)
      Yuushi Okumura、Hiroshi Kido
    • Organizer
      International Proteolysis Society
    • Place of Presentation
      Gold Coast, Australia
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] イブプロフェンは、Hsp70の発現量を低下させる事で、肺腺癌細胞に対するシスプラチンの抗腫瘍活性を増強する2009

    • Author(s)
      矢野仁康、木戸博
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] Immune responses to nasal vaccination of HA Vaccine with new mucosal adjuvants, pulmonary surfactant medicine Surfacten and its synthetic compound in mice and mini-pigs2009

    • Author(s)
      Kido H
    • Organizer
      Influenza vaccine for the world
    • Place of Presentation
      Canne, France
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] インフルエンザ感染重症化の分子基盤と粘膜局所での感染予防の最前線2009

    • Author(s)
      木戸博、王司嘩、千田淳司、水野大、武井恒知
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] Immune responses to nasal vaccination of HA vaccine with new mucosal adjuvants, pulmonary surfactant medicine Surfacten and its synthetic compound, in mice and mini-pigs2009

    • Author(s)
      Hiroshi Kido
    • Organizer
      Influenza vaccine for the World
    • Place of Presentation
      Canne, France
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PROJECT-21249061
  • [Presentation] 高感度DLCアレルギーチップの開発2009

    • Author(s)
      木戸博
    • Organizer
      国際バイオEXPO
    • Place of Presentation
      東京
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-21659245
  • [Presentation] Ibuprofen Increases Cisplatin-induced Apoptosis in Lung Adenocarcinoma by Suppressing Hsp70.2008

    • Author(s)
      M Yano, H Endo, H Kido
    • Organizer
      第31回日本分子生物学会年会、第81回日本生化学会大会、合同学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20611013
  • [Presentation] 新たなアレルゲン同定検査法の開発(臍帯血のアレルゲン診断を可能にした高感度微量検査法)2008

    • Author(s)
      木戸博
    • Organizer
      第58回日本アレルギー学会秋季大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-19659253
  • [Presentation] インフルエンザ感染の重症化に関する最新知見

    • Author(s)
      木戸 博
    • Organizer
      第45回日本小児感染症学会総会・学術集会
    • Place of Presentation
      札幌コンベンションセンター「北海道・札幌市」
    • Year and Date
      2013-10-26 – 2013-10-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] 勝沼信彦先生と共に歩んだプロテアーゼの病態代謝研究:インフルエンザ感染の重症化とその予防と治療

    • Author(s)
      木戸 博
    • Organizer
      第19回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府・豊中市)
    • Year and Date
      2014-08-08 – 2014-08-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ粘膜ワクチン開発の現状

    • Author(s)
      木戸 博
    • Organizer
      第88回日本感染症学会、第62回日本化学療法学会総会
    • Place of Presentation
      ヒルトン福岡シーホーク(福岡県・福岡市)
    • Year and Date
      2014-06-18 – 2014-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ感染が誘導する体内代謝破綻と感染重症化、小児の脳症

    • Author(s)
      木戸 博
    • Organizer
      第54回日本生化学会中国・四国支部例会
    • Place of Presentation
      徳島大学「徳島県・徳島市」
    • Year and Date
      2013-05-31 – 2013-06-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] 発熱毎に神経障害と筋緊張低下が進行した熱不安定性CPTII変異症例

    • Author(s)
      布井 博幸、澤田 浩武、宇藤山 麻衣子、松山 美静代、木戸 博、高橋 悦久
    • Organizer
      第26回日本神経感染症学会
    • Place of Presentation
      金沢歌劇座(石川県・金沢市)
    • Year and Date
      2014-09-04 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ感染による重症化と多臓器不全の代謝改善を基盤とした新たな治療ターゲットとその治療法の開発

    • Author(s)
      山根 一彦、山本 善一、塙 雅明、木戸 博
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      パシフィコ横浜「神奈川県・横浜市」
    • Year and Date
      2013-10-15 – 2013-10-18
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザウイルスの体内複製を増強するtrypsinの臓器内発現量は「代謝障害―サイトカイン」サイクルの調節下にある:PDK4阻害剤の有効性

    • Author(s)
      Indalao I.L.、山根 一彦、木戸 博
    • Organizer
      第19回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府・豊中市)
    • Year and Date
      2014-08-08 – 2014-08-09
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] バクチオールの抗インフルエンザ活性における標的探索

    • Author(s)
      庄司 正樹、江角 朋之、山本 千尋、高橋 悦久、小西 史朗、木戸 博、葛原 隆
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] Stusies on the differences in host cellular responses by diffetent influenza virus straind and subtypes

    • Author(s)
      Irene Lorinda Indalao, Etsuhisa Takahashi, Hiroshi Kido
    • Organizer
      第54回日本生化学会中国・四国支部例会
    • Place of Presentation
      徳島大学「徳島県・徳島市」
    • Year and Date
      2013-05-31 – 2013-06-01
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] Activation of trypsin and interferon regulation factor contributes to different disease severity during infection of influenza A virus with different pathogenicity

    • Author(s)
      Irene Lorinda Indalao, Etsuhisa Takahashi, Hiroshi Kido
    • Organizer
      第18回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター「大阪府・豊中市」
    • Year and Date
      2013-08-16 – 2013-08-17
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ感染が誘導する体内代謝破綻と感染重症化の機序

    • Author(s)
      木戸 博
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      幕張メッセ「千葉県・千葉市」
    • Year and Date
      2013-12-11 – 2013-12-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] PDK4 inhibitor suppresses cytokine storm and multiple organ failure induced by lethal doses of influenza A virus infection through restoration of energy metabolic disorder.

    • Author(s)
      Irene L. Indalao, Kazuhiko Yamane, Hiroshi Kido
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] PDK4 inhibitor suppresses cytokine storm and multiple organ failure induced by lethal doses of influenza A virus infection through restoration of energy metabolic disorder.

    • Author(s)
      Irene L. Indalao, Kazuhiko Yamane, Hiroshi Kido
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都国際会議場(京都府)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25670466
  • [Presentation] インフルエンザ感染の重症化に関する最新知見―粘膜免疫の重要性―

    • Author(s)
      木戸 博
    • Organizer
      第41回日本臨床免疫学会総会
    • Place of Presentation
      海峡メッセ下関「山口県・下関市」
    • Year and Date
      2013-11-27 – 2013-11-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
  • [Presentation] インフルエンザ治療におけるマクロライドのイムノモジュレーター効果と作用機序

    • Author(s)
      木戸 博
    • Organizer
      第21回マクロライド新作用研究会
    • Place of Presentation
      飯田橋レインボービル(東京都・新宿区)
    • Year and Date
      2014-07-18 – 2014-07-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249059
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  • 83.  葛原 隆
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  • 84.  原 英之
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