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Suzumura Akio  錫村 明生

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錫村 明生  スズムラ アキオ

SUZUMURA Akio  錫村 明生

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Researcher Number 50196896
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 名古屋大学, 環境医学研究所, 教授
2006 – 2007: 名古屋大学, 環境医学研究所, 教授
2003 – 2004: 名古屋大学, 環境医学研究所, 教授
2001: 名古屋大学, 環境医学研究所, 教授
1998: Nara Med.Univ., Dept.Neurol., Assoc.Prof., 神経内科, 助教授 … More
1996 – 1998: 奈良県立医科大学, 医学部, 助教授
1994: Fujita Health Univ., Dept.Neurol., Assist.Prof., 医学部, 講師
1993: 藤田保健衛生大学, 医学部・神経内科, 講師
1992: 藤田保健衛生大学, 医学部, 講師
1991: Fujita Health University, Department of Neurology, Assistant Prof., 医学部・神経内科, 講師
1989 – 1990: 藤田学園保健衛生大学, 医学部・神経内科, 講師 Less
Review Section/Research Field
Principal Investigator
Neurology / Neurology / Biological Sciences
Except Principal Investigator
Neurology
Keywords
Principal Investigator
サイトカイン / ミクログリア / multiple sclerosis / cytokine / microglia / IL-18 / IL-13 / AIDS / 多発性硬化症 / IL-4 … More / IL-10 / Retrovirus / Microglia / Astrocyte / レトロウイルス / アストロサイト / 脱髄 / ウイルス / neuronal degeneration / 神経変性 / glia / 中枢神経系 / IL-12 / グリア / Cytokine / CD4 / HIV / サイトカインネットワーク / MHC antigens / Cytokines / Demylination / Oligodendrocyte / Glia / 抗原呈示 / オリゴデンドロサイド / 主要組織適合性抗原 / マクロファ-ジ / tax遺伝子 / オリゴデンドロサイト / グリア細胞 / タイラーウイルス / 遺伝子 / 細胞・組織 / 脳神経疾患 / 脳・神経 … More
Except Principal Investigator
ALS / アストロサイト / 神経変性疾患 / 神経免疫 / 脳神経疾患 / 調節性T細胞 / 炎症性脱髄 / ミッドカイン Less
  • Research Projects

    (7 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (17 People)
  •  Elucidating pathomechanism of ALS through the abnormality in astrocytes

    • Principal Investigator
      YAMANAKA Koji
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  The role of midkine family in inflammatory demyelination

    • Principal Investigator
      MIZUNO Tetsuya
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  The role of microglia on the development of neurological disordersPrincipal Investigator

    • Principal Investigator
      SUZUMURA Akio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  タイラーウイルスによる免疫性脱髄の発症機序に関する研究Principal Investigator

    • Principal Investigator
      錫村 明生
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Roles of microglia on the development of neurological disordersPrincipal Investigator

    • Principal Investigator
      SUZUMURA Akio
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nara Med.University, Depatment of Neurology
  •  The role of microglia in the pathogenesis of the central nervous systemPrincipal Investigator

    • Principal Investigator
      SUZUMURA Akio
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Fujita Health University
  •  The mechanisms of demyelinating neurological diseasesPrincipal Investigator

    • Principal Investigator
      SUZUMURA Akio
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Fujita Health University

All 2008 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 神経免疫学(黒川清, 松澤佑次(編))、内科学教科書(第2版)2003

    • Author(s)
      錫村明生
    • Publisher
      文光堂、東京
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity2008

    • Author(s)
      Liang J, Mizuno T, Suzumura A 他(11人10番目)
    • Journal Title

      Brain Research 1210

      Pages: 11-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Microglia express a functional receptor for interleukin-23.2008

    • Author(s)
      SONOBE Yoshifumi, MIZUNO Tetsuya, SUZUMURA Akio
    • Journal Title

      Biochemical and Biophysical Research Communic ations. 370

      Pages: 129-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Interferon-γ directly induces neurotoxicity through a neuron specific, calciumpermeable complex of IFN-γ receptor and AMPA GluR1 receptor.2008

    • Author(s)
      MIZUNO Tetsuya, SUZUMURA Akio
    • Journal Title

      FASEB Journal 22

      Pages: 1797-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Production and functions of IL-17 in microglia2008

    • Author(s)
      Kawanokuchi J, Mizuno T, Suzumura A 他(7人5番目)
    • Journal Title

      Journal of Neuroimmunology 194

      Pages: 54-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Microglia express a functional receptor for interleukin-232008

    • Author(s)
      Sonobe Y, Mizuno T, Suzumura A 他(7人6番目)
    • Journal Title

      Biochemical and Biophysical Research Communications 370

      Pages: 129-133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity.2008

    • Author(s)
      LIANG Jianfeng, MIZUNO Tetsuya, SUZUMURA Akio
    • Journal Title

      Brain Research 1210

      Pages: 11-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Interferon-. directly induces neurotoxicity through a neuron specific, calcium- permeable complex of IFN- receptor and AMPA GluR1 receptor2008

    • Author(s)
      Mizuno T, Suzumura A 他(10人1番目)
    • Journal Title

      FASEB Journal 22

      Pages: 1797-1806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Production and functions of IL-17 in microglia.2008

    • Author(s)
      Kawanokuchi J, Mizuno T, Suzumura A,
    • Journal Title

      Journal of Neuroimmunology 194

      Pages: 54-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Production of interferon-γby microglia.2006

    • Author(s)
      Kawanokuchi J, Mizuno T, Takeuchi H, Kato H, Wang J, Mitsuma N, Suzumura A
    • Journal Title

      Multiple Sclerosis 12

      Pages: 558-564

    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Role of glia-derived cytokines on neuronal degeneration and regeneration2006

    • Author(s)
      Suzumura A, Takeuchi H, Zhang G, Kuno R, Mizuno T
    • Journal Title

      Annals of New York Academy of Science 1088

      Pages: 219-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Production of interferon-2006

    • Author(s)
      Kawanokuchi J, Mizuno T, Takeuchi H, Kato H, Wang J, Mitsuma N, Suzumura A
    • Journal Title

      by microglia Multiple Sclerosis 12

      Pages: 558-564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Midkine deficiency protects against Experimental Autoimmnue Encephalomyelitis by expansion of CD4^+CD25^+Foxp3^+ regulatory T cells.2006

    • Author(s)
      Wwng J, Takeuchi H, Jin S, Sonobe Y, Mizuno T, Muramatsu H, Muramatsu T, Suzumura A
    • Journal Title

      Journal of Neuroimmunology 178

      Pages: 169-169

    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Role of glia-derived cytokines on neuronal degeneration and regeneration.2006

    • Author(s)
      Suzumura A, Takeuchi H, Zhang G, Kuno R, Mizuno T
    • Journal Title

      Annals of New York Academy of Science 1088

      Pages: 219-229

    • Data Source
      KAKENHI-PROJECT-18590933
  • [Journal Article] Effects of interferon-beta on the cytokine production of astrocytes.2005

    • Author(s)
      Okada K, Kuroda E, Yoshida Y, Yamashita U, Suzumura A, Tsuji S.
    • Journal Title

      J Neuroimmunol 159(1-2)

      Pages: 48-54

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] The radical scavenger edaravone prevents oxidative neurotoxicity by peroxynitrite and by activated microglia.2005

    • Author(s)
      Banno, M., Mizuno, T., Kato, H., Zang, G., Kawanokuchi, J., Kuno, R., Jin, S., Takeuchi, H., Suzumura, A.
    • Journal Title

      Neuropharmacol. 48

      Pages: 283-290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Autocrine activation of microglia by tumor necrosis factor-α.2005

    • Author(s)
      Kuno, R., Wang, J., Kawanokuchi, J., Takeuchi, H., Mizuno, T., Suzumura, A.
    • Journal Title

      J.Neuroimmunol 162

      Pages: 89-96

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] The radical scavenger edaravone prevents oxidative neurotoxicity by peroxynitrite and by activated microglia.2005

    • Author(s)
      Banno, M., Mizuno, T., Kato, H., Zang, G., Suzumura.A.
    • Journal Title

      Neuropharmacol. 48

      Pages: 283-290

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Autocrine activation of microglia by tumor necrosis factor-α.2005

    • Author(s)
      Kuno, R., Wang, J., Kawanokuchi, J., Takeuchi, H., Mizuno, T., Suzumura, A.
    • Journal Title

      J Neuroimmunol. 162

      Pages: 89-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations.2005

    • Author(s)
      Sonobe, Y., Yawata, I., Kawanokuchi, J., Takeuchi, H., Mizuno, T., Suzumura, A.
    • Journal Title

      Brain Res. 1040

      Pages: 202-207

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport.2005

    • Author(s)
      Takeuchi, H., Mizuno T, Zhang G, Wang J, Kawanokuchi J, Kuno R, Suzumura A.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 10444-10454

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Effects of interferon-beta on the cytokine production of astrocytes.2005

    • Author(s)
      Okada K, Kuroda E, Yoshida Y, Yamashita U, Suzumura A, Tsuji S.
    • Journal Title

      J Neuroimmunol. 159(1-2)

      Pages: 48-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) ameliorates experimental autoimmune encephalomyelitis2004

    • Author(s)
      Kato, H., Ito, A., Jin, S., Mizuno, T., Suzumura, A.
    • Journal Title

      Multiple Scler. 10

      Pages: 651-659

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Ibudilast, a nonselective phosphodiesterase inhibitor, regulates Th1/Th2 balance and NKT cell subset in multiple sclerosis.2004

    • Author(s)
      Feng.J., Misu, T., Fujihara, K., Sakoda, S., Nakatsuji, Y., Fukaura, H., Kikuchi, S., Tashiro, K., Suzumura, A., Ishii, N., Sugamura, K., Nakashima, I., Itoyama, Y.
    • Journal Title

      Multiple Scler. 10

      Pages: 494-498

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Ibudilast, a nonselective phosphodiesterase inhibitor, regulates Th1/Th2 balance and NKT cell subset in multiple sclerosis.2004

    • Author(s)
      Feng, J., Misu, T., Fujihara, K., Sakoda, S., Nakatsuji, Y., Suzumura, A.
    • Journal Title

      Multiple Scler. 10

      Pages: 494-498

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Pituitary Adenylate Cyclase-Activating Polypeptide(PACAP) ameliorates experimental autoimmune encephalomyelitis2004

    • Author(s)
      Kato, H., Ito, A., Jin, S., Mizuno, T., Suzumura, A.
    • Journal Title

      Multiple Scler. 10

      Pages: 651-659

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia.2004

    • Author(s)
      Mizuno, T., Kurotani, T., Komatsu, Y., Kawanokuchi, J., Kato, H., Mitsuma, N., Suzumura, A.
    • Journal Title

      Neuropharmacol. 46

      Pages: 404-411

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Effects of interferon-β on microglial functions as inflammatory and antigen presenting cells in the central nervous system.2004

    • Author(s)
      Kawanokuchi, J., Mizuno, T., Kato, H., Mitsuma, N., Suzumura, A.
    • Journal Title

      Neuropharmacol. 46

      Pages: 734-742

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Effects of interferon-on microglial functions as inflammatory and antigen presenting cells in the central nervous system.2004

    • Author(s)
      Kawanokuchi, J., Mizuno, T., Kato, H., Mitsuma, N., Suzumura, A.
    • Journal Title

      Neuropharmacol. 46

      Pages: 734-742

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Occurrence of the spinal reflex due to skin pressure in sudomotor and cutaneous vasoconstrictor nerv system of humans.2003

    • Author(s)
      Okagawa, T., Sugenoya, J., Iwase, S., Mano, T., Suzumura, A., Matsumoto, T., Sugiyama, Y.
    • Journal Title

      Auton.Neurosci. 105

      Pages: 62-70

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] 脳病巣のサイトカイン動態2003

    • Author(s)
      加藤秀紀, 錫村明生
    • Journal Title

      日本臨床 61

      Pages: 1428-1434

    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Phosphodiesterase inhibitors suppress IL-12 production with microglia and T helper 1 development.2003

    • Author(s)
      Suzumura, A., Ito.A, Mizuno, T.
    • Journal Title

      Multiple Scler. 9

      Pages: 574-578

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Production and neuroprotective functions of fractalkine in the central nervous system.2003

    • Author(s)
      Mizuno, T., Kawanokuchi, J., Numata, K., Suzumura, A.
    • Journal Title

      Brain Res. 979

      Pages: 65-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Occurrence of the spinal reflex due to skin pressure in sudomotor and cutaneous vasoconstrictor nerve system of humans.2003

    • Author(s)
      Okagawa, T., Sugenoya, J., Iwase, S., Mano, T., Suzumura, A., Matsumoto, T., Sugiyama, Y.
    • Journal Title

      Auton.Neurosci. 105

      Pages: 62-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Phosphodiesterase inhibitors suppress IL-12 production with microglia and T helper 1 development.2003

    • Author(s)
      Suzumura, A., Ito, A., Mizuno, T.
    • Journal Title

      Multiple Scler. 9

      Pages: 574-578

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Journal Article] Production and neuroprotective functions of fractalkine in the central nervous system2003

    • Author(s)
      Mizuno, T., Kawanokuchi, J., Numata, K., Suzumura, A.
    • Journal Title

      Brain Res. 979

      Pages: 65-70

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590886
  • [Presentation] 中枢神経系におけるインターロイキン-25の発現とその機能2008

    • Author(s)
      片岡邦夫、水野哲也、錫村明生
    • Organizer
      第20回神経免疫学会学術集会
    • Place of Presentation
      新潟
    • Year and Date
      2008-04-17
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Presentation] 中枢神経系におけるインクーロイキン-25の発現とその機能2008

    • Author(s)
      片岡邦夫, 水野哲也, 錫村明生
    • Organizer
      第20回神経免疫学会学術集会
    • Place of Presentation
      新潟
    • Year and Date
      2008-04-17
    • Data Source
      KAKENHI-PROJECT-18590933
  • [Presentation] Midkine欠損マウスでは制御性T細胞の増加によりEAEの発症が抑制される2006

    • Author(s)
      竹内英之、王金岩、水野哲也、錫村明生
    • Organizer
      第47回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-11
    • Data Source
      KAKENHI-PROJECT-18590933
  • 1.  SAWADA Makoto (10187297)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YAMAMOTO Hiroko (20148258)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  MIZUNO Tetsuya (70335008)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 31 results
  • 4.  TAMARU Tsukasa (50295797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TAKAYANAGI Tetsuya (60022836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YAMANAKA Koji (80446533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Takeuchi Hideyuki (30362213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Takahashi Ryosuke (90216771)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Yamashita Hirofumi (60402913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  朝倉 邦彦 (50333159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  村田 顕也 (90264853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  小峯 起 (00456211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  高橋 英機 (40446521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  三澤 日出巳 (80219617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  内匠 透 (00222092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Endo Fumito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Watanabe Seiji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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