Hirata Makoto 平田真

… Alternative Names

HIRATA Makoto 平田真

Less

Researcher Number	50401071
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 中央病院, 部門長
Affiliation (based on the past Project Information) *help	2023 – 2025: 国立研究開発法人国立がん研究センター, 中央病院, 部門長 2021 – 2022: 国立研究開発法人国立がん研究センター, 中央病院, 医長 2018 – 2020: 国立研究開発法人国立がん研究センター, 中央病院, 医員 2015 – 2017: 東京大学, 医科学研究所, 特任助教 2014: 東京大学, 医科学研究所, 助教 … More 2011 – 2014: 東京大学, 医学部附属病院, 届出診療医 2013: 東京大学, 医学(系)研究科(研究院), 届出診療医 2013: 東京大学, 医学部附属病院, その他 2011: 東京大学, 医学(系)研究科(研究院), 特任助教 2010: 東京大学, 医学系研究科, 特任助教 Less
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Tumor therapeutics / Tumor biology / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 骨軟部腫瘍 / 全ゲノム解析 / 機能解析 / ゲノム解析 / 代謝 / 軟骨 / 腫瘍 / イソクエン酸デヒドロゲナーゼ / 軟骨腫瘍 / ADAMTS / MMP / 軟骨肉腫 / C/EBPβ … More Except Principal Investigator … More ゲノム / 肉腫 / 骨軟部腫瘍 / プロテオームデータベース / プロテオーム / プロテオゲノミクス / 癌 / 変形性関節症 / 遺伝子解析 / 悪性軟部腫瘍 / バイオマーカー / プロテオミクス / 骨軟部肉腫 / 整形外科 / 融合遺伝子 / がんゲノム / ゲノム解析 / 軟骨肉腫 / 血管形成 / 軟骨 / デスモイド / 骨・軟部腫瘍学 / 性ホルモン / RANKL / RANKLシグナル / 骨肉腫 / アディポネクチン / レジスチン / アディポカイン Less

骨軟部腫瘍易罹患性に係る遺伝性腫瘍の全ゲノム解析に基づく包括的管理体系構築の検討Principal Investigator
- Principal Investigator
  
  平田真
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cancer Center Japan
Exploration of Cancer predisposition using cutting edge technologies for genome analysis.
- Principal Investigator
  
  加藤元博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  The University of Tokyo
Elucidation of molecular backgrounds of disease and development of therapeutic approach in bone and soft tissue sarcomas using proteogenomics and biobank resource
- Principal Investigator
  
  川井章
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cancer Center Japan
骨軟部腫瘍全ゲノム解析データに基づく遺伝子異常の機能解析と治療標的の同定Principal Investigator
- Principal Investigator
  
  平田真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cancer Center Japan
Discovery of innovative seeds for diagnosis and treatment in bone and soft-tissue sarcomas by proteogenomic approach
- Principal Investigator
  
  Kawai Akira
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cancer Center Japan
Development of personalized soft tissue sarcoma therapies through the integrated genomic analysis
- Principal Investigator
  
  中谷文彦
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cancer Center Japan
Functional analysis of genomic mutations and screening of novel drug, based on comprehensive genomic analysis of muscloskeletal tumorsPrincipal Investigator
- Principal Investigator
  
  Hirata Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  National Cancer Center Japan
  The University of Tokyo
Identification of diagnostic biomarker and novel fusion genes of bone and soft tissue sarcoma
- Principal Investigator
  
  Matsuda Koichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Analysis of cartilage-specific IDH mutant mice for explication of underlying mechanism in chondrosarcoma developmentPrincipal Investigator
- Principal Investigator
  
  Hirata Makoto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
To elucidate the mechanism of tranilast treatment on extra-abdominal desmoid tumor
- Principal Investigator
  
  SHINODA Yusuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Regulatory mechanism of vascularization in cartilage tissue
- Principal Investigator
  
  ISHII Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Novel therapeutic strategy of osteosarcoma by regulation of RANK signal pathway
- Principal Investigator
  
  KAWANO Hirotaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
軟骨肉腫治療を目指した転写因子C/EBPβによる基質分解関連因子制御機構の解明Principal Investigator
- Principal Investigator
  
  平田真
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
脂質代謝調節因子アディポカインによる軟骨代謝調節機構の検討
- Principal Investigator
  
  廣田仁聡
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo

[Book] 骨軟部腫瘍の診断と治療／骨軟部腫瘍ゲノムコンソーシアム2017
- Author(s)
  平田真ほか
- Total Pages
  552
- Publisher
  アークメディア
- ISBN
  9784875832164
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Evaluation of the pathogenic potential of germline DDX41 variants in hematopoietic neoplasms using the ACMG/AMP guidelines2024
- Author(s)
  Matsui Hirotaka、Hirata Makoto
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 5 Pages: 552-563
- DOI
  10.1007/s12185-024-03728-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08419, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24468
[Journal Article] Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes2024
- Author(s)
  Nakamura Wataru、Hirata Makoto、 Akira、Kawai、Noguchi Michio、Umezawa Akihiro、Ito Shuichi、Yoshida Teruhiko、Shiraishi Yuichi、NCBN Controls WGS Consortium　et al
- Journal Title
  
  npj Genomic Medicine
  
  Volume: 9 Issue: 1 Pages: 11-11
- DOI
  10.1038/s41525-024-00394-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-21H03549, KAKENHI-PROJECT-23K24468
[Journal Article] A Learning Program for Treatment Recommendations by Molecular Tumor Boards and Artificial Intelligence.2024
- Author(s)
  Sunami K, Naito Y, Saigusa Y, Amano T, Ennishi D, Imai M, Kage H, Kanai M, Kenmotsu H, Komine K, Koyama T, Maeda T, Morita S, Sakai D, Hirata M, et al
- Journal Title
  
  JAMA Oncol.
  
  Volume: 10 Issue: 11 Pages: 95-102
- DOI
  10.1136/bmjopen-2023-072472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24468
[Journal Article] Identification of barriers to implementation of precision oncology in patients with rare cancers.2024
- Author(s)
  Takamizawa S, Koyama T, Sunami K, Sudo K, Hirata M, Kubo T, Tao K, Cho H, Narita Y, Kato K, Yamazaki N, Ohe Y, Okusaka T, Matsui Y, Ogawa C, Yonemori K, Yamamoto N.
- Journal Title
  
  Cancer Sci.
  
  Volume: Online ahead of print. Issue: 6 Pages: 2023-2035
- DOI
  10.1111/cas.16165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24468
[Journal Article] Pathogenic Germline Variants in BRCA1/2 and p53 Identified by Real-world Comprehensive Cancer Genome Profiling Tests in Asian Patients.2023
- Author(s)
  Satake T, Kondo S, Tanabe N, Mizuno T, Katsuya Y, Sato J, Koyama T, Yoshida T, Hirata M, Yamamoto N.
- Journal Title
  
  Cancer Res Commun.
  
  Volume: 3 Issue: 11 Pages: 2302-2311
- DOI
  10.1158/2767-9764.crc-23-0018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24468
[Journal Article] Pediatric Precision Medicine at the National Cancer Center Japan: Prospective Genomic Study of Pediatric Patients with Cancer as Part of the TOP-GEAR Project2023
- Author(s)
  Tao Kayoko、Ohira Miki、他19名
- Journal Title
  
  JCO Precision Oncology
  
  Volume: 7 Issue: 7
- DOI
  10.1200/po.22.00266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08269, KAKENHI-PROJECT-23K07239, KAKENHI-PROJECT-19H03625, KAKENHI-PROJECT-23K24468, KAKENHI-PROJECT-23K27389
[Journal Article] KDM2B-Rearranged Soft Tissue Sarcomas Expand the Concept of BCOR-Associated Sarcoma2023
- Author(s)
  Motoi Toru、Hirata Makoto、Kukita Yoji、Satomi Kaishi、Tamura Hiromi、Adachi Shiro、Matsushita Yuko、Horiguchi Shin-ichiro、Hishima Tsunekazu、Ikegami Masachika、Okuma Tomotake、Tao Kayoko、Arakawa Ayumu、Ogawa Chitose、Matsuda Koichi、Ichimura Koichi、Nakamura Harumi、Mori Taisuke、Yoshida Akihiko
- Journal Title
  
  Modern Pathology
  
  Volume: 36 Issue: 11 Pages: 100317-100317
- DOI
  10.1016/j.modpat.2023.100317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06919, KAKENHI-PROJECT-22K06951, KAKENHI-PROJECT-22K06952, KAKENHI-PROJECT-22K15571, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] A complex rearrangement between APC and TP63 associated with familial adenomatous polyposis identified by multimodal genomic analysis: a case report2023
- Author(s)
  Oda Satoyo、Ushiama Mineko、Nakamura Wataru、Gotoh Masahiro、Tanabe Noriko、Watanabe Tomoko、Odaka Yoko、Aoyagi Kazuhiko、Sakamoto Hiromi、Nakajima Takeshi、Sugano Kokichi、Yoshida Teruhiko、Shiraishi Yuichi、Hirata Makoto
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 13 Pages: 1205847-1205847
- DOI
  10.3389/fonc.2023.1205847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants.2022
- Author(s)
  Momozawa Yukihide、Sasai Rumi、Usui Yoshiaki、Taniyama Yukari、Parsons Michael T、Mizukami Keijiro、Sekine Yuya、Hirata Makoto、Kubo Michiaki、et al.
- Journal Title
  
  JAMA Oncology
  
  Volume: 未定 Issue: 6 Pages: 871-871
- DOI
  10.1001/jamaoncol.2022.0476
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-20H03695, KAKENHI-PROJECT-21K19492, KAKENHI-PROJECT-23K24468
[Journal Article] Imaging characteristics of NTRK-rearranged spindle cell neoplasm of the soft tissue: A case report.2022
- Author(s)
  Takamiya Akihiro、Ishibashi Yuki、Makise Naohiro、Hirata Makoto、Ushiku Tetsuo、Tanaka Sakae、Kobayashi Hiroshi.
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: S0949-2658(21) Issue: 6 Pages: 00367-5
- DOI
  10.1016/j.jos.2021.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-20K09453, KAKENHI-PROJECT-20K16167, KAKENHI-PROJECT-23K06438
[Journal Article] Pleomorphic rhabdomyosarcoma in a young adult harboring a novel germline MSH2 variant.2022
- Author(s)
  Tomida Akimasa、Chiyonobu Tomohiro、Tokuda Shinsaku、Miyachi Mitsuru、Murashima Kyoko、Hirata Makoto、Nakagawa Masanori、Iehara Tomoko、Kuroda Junya、Takayama Koichi.
- Journal Title
  
  Human Genome Variation
  
  Volume: 9(1) Issue: 1 Pages: 8-8
- DOI
  10.1038/s41439-022-00185-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03062
[Journal Article] Expert panel consensus recommendations on the use of circulating tumor DNA assays for patients with advanced solid tumors2022
- Author(s)
  Imai M, Nakamura Y, Sunami K, Kage H, Komine K, Koyama T, Amano T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S, Sakai D, Bando H, Makiyama A, Suzuki T, Hirata M, Kohsaka S, Tsuchihara K, Naito Y, Yoshino T
- Journal Title
  
  Cancer Sci
  
  Volume: 113 Issue: 11 Pages: 3646-3656
- DOI
  10.1111/cas.15504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] Case report: Response to platinum agents and poly (adenosine diphosphate-ribose) polymerase inhibitor in a patient with BRCA1 c.5096G>A (R1699Q) intermediate-risk variant2022
- Author(s)
  Saito Ayumi、Tanioka Maki、Hirata Makoto、Watanabe Tomoko、Odaka Yoko、Shimoi Tatsunori、Sudo Kazuki、Noguchi Emi、Ishikawa Mitsuya、Yonemori Kan
- Journal Title
  
  Cancer Treatment and Research Communications
  
  Volume: 32 Pages: 100587-100587
- DOI
  10.1016/j.ctarc.2022.100587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09636, KAKENHI-PROJECT-23K24468
[Journal Article] Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.2022
- Author(s)
  Naito Y, Sunami K, Kage H, Komine K, Amano T, Imai M, Koyama T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S, Sakai D, Watanabe K, Shirota H, Kinoshita I, Yoshioka M, Mamesaya N, Ito M, Kohsaka S, Saigusa Y, Yamamoto K, Hirata M, Tsuchihara K, Yoshino T.
- Journal Title
  
  JAMA Netw Open.
  
  Volume: 5 Issue: 12 Pages: 2245081-2245081
- DOI
  10.1001/jamanetworkopen.2022.45081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07183, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-23K24468
[Journal Article] Comprehensive molecular and clinicopathological profiling of desmoid tumours2021
- Author(s)
  Kohsaka Shinji、Hirata Makoto、Ikegami Masachika、Ueno Toshihide、Kojima Shinya、Sakai Tomohisa、Ito Kan、Naka Norifumi、Ogura Koichi、Kawai Akira、Iwata Shintaro、Okuma Tomotake、Yonemoto Tsukasa、Kobayashi Hiroshi、Suehara Yoshiyuki、Hiraga Hiroaki、Kawamoto Teruya、Motoi Toru、Oda Yoshinao、Matsubara Daisuke、etc
- Journal Title
  
  European Journal of Cancer
  
  Volume: 145 Pages: 109-120
- DOI
  10.1016/j.ejca.2020.12.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-20K16328, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Myxofibrosarcoma harboring an MLH1 pathogenic germline variant associated with Muir-Torre syndrome: a case report.2021
- Author(s)
  Nakagawa Makoto、Kobayashi Eisuke、Yamada Masayoshi、Watanabe Tomoko、Hirata Makoto、Tanabe Noriko、Ushiama Mineko、Sakamoto Hiromi、Sato Chiaki、Mori Taisuke、Yoshida Akihiko、Yoshida Teruhiko、Sugano Kokichi、Kawai Akira.
- Journal Title
  
  Hereditary Cancer in Clinical Practice
  
  Volume: 19 Issue: 1 Pages: 34-34
- DOI
  10.1186/s13053-021-00192-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03062
[Journal Article] Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis.2021
- Author(s)
  Liu Xun、Yamaguchi Kiyoshi、Takane Kiyoko、Zhu Chi、Hirata Makoto、Hikiba Yoko、Maeda Shin、Furukawa Yoichi、Ikenoue Tsuneo.
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 9 Pages: 0257090-0257090
- DOI
  10.1371/journal.pone.0257090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03062, KAKENHI-PROJECT-21K07975, KAKENHI-PROJECT-20K17641, KAKENHI-PROJECT-20K07563
[Journal Article] Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction2020
- Author(s)
  Sakaue S, Hirata J, Kanai M, Suzuki K, Akiyama M, Lai Too C, Arayssi T, Hammoudeh M, Al Emadi S, Masri BK, Halabi H, Badsha H, Uthman IW, Saxena R, Padyukov L, Hirata M, Matsuda K, Murakami Y, Kamatani Y, Okada Y
- Journal Title
  
  Nat Commun
  
  Volume: 11 Issue: 1 Pages: 1569-1569
- DOI
  10.1038/s41467-020-15194-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-19H01021, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-19K17962
[Journal Article] Fine Mapping of the Major Histocompatibility Complex Region and Association of the HLA-B*52:01 Allele With Cervical Cancer in Japanese Women2020
- Author(s)
  Masuda Tatsuo、Ito Hidemi、Hirata Jun、Sakaue Saori、Ueda Yutaka、Kimura Tadashi、Takeuchi Fumihiko、Murakami Yoshinori、Matsuda Koichi、Matsuo Keitaro、Okada Yukinori
- Journal Title
  
  JAMA Network Open
  
  Volume: 3 Issue: 10 Pages: e2023248-e2023248
- DOI
  10.1001/jamanetworkopen.2020.23248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-19H01021
[Journal Article] Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan2020
- Author(s)
  Sakaue S, Kanai M, Karjalainen J, Akiyama M, Kurki M, Matoba N, Takahashi A, Hirata M, Kubo M, Matsuda K, Murakami Y; FinnGen, Daly MJ, Kamatani Y, Okada Y
- Journal Title
  
  Nat Med
  
  Volume: 26 Issue: 4 Pages: 542-548
- DOI
  10.1038/s41591-020-0785-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-19H01021, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-16H02676
[Journal Article] Identification of a novel uterine leiomyoma GWAS locus in a Japanese population2020
- Author(s)
  Sakai Kensuke、Tanikawa Chizu、Hirasawa Akira、Terao Chikashi、Kamatani Yoichiro、Takahashi Atsushi、Momozawa Yukihide、Hirata Makoto、Kubo Michiaki、Matsuda Koichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1024-1024
- DOI
  10.1038/s41598-020-58066-8
- NAID
  120006872359
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22525, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-19H03881, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K11420, KAKENHI-PROJECT-20K09630, KAKENHI-PROJECT-17K19611
[Journal Article] Population-based Screening for Hereditary Colorectal Cancer Variants in Japan2020
- Author(s)
  Fujita Masashi、Liu Xiaoxi、Iwasaki Yusuke、Terao Chikashi、Mizukami Keijiro、Kawakami Eiryo、Takata Sadaaki、Inai Chihiro、Aoi Tomomi、Mizukoshi Misaki、Maejima Kazuhiro、Hirata Makoto、Murakami Yoshinori、Kamatani Yoichiro、Kubo Michiaki、Akagi Kiwamu、Matsuda Koichi、Nakagawa Hidewaki、Momozawa Yukihide
- Journal Title
  
  Clinical Gastroenterology and Hepatology
  
  Volume: 20 Issue: 9 Pages: 31664-31665
- DOI
  10.1016/j.cgh.2020.12.007
- Data Source
  KAKENHI-PROJECT-16H02676
[Journal Article] GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits.2020
- Author(s)
  Matoba N, Akiyama M, Ishigaki K, Kanai M, Takahashi A, Momozawa Y, Ikegawa S, Ikeda M, Iwata N, Hirata M, Matsuda K, Murakami Y, Kubo M, Kamatani Y, Okada Y
- Journal Title
  
  Nat Hum Behav
  
  Volume: 4 Issue: 3 Pages: 308-346
- DOI
  10.1038/s41562-019-0805-1
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-19H01021, KAKENHI-PROJECT-17H03596
[Journal Article] Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes2020
- Author(s)
  Mizukami Keijiro、Iwasaki Yusuke、Kawakami Eiryo、Hirata Makoto、Kamatani Yoichiro、Matsuda Koichi、Endo Mikiko、Sugano Kokichi、Yoshida Teruhiko、Murakami Yoshinori、Nakagawa Hidewaki、Spurdle Amanda B.、Momozawa Yukihide
- Journal Title
  
  EBioMedicine
  
  Volume: 60 Pages: 103033-103033
- DOI
  10.1016/j.ebiom.2020.103033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-18H04049
[Journal Article] GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation2019
- Author(s)
  Terao Chikashi、Momozawa Yukihide、Ishigaki Kazuyoshi、Kawakami Eiryo、Akiyama Masato、Loh Po-Ru、Genovese Giulio、Sugishita Hiroki、Ohta Tazro、Hirata Makoto、Perry John R. B.、Matsuda Koichi、Murakami Yoshinori、Kubo Michiaki、Kamatani Yoichiro
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4719-4719
- DOI
  10.1038/s41467-019-12705-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions2019
- Author(s)
  de Vries PS、Makoto Hirata、Morrison AC、et al.
- Journal Title
  
  American Journal of Epidemiology
  
  Volume: 188 Issue: 6 Pages: 1033-1054
- DOI
  10.1093/aje/kwz005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Germline Pathogenic Variants in 7636 Japanese Patients With Prostate Cancer and 12?366 Controls2019
- Author(s)
  Momozawa Yukihide、Iwasaki Yusuke、Hirata Makoto、Liu Xiaoxi、Kamatani Yoichiro、Takahashi Atsushi、Sugano Kokichi、Yoshida Teruhiko、Murakami Yoshinori、Matsuda Koichi、Nakagawa Hidewaki、Spurdle Amanda B、Kubo Michiaki
- Journal Title
  
  JNCI: Journal of the National Cancer Institute
  
  Volume: 112 Issue: 4 Pages: 369-376
- DOI
  10.1093/jnci/djz124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.2019
- Author(s)
  Suzuki K, Akiyama M, Ishigaki K, Kanai M, Hosoe J, Shojima N, Hozawa A, Kadota A, Kuriki K, Naito M, Tanno K, Ishigaki Y, et al.
- Journal Title
  
  Nat Genet.
  
  Volume: 51 Issue: 3 Pages: 379-386
- DOI
  10.1038/s41588-018-0332-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08523, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-26000012
[Journal Article] Multi-ancestry genome-wide gene?smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids2019
- Author(s)
  Bentley AR, et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 51 Issue: 4 Pages: 636-648
- DOI
  10.1038/s41588-019-0378-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09514, KAKENHI-PROJECT-17H03596
[Journal Article] Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population.2019
- Author(s)
  Hirata J, Hosomichi K, Sakaue S, Kanai M, Nakaoka H, Ishigaki K, Suzuki K, Akiyama M, Kishikawa T, Ogawa K, Masuda T, Yamamoto K, Hirata M, Matsuda K, Momozawa Y, Inoue I, Kubo M, Kamatani Y, Okada Y.
- Journal Title
  
  Nat Genet
  
  Volume: 51 Issue: 3 Pages: 470-480
- DOI
  10.1038/s41588-018-0336-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05911, KAKENHI-PLANNED-16H06502, KAKENHI-PLANNED-18H05506, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17H03596
[Journal Article] Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis2019
- Author(s)
  Okazaki S, Koizumi A 他26名(27番目)
- Journal Title
  
  Circulation
  
  Volume: 139 Issue: 2 Pages: 295-298
- DOI
  10.1161/circulationaha.118.038439
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H03596
[Journal Article] Integrated exome and RNA sequencing of dedifferentiated liposarcoma2019
- Author(s)
  Hirata Makoto、Matsubara Daisuke (21th) etc
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-019-13286-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K07791, KAKENHI-PROJECT-19K09206, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-16K08672
[Journal Article] Frequent mutations of genes encoding vacuolar H+ -ATPase components in granular cell tumors.2019
- Author(s)
  Sekimizu M, Yoshida A, Mitani S, Asano N, Hirata M, Kubo T, Yamazaki F, Sakamoto H, Kato M, Makise N, Mori T, Yamazaki N, Sekine S, Oda I, Watanabe SI, Hiraga H, Yonemoto T, Kawamoto T, Naka N, Funauchi Y, Nishida Y, Honoki K, Kawano H, Tsuchiya H, Kunisada T, Matsuda K, Inagaki K, Kawai A, Ichikawa H.
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 58 Issue: 6 Pages: 373-380
- DOI
  10.1002/gcc.22727
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10455, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-17H03596
[Journal Article] Associations of autozygosity with a broad range of human phenotypes2019
- Author(s)
  ClarkDW、Hirata M、Wilson JF、 et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4957-4957
- DOI
  10.1038/s41467-019-12283-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls.2019
- Author(s)
  Momozawa Y, Iwasaki Y, Parsons MT, Kamatani Y, Takahashi A, Tamura C, Katagiri T, Yoshida T, Nakamura S, Sugano K, Miki Y, Hirata M, Matsuda K, Spurdle AB, Kubo M.
- Journal Title
  
  Nat Commun.
  
  Volume: 9 Issue: 1 Pages: 4083-4083
- DOI
  10.1038/s41467-018-06581-8
- NAID
  120006949472
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19473, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-16H04693, KAKENHI-PROJECT-16H05153, KAKENHI-PROJECT-17K19601, KAKENHI-PROJECT-17H03596
[Journal Article] GWAS of five gynecologic diseases and cross-trait analysis in Japanese2019
- Author(s)
  Masuda Tatsuo、Low Siew-Kee、Akiyama Masato、Hirata Makoto、Ueda Yutaka、Matsuda Koichi、Kimura Tadashi、Murakami Yoshinori、Kubo Michiaki、Kamatani Yoichiro、Okada Yukinori
- Journal Title
  
  European Journal of Human Genetics
  
  Volume: 28 Issue: 1 Pages: 95-107
- DOI
  10.1038/s41431-019-0495-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18K15332
[Journal Article] Characterizing rare and low-frequency height-associated variants in the Japanese population2019
- Author(s)
  Akiyama Masato、Hirata Makoto、Kamatani Yoichiro、 et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4393-4393
- DOI
  10.1038/s41467-019-12276-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations2019
- Author(s)
  Tsuda Yusuke、Matsubara Daisuke (5th) etc
- Journal Title
  
  International Journal of Cancer
  
  Volume: 145 Issue: 12 Pages: 3276-3284
- DOI
  10.1002/ijc.32421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-18K15303
[Journal Article] GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture2019
- Author(s)
  Matoba Nana、Akiyama Masato、Ishigaki Kazuyoshi、Kanai Masahiro、Takahashi Atsushi、Momozawa Yukihide、Ikegawa Shiro、Ikeda Masashi、Iwata Nakao、Hirata Makoto、Matsuda Koichi、Kubo Michiaki、Okada Yukinori、Kamatani Yoichiro
- Journal Title
  
  Nature Human Behaviour
  
  Volume: 3 Issue: 5 Pages: 471-477
- DOI
  10.1038/s41562-019-0557-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population2019
- Author(s)
  Sakaue Saori、Akiyama Masato、Hirata Makoto、Matsuda Koichi、Murakami Yoshinori、Kubo Michiaki、Kamatani Yoichiro、Okada Yukinori
- Journal Title
  
  European Journal of Human Genetics
  
  Volume: 28 Issue: 3 Pages: 378-382
- DOI
  10.1038/s41431-019-0518-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma2018
- Author(s)
  Shiga Yukihiro、Kashiwagi Kenji、Nakazawa Toru、Kubo Michiaki、Japan Glaucoma Society Omics Group (JGS-OG)、NEIGHBORHOOD Consortium
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Issue: 8 Pages: 1486-1496
- DOI
  10.1093/hmg/ddy053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11478, KAKENHI-PROJECT-17K11482, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-18K09400, KAKENHI-PROJECT-17H03596
[Journal Article] Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries2018
- Author(s)
  Feitosa MF、Hirata M、Levy D、et al.
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 6 Pages: e0198166-e0198166
- DOI
  10.1371/journal.pone.0198166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Elucidating the genetic architecture of reproductive ageing in the Japanese population2018
- Author(s)
  Horikoshi Momoko、Day Felix R.、Akiyama Masato、Hirata Makoto、Kamatani Yoichiro、Matsuda Koichi、Ishigaki Kazuyoshi、Kanai Masahiro、Wright Hollis、Toro Carlos A.、Ojeda Sergio R.、Lomniczi Alejandro、Kubo Michiaki、Ong Ken K.、Perry John. R. B.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1977-1977
- DOI
  10.1038/s41467-018-04398-z
- NAID
  120006546004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03596
[Journal Article] Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.212018
- Author(s)
  Tanikawa C, Kamatani Y, Toyoshima O, Sakamoto H, Ito H, Takahashi A, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 4015-4024
- DOI
  10.1111/cas.13815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09095, KAKENHI-PROJECT-18K10037, KAKENHI-PROJECT-18K11420, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18H02894
[Journal Article] Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases2018
- Author(s)
  Kanai M, Akiyama M, Takahashi A, Matoba N, Momozawa Y, Ikeda M, Iwata N, Ikegawa S, Hirata M, Matsuda K, Kubo M, Okada Y, Kamatani Y
- Journal Title
  
  Nat Genet
  
  Volume: 50 Issue: 3 Pages: 390-400
- DOI
  10.1038/s41588-018-0047-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05911, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-17H04251
[Journal Article] Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13. 1.2018
- Author(s)
  Yodsurang V, Tang Y, Takahashi Y, Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Fuse N, Sugawara J, Shimizu A, Fukushima A, Hishida A, Furusyo N, Naito M, Wakai K, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Hirata M, Murakami Y, Kubo M, Matsuda K.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 12 Pages: e0209096-e0209096
- DOI
  10.1371/journal.pone.0209096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H03596
[Journal Article] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p532017
- Author(s)
  Miyamoto Takafumi、Lo Paulisally Hau Yi、Saichi Naomi、Ueda Koji、Hirata Makoto、Tanikawa Chizu、Matsuda Koichi
- Journal Title
  
  Science Advances
  
  Volume: 3 Issue: 5 Pages: 1603204-1603204
- DOI
  10.1126/sciadv.1603204
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-26710007, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596
[Journal Article] Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p532017
- Author(s)
  T. Miyamoto, P. H. Y. Lo, N. Saichi, K. Ueda, M. Hirata, C. Tanikawa, K. Matsuda
- Journal Title
  
  Science Advance
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02676
[Journal Article] Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway2017
- Author(s)
  Takahashi Yukie、Tanikawa Chizu、Miyamoto Takafumi、Hirata Makoto、Wang Guanxiong、Ueda Koji、Komatsu Tsunehiko、Matsuda Koichi
- Journal Title
  
  International Journal of Oncology
  
  Volume: 51 Issue: 2 Pages: 724-736
- DOI
  10.3892/ijo.2017.4060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-26710007, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596
[Journal Article] Identification of a novel p53 target, COL17A1, that inhibits breast cancer cell migration and invasion2017
- Author(s)
  Yodsurang Varalee、Tanikawa Chizu、Miyamoto Takafumi、Lo Paulisally Hau Yi、Hirata Makoto、Matsuda Koichi
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 34 Pages: 55790-55803
- DOI
  10.18632/oncotarget.18433
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-17H03596
[Journal Article] Genome-wide association study identifies 112 new loci for body mass index in the Japanese population2017
- Author(s)
  Akiyama M, Okada Y, Kanai M, Takahashi A, Momozawa Y, Ikeda M, Iwata N, Ikegawa S, Hirata M, Matsuda K, Iwasaki M, Yamaji T, Sawada N, Hachiya T, Tanno K, Shimizu A, Hozawa A, Minegishi N, Tsugane S, Yamamoto M, Kubo M and Kamatani Y
- Journal Title
  
  Nat Genet
  
  Volume: 49 Issue: 10 Pages: 1458-1462
- DOI
  10.1038/ng.3951
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09464, KAKENHI-PLANNED-15H05911, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H01557, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-15H05670
[Journal Article] 骨軟部腫瘍のゲノム解析2016
- Author(s)
  平田真、松田浩一
- Journal Title
  
  整形・災害外科
  
  Volume: 59 Pages: 1345-1352
- Data Source
  KAKENHI-PROJECT-15K18398
[Journal Article] Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.2016
- Author(s)
  Kobayashi H, Chang S, Mori D, Itoh S, Hirata M, Hosaka Y, Taniguchi Y, Okada K, Mori Y, Yano F, Chung U, Akiyama H, Kawaguchi H, Tanaka S, Saito T.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 13336-13336
- DOI
  10.1038/ncomms13336
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K18398, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
[Journal Article] Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype.2016
- Author(s)
  Sato S, Tang YJ, Wei Q, Hirata M, Weng A, Han I, Okawa A, Takeda S, Whetstone H, Nadesan P, Kirsch DG, Wunder JS, Alman BA.
- Journal Title
  
  Cell Rep.
  
  Volume: 16 Issue: 4 Pages: 917-27
- DOI
  10.1016/j.celrep.2016.06.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18398, KAKENHI-PROJECT-16K10847
[Journal Article] Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma.2015
- Author(s)
  Wei Q, Tang YJ, Voisin V, Sato S, Hirata M, Whetstone H, Han I, Ailles L, Bader GD, Wunder J, Alman BA.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Issue: 37 Pages: 40283-94
- DOI
  10.18632/oncotarget.5375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18398, KAKENHI-PROJECT-26893068
[Journal Article] SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.2014
- Author(s)
  Fujiwara S, Hoshikawa S, Ueno T, Hirata M, Saito T, Ikeda T, Kawaguchi H, Nakamura K, Tanaka S, Ogata T
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 12 Pages: e115400-e115400
- DOI
  10.1371/journal.pone.0115400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-26293330
[Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.2013
- Author(s)
  Hosaka Y, et al.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Issue: 5 Pages: 1875-1880
- DOI
  10.1073/pnas.1207458110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659710, KAKENHI-PROJECT-24592254
[Journal Article] Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.2013
- Author(s)
  Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Issue: 40 Pages: 28620-9
- DOI
  10.1074/jbc.m113.452169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659663, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670634
[Presentation] 骨軟部肉腫の組織型横断的マルチオミクス解析.2024
- Author(s)
  平井俊英, 片山琴絵, 白石友一, 川井章, 吉田朗彦, 小林寛, 大津敬, 国定俊之, 西田佳宏, 吉田新一郎, 近藤格, 柴田龍弘, 井元清哉, 松田浩一, 平田真.
- Organizer
  第7回日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 骨軟部肉腫の組織型横断的マルチオミクス解析2024
- Author(s)
  平井俊英, 片山琴絵, 白石友一, 川井章, 吉田朗彦, 小林寛, 大津敬, 国定俊之, 西田佳宏、吉田新一郎、近藤格、柴田龍弘、井元清哉、松田浩一、平田真
- Organizer
  第7回日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] わが国の全ゲノム解析プロジェクトにおける遺伝性腫瘍解析.2024
- Author(s)
  平田真.
- Organizer
  第21回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] わが国の全ゲノム解析プロジェクトにおける遺伝性腫瘍解析2023
- Author(s)
  平田　真
- Organizer
  第21回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] 骨軟部肉腫の全ゲノム、トランスクリプトーム解析 -先行解析-2023
- Author(s)
  平井利英、平田真、川井章、比留間徹、菊田一貴、吉田朗彦、小林寛、柴田龍弘、田中栄、松田浩一
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] Whole genome and transcriptome analysis of bone and soft tissue sarcomas.2023
- Author(s)
  Hirai T, Katayama K, Shiraishi Y, Kawai A, Yoshida A, Kobayashi H, Ohtsu T, Kunisada T, Nishida Y, Yoshida S, Kondo T, Shibata T, Imoto S, Matsuda K, Hirata M
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] Exploring hereditary cancer syndromes in the era of cancer genomic medicine.2023
- Author(s)
  Hirata M.
- Organizer
  Human Genetics Asia 2023.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 全ゲノム解析による骨・軟部肉腫146症例における遺伝性腫瘍の検討.2023
- Author(s)
  平田真, 平井利英, 小田智世, 清茜, 川井章, 比留間徹, 菊田一貴, 松田浩一, 柴田龍弘, 白石友一.
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会.
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 患者還元の検討・実践を通じて見えてきたがん領域の全ゲノム解析の可能性と課題2023
- Author(s)
  平田真
- Organizer
  第70回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Large-scale evaluation of germline variants among 11 thousand gastric cancer patients and 44 thousand controls.2023
- Author(s)
  Usui Y, Taniyama Y, Endo M, Koyanagi Y, Kasugai Y, Oze I, Ito H, Imoto I, Tanaka T, Tajika M, Niwa Y, Iwasaki Y, Aoi T, Hakozaki N, Takata S, Suzuki K, Terao C, Hatakeyama M, Hirata M, Sugano K, Yoshida T, Kamatani Y, Nakagawa H, Matsuda K, Murakami Y, Spurdle AB, Matsuo K, Momozawa Y.
- Organizer
  Human Genetics Asia 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 全ゲノム解析による骨軟部肉腫147症例における遺伝性腫瘍の検討.2023
- Author(s)
  平田真、平井利英、小田智世、清茜、川井章、比留間徹、菊田一貴、松田浩一、柴田龍弘、白石友一
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] Comprehensive Whole-genome Molecular Profiling in Bone and Soft Tissue Sarcoma; Multi-omics Analysis of 627 Cases across Histologic Subtypes2023
- Author(s)
  Hirai T, Katayama K, Shiraishi Y, Kawai A, Yoshida A, Yoshida S, Takenaka S, Outani H, Ichikawa H, Kondo T, Shibata T, Imoto S, Matsuda K, Hirata M et al
- Organizer
  CTOS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] ロングリードシーケンスデータを用いた創始者変異を含む詳細なハプロタイプの再構築のための新しいワークフロー.2023
- Author(s)
  中村航, 平田真, 須川正啓, ラウルマテオス, 千葉健一, 岡田愛, 坂本祥駿, 坂本裕美, 白石航也, 河野隆志, 吉田輝彦, 白石友一.
- Organizer
  第82回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 骨軟部肉腫の全ゲノム、トランスクリプトーム解析 -先行解析-.2023
- Author(s)
  平井利英、平田真、川井章、比留間徹、菊田一貴、吉田朗彦、小林寛、柴田龍弘、田中栄、松田浩一.
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 患者還元の検討・実践を通じて見えてきたがん領域の全ゲノム解析の可能性と課題2023
- Author(s)
  平田　真
- Organizer
  第70回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03062
[Presentation] Comprehensive Whole-genome Molecular Profiling in Bone and Soft Tissue Sarcoma; Multi-omics Analysis of 627 Cases across Histologic Subtypes.2023
- Author(s)
  Hirai T, Katayama K, Hirata M, et al.
- Organizer
  CTOS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Whole genome and transcriptome analysis of bone and soft tissue sarcomas.2023
- Author(s)
  sarcomas. Hirai T, Katayama K, Shiraishi Y, Kawai A, Yoshida A, Kobayashi H, Ohtsu T, Kunisada T, Nishida Y, Yoshida S, Kondo T, Shibata T, Imoto S, Matsuda K, Hirata M.
- Organizer
  第82回日本癌学会学術総会.
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 家族性大腸腺腫症患者における小腸ポリープの遺伝型－表現型相関の検討2022
- Author(s)
  福士剛蔵、山田真善、角川康夫、後藤政広、田辺記子、牛尼美年子、渡辺智子、山崎嵩之、松本美野里、平田真、中島健、菅野康吉、吉田輝彦、松田尚久、五十嵐良典、齋藤豊
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Adaptive samplingを用いたロングリードシークエンス解析パイプラインの構築2022
- Author(s)
  中村航、須川正啓、Nicolas Raul、飯田直子、千葉健一、小田智世、平田真、辻本信一、柴徳生、伊藤秀一、白石友一
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 遺伝性腫瘍の生殖細胞系列多遺伝子パネル解析におけるショートリードシークエンス解析・評価困難例の提示2022
- Author(s)
  牛尼美年子、後藤政広、坂本裕美、青柳一彦、平田真、田辺記子、渡辺智子、山田真善、小高陽子、小田智世、知久季倫、菅野康吉、吉田輝彦
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Attenuated FAP症例に認められたAPC遺伝子Exon14スキッピングの更新とイントロンVUSの関連について2022
- Author(s)
  後藤政広、杉山由衣、牛尼美年子、山田真善、坂本裕美、青柳一彦、田辺記子、渡辺智子、小田智世、菅野康吉、平田　真、白石航也、服部豊、吉田輝彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] RB1遺伝子バリアントを低頻度で検出した網膜芽細胞腫の症例2022
- Author(s)
  渡辺智子、牛尼美年子、田辺記子、後藤政広、小田智世、小高陽子、青柳一彦、坂本裕美、平田真、菅野康吉、鈴木茂伸、吉田輝彦
- Organizer
  第46回日本遺伝カウンセリング学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 遺伝性腫瘍に関する遺伝子パネル検査2022
- Author(s)
  平田真
- Organizer
  第40回日本染色体遺伝子検査学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 遺伝カウンセリングにおける効率的な家系情報収集・蓄積・活用を目指したシステムの研究開発と臨床実装2022
- Author(s)
  田辺記子，吾妻光洋，橋本美沙，吉川拓磨，今井健太，渡辺智子，平田真，吉田輝彦
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] STK11生殖細胞系列バリアントが検出されたPeutz-Jeghers症候群の表現型をもつ乳癌女性の一例2022
- Author(s)
  加藤芙美乃、山本英喜、十川麗美、二川摩周、浦川優作、藤原有基、田辺記子、平田真、吉田輝彦、菅野康吉、平沢晃
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 骨軟部腫瘍におけるゲノム医療/医学の現状2022
- Author(s)
  平田真
- Organizer
  第22回骨軟部腫瘍サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 遺伝子パネル解析・染色体解析によりAPC-TP63遺伝子再構成を認めた家族性大腸腺腫症の1例2022
- Author(s)
  小田智世、牛尼美年子、後藤政広、田辺記子、渡辺智子、小高陽子、青柳一彦、坂本裕美、中島健、菅野康吉、吉田輝彦、平田真
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 当院におけるLi-Fraumeni症候群患者のための多職種・多診療科連携～LFS Boardの開設～2022
- Author(s)
  平田真、田辺記子、渡辺智子、石川光也、岩田慎太郎、小村豪、小島勇貴、高橋雅道、高山伸、並川健二郎、福原傑、松井喜之、三宅基隆、森實千種、山田真善、吉田幸弘、吉田裕、渡辺祐子、吉田輝彦
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] がんゲノム医療と遺伝性腫瘍2022
- Author(s)
  平田真
- Organizer
  第25回遺伝性腫瘍セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 遺伝子パネル解析・染色体解析によりAPC-TP63遺伝子再構成を認めた家族性大腸腺腫症の1例2022
- Author(s)
  小田智世、牛尼美年子、後藤政広、田辺記子、渡辺智子、小高陽子、青柳一彦、坂本裕美、中島健、菅野康吉、吉田輝彦、平田真
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Comprehensive molecular profiling of extra-skeletal osteosarcoma2022
- Author(s)
  平井利英、平田真、松本嘉寛、大隈知威、岩田慎太郎、比留間徹、小倉浩一、西田佳弘、小林寛、田中栄、松田浩一、骨軟部腫瘍ゲノムコンソーシアム
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 初学者のための2次的所見/germline findignngsへの対応2022
- Author(s)
  平田真
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 治療のがんゲノム医療と予防のがんゲノム医療が接するところ2022
- Author(s)
  平田真
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] Liquid Biopsyにおいて病的とされたバリアントを詳細に評価する重要性～TSC2を例として～2022
- Author(s)
  村島京子、平田真、大村学、水田依久子、前田英子、千代延友裕、髙山浩一
- Organizer
  第28回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] 婦人科遺伝性腫瘍に対するゲノム医療のインパクト2022
- Author(s)
  平田真
- Organizer
  第19回日本婦人科がん会議
- Invited
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] がんゲノム情報管理センター（C-CAT）に登録された1042例の中枢神経腫瘍の遺伝子解析の現状2022
- Author(s)
  高橋雅道、小山隆文、角南久仁子、久保崇、平田真、須藤一起、渡辺祐子、宮北康二、大野誠、柳澤俊介、山本昇、成田善孝
- Organizer
  第81回日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-23K24468
[Presentation] NCCオンコパネルを用いたがん遺伝子プロファイリング研究（TOP-GEARプロジェクト第２期）における生殖細胞系列病的バリアント検出症例の特徴2019
- Author(s)
  田辺記子，角南久仁子，市川仁，久保崇，加藤護，藤原豊，下村昭彦，小山隆文，柿島裕樹，北見繭子，清水俊雄，菅野康吉，平田真，平岡伸介，田村研治，吉田輝彦，藤原康弘，河野隆志，山本昇
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] Establishment of Japan Sarcoma Genome Consortium2019
- Author(s)
  Hirata, Makoto
- Organizer
  Asia - Pacific Scientific Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] がん関連遺伝子プロファイリング検査における二次的所見の取り扱い2019
- Author(s)
  平田真
- Organizer
  第1回遺伝性腫瘍アドバンスドセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] Integrated Exome and RNA Sequencing of Dedifferentiated Liposarcoma2019
- Author(s)
  Makoto Hirata, Naofumi Asano, Kotoe Katayama, Hidewaki Nakagawa, Akira Kawai, Rui Yamaguchi, Hitoshi Ichikawa, Koichi Matsuda, Japan Sarcoma Genome Consortium
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 脱分化型脂肪肉腫119例の網羅的ゲノム解析2019
- Author(s)
  平田真、浅野尚文、片山琴絵、中川英刀、川井章、山口類、市川仁、松田浩一、骨軟部腫瘍ゲノムコンソーシアム
- Organizer
  第52回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] Precision Medicineに向けて求められるチーム医療2019
- Author(s)
  平田真、田辺記子、吉田輝彦
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 脱分化型脂肪肉腫119例の網羅的ゲノム解析2018
- Author(s)
  平田真、浅野尚文、片山琴絵、中川英刀、川井章、山口類、市川仁、松田浩一、骨軟部腫瘍ゲノムコンソーシアム
- Organizer
  第2回日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 臨床情報データベースに基づくバイオバンク・ジャパン試料検索システムの構築2018
- Author(s)
  松田浩一、平田真、村上善則
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] Integrated Whole Exome and RNA Sequencing for Dedifferentiated Liposarcoma2018
- Author(s)
  Hirata M, Asano N, Katayama K, Yamaguchi R, Ichikawa H, Matsuda K、et al.
- Organizer
  CTOS2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 臨床情報データベースに基づくバイオバンク・ジャパン試料検索システムの構築2018
- Author(s)
  松田浩一、平田真、武藤香織、永井亜貴子、森崎隆幸、村上善則
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] ヒト変異型IDH1/IDH2発現肉腫マウスモデルの確立2018
- Author(s)
  平田真、Jay Wunder、Benjamin Alman、松田浩一
- Organizer
  第13回関東骨軟部腫瘍の基礎を語る会春のセミナー
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 一郎. 喫煙，飲酒や食生活への遺伝的寄与に基づく多因子疾患との遺伝学的関連の解明2018
- Author(s)
  的場奈々、秋山雅人、石垣和慶、金井仁弘、高橋篤、桃沢幸秀、池川志郎、池田匡志、岩田仲生、平田真、松田浩一、久保充明、岡田随象、鎌谷洋一郎
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] NGS時代の遺伝性腫瘍診療の遺伝カウンセリングの現場から2018
- Author(s)
  吉田輝彦、青柳一彦、牛尼美年子、後藤政広、坂本裕美、田辺記子、平田真、菅野康吉
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] IDH1/2変異発現マウスを用いた新規内軟骨腫症モデルの検討2017
- Author(s)
  平田真、Benjamin A. Alman、Jay S. Wunder、松田浩一
- Organizer
  第14回関東骨軟部腫瘍の基礎を語る会春のセミナー
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 臨床情報データベースに基づくバイオバンク・ジャパン試料検索システムの構築.2017
- Author(s)
  平田真、井元清哉、湯地晃一郎、古川洋一、村上善則、松田浩一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 臨床情報データベースに基づくバイオバンク・ジャパン試料検索システムの構築2017
- Author(s)
  平田真、井元清哉、湯地晃一郎、古川洋一、村上善則、松田浩一
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] IDH Mutations and 2HG Levels Predict Survival in Chondrosarcoma.2017
- Author(s)
  Makoto Hirata, Nalan Gokgoz, Qingxia Wei, Shing Sato, Yuning J Tang, Irene L Andrulis, Benjamin A Alman, Jay S Wunder.
- Organizer
  The 19th International Society of Limb Salvage General Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03596
[Presentation] 骨軟部腫瘍のゲノム解析～脱分化型脂肪肉腫の全エクソンシークエンス解析～2016
- Author(s)
  平田真、浅野尚文、片山琴絵、津田祐輔、元井亨、五嶋孝博、岩本幸英、小田義直、岩田慎太郎、西田佳弘、平賀博明、比留間徹、小林寛、荒木信人、河野博隆、中川英刀、井元清哉、宮野悟、山口類、市川仁、松田浩一、Japan Sarcoma Genome Consortium
- Organizer
  第13回関東骨軟部腫瘍の基礎を語る会春のセミナー
- Place of Presentation
  伊豆の国, 静岡
- Year and Date
  2016-04-09
- Data Source
  KAKENHI-PROJECT-15K18398
[Presentation] Establishment of Japanese Sarcoma Genome Consortium (JSGS) for genomic analysis.2016
- Author(s)
  Makoto Hirata, Koichi Matsuda
- Organizer
  CTOS2016 Annual Meeting
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18398
[Presentation] 軟骨肉腫におけるIDH1/2変異による層別化臨床情報解析2016
- Author(s)
  平田真, 松田浩一, Benjamin Alman, Jay Wunder
- Organizer
  第14回関東骨軟部腫瘍の基礎を語る会
- Place of Presentation
  東京
- Year and Date
  2016-10-29
- Data Source
  KAKENHI-PROJECT-15K18398
[Presentation] D-2HG levels and IDH mutation type correlate with disease free survival in chondrosarcoma.2016
- Author(s)
  Makoto Hirata, Nalan Gokgoz, Qingxia Wei, Shingo Sato, Yuning J. Tang, Irene L. Andrulis, Benjamin Alman, Jay Wunder
- Organizer
  CTOS2016 Annual Meeting
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18398
[Presentation] Mesenchymal tumors can derive from Ng2-expressing pericytes with β-catenin modulating the neoplastic phenotype.2016
- Author(s)
  Shingo Sato, Yuning J. Tang, Qingxia Wei, Makoto Hirata, Ilkyu Han, Shu Takeda, David Kirsch, Jay Wunder, Benjamin Alman
- Organizer
  CTOS2016 Annual Meeting
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18398
[Presentation] C/EBP-β and RUNX2 cooperatively control cartilage degradation with MMP-13 as the target and HIF-α as the inducer in chondrocytes.2011
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Saito T, Mabuchi A, Sapkota BJ, Akune T, Yano F, Ikeda T, Nishida N, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
- Organizer
  33th annual meeting of the American Society for Bone and Mineral Research (ASBMR).
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] 11.Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Nakamura K, Chung UI, Kawaguchi H: Functional redundancy of GSK-α and GSK-β to control chondrocyte differentiation through phosphorylation of RelA/NF-kB p65.2011
- Author(s)
  Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  33th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] NF-κBファミリー分子RelAはADAMTS5を転写誘導して変形性関節症の発症に関与する.2011
- Author(s)
  小林寛、平田真、伊藤祥三、斎藤琢、鄭雄一、中村耕三、川口浩
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  ベイシア文化ホール、群馬県
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] メカニカルストレス負荷によるマウス実験的変形性関節症モデル2011
- Author(s)
  深井厚、斎藤琢、平田真、鄭雄一、中村耕三、川口浩
- Organizer
  第29回日本骨代謝学会(招待講演)
- Place of Presentation
  大阪国際会議場、大阪府
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] Transcriptional induction of ADAMTS5 by an NF-κΒ family member RelA/p65 in chondrocytes during osteoarthritis development.2011
- Author(s)
  Kobayashi H, Hirata M, Itoh S, Saito T, Nakamura K, Chung UI, and Kawaguchi H
- Organizer
  2011 IOF-ANZBMS.
- Place of Presentation
  Gold Coast, Australia
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] NF-κBファミリー分子RelAは軟骨細胞においてADAMTS5を転写誘導して変形性関節症の発症に関与する2011
- Author(s)
  小林寛、平田真、伊藤祥三、斎藤琢、鄭雄一、中村耕三、川口浩
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪国際会議場、大阪府
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] Functional redundancy of GSK-3α and GSK-3β to control chondrocyte differentiation through phosphorylation of RelA/NF-κB p65.2011
- Author(s)
  Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Nakamura K, Chung UI,and Kawaguchi H
- Organizer
  2011 IOF-ANZBMS
- Place of Presentation
  Gold Coast, Australia
- Data Source
  KAKENHI-PROJECT-23659710
[Presentation] al Molecular network on the C/EBP-beta axis including Runx2, MMP13, and HIF2A controls osteoarthritis development (Young In vestigator Award). 2010 World Congress on Osteoarthritis2010
- Author(s)
  Hirata M, et
- Organizer
  2010 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Brussels, Belgium
- Data Source
  KAKENHI-PROJECT-22591677
[Presentation] NF-kB member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.
- Author(s)
  Kobayashi H, Hirata M, Saito T, Ito S, Hosaka Y, Akiyama H, Chung U, Kawaguchi H
- Organizer
  ASBMR 2013, American Society for Bone and Mineral Research
- Place of Presentation
  Boltimore, USA
- Data Source
  KAKENHI-PROJECT-24592254
[Presentation] NF-kB member Rela/p65 in chondrocytes controls skeletal growth and osteoarthritis development by inhibiting chondrocyte apoptosis.
- Author(s)
  Kobayashi H, Hirata M, Saito T, Ito S, Hosaka Y, Akiyama H, Chung U, Kawaguchi H
- Organizer
  2013 Osteoarthritis Research Society International (OARSI) World Congress
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24592254
[Presentation] NF-kBファミリーメンバーRelA/p65は、軟骨細胞のアポトーシスを阻害することで、骨格形成と変形性関節症の進行を制御する
- Author(s)
  小林寛、平田真、伊藤祥三、齋藤琢、鄭雄一、中村耕三、川口浩
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24592254
[]
[]
[]
[]
[]
[]
[]

1. KAWANO Hirotaka (20345218)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Matsuda Koichi (90401257)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
3. Kawai Akira (90252965)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. SHINODA Yusuke (80456110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 乾洋 (60583119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 近藤格 (30284061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 市川仁 (30201924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 野口玲 (30779682)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 吉松有紀 (60808632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 吉田朗彦 (80574780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
11. KADONO Yuho (70401065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAKAGAWA Takumi (90338385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ISHII Takeshi (00222943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAMURA Kozo (60126133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 廣田仁聡 (30570733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 鄭雄一 (30345053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 齋藤琢 (30456107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 緒方直史 (10361495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中村卓郎 (00180373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中山タラントロバート (00365298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 竹中聡 (00588379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高阪真路 (00627119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 松本嘉寛 (10346794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 植田幸嗣 (10509110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
25. 穴澤卯圭 (20245525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 比留間徹 (20254188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 阿江啓介 (20376726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. 小林寛 (20407951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 堀内圭輔 (30327564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 河本旭哉 (30420558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 平賀博明 (30501530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 土屋弘行 (40227434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 坂本昭夫 (40335964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 朴木寛弥 (40336863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. 秋山達 (40376471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 片山琴絵 (40581195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 大隈知威 (40806189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 元井亨 (50291315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 西田佳弘 (50332698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 中川英刀 (50361621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
41. 米本司 (50506318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 馬場一郎 (60330073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 小田義直 (70291515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 末原義之 (70509405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 國定俊之 (80346428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 山田聡 (80405208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 相羽久輝 (70793834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 松原大祐 (80415554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
49. 筑紫聡 (90378109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 山口類 (90380675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 綿貫宗則 (90451575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 王谷英達 (60727965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 吉川秀樹 (60191558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 中紀文 (90601964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
55. 岡本健 (30414113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 五嶋孝博 (20272544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. 岩田慎太郎 (90549685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. 加藤元博 (40708690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. 中谷文彦 (00535320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. 角田達彦 (10273468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. 田仲和宏 (10274458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. 清茜 (30941512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
63. 小田智世 (60941549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
64. Alman Benjamin A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
65. ITO Hidemi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. TANIKAWA Chizu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
67. TAKAHASHI Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
68. NAITO Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 柏木賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
70. 松井啓隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
71. 鎌谷洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
72. 岡田随象

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
73. 石垣泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
74. SHOHAB YOUSSEFIAN

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
75. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
76. 市川美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
77. 石川光也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
78. 川口浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
79. 三木義男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
80. 城田英和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
81. 峯岸直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
82. 清水厚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
83. 村上善則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
84. 若井健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirata Makoto 平田 真

HIRATA Makoto 平田 真

Research Projects

Research Products

Co-Researchers

骨軟部腫瘍易罹患性に係る遺伝性腫瘍の全ゲノム解析に基づく包括的管理体系構築の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨軟部腫瘍全ゲノム解析データに基づく遺伝子異常の機能解析と治療標的の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of genomic mutations and screening of novel drug, based on comprehensive genomic analysis of muscloskeletal tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cartilage-specific IDH mutant mice for explication of underlying mechanism in chondrosarcoma developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

軟骨肉腫治療を目指した転写因子C/EBPβによる基質分解関連因子制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hirata Makoto 平田真

HIRATA Makoto 平田真