dairi tohru 大利徹

… Alternative Names

DAIRI Tohru 大利徹

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Researcher Number	70264679
Other IDs	https://orcid.org/0000-0002-3406-7970
External Links
Affiliation (Current)	2024: 北海道大学, 工学研究院, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 北海道大学, 工学研究院, 教授 2011 – 2015: Hokkaido University, 工学(系)研究科(研究院), 教授 2014: 北海道大学, 大学院工学研究科, 教授 2013: 北海道大学, 大学院工学研究院, 教授 2010 – 2012: 北海道大学, 大学院・工学研究院, 教授 … More 2007 – 2009: Toyama Prefectural University, Biotechnology Research Center, Associate Professor 2006: Toyama Prefectural University, Biotechnology Research Center, Associate Professor, 生物工学研究エンター, 助教授 2001 – 2006: 富山県立大学, 生物工学研究センター, 助教授 2000 – 2006: 富山県立大学, 工学部, 助教授 2001: Toyama Prefectural University, Biotechnology Research Center, Associate professor, 工学部・生物工学研究センター, 助教授 1995 – 1998: 富山県立大学, 工学部, 助教授 1997: Toyama Prefectural University, Biotechnology Research Center, Associate Professo Less
Review Section/Research Field	Principal Investigator Living organism molecular science / Science and Engineering / 応用微生物学・応用生物化学 / Biomolecular chemistry / Biological Sciences / Broad Section F / Medium-sized Section 38:Agricultural chemistry and related fields Except Principal Investigator Science and Engineering / Bioproduction chemistry/Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / 応用微生物学・応用生物化学 / Living organism molecular science
Keywords	Principal Investigator 生合成 / 放線菌 / cyclase / mevalonate pathway / ペプチドグリカン / isoprenoid / Terpentetriene / Terpentecin / ペプチドリガーゼ / メナキノン … More / 異性化 / ラッソペプチド / ペプチドエピメラーゼ / ポリグルタミン酸 / エピメラーゼ / ペプチド / シュードペプチド / furaquinocin A / prenyl diphosphate synthase / diterpene / terpentetriene / terpentecin / Streptomyces / Isoprenoid / Nonmevalonate pathway / Mevalonate pathway / Diterpene cyclase / フタロシン / futalosine / inhibitor / futalosine hydrolase / ent-copalyl diphosphate / 環化酵素 / イソプレノイド / ジテルペン / 天然有機化合物 / グルタミン酸エピメラーゼ / γ-ポリグルタミン酸 / 異性化酵素 / タンパク質 / リボソームペプチド / MurD2 / アシルキャリアタンパク質 / アクチノマイシンD / チオエステラーゼ / アミド結合 / シス不飽和結合導入機構 / 炭素鎖長制御機構 / 生合成酵素 / アミド結合形成酵素 / 酵素工学 / シス二重結合生成機構 / 炭素鎖長制御 / ポリケチド合成酵素 / 合成酵素 / 多価不飽和脂肪酸 / ケトメミシン / ATP-grasp / カルボニルメチレン / カルボニルメチレン構造 / シュードトリペプチド / ATP-grasp ligase / pimara-9 (11),15-diene / ent-copaly1 diphosphate / Actinomycetes / Actinobacteria / KS505a / pimara-9(11), 15-diene / copalyl diphosphate / brasilicardin A / pimara-9(11),15-diene / Stereptomyces / Teipentedienol diphosphate / terpentedienol diphosphate / Steptomycetes / diterpene cyclase / Terpentetreine / Streptomycetes / リボソーマルペプチド / ぺプチド抗生物質 / ペプチドライゲース / ペプチド抗生物質 / フェガノマイシン / 新規生合成経路 / タウリン / エルゴチオネイン / グルタチオン / 4-アミノ安息香酸 / フシコクシン / ポリオキシン / パキシリン / プレニルトランスフェラーゼ / 糸状菌 / インドールジテルペン / aminodeoxy futalosine / Radical SAM / ピロリ菌 / 阻害剤 / フタロシン経路 / 微生物 / 1, 4-dihydroxy-6-naphthoate / cyclic de-hypoxanthinefutalosine / de-hynoxanthine futalosine / hypoxanthine / KS-505a(longestin) / Rice / Brasilicardin A / Nocardia brasiliensis / サイクラーゼ / バイオインフォマティクス / 中間体 / 遺伝子 / 酵素 … More Except Principal Investigator 生合成 / 生物分子科学 / 天然物化学 / 生合成工学 / 合成生物学 / 生合成リデザイン / Helicobacter pylori / Streptomyces coelicolor / biosynthesis / 生合成中間体 / tautomycin / PCR / 生物分子化学 / Cambylobacter jejunj / blocked mutants / biosynthetic intermediates / vitamin K / menauumone / エリスロース / ホスホエノールピルビン酸 / メナキノン生合成経路 / Streptomyces sp. CL190 / 突然変異株 / フタロシン / ビタミンK / メナキノン / P450 oxygenase / cyclase / gene cluster / terpenoid / P450酸化酵素 / 環化酵素 / 遺伝子クラスター / テルペノイド / squarene / tetraterpene / biosynthetic intermediate / cyclization mechanism / terpene cyclase / diterpene / 非天然型トリテルペン / スクアレン-ホペン環化酵素 / アフィジコリンの環化機構 / テルペンテトリエン / ヤマブシタケ / 環化酵素遺伝子 / フシコクシン / テルペンテシン / アフィジコリン / サイアタジエン / エリナシン / フォマクチン / スクアレン / テトラテルペン / 環化機構 / テルペン環化酵素 / ジテルペン / gene disruption / polyketide / cloning / 放線菌 / 生合成遺伝子 / 遺伝子破壊 / 形質転換 / クローニング / ポリケチド / トウトマイシン / Methylaspartate Ammonia-Lyase / Phenylalanine Dehydrogenase / Leucine Dehydrogenase / Molecular Cloning / Site Directed Mutagenesis / X-ray Crystallographic Studies / Opine Dehydrogenase / Amino Acid Dehydrogenase / ロイシン脱水素酵素 / X線構造解析 / メチルアスパラギン酸アンモニアリアーゼ / フェニルアラニン脱水素酵素 / キメラ酵素 / 遺伝子クローニング / 部位特異的変異 / X線結晶構造解析 / オピン脱水素酵素 / アミノ酸脱水素酵素 / 3-Methylaspartase / Maleate hydratase / D-Malic Acid / Maleic Acid / Lyase / マレートスドラターゼ / 3-メチルアスパルターゼ / マレートヒドラターゼ / Dーリンゴ酸 / マレイン酸 / リアーゼ / ゲノムマイニング / Xanthomonas / パラアミノ安息香酸 / Thaumarchaeota / ammonia-oxidizing / Chlamydia / Nitrosomonas / folate / para-aminobenzoic acid / 偏性細胞内寄生菌 / アンモニア酸化菌 / クラミジア / ニトロソモナス / アミノ安息香酸 / 葉酸 / 化学酵素合成 / 大腸菌 / ペプチド合成酵素 / 天然物 / ゲノム / 抗腫瘍性物質 / 抗生物質 / 二次代謝産物 / メタボローム / バイオインフォマティクス / 物質生産 / ゲノム情報 Less

Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.Principal Investigator
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section F
- Research Institution
  Hokkaido University
Dissecting reaction mechanisms of novel peptide epimerasesPrincipal Investigator
- Principal Investigator
  
  Dairi Tohru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Hokkaido University
Redesigning Biosynthetic Machineries (Project Team)
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Studies on biosynthetic machinery of biologically active natural productsPrincipal Investigator
- Principal Investigator
  
  Dairi Tohru
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Redesigning Biosynthetic Machineries (International Activity Support Team)
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Biosynthesis of the Carbonylmethylene Structure Found in a Class of Pseudotripeptides, KetomemicinsPrincipal Investigator
- Principal Investigator
  
  Dairi Tohru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Peptide synthesis cooperatively achieved by peptide ligase and ribosomesPrincipal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Hokkaido University
Estimation of an alternative biosynthetic pathway for co-factors by close investigation of genome databases.Principal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Study on a novel folate biosynthesis pathway on micoorganism
- Principal Investigator
  
  SATOH Yasuharu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Studies on biosynthetic machineries for cyclic terpenoids and nucleoside antibioticsPrincipal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
微生物が生産する環状テルペノイド生合成マシナリーの解明と再構築Principal Investigator
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Biosynthetic machinery: Deciphering and regulating the system for creating structural diversity of baioactive metabolites
- Principal Investigator
  
  OIKAWA Hideaki
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Screening of natural products which inhibits a new menaquinone biosynthetic pathwayPrincipal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
病原菌が持つメナキノン新規生合成経路の全容解明と経路特異的阻害剤の探索Principal Investigator
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Prefectural University
Studies on diterpene cyclases found in eubacteriaPrincipal Investigator
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Toyama Prefectural University
病原菌が持つメナキノン新規生合成経路の全容解明と経路特異的阻害剤の探索Principal Investigator
- Principal Investigator
  
  大利徹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Toyama Prefectural University
Studies on a new biosynthetic pathway for menaquinone (vitamin K)
- Principal Investigator
  
  SETO Haruo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Tokyo University of Agriculture
Studies on production and improvement of terpenoids using biosynthetic gene cluster in fungi and plants.
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Studies on isoprenoid biosynthetic genes isolated from prokaryotesPrincipal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Toyama Prefectural University
Studies on diterpene cydases found in actinomycetes.Principal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Toyama Prefectural University
Scientific research on elucidation of terpene-cyclic reactions in the biosynthesis of bioactive microbial terpenoids.
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Studies on the biosynthesis of terpenoids produced by streptomycetes.Principal Investigator
- Principal Investigator
  
  DAIRI Tohru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Toyama Prefectural University
Reaction Mechanisms and Application of New Bacterial Enzymes
- Principal Investigator
  
  ASANO Yasuhisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Toyama Prefectural University
Cloning and Analysis of Tautomycin Biosynthetic Genes
- Principal Investigator
  
  UBUKATA Makoto
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Toyama Prefectural University
Development of Novel Lyases and Their Application to the Synthesis of Optically Active Compounds
- Principal Investigator
  
  ASANO Yasuhisa
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Toyama Prefectural University

[Book] 脂質・脂肪酸関連物質の使いこなし方－素材開発・機能創生・応用技術－2020
- Author(s)
  相川　達郎、大利　徹（分担執筆）
- Total Pages
  618
- Publisher
  テクノシステム
- ISBN
  9784924728868
- Data Source
  KAKENHI-PLANNED-16H06452
[Book] ビタミンKと疾患2014
- Author(s)
  大利　徹（分担執筆）
- Total Pages
  287
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PLANNED-23108101
[Book] Isoprenoid Synthesis in Plants and Microorganisms2013
- Author(s)
  Tohru Dairi（分担執筆）
- Total Pages
  493
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22310139
[Book] Methods in Enzymol2012
- Author(s)
  T. Dairi
- Publisher
  Menaquinone biosyntheses in microorganisms
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Ergothioneine production by Corynebacterium glutamicum harboring heterologous biosynthesis pathways2023
- Author(s)
  Hirasawa Takashi、Shimoyamada Yuki、Tachikawa Yukio、Satoh Yasuharu、Kawano Yusuke、Dairi Tohru、Ohtsu Iwao
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 135 Issue: 1 Pages: 25-33
- DOI
  10.1016/j.jbiosc.2022.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04976
[Journal Article] Biosynthetic Gene Cluster of Linaridin Peptides Contains Epimerase Gene2022
- Author(s)
  Xiao Wanlu、Satoh Yasuharu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  ChemBioChem
  
  Volume: 23 Issue: 12
- DOI
  10.1002/cbic.202100705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04976
[Journal Article] First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria2022
- Author(s)
  Takeuchi Yamato、Ushimaru Kazunori、Kaneda Kohei、Maruyama Chitose、Ito Takashi、Yamanaka Kazuya、Ogasawara Yasushi、Katano Hajime、Kato Yasuo、Dairi Tohru、Hamano Yoshimitsu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1132-1132
- DOI
  10.1038/s42003-022-04110-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05403, KAKENHI-PLANNED-22H05122, KAKENHI-PROJECT-22H04976
[Journal Article] Identification of the peptide epimerase MslH responsible for d-amino acid introduction at the C-terminus of ribosomal peptides2021
- Author(s)
  Feng Zhi、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 7 Pages: 2567-2574
- DOI
  10.1039/d0sc06308h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18H03937
[Journal Article] Identification of pulvomycin as an inhibitor of the futalosine pathway2021
- Author(s)
  Ogasawara Yasushi、Umetsu Shuhei、Inahashi Yuki、Nonaka Kenichi、Dairi Tohru
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 74 Issue: 11 Pages: 825-829
- DOI
  10.1038/s41429-021-00465-8
- NAID
  120007193348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] Flavonoids from Woodfordia fruticosa as potential SmltD inhibitors in the alternative biosynthetic pathway of peptidoglycan2021
- Author(s)
  Lee Yuan-E、Kodama Takeshi、Win Nwet Nwet、Ki Dae-Won、Hoang Nhat Nam、Wong Chin Piow、Lae Khine Zar Wynn、Ngwe Hla、Dairi Tohru、Morita Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 36 Pages: 127787-127787
- DOI
  10.1016/j.bmcl.2021.127787
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16025, KAKENHI-PLANNED-16H06452, KAKENHI-PUBLICLY-19H04649, KAKENHI-PROJECT-18H03937
[Journal Article] Discovery of an alternative pathway of peptidoglycan biosynthesis: A new target for pathway specific inhibitors2021
- Author(s)
  Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Journal of Industrial Microbiology and Biotechnology
  
  Volume: 48 Issue: 9-10
- DOI
  10.1093/jimb/kuab038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] Identification of Cyclopropane Formation in the Biosyntheses of Hormaomycins and Belactosins: Sequential Nitration and Cyclopropanation by Metalloenzymes2021
- Author(s)
  Li Xiaojun、Shimaya Ryo、Dairi Tohru、Chang Wei‐chen、Ogasawara Yasushi
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 61 Issue: 7
- DOI
  10.1002/anie.202113189
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937, KAKENHI-PROJECT-22H04976
[Journal Article] Recent advances in functional analysis of polyunsaturated fatty acid synthases2020
- Author(s)
  Hayashi Shohei、Satoh Yasuharu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 59 Pages: 30-36
- DOI
  10.1016/j.cbpa.2020.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18H03937
[Journal Article] High Production of Ergothioneine in Escherichia coli using the Sulfoxide Synthase from Methylobacterium strains2020
- Author(s)
  Kamide Tomoyuki、Takusagawa Shun、Tanaka Naoyuki、Ogasawara Yasushi、Kawano Yusuke、Ohtsu Iwao、Satoh Yasuharu、Dairi Tohru
- Journal Title
  
  Journal of Agricultural and Food Chemistry
  
  Volume: 68 Issue: 23 Pages: 6390-6394
- DOI
  10.1021/acs.jafc.0c01846
- NAID
  120007044519
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18H03937, KAKENHI-PLANNED-19H05687
[Journal Article] 抗酸化物質エルゴチオネインの組換え微生物による発酵生産2020
- Author(s)
  佐藤康治, 大津巌生, 大利徹
- Journal Title
  
  科学と工業
  
  Volume: 94 Pages: 40-45
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Off-Loading Mechanism of Products in Polyunsaturated Fatty Acid Synthases2020
- Author(s)
  Hayashi Shohei、Ogasawara Yasushi、Satoh Yasuharu、Maruyama Chitose、Hamano Yoshimitsu、Dairi Tohru
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 15 Issue: 3 Pages: 651-656
- DOI
  10.1021/acschembio.0c00075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18J10174
[Journal Article] Control Mechanism for cis Double-Bond Formation by Polyunsaturated Fatty-Acid Synthases2019
- Author(s)
  Hayashi Shohei、Satoh Yasuharu、Ogasawara Yasushi、Maruyama Chitose、Hamano Yoshimitsu、Ujihara Tetsuro、Dairi Tohru
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 58 Issue: 8 Pages: 2326-2330
- DOI
  10.1002/anie.201812623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18J10174, KAKENHI-PROJECT-16K06864
[Journal Article] Gram-scale fermentative production of ergothioneine driven by overproduction of cysteine in Escherichia coli2019
- Author(s)
  Tanaka Naoyuki、Kawano Yusuke、Satoh Yasuharu、Dairi Tohru、Ohtsu Iwao
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 853-853
- DOI
  10.1038/s41598-018-38382-w
- NAID
  120007128198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0028, KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-16K06864, KAKENHI-PROJECT-16K18675
[Journal Article] Identification of actinomycin D as a specific inhibitor of the alternative pathway of peptidoglycan biosynthesis2019
- Author(s)
  Ogasawara Yasushi、Shimizu Yohei、Sato Yohei、Yoneda Tomoki、Inokuma Yasuhide、Dairi Tohru
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 73 Issue: 2 Pages: 125-127
- DOI
  10.1038/s41429-019-0252-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-17H04872
[Journal Article] Involvement of Peptide Epimerization in Poly-γ-glutamic Acid Biosynthesis2019
- Author(s)
  Ogasawara Yasushi、Shigematsu Mayuko、Sato Shota、Kato Hinata、Dairi Tohru
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 11 Pages: 3972-3975
- DOI
  10.1021/acs.orglett.9b01121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] Subtle Control of Carbon Chain Length in Polyunsaturated Fatty Acid Synthases2019
- Author(s)
  Naka Mai、Ikeuchi Kenshin、Hayashi Shohei、Satoh Yasuharu、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 14 Issue: 12 Pages: 2553-2556
- DOI
  10.1021/acschembio.9b00803
- NAID
  120006937028
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18J10174
[Journal Article] 海洋微生物における多価不飽和脂肪酸生合成酵素の解析と応用2019
- Author(s)
  林祥平, 小笠原泰志, 佐藤康治, 大利徹
- Journal Title
  
  B & I
  
  Volume: 77 Pages: 448-452
- NAID
  40022073292
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Amino Acid Residues Recognizing Isomeric Glutamate Substrates in UDP-N-acetylmuramic acid-l-alanine-glutamate Synthetases2019
- Author(s)
  Feng Ruoyin、Satoh Yasuharu、Morita Hiroyuki、Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 14 Issue: 5 Pages: 975-978
- DOI
  10.1021/acschembio.9b00159
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PUBLICLY-19H04649
[Journal Article] Control mechanism for carbon chain length in polyunsaturated fatty acid synthases2019
- Author(s)
  Dairi Tohru、Hayashi Shohei、Naka Mai、Ikeuchi Kenshin、Ohtsuka Makoto、Kobayashi Kota、Satoh Yasuharu、Ogasawara Yasushi、Maruyama Chitose、Hamano Yoshimitsu、Ujihara Tetsuro
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 58 Issue: 20 Pages: 6605-6610
- DOI
  10.1002/anie.201900771
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-18J10174, KAKENHI-PROJECT-16K06864
[Journal Article] In vitro characterization of MitE and MitB: Formation of N-acetylglucosaminyl-3-amino-5-hydroxybenzoyl-MmcB as a key intermediate in the biosynthesis of antitumor antibiotic mitomycins2019
- Author(s)
  Ogasawara Yasushi、Nakagawa Yo、Maruyama Chitose、Hamano Yoshimitsu、Dairi Tohru
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 29 Issue: 16 Pages: 2076-2078
- DOI
  10.1016/j.bmcl.2019.07.009
- NAID
  120007132051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] 放線菌が生み出した疑似ペプチド化合物-疑似ペプチド（ケトメミシン）がもつカルボニルメチレンの生合成を解明-2018
- Author(s)
  小笠原泰志、大利徹
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 76-78
- NAID
  130007563335
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Total biosynthesis of brassicicenes: Identification of a key enzyme for skeletal diversification2018
- Author(s)
  Tazawa, A.; Ye, Y.; Ozaki, T.; Liu, C.; Ogasawara, Y.; Dairi, T.; Higuchi, Y.; Kato, N.; Gomi, K.; Minami, A.; Oikawa, H.
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Issue: 19 Pages: 6178-6182
- DOI
  10.1021/acs.orglett.8b02654
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PLANNED-16H06452, KAKENHI-PUBLICLY-17H05425
[Journal Article] Functional analysis of methyltransferases participating in streptothricin-related antibiotic biosynthesis2018
- Author(s)
  Niikura Haruka、Maruyama Chitose、Ogasawara Yasushi、Shin-ya Kazuo、Dairi Tohru、Hamano Yoshimitsu
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 125 Issue: 2 Pages: 148-154
- DOI
  10.1016/j.jbiosc.2017.09.004
- NAID
  40021471176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PLANNED-16H06452, KAKENHI-PLANNED-16H06445
[Journal Article] Peptide Epimerization Machineries Found in Microorganisms2018
- Author(s)
  Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Front. Microbiol.
  
  Volume: 9 Pages: 1-9
- DOI
  10.3389/fmicb.2018.00156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PROJECT-16K18692, KAKENHI-PROJECT-18H03937
[Journal Article] 創薬を志向した微生物の生合成工学2018
- Author(s)
  大利徹
- Journal Title
  
  The Japanese Journal of Antibiotics
  
  Volume: 71-1 Pages: 1-11
- NAID
  40021485948
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] 創薬を志向した微生物の生合成工学2018
- Author(s)
  大利徹
- Journal Title
  
  The Japanese Journal of Antibiot.
  
  Volume: 71 Pages: 1-11
- NAID
  40021485948
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Searching for potent and specific antibiotics against pathogenic Helicobacter and Campylobacter strains2018
- Author(s)
  Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Journal of Industrial Microbiology & Biotechnology
  
  Volume: 46 Issue: 3-4 Pages: 409-414
- DOI
  10.1007/s10295-018-2108-3
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Heterologous and High Production of Ergothioneine in Escherichia coli2018
- Author(s)
  Osawa Ryo、Kamide Tomoyuki、Satoh Yasuharu、Kawano Yusuke、Ohtsu Iwao、Dairi Tohru
- Journal Title
  
  Journal of Agricultural and Food Chemistry
  
  Volume: 66 Issue: 5 Pages: 1191-1196
- DOI
  10.1021/acs.jafc.7b04924
- NAID
  120007134442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-16K06864
[Journal Article] Aplasmomycin and boromycin are specific inhibitors of the futalosine pathway2018
- Author(s)
  Shimizu Yohei、Ogasawara Yasushi、Matsumoto Atsuko、Dairi Tohru
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 71 Issue: 11 Pages: 968-970
- DOI
  10.1038/s41429-018-0087-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Ergothioneine production with Aspergillus oryzae2018
- Author(s)
  Takusagawa Shun、Satoh Yasuharu、Ohtsu Iwao、Dairi Tohru
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 83 Issue: 1 Pages: 181-184
- DOI
  10.1080/09168451.2018.1527210
- NAID
  120007133324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0028, KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-16K06864
[Journal Article] Novel enzymology in futalosine-dependent menaquinone biosynthesis2018
- Author(s)
  Joshi Sumedh、Fedoseyenko Dmytro、Mahanta Nilkamal、Manion Hannah、Naseem Saad、Dairi Tohru、Begley Tadhg P
- Journal Title
  
  Current Opinion in Chemical Biology
  
  Volume: 47 Pages: 134-141
- DOI
  10.1016/j.cbpa.2018.09.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Enzymatic formation of a skipped methyl-substituted octaprenyl side chain of longestin (KS-505a): Involvement of homo-IPP as a common extender unit2018
- Author(s)
  Ozaki Taro、Shinde Sandip S.、Gao Lei、Okuizumi Ryo、Liu Chengwei、Ogasawara Yasushi、Lei Xiaoguang、Dairi Tohru、Minami Atsushi、Oikawa Hideaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 22 Pages: 6629-6632
- DOI
  10.1002/anie.201802116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06446, KAKENHI-PROJECT-15H01835, KAKENHI-PLANNED-16H06452, KAKENHI-PUBLICLY-17H05425
[Journal Article] Biosynthetic Gene Cluster of a D-Tryptophan-Containing Lasso Peptide, MS-2712018
- Author(s)
  Feng Zhi、Ogasawara Yasushi、Nomura Satoshi、Dairi Tohru
- Journal Title
  
  ChemBioChem
  
  Volume: 19 Issue: 19 Pages: 2045-2048
- DOI
  10.1002/cbic.201800315
- NAID
  120006727595
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05449, KAKENHI-PROJECT-18H03937
[Journal Article] 放線菌が生み出した疑似ペプチド化合物-疑似ペプチド（ケトメミシン）がもつカルボニルメチレンの生合成を解明-2018
- Author(s)
  小笠原泰志, 大利徹
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 76-78
- NAID
  130007563335
- Data Source
  KAKENHI-PROJECT-15H03110
[Journal Article] 細菌ペプチドグリカンの新規生合成機構2017
- Author(s)
  佐藤康治, 馮若茵, 大利徹
- Journal Title
  
  B & I
  
  Volume: 75 Pages: 422-423
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Bioengineering utilizing microorganisms2017
- Author(s)
  大利　徹
- Journal Title
  
  生化学
  
  Volume: 89 Issue: 2 Pages: 221-229
- DOI
  10.14952/SEIKAGAKU.2017.890221
- NAID
  40021203291
- ISSN
  0037-1017
- Year and Date
  2017-04-25
- Language
  Japanese
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Biosynthesis of the Carbonylmethylene Structure Found in the Ketomemicin Class of Pseudotripeptides2017
- Author(s)
  J. Kawata, T. Naoe, Y. Ogasawara, and T. Dairi
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 56 Issue: 8 Pages: 2026-2029
- DOI
  10.1002/anie.201611005
- NAID
  120006383813
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PROJECT-16K18692
[Journal Article] Biosynthesis of Oligopeptides Using ATP-Grasp Enzymes2017
- Author(s)
  Ogasawara Yasushi、Dairi Tohru
- Journal Title
  
  Chemistry
  
  Volume: 23 Issue: 45 Pages: 10714-10724
- DOI
  10.1002/chem.201700674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PROJECT-16K18692
[Journal Article] N-Phenylacetylation and Nonribosomal Peptide Synthetases with Substrate Promiscuity for Biosynthesis of Heptapeptide Variants, JBIR-78 and JBIR-952017
- Author(s)
  Takeda Kunpei、Kemmoku Kohei、Satoh Yasuharu、Ogasawara Yasushi、Shin-ya Kazuo、Dairi Tohru
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 12 Issue: 7 Pages: 1813-1819
- DOI
  10.1021/acschembio.7b00314
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Identification of tirandamycins as specific inhibitors of the futalosine pathway2017
- Author(s)
  Ogasawara Yasushi、Kondo Kensuke、Ikeda Ayumi、Harada Rikako、Dairi Tohru
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 6 Pages: 798-800
- DOI
  10.1038/ja.2017.22
- NAID
  120006374989
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] A Glycopeptidyl-Glutamate Epimerase for Bacterial Peptidoglycan Biosynthesis2017
- Author(s)
  Feng Ruoyin、Satoh Yasuharu、Ogasawara Yasushi、Yoshimura Tohru、Dairi Tohru
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 139 Issue: 12 Pages: 4243-4245
- DOI
  10.1021/jacs.7b01221
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06452
[Journal Article] Structure and activity relationships of the anti-Mycobacterium antibiotics resorcinomycin and pheganomycin2016
- Author(s)
  Y. Ogasawara, K. Ooya, M. Fujimori, M. Noike, and T. Dairi
- Journal Title
  
  J. Antibiot.
  
  Volume: 69 Issue: 2 Pages: 119-120
- DOI
  10.1038/ja.2015.88
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03110
[Journal Article] Enhanced production of polyunsaturated fatty acids by enzyme engineering of tandem acyl carrier proteins2016
- Author(s)
  S. Hayashi, Y. Satoh, T. Ujihara, Y. Takata, T. Dairi
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 35441-35441
- DOI
  10.1038/srep35441
- NAID
  120005890050
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06452, KAKENHI-PROJECT-16K06864
[Journal Article] Exploring peptide ligase orthologs in actinobacteria-discovery of pseudopeptide natural products, ketomemicins-2016
- Author(s)
  Y. Ogasawara, J. Kawata, M. Noike, Y. Satoh, K. Furihata, and T. Dairi
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 11 Issue: 6 Pages: 1686-1692
- DOI
  10.1021/acschembio.6b00046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03110
[Journal Article] Characterization of three amidinotransferases involved in the biosynthesis of ketomemicins2016
- Author(s)
  Y. Ogasawara, M. Fujimori, J. Kawata, and T. Dairi
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Issue: 15 Pages: 3662-3664
- DOI
  10.1016/j.bmcl.2016.05.090
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03110, KAKENHI-PROJECT-16K18692
[Journal Article] A Peptide Ligase and the Ribosome Cooperate to Synthesize the Peptide Pheganomycin2015
- Author(s)
  M. Noike, T. Matsui, K. Ooya, I. Sasaki, S. Ohtaki, Y. Hamano, C. Maruyama, J. Ishikawa, Y. Satoh, H. Ito, H. Morita, and T. Dairi
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 11 Pages: 71-71
- NAID
  120005619608
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22108001
[Journal Article] A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin.2015
- Author(s)
  Noike, M., Matsui, T., Ooya, K., Sasaki, I., Ohtaki, S., Hamano, Y., Maruyama, C., Ishikawa, J., Satoh, Y., Ito, H., Morita, H. and Dairi T.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 11 Issue: 1 Pages: 71-76
- DOI
  10.1038/nchembio.1697
- NAID
  120005619608
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22108010, KAKENHI-PLANNED-23108101, KAKENHI-PROJECT-24770088, KAKENHI-PUBLICLY-25108710, KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-25560397, KAKENHI-PROJECT-26282210
[Journal Article] ペプチド末端を保護する新たな酵素2015
- Author(s)
  大利　徹
- Journal Title
  
  化学
  
  Volume: 70 Pages: 40-44
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25560397
[Journal Article] ペプチド末端を保護する新たな酵素2015
- Author(s)
  大利　徹
- Journal Title
  
  化学
  
  Volume: 70 Pages: 40-44
- Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] Identification and analysis of the resorcinomycin biosynthetic gene cluster.2015
- Author(s)
  K. Ooya, Y. Ogasawara, M. Noike, and T. Dairi
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 79 Issue: 11 Pages: 1833-1837
- DOI
  10.1080/09168451.2015.1050992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03110
[Journal Article] Functional analysis of a prenyltransferase gene (paxD) in the paxilline biosynthetic gene cluster.2014
- Author(s)
  C. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi.
- Journal Title
  
  Appl. Microbiol. Biotech.
  
  Volume: 99 Issue: 1 Pages: 199-206
- DOI
  10.1007/s00253-013-4834-9
- NAID
  120005522325
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] New gene responsible for para-aminobenzoate biosynthesis2014
- Author(s)
  Satoh, Y., Kuratsu, M., Kobayashi, D., Dairi, T.
- Journal Title
  
  J. Biosci. Bioeng
  
  Volume: 117(2) Issue: 2 Pages: 178-183
- DOI
  10.1016/j.jbiosc.2013.07.013
- NAID
  110010039563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710239, KAKENHI-PROJECT-25560397
[Journal Article] A Fungal Prenyltransferase Catalyzes the Regular Di-prenylation at Positions 20 and 21 of Paxilline.2014
- Author(s)
  C. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi.
- Journal Title
  
  Biosci. Biotech. Biochem.
  
  Volume: 78 Issue: 3 Pages: 448-454
- DOI
  10.1080/09168451.2014.882759
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] Rapid reconstitution of biosynthetic machinery for fungal metabolites in Aspergillus oryzae: Total biosynthesis of aflatrem2014
- Author(s)
  K. Tagami, A. Minami, R. Fujii, C. W. Liu, K. Gomi, T. Dairi, H. Oikawa
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 14 Pages: 2076-2076
- DOI
  10.1002/cbic.201402195
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-22108007, KAKENHI-PLANNED-23108101
[Journal Article] CcpAx is a new member of the cellulose synthase complex (terminal complex) in Acetobacter xylinum2013
- Author(s)
  N. Sunagawa, T. Fujiwara, T. Yoda, D. Shimura, M. Sakai, S. Kawano, Y. Satoh, M. Yao, K. Tajima, and T. Dairi
- Journal Title
  
  J. Biosci. Bioeng
  
  Volume: in press Issue: 6 Pages: 607-612
- DOI
  10.1016/j.jbiosc.2012.12.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139, KAKENHI-PROJECT-25560397
[Journal Article] In vitro reconstitution of the radical SAM enzyme MqnC involved in the biosynthesis of futalosine-derived menaquinone.2013
- Author(s)
  LE. Cooper, D. Fedoseyenko, SH. Abdelwahed, SH. Kim, T. Dairi, and TP. Begley.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Issue: 27 Pages: 4592-4594
- DOI
  10.1021/bi400498d
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] Reconstitution of biosynthetic machinery for indole-diterpene paxilline in Aspergillus oryzae.2013
- Author(s)
  K. Tagami, C. Liu, A. Minami, M. Noike, T. Isaka, S. Fueki, Y. Shichijo, H. Toshima, K, T. Dairi, and H. Oikawa.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 4 Pages: 1260-1263
- DOI
  10.1021/ja3116636
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23108101, KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-22108007
[Journal Article] Regiospecificities and prenylation mode specificities of the fungal indole diterpene prenyltransferases AtmD and PaxD2013
- Author(s)
  C. Liu, M. Noike, A. Minami, H. Oikawa, T. Dairi
- Journal Title
  
  Appl. Environ. Microbiol.
  
  Volume: 79 Issue: 23 Pages: 7298-7304
- DOI
  10.1128/aem.02496-13
- NAID
  120005451569
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-23108101
[Journal Article] CcpAx is a new member of the cellulose synthase complex (terminal complex) in Acetobacter xylinum2013
- Author(s)
  N. Sunagawa, T. Fujiwara, T. Yoda, D.Shimura, M. Sakai, S. Kawano, Y. Satoh, M. Yao, K. Tajima, and T. Dairi
- Journal Title
  
  J. Biosci. Bioeng
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme2013
- Author(s)
  N. Mahanta, D. Fedoseyenko, T. Dairi, and T. P. Begley
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 41 Pages: 15318-15321
- DOI
  10.1021/ja408594p
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-23108101
[Journal Article] Cellulose production by Enterobacter sp. CJF-002 and identification of genes for cellulose biosynthesis2012
- Author(s)
  N. Sunagawa, K. Tajima, M. Hosoda, S. Kawano, Y. Satoh, M. Yao, T. Dairi
- Journal Title
  
  Cellulose
  
  Volume: 19 Issue: 6 Pages: 1989-2001
- DOI
  10.1007/s10570-012-9777-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Menaquinone biosyntheses in microorganisms.2012
- Author(s)
  Dairi T.
- Journal Title
  
  Methods Enzymol
  
  Volume: 515 Pages: 107-122
- DOI
  10.1016/b978-0-12-394290-6.00006-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Molecular breeding of a fungus producing a precursor diterpene suitable for semi-synthesis by dissection of the biosynthetic machinery2012
- Author(s)
  M. Noike, Y. Ono, Y. Araki, R. Tanio, Y. Higuchi, H. Nitta, Y. Hamano, T. Toyomasu, T. Sassa, N. Kato, and T. Dairi
- Journal Title
  
  PLoS ONE
  
  Volume: - Issue: 8 Pages: e42090-e42090
- DOI
  10.1371/journal.pone.0042090
- NAID
  120004689045
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] An Enzyme Catalyzing O-Prenylation of the Glucose Moiety of Fusicoccin A, a Diterpene Glucoside Produced by Fungus2012
- Author(s)
  M.Noike, C.Liu, Y.Ono, Y.Hamano, T.Toyomasu, T.Sassa, N.Kato, T.Dairi
- Journal Title
  
  ChemBioChem
  
  Volume: 13 Issue: 4 Pages: 566-573
- DOI
  10.1002/cbic.201100725
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23108101
[Journal Article] Diversity of the early step of the futalosine pathway.2011
- Author(s)
  C.Arakawa, K.Furihata, T.Hiratsuka, N.Itoh, H.Seto, T.Dairi
- Journal Title
  
  Antimicrob. Agents Chemother.
  
  Volume: 55 Pages: 913-916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] 微生物におけるビタミンK生合成の分子機構と生物学的意義2011
- Author(s)
  大利徹
- Journal Title
  
  腎と代謝
  
  Volume: 24巻 Pages: 179-186
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Diversity of the early step of the futalosine pathway.2011
- Author(s)
  C. Arakawa, K. Furihata, T. Hiratsuka, N.Itoh, H. Seto, and T. Dairi
- Journal Title
  
  Antimicrob Agents Chemother.
  
  Volume: 55 Pages: 913-916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Convergent strategies in biosynthesis.2011
- Author(s)
  T. Dairi, T. Kuzuyama, M. Nishiyama, and Fujii I.
- Journal Title
  
  Nat. Prod. Rep.
  
  Volume: 28 (6) Pages: 1054-1086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Branched fatty acids inhibit the biosynthesis of menaquinone in Helicobacter pylori.2011
- Author(s)
  R.Tanaka, T.Kunisada, N.Kushida, K.Yamada, S.Ikeda, M.Noike, Y.Ono, N.Itoh, H.Takami, H.Seto, T.Dairi
- Journal Title
  
  J.Antibiot.
  
  Volume: 64 Pages: 151-153
- NAID
  10030637951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Dioxygenases, key enzymes to determine the aglycon structures of fusicoccin and brassicicene, diterpene compounds produced by fungi2011
- Author(s)
  Y.Ono, A.Minami, M.Noike, Y.Higuchi, T.Toyomasu, T.Sassa, N.Kato, T.Dairi
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: Vol.133 Issue: 8 Pages: 18134-18137
- DOI
  10.1021/ja107785u
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108002, KAKENHI-PLANNED-23108101
[Journal Article] Synthesis of (±)-cyclic de-hypoxanthine futalosine, the biosynthetic intermediate in an alternative biosynthetic pathway for menaquinones2011
- Author(s)
  A.Yajima, S.Kouno, M.Mogi, R.Katsuta, T.Dairi, H.Seto, T.Nukada
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 52 Issue: 38 Pages: 4934-4937
- DOI
  10.1016/j.tetlet.2011.07.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation2011
- Author(s)
  S. Takahashi, A. Toyoda, Y. Sekiyama, H.Takagi, T. Nogawa, M. Uramoto, R. Suzuki, H. Koshino, T. Kumano, S. Panthee, T. Dairi, J. Ishikawa, H. Ikeda, Y. Sakaki, and H. Osada
- Journal Title
  
  Nat. Chem. Biol.
  
  Volume: 7 Pages: 461-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Enzymatic polymerization of 2-hydroxyalkanoates: copolymerization of 2-hydroxybutyrate by wild-type class I PHA synthase.2011
- Author(s)
  X. Han, Y. Satoh, T. Satoh, T. Kakuchi, K.Matsumoto, S. Taguchi, T. Dairi, M. Munekata, and K. Tajima
- Journal Title
  
  Appl. Microbiol. Biotech.
  
  Volume: 92 Pages: 509-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Convergent strategies in biosynthesis2011
- Author(s)
  T.Dairi, T.Kuzuyama, M.Nishiyama, Fujii I
- Journal Title
  
  Nat.Prod.Rep.
  
  Volume: 28 Issue: 6 Pages: 1054-1086
- DOI
  10.1039/c0np00047g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139, KAKENHI-PUBLICLY-23108524
[Journal Article] Isolation of a Thermotolerant Bacterium Producing Medium-chain-length Polyhydroxyalkanoate2011
- Author(s)
  Y. Satoh, K. Tajima, S. Nakamoto, H.Xuerong, T. Matsushima, T. Ohshima, S. Kawano, T. Erata, T. Dairi, and M. Munekata
- Journal Title
  
  J. Appl. Microbiol.
  
  Volume: 111 Pages: 811-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Synthesis of (±)-cyclic de-hypoxanthine futalosine, the biosynthetic intermediate in an alternative biosynthetic pathway for menaquinones.2011
- Author(s)
  A. Yajima, S. Kouno, M. Mogi, R. Katsuta, T. Dairi, H. Seto, and T. Nukada
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 52 Pages: 4934-4937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] Analysis of the Lactobacillus metabolic pathway.2010
- Author(s)
  M.Kuratsu, Y.Hamano, T.Dairi
- Journal Title
  
  Appl.Environ.Microbiol.
  
  Volume: 76 Pages: 7299-7301
- NAID
  120002973851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310139
[Journal Article] An alternative menaquinone biosynthetic pathway operating in microorga nisms : an attractive target for drug discovery to pathogenic Helicobacter and Chlamydia strains.2009
- Author(s)
  T.Dairi
- Journal Title
  
  J.Antibiot. 62
  
  Pages: 347-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20018023
[Journal Article] 創薬ターゲットとしてのメナキノン新規生合成経路2009
- Author(s)
  大利徹
- Journal Title
  
  ファルマシア 45
  
  Pages: 870-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20018023
[Journal Article] Studies on a new biosynthetic pathway for menaquinone2008
- Author(s)
  H. Seto, Y. Jinnai, T. Dairi
- Journal Title
  
  J. Amer. Chem. Soc. 130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380075
[Journal Article] Comparison of theEnzymatic Properties of ent-CopalylDiphosphate Synthases in theBiosynthesis of Phytoalexins andGibberellins in Rice2008
- Author(s)
  Y. Hayashi, T. Toyomasu, Y. Hirose, Y.Onodera, W. Mitsuhashi, H. Yamane, T.Sassa, and T. Dairi
- Journal Title
  
  Biosci. Biotech.Biochem 72
  
  Pages: 523-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510220
[Journal Article] Cloning of the Gene ClusterResponsible for the Biosynthesis ofBrasilicardin A2008
- Author(s)
  Y. Hayashi, N. Matsuura, H. Toshima, N.Itoh, J. Ishikawa, Y. Mikami, and T.Dairi
- Journal Title
  
  a Unique Diterpenoid.J. Antibiot 61
  
  Pages: 164-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510220
[Journal Article] Studies on a new biosynthetic pathway for menaquinone2008
- Author(s)
  H., Seto, Y., Jinnai, T., Hiratsuka, M., Fukawa, K., Furihata, N., Itoh, T., Dairi
- Journal Title
  
  J. Amer. Chem. Soc 130
  
  Pages: 5614-5615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380075
[Journal Article] Studies on a new biosynthetic pathway for menaquinone2008
- Author(s)
  H. Seto, Y. Jinnai, T. Dairi
- Journal Title
  
  J.Arner.Chem.Soc. 130
  
  Pages: 5614-5615
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380075
[Journal Article] Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi2007
- Author(s)
  T.Toyomasu, M.Tsukahara, A.Kaneko, R.Niida, W.Mitsuhashi, T.Dairi, N.Kato, T.Sassa
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A. 104
  
  Pages: 3084-3088
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi2007
- Author(s)
  T.Toyomasu, M.Tsukahara, A.Kaneko, R.Niida, W.Mitsuhashi, T.Dairi, N.Kato, T.Sassa
- Journal Title
  
  Proc.Natl.Acad.Sci.USA vol.104, No.9
  
  Pages: 3084-3088
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Analysis of Eubacterial ent-Copalyl Diphosphate Synthase and Pimara-9(11), 15-diene Synthase with Unique Primary Sequences.2007
- Author(s)
  C.Ikeda, Y.Hayashi, N.Itoh, H.Seto, T.Dairi
- Journal Title
  
  J. Biochem. 141
  
  Pages: 37-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Analysis of Eubacterial ent-Copalyl Diphosphate Synthase and Pimara-9(11),15-diene Synthase with Unique Primary Sequences.2007
- Author(s)
  C.Ikeda, Y.Hayashi, N.Itoh, H.Seto, T.Dairi
- Journal Title
  
  J.Biochem. vol.141
  
  Pages: 37-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] A Comparative Analysis of the Sugar Phosphate Cyclase Superfamily Involved in Primary and Secondary Metabolism.2007
- Author(s)
  X.Wu, P.M.Flatt, O.Schlorke, A.Zeeck, T.Dairi, T.Mahmud
- Journal Title
  
  ChemBioChem. vol.8, Issiue 2
  
  Pages: 239-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] A Comparative Analysis of the Sugar Phosphate Cyclase Superfamily Involved in Primary and Secondary Metabolism.2007
- Author(s)
  X.Wu, P.M.Flatt, O.Schlorke, A.Zeeck, T.Dairi, T.Mahmud
- Journal Title
  
  ChemBioChem. 8
  
  Pages: 239-248
- Data Source
  KAKENHI-PROJECT-18018035
[Journal Article] Cloning of the GeneCluster Responsible for Biosynthesisof KS-505a (longestin), a UniqueTetraterpenoid2007
- Author(s)
  Y. Hayashi, H. Onaka, N. Itoh, H. Seto,and T. Dairi
- Journal Title
  
  Biosci. Biotech.Biochem 71
  
  Pages: 3072-3081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510220
[Journal Article] A Comparative Analysis of the Sugar Phosphate Cyclase Superfamily Involved in Primary and Secondary Metabolism.2007
- Author(s)
  X.Wu, P.M.Flatt, O.Schlorke, A.Zeeck, T.Dairi, T.Mahmud
- Journal Title
  
  ChemBioChem. 8
  
  Pages: 239-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi2007
- Author(s)
  T.Toyomasu, M.Tsukahara, A.Kaneko, R.Niida, W.Mitsuhashi, T.Dairi, N.Kato, T.Sassa
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 104
  
  Pages: 3084-3088
- Data Source
  KAKENHI-PROJECT-18018035
[Journal Article] 放線菌の多様なイソプレノイド生合成遺伝子2006
- Author(s)
  大利徹
- Journal Title
  
  バイオサイエンスとインダストリー 64
  
  Pages: 433-438
- NAID
  10017643308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] 放線菌の多様なイソプレノイド生合成遺伝子2006
- Author(s)
  大利徹
- Journal Title
  
  バイオサイエンスとインダストリー 64
  
  Pages: 433-438
- NAID
  10017643308
- Data Source
  KAKENHI-PROJECT-18018035
[Journal Article] Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton.2005
- Author(s)
  C.Nakano, T.Okamura, T.Sato, T.Dairi, T.Hoshino
- Journal Title
  
  Chem Commun Apr 21 ; (8)
  
  Pages: 1016-1018
- NAID
  120006745822
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Studies on biosynthetic genes and enzymes of isoprenoids produced by ctinomycetes2005
- Author(s)
  T.Dairi
- Journal Title
  
  J.Antibiot. 58
  
  Pages: 227-243
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes2005
- Author(s)
  T.Dairi
- Journal Title
  
  Japanese J.Antibiot. 58
  
  Pages: 87-98
- NAID
  10014493589
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Heterologous mevalonate production in Streptomyces lividans TK232004
- Author(s)
  T.Kuzuyama, T.Dairi, H.Yamashita, Y.Shoji, H.Seto.
- Journal Title
  
  Biosci.Biotech.Biochem. 68
  
  Pages: 931-934
- NAID
  10013144128
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Identification and cloning of the gene involved in the final step of chlortetracycline biosynthesis in Streptomyces aureofaciens.2004
- Author(s)
  T.Nakano, K.Miyake, H.Endo, T.Dairi, T.Mizukami, R.Katsumata
- Journal Title
  
  Biosci.Biotech.Biochem. 68
  
  Pages: 1345-1352
- NAID
  10013286847
- Data Source
  KAKENHI-PROJECT-16310153
[Journal Article] Presence of copalyl diphosphate synthase gene in an actinomycete possessing the mevalonate pathway2004
- Author(s)
  T.Kawasaki, T.Kuzuyama, Y.Kuwamori, N.Matsuura, N.Itoh, K.Furihata, H.Seto, T.Dairi
- Journal Title
  
  J.Antibiot. 57
  
  Pages: 739-747
- NAID
  10014024066
- Data Source
  KAKENHI-PROJECT-16310153
[Patent] 特許2007
- Inventor(s)
  瀬戸治男、大利徹
- Industrial Property Rights Holder
  株式会社ADEKA
- Industrial Property Number
  2007-147510
- Filing Date
  2007-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380075
[Patent] 特許2007
- Inventor(s)
  瀬戸治男、大利徹
- Industrial Property Rights Holder
  株式会社ADEKA
- Patent Publication Number
  2008-011854
- Filing Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-17380075
[Presentation] INVOLVEMENT OF PEPTIDE EPIMERIZATION IN THE BIOSYTHESIS OF THE LINARIDIN CLASS RIBOSOMALLY SYNTHESIZED AND POST-TRANSLATIONALLY MODIFIED PEPTIDES2023
- Author(s)
  Wanlu Xiao, Yasushi Ogasawara, Yasuharu Satoh and Tohru Dairi
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 微細藻類由来DHA合成酵素のketosynthaseドメインの機能解析2023
- Author(s)
  尾形海斗、小林飛悠、佐藤康治、丸山千登勢、濱野吉十、小笠原泰志、大利徹
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 新規ペプチドエピメラーゼMslHの反応機構の解析2023
- Author(s)
  川上篤士、中嶋優、森田洋行、小笠原泰志、大利徹
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] X-ray crystallographic analysis of lasso peptide epimerase; MslH2023
- Author(s)
  Yu Nakashima, Atsushi Kawakami, Yasushi Ogasawara, Tohru Dairi, and Hiroyuki Morita
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 抗生物質resormycinが有するβ-homolysineの生合成機構の解明2023
- Author(s)
  今堀千咲、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Catalytic mechanism of MslH epimerizing C-terminal L-Trp of ribosomal lasso peptide, MS-2712023
- Author(s)
  Atsushi Kawakami, Yu Nakashima, Hiroyuki Morita, Yasushi Ogasawara, Tohru Dairi
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ペプチド異性化酵素Murlの構造機能解析を指向したリガンド分子の合成研究2023
- Author(s)
  山岡拓海、石川文洋、小笠原泰志、大利徹、田邊元三
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 新規ペプチドエピメラーゼMurLの反応機構解析2023
- Author(s)
  堀内柾希、中尾優文、中嶋優、森田洋行、小笠原泰志、大利徹
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Cyclopropane Formation in the Biosyntheses of Hormaomycins and Belactosins: Sequential Nitration and Cyclopropanation by Metalloenzymes2023
- Author(s)
  Yasushi Ogasawara, Ryo Shimaya, Wei-chen Chang, Tohru Dairi
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Phenylalanine hydroxylase found in the resormycin biosynthetic enzymes2023
- Author(s)
  Chihiro Kishi, Yasushi Ogasawara, Kazuya Yamanaka, Tohru Dairi, Yoshimitsu Hamano, Chitose Maruyama
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Resormycin生合成酵素群より見出したphenylalanine水酸化酵素の機能解析2023
- Author(s)
  岸千紘、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2023年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Biosynthetic Study of Antitumor Antibiotic Mitomycins2023
- Author(s)
  Yudai Takahashi, Kenichi Yokoyama, Tohru Dairi and Yasushi Ogasawara
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 微生物天然化合物の構造・機能多様性を創出する新規生合成酵素・機構に関する研究2023
- Author(s)
  大利　徹
- Organizer
  2023年度日本農芸化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 鉄/α-ケトグルタル酸依存シクロプロパン環化酵素オルソログの機能解析2022
- Author(s)
  島谷諒, 大利徹, 小笠原泰志
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 三員環構造を有するペプチド抗生物質ベラクトシンとホルマオマイシンの生合成研究2022
- Author(s)
  島谷　諒、大利徹、小笠原泰志
- Organizer
  2022年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 微細藻類由来DHA合成酵素のdehydrataseドメインの機能解析2022
- Author(s)
  小林飛悠、佐藤康治、小笠原泰志、大利徹
- Organizer
  令和4年度　日本農芸化学会北海道・東北支部合同支部会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ラッソペプチドRES-701の生合成研究2022
- Author(s)
  山谷　優花、小笠原泰志、大利徹
- Organizer
  2022年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Conversion of DHA synthase to EPA synthase based on the control mechanism of carbon chain length2022
- Author(s)
  Tohru Dairi
- Organizer
  Active Enzyme Molecule 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Involvement of Peptide Epimerization in the biosynthesis of Linaridin Class Ribosomally Synthesized and Post-translationally Modified Peptides2022
- Author(s)
  Wanlu Xiao、小笠原泰志、大利徹
- Organizer
  2022年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 高機能性生体分子の創成をめざした生合成マシナリーの基盤解明～新規ペプチドエピメラーゼの発見と機能解析～2022
- Author(s)
  大利　徹
- Organizer
  科研費-新学術領域-生合成リデザイン取りまとめシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 新規ペプチドエピメラーゼMslHの反応機構解析2022
- Author(s)
  川上篤士、中嶋優、森田洋行、小笠原泰志、大利徹
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 微細藻類由来DHA合成酵素の炭素鎖伸長反応の解析2022
- Author(s)
  仲間　陸、佐藤康治、小笠原泰志、大利徹
- Organizer
  2022年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2022
- Author(s)
  高橋佑大、中川　陽、大利　徹、小笠原泰志
- Organizer
  令和4年　日本農芸化学会北海道支部学術講演会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Two novel types of peptide epimerases to introduce D-amino acid residues in the biosynthesis of ribosomally synthesized and post-translationally modified peptides2022
- Author(s)
  小笠原泰志、大利徹
- Organizer
  Sapporo Summer Seminar on Natural Product Biosynthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Resormycin 生合成遺伝子群に見出した Phenylalanine 修飾酵素の機能解析2022
- Author(s)
  岸千紘、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ポリグルタミン酸生合成に関与する新規エピメリ化酵素の解析2022
- Author(s)
  作田萌香、小笠原泰志、大利徹
- Organizer
  令和4年度　日本農芸化学会北海道・東北支部合同支部会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 有用化合物の微生物発酵生産～EPAと抗酸化剤エルゴチオネイン～2022
- Author(s)
  大利　徹
- Organizer
  ファーマラボ EXPO 大阪アカデミックフォーラム
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ラッソペプチド生合成を担うエピメリ化酵素 MslH のX 線結晶構造解析2022
- Author(s)
  中嶋優、川上篤士、小笠原泰志、大利徹、森田洋行
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 新規ペプチドエピメラーゼMslHの反応機構解析2022
- Author(s)
  川上篤士、中嶋　優、森田洋行、小笠原　泰志、大利　徹
- Organizer
  令和4年　日本農芸化学会北海道支部学術講演会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ペプチドグリカン新規生合成経路の阻害剤探索2022
- Author(s)
  梅津秀平, 小笠原泰志, 大利徹
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] Involvement of peptide epimerization in the biosynthesis of the linaridin class ribosomally synthesized and post-translationally modified peptides2022
- Author(s)
  Wanlu Xiao, Yasushi Ogasawara, Yasuharu Satoh, and Tohru Dairi
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 抗生物質 resormycin が有するβ-homolysine の生合成機構の解明2022
- Author(s)
  今堀千咲、小笠原泰志、山中一也、五十嵐雅之、大利徹、濱野吉十、丸山千登勢
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] ペプチドを基質とする新規エピメラーゼの探索と解析2022
- Author(s)
  小笠原泰志、馮智、肖碗路、重松真由子、佐藤将太、加藤陽菜多、大利徹
- Organizer
  第64回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] イソキサゾリン構造を有するアシビシンの生合成解析2022
- Author(s)
  布田大志、小笠原　泰志、大利　徹
- Organizer
  令和4年　日本農芸化学会北海道支部学術講演会
- Data Source
  KAKENHI-PROJECT-22H04976
[Presentation] 病原微生物が持つ特異代謝経路をターゲットとした高特異性抗生剤の探索2021
- Author(s)
  大利　徹
- Organizer
  ファーマラボ EXPO [東京] アカデミックフォーラム
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 微細藻類由来DHA合成酵素の炭素鎖長制御機構の解明2021
- Author(s)
  仲間陸、佐藤康治、小笠原泰志、大利徹
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 新規メナキノン生合成経路阻害剤の探索2021
- Author(s)
  梅津秀平、小笠原泰志、大利徹
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] New Enzymes catalyzing peptide epimerizations2021
- Author(s)
  Tohru Dairi
- Organizer
  PacifiChem 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ポリグルタミン酸生合成におけるエピメリ化酵素の同定2021
- Author(s)
  加藤陽菜多、小笠原泰志、大利徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 微細藻類由来DHA合成酵素のdehydrataseドメインの機能解析2021
- Author(s)
  小林飛悠、佐藤康治、小笠原泰志、大利徹
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] メナキノン新規生合成経路阻害剤の探索2021
- Author(s)
  梅津秀平、小笠原泰志、稲橋佑起、野中健一、大利徹
- Organizer
  第23回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Flavonoids from Woodfordia fruticosa as potential SmltD inhibitors in the alternative biosynthetic pathway of peptidoglycan2021
- Author(s)
  Yuan-E Lee, Takeshi Kodama, Nwet Nwet Win, Dae-Won Ki, Tohru Dairi, Hiroyuki Morita
- Organizer
  日本生薬学会年会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 三員環構造を有するペプチド抗生物質ベラクトシンとホルマオマイシンの生合成研究2021
- Author(s)
  島谷諒、大利徹、小笠原泰志
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 新規ATP依存ペプチドエピメラーゼMurLの反応機構解析2021
- Author(s)
  中尾優文、小笠原泰志、佐藤康治、大利　徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] メナキノン新規生合成経路阻害剤の探索2021
- Author(s)
  梅津秀平、小笠原泰志、稲橋佑起、野中健一、大利徹
- Organizer
  日本放線菌学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Identification and Characterization of the Novel Peptide Epimerase Responsible for the C-terminal D-Tryptophan Introduction in the Biosynthesis of Lasso Peptide, MS-2712021
- Author(s)
  Zhi Feng, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Identification and Characterization of the Novel Peptide Epimerase Responsible for the C-terminal D-Tryptophan Introduction in the Biosynthesis of Lasso Peptide, MS-2712021
- Author(s)
  Zhi Feng, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Analysis of a novel pathway for para-aminobenzoate biosynthesis in bacteria2021
- Author(s)
  Wanlu Xiao, Yasuharu Satoh, Yasushi Ogasawara, Tohru Dairi
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ポリグルタミン酸生合成におけるエピメリ化酵素の同定2021
- Author(s)
  加藤陽菜多、小笠原泰志、大利徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Linaridin natural products containing d-amino acids2021
- Author(s)
  Wanlu Xiao, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  日本農芸化学会北海道支部大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2021
- Author(s)
  中川　陽、小笠原泰志、大利　徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2021
- Author(s)
  中川　陽、小笠原泰志、大利　徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 新規ATP依存ペプチドエピメラーゼMurLの反応機構解析2021
- Author(s)
  中尾優文、小笠原泰志、佐藤康治、大利　徹
- Organizer
  2021年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] New Peptide Epimerase in the Biosynthesis of a D-Tryptophan Containing Lasso Peptide, MS-2712021
- Author(s)
  Yasushi Ogasawara and Tohru Dairi
- Organizer
  Directing Biosynthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 植物病原菌に見出した新規ペプチドグリカン生合成経路2020
- Author(s)
  小笠原　泰志、大利　徹
- Organizer
  第6回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 新規ATP依存ペプチドエピメラーゼMurLの反応機構解析2020
- Author(s)
  中尾優文、小笠原泰志、佐藤康治、大利徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] エルゴチオネインの組換え微生物による発酵生産2020
- Author(s)
  佐藤康治、田草川隼、小笠原泰志、大津厳生、大利徹
- Organizer
  第１回エルゴチオネイン・セレノネイン研究会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸合成酵素の生産物リリース機構の解明2020
- Author(s)
  林祥平、小笠原泰志、佐藤康治、丸山千登勢、濱野吉十、大利徹
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Identification and Characterization of the Peptide Epimerase Catalyzing Isomerization of the C-terminal L-Tryptophan Residue in the Biosynthesis of Lasso Peptide, MS-2712020
- Author(s)
  Zhi Feng, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] In vitro characterization of early steps in the biosynthesis of antitumor antibiotics mitomycins2020
- Author(s)
  Y. Ogasawara, Y. Nakagawa, C. Maruyama, Y. Hamano, and T. Dairi
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ポリグルタミン酸生合成におけるエピメリ化酵素の同定2020
- Author(s)
  加藤　陽菜多、小笠原　泰志、大利　徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] メナキノン新規生合成経路の最終段階の解明2020
- Author(s)
  青木風花、清水庸平、小笠原泰志、大利　徹
- Organizer
  第30回イソプレノイド研究会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ポリグルタミン酸生合成におけるエピメリ化酵素の同定2020
- Author(s)
  加藤　陽菜多、小笠原　泰志、大利　徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 新規ＡＴＰ依存ペプチドエピメラーゼMurLの反応機構解析2020
- Author(s)
  中尾優文、小笠原泰志、佐藤康治、大利徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Identification and Characterization of the Peptide Epimerase Catalyzing Isomerization of the C-terminal L-Tryptophan Residue in the Biosynthesis of Lasso Peptide, MS-2712020
- Author(s)
  Zhi Feng, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting polyunsaturated fatty acid synthases for product control2020
- Author(s)
  S. Hayashi, Y. Satoh, Y. Ogasawara, and T. Dairi
- Organizer
  3rd International Conference on Natural Product Discovery and Development in the Genomic Era
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Investigation of a novel epimerase in the biosynthesis of D-tryptophan containing lasso peptide, MS-2712020
- Author(s)
  Z. Feng, Y. Ogasawara, and T. Dairi
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2020
- Author(s)
  中川　陽、小笠原泰志、大利　徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2020
- Author(s)
  中川陽、小笠原　泰志、大利　徹
- Organizer
  2020年度日本農芸化学会北海道支部／日本栄養・食糧学会北海道支部　合同学術講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 新規ペプチドグリカン生合成経路阻害剤の探索2020
- Author(s)
  清水庸平、佐藤洋平、小笠原泰志、米田友貴、猪熊泰英、大利徹
- Organizer
  2020年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の精密解析2019
- Author(s)
  林祥平、佐藤康治、丸山千登勢、濱野吉十、小笠原泰志、大利徹
- Organizer
  第61回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 精密解析に基づく多価不飽和脂肪酸生合成酵素の論理的機能改変2019
- Author(s)
  大利徹
- Organizer
  科研費新学術領域研究「生合成リデザイン」第６回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸合成酵素の機能改変2019
- Author(s)
  大塚慎、池内健心、林祥平、中真以、小林洸太、小笠原泰志、佐藤康治、氏原哲朗、大利徹
- Organizer
  第３回　新学術領域研究「生合成リデザイン」若手シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] in vitro解析による多価不飽和脂肪酸生合成酵素の炭素鎖長制御機構の解明2019
- Author(s)
  林祥平、小笠原泰志、佐藤康治、丸山千登勢、濱野吉十、氏原哲朗、大利徹
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 抗腫瘍抗生物質マイトマイシンの初期生合成機構のin vitro解析2019
- Author(s)
  中川陽、小笠原泰志、丸山千登勢、濱野吉十、大利徹
- Organizer
  2019年度（第34回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 精密解析に基づく多価不飽和脂肪酸生合成酵素の機能改変2019
- Author(s)
  林祥平、佐藤康治、小笠原泰志、大利徹
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting polyunsaturated fatty acid synthases for product control2019
- Author(s)
  S. Hayashi, Y. Satoh, Y. Ogasawara, and T. Dairi
- Organizer
  Annual Meeting of the Society for Industrial Microbiology and Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Biosynthetic Gene Cluster of a D-Tryptophan-containing lasso peptide, MS-2712019
- Author(s)
  Z. Feng, Y. Ogasawara, S. Nomura, and T. Dairi
- Organizer
  International Symposium on Biopolymer Synthesis and degradation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Biosynthetic Gene Cluster of a D-Tryptophan Containing Lasso Peptide, MS-2712019
- Author(s)
  Zhi Feng, Yasushi Ogasawara, Satoshi Nomura and Tohru Dairi
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] 抗腫瘍抗生物質マイトマイシンの生合成解析2019
- Author(s)
  中川陽、小笠原泰志、大利徹
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Involvement of peptide epimerization in poly-glutamic acid biosynthesis2019
- Author(s)
  Y. Ogasawara, M. Shigematsu, S. Sato, H. Kato, and T. Dairi
- Organizer
  Annual Meeting of the Society for Industrial Microbiology and Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Unique enzymes involved in biosynthesis of natural products produced by actinomycetes2019
- Author(s)
  T. Dairi
- Organizer
  International Workshop on Biology and Applications of Actinomycetes
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Biosynthetic gene cluster of a D-tryptophan-containing lasso peptide, MS-2712019
- Author(s)
  Z. Feng, Y. Ogasawara, S. Nomura, and T. Dairi
- Organizer
  Cold Spring Harbor Asia meeting on Chemical Biology and Drug Discovery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ペプチドグリカン新規生合成経路阻害剤の探索2019
- Author(s)
  清水庸平、佐藤洋平、小笠原泰志、米田友貴、猪熊泰英、大利徹
- Organizer
  2019年度（第34回）日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Biosynthetic Gene Cluster of a D-Tryptophan Containing Lasso Peptide, MS-2712019
- Author(s)
  Zhi Feng, Yasushi Ogasawara, Satoshi Nomura and Tohru Dairi
- Organizer
  2nd China-Japan Joint Symposium on Natural Product Biosynthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] ペプチドグリカン新規生合成経路阻害剤の探索2019
- Author(s)
  清水庸平, 佐藤洋平, 小笠原泰志, 米田友貴, 猪熊泰英, 大利徹
- Organizer
  2019年度日本生物工学会北日本支部大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] in vivo解析による多価不飽和脂肪酸生合成酵素の生成物制御ドメインの同定2019
- Author(s)
  林祥平、中真以、佐藤康治、氏原哲朗、大利徹
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Engineering of polyunsaturated fatty acid synthase to alter the product specificity2019
- Author(s)
  M. Ohtsuka, K. Ikeuchi, S. Hayashi, M. Naka, K. Kobayashi, Y. Satoh, Y. Ogasawara, and T. Dairi
- Organizer
  International Symposium on Biopolymer Synthesis and Degradation
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ペプチドリガーゼ相同遺伝子の探索と機能解析2019
- Author(s)
  成冨駿、小笠原泰志、大利徹
- Organizer
  2019年度（第34回）日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting polyunsaturated fatty acid synthases for product profile control2019
- Author(s)
  Shohei Hayashi, Yasuharu Satoh, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  2nd China-Japan Joint Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] A Glycopeptidyl-Glutamate Epimerase for Bacterial Peptidoglycan Biosynthesis2019
- Author(s)
  Ruoyin Feng, Yasuharu Satoh, Yasushi Ogasawara, Hiroyuki Morita, Tohru Yoshimura, and Tohru Dairi
- Organizer
  2nd China-Japan Joint Symposium on Natural Product Biosynthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の論理的機能改変2019
- Author(s)
  池内健心、中真以、林祥平、大塚慎、小林洸太、佐藤康治、小笠原泰志、氏原哲朗、大利徹
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 精密解析に基づく多価不飽和脂肪酸生合成酵素の機能改変2019
- Author(s)
  林祥平、佐藤康治、小笠原泰志、大利徹
- Organizer
  第71回日本生物工学会大会シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ポリグルタミン酸生合成における新規エピメリ化反応2019
- Author(s)
  佐藤将太、重松真由子、加藤陽菜多、小笠原泰志、大利徹
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] Exploration of futalosine pathway specific inhibitors2019
- Author(s)
  Y. Shimizu, K. Kondo, Y. Sato, Y. Ogasawara, and T. Dairi
- Organizer
  International Symposium on Biopolymer Synthesis and Degradation
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ペプチドリガーゼ相同遺伝子の探索と機能解析2019
- Author(s)
  成冨駿，小笠原泰志，大利徹
- Organizer
  2019年度日本生物工学会北日本支部大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ポリグルタミン酸生合成における新規エピメリ化反応2019
- Author(s)
  加藤陽菜多、重松真由子、佐藤将太、小笠原泰志、大利徹
- Organizer
  第３回　新学術領域研究「生合成リデザイン」若手シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] メナキノン新規生合成経路阻害剤の探索2019
- Author(s)
  青木風花、小笠原泰志、松本厚子、大利徹
- Organizer
  2019年度（第34回）日本放線菌学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting polyunsaturated fatty acid synthases for product control2019
- Author(s)
  T. Dairi
- Organizer
  Enzyme Engineering XXV
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] in vitro解析による多価不飽和脂肪酸生合成酵素のcis二重結合形成機構の解明2019
- Author(s)
  林祥平、小笠原泰志、佐藤康治、丸山千登勢、濱野吉十、氏原哲朗、大利徹
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Recognition mechanism of substrate chirality in UDP-MurNAc-L-Ala-Glu synthetase2019
- Author(s)
  Ruoyin FENG、Yasuharu SATOH、Hiroyuki MORITA、Yasushi OGASAWARA、and Tohru DAIRI
- Organizer
  2019年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] メナキノン新規生合成経路阻害剤の探索2018
- Author(s)
  清水庸平、小笠原泰志、松本厚子、大利　徹
- Organizer
  2018年度農芸化学会北海道支部・東北支部合同支部大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸合成酵素における3-ケトアシルリダクターゼとデヒドラターゼの機能解析2018
- Author(s)
  林祥平、佐藤康治、小笠原泰志、氏原哲朗、大利徹
- Organizer
  2018年度日本農芸化学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for bacterial peptidoglycan biosynthesis2018
- Author(s)
  Tohru Dairi
- Organizer
  The 3rd foresight symposium on Chemical & Synthetic Biology of Natural Products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis2018
- Author(s)
  Ruoyin Feng, Yasuharu Satoh, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  3rd European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の機能改変2018
- Author(s)
  池内健心、林　祥平、大塚　慎、小林洸太、佐藤康治、大利　徹
- Organizer
  2018年度日本生物工学会北日本支部札幌シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Aspergillus oryzaeを用いたergothioneine生産2018
- Author(s)
  田草川隼、佐藤康治、大津厳生、大利　徹
- Organizer
  2018年度農芸化学会北海道支部第二回講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の不飽和度制御機構の解明2018
- Author(s)
  林　祥平、佐藤康治、小笠原泰志、大利　徹
- Organizer
  2018年度日本生物工学会北日本支部札幌シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Alternative biosynthetic pathways for primary metabolites in microorganisms are targets for specific antibiotics?2018
- Author(s)
  T. Dairi
- Organizer
  Natural Product Discovery and Development in the Genomic Era
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ペプチドグリカンの新しい生成機構2018
- Author(s)
  大利　徹
- Organizer
  2018年度日本農芸化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の機能改変2018
- Author(s)
  池内健心、林　祥平、大塚　慎、小林洸太、佐藤康治、大利　徹
- Organizer
  2018年度農芸化学会北海道支部・東北支部合同支部大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for bacterial peptidoglycan biosynthesis2018
- Author(s)
  Ruoyin Feng, Yasuharu Satoh, Yasushi Ogasawara, Tohru Yoshimura, and Tohru Dairi
- Organizer
  15th Japan-China-Korea Joint Symposium on Enzyme Engineering
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Biosynthetic Gene Cluster of a-D-Tryptophan Containing Lasso Peptide, MS-2712018
- Author(s)
  Zhi Feng, Yasushi Ogasawara, Satoshi Nomura and Tohru Dairi
- Organizer
  2018年度（第33回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-18H03937
[Presentation] カルボニルメチレン構造を有するシュードトリペプチド（Ketomemicin）の生合成機構2018
- Author(s)
  大利　徹
- Organizer
  2018年度日本農芸化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 高機能性生体分子の創成をめざした生合成マシナリーの基盤解明2018
- Author(s)
  大利徹
- Organizer
  科研費新学術「生合成リデザイン」、第4回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Functional analysis of 3-ketoacyl reductase and dehydratase domains in polyunsaturated fatty acid synthases2018
- Author(s)
  S. Hayashi, Y. Satoh, Y. Ogasawara, T. Ujihara, and T. Dairi
- Organizer
  International Symposium on Biomass Refinery: from Biomass Crops to Chemicals and Fuels
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] メナキノン新規生合成経路阻害剤の探索2018
- Author(s)
  清水庸平、小笠原泰志、大利　徹
- Organizer
  2018年度農芸化学会北海道支部第二回講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis2018
- Author(s)
  R Feng, Y. Satoh, Y. Ogasawara, T. Yoshimura, and T. Dairi
- Organizer
  International Symposium on Biomass Refinery: from Biomass Crops to Chemicals and Fuels
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting the biosynthetic machinery in bacterial polyunsaturated fatty acid synthases2018
- Author(s)
  Shohei Hayashi, Mai Naka, Yasuharu Satoh, Yasushi Ogasawara, and Tohru Dairi
- Organizer
  3rd European Conference on Natural Products
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Heterologous and high production of ergothioneine in E. coli2018
- Author(s)
  T. Dairi
- Organizer
  International Symposium on Biomass Refinery: from Biomass Crops to Chemicals and Fuels
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting the biosynthetic machinery in bacterial polyunsaturated fatty acid synthases2018
- Author(s)
  Tohru Dairi
- Organizer
  NOVEL ENZYMES 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] メナキノン新規生合成経路阻害剤の探索2018
- Author(s)
  清水庸平、小笠原泰志、大利　徹
- Organizer
  2018年度日本生物工学会北日本支部札幌シンポジウム
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 微生物に見出したペプチドグリカン新規生合成酵素の解析2018
- Author(s)
  馮若茵、佐藤康治、小笠原泰志、森田洋行、吉村徹、大利徹
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸生合成酵素の不飽和度制御機構の解明2018
- Author(s)
  林　祥平、佐藤康治、小笠原泰志、大利　徹
- Organizer
  2018年度農芸化学会北海道支部・東北支部合同支部大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Dissecting prokaryotic polyunsaturated fatty acid synthases2018
- Author(s)
  Tohru Dairi
- Organizer
  9th International Congress on Biocatalysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸合成酵素の機能改変2018
- Author(s)
  池内健心、林祥平、大塚慎、小林洸太、佐藤康治、小笠原泰志、大利徹
- Organizer
  2018年度農芸化学会北海道支部第二回講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for peptide biosynthesis in microorganisms2017
- Author(s)
  T. Dairi
- Organizer
  9th US-Japan Seminar on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for peptide biosynthesis in microorganisms2017
- Author(s)
  T. Dairi
- Organizer
  Italy-Japan Joint Symposium New Trends in Enzyme and Microbial Science in the Translational Biology Era
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 微生物に見出した多様なペプチド合成酵素2017
- Author(s)
  大利　徹
- Organizer
  第10回北陸合同バイオシンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 細菌のペプチドグリカン生合成に関与する新規酵素2017
- Author(s)
  Feng R.，佐藤康治，小笠原泰志，大利　徹
- Organizer
  平成29年度　日本農芸化学会北海道支部第１回講演会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 放線菌に見出されたペプチドリガーゼオルソログの機能解析2017
- Author(s)
  藤村祐子、小笠原泰志、大利徹
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学（京都府・京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ケトメミシンの生合成に関わるアミジノ基転移酵素の機能解析2017
- Author(s)
  小笠原泰志、藤盛道子、川田純平、大利徹
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学（京都府・京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis2017
- Author(s)
  馮若茵、佐藤康治、大利　徹
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学（京都府・京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Biosynthesis of the Carbonylmethylene Containing Pseudopeptides, Ketomemicins2017
- Author(s)
  Y. Ogasawara, J. Kawata, T. Naoe, M. Fujimori, and T. Dairi
- Organizer
  US-Japan Seminar on the Biosynthesis of Natural Products for Young Researchers
- Place of Presentation
  東京工業大学（東京都・目黒区）
- Year and Date
  2017-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis2017
- Author(s)
  R. Feng, Y. Satoh, Y. Ogasawara, T. Yoshimura, T. Dairi
- Organizer
  第32回（2017年度）日本放線菌学会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 高機能性生体分子の創成をめざした生合成マシナリーの基盤解明2017
- Author(s)
  大利　徹
- Organizer
  科研費新学術「生合成リデザイン」、第2回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ケトメミシンにみられるカルボニルメチレン型シュードペプチドの生合成2017
- Author(s)
  直江大樹, 川田純平, 小笠原泰志, 大利徹
- Organizer
  生合成リデザイン第１回若手シンポジウム
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] ペプチド系天然化合物JBIR-78およびJBIR-95の生合成研究2017
- Author(s)
  竹田薫平、見目晃平、佐藤康治、小笠原泰志、新家一男、大利徹
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Exploring Novel Peptide Ligase Orthologs-Discovery and Biosynthetic Studies of Carbonylmethylene-Containing Pseudotripeptides Ketomemicins-2017
- Author(s)
  Y. Ogasawara, J. Kawata, T. Naoe, M. Fujimori, M. Noike and T. Dairi
- Organizer
  Directing Biosynthesis V
- Place of Presentation
  Warwick　Univ (United Kingdom）
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] An unprecedented glutamate epimerase for bacterial peptidoglycan biosynthesis2017
- Author(s)
  R. Feng, Y. Satoh, Y. Ogasawara, and T. Dairi
- Organizer
  US-Japan Seminar on the Biosynthesis of Natural Products for Young Researchers
- Place of Presentation
  東京工業大学（東京都・目黒区）
- Year and Date
  2017-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Functional analysis of tandem acyl carrier protein in polyunsaturated fatty acid synthases2017
- Author(s)
  S. Hayashi, Y. Satoh and T. Dairi
- Organizer
  Directing Biosynthesis V
- Place of Presentation
  Warwick　Univ. (United Kingdom）
- Year and Date
  2017-03-20
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for peptide biosynthesis in microorganisms2017
- Author(s)
  T. Dairi
- Organizer
  China/Japan Symposium on Natural Product Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Functional analysis of tandem acyl carrier protein in polyunsaturated fatty acid synthases2017
- Author(s)
  S. Hayashi, Y. Satoh and T. Dairi
- Organizer
  US-Japan Seminar on the Biosynthesis of Natural Products for Young Researchers
- Place of Presentation
  東京工業大学（東京都・目黒区）
- Year and Date
  2017-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 多価不飽和脂肪酸合成酵素における3-ケトアシルリダクターゼとデヒドラターゼの機能解析2017
- Author(s)
  林祥平、佐藤康治、小笠原泰志, 氏原哲朗、大利徹
- Organizer
  第69回日本生物工学会大会
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] Exploring peptide ligase orthologs in actinobacteria2016
- Author(s)
  Y. Ogasawara, J. Kawata, M. Noike, Y. Satoh, K. Furihata, and T. Dairi
- Organizer
  The Fifth International Conference on Cofactors (ICC-05) and Active Enzyme Molecule 2016 (AEM 2016)
- Place of Presentation
  宇奈月国際会館（富山県・黒部市）
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 微生物に見出されたペプチドリガーゼオルソログノ機能解析2016
- Author(s)
  小笠原泰志、河田純平、佐藤康治、降旗一夫、大利徹
- Organizer
  2016年度日本農芸化学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 多価不飽和脂肪酸合成酵素の機能解析2016
- Author(s)
  林祥平、佐藤康治、氏原哲朗、大利徹
- Organizer
  日本生物工学会2016年度大会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] New enzymes for biosynthesis of ketomemicin, a pseudotripeptide with carbonylmethylene structure2016
- Author(s)
  Y. Ogasawara, J. Kawata, and T. Dairi
- Organizer
  5th International Conference on Novel Enzymes
- Place of Presentation
  Hampshire Hotel- Plaza Groningen (Netherlands)
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 多価不飽和脂肪酸合成酵素におけるタンデムアシルキャリアプロテインの機能解明2016
- Author(s)
  林祥平、佐藤康治、氏原哲朗、大利徹
- Organizer
  日本生物工学会2016年度大会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] カルボニルメチレン構造を持つシュードトリペプチド（ケトメミシン）の発見と酵素的全合成2016
- Author(s)
  小笠原泰志、川田純平、野池基義、藤盛道子、佐藤康治、降旗一夫、大利徹
- Organizer
  第58回天然有機化合物討論会
- Place of Presentation
  東北大学（宮城県・仙台市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] Photobacterium profundum 由来エイコサペンタエン酸合成酵素の異種宿主発現2016
- Author(s)
  中真以、林祥平、佐藤康治、氏原哲朗、大利徹
- Organizer
  日本生物工学会2016年度大会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] 放線菌に見出された新規ペプチドライゲースオルソログの機能解析2016
- Author(s)
  藤村祐子，小笠原泰志，大利徹
- Organizer
  2016年度日本農芸化学会北海道支部大会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2016-11-23
- Data Source
  KAKENHI-PLANNED-16H06452
[Presentation] ケトメミシンにみられるシュードペプチド部の生合成解析2016
- Author(s)
  川田純平、直江大樹、小笠原泰志、大利徹
- Organizer
  2016年度、日本放線菌学会大会
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] フェガノマイシン、レゾルシノマイシン類抗生物質の構造活性相関2016
- Author(s)
  小笠原泰志、藤盛道子、雄谷洸一、野池基義、大利徹
- Organizer
  2016年度日本農芸化学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] Peptide synthesis cooperatively achieved by peptide ligase and ribosomes2015
- Author(s)
  Tohru Dairi
- Organizer
  Pacifichem 2015
- Place of Presentation
  Sheraton Waikiki, Honolulu　（USA)
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] A novel enzyme capping N-terminus of various peptides with amidino-PheGly derivatives2015
- Author(s)
  Tohru Dairi
- Organizer
  42nd International Symposium & Annual Meeting (The Korean Society for Microbiology and Biotechnology)
- Place of Presentation
  Hwabaek International Convention Center, Gyeongju, Korea
- Year and Date
  2015-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 放線菌の新規ペプチドリガーゼ2015
- Author(s)
  大利　徹
- Organizer
  第88回日本生化学会大会シンポジウム
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 放線菌に見出したATP-grasp-ligaseが触媒する多様なアミド形成反応2015
- Author(s)
  大利　徹
- Organizer
  第67回日本生物工学会大会シンポジウム
- Place of Presentation
  城山観光ホテル（鹿児島県・鹿児島市)
- Year and Date
  2015-10-26
- Invited
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 放線菌に見いだされた新規ペプチドライゲースオルソログの機能解析2015
- Author(s)
  重松真由子，小笠原泰志，大利徹
- Organizer
  2015年度日本農芸化学会北海道支部大会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] Exploring Novel Peptide Ligase Orthologs in Actinobacteria2015
- Author(s)
  Y. Ogasawara, J. Kawata, M. Noike, K. Furihata and T. Dairi
- Organizer
  2nd European Conference on Natural Products
- Place of Presentation
  Goethe-Universität, Frankfurt/Main (Germany)
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] A novel enzyme capping N-terminus of various peptides with amidino-PheGly derivatives2015
- Author(s)
  Tohru Dairi
- Organizer
  2nd European Conference on Natural Products
- Place of Presentation
  Goethe-Universität, Frankfurt/Main (Germany)
- Year and Date
  2015-09-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03110
[Presentation] 放線菌に見いだされた新規ペプチドライゲースは幅広い基質特異性を持つ2014
- Author(s)
  野池基義,　松井崇,　佐藤康治,　森田洋行,　大利　徹
- Organizer
  日本農芸化学会北海道支部例会
- Place of Presentation
  北海道大学農学部（北海道札幌市）
- Year and Date
  2014-09-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Novel folate biosynthesis pathway2014
- Author(s)
  SATOH, Y., DAIRI, T.
- Organizer
  US-Japan seminar on the biosynthesis of natural products for young researcher
- Place of Presentation
  Tokyo Institute of Technology
- Year and Date
  2014-03-02
- Data Source
  KAKENHI-PROJECT-24710239
[Presentation] 放線菌に見いだされた新規ペプチドライゲースオーソログの機能解析2014
- Author(s)
  川田純平,　小笠原泰志,　野池基義,　大利　徹
- Organizer
  日本農芸化学会北海道支部例会
- Place of Presentation
  北海道大学農学部（北海道札幌市）
- Year and Date
  2014-09-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 麹菌異種発現系を利用した、インドールジテルペン類の迅速な酵素合成2014
- Author(s)
  田上紘一、南篤志、松本知之、五味勝也、大利徹、及川英秋
- Organizer
  日本農芸化学会大会
- Place of Presentation
  明治大学（神奈川県川崎市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] インドールジテルペンの生合成に関与するプレニル基転移酵素に関する研究－22014
- Author(s)
  劉成偉、藤盛道子、南篤志、野池基義、佐藤康治、大栗博毅、及川英秋、大利徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  明治大学（神奈川県川崎市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Novel folate biosynthetic pathway2014
- Author(s)
  Yasuharu SATOH, Tohru DAIRI
- Organizer
  US-Japan Seminar on the Biosynthesis of Natural Products for Young Researchers
- Place of Presentation
  Tokyo Institute of Technology（東京都）
- Data Source
  KAKENHI-PROJECT-24710239
[Presentation] インドールジテルペンの生合成に関与するプレニル基転移酵素に関する研究－12014
- Author(s)
  劉成偉、南篤志、野池基義、戸嶋浩明、及川英秋、大利徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  明治大学（神奈川県川崎市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] ペプチドライゲースとリボソームとの協同によるペプチド新奇生合成機構の解明2014
- Author(s)
  野池基義、雄谷洸一、佐々木郁雄、丸山千登勢、石川淳、佐藤康治、濱野吉十、伊藤肇、大利徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  明治大学（神奈川県川崎市）
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] インドールジテルペンの生合成に関与するプレニル基転移酵素に関する研究2014
- Author(s)
  劉成偉、藤盛道子、南篤志、野池基義、佐藤康治、大栗博毅、及川英秋、大利徹
- Organizer
  第24回イソプレノイド研究会例会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] インドールジテルペン生合成に関与するプレニル転移酵素は幅広い基質特異性と柔軟なregular/reverse選択性を併せ持つ2013
- Author(s)
  劉　成偉、南　篤志、野池基義、田上紘一、及川英秋、大利　徹
- Organizer
  第55回天然有機化合物討論会
- Place of Presentation
  同志社大学寒梅館（京都市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] ペプチド化合物の新規生合成マシナリー2013
- Author(s)
  大利　徹
- Organizer
  2013年度　日本農芸化学会大会
- Place of Presentation
  東北大学（宮城）
- Year and Date
  2013-03-24
- Invited
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Functional analysis of prenyltransferses responsible for diterpene biosynthesis in fungi.2013
- Author(s)
  C. W. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi.
- Organizer
  1st European Conference on Natural Products.
- Place of Presentation
  DECHEMA-Haus, Frankfurt, Germany
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] バクテリアにおける新規葉酸生合成経路の解明2013
- Author(s)
  佐藤康治, 小林大毅, 大利徹
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-24710239
[Presentation] 新規メナキノン生合成経路酵素MqnDの生成物・類似体複合体のX線結晶構造解析2013
- Author(s)
  松尾京子、石北央、大利徹、瀬戸治男、新井亮一
- Organizer
  平成25年度日本農芸化学会大会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] バクテリアにおける新規葉酸生合成経路の解明2013
- Author(s)
  佐藤康治，小林大毅，大利徹
- Organizer
  日本農芸化学2013年度大会
- Place of Presentation
  東北大学　宮城県仙台市
- Data Source
  KAKENHI-PROJECT-24710239
[Presentation] 糸状菌Phomopsis amygdaliが持インドールジテルペン生合成遺伝子クラスターの解析2013
- Author(s)
  劉　成偉、野池基義、田上紘一、南　篤志、及川英秋、大利　徹
- Organizer
  2013年度　日本農芸化学会大会
- Place of Presentation
  東北大学（宮城）
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Functional Analysis of Prenyltransferses Responsible for Diterpene Biosynthesis in Fungi2013
- Author(s)
  C. W. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi,
- Organizer
  11th TERPNET meeting
- Place of Presentation
  Kolymvari, Crete, Greece
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] Functional Analysis of Prenyltransferses Responsible for Diterpene Biosynthesis in Fungi.2013
- Author(s)
  C. W. Liu, M. Noike, A. Minami, H. Oikawa, and T. Dairi.
- Organizer
  11th TERPNET meeting
- Place of Presentation
  Orthodox Academy of Crete, Kolymvari, Crete, Greece.
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] バクテリアにおける新規葉酸生合成経路の解明2013
- Author(s)
  佐藤康治、小林大毅、大利徹
- Organizer
  平成25年度日本農芸化学会大会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-24651235
[Presentation] 放線菌に見出した新規ペプチドライゲース2013
- Author(s)
  野池基義、雄谷洸一、佐々木郁雄、丸山千登勢、石川　淳、佐藤康治、濱野吉十、伊藤　肇、大利徹
- Organizer
  2013年度（第28回）日本放線菌学会大会
- Place of Presentation
  メルパルク広島（広島市）
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 麹菌発現系を利用した糸状菌二次代謝産物生合成遺伝子の解析と物質生産2013
- Author(s)
  南篤志、田上紘一、千葉諒太、藤居瑠彌、劉成偉、笛木周平、七條好宏、井坂哲也、戸嶋浩明、五味勝也、大利徹、及川英秋
- Organizer
  第55回天然有機化合物討論会
- Place of Presentation
  同志社大学寒梅館（京都市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 糸状菌Phomopsis amygdaliのゲノム解析によるフシコクシン生合成遺伝子クラスターの同定・機能解析と応用2012
- Author(s)
  野池基義、小野裕介、加藤修雄、大利徹
- Organizer
  第6回日本ゲノム微生物学会年会
- Place of Presentation
  立教大学(東京)
- Year and Date
  2012-03-10
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Molecular breeding of a fungus producing a precursor molecule suitable for semi-synthesis, based on the dissection of the biosynthetic machinery2012
- Author(s)
  T. Dairi
- Organizer
  Directing Biosynthesis III
- Place of Presentation
  University of Nottingham　(UK)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] An alternative menaquinone biosynthetic pathway: an attractive target for drug discovery to Helicobacter pylori2012
- Author(s)
  Tohru Dairi
- Organizer
  17th Malaysian Chemical Congress (17MCC)
- Place of Presentation
  Putra World Trade Centre, Kuala Lumpur, Malaysia.
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] Molecular breeding of a fungus producing a diterpene intermediate suitable for semi-synthesis based on the dissection of the biosynthetic machinery2012
- Author(s)
  M. Noike, Y. Ono, N. Kato, and T. Dairi
- Organizer
  Society of Industrial Microbiology Meeting
- Place of Presentation
  Hilton Washington （USA）
- Year and Date
  2012-08-12
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] バクテリアにおける新規葉酸生合成経路の解明2012
- Author(s)
  佐藤康治、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] Molecular Breeding of a Fungus Producing a Precursor Molecule Suitable for Semi-synthesis, Based on the Dissection of the Biosynthetic Machinery2012
- Author(s)
  T. Dairi
- Organizer
  The International Conference of Natural Products Biosynthesis
- Place of Presentation
  淡路夢舞台国際会議場（兵庫）
- Year and Date
  2012-06-17
- Invited
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 微生物に見出されたメナキノン新規生合成経路の全容解明と抗ピロリ菌薬開発への応用2012
- Author(s)
  大利徹
- Organizer
  公益財団法人発酵研究所第6回研究報告会
- Place of Presentation
  千里ライフサイエンスセンター大阪
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン生合成マシナリーの解明と応用2012
- Author(s)
  大利徹
- Organizer
  平成24年度日本薬学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 補酵素類の生合成に関与する新規酵素の解析と応用2012
- Author(s)
  大利　徹
- Organizer
  第13回酵素応用シンポジウム
- Place of Presentation
  名古屋メルパルク
- Invited
- Data Source
  KAKENHI-PROJECT-24651235
[Presentation] An alternative menaquinone biosynthetic pathway: an attractive target for drug discovery to Helicobacter pylori2012
- Author(s)
  Tohru Dairi
- Organizer
  17th Malaysian Chemical Congress
- Place of Presentation
  Putra World Trade Centre, Kuala Lumpur, Malaysia
- Invited
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 微生物に見出されたメナキノン新規生合成経路の全容解明と抗ピロリ菌剤の開発2012
- Author(s)
  大利徹
- Organizer
  公益財団法人野田産業科学研究所、平成24年度研究成果発表会
- Place of Presentation
  東京会館
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 補酵素類の生合成に関与する新規酵素の解析と応用2012
- Author(s)
  大利徹
- Organizer
  第13回酵素応用シンポジウム
- Place of Presentation
  名古屋メルパルク
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 糸状菌Phomopsis amygdaliが持つインドールジテルペン生合成遺伝子クラスターの解析2012
- Author(s)
  劉　成偉、野池基義、田上紘一、南　篤志、及川英秋、大利　徹
- Organizer
  第22回ドリコールイソプレノイド研究会
- Place of Presentation
  新潟大学駅南キャンパス（新潟）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン(FC)生合成マシナリーの機能解明-2-2012
- Author(s)
  野池基義、荒木祐治、劉成偉、小野裕介、濱野吉十、樋口雄介、豊増知伸、佐々武史、加藤修雄、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 放線菌が持つメナキノン新規生合成経路の解明と特異的阻害剤の探索2012
- Author(s)
  池田駿介、池田安由美、佐藤康治、野池基義、瀬戸治男、大利徹
- Organizer
  2012年度(第27回)日本放線菌学会大会
- Place of Presentation
  府中の森芸術劇場
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] フタロシン(FL)経路の解析2012
- Author(s)
  池田駿介、柏崎恭平、小野裕介、池田安由美、佐藤康治、矢島新、瀬戸治男、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 放線菌が持つメナキノン新規生合成経路の解明と特異的阻害剤の探索2012
- Author(s)
  池田駿介、池田安由美、佐藤康治、野池基義、瀬戸治男、大利　徹
- Organizer
  2012年度（第27回）日本放線菌学会大会
- Place of Presentation
  府中の森芸術劇場（東京都）
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン(FC)生合成マシナリーの機能解明-3-2012
- Author(s)
  野池基義、小野裕介、長野竜郎、濱野吉十、樋口雄介、豊増知伸、佐々武史、加藤修雄、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン生合成マシナリーの全容解明2012
- Author(s)
  野池基義、小野裕介、加藤修雄、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Dissection of the biosynthetic machinery of fusicoccin A, a diterpene produced by a fungus- Logical breeding for production of a compound suitable for semi-synthesis -2012
- Author(s)
  M. Noike, Y. Ono, N. Kato, and T. Dairi
- Organizer
  Malaysian Cambodian Chemical Conference
- Place of Presentation
  Angkor Century Resort Spa (Cambodia)
- Year and Date
  2012-10-19
- Invited
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン(FC)生合成マシナリーの機能解明-1-2012
- Author(s)
  野池基義、小野裕介、谷尾亮、豊増知伸、佐々武史、加藤修雄、大利徹
- Organizer
  平成24年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] カビが生産するジテルペン(フシコクシン)生合成マシナリーの全容解明2011
- Author(s)
  野池基義、小野裕介、荒木祐治、谷尾亮、濱野吉十、樋口雄介、豊増知伸、佐々武史、加藤修雄、大利徹
- Organizer
  第21回ドリコールおよびイソプレノイド研究会例会
- Place of Presentation
  島根大学(松江市)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Microorganisms evolved vitamin biosynthetic enzymes in response to various environments, an example in menaquinone biosynthesis2011
- Author(s)
  Tohru Dairi
- Organizer
  IUMS 2011
- Place of Presentation
  札幌国際会議場(札幌市)(招待講演)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] メナキノン(MK)新規生合成経路阻害剤の探索2011
- Author(s)
  田中友理、國定孝夫、櫛田伸明、山田恵子、池田駿介、伊藤伸哉、瀬戸治男、大利徹
- Organizer
  平成23年度日本農芸化学会大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] An alternative menaquinone biosynthetic pathway: an attractive target for drug discovery to Helicobacter pylori2011
- Author(s)
  Tohru Dairi
- Organizer
  The Third International Conference on Cofactors 03 (ICC-03)
- Place of Presentation
  The University of Turku, Finland
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン生合成マシナリーの全容解明2011
- Author(s)
  野池基義、小野裕介、荒木祐治、谷尾亮、濱野吉十、樋口雄介、豊増知伸、佐々武史、加藤修雄、大利徹
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪国際交流センター(大阪市)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Microorganisms evolved vitamin biosynthetic enzymes in response to various environments, an example in menaquinone biosynthesis2011
- Author(s)
  Tohru Dairi
- Organizer
  The IUMS2011, Sapporo
- Place of Presentation
  札幌国際会議場
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] An alternative menaquinone biosynthetic pathway : an attractive target for drug discovery to Helicobacter pylori2011
- Author(s)
  Tohru Dairi
- Organizer
  The Third International Conference on Cofactors 03 (ICC-03)
- Place of Presentation
  The University of Turku, (Finland)(招待講演)
- Year and Date
  2011-07-10
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 微生物が生産する環状テルペノイド生合成マシナリーの解明と再構築2011
- Author(s)
  大利徹
- Organizer
  科研費「生合成マシナリー」第2回公開シンポジウム
- Place of Presentation
  東京大学大学院薬学研究科(東京)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 微生物におけるビタミン生合成経路の多様性2011
- Author(s)
  大利徹
- Organizer
  生物資源学特別セミナー
- Place of Presentation
  福井県立大学
- Year and Date
  2011-05-23
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] An alternative menaquinone biosynthetic pathway : an attractive target for drug discovery to Helicobacter pylori2011
- Author(s)
  Tohru Dairi
- Organizer
  The Third International Conference on Cofactors 03 (ICC-03)
- Place of Presentation
  The Univ.of Turku, (Finland)(招待講演)
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] フタロシン(FL)経路の初発反応の多様性2011
- Author(s)
  荒川知里、倉都将宏、伊藤伸哉、瀬戸治男、大利徹
- Organizer
  平成23年度日本農芸化学会大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 糸状菌Phomopsis amygdaliが生産するフシコクシン生合成マシナリーの全容解明2011
- Author(s)
  大利徹
- Organizer
  科研費「生合成マシナリー」第3回公開シンポジウム
- Place of Presentation
  東京大学(東京)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Search for a new metabolic pathway by genome mining in Streptomyces coelicolor2011
- Author(s)
  Kentaro Yanashima, Tomomi Matsui, Shunsuke Ikeda, Tohru Dairi
- Organizer
  日本放線菌学会2011年度大会
- Place of Presentation
  札幌国際会議場(札幌市)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 放線菌が持つメナキノン新規生合成経路の解明2010
- Author(s)
  大利徹
- Organizer
  平成22年度日本放線菌学会大会
- Place of Presentation
  東京、タワーホール船堀
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] Studies on the early biosynthetic step of the futalosine (menaquinone) pathway2010
- Author(s)
  Tohru Dairi
- Organizer
  Pacifichem 2010,Honolulu
- Place of Presentation
  シェラトンワイキキ
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 微生物に見出されたメナキノン新規生合成の解明にいたるストーリィー2010
- Author(s)
  大利徹
- Organizer
  第45回天然物化学談話会
- Place of Presentation
  三谷温泉ホテル明山荘愛知県蒲郡市招待講演
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 放線菌におけるフタロシン経路の初発反応の多様性2010
- Author(s)
  荒川知里、倉都将宏、瀬戸治男、大利徹
- Organizer
  平成22年度日本放線菌学会大会
- Place of Presentation
  東京、タワーホール船堀
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] An alternative menaquinone biosynthetic pathway: an attractive target for drug discovery to pathogenic Helicobacter and Chlamydia strains.2010
- Author(s)
  Tohru Dairi
- Organizer
  12th Japanese-Swiss Meeting on Biotechnology and BioprocessDevelopment, Toyama
- Place of Presentation
  富山国際会議場
- Year and Date
  2010-10-11
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] ピロリ菌が持つ特異的ビタミン生合成経路の解明と抗ピロリ菌薬開発への挑戦2010
- Author(s)
  大利徹
- Organizer
  第3回北大工学系-道総研連携フォーラム
- Place of Presentation
  北大創成科学研究棟
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] 微生物に見出されたメナキノン新規生合成の解明にいたるストーリィー2010
- Author(s)
  大利徹
- Organizer
  第45回天然物化学談話会
- Place of Presentation
  愛知県蒲郡市、ホテル明山荘
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22310139
[Presentation] An Alternative Menaquinone Biosyntetic Pathway Operating in Microorganisms2009
- Author(s)
  T.Dairi
- Organizer
  第25回内藤コンファレンス
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20018023
[Presentation] Studies on a new biosynthetic pathway for menaquinone2008
- Author(s)
  M., Fukawa, Y., Jinnai, T., Hiratsuka, K., Furihata, S., Itoh, T., Dairi
- Organizer
  National Meeting of Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Place of Presentation
  Meijo University, Nagoya
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380075
[Presentation] イネにおける2 種のent-コパリル2 リン酸合成酵素2008
- Author(s)
  豊増知伸、廣瀬祐子、黒田昌治、林豊、大利徹、三橋渉、松岡信、山根久和、佐々武史
- Organizer
  日本農芸化学会大会
- Place of Presentation
  名城大学
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] 新規メナキノン生合成経路に関する研究2008
- Author(s)
  府川美和子、瀬戸治男、大利徹
- Organizer
  日本農芸化学会
- Place of Presentation
  名古屋市名城大学
- Year and Date
  2008-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380075
[Presentation] Brasilicardin A 生合成遺伝子群の取得2008
- Author(s)
  林豊、松浦信康、戸嶋浩明、伊藤伸哉、石川淳、三上襄、大利徹
- Organizer
  平成20 年度日本放線菌学会大会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] An alternative menaquinone biosynthetic pathway operating in microorganism2008
- Author(s)
  T. Dairi
- Organizer
  The 2008 RIKEN Conference on Chemica 1 Biology
- Place of Presentation
  成田
- Data Source
  KAKENHI-PROJECT-20018023
[Presentation] Brasilicardin A生合成遺伝子群の取得2008
- Author(s)
  林豊, 松浦信康, 戸嶋浩明, 伊藤伸哉, 石川淳, 三上襄, 大利徹
- Organizer
  平成20年度日本放線菌学会大会
- Place of Presentation
  山梨県
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] 多環性テトラテルペン骨格を有するKS-505a 生合成遺伝子群のクローニング2008
- Author(s)
  林豊、尾仲宏康、伊藤伸哉、瀬戸治男、大利徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  名城大学
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] A new bacterial menaquinone biosynthetic pathway2008
- Author(s)
  T. Hiratsukal, K. Furihata, J Ishikawa, H. Yamashita, N. Itoh, H. Seto, and T. Dairi
- Organizer
  7th US-Japan Seminar on the Biosynthesis of Natural Products
- Place of Presentation
  La Jolla, CA
- Data Source
  KAKENHI-PROJECT-20018023
[Presentation] 新規メナキノン生合成経路に関する研究2008
- Author(s)
  府川美和子、瀬戸治男、大利徹
- Organizer
  日本農芸化学会
- Place of Presentation
  名古屋名城大学
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-17380075
[Presentation] 微生物に見出されたメナキノン新規生合成経路の解明2008
- Author(s)
  平塚知成、降旗一夫、石川淳山下治之、伊藤伸哉、瀬戸治男大利徹
- Organizer
  平成20年度日本放線菌学会大会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-20018023
[Presentation] 放線菌に見出されたユニークな一次構造を持つジテルペン環化酵素群の解析2007
- Author(s)
  池田千穂、林豊、伊藤伸哉、瀬戸治男、大利徹
- Organizer
  第49 回天然有機化合物討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] Functional Analysisof Eubacterial ent-CopalylDiphosphate Synthase andPimara-9(11)2007
- Author(s)
  T. Dairi, C. Ikeda, Y. Hayashi, N.Itoh, and H. Seto
- Organizer
  15-diene Synthase withUnique Primary Sequences. 14thInternational Symposium on the Biologyof Actinomycetes
- Place of Presentation
  Newcastle, UK
- Year and Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] イネのフィトアレキシンとジベレリン生合成に関与するent-コパリル2リン酸合成酵素の酵素的性質の比較2007
- Author(s)
  廣瀬祐子、林豊、小野寺悠、三橋渉、佐々武史、大利徹、豊増知伸
- Organizer
  、第42 回植物化学調節学会
- Place of Presentation
  静岡
- Year and Date
  2007-10-29
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] 放線菌に見出された2つのジテルペン環化酵素、ent-copalyl diphosphate synthase(CDPS)とpimara-9(11),15-diene synthase(PDS)の酵素学的諸性質2007
- Author(s)
  大利徹等
- Organizer
  2007年度日本放線菌学会大会
- Place of Presentation
  尾道市
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] 放線菌に見出された2 つのジテルペン環化酵素、ent-copalyl diphosphatesynthase とpimara-9(11)2007
- Author(s)
  池田千穂、林豊、伊藤伸哉、大利徹
- Organizer
  15-dienesynthase の酵素学的諸性質、日本放線菌学会大会
- Place of Presentation
  尾道
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] ユニークな多環性テトラテルペン骨格を有するKS-505a(longestin)生合成遺伝子のクローニング2007
- Author(s)
  林豊、尾仲宏康、伊藤伸哉、瀬戸治夫、大利徹
- Organizer
  第17 回ドリコールおよびイソプレノイド研究会
- Place of Presentation
  京都大学
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19510220
[Presentation] 放線菌に見いだされた新規ペプチドライゲースは幅広い基質特異性を持つ
- Author(s)
  野池基義,　松井崇,　佐藤康治,　森田洋行,　大利　徹
- Organizer
  2014年度（第29回）日本放線菌学会大会
- Place of Presentation
  つくばカピオ（茨城県つくば市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 放線菌に見いだされた新規ペプチドライゲースオーソログの機能解析
- Author(s)
  川田純平,　小笠原泰志,　野池基義,　大利　徹
- Organizer
  2014年度（第29回）日本放線菌学会大会
- Place of Presentation
  つくばカピオ（茨城県つくば市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] ペプチドライゲースとリボソームによる協同的なペプチド新奇生合成機構の解明
- Author(s)
  大利　徹
- Organizer
  第34回　富山大学和漢医薬学総合研究所特別セミナー
- Place of Presentation
  富山国際会議場（富山市）
- Invited
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] リボソームと新規ペプチドライゲースによる協同的ペプチド生成機構
- Author(s)
  野池基義,　松井崇,　雄谷洸一,　佐々木郁雄,　丸山千登勢,　濱野吉十,　石川　淳,　佐藤康治,　伊藤　肇,　森田洋行,　大利　徹
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県立県民文化ホール（高知県高知市）
- Year and Date
  2014-10-15 – 2014-10-27
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 放線菌が持つペプチドリガーゼオーソログの機能解析-2-
- Author(s)
  小笠原泰志、川田純平、野池基義、降旗一夫、大利　徹
- Organizer
  2014年度　日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 放線菌が持つペプチドリガーゼオーソログの機能解析-1-
- Author(s)
  川田純平、小笠原泰志、野池基義、大利　徹
- Organizer
  2014年度　日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 放線菌が持つペプチドリガーゼオーソログの機能解析-2-
- Author(s)
  小笠原泰志、川田純平、野池基義、降旗一夫、大利　徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] リボソームと新規ペプチドリガーゼによる協調的ペプチド生成機構
- Author(s)
  大利　徹
- Organizer
  2014年度　日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 放線菌が持つペプチドリガーゼオーソログの機能解析-1-
- Author(s)
  川田純平、小笠原泰志、野池基義、大利　徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 放線菌に見いだされた新規ペプチドライゲースオーソログの機能解析
- Author(s)
  川田純平,　小笠原泰志,　野池基義,　大利　徹
- Organizer
  2014年度（第29回）日本放線菌学会大会
- Place of Presentation
  つくばカピオ（茨城県つくば市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] ペプチドライゲースとリボソームによる協同的なペプチド新奇生合成機構の解明
- Author(s)
  大利　徹
- Organizer
  生合成マシナリー：第６回公開シンポジウム
- Place of Presentation
  千葉大学、薬学部120周年記念講堂（千葉市）
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 緩い基質特異性を示すペプチドリガーゼの結晶構造からの考察と応用
- Author(s)
  野池基義、松井崇、小笠原泰志、森田洋行、大利　徹
- Organizer
  2014年度　日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 高度好熱菌由来メナキノン生合成酵素MqnD-基質・生成物複合体のX線結晶構造解析および酵素反応機構
- Author(s)
  新井亮一、池田早希、小松美沙紀、松尾京子、大利徹
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] リボソームと新規ペプチドリガーゼによる協調的ペプチド生成機構
- Author(s)
  大利　徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] インドールジテルペン・パキシリンの酵素的全合成
- Author(s)
  田上紘一、劉　成偉、南　篤志、野池基義、大利　徹、及川英秋
- Organizer
  平成25年度、万有札幌シンポジウム
- Place of Presentation
  北海道大学工学部（札幌市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] ペプチド系抗生物質フェガノマイシンの生合成に見いだされた新規ペプチドライゲースPGM1の結晶構造解析
- Author(s)
  松井崇、大瀧翔太、野池基義、大利　徹、森田洋行
- Organizer
  平成26年度日本結晶学会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 環状テルペノイドおよびヌクレオシド系抗生物質生合成マシナリーの解明と再構築
- Author(s)
  大利　徹
- Organizer
  生合成マシナリー：第５回公開シンポジウム
- Place of Presentation
  北海道大学工学部（札幌市）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] Crystal Structure of a Menaquinone Biosynthetic Enzyme, MqnD, Complexed with its Substrate and Product
- Author(s)
  Tohru Dairi
- Organizer
  15th IUBMB Conference
- Place of Presentation
  Academia Sinica, Taipei, Taiwan
- Year and Date
  2014-10-21 – 2014-10-26
- Invited
- Data Source
  KAKENHI-ORGANIZER-22108001
[Presentation] ペプチドライゲースとリボソームによる協同的なペプチド新奇生合成機構の解明
- Author(s)
  大利　徹
- Organizer
  公益社団法人日本農芸化学会中部支部第168回例会
- Place of Presentation
  名古屋大学シンポジオン（名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] 緩い基質特異性を示すペプチドリガーゼの結晶構造からの考察と応用
- Author(s)
  野池基義、松井崇、小笠原泰志、森田洋行、大利　徹
- Organizer
  日本農芸化学会大会
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-25 – 2015-03-29
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] リボソームと新規ペプチドライゲースによる協同的ペプチド生成機構
- Author(s)
  野池基義,　松井崇,　雄谷洸一,　佐々木郁雄,　丸山千登勢,　濱野吉十,　石川　淳,　佐藤康治,　伊藤　肇,　森田洋行,　大利　徹
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県立県民文化ホール（高知県高知市）
- Year and Date
  2014-10-15 – 2014-10-17
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] インドールジテルペン生合成に関与するプレニル転移酵素は幅広い基質特異性と柔軟なregular/reverse選択性を併せ持つ
- Author(s)
  劉　成偉、南　篤志、野池基義、田上紘一、及川英秋、大利　徹
- Organizer
  第２３回イソプレノイド研究会例会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 高度好熱菌由来メナキノン生合成酵素MqnD-基質(cDHFL)複合体のX 線結晶構造解析
- Author(s)
  新井亮一、池田早希、小松美沙紀、松尾京子、大利徹
- Organizer
  第8回バイオ関連化学シンポジウム
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] 放線菌に見いだされた新規ペプチドライゲースは幅広い基質特異性を持つ
- Author(s)
  野池基義,　松井崇,　佐藤康治,　森田洋行,　大利　徹
- Organizer
  2014年度（第29回）日本放線菌学会大会
- Place of Presentation
  つくばカピオ（茨城県つくば市）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25560397
[Presentation] Crystal Structure of a Menaquinone Biosynthetic Enzyme, MqnD, Complexed with its Substrate and Product
- Author(s)
  R. Arai, M. Komatsu, S. Ikeda, K. Matsuo, T. Dairi
- Organizer
  15th IUBMB Conference
- Place of Presentation
  台北（台湾）
- Year and Date
  2014-10-21 – 2014-10-26
- Data Source
  KAKENHI-PLANNED-23108101
[Presentation] ペプチド系抗生物質フェガノマイシンの生合成に見いだされた新規ペプチドライゲースPGM1の結晶構造解析
- Author(s)
  松井崇、大瀧翔太、野池基義、大利　徹、森田洋行
- Organizer
  平成26年度日本結晶学会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PLANNED-23108101

1. 濱野吉十 (50372834)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. EGUCHI Tadashi (60201365)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. ABE Ikuro (40305496)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. IKEDA Haruo (90159632)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. SATOH Yasuharu (30360928)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
6. OIKAWA Hideaki (00185175)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
7. KUZUYAMA Tomohisa (30280952)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. KATO Nobuo (50150537)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
9. MORITA HIROYUKI (20416663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
10. SAITO Kazuki (00146705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. GOMI Katsuya (60302197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KANAYA Shigehiko (90224584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. ISHIKAWA Jun (40202957)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. ASANO Yasuhisa (00222589)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KATO Yasuo (20254237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. MATSUURA Nobuyasu (60281250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. SASSA Takeshi (80023456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. HOSHINO Tsutomu (30165542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. OGASAWARA YASUSHI (20732986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 56 results
20. 菅裕明 (00361668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 梅野太輔 (00400812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. 南篤志 (40507191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
23. 渡辺賢二 (50360938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. 山崎真巳 (70222370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
25. 脇本敏幸 (70363900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
26. ARAI Ryouichi (50344023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. YAMADA Hideaki (30027180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KOMEDA Hidenobu (50285160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. UBUKATA Makoto (60168739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. TOYOMASU Tomonobu (60272085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. YAMANE Hisakazu (80090520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SETO Haruo (10013335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
33. SUE Masayuki (10328544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KURATSU Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. OBAYASHI Daiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
36. ヘイデンブロナ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. アーテミュイクピーター

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. ライスデイビット・W

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. ライスデイビッド・W

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. ウォーラーデイビッド・

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. ブリットン K・リンダ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. OHTSU Naoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. KODAMA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 大津厳生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
45. 河野祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

dairi tohru 大利 徹

DAIRI Tohru 大利 徹

Research Projects

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Co-Researchers

Dissecting biosynthetic machineries of natural peptides leading to structural and functional diversities.Principal Investigator

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Dissecting reaction mechanisms of novel peptide epimerasesPrincipal Investigator

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Studies on biosynthetic machinery of biologically active natural productsPrincipal Investigator

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Biosynthesis of the Carbonylmethylene Structure Found in a Class of Pseudotripeptides, KetomemicinsPrincipal Investigator

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Peptide synthesis cooperatively achieved by peptide ligase and ribosomesPrincipal Investigator

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Estimation of an alternative biosynthetic pathway for co-factors by close investigation of genome databases.Principal Investigator

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Studies on biosynthetic machineries for cyclic terpenoids and nucleoside antibioticsPrincipal Investigator

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微生物が生産する環状テルペノイド生合成マシナリーの解明と再構築Principal Investigator

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Screening of natural products which inhibits a new menaquinone biosynthetic pathwayPrincipal Investigator

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病原菌が持つメナキノン新規生合成経路の全容解明と経路特異的阻害剤の探索Principal Investigator

dairi tohru 大利徹

DAIRI Tohru 大利徹