Matsuzaka Takashi 松坂賢

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MATSUZAKA Takashi 松坂賢

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Researcher Number	70400679
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 筑波大学, 医学医療系, 教授 2011 – 2018: 筑波大学, 医学医療系, 准教授 2007 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 助教 2005 – 2006: 筑波大学, 大学院人間総合科学研究科, 助手 2005: 筑波大学, 大学院・人間総合科学研究科, 助手
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Applied health science / Applied health science Except Principal Investigator Metabolomics / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Applied health science / Basic Section 56030:Urology-related / Biological Sciences / Complex systems / Applied health science
Keywords	Principal Investigator 脂肪酸 / 脂肪酸伸長酵素 / 肝臓 / 糖尿病 / インスリン感受性 / ミトコンドリア / ベータ細胞 / 脂肪組織 / 生活習慣病 / Elovl6 … More / 脳 / エネルギー代謝 / 肥満 / 脂肪酸組成 / 骨格筋 / リピドミクス / 細胞外微小環境 / FGFR3 / 膵ベータ細胞 / 高血糖 / 膵臓 / セラミド / 膵β細胞 / カルジオリピン / 2型糖尿病 / NAFLD / 細胞増殖 / 脂肪毒性 / リノール酸 / オレイン酸 / 栄養学 / 脂質 / マクロファージ / 肝細胞 / インフラマソーム / 炎症 / 海馬 / アストロサイト / ニューロン / 嗜好性 / 脂肪酸合成 / メタボリックシンドローム / インスリン抵抗性 … More Except Principal Investigator 脂質代謝 / 生活習慣病 / 糖尿病 / 脂肪酸 / 転写因子 / 脂肪酸伸長酵素 / 動脈硬化 / 脂質 / CREBH / 転写調節 / 遺伝子発現 / インスリン抵抗性 / コレステロール / 非アルコール性脂肪肝 / 脂質異常症 / メタボリックシンドローム / エネルギー代謝 / TFE3 / 肥満 / SREBP / ELOVL5 / ELOVL2 / 腎癌 / 慢性炎症 / 脂肪毒性 / 脳 / 炎症 / ナノテクノロジー / 肝臓 / FGF21 / インスリン感受性 / 中性脂肪 / 糖代謝 / 骨格筋 / p21 / 細胞周期 / リポクオリティ / 脂肪酸伸長酵素ELOVL / fatty acid / lipid / leukemia / エネルギーセンサー / 脂肪肝炎 / 代謝制御 / ELOLV5 / ELOVL / 淡明型腎細胞癌 / オルガネラリピッドコード / ライブセルイメージング / 酵素 / リピドミクス / オルガネラ / ミトコンドリア / 小胞体 / 多価不飽和脂肪酸 / 発現制御 / Elovl6 / ChREBP / １細胞解析 / 未病 / NASH / 膵臓ラ氏島 / 異質 / 線維化 / SREBP-1 / 膵ラ氏島 / scRNA-seq / 栄養学 / CRISPR/Cas9 / 肝がん / CRISPR/Cas9システム / 腸肝循環 / 脳・神経 / 高次脳機能 / IR52 / insulin signaling / transcription factors / diabetes / Lifestyle-related diseases / Metabolic Syndrome / insulin resistance / IRS-2 / インスリンシグナル / 腸管透過性 / 腸内細菌叢 / ナノメディシン / 骨軟骨代謝 / 骨・軟骨代謝 / ゲノム編集 / 食嗜好性 / 嗜好性 / 横紋筋融解症 / コレステロール代謝 / 疾患関連遺伝子 / ゲノム / 2型糖尿病 / 膵β細胞 / インスリン分泌 / 精神神経疾患 / 胆汁酸 / リポタンパク質 / アデノウイルス / 栄養代謝 / PPARα / ノックアウトマウス / 食欲 / インスリン / グリコーゲン / 脂肪 / cdkインヒビター / 脂肪細胞 / CDK阻害因子 / 脂肪分化 / p27 Less

脂肪酸鎖長制御に基づく代謝性肝疾患の発症予防・治療機序の解明Principal Investigator
- Principal Investigator
  
  松坂賢
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
脂肪酸伸長を起点とする血液脂質学の開拓および白血病治療戦略
- Principal Investigator
  
  千葉滋
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
骨格筋の運動適応における脂肪酸の質の意義の解明Principal Investigator
- Principal Investigator
  
  松坂賢
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Tsukuba
Fatty acid diversity and its sensing mechanism for metabolic control and therapeutic application
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
脂肪酸伸長酵素ELOVLによるリポクオリティ制御を介した腎癌進展メカニズムの解明
- Principal Investigator
  
  新田聡
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Elucidation of the novel regulatory mechanism of mitochondrial function by fatty acids and its application to prevention and treatment of lifestyle-related diseasesPrincipal Investigator
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
Elucidation of the significance of the quality of fatty acids in the bladder cancerPrincipal Investigator
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  University of Tsukuba
The elucidation of renal cell carcinoma progression through ELOVLs-mediated lipid metabolism
- Principal Investigator
  
  Kandori Shuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  University of Tsukuba
Elucidation of the novel mechanism of the fatty acid-induced pancreatic beta-cell proliferation and its application to diabetes treatmentPrincipal Investigator
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Tsukuba
Molecular mechanism of organella homeostasis regulated by quantity and quality of lipids
- Principal Investigator
  
  SHIMANO HITOSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  University of Tsukuba
Elucidation of the molecular mechanism of preventing diabetes onset by the regulation of fatty acid composition and its application for the prevention and treatment of type 2 diabetesPrincipal Investigator
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Tsukuba
Mechanism and prevention strategy of inflammation and fibrosis caused by quantitative and qualitative transformation of organ lipids in inflammation cellular society
- Principal Investigator
  
  Hitoshi Shimano
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Analysis of metabolic diseases targeting nutrient complex associated inflammation caused from enterohepatic circulation
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
The molecular mechanism of organ metabolic disease state and abnormal brain function caused by Elovl6-mediated qualitative changes of fatty acids
- Principal Investigator
  
  Shimano Hitoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Elucidation of the usefulness of the control of fatty acid composition for the prevention of lifestyle-related disease and application to health sciencePrincipal Investigator
- Principal Investigator
  
  Matsuzaka Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Crucial role for Elovl6 during bone development in mice
- Principal Investigator
  
  Shimada Masako
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Sagami Women's University
Anti-atherosclerotic properties of radical-containing nanoparticle
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Fasting-induced transcription factor CREBH ameliorates obesity via entero-hepatic circulation
- Principal Investigator
  
  Nakagawa Yoshimi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Elucidation of the inflammasome regulatory mechanism by fatty acid elongase Elovl6Principal Investigator
- Principal Investigator
  
  MATSUZAKA Takashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Study for tissue specific change of lipid quality and metabolism by fatty acid elongase Elovl6
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
New Conceptual Framework for Copy Number Variation-associated Diabetes
- Principal Investigator
  
  KATAGIRI Hideki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
What are the differences between statin and the shortage of cellular cholesterol content in the pathology of rhabdomyolysis ?
- Principal Investigator
  
  NAKAGAWA Yoshimi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Elucidation of the regulatory mechanism of fatty acid composition in the cell and its role in brain function and mental diseasePrincipal Investigator
- Principal Investigator
  
  MATSUZAKA Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
Evaluation of new nanotechnology to raise HDL cholesterol level and elucidation of its molecular mechanism
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Role of fatty acid elongase Elovl6 in the sucrose preference formationPrincipal Investigator
- Principal Investigator
  
  MATSUZAKA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Role of fatty acid elongase Elovl6 in the sucrose preference formation
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
The molecular mechanism that CREBH activation by nutrition improves metabolic syndrome
- Principal Investigator
  
  NAKAGAWA Yoshimi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  University of Tsukuba
肝臓の脂肪酸組成変化による新規血清LDLコレステロール制御機構の解明
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Control of energy metabolism by changes of the organ lipid quality through fatty acid elongase Elovl6.
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Elucidation of the physiological role of fatty acid elongase Elovl6 in liver and development of new strategy for the treatment of metabolic diseasePrincipal Investigator
- Principal Investigator
  
  MATSUZAKA Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
脂質合成系調節転写因子SREBP-1/2の標的配列特異性を決定する共因子の解明
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Analysis of the pleiotropic effects of TFE3 on metabolic syndrome
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
SREBP2過剰発現マウスによるコレステロール代謝とインスリン分泌の関連の検討
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
CDKインヒビターp21の脂肪細胞分化、肥大化における役割の検討
- Principal Investigator
  
  島野仁
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
新規脂肪酸伸長酵素の生体内における機能ならびに病態への関与Principal Investigator
- Principal Investigator
  
  松坂賢
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
脂質合成転写因子の細胞増殖、細胞周期にもたらす影響に関する検討
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba
Study on a novel energy metabolism transcription factor that regulates insulin signaling
- Principal Investigator
  
  SHIMANO Hitoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba

[Book] Annual Review糖尿病・代謝・内分泌脂肪酸伸長酵素と肥満・インスリン抵抗性2010
- Author(s)
  松坂賢、島野仁
- Total Pages
  7
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Corrigendum: Macrophage SREBP1 regulates skeletal muscle regeneration2024
- Author(s)
  Oishi Yumiko、Koike Hiroyuki、Kumagami Naoki、Nakagawa Yoshimi、Araki Masaya、Taketomi Yoshitaka、Miki Yoshimi、Matsuda Shigeru、Kim Hyeree、Matsuzaka Takashi、Ozawa Hitoshi、Shimano Hitoshi、Murakami Makoto、Manabe Ichiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15
- DOI
  10.3389/fimmu.2024.1382077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00474
[Journal Article] Cross-Sectional and Longitudinal Associations between Forearm Bone Mineral Density and Anthropometry in Adult Japanese Men and Women2024
- Author(s)
  Ishizawa Masahiro、Fujihara Kazuya、Yachida Junko、Ikeda Izumi、Sato Takaaki、Yamada Takaho、Kobayashi Ayako、Tanaka Shiro、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi、Tashiro Minoru、Kodama Satoru、Kato Kiminori、Sone Hirohito
- Journal Title
  
  Journal of Bone Metabolism
  
  Volume: 31 Issue: 1 Pages: 21-30
- DOI
  10.11005/jbm.2024.31.1.21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11569, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K24786
[Journal Article] Macrophage SREBP1 regulates skeletal muscle regeneration2024
- Author(s)
  Oishi Yumiko、Koike Hiroyuki、Kumagami Naoki、Nakagawa Yoshimi、Araki Masaya、Taketomi Yoshitaka、Miki Yoshimi、Matsuda Shigeru、Kim Hyeree、Matsuzaka Takashi、Ozawa Hitoshi、Shimano Hitoshi、Murakami Makoto、Manabe Ichiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1251784-1251784
- DOI
  10.3389/fimmu.2023.1251784
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19534, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03331, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K27603
[Journal Article] Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia2024
- Author(s)
  Furuta Yasuhisa、Osaki Yoshinori、Nakagawa Yoshimi、Han Song-Iee、Araki Masaya、Shikama Akito、Ohuchi Nami、Yamazaki Daichi、Suzuki Hiroaki、Shimano Hitoshi et al.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 31 Issue: 9 Pages: 1304-1318
- DOI
  10.5551/jat.64579
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2024-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19886, KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K23562
[Journal Article] <scp>GR‐KLF15</scp> pathway controls hepatic lipogenesis during fasting2023
- Author(s)
  Takeuchi Y, Murayama Y, Aita Y, Mehrazad Saber Z, Karkoutly S, Tao D, Katabami K, Ye C, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H, Yahagi N.
- Journal Title
  
  The FEBS Journal
  
  Volume: 291 Issue: 2 Pages: 259-271
- DOI
  10.1111/febs.16957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K13900, KAKENHI-PROJECT-23K15405, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K23562
[Journal Article] ELOVL6 deficiency aggravates allergic airway inflammation through the ceramide-S1P pathway in mice2023
- Author(s)
  Yoshida Kazufumi、Morishima Yuko、Ano Satoshi、Sakurai Hirofumi、Kuramoto Kenya、Tsunoda Yoshiya、Yazaki Kai、Nakajima Masayuki、Sherpa Mingma Thering、Matsuyama Masashi、Kiwamoto Takumi、Matsuno Yosuke、Ishii Yukio、Hayashi Akio、Matsuzaka Takashi、Shimano Hitoshi、Hizawa Nobuyuki
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 151 Issue: 4 Pages: 1067-1080.e9
- DOI
  10.1016/j.jaci.2022.12.808
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08197, KAKENHI-PROJECT-22H00474
[Journal Article] Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function2023
- Author(s)
  Sekiya M, Ma Y, Kainoh K, Saito K, Yamazaki D, Tsuyuzaki T, Chen W, Adi Putri PIP, Ohno H, Miyamoto T, Takeuchi Y, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Motomura K, Matsuzaka T, Murata K, Mizuno S, Takahashi S, Shimano H.
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112914-112914
- DOI
  10.1016/j.celrep.2023.112914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis2023
- Author(s)
  Istiqamah Nurani、Matsuzaka Takashi、Shimizu Momo、Motomura Kaori、Ohno Hiroshi、Hasebe Shiho、Sharma Rahul、Okajima Yuka、Matsuda Erika、Han Song-Iee、Mizunoe Yuhei、Osaki Yoshinori、Aita Yuichi、Suzuki Hiroaki、Sone Hirohito、Takeuchi Yoshinori、Sekiya Motohiro、Yahagi Naoya、Nakagawa Yoshimi、Shimano Hitoshi
- Journal Title
  
  BBA Advances
  
  Volume: 3 Pages: 100078-100078
- DOI
  10.1016/j.bbadva.2023.100078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-21H03371
[Journal Article] Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepatitis induced by lipopolysaccharide from Porphyromonas gingivalis through enhanced hepatic clearance.2023
- Author(s)
  K.Chihara, K.Okada, F.Uchida, I.Miura, S.Komine, E.Warabi, T.Takayama, H.Suzuki, T.Matsuzaka, N.Ishibashi-Kanno, K.Yamagata, T.Yanagawa, H.Bukawa, J.Shoda.
- Journal Title
  
  PLoS One
  
  Volume: 18 Issue: 10 Pages: e0291880-e0291880
- DOI
  10.1371/journal.pone.0291880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18282, KAKENHI-PROJECT-23K18321, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K07431, KAKENHI-PROJECT-23K09148, KAKENHI-PROJECT-21K07860, KAKENHI-PROJECT-21K07933, KAKENHI-PROJECT-21K11668, KAKENHI-PROJECT-21H03010, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21H03372
[Journal Article] Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids2023
- Author(s)
  Han Song-Iee、Nakakuki Masanori、Nakagawa Yoshimi、Takeda Hiroyuki、Mizunoe Yuhei、Kainoh Kenta、Murayama Yuki、Aita Yuichi、Takeuchi Yoshinori、Osaki Yoshinori、Miyamoto Takafumi、Sekiya Motohiro、Matsuzaka Takashi、Yahagi Naoya、Sone Hirohito、Daitoku Hiroaki、Sato Ryuichiro、Kawano Hiroyuki、Shimano Hitoshi
- Journal Title
  
  PNAS Nexus
  
  Volume: 2 Issue: 11 Pages: 1-14
- DOI
  10.1093/pnasnexus/pgad351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K19886, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22K17769, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity2023
- Author(s)
  Saito K, Sekiya M, Kainoh K, Yoshino R, Hayashi A, Han SI, Araki M, Ohno H, Takeuchi Y, Tsuyuzaki T, Yamazaki D, Wanpei C, Hada L, Watanabe S, Paramita Adi Putri PI, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Miyamoto T, Matsuzaka T, Shimano H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 7 Pages: 104890-104890
- DOI
  10.1016/j.jbc.2023.104890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward β-Cell Failure2023
- Author(s)
  Motomura K, Matsuzaka T, Shichino S, Ogawa T, Pan H, Nakajima T, Asano Y, Okayama T, Takeuchi T, Ohno H, Han SI, Miyamoto T, Takeuchi Y, Sekiya M, Sone H, Yahagi N, Nakagawa Y, Oda T, Ueha S, Ikeo K, Ogura A, Matsushima K, Shimano H.
- Journal Title
  
  Diabetes
  
  Volume: 73 Issue: 1 Pages: 75-92
- DOI
  10.2337/db23-0212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-22K12043, KAKENHI-PROJECT-22K17769, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K23562
[Journal Article] Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination2023
- Author(s)
  Garcia Corrales AV, Verberk SGS, Haidar M, Grajchen E, Dehairs J, Vanherle S, Loix M, Weytjens T, Gervois P, Matsuzaka T, Lambrichts I, Swinnen JV, Bogie JFJ, Hendriks JJA.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 37
- DOI
  10.1073/pnas.2301030120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-21H03371
[Journal Article] The fatty acid elongase Elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation2023
- Author(s)
  Kiyoki Yusuke、Kato Takayasu、Kito Sakura、Matsuzaka Takashi、Morioka Shin、Sasaki Junko、Makishima Kenichi、Sakamoto Tatsuhiro、Nishikii Hidekazu、Obara Naoshi、Sakata-Yanagimoto Mamiko、Sasaki Takehiko、Shimano Hitoshi、Chiba Shigeru
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 4 Pages: 910-913
- DOI
  10.1038/s41375-023-01842-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16261, KAKENHI-PROJECT-20K08724, KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-21H02680, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-23K27319
[Journal Article] ELOVL5-mediated fatty acid elongation promotes cellular proliferation and invasion in renal cell carcinoma2022
- Author(s)
  Nitta Satoshi、Kandori Shuya、Tanaka Ken、Sakka Shotaro、Siga Masanobu、Nagumo Yoshiyuki、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan J.、Shimazui Toru、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi、Nishiyama Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 8 Pages: 2738-2752
- DOI
  10.1111/cas.15454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09517, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562
[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice2022
- Author(s)
  Okajima Yuka、Matsuzaka Takashi、Miyazaki Shun、Motomura Kaori、Ohno Hiroshi、Sharma Rahul、Shimura Takuya、Istiqamah Nurani、Han Song-iee、Mizunoe Yuhei、Osaki Yoshinori、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sone Hirohito、Miyamoto Takafumi、Aita Yuichi、Takeuchi Yoshinori、Sekiya Motohiro、Shimano Hitoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1868 Issue: 4 Pages: 166339-166339
- DOI
  10.1016/j.bbadis.2022.166339
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-23K23562
[Journal Article] Wogonin, a Compound in Scutellaria baicalensis, Activates ATF4?FGF21 Signaling in Mouse Hepatocyte AML12 Cells2022
- Author(s)
  Yamada Yasunari、Saito Hodaka、Araki Masaya、Tsuchimoto Yuhei、Muroi Shin-ichi、Suzuki Kyohei、Toume Kazufumi、Kim Jun-Dal、Matsuzaka Takashi、Sone Hirohito、Shimano Hitoshi、Nakagawa Yoshimi
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 19 Pages: 3920-3920
- DOI
  10.3390/nu14193920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06626, KAKENHI-PROJECT-22K20957, KAKENHI-PROJECT-22K21200, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-23K24786
[Journal Article] CREBH regulation of lipid metabolism through multifaceted functions that improve arteriosclerosis.2022
- Author(s)
  Nakagawa Y, Matsuzaka T, Shimano H.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: Feb 5. Issue: 7 Pages: 1129-1131
- DOI
  10.1111/jdi.13766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21H03371
[Journal Article] Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice.2022
- Author(s)
  Okajima Y, Matsuzaka T, Miyazaki S, Motomura K, Ohno H, Sharma R, Shimura T, Istiqamah N, Han SI, Mizunoe Y, Osaki Y, Iwasaki H, Yatoh S, Suzuki H, Sone H, Miyamoto T, Aita Y, Takeuchi Y, Sekiya M, Yahagi N, Nakagawa Y, Tomita T, Shimano H.
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis.
  
  Volume: 1868(4) Pages: 166339-166339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21643
[Journal Article] A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction.2022
- Author(s)
  Nakajima R, Sekiya M, Furuta Y, Miyamoto T, Sato M, Fukuda K, et, al.
- Journal Title
  
  Endocrinol Diabetes Metab Case Rep.
  
  Volume: 22 Pages: 0368-0368
- DOI
  10.1530/edm-22-0368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08072, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-20K08855, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-23K21443, KAKENHI-PROJECT-23K23562, KAKENHI-PROJECT-21K16262
[Journal Article] Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques2022
- Author(s)
  Nagatake T, Kishino S, Urano E, et al.
- Journal Title
  
  Mucosal Immunology
  
  Volume: 15 Issue: 2 Pages: 289-300
- DOI
  10.1038/s41385-021-00477-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07617, KAKENHI-PROJECT-20K21643, KAKENHI-WRAPUP-20H05613, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-22K15004, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-21H02757
[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition2021
- Author(s)
  Nakagawa Yoshimi、Wang Yunong、Han Song-iee、Okuda Kanako、Oishi Asayo、Yagishita Yuka、Kumagai Kae、Ohno Hiroshi、Osaki Yoshinori、Mizunoe Yuhei、Araki Masaya、Murayama Yuki、Iwasaki Hitoshi、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 4 Pages: 949-971
- DOI
  10.1016/j.jcmgh.2020.11.004
- NAID
  120006939158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-18KT0065, KAKENHI-PROJECT-21H04861
[Journal Article] High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways2021
- Author(s)
  Mehrazad Saber Zahra、Takeuchi Yoshinori、Sawada Yoshikazu、Aita Yuichi、Ho Man Hei、Karkoutly Samia、Tao Duhan、Katabami Kyoka、Ye Chen、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Miyamoto Takafumi、Matsuzaka Takashi、Sugasawa Takehito、Takekoshi Kazuhiro、Kawakami Yasushi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 582 Pages: 35-42
- DOI
  10.1016/j.bbrc.2021.10.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-19K20175, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Rapid manipulation of mitochondrial morphology in a living cell with iCMM2021
- Author(s)
  Miyamoto Takafumi、Uosaki Hideki、Mizunoe Yuhei、Han Song-Iee、Goto Satoi、Yamanaka Daisuke、Masuda Masato、Yoneyama Yosuke、Nakamura Hideki、Hattori Naoko、Takeuchi Yoshinori、Ohno Hiroshi、Sekiya Motohiro、Matsuzaka Takashi、Hakuno Fumihiko、Takahashi Shin-Ichiro、Yahagi Naoya、Ito Koichi、Shimano Hitoshi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 1 Issue: 4 Pages: 100052-100052
- DOI
  10.1016/j.crmeth.2021.100052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K16536, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19KK0219, KAKENHI-PROJECT-23K23562
[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin.2021
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Mehrazad-Saber Z, Ho MH, Huyan Y, Murayama Y, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H.
- Journal Title
  
  iScience.
  
  Volume: 24(12) Pages: 103446-103446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21643
[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin.2021
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Mehrazad-Saber Z, Ho MH, Huyan Y, Murayama Y, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H.
- Journal Title
  
  iScience.
  
  Volume: 24(12) Pages: 103446-103446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06395
[Journal Article] Starvation‐induced transcription factor CREBH negatively governs body growth by controlling GH signaling2021
- Author(s)
  Nakagawa Yoshimi、Kumagai Kae、Han Song‐iee、Mizunoe Yuhei、Araki Masaya、Mizuno Seiya、Ohno Hiroshi、Matsuo Kazuya、Yamada Yasunari、Kim Jun‐dal、Miyamoto Takafumi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Takahashi Satoru、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 6 Pages: 21663-21663
- DOI
  10.1096/fj.202002784rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05429, KAKENHI-PROJECT-19K07095, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H04861, KAKENHI-PROJECT-21J11045, KAKENHI-PROJECT-21K19064
[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin.2021
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Mehrazad-Saber Z, Ho MH, Huyan Y, Murayama Y, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H.
- Journal Title
  
  iScience.
  
  Volume: 24(12) Pages: 103446-103446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03371
[Journal Article] ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma2021
- Author(s)
  Tanaka Ken、Kandori Shuya、Sakka Shotaro、Nitta Satoshi、Tanuma Kozaburo、Shiga Masanobu、Nagumo Yoshiyuki、Negoro Hiromitsu、Kojima Takahiro、Mathis Bryan、Shimazui Toru、Watanabe Makoto、Sato Taka-Aki、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi、Nishiyama Hiroyuki
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 2 Pages: 23-23
- DOI
  10.3892/or.2021.8234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis2021
- Author(s)
  Sekiya Motohiro、Kainoh Kenta、Sugasawa Takehito、Yoshino Ryunosuke、Hirokawa Takatsugu、Tokiwa Hiroaki、Nakano Shogo、Nagatoishi Satoru、Tsumoto Kouhei、Takeuchi Yoshinori、Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41467-021-26638-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-20H02531
[Journal Article] CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF22021
- Author(s)
  Kainoh Kenta、Takano Ryo、Sekiya Motohiro、Saito Kenji、Sugasawa Takehito、Ma Yang、Murayama Yuki、Sugano Yoko、Osaki Yoshinori、Iwasaki Hitoshi、Takeuchi Yoshinori、Yahagi Naoya、Suzuki Hiroaki、Miyamoto Takafumi、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 562 Pages: 146-153
- DOI
  10.1016/j.bbrc.2021.05.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Macrophages rely on extracellular serine to suppress aberrant cytokine production2021
- Author(s)
  Kurita Kento、Ohta Hiroya、Shirakawa Ibuki、Tanaka Miyako、Kitaura Yasuyuki、Iwasaki Yorihiro、Matsuzaka Takashi、Shimano Hitoshi、Aoe Seiichiro、Arima Hiroshi、Ogawa Yoshihiro、Ito Ayaka、Suganami Takayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11137-11137
- DOI
  10.1038/s41598-021-90086-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11765, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-20H04944, KAKENHI-PUBLICLY-20H05503, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-20K07094, KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-19KK0249
[Journal Article] Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis.2021
- Author(s)
  Koguchi-Yoshioka H, Watanabe R, Matsumura Y, Ishitsuka Y, Inoue S, Furuta J, Nakamura Y, Okiyama N, Matsuzaka T, Shimano H, Fujisawa Y, Fujimoto M.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 103(2) Issue: 2 Pages: 109-115
- DOI
  10.1016/j.jdermsci.2021.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371
[Journal Article] 脂肪酸による膵β細胞増殖作用2020
- Author(s)
  本村香織、松坂賢
- Journal Title
  
  Medical Science Digest
  
  Volume: 46(1) Pages: 64-66
- Data Source
  KAKENHI-PROJECT-18K19724
[Journal Article] A new perspective on type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease.2020
- Author(s)
  Matsuzaka T, Shimano H.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: in press Issue: 3 Pages: 532-534
- DOI
  10.1111/jdi.13258
- NAID
  120007165450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395
[Journal Article] Bladder preservation therapy for muscle invasive bladder cancer: the past, present and future2020
- Author(s)
  Kimura Tomokazu、Ishikawa Hitoshi、Kojima Takahiro、Kandori Shuya、Kawahara Takashi、Sekino Yuta、Sakurai Hideyuki、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 10 Pages: 1097-1107
- DOI
  10.1093/jjco/hyaa155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-18K09158
[Journal Article] Role of fatty acid elongase Elovl6 in the regulation of energy metabolism and pathophysiological significance in diabetes.2020
- Author(s)
  Matsuzaka T.
- Journal Title
  
  Diabetol Int.
  
  Volume: 12(1) Issue: 1 Pages: 68-73
- DOI
  10.1007/s13340-020-00481-3
- NAID
  130007992492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21643, KAKENHI-PROJECT-18H03189
[Journal Article] Prognostic significance of non-urothelial carcinoma of bladder: analysis of nationwide hospital-based cancer registry data in Japan2020
- Author(s)
  Nagumo Yoshiyuki、Kawai Koji、Kojima Takahiro、Shiga Masanobu、Kojo Kosuke、Tanaka Ken、Kandori Shuya、Kimura Tomokazu、Kawahara Takashi、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 9 Pages: 1068-1075
- DOI
  10.1093/jjco/hyaa072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-19K09705, KAKENHI-PROJECT-18K09158
[Journal Article] CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms2020
- Author(s)
  Satoh Aoi、Han Song-iee、Araki Masaya、Nakagawa Yoshimi、Ohno Hiroshi、Mizunoe Yuhei、Kumagai Kae、Murayama Yuki、Osaki Yoshinori、Iwasaki Hitoshi、Sekiya Motohiro、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Shimano Hitoshi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100930-100930
- DOI
  10.1016/j.isci.2020.100930
- NAID
  120006891020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07095, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-19H00449, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18KT0065
[Journal Article] Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non‐alcoholic steatohepatitis model2020
- Author(s)
  Shimizu Yoshio、Tamura Takafumi、Kemmochi Akira、Owada Yohei、Ozawa Yusuke、Hisakura Katsuji、Matsuzaka Takashi、Shimano Hitoshi、Nakano Noriyuki、Sakashita Shingo、Oda Tatsuya、Ohkohchi Nobuhiro
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 36 Issue: 3 Pages: 800-810
- DOI
  10.1111/jgh.15239
- NAID
  120007165441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-19K09162
[Journal Article] Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT12020
- Author(s)
  Ma Yang、Sekiya Motohiro、Kainoh Kenta、Matsuda Takaaki、Iwasaki Hitoshi、Osaki Yoshinori、Sugano Yoko、Suzuki Hiroaki、Takeuchi Yoshinori、Miyamoto Takafumi、Yahagi Naoya、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Issue: 2 Pages: 354-360
- DOI
  10.1016/j.bbrc.2019.12.070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-18K06206
[Journal Article] Recent malignant testicular tumor trend in Japan, a country with an aging population: a large-scale study of 2012?2015 hospital-based cancer registry data2020
- Author(s)
  Kojo Kosuke、Kawai Koji、Kawahara Takashi、Kimura Tomokazu、Kandori Shuya、Nagumo Yoshiyuki、Nitta Satoshi、Kojima Takahiro、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 10 Pages: 1201-1208
- DOI
  10.1093/jjco/hyaa110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-17H03589, KAKENHI-PROJECT-18K09158
[Journal Article] Prognostic impact of non‐urothelial carcinoma of the upper urinary tract: Analysis of hospital‐based cancer registry data in Japan2020
- Author(s)
  Nagumo Yoshiyuki、Kawai Koji、Kojima Takahiro、Shiga Masanobu、Kojo Kosuke、Tanaka Ken、Kandori Shuya、Kimura Tomokazu、Kawahara Takashi、Okuyama Ayako、Higashi Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  International Journal of Urology
  
  Volume: 28 Issue: 1 Pages: 54-60
- DOI
  10.1111/iju.14393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664, KAKENHI-PROJECT-18K09158
[Journal Article] Predictors of venous thromboembolism development before and during chemotherapy for advanced germ cell tumor2020
- Author(s)
  Nitta Satoshi、Kawai Koji、Kimura Tomokazu、Kawahara Takashi、Kandori Shuya、Hoshi Akio、Kojima Takahiro、Nishiyama Hiroyuki
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 50 Issue: 3 Pages: 338-343
- DOI
  10.1093/jjco/hyz177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09664
[Journal Article] Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl‐Chain Length and Hepatic Insulin Sensitivity in Mice2020
- Author(s)
  Matsuzaka T、Kuba M、Koyasu S、Yamamoto Y、Motomura K、Arulmozhiraja S、Ohno H、Sharma R、Shimura T、Okajima Y、Han SI、Aita Y、Mizunoe Y、Osaki Y、Iwasaki H、Yatoh S、Suzuki H、Sone H、Takeuchi Y、Yahagi N、Miyamoto T、Sekiya M、Nakagawa Y、Ema M、Takahashi S、Tokiwa H、Shimano H
- Journal Title
  
  Hepatology
  
  Volume: 71 Issue: 5 Pages: 1609-1625
- DOI
  10.1002/hep.30953
- NAID
  120007132717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20175, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-18K19724, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K21611, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18K06206
[Journal Article] ROCK 1 as a new player in the regulation of hepatic lipogenesis2019
- Author(s)
  Miyamoto Takafumi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 5 Pages: 1165-1167
- DOI
  10.1111/jdi.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18K19724
[Journal Article] TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer2019
- Author(s)
  Kawahara Takashi、Kojima Takahiro、Kandori Shuya、Kurobe Masahiro、Yoshino Takayuki、Kimura Tomokazu、Nagumo Yoshiyuki、Ishituka Ryutaro、Mitsuzuka Koji、Narita Shintaro、Kobayashi Takashi、Matsui Yoshiyuki、Ogawa Osamu、Sugimoto Mikio、Miyazaki Jun、Nishiyama Hiroyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: 220173-220173
- DOI
  10.1371/journal.pone.0220173
- NAID
  120007133062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09158, KAKENHI-PROJECT-19K09664
[Journal Article] Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex2019
- Author(s)
  Murayama Yuki, Takafumi Miyamoto, et al.
- Journal Title
  
  FEBS Letters
  
  Volume: 593 Issue: 4 Pages: 423-432
- DOI
  10.1002/1873-3468.13328
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17K12895, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H05060, KAKENHI-PROJECT-17K00846
[Journal Article] Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism2019
- Author(s)
  Sharma Rahu, Takafumi Miyamoto, et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5169-5169
- DOI
  10.1038/s41598-019-41631-1
- NAID
  120007133465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06206, KAKENHI-PROJECT-18K19724, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H04854, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.2018
- Author(s)
  Piao X, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 592(3) Pages: 422-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03093
[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018
- Author(s)
  Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 4 Pages: 744-756
- DOI
  10.1161/atvbaha.117.310581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice2018
- Author(s)
  Araki Masaya、Nakagawa Yoshimi、Oishi Asayo、Han Song-iee、Wang Yunong、Kumagai Kae、Ohno Hiroshi、Mizunoe Yuhei、Iwasaki Hitoshi、Sekiya Motohiro、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 7 Pages: 2148-2148
- DOI
  10.3390/ijms19072148
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811
[Journal Article] Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features.2018
- Author(s)
  Owada Y, Tamura T, Tanoi T, Ozawa Y, Shimizu Y, Hisakura K, Matsuzaka T, Shimano H, Nakano N, Sakashita S, Matsukawa T, Isoda H, Ohkohchi N.
- Journal Title
  
  Pathol Int.
  
  Volume: 68(1) Issue: 1 Pages: 12-22
- DOI
  10.1111/pin.12612
- NAID
  120007134624
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093
[Journal Article] Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.2018
- Author(s)
  Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H.
- Journal Title
  
  Endocrinology.
  
  Volume: 159(6) Issue: 6 Pages: 2308-2323
- DOI
  10.1210/en.2017-03179
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-17H05060
[Journal Article] Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα2018
- Author(s)
  Yamamoto Yuta、Takei Kenta、Arulmozhiraja Sundaram、Sladek Vladimir、Matsuo Naoya、Han Song-iee、Matsuzaka Takashi、Sekiya Motohiro、Tokiwa Takaki、Shoji Mitsuo、Shigeta Yasuteru、Nakagawa Yoshimi、Tokiwa Hiroaki、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 499 Issue: 2 Pages: 239-245
- DOI
  10.1016/j.bbrc.2018.03.135
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0010, KAKENHI-PROJECT-16H03253, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16K01811
[Journal Article] A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.2018
- Author(s)
  Piao X, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 592(3) Issue: 3 Pages: 422-433
- DOI
  10.1002/1873-3468.12975
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H05060
[Journal Article] Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation.2018
- Author(s)
  Nakamura Y, Matsuzaka T, Tahara-Hanaoka S, Shibuya K, Shimano H, Nakahashi-Oda C, Shibuya A.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 9(12) Issue: 12 Pages: 1181-1181
- DOI
  10.1038/s41419-018-1226-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05169, KAKENHI-PROJECT-17H04362, KAKENHI-PROJECT-18H03189, KAKENHI-PUBLICLY-17H05495, KAKENHI-PROJECT-16H05350, KAKENHI-PROJECT-17K19541
[Journal Article] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling2017
- Author(s)
  Muranaka H、Hayashi A、Minami K、Kitajima S、Kohno S、Nishimoto Y、Nagatani N、Suzuki M、Kulathunga L A N、Sasaki N、Okada N、Matsuzaka T、Shimano H、Tada H、Takahashi C
- Journal Title
  
  Oncogenesis
  
  Volume: 6 Issue: 6 Pages: e350-e350
- DOI
  10.1038/oncsis.2017.51
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.2017
- Author(s)
  Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H.
- Journal Title
  
  FEBS Lett
  
  Volume: 591 Issue: 7 Pages: 965-978
- DOI
  10.1002/1873-3468.12620
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-17K13217, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17H05060
[Journal Article] SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism.2017
- Author(s)
  Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK.
- Journal Title
  
  Cell Metab.
  
  Volume: 25(2) Issue: 2 Pages: 412-427
- DOI
  10.1016/j.cmet.2016.11.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16H05295, KAKENHI-PROJECT-26461142
[Journal Article] Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.2017
- Author(s)
  Takei K, Nakagawa Y, Wang Y, Han SI, Satoh A, Sekiya M, Matsuzaka T, Shimano H.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 印刷中 Issue: 4 Pages: 214-222
- DOI
  10.1016/j.jphs.2017.02.003
- NAID
  120007128987
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253
[Journal Article] Elovl6 Deficiency Improves Glycemic Control in Diabetic db / db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity2017
- Author(s)
  Zhao Hui、Matsuzaka Takashi、Nakano Yuta、Motomura Kaori、Tang Nie、Yokoo Tomotaka、Okajima Yuka、Han Song-iee、Takeuchi Yoshinori、Aita Yuichi、Iwasaki Hitoshi、Yatoh Shigeru、Suzuki Hiroaki、Sekiya Motohiro、Yahagi Naoya、Nakagawa Yoshimi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Diabetes
  
  Volume: 66 Issue: 7 Pages: 1833-1846
- DOI
  10.2337/db16-1277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17H05060
[Journal Article] The selective PPARα modulator K-877 efficiently activates the PPARα pathway and improves lipid metabolism in mice2017
- Author(s)
  Takei K, Han SI, Murayama Y, Satoh A, Oikawa F, Ohno H, Osaki Y, Matsuzaka T, Sekiya M, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Yamada N, Nakagawa Y, Shimano H.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 4 Pages: 446-452
- DOI
  10.1111/jdi.12621
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K09738, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040
[Journal Article] Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry2017
- Author(s)
  Sawada Yoshikazu、Izumida Yoshihiko、Takeuchi Yoshinori、Aita Yuichi、Wada Nobuhiro、Li EnXu、Murayama Yuki、Piao Xianying、Shikama Akito、Masuda Yukari、Nishi-Tatsumi Makiko、Kubota Midori、Sekiya Motohiro、Matsuzaka Takashi、Nakagawa Yoshimi、Shimano Hitoshi、Yahagi Naoya
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 493 Issue: 1 Pages: 40-45
- DOI
  10.1016/j.bbrc.2017.09.081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K13217, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-17H05060
[Journal Article] Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.2016
- Author(s)
  Nakagawa Y, Oikawa F, Ohno H, Yagishita Y, Satoh A, Osaki Y, Takei K, Kikuchi T, Song-iee H, Mizuno S. Matsuzaka T, Iwasaki H, Kobayashi K, Yatoh S, Yahagi N, Suzuki H, Sone H, Takahashi S, Yamada N, Shimano H.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 27857-27857
- DOI
  10.1038/srep27857
- NAID
  120007135376
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-26500001, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-16H06276
[Journal Article] Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.2016
- Author(s)
  Suzuki-Kemuriyama N, Matsuzaka T, Kuba M, Ohno H, Han SI, Takeuchi Y, Isaka M, Kobayashi K, Iwasaki H, Yatoh S, Suzuki H, Miyajima K, Nakae D, Yahagi N, Nakagawa Y, Sone H, Yamada N, Shimano H.
- Journal Title
  
  PLoS One.
  
  Volume: 11(6) Issue: 6 Pages: e0157580-e0157580
- DOI
  10.1371/journal.pone.0157580
- NAID
  120007135350
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.2016
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Murayama Y, Sawada Y, Piao X, Toya N, Oya Y, Shikama A, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Yamamoto T, Sekiya M, Matsuzaka T, Nakagawa Y, Urayama O, Kawakami Y, Iizuka Y, Gotoda T, Itaka K, Kataoka K, Nagai R, Kadowaki T, Yamada N, Lu Y, Jain MK, and Shimano H
- Journal Title
  
  Cell Rep.
  
  Volume: 16 Issue: 9 Pages: 2373-2386
- DOI
  10.1016/j.celrep.2016.07.069
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-15H04824, KAKENHI-PROJECT-26461357, KAKENHI-PROJECT-16K13040
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Mol Metab.
  
  Volume: 5(11) Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02541
[Journal Article] Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Kruppel-Like Factor 4 (AMPK/KLF4) Signaling.2016
- Author(s)
  Sunaga H, Matsui H, Anjo S, Syamsunarno MR, Koitabashi N, Iso T, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5(12)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02541
[Journal Article] Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.2016
- Author(s)
  5.Kikuchi T, Orihara K, Oikawa F, Han SI, Kuba M, Okuda K, Satoh A, Osaki Y, Takeuchi Y, Aita Y, Matsuzaka T, Iwasaki H, Yatoh S, Sekiya M, Yahagi N, Suzuki H, Sone H, Nakagawa Y, Yamada N, Shimano H.
- Journal Title
  
  Molecular Metabolism
  
  Volume: 5 Pages: 1092-1102
- NAID
  120007129266
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H03253
[Journal Article] Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice.2016
- Author(s)
  Kikuchi M, Shimada M, Matsuzaka T, Ishii K, Nakagawa Y, Takayanagi M, Yamada N, Shimano H.
- Journal Title
  
  PLoS One.
  
  Volume: 11(7) Issue: 7 Pages: e0159375-e0159375
- DOI
  10.1371/journal.pone.0159375
- NAID
  120007129433
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-26461377, KAKENHI-PROJECT-26560393
[Journal Article] CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.2016
- Author(s)
  Nakagawa Y, Satoh A, Tezuka H, Han SI, Takei K, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Iwasaki Y, Sone H, Matsuzaka T, Yamada N, Shimano H.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 39182-39182
- DOI
  10.1038/srep39182
- NAID
  120007135285
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-15K09436, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040
[Journal Article] Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Kruppel-Like Factor 4 (AMPK/KLF4) Signaling.2016
- Author(s)
  Sunaga H, Matsui H, Anjo S, Syamsunarno MR, Koitabashi N, Iso T, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5(12)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03093
[Journal Article] 1,8-cineole ameliorates steatosis of Pten liver specific KO mice via Akt inactivation.2015
- Author(s)
  Soichiro Murata, Koichi Ogawa, Takashi Matsuzaka, Mitsuru Chiba, Ken Nakayama, Kenichi Iwasaki, Tomohiro Kurokawa, Naoki Sano, Tomohito Tanoi, Nobuhiro Ohkohchi.
- Journal Title
  
  International Journal of Molecular Sciences.
  
  Volume: 16 Issue: 6 Pages: 12051-63
- DOI
  10.3390/ijms160612051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03093
[Journal Article] Identification of human ELOVL5 enhancer regions controlled by SREBP.2015
- Author(s)
  Shikama A, Shinozaki H, Takeuchi Y, Matsuzaka T, Aita Y, Murayama T, Sawada Y, Piao X, Toya N, Oya Y, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Yamada N, Shimano H, Yahagi N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 465(4) Issue: 4 Pages: 857-63
- DOI
  10.1016/j.bbrc.2015.08.101
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-25461332, KAKENHI-PROJECT-26560392, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy.2015
- Author(s)
  Osaki Y, Nakagawa Y, Miyahara S, Iwasaki H, Ishii A, Matsuzaka T, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Sone H, Ohashi K, Ishibashi S, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 466(3) Issue: 3 Pages: 536-540
- DOI
  10.1016/j.bbrc.2015.09.065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15344, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-13J00607, KAKENHI-PROJECT-26560391, KAKENHI-PROJECT-26560392, KAKENHI-PROJECT-25293213, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a2015
- Author(s)
  Kuba M, Matsuzaka T, Matsumori R, Saito R, Kaga N, Taka H, Ikehata K, Okada N,
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 17604-17604
- DOI
  10.1038/srep17604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-26882008, KAKENHI-PROJECT-25430140, KAKENHI-PROJECT-26560392, KAKENHI-PROJECT-26800271, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-15H03092
[Journal Article] Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.2014
- Author(s)
  Tang N, Matsuzaka T, Suzuki M, Nakano Y, Zao H, Yokoo T, Suzuki-Kemuriyama N, Kuba M, Okajima Y, Takeuchi Y, Kobayashi K, Iwasaki H, Yatoh S, Takahashi A, Suzuki H, Sone H, Shimada M, Nakagawa Y, Yahagi N, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450(1) Issue: 1 Pages: 318-23
- DOI
  10.1016/j.bbrc.2014.05.113
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25670430, KAKENHI-PROJECT-26670448, KAKENHI-PLANNED-23116006
[Journal Article] New liver-β-cell axis that controls insulin secretory capacity.2014
- Author(s)
  Matsuzaka T, Shimano H.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 5(3) Issue: 3 Pages: 276-7
- DOI
  10.1111/jdi.12199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24680072, KAKENHI-PROJECT-25670430
[Journal Article] Hepatic CREB3L3 Controls Whole-Body Energy Homeostasis and Improves Obesity and Diabetes2014
- Author(s)
  Yoshimi Nakagawa,* Aoi Satoh,* Sachiko Yabe,* Mika Furusawa, Naoko Tokushige, Hitomi Tezuka, Motoki Mikami, Wakiko Iwata, Akiko Shingyouchi, Takashi Matsuzaka, Shiori Kiwata, Yuri Fujimoto, Yasushi Kawakami, Osamu Urayama, Nobuhiro Yamada, and Hitoshi Shimano et. al
- Journal Title
  
  Endocrinology
  
  Volume: 155(12) Issue: 12 Pages: 4706-4719
- DOI
  10.1210/en.2014-1113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J00094, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25282214, KAKENHI-PROJECT-25670430, KAKENHI-PROJECT-26670448, KAKENHI-PLANNED-23116006
[Journal Article] TFE3 inhibits myoblast differentiation inC2C12 cells via down-regulating geneexpression of myogenin2013
- Author(s)
  Naka A, Iida KT, Nakagawa Y, IwasakiH, Takeuchi Y, Satoh A, Matsuzaka T, IshiiKA, Kobayashi K, Yatoh S, Shimada M, YahagiN, Suzuki H, Sone H, Yamada N, Shimano H
- Journal Title
  
  Biochem BiophysRes Commun
  
  Volume: 430 Pages: 664-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.2013
- Author(s)
  Naka A, Iida K, Nakagawa Y, Iwasaki H, Takeuchi Y, Satoh A, Matsuzaka T, Ishii KA, Kobayashi K, Yatoh S, Shimada M, Yahagi N, Suzuki H, Sone H, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization.2013
- Author(s)
  Izumida Y, Yahagi N, Takeuchi Y, Nishi M, Shikama A, Takarada A, Masuda Y, Kubota M, Matsuzaka T, Nakagawa Y, Iizuka Y, Itaka K, Kataoka K, Shioda S, Niijima A, Yamada T, Katagiri H, Nagai R, Yamada N, Kadowaki T, Shimano H
- Journal Title
  
  Nat Commun.
  
  Volume: 4 Issue: 1 Pages: 2316-2316
- DOI
  10.1038/ncomms3316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126004, KAKENHI-PLANNED-22126006, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23591293, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659439, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461332, KAKENHI-PROJECT-25670430
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis in mice and humans.2013
- Author(s)
  Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A, Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H.
- Journal Title
  
  Hepatology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis.2013
- Author(s)
  Fujimoto Y, Nakagawa Y, Satoh A, Okuda K, Shingyouchi A, Naka A, Matsuzaka T, Iwasaki H, Kobayashi K, Yahagi N, Shimada M, Yatoh S, Suzuki H, Yogosawa S, Izumi T, Sone H, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Endocrinology
  
  Volume: 154 Issue: 10 Pages: 3577-88
- DOI
  10.1210/en.2013-1203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-24300233, KAKENHI-PROJECT-24390068, KAKENHI-PROJECT-24659442, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126702, KAKENHI-PROJECT-25670430
[Journal Article] TFE3 inhibits myoblast diffrentiation in C2C12 cells via down-regulating gene expression of myogenin.2013
- Author(s)
  Naka A, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 430 Issue: 2 Pages: 664-669
- DOI
  10.1016/j.bbrc.2012.11.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-10J01029, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23659473, KAKENHI-PROJECT-24300233, KAKENHI-PROJECT-24300254, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659440, KAKENHI-PROJECT-24659441
[Journal Article] TFE3 inhibits myoblast differentiation inC2C12 cells via down-regulating geneexpression of myogenin2013
- Author(s)
  Naka A, Iida KT, Nakagawa Y, IwasakiH, Takeuchi Y, Satoh A, Matsuzaka T, IshiiKA, Kobayashi K, Yatoh S, Shimada M, YahagiN, Suzuki H, Sone H, Yamada N, Shimano H
- Journal Title
  
  Biochem BiophysRes Commun
  
  Volume: 430(2) Pages: 664-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice2013
- Author(s)
  Sunaga Hiroaki, Kurabayashi Masahiko
- Journal Title
  
  Nature Communications
  
  Volume: vol.4 Issue: 1 Pages: 2563-2563
- DOI
  10.1038/ncomms3563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590661, KAKENHI-PROJECT-23790656, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24592730, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25504002, KAKENHI-PROJECT-25670430
[Journal Article] regulates muscle metabolic geneexpression, increases glycogen stores,and enhances insulin sensitivity in mice.2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, NakagawaY, Matsuzaka T, Ishii KA, Kobayashi K,Takahashi A, Yatoh S, Yahagi N, Sone H,Suzuki H, Yamada N, Shimano H
- Volume
  302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Matsuzaka T, Shimano H, et al
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis2012
- Author(s)
  Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A,Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H
- Journal Title
  
  Hepatology
  
  Volume: 56(6) Pages: 2199-2208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells.2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A, Tokushige N, Nakanishi N, Satoh A, Matsuzaka T, Ishii KA, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yahagi N, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420 Issue: 4 Pages: 931-6
- DOI
  10.1016/j.bbrc.2012.03.110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659441
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7) Pages: 896-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] TFE3 reg ulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances in sulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis2012
- Author(s)
  Takashi Matsuzaka, et al
- Journal Title
  
  Hepatology
  
  Volume: 56 Issue: 6 Pages: 2199-2208
- DOI
  10.1002/hep.25932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00911, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23659464, KAKENHI-PROJECT-23659473, KAKENHI-PROJECT-23791480, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659441, KAKENHI-PROJECT-24680072
[Journal Article] Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Matsuzaka T, Shimano H, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] TFE3 Regulates Muscle Metabolic Gene Expression, Increases Glycogen Stores, and Enhances Insulin Sensitivity in Mice.2012
- Author(s)
  Iwasaki H, Naka A, Iida K, Nakagawa Y, Matsuzaka T, Ishii KA, Kobayashi K, Takahashi A, Yatoh S, Yahagi N, Sone H, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Matsuzaka T, Shimano H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Dicer hasa crucial role in the early stage ofadipocyte differentiation, but not inlipid synthesis, in 3T3-L1 cells2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A,Tokushige N, Nakanishi N, Satoh A,Matsuzaka T, Ishii KA, Iwasaki H,Kobayashi K, Yatoh S, Suzuki H, Yahagi N,Urayama O, Yamada N, Shimano H
- Journal Title
  
  BiochemBiophys Res Commun
  
  Volume: 420(4) Pages: 931-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659441
[Journal Article] Dicer hasa crucial role in the early stage ofadipocyte differentiation, but not inlipid synthesis, in 3T3-L1 cells2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A,Tokushige N, Nakanishi N, Satoh A,Matsuzaka T, Ishii KA, Iwasaki H,Kobayashi K, Yatoh S, Suzuki H, Yahagi N,Urayama O, Yamada N, Shimano H
- Journal Title
  
  BiochemBiophys Res Commun
  
  Volume: 420 Pages: 931-936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] Elovl6 promotes nonalcoholic steatohepatitis.2012
- Author(s)
  Matsuzaka T, Atsumi A, Matsumori R, Nie T, Shinozaki H, Suzuki-Kemuriyama N, Kuba M, Nakagawa Y, Ishii K, Shimada M, Kobayashi K, Yatoh S, Takahashi A,Takekoshi K, Sone H, Yahagi N, Suzuki H, Murata S, Nakamuta M, Yamada N, Shimano H
- Journal Title
  
  Hepatology.
  
  Volume: 56 Pages: 2199-2208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice2012
- Author(s)
  Iwasaki H, Naka A, Matsuzaka T, Shimano H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] TFE3regulates muscle metabolic geneexpression2012
- Author(s)
  Iwasaki H, Naka A, Iida KT, NakagawaY, Matsuzaka T, Ishii KA, Kobayashi K,Takahashi A, Yatoh S, Yahagi N, Sone H,Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  increases glycogen stores,and enhances insulin sensitivity in mice
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells.2012
- Author(s)
  Fujimoto Y, Nakagawa Y, Shingyouchi A, Tokushige N, Nakanishi N, Satoh A, Matsuzaka T, Ishii KA, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yahagi N, Urayama O, Yamada N, Shimano H.
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  Biochem Biophys Res Commun.
  
  Volume: 420(4) Pages: 931-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7a (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5 (KLF5)/p eroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(9) Pages: 1973-9
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- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
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  Saito R, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  Arterioscler Thromb Vase Biol.
  
  Volume: 31(9) Pages: 1973-9
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  KAKENHI-PROJECT-21390275
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoprotein sand accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7 α (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5 (KLF5)/p eroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.2011
- Author(s)
  Kumadaki S, Matsuzaka T, Yamada N, Shimano H, et al.
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  J Biol Chem.
  
  Volume: 286(47) Pages: 40835-46
- NAID
  120007137356
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- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K,Nakagawa Y, Iwasaki H, Kobayashi K, YatohS, Takahashi A, Sone H, Suzuki H, Yahagi N,Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Macrophage Elovl6deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hep atosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Karasawa T, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  Arterioscler Thromb Vase Biol.
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Karasawa T, Matsuzaka T, Yamada N, Shimano H, et al
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Saito R, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659464
[Journal Article] In hibition of ubiquitin ligase F-box and WD re peat domain-containing 7α (Fbw7α) causes he patosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5(KLF5)/peroxisome proliferator-activatedreceptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, EmaM, Nakagawa Y, Nakakuki M, Saito R,Yahagi N, Iwasaki H, Sone H, Takekoshi K,Yatoh S, Kobayashi K, Takahashi A, SuzukiH, Takahashi S, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c)2011
- Author(s)
  Amemiya-Kudo M, Oka J, Takeuchi Y, Okazaki H, Yamamoto T, Yahagi N, Matsuzaka K, Okazaki S, Osuga J, Yamada N, Murase T, Shimano H
- Journal Title
  
  J Biol Chem
  
  Volume: 286(32) Pages: 27902-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density liporotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Yamada N, Shimano H, et al
- Journal Title
  
  Arterioscle Thromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c)2011
- Author(s)
  Amemiya-Kudo M, Oka J, Takeuchi Y, Okazaki H, Yamamoto T, Yahagi N, Matsuzaka K, Okazaki S, Osuga J, Yamada N, Murase T, Shimano H
- Journal Title
  
  J Biol Chem
  
  Volume: 286(32) Pages: 27902-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice2011
- Author(s)
  Kumadaki S, Matsuzaka T, Yamada N, Shimano H, et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286(47) Pages: 40835-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H
- Journal Title
  
  ArteriosclerThromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Kruppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.2011
- Author(s)
  Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(47)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Macrophage Elov16 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Saito R, Matsuzaka T, Yamada N, Shimano H, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(9) Pages: 1973-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice.2011
- Author(s)
  Karasawa T, Takahashi A, Saito R, Sekiya M,Igarashi M, Iwasaki H, Miyahara S,Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N,S himano H
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(8) Pages: 1788-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659463
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, TeraokaY, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659173
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 1222-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element binding protein-lc by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51 Pages: 1859-1870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51 Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659173
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element-binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51(7) Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 391
  
  Pages: 1222-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem. 285(15)
  
  Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun. 391(2)
  
  Pages: 1222-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res.
  
  Volume: 51 Pages: 1859-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(15) Pages: 11681-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.2010
- Author(s)
  Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 391(2) Pages: 1222-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300234
[Journal Article] Protein kinase Cbeta mediates hepatic induction of sterol regulatory element-binding protein-1c by insulin2010
- Author(s)
  Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res. Feb 23.(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010
- Author(s)
  Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 11681-11691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Elovl6 : a new player in fatty acid metabolism and insulin sensitivity.2009
- Author(s)
  Matsuzaka T, Shimano H
- Journal Title
  
  J Mol Med 87
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice2009
- Author(s)
  Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 492-496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] Elov16 : a new player in fatty acid metabolism and insulin sensitivity2009
- Author(s)
  Matsuzaka T, Shimano H
- Journal Title
  
  J Mol Med 87
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052006
[Journal Article] Elovl6 : a new player in fatty acid metabolism and insulin sensitivity2009
- Author(s)
  Matsuzaka T, Shimano H.
- Journal Title
  
  J Mol Med. 87(4)
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689025
[Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice.2009
- Author(s)
  Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 492-496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390275
[Journal Article] Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets2008
- Author(s)
  Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, Nakagawa Y, Yahagi N, Nakakuki M, Hasty AH, Takeuchi Y, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Sone H, Yamada N
- Journal Title
  
  Diabetes 57(9)
  
  Pages: 2382-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice : a new model for lipotoxicity.2008
- Author(s)
  Ishikawa M, Iwasaki Y, Yatoh S, Kato T, Kumadaki S, Inoue N, Yamamoto T, Matsuzaka T, Nakagawa Y, Yahagi N, Kobayashi K, Takahashi A, Yamada N, Shimano H.
- Journal Title
  
  J Lipid Res. 49(12)
  
  Pages: 2524-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Mouse Elov1-6 promoter is an SREBP target.2008
- Author(s)
  Kumadaki S, Matsuzaka T, Shimano H, et. al.
- Journal Title
  
  Biochem Biophys Res Commun (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance2008
- Author(s)
  Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, Nakagawa Y, Takeuchi Y, Kobayashi K, Takahashi A, Suzuki H, Hasty AH, Toyoshima H, Yamada N, Shimano H
- Journal Title
  
  J Biol Chem. 283(30)
  
  Pages: 21220-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Mouse Elovl-6 promoter is an SREBP target.2008
- Author(s)
  Kumadaki, S・Matsuzaka, T・Shimano, H, et. al.
- Journal Title
  
  Biochem Biophys Res Commun (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18052001
[Journal Article] Mouse Elovl-6 promoter is an SREBP target.2008
- Author(s)
  Kumadaki S, Matsuzaka T, Shimano H, et. al.
- Journal Title
  
  Biochem Biophys Res Commun (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659231
[Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding prpten-lc expression.2007
- Author(s)
  Takeuchi, Y・Nakagawa, Y・Matsuzaka, T・Shimano, H., et. al.
- Journal Title
  
  Biochem Biophys Res Commun 363(2)
  
  Pages: 329-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18052001
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elov16,in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka, T・Shimano, H・Nakagawa, Y. Et al.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-1202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18052001
[Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-lc expression.2007
- Author(s)
  Takeuchi Y, Nakagawa Y, Matsuzaka T, Shimano H., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 363(2)
  
  Pages: 329-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] A transcription factor of lipid synthesis, sterol regulatory element-binding protein(SREBP)-1a causes G(1)cell-cycle arrest after accumulation of cyclin-dependent kinase(cdk)inhibitors.2007
- Author(s)
  Nakakuki M, Shimano H Matsuzaka T, Nakagawa Y, et. al.
- Journal Title
  
  FEBS J. 274(17)
  
  Pages: 4440-4452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659231
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, Sekiya M, Ohashi K, Hasty AH, Nakagawa Y, Takahashi A, Suzuki H, Yatoh S, Sone H, Toyoshima H, Osuga J, Yamada N.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.2007
- Author(s)
  Takeuchi Y, Nakagawa Y, Matsuzaka T, Shimano H., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 363(2)
  
  Pages: 329-35
- NAID
  120007139072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659231
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, Shimano H, Nakagawa Y, et. al.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-1202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659231
[Journal Article] A transcription factor of lipid synthesis, sterol regulatory element-binding protein(SREBP)-la causesG(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors.2007
- Author(s)
  Nakakuki, M・Shimano, H・Matsuzaka, T・Nakagawa, Y, et. al.
- Journal Title
  
  FEBS J. 274(17)
  
  Pages: 4440-4452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18052001
[Journal Article] Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver2007
- Author(s)
  Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N.
- Journal Title
  
  J Biol Chem. 282(16)
  
  Pages: 11687-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] A transcription factor of lipid synthesis, sterol regulatory element-binding protein(SREBP)-la causes G(l) cell-cycle arrest after accumulation of cyclin-dependent kinase(cdk)inhibitors.2007
- Author(s)
  Nakakuki M, Shimano H Matsuzaka T, Nakagawa Y, et. al.
- Journal Title
  
  FEBS J. 274(17)
  
  Pages: 4440-4452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Crucial role of a long-chain fatty acid elongase, Elov16, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, Shimano H, Nakagawa Y, et. al.
- Journal Title
  
  Nat Med. 13(10)
  
  Pages: 1193-1202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Crucial role of long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance2007
- Author(s)
  Matsuzaka T, et. al.
- Journal Title
  
  Nature Medicine 13
  
  Pages: 1193-1202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790610
[Journal Article] SREBP-1-independent regulation of lipogenic gene expression in adipocytes2007
- Author(s)
  Sekiya M, Yahagi N, Matsuzaka T, Takeuchi Y, Nakagawa Y, Takahashi H, Okazaki H, Iizuka Y, Ohashi K, Gotoda T, Ishibashi S, Nagai R, Yamazaki T, Kadowaki T, Yamada N, Osuga J, Shimano H.
- Journal Title
  
  J Lipid Res. 48(7)
  
  Pages: 1581-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390245
[Journal Article] Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.2006
- Author(s)
  Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N.
- Journal Title
  
  Cell Metab. 4(2)
  
  Pages: 143-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390259
[Journal Article] Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol : a potential role in adipocyte lipolysis.2006
- Author(s)
  Okazaki H, Igarashi M, Nishi M, Tajima M, Sekiya M, Okazaki S, Yahagi N, Ohashi K, Tsukamoto K, Amemiya-Kudo M, Matsuzaka T, Shimano H, Yamada N, Aoki J, Morikawa R, Takanezawa Y, Arai H, Nagai R, Kadowaki T, Osuga J, Ishibashi S.
- Journal Title
  
  Diabetes. J55(7)
  
  Pages: 2091-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390259
[Journal Article] Protein Kinase A suppresses SREBP-1c expression via phosphorylation of LXR in the liver.2000
- Author(s)
  Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N.
- Journal Title
  
  J Biol Chem. (Epub ahead of print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390259
[Patent] 生細胞内論理ゲートによるオルガネラの形態操作法2019
- Inventor(s)
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Holder
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-211266
- Filing Date
  2019
- Data Source
  KAKENHI-PLANNED-17H06395
[Patent] 生細胞内論理ゲートによるオルガネラの形態操作法2019
- Inventor(s)
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Holder
  宮本崇史、松坂賢、島野仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-211266
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H04051
[Patent] 高分子化環状ニトロキシドラジカル化合物の経口投与用製剤2012
- Inventor(s)
  長崎幸夫、吉冨徹、尾崎祐樹、ペナパーショパトンピクンラット、島野仁、松坂賢、唐澤直義
- Industrial Property Rights Holder
  筑波大学
- Industrial Property Number
  2012-019975
- Filing Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-21390275
[Patent] 高分子化環状ニトロキシドラジカル化合物の経口投与用製剤2012
- Inventor(s)
  長崎幸夫、吉冨徹、尾崎裕樹、ペナパーショパトンピクンラット、島野二、松坂賢、唐澤直義
- Industrial Property Rights Holder
  筑波大学
- Industrial Property Number
  2012-019975
- Filing Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] SREBP-1aによる脂質合成の制御と食餌誘導性脂肪肝炎の病態2023
- Author(s)
  荒木　雅弥、韓　松伊、大崎　芳典、松坂　賢、矢作　直也、関谷　元博、宮本　崇史、中川　嘉、島野　仁
- Organizer
  第55回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 脂肪酸伸長酵素Elov16の欠損は脂肪肝におけるミトコンドリア異常を改善する2023
- Author(s)
  松坂　賢、林　昭夫、島野　仁
- Organizer
  第65回脂質生化学会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 新規に確立した回腸切除モデルマウスを用いた腸管adaptationの検討2023
- Author(s)
  後藤　悠大、増本　幸二、佐々木　理人、小野　健太郎、松坂　賢、島野　仁
- Organizer
  第60回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 心臓線維芽細胞における脂肪酸伸長酵素Elovl6が圧負荷に伴う心臓リモデリングに及ぼす役割2023
- Author(s)
  横町　羽南、松井　弘樹、須永　浩章、忠木　紗耶香、古川　希、川上　亮、磯　達也、小坂橋　紀通、松坂　賢、島野　仁、倉林　正彦、石井　秀樹、横山　知行
- Organizer
  第70回北関東医学会総会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 短腸症候群モデルとしてのマウス回腸切除術の確立と腸管adaptationや腸管不全関連肝障害の検討2023
- Author(s)
  後藤　悠大、松坂　賢、荒木　雅弥、大野　博、小野　健太郎、佐々木　理人、増本　幸二、島野　仁
- Organizer
  第58回日本臨床分子医学会学術総会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 脂質多様性の制御による神経幹細胞の自己複製能・分化能の制御機構解明2023
- Author(s)
  大野　博、松坂　賢、林　昭夫、島野　仁
- Organizer
  第58回日本臨床分子医学会学術総会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 脂肪肝における脂質分子種の変化とミトコンドリア恒常性の破綻2023
- Author(s)
  松坂賢、島野仁
- Organizer
  第96回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] 脂肪酸伸長酵素Elovl6の欠損は脂肪肝におけるミトコンドリア異常を改善する2023
- Author(s)
  松坂賢、林昭夫、島野仁
- Organizer
  第65回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] アセトアミノフェン誘導性急性腎障害におけるElovl6の病態生理的意義の解明2023
- Author(s)
  杉浦　有香、松井　弘樹、須永　浩章、磯　達也、松坂　賢、島野　仁、倉林　正彦、石井　秀樹、横山　知行
- Organizer
  第70回北関東医学会総会
- Data Source
  KAKENHI-PROJECT-22H00474
[Presentation] 脂肪酸伸長酵Elovl6の欠損は脂肪肝におけるミトコンドリア異常を改善する2022
- Author(s)
  松坂賢、林昭夫、島野仁
- Organizer
  第8回肝臓と糖尿病・代謝研究会
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] Elovl6 as a therapeutic target in NAFLD/NASH2022
- Author(s)
  松坂賢、島野仁
- Organizer
  第65回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] in vivo live imaging による膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢、岡島由佳、宮崎俊、本村香織、富田勉、島野仁
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と生活習慣病2021
- Author(s)
  松坂　賢
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 脂肪酸伸長酵素Elovl6による神経幹細胞の自己複製能制御機構解明2021
- Author(s)
  大野博, 松坂賢, 本村香織, 志村拓哉, 水之江雄平, 宮本崇史, 関谷元博, 中川嘉, 林昭夫, 島野仁
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] メタボリックシンドロームにおける脂質代謝研究の最前線　脂肪酸伸長酵素Elovl6による脂質の質の制御とメタボリックシンドローム2021
- Author(s)
  松坂賢, 島野仁
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] in vivo live imagingによる膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢, 岡島由佳, 宮崎俊, 本村香織, 富田勉, 島野仁
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] in vivo live imaging による膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢、岡島由佳、宮崎俊、本村香織、富田勉、島野仁
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] in vivo live imaging による膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢、岡島由佳、宮崎俊、本村香織、富田勉、島野仁
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] 脂肪酸伸長酵素Elovl6による脂質の質の制御とメタボリックシンドローム2021
- Author(s)
  松坂賢
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03371
[Presentation] in vivo live imaging による膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢、岡島由佳、宮崎俊、本村香織、富田勉、島野仁
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] 脂肪酸伸長酵素Elovl6による脂質の質の制御とメタボリックシンドローム2021
- Author(s)
  松坂賢
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] 心臓のミトコンドリアの品質維持を制御する脂肪酸の探索と病態意義の解析2021
- Author(s)
  松井弘樹, 須永浩章, 忠木沙耶香, 古川希, 磯達也, 松坂賢, 島野仁, 倉林正彦, 横山知行
- Organizer
  第28回日本未病学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] in vivo live imaging による膵ランゲルハンス氏島の血流解析2021
- Author(s)
  松坂賢、岡島由佳、宮崎俊、本村香織、富田勉、島野仁
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と生活習慣病2021
- Author(s)
  松坂　賢
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢, 久芳素子, 小安さおり, 本村香織, 大野博, Rahul Sharma, 武内謙憲, 矢作直也, 宮本崇史, 関谷元博, 中川嘉, 島野仁
- Organizer
  第 63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] セラミドの脂肪酸鎖長によるインスリン感受性制御機構と血中脂質2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第62回日本脂質生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 学際研究で切り拓く脂質とアミノ酸のメタボダイナミズム　質量分析を用いた組織・細胞の脂質メタボロミクスとトランスレーショナル応用2020
- Author(s)
  林昭夫、松坂　賢、島野　仁
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢, 久芳素子, 小安さおり, 本村香織, 大野博, Rahul Sharma, 武内謙憲, 矢作直也, 宮本崇史, 関谷元博, 中川嘉, 島野仁
- Organizer
  第89回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] Identification and Characterization of MicroRNA(s) that Regulates ELOVL62020
- Author(s)
  Nurani Istiqamah, Takashi Matsuzaka, Hitoshi Shimano
- Organizer
  Tsukuba Global Science Week (TGSW) 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] グルココルチコイドによるGR-Bmal/Clock複合体を介した時計遺伝子Nr1d1の抑制性転写制御機構2020
- Author(s)
  村山友樹, 矢作直也, 武内謙憲, 會田雄一, 何敏煕, Mehrazad Saber Zahra, 志鎌明人, 升田紫, 泉田欣彦, 宮本崇史, 関谷元博, 中川嘉, 松坂賢, 大崎芳典, 菅野洋子, 岩崎仁, 鈴木浩明, 川上康, 島野仁
- Organizer
  第89回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] セラミドの脂肪酸分子種によるプロテインホスファターゼ2Aの活性制御機構：脂肪酸伸長酵素Elovl6の重要性とインスリン感受性における意義2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 脂肪酸伸長酵素Elovl6による神経新生の制御機構解明2020
- Author(s)
  大野博, 松坂賢, 本村香織, 志村拓哉, 宮本崇史, 関谷元博, 中川嘉, 島野
- Organizer
  日本臨床分子医学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 腸肝転写因子CREBHはSREBPの活性を制御し、動脈硬化発症を抑制する(会議録)2020
- Author(s)
  中川嘉, 王雨農, 韓松伊, 水之江雄平, 荒木雅弥, 関谷元博, 松坂賢, 島野仁
- Organizer
  第 63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] MicroRNA(s) that Regulates ELOVL62020
- Author(s)
  Nurani Istiqamah, Takashi Matsuzaka, Hitoshi Shimano
- Organizer
  Tsukuba Global Science Week (TGSW) 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 学際研究で切り拓く脂質とアミノ酸のメタボダイナミズム　質量分析を用いた組織・細胞の脂質メタボロミクスとトランスレーショナル応用2020
- Author(s)
  林昭夫, 松坂賢, 島野仁
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 血中脂質研究の今　セラミドの脂肪酸鎖長によるインスリン感受性制御機構と血中脂質2020
- Author(s)
  松坂賢, 島野仁
- Organizer
  脂質生化学研究
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 脂肪酸伸長酵素Elovl6は肝臓においてセラミドの脂肪酸鎖長とインスリン感受性を制御する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、大野博、島野　仁
- Organizer
  第14回スフィンゴテラピー研究会
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 小腸切除マウスの肝臓における脂質代謝関連遺伝子発現の検討2020
- Author(s)
  小野健太郎, 佐々木理人, 松坂賢, 島野仁, 増本幸二
- Organizer
  第35回日本臨床栄養代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] セラミドの脂肪酸鎖長によるインスリン感受性制御機構と血中脂質2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第62回日本脂質生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] セラミドの脂肪酸分子種によるプロテインホスファターゼ2Aの活性制御機構：脂肪酸伸長酵素Elovl6の重要性とインスリン感受性における意義2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 小腸切除マウスの肝臓における脂質代謝関連遺伝子発現の検討2020
- Author(s)
  小野健太郎、佐々木理人、松坂賢、島野　仁、増本幸二
- Organizer
  第35回日本臨床栄養代謝学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] セラミドの脂肪酸分子種によるプロテインホスファターゼ2Aの活性制御機構：脂肪酸伸長酵素Elovl6の重要性とインスリン感受性における意義2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21643
[Presentation] 肝臓特異的Elovl6欠損マウスの肝臓ではC18-ceramideが減少することによりインスリン感受性が亢進する2020
- Author(s)
  松坂賢、久芳素子、小安さおり、本村香織、大野博、Sharma R、武内謙憲、矢作直也、宮本崇史、関谷元博、中川嘉、島野　仁
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] ホスファターゼで解き明かす生理と病態のメカニズム　セラミドの脂肪酸分子種によるプロテインホスファターゼ2Aの活性制御機構　脂肪酸伸長酵素Elovl6の重要性とインスリン感受性における意義2020
- Author(s)
  松坂賢, 島野仁
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 転写因子SREBP-1aによる腸管内脂質制御が腸管内部構造に与える影響の検討2020
- Author(s)
  荒木雅弥、中川嘉、韓松伊、水之江雄平、王農雨、松坂賢、関谷元博、矢作直也、島野　仁
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 学際研究で切り拓く脂質とアミノ酸のメタボダイナミズム　脂肪酸の量と質とセンシングの視点からみた脂質多様性とメタボダイナミズム2020
- Author(s)
  島野　仁、松坂　賢、関谷元博、宮本崇史
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] セラミドの脂肪酸鎖長によるインスリン感受性制御機構と血中脂質2020
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第62回日本脂質生化学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] Elucidation of Apoa1 Gene Regulatory Mechanism Through Searching Causal Single-Nucleotide Variants2020
- Author(s)
  Aita Y, Yahagi N, Takeuchi Y, Ho MH, Saber ZM, Huyan Y, Murayama Y, Shikama A, Masuda Y, Izumida Y, Sekiya M, Nakagawa Y, Matsuzaka T, Kawakami Y, Shimano H
- Organizer
  American Heart Association Scientific Sessions 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] 学際研究で切り拓く脂質とアミノ酸のメタボダイナミズム　脂肪酸の量と質とセンシングの視点からみた脂質多様性とメタボダイナミズム2020
- Author(s)
  島野仁, 松坂賢, 関谷元博, 宮本崇史
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] Causal SNV探索を通じたApoA1遺伝子の新たな発現調節機構の解明2020
- Author(s)
  曾田雄一、矢作直也、武内謙憲、何敏熙、Zahra MS、呼延宜人、村山友樹、志鎌明人、升田紫、泉田欣彦、関谷元博、中川嘉、松坂賢、川上康、島野　仁
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] Octacosanol prevents HFD-induced obesity by activating energy expenditure and thermogenesis in brown and beige fats2019
- Author(s)
  Sharma R, Matsuzaka T, Kaushik MK, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Shimano H.
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] Hepatocyte-specific deletion of Elovl6 enhances hepatic insulin sensitivity through suppression of C18:0-ceramide production2019
- Author(s)
  Takashi Matsuzaka, Kaori Motomura, Hiroshi Ohno, Rahul Sharma, Takuya Shimura, Yuta Yamamoto, Sundaram Arulmozhiraja, Takafumi Miyamoto, Motohiro Sekiya, Yoshimi Nakagawa, Akio Hayashi, Hiroaki Tokiwa, Hitoshi Shimano
- Organizer
  60th International Conference on the Bioscience of Lipids (ICBL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] CREBH regulates ChREBP-mediated hepatic fructose metabolism2019
- Author(s)
  Yunong Wang, Yoshimi Nakagawa, Song-Iee Han, Kae Kumagai, Yuhei Mizunoe, Masaya Araki, Motohiro Sekiya, Takashi Matsuzaka, Hitoshi Shimano
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] 膵β細胞の増殖を誘導する脂肪酸の探索とその分子機構の解析2019
- Author(s)
  本村香織、松坂賢、大野博、宮本崇史、関谷元博、中川嘉、島野仁
- Organizer
  第56回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19724
[Presentation] 脂肪酸伸長酵素Elovl6による肝臓インスリン感受性制御機構の解析2019
- Author(s)
  松坂　賢、林　昭夫、島野　仁
- Organizer
  第61回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と組織内蓄積脂肪2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第40回日本臨床栄養学会総会・第39回日本臨床栄養協会総会　第16回大連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19724
[Presentation] 脂肪酸の質的変化による脂質代謝、エネルギー代謝2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 転写因子CREBHの未成熟型・成熟型による動脈硬化形成に対する二重支配の分子メカニズム2018
- Author(s)
  中川嘉、韓松伊、大石麻代、王雨農、関谷元博、松坂賢、島野仁
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と組織内蓄積脂肪2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第40回日本臨床栄養学会総会・第39回日本臨床栄養協会総会　第16回大連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04051
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と組織内蓄積脂肪2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第40回日本臨床栄養学会総会・第39回日本臨床栄養協会総会　第16回大連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 脂肪酸の質的変化による脂質代謝、エネルギー代謝2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第61回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19724
[Presentation] 脂肪酸の質的変化による脂質代謝、エネルギー代謝2018
- Author(s)
  松坂賢、島野仁
- Organizer
  第61回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03189
[Presentation] 脂肪酸伸長酵素Elovl6の成長板の発達における役割の検討2017
- Author(s)
  嶋田昌子、菊地愛美、松坂賢、中川嘉、島野仁
- Organizer
  第20回日本病態栄養学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2017-01-13
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と異所性脂肪2017
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第38回日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 生活習慣病における脂肪酸組成制御の重要性と脂肪酸伸長酵素Elovl6の役割2017
- Author(s)
  松坂　賢、島野　仁
- Organizer
  日本内分泌学会第35回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] CREB3L3欠損による動脈硬化発症の分子メカニズム2017
- Author(s)
  中川　嘉、関谷　元博、松坂　賢、島野　仁
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PLANNED-17H06395
[Presentation] A new aspect of organ lipids in various diseases, lessons from Elovl6.2017
- Author(s)
  Shimano H, Matsuzaka T.
- Organizer
  The 19th Takeda Science Foundation Symposium on Bioscience “Chronic Inflammation～Initiation, Progression and Resolution
- Place of Presentation
  Takeda Pharmaceutical Company Limited（大阪府中央区）
- Year and Date
  2017-01-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 生活習慣病における脂肪酸組成制御の重要性と脂肪酸伸長酵素Elovl6の役割2017
- Author(s)
  松坂　賢、島野　仁
- Organizer
  日本内分泌学会第35回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 生活習慣病における脂肪酸組成制御の重要性と脂肪酸伸長酵素Elovl6の役割2017
- Author(s)
  松坂賢、島野仁
- Organizer
  第20回日本病態栄養学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2017-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] CREB3L3欠損による動脈硬化発症の分子メカニズム2017
- Author(s)
  中川　嘉、関谷　元博、松坂　　賢、島野　　仁
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-16H03253
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸の質の制御と異所性脂肪2017
- Author(s)
  松坂　賢、島野　仁
- Organizer
  第38回日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪酸伸長酵素Elovl6の高次脳機能における役割2016
- Author(s)
  大野博、松坂賢、島野仁
- Organizer
  第53回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] he role of fatty acid elongase in brown adipose tissue2016
- Author(s)
  Rahul Sharma、松坂賢、本村香織、Hui Zhao、大野博、武内謙憲、矢作直也、関谷元博、中川　嘉、村谷匡史、島野仁
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン（東京都江東区）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] Crucial role of Elovl6 in chondrocyte growth and differentiation during growth plate development in mice.2016
- Author(s)
  Shimada M, Kikuchi M, Matsuzaka T, Nakagawa Y, and Shimano H.
- Organizer
  ASBMR Annual Meeting
- Place of Presentation
  Atlanta GA, USA
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスにおけるショ糖嗜好性亢進2016
- Author(s)
  千葉恵、松坂賢、煙山紀子、籐麻里子、大野博、関谷元博、中川嘉、矢作直也、島野仁
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン（東京都江東区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 脂肪酸伸長酵素Elovl6 の欠損はdb/dbマウスの2型糖尿病の発症・進展を抑制する2016
- Author(s)
  趙会、松坂賢、中野雄太、唐寧、鈴木真璃衣、武内謙憲、岩崎仁、小林和人、矢藤繁、鈴木浩明、矢作直也、中川嘉、山田信博、島野仁
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 脂肪酸伸長酵素 Elovl6 の骨・成長板発達異常の背景となる分子機序の検討2016
- Author(s)
  菊地愛美、松坂賢、石井清朗、中川嘉、島野仁、嶋田昌子
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] Elovl6 の欠損は胆石形成食負荷 LDL 受容体二重欠損マウスにおける脂肪性肝炎の発症を抑制するが，胆石形成を促進する2016
- Author(s)
  久芳素子、松坂賢、大野博、中川嘉、矢作直也、島野仁
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 脂肪酸身長酵素Elovl6の骨・成長板発達異常の背景となる分子機序の検討2016
- Author(s)
  菊地愛美、嶋田昌子、松坂賢、中川嘉、島野仁
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸組成制御と生活習慣病2016
- Author(s)
  松坂賢、島野仁
- Organizer
  第97回日本栄養·食糧学会関東支部大会シンポジウム
- Place of Presentation
  東京大学農学部弥生キャンパス（東京）
- Year and Date
  2016-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 脂肪酸伸長酵素Elovl6の骨・軟骨細胞における役割の検討2015
- Author(s)
  菊池愛美、嶋田昌子、松坂賢、石井清明、中川嘉、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 栄養飢餓により活性化する転写因子とCREB3L3は肥満及び糖代謝を改善する2015
- Author(s)
  佐藤　葵、中川　嘉、松坂　賢、島野　仁
- Organizer
  第27回分子糖尿病学シンポジウム
- Place of Presentation
  丸ビルホール（東京）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脳における脂肪酸伸長酵素Elovl6の役割2015
- Author(s)
  大野博、松坂賢、吉田恵里子、伏見友希、所司慶太、中川嘉、矢作直也、山田信博、島野　仁
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの糖尿病の発症・進展を抑制する2015
- Author(s)
  松坂賢、中野雄太、趙会、唐寧、鈴木真璃衣、大野博、中川嘉、矢作直也、山田信博、島野　仁
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] The role of Elovl6 in bone and cartilage2015
- Author(s)
  Manami Kikuchi, Masako Shimada, Takashi Matsuzaka, Kiyoaki Ishii, Yoshimi Nakagawa, Hitoshi Shimano
- Organizer
  Tsukuba Global Science Week
- Place of Presentation
  Tsukuba, Ibaraki
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの2型糖尿病の発症・進展を抑制する2015
- Author(s)
  趙会、松坂　賢、中野雄太、Nie Tang、鈴木真璃衣、武内謙憲、岩崎　仁、小林和人、矢藤　繁、鈴木浩明、矢作直也、中川　嘉、山田信博、島野　仁
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子CREB3L3による絶食時エネルギー代謝調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、大崎　芳典、松坂　賢、山田　信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ(京都府京都市)
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 脂肪酸伸長酵素Elovl6 の欠損はdb/dbマウスの2型糖尿病の発症・進展を抑制する2015
- Author(s)
  趙会、松坂賢、中野雄太、唐寧、鈴木真璃衣、武内謙憲、岩崎仁、小林和人、矢藤繁、鈴木浩明、矢作直也、中川嘉、山田信博、島野仁
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 脂肪酸身長酵素Elovl6の骨・軟骨細胞における役割の検討2015
- Author(s)
  菊地愛美、嶋田昌子、松坂賢、石井清明、中川嘉、島野仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6の骨・軟骨細胞における役割の検討2015
- Author(s)
  菊地愛美、嶋田昌子、松坂賢、石井清朗、中川嘉、島野仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] 転写因子CREB3L3による絶食時エネルギー代謝調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、大崎芳典、松坂　賢、山田信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] Creb313の動脈硬化形成における役割2015
- Author(s)
  柳下友花、中川嘉、奥田佳菜子、八木豊美、佐藤葵、及川総香、松坂賢、岩崎仁、小林和人、矢作直也、矢藤繁、鈴木浩明、山田信博、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脂肪組織におけるin vivo Ad-luc法によるfatty acid synthaseのプロモーター解析2015
- Author(s)
  西　真貴子、矢作直也、武内謙憲、志鎌明人、戸谷直樹、大屋友華里、朴　賢英、曾田雄一、沢田義一、松坂　賢、中川　嘉、升田　紫、泉田欣彦、飯塚陽子、山田信博、門脇　孝、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] Leptin遺伝子発現調節機構のin vivo Ad-luc解析2015
- Author(s)
  戸谷直樹、矢作直也、武内謙憲、西　真貴子、沢田義一、朴　賢英、曾田雄一、大屋友華里、志鎌明人、松坂賢、中川　嘉、升田　紫、久保田みどり、泉田欣彦、門脇　孝、山田信博、島野　仁
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] がん抑制遺伝子RBとSREBP1の発がん制御における協調的作用2015
- Author(s)
  村中勇人、多田秀明、林　昭夫、南　圭一、丹下正一朗、北嶋俊輔、鈴木健之、松坂　賢、島野　仁、高橋智聡
- Organizer
  第57回日本脂質生化学会
- Place of Presentation
  一橋大学千代田キャンパス（東京）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] Enhanced high sucrose diet preference in Elovl6 deficient mice2015
- Author(s)
  Mariko Toh, Noriko Suzuki-kemuriyama, Yuki Fushimi, Eriko Yoshida, Hiroshi Ohno, Junko Kato, Takashi Matsuzaka, Nobuhiro Yamada, Kaoruko Iida, Hitoshi Shimano.
- Organizer
  12th Asian Congress of Nutrition (12th ACN)
- Place of Presentation
  Pacifico Yokohama, Japan.
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] Comparison of the effects of EPA and DHA on the development of NASH2015
- Author(s)
  Noriko Kemuriyama, Takashi Matsuzaka, Takeuchi Yoshinori, Nakagawa Yoshimi, Yahagi Naoya, Yamada Nobuhiro, Shimano Hitoshi.
- Organizer
  12th Asian Congress of Nutrition (12th ACN)
- Place of Presentation
  Pacifico Yokohama, Japan.
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03093
[Presentation] トン食摂食時のエネルギー代謝に関わる新たな遺伝子発現調節機構2015
- Author(s)
  中川　嘉、佐藤　葵、松坂　賢、山田信博、島野　仁
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 転写因子Creb313の動脈硬化進展に及ぼす影響2015
- Author(s)
  柳下友花、中川　嘉、佐藤　葵、大崎芳典、松坂　賢、山田信博、島野　仁
- Organizer
  第52回日本臨床分子医学会学術集会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-15H02541
[Presentation] 脳神経系の形成と発達における脂肪酸伸長酵素Elovl6の役割2014
- Author(s)
  吉田恵里子、松坂賢、大野博、伏見友希、所司慶太、島野仁
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 転写因子CREBH による動脈硬化発症進展における役割2014
- Author(s)
  中川嘉、奥田佳菜子、八木豊美、折原佳奈、佐藤葵、及川総香、松坂賢、嶋田昌子、岩崎仁、小林和人、矢藤繁、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学(北海道・札幌)
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの糖尿病の発症・進展を抑制する2014
- Author(s)
  松坂賢、中野雄太、趙会、唐寧、鈴木真璃衣、中川嘉、嶋田昌子、武内謙憲、岩崎仁、小林和人、高橋昭光、矢藤繁、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] Deletion of Elovl6 ameliorates hyperglycemia in db/db mice2014
- Author(s)
  Takashi Matsuzaka, Yuta Nakano, Zhao Hui, Marii Suzuki, Tang Nie, Yoshimi Nakagawa, Naoya Yahagi, Nobuhiro Yamada, Hitoshi Shimano
- Organizer
  9th Metabolic Syndrome,Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 転写因子CREBHの動脈硬化発症進展における役割2014
- Author(s)
  中川　嘉、奥田　佳菜子、八木　豊美、折原　佳奈、佐藤　葵、及川　総香、松坂　賢、嶋田　昌子、岩崎　仁、小林　和人、高橋　昭光、矢藤　繁、矢作　直也、鈴木　浩明、山田　信博、島野　仁
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25282214
[Presentation] 脂肪酸伸長酵素Elovl6の欠損はdb/dbマウスの2型糖尿病の発症・進展を抑制する2014
- Author(s)
  松坂賢、中野雄太、趙会、唐寧、鈴木真璃衣、中川嘉、嶋田昌子、武内謙憲、岩崎仁、小林和人、矢藤繁、高橋昭光、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 高次脳機能における脂肪酸伸長酵素Elovl6の役割2014
- Author(s)
  大野博、松坂賢、吉田恵里子、伏見友希、所司慶太、島野仁
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 糖・脂質代謝調節におけるCREBH-PPARa相互作用の解明2013
- Author(s)
  中川嘉、佐藤葵、松坂賢、岩崎仁、小林和人、矢藤繁、嶋田昌子、矢作直也、山田信博、鈴木浩明、島野仁
- Place of Presentation
  熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] Elovl6 promotesnonalcoholic steatohepatitis in mice andhumans2012
- Author(s)
  Takashi Matsuzaka, Tang Nie, NorikoSuzuki-Kemuriyama, Motoko Kuba, YoshimiNakagawa, Kiyoaki Ishii, Masako Shimada,Kazuto Kobayashi, Shigeru Yatoh, AkimitsuTakahashi, Hirohito Sone, Naoya Yahagi,Hiroaki Suzuki, Makoto Nakamuta, NobuhiroYamada, Hitoshi Shim
- Organizer
  9th IDF-WPR Congress and 4th AASDScientific Meeting
- Place of Presentation
  国立京都国際会館, 京都
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] Deletion of Elovl6 protects against the failure of pancreatic beta-cell mass and function in db/db mice.2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, Nie Tang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, Keita Shoshi, Tomotaka Yokoo, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Hitoshi Iwasaki, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Naoya Yahagi, Hiroaki Suzuki, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] "PEGylated and quaternized polyamine nanogel", a brand-new bile acid sequestrant, ameliorates lipoprotein profiles and reduces atherosclerosis in low-density-lipoprotein receptor deficient and apolipoprotein E deficient mice2012
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第76回日本循環器病学会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、齋藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橘昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] Deletion of Elovl6 protects against the failure of pancreatic beta-cell mass and function in db/db mice.2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, Nie Tang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, Keita Shoshi, Tomotaka Yokoo, Yoshimi NaKagawa, Kiyoaki Ishii, Masako Shimada, Hitoshi Iwasaki, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Naoya Yahagi, Hiroaki Suzuki, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] "PEGylated and quatemized polyamine nanogel", a brand-new bile acid sequestrant, ameliorates lipoprotein profiles and reduces atherosclerosis in low-density-lipoprotein receptor deficient and apolipoprotein E deficient mice2012
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第76回日本循環器病学会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、齋藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橋昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、齋藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橋昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23659464
[Presentation] Deletion of Elovl6 protects against thefailure of pancreatic beta-cell mass andfunction in db/db mice2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, NieTang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, KeitaShoshi, Tomotaka Yokoo, Yoshimi Nakagawa,Kiyoaki Ishii, Masako Shimada, HitoshiIwasaki, Kazuto Kobayashi, Shigeru Yatoh,Akimitsu Takahashi, Naoya Yahagi, Hi
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡、福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割2012
- Author(s)
  松坂賢、斎藤亮、唐澤直義、松森理恵、煙山紀子、中川嘉、石井清朗、岩崎仁、小林和人、矢藤繁、高橘昭光、曽根博仁、鈴木浩明、矢作直也、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] Elovl6 promotes nonalcoholic steatohepatitis in mice and humans.2012
- Author(s)
  Takashi Matsuzaka. Tang Nie, Noriko Suzuki-Kemuriyama, Motoko Kuba, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Hirohito Sone, Naoya Yahagi, Hiroaki Suzuki, Makoto Nakamuta, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] Elov16 promotes nonalcoholic steatohepatitis in mice and humane.2012
- Author(s)
  Takashi Matauzaka, Tang Nie, Noriko Suzuki-Kemuriyama, Motoko Kuba, Yoshimi Nakagawa, Kiyoaki Ishii, Masako Shimada, Kazuto Kobayashi, Shigeru Yatoh, Akimitsu Takahashi, Hirohito Sone, Naoya Yahagi, Hiroaki Suzuki, Makoto Nakamuta, Nobuhiro Yamada, Hitoshi Shimano.
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] Elovl6 promotesnonalcoholic steatohepatitis in mice andhumans2012
- Author(s)
  Takashi Matsuzaka, Tang Nie, NorikoSuzuki-Kemuriyama, Motoko Kuba, YoshimiNakagawa, Kiyoaki Ishii, Masako Shimada,Kazuto Kobayashi, Shigeru Yatoh, AkimitsuTakahashi, Hirohito Sone, Naoya Yahagi,Hiroaki Suzuki, Makoto Nakamuta, NobuhiroYamada, Hitoshi Shim
- Organizer
  9th IDF-WPR Congress and 4th AASDScientific Meeting
- Place of Presentation
  国立京都国際会館, 京都
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-23659464
[Presentation] Deletion of Elovl6 protects against thefailure of pancreatic beta-cell mass andfunction in db/db mice2012
- Author(s)
  Yuta Nakano, Takashi Matsuzaka, NieTang, Marii Suzuki, Noriko Suzuki-Kemuriyama, Motoko Kuba, KeitaShoshi, Tomotaka Yokoo, Yoshimi Nakagawa,Kiyoaki Ishii, Masako Shimada, HitoshiIwasaki, Kazuto Kobayashi, Shigeru Yatoh,Akimitsu Takahashi, Naoya Yahagi, Hi
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡、福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23659464
[Presentation] "PEGylated and quaternized polyamine nanogel", a brand-new bile acid sequestrant, ameliorates lipoprotein profiles and reduces atherosclerosis in low-density-lipoprotein receptor deficient and apolipoprotein E deficient mice2012
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第76回日本循環器病学会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] "PEGylated and quaternized polyamine nanogel" a novel bile salt seque stering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第43回日本動脈硬化学会学術集会
- Place of Presentation
  ロイトン札幌(札幌市)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] A novel bile salt sequestering agent PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] PEGylatedand quaternized polyamine nanogel a novelbile salt sequestering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第43 回日本動脈硬化学会学術集会
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] A novel bile salt sequestering agent_"PEGylated and quaternized polya mine nanogel" reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第84回米国心臓協会学術集会(AHA Scientific Sessions 2011)
- Place of Presentation
  アメリカ(フロリダ)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] A novelbile salt sequestering agent_"PEGylated andquaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第84回米国心臓協会学術集会
- Place of Presentation
  AHA Scientific Sessions2011
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] A novel bile salt sequestering agent PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] A novel bile salt sequestering agent_"PEGylated and quaternized polyamine nanogel" reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第84回米国心臓協会学術集会(AHA Scientific Sessions 2011)
- Place of Presentation
  アメリカ(フロリダ)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] A novel bile salt sequestering agent_PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第84回米国心臓協会学術集会(AHA Scientific Sessions2011)
- Place of Presentation
  Orange Country Convention Center, Orlando, Florida,USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] PEGylated and quaternized polyaminena nogel a novel bile salt sequestering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第43回日本動脈硬化学会学術集会
- Place of Presentation
  ロイトン札幌、札幌
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] A novel bile salt sequestering agent PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] Anovel bile salt sequestering agent PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] "PEGylated and quaternized polyamine nanogel" a novel bile salt sequestering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第43回日本動脈硬化学会学術集会
- Place of Presentation
  ロイトン札幌(札幌市)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] A novel bile salt sequestering agent PEGylated and quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第34回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] PEGylatedand quaternized polyamine nanogel a novel bile salt sequestering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第43回日本動脈硬化学会学術集会
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] A novel bile salt sequestering agent "PEGylated and quaternized polyamine nanogel" reduces YLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第84回米国心臓協会学術集会(AHA Scientific Sessions 2011)
- Place of Presentation
  アメリカ(フロリダ)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-23659463
[Presentation] A novel bile salt sequestering agent_PEGylated and quaternized polyamine nanogel reduces VLDLand LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第84回米国心臓協会学術集会(AHA Scientific Sessions 2011)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] A novel bile salt sequestering agent PEGylated a nd quaternized polyamine nanogel reduces VLDL and LDL cholesterol, raises HDL cholesterol, and prevents atherosclerosis in mice2011
- Author(s)
  Haruna Shinozaki, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al
- Organizer
  第34回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21390275
[Presentation] "PEGylated and quaternized polyamine nanogel" a novel bile salt sequestering agent, ameliorates dyslipidmia through reduction of VLDL and LDL cholesterol, and induction of HDL cholesterol2011
- Author(s)
  Rie Matsumori, Takashi Matsuzaka, Yukio Nagasaki, Hitoshi Shimano, et al.
- Organizer
  第43回日本動脈硬化学会学術集会
- Place of Presentation
  ロイトン札幌(札幌市)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] 肥満病態モデルマウスにおける糖・脂質代謝制御因子CREBH の影響2010
- Author(s)
  藤本ゆり,中川嘉,徳重直子,三上素樹,新行内晶子,木綿梢里,佐藤葵,松坂賢,石井清朗,山田信博,島野仁
- Organizer
  BMB2010 第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] Nutritional regulation and physiological role of ELOVL family member 5(Elovl5)2010
- Author(s)
  Takashi Matsuzaka, Saori Koyasu, Yoshimi Nakagawa, Tomotaka Yokoo, Nobuhiro Yamada, Hitoshi Shimano
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] 生活習慣病における脂質代謝制御因子CREBH の機能解析2010
- Author(s)
  徳重直子,中川嘉,三上素樹,新行内晶子,藤本ゆり,木綿梢里,佐藤葵,松坂賢,石井清朗、山田信博,島野仁
- Organizer
  BMB2010第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] The liver-enriched transcriptionfactor CREBH is nutritionally regulated and activated by fatty acids and PPARa in vitro and in vivo.2010
- Author(s)
  三上素樹,中川嘉,徳重直子,新行内晶子,木綿梢里,藤本ゆり,佐藤葵,松坂賢,石井清朗,山田信博,島野仁
- Organizer
  BMB2010第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22300234
[Presentation] 糖尿病における脂肪酸組成コントロールの重要性と長鎖脂肪酸伸長酵素Elovl6の役割2009
- Author(s)
  松坂賢、山田信博、島野仁
- Organizer
  第52回日本糖尿病学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] 非アルコール性脂肪性肝炎の発症・進展における脂肪酸伸長酵素Elovl6の役割2009
- Author(s)
  松坂賢、島野仁、渥美綾香、山田信博
- Organizer
  第82回日本内分泌学会学術集会
- Place of Presentation
  群馬県民会館
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21689025
[Presentation] 骨格筋特異的に発現するTFE3 の解析2008
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 松坂賢, 小林和人, 矢藤繁, 高橋昭光, 鈴木浩明, 山田信博
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] 骨格筋におけるTFE3の機能解析2008
- Author(s)
  岩崎仁, 島野仁, 中川嘉, 松坂賢, 石井清朗, 小林和人, 矢藤繁, 高橋昭光, 鈴木浩明, 山田信博
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] TFE3による脂肪細胞の分化への影響2007
- Author(s)
  中川嘉、島野仁、岩崎仁、松坂賢、高橋昭光、鈴木浩明、山田信博
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19390245
[Presentation] 脂肪酸伸長酵素Fatty acyl-CoA elongase (FACE)の生体内における機能ならび病態への関与2007
- Author(s)
  松坂賢・島野仁・山田信博, 他
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18790610
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスはショ糖嗜好性が亢進する
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6の欠損は高コレステロール食誘導性脂肪肝を改善する
- Author(s)
  久芳素子、松坂賢、煙山紀子、唐ネ、大野博、中川嘉、矢藤繁、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 膵ベータ細胞における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  唐ネ、松坂賢、鈴木真璃衣、中野雄太、煙山（鈴木）紀子、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 非アルコール性脂肪性肝炎における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂賢、渥美綾香、唐寧、煙山紀子、久芳素子、中川嘉、嶋田昌子、小林和人、矢藤繁、高橋昭光、曽根博仁、矢作直也、鈴木浩明、中牟田誠、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 膵ベータ細胞における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  唐ネ、松坂賢、鈴木真璃衣、中野雄太、煙山（鈴木）紀子、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂　賢
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23659464
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスはショ糖嗜好性が亢進する
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスの摂食行動解析
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 脂肪酸伸長酵素Elovl6の欠損は高コレステロール食誘導性脂肪肝を改善する
- Author(s)
  久芳素子、松坂賢、煙山紀子、唐ネ、大野博、中川嘉、矢藤繁、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] Elovl6 promotes nonalcoholic steatohepatitis in mice and humans.
- Author(s)
  Matsuzaka T
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting.
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23659464
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスの摂食行動解析
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスの摂食行動解析
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 非アルコール性脂肪性肝炎における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂賢、渥美綾香、唐寧、煙山紀子、久芳素子、中川嘉、嶋田昌子、小林和人、矢藤繁、高橋昭光、曽根博仁、矢作直也、鈴木浩明、中牟田誠、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 脂肪酸伸長酵素Elovl6の骨軟骨細胞における役割の検討
- Author(s)
  菊地愛美、嶋田昌子、松坂賢、石井清明、中川嘉、島野仁
- Organizer
  第58回　日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-26560393
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸組成制御と生活習慣病
- Author(s)
  松坂　賢、島野　仁
- Organizer
  日本内分泌学会　第32回内分泌代謝学サマーセミナー
- Place of Presentation
  富士レークホテル
- Year and Date
  2014-07-10 – 2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-25670430
[Presentation] 脂肪酸伸長酵素Elovl6欠損マウスはショ糖嗜好性が亢進する
- Author(s)
  煙山（鈴木）紀子、松坂賢、所司慶太、加藤淳子、唐ネ、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] Elovl6 promotes nonalcoholic steatohepatitis in mice and humans.
- Author(s)
  Takashi Matsuzaka
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24659441
[Presentation] 非アルコール性脂肪性肝炎における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂賢、渥美綾香、唐寧、煙山紀子、久芳素子、中川嘉、嶋田昌子、小林和人、矢藤繁、高橋昭光、曽根博仁、矢作直也、鈴木浩明、中牟田誠、山田信博、島野仁
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6の欠損は高コレステロール食誘導性脂肪肝を改善する
- Author(s)
  久芳素子、松坂賢、煙山紀子、唐ネ、大野博、中川嘉、矢藤繁、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-24390230
[Presentation] 脂肪酸伸長酵素Elovl6による脂肪酸組成制御と生活習慣病
- Author(s)
  松坂賢、島野仁
- Organizer
  日本内分泌学会　第32回内分泌代謝学サマーセミナー
- Place of Presentation
  富士レークホテル
- Year and Date
  2014-07-10 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] 膵ベータ細胞における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  唐ネ、松坂賢、鈴木真璃衣、中野雄太、煙山（鈴木）紀子、久芳素子、岩崎仁、小林和人、矢藤繁、石井清明、中川嘉、嶋田昌子、矢作直也、鈴木浩明、山田信博、島野仁
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24680072
[Presentation] マクロファージ泡沫化および動脈硬化における脂肪酸伸長酵素Elovl6の役割
- Author(s)
  松坂　賢
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659441

1. SHIMANO Hitoshi (20251241)

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# of Collaborated Products: 176 results
2. NAKAGAWA Yoshimi (80361351)

# of Collaborated Projects: 16 results

# of Collaborated Products: 100 results
3. ISHII Kiyoaki (80419150)

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4. TAKAHASHI Akimitsu (70344893)

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6. NAOYA Yahagi (60420246)

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7. Kandori Shuya (50707825)

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10. YATOH Shigeru (50451703)

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11. KATAGIRI Hideki (00344664)

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12. Shimada Masako (30637369)

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27. TOUME Kazufumi

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28. Kohno Susumu

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29. USUI Fumitake

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30. IZUMIDA Yoshihiko

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31. FUKUDA Kuniaki

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32. 高橋照光

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37. 三浦征

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38. 鈴木英雄

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39. 正田純一

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40. 岡田浩介

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42. 佐藤隆一郎

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44. 小西守周

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48. 高橋将文

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50. 唐澤直義

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52. 児玉暁

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59. 倉林正彦

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Matsuzaka Takashi 松坂 賢

MATSUZAKA Takashi 松坂 賢

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脂肪酸鎖長制御に基づく代謝性肝疾患の発症予防・治療機序の解明Principal Investigator

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骨格筋の運動適応における脂肪酸の質の意義の解明Principal Investigator

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Elucidation of the novel regulatory mechanism of mitochondrial function by fatty acids and its application to prevention and treatment of lifestyle-related diseasesPrincipal Investigator

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Elucidation of the significance of the quality of fatty acids in the bladder cancerPrincipal Investigator

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Elucidation of the novel mechanism of the fatty acid-induced pancreatic beta-cell proliferation and its application to diabetes treatmentPrincipal Investigator

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Elucidation of the molecular mechanism of preventing diabetes onset by the regulation of fatty acid composition and its application for the prevention and treatment of type 2 diabetesPrincipal Investigator

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Matsuzaka Takashi 松坂賢

MATSUZAKA Takashi 松坂賢