PARK HEEWON ＰＡＲＫＨＥＥＷＯＮ

… Alternative Names

Park Heewon PARK HEEWON

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Researcher Number	70756642
Other IDs
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, M&Dデータ科学センター, 非常勤講師 2022: 東京医科歯科大学, M&Dデータ科学センター, 非常勤講師 2020 – 2021: 東京医科歯科大学, M&Dデータ科学センター, 教授 2019: 広島大学, 情報科学部, 准教授 2017 – 2018: 山口大学, 国際総合科学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related Except Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Biological Sciences / Complex systems
Keywords	Principal Investigator Statistical modeling / 抗がん剤耐性メカニズム / Explainable AI / Gene regulatory network / Personalized medicine / スパース主成分 / genetic relationship / GWAS / ネットワーク解析 / Sample-specific analysis … More / 説明可能なAI / 抗がん剤耐性 / 統計モデリング / 個別化医療 / 遺伝子ネットワーク … More Except Principal Investigator がん / ネットワーク推定 / シングルセルデータ解析 / ネットワーク解析 / ネットワーク / 説明可能AI / 一細胞計測 / ゲノム・エピゲノム解析 / 加齢 / クローン進化 / 体細胞モザイク / 人工知能 / バイオインフォマティクス / 統計的モデリング / システム生物学 Less

Understanding of clonal evolution in cancer and normal tissues
- Principal Investigator
  
  小川誠司
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
説明可能AIによる１細胞計測大規模ネットワークデータからの知識発見技術の開発
- Principal Investigator
  
  山口類
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Aichi Cancer Center Research Institute
Develop explainable AI strategies for uncovering molecular mechanism behind disease based on gene network analysisPrincipal Investigator
- Principal Investigator
  
  PARK HEEWON
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tokyo Medical and Dental University
Statistical Modeling for Evidence based Personalized MedicinePrincipal Investigator
- Principal Investigator
  
  Park Heewon
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Tokyo Medical and Dental University
  Hiroshima University
Neodimensional exploration for cancer systems by supercomputing and innovative information technology
- Principal Investigator
  
  MIYANO SATORU
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation

[Journal Article] Differential Gene Regulatory Network Analysis between Azacitidine-Sensitive and -Resistant Cell Lines2024
- Author(s)
  Park Heewon、Miyano Satoru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 6 Pages: 3302-3302
- DOI
  10.3390/ijms25063302
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24947
[Journal Article] Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification2023
- Author(s)
  Park Heewon、Imoto Seiya、Miyano Satoru
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 8 Pages: e0286044-e0286044
- DOI
  10.1371/journal.pone.0286044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24947
[Journal Article] Gene Regulatory Network-Classifier: Gene Regulatory Network-Based Classifier and Its Applications to Gastric Cancer Drug (5-Fluorouracil) Marker Identification2023
- Author(s)
  Park Heewon、Imoto Seiya、Miyano Satoru
- Journal Title
  
  Journal of Computational Biology
  
  Volume: 30 Issue: 2 Pages: 223-243
- DOI
  10.1089/cmb.2022.0181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24947, KAKENHI-PROJECT-22K12259
[Journal Article] Uncovering Molecular Mechanisms of Drug Resistance via Network-Constrained Common Structure Identification2022
- Author(s)
  Heewon Park, Rui Yamaguchi, Seiya Imoto, Satoru Miyano
- Journal Title
  
  Journal of Computational Biology
  
  Volume: 29(3) Issue: 3 Pages: 257-275
- DOI
  10.1089/cmb.2021.0314
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20402
[Journal Article] Computational Tactics for Precision Cancer Network Biology2022
- Author(s)
  Park Heewon、Miyano Satoru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 22 Pages: 14398-14398
- DOI
  10.3390/ijms232214398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24947, KAKENHI-PROJECT-22K12259
[Journal Article] PredictiveNetwork: predictive gene network estimation with application to gastric cancer drug response-predictive network analysis2022
- Author(s)
  Park Heewon、Imoto Seiya、Miyano Satoru
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 23 Issue: 1 Pages: 1-25
- DOI
  10.1186/s12859-022-04871-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24947, KAKENHI-PROJECT-22K12259
[Journal Article] Xprediction: Explainable EGFR-TKIs response prediction based on drug sensitivity specific gene networks2021
- Author(s)
  Heewon Park, Rui Yamaguchi, Seiya Imoto, Satoru Miyano
- Journal Title
  
  PLOS ONE
  
  Volume: 未定 Issue: 5 Pages: e0261630-e0261630
- DOI
  10.1371/journal.pone.0261630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20402
[Journal Article] Global gene network exploration based on explainable artificial intelligence approach2020
- Author(s)
  Park Heewon、Maruhashi Koji、Yamaguchi Rui、Imoto Seiya、Miyano Satoru
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 11 Pages: e0241508-e0241508
- DOI
  10.1371/journal.pone.0241508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20402, KAKENHI-PROJECT-18H03328, KAKENHI-PROJECT-18H03329
[Journal Article] Automatic sparse principal component analysis2020
- Author(s)
  Park Heewon、Yamaguchi Rui、Imoto Seiya、Miyano Satoru
- Journal Title
  
  Canadian Journal of Statistics
  
  Volume: Online first Issue: 3 Pages: 1-24
- DOI
  10.1002/cjs.11579
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20402, KAKENHI-PROJECT-18H03329
[Journal Article] Robust sample-specific stability selection with effective reror control2019
- Author(s)
  Park H, Yamada M, Imoto S, Miyano S
- Journal Title
  
  J Comput Biol
  
  Volume: 26(3) Issue: 3 Pages: 202-217
- DOI
  10.1089/cmb.2018.0180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H06299
[Journal Article] Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks2018
- Author(s)
  Park H, Shimamura T, Imoto S, Miyano S
- Journal Title
  
  J Comput Biol
  
  Volume: 25(2) Issue: 2 Pages: 130-145
- DOI
  10.1089/cmb.2017.0120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15H05325
[Journal Article] A novel adaptive penalized logistic regression for uncovering biomarker associated with anti-cancer drug sensitivity2017
- Author(s)
  Park H, Shiraishi Y, Imoto S, Miyano S
- Journal Title
  
  EEE/ACM Trans Comput Biol Bioinform
  
  Volume: - Issue: 4 Pages: 771-782
- DOI
  10.1109/tcbb.2016.2561937
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05912
[Journal Article] Interaction-based feature selection for uncovering cancer driver genes through copy number-driven expression level2017
- Author(s)
  Park H, Niida A, Imoto S, Miyano S
- Journal Title
  
  J Comput Biol
  
  Volume: 24(2) Issue: 2 Pages: 138-152
- DOI
  10.1089/cmb.2016.0140
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05912
[Journal Article] Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells2015
- Author(s)
  T. Kato, H. Inoue, S. Imoto, Y. Tamada, T. Miyamoto, Y. Matsuo, Y. Nakamura and J.H. Park
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 14 Pages: 17652-17664
- DOI
  10.18632/oncotarget.7755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20965, KAKENHI-PLANNED-15H05912
[Journal Article] Recursive random lasso (RRLasso) for identifying anti-cancer drug targets2015
- Author(s)
  Park H, Imoto S, Miyano S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 11 Pages: 147-152
- DOI
  10.1371/journal.pone.0141869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H05707
[Presentation] Comprehensive gene regulatory network analysisbased on explainable AI2021
- Author(s)
  Heewon Park
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20402

1. MIYANO SATORU (50128104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 白石友一 (70516880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 山口類 (90380675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 島村徹平 (00623943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 新井田厚司 (00772493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 片山琴絵 (40581195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 張耀中 (60817138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 井元清哉 (10345027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 玉田嘉紀 (80435495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小川誠司 (60292900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 西川博嘉 (10444431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤俊朗 (70365245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 衣斐寛倫 (00645145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 丸橋弘治 (20417504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

PARK HEEWON ＰＡＲＫ ＨＥＥＷＯＮ

Park Heewon PARK HEEWON

Research Projects

Research Products

Co-Researchers

Understanding of clonal evolution in cancer and normal tissues

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

説明可能AIによる１細胞計測大規模ネットワークデータからの知識発見技術の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Develop explainable AI strategies for uncovering molecular mechanism behind disease based on gene network analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Statistical Modeling for Evidence based Personalized MedicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neodimensional exploration for cancer systems by supercomputing and innovative information technology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Differential Gene Regulatory Network Analysis between Azacitidine-Sensitive and -Resistant Cell Lines2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene Regulatory Network-Classifier: Gene Regulatory Network-Based Classifier and Its Applications to Gastric Cancer Drug (5-Fluorouracil) Marker Identification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Uncovering Molecular Mechanisms of Drug Resistance via Network-Constrained Common Structure Identification2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational Tactics for Precision Cancer Network Biology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PredictiveNetwork: predictive gene network estimation with application to gastric cancer drug response-predictive network analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Xprediction: Explainable EGFR-TKIs response prediction based on drug sensitivity specific gene networks2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global gene network exploration based on explainable artificial intelligence approach2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automatic sparse principal component analysis2020

Author(s)

Journal Title

DOI

Data Source

PARK HEEWON ＰＡＲＫＨＥＥＷＯＮ