Nakayama Keiichi 中山敬一

… Alternative Names

NAKAYAMA Keiichi 中山敬一

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Researcher Number	80291508
Other IDs
Affiliation (Current)	2024: 東京科学大学, 総合研究院, 特任教授
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 高等研究院, 特別栄誉教授 2014 – 2023: 九州大学, 生体防御医学研究所, 主幹教授 1998 – 2017: Medical Institute of Bioregulation, Kyushu University, Professor, 生体防御医学研究所, 教授 2015: 九州大学生体防御医学研究所, 教授 2009: Kyushu University, 生体防御医学研究所, 主幹教授 … More 2001: 九州大学, 生体防御医学研究所, 助教授 2001: 九州大学, 生体防御学研究所, 教授 2000 – 2001: Kyushu Univ, Dept of Med, Prof, 大学院・医学研究院, 教授 1997: 九大, 生体防御医学研究所, 教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Neurochemistry/Neuropharmacology / Biological Sciences / Biological Sciences / Pathological medical chemistry / Functional biochemistry / Experimental pathology / Molecular biology / Tumor biology … More / Psychiatric science / General physiology / Nerve anatomy/Neuropathology / Cell biology … More Except Principal Investigator Biological Sciences / Tumor biology / Circulatory organs internal medicine / Biological Sciences / Gastroenterology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / System genome science / General medical chemistry / Bioinformatics/Life informatics / Immunology / Neurology / Molecular biology / Functional biochemistry / Cell biology / Developmental biology / Carcinogenesis / Experimental pathology Less
Keywords	Principal Investigator 細胞周期 / ノックアウトマウス / プロテオミクス / ユビキチン化 / 代謝 / 幹細胞 / ユビキチンリガーゼ / Skp2 / KPC / p27 … More / がん / ユビキチン / PKC-δ / Mad / Nedd-4 / Myc / UFD2 / MJD / VCP / ポリグルタミン病 / シグナル伝達 / PKCδ / p57 / CDKインヒビター / 神経 / リン酸化 / アポトーシス / リプログラミング / プロテオーム / 適応 / 細胞競合 / ネットワーク / 競合 / ヒステリシス / インスリン抵抗性 / 慢性炎症 / 神経発生 / 自閉症 / Knockout mouse / Posttranslational modification / Mass analysis / Phosphorylation / Signal transduction / Proteomics / Embryonic and genetic engineering / 翻訳後修飾 / 質量分析 / 発生工学 / chimeric-protein / Ubiquitiylation / プロテアゾームインヒビター / Nedd4 / Max / キメラタンパク / Ubiquitylation / polyglutamine Disease / VPC / MJD1 / SCF complex / ubiquitin / CDK inhibitor / Cell Cycle / p27Kip1 / サイクリンE / RING finger / G0-G1移行期 / CRM1 / タンパク分解 / SCF複合体 / polyglutamine disease / Machado-Joseph Disease / proteolysis / neurodegenerative disease / inclusion body / ubiquitination / ユビキチン鎖伸長因子(E4) / UFD2a / マシャド・ジョセフ病 / Machado-Joseph病 / 蛋白質分解 / 封入体 / 神経変性疾患 / proliferation control / B cell / singal transduction / knockout mice / apoptosis / ICE様プロテアーゼ / ES細胞 / ジーンターゲティング / プロテインキナーゼC / 増殖制御 / B細胞 / ワールブルグ効果 / 行動解析 / CHD8 / 行動 / クロマチンリモデリング / 自閉症スペクトラム障害 / 再生医学 / 再生医科学 / 低分子GTP結合タンパク質 / 高次脳機能 / シナプス / 低分子Gタンパク質 / 細胞内輸送 / GO期 / 遺伝子改変動物 / 癌治療 / G0期 / 白血病 / CDK阻害分子 / 静止期 / 癌幹細胞 / 突起 / 再生 / Rab / 小胞輸送 / 突起形成 / リサイクルエンドソーム / ERK / NGF / FYVEドメイン / 痙性対麻痺 / Rab11 / 硫酸化脂質 / Protrudin / スパイン / 神経成長因子 / Gタンパク質 / 膜輸送 / 神経突起 / 神経細胞 / UBAドメイン / UBLドメイン / 発がん / プロテアソーム / コンディショナルノックアウトマウス / p53 / Fbw7 / c-Myc / サイクリン / タンパク質分解 … More Except Principal Investigator 細胞周期 / ユビキチン / ユビキチン化 / FKBP38 / p27 / プロテオミクス / タンパク質分解 / プロテアソーム / Protrudin / タンパク質複合体 / 小胞膜輸送 / 神経疾患 / 神経管形成 / 神経細胞分化 / ユビキチンリガーゼ / 蛋白分解 / Skp2 / エピジェネティクス / NF-κB / プロテオーム / Rab / 発生・分化 / 神経変性疾患 / ノックアウトマウス / KPC / Cul-1 / Skp1 / サイクリン依存性キナーゼ阻害分子 / 代謝 / VCP / UFD2 / MJD / protein degradation / SCF complex / RNA helicase / nucleolus / GTR2 / GTR1 / p27^<Kip1> / proteasome / ubiquitination / fibrosis / inflammation / arteriosclerosis / MCP-1 / nitric oxide / gene transfer / 炎症 / ケモカイン / monocyte chemoattractant protein-1 / 転写因子 / アンジオテンシンII / 動脈硬化 / 一酸化窒素 / 血管内皮 / 発がん / 癌 / 肝再生 / トランスクリプトーム / 肝臓病学 / 再生 / 神経科学 / 脳・神経 / シグナル伝達 / リン酸化 / 膜輸送 / ポリグルタミン病 / シャペロン / β-catenin / IκBα / ユピキチン化 / オミクス計測 / 代謝アダプテーション / トランスオミクス / 幹細胞 / 細胞老化 / 幹細胞老化 / Autism / プロトルーディン / PKD / 細胞内情報伝達 / モノアミン / 低酸素 / 転移ニッチ / がんニッチ / がん転移 / 質量分析計 / がん / ワールブルグ効果 / がん代謝 / Ubiquitin / Protein Degradation / Cell Cycle / mass spectrometry / lymphocyte / phosphorylation / ubiquitylation / proteome / 質量分析 / リンパ球 / Runx family / gene silencing / CD4 gene / epigenetics / silencing / Runx / T細胞分化 / CD4 / Runxファミリィー / Runxファミリー / サイレンシング / CD4遺伝子 / エピジェネティックス / U-box protein / Quality control / Neurodegenerative disease / Ubiquitin ligase / ubiquitin / U-ボックス / カテニン / SCF / U-ボックスタンパク質 / 品質管理 / ubiqtuin ligase / RRAGC / RRAGA / RagA / RNA結合タンパク質 / RNA結合タンパク / Rag A / RCC1 / ubiquitin ligase / RRAG C / RRAG A / F-box protein / knock-out mouse / Ubiquitin Ligase / 中心体 / SCF複合体 / F-boxタンパク / アポE欠損マウス / 繊維化 / 単球走化因子 / NF-KB / 遺伝子導入 / cyclin-dependent kinase / lung cancer / p27ィイD1Kip1ィエD1 / プロセッシング / ユビキチン-プロテアソーム / サイクリン依存性キナーゼ / 肺がん / colon cancer / F-box蛋白質 / 大腸がん / β-カテニン / 組織因子 / アンジオテンシン変換酵素 / p57 / 起源 / 細胞分裂 / 神経幹細胞 / 分子標的治療 / 幹細胞ニッチ / 癌幹細胞 / 生体分子 / 細胞・組織 / 酵素 / ゲノム / 生殖細胞 / クロマチン / 骨髄移植 / protrudin / 遺伝子操作動物 / エピジェネテックス / 蛋白質分解 / 分化 / 転写制御 / ノックアウト / クロマチン制御 / 形態形成 / 心筋細胞 / 細胞増殖 / 分子遺伝学 / イモリ / マウス / 発生 / 細胞分化 / 増殖停止 / 細胞周期、 / 神経化学 / コビキチン / 脳神経疾患 / シグナル伝津 / 中枢神経系 / 神経突起伸長 / 領域形成 / 脳 / Myc / E4B / 神経変性性疾患 / たんぱく質分解 / β-TrCP / FWD1 / F-box蛋白 / Yeast three-hybrid法 / 血管新生 / IKBa / NFkB / アデノウィルス / 遺伝子治療 / VEGF受容体 / p53 / Dominan-negative H-Ras / プロセシング Less

幹細胞における時空間リプログラミングの機構解明と疾患との関わりの研究Principal Investigator
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tokyo Medical and Dental University
  Kyushu University
Investigation for mechanisms underlying cell cycle regulation and metabolism in stem cellsPrincipal Investigator
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
幹細胞における細胞周期制御と代謝系との連関に関する基盤的研究Principal Investigator
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Kyushu University
代謝リモデリングによる適者生存メカニズムの研究Principal Investigator
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
がん細胞の代謝アダプテーションPrincipal Investigator
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Trans-omic analysis of metabolic adaptation
- Principal Investigator
  
  Kueoda Shinya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidating the metabolic enzymes network in hypoxic cells using next-generation proteomics
- Principal Investigator
  
  Oshikawa Kiyotaka
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
新規モデルマウスを用いた自閉症マイクロエンドフェノタイプの解明Principal Investigator
- Principal Investigator
  
  中山敬一
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Deciphering the signal transduction pathway linking nutrition and inflammationPrincipal Investigator
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Elucidation of the mechanisms for Fbxw7 to suppress cancer metastasis in cancer niches
- Principal Investigator
  
  Yumimoto Kanae
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Mechanism of PKD activation for monoamine release
- Principal Investigator
  
  Shirane Michiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya City University
  Kyushu University
Epigenetic regulation of stem cell aging and organismal aging
- Principal Investigator
  
  Nishiyama Masaaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
  Kyushu University
Elucidation of Warburg effect in cancer with the next-generation proteomicsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Integrative study for functional analyses of stem cell maintenance factors and visualization of stem cellsPrincipal Investigator
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  General physiology
- Research Institution
  Kyushu University
Functional analysis of a candidate gene for autism spectrum disorderPrincipal Investigator
- Principal Investigator
  
  Nakayama Keiichi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Kyushu University
Identification of an embryonic origin of adult neural stem cells
- Principal Investigator
  
  FURUTACHI Shohei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo
Elucidating the molecular mechanism of Warburg effect in cancer cells with iMRM
- Principal Investigator
  
  Oshikawa Kiyotaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Method for determination of cellar pathway structure using multidimensional proteomics
- Principal Investigator
  
  Masaki Matsumoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Kyushu University
Elucidation of the mechanisms that control aging and cancer by chromatin remodeling
- Principal Investigator
  
  NISHIYAMA MASAAKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Kyushu University
Development of Novel Treatment Strategies Targeting Cancer Stem Cells
- Principal Investigator
  
  AKASHI Koichi
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Elucidation of mechanism underlying cell cycle regulation and development of therapeutic strategyPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Deciphering the role of protrudin regulating neuronal vesicular transportPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University
高感度定量プロテオミクスを用いたユビキチンリガーゼ基質探索
- Principal Investigator
  
  松本雅記
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
生殖細胞特異的クロマチン修飾因子の機能解析
- Principal Investigator
  
  束田裕一
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
The basic analysis of cell cycle association molecules by controlling the function aiming at application to liver regeneration treatment.
- Principal Investigator
  
  NAGAHAMA Hiroyasu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
神経分化と機能制御における膜輸送の役割
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
神経機能調節におけるRabファミリーの制御機構
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Mechanisms of cell cycle arrest and its interaction with cell differentiation during development
- Principal Investigator
  
  TAKEUCHI Takashi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tottori University
  Mitsubishi Kagaku Institute of Life Sciences
神経変性疾患における膜輸送システムの関与の解析
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
The basic analysis of cell cycle association molecules by controlling the function aiming at application to liver regeneration treatment
- Principal Investigator
  
  NAGAHAMA Hiroyasu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
リン酸化ペプチドの網羅的解析のための新技術開発
- Principal Investigator
  
  Masaki Matsumoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
神経管形成における多機能シャペロンFKBP38の機能解析
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
異常タンパク質蓄積による神経変性疾患発症の分子機構の解明
- Principal Investigator
  
  松本雅記, 嘉村巧
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
  Nagoya University
ProtrudinによるRabおよび膜輸送の制御機構の解析
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Deciphering the mechanisms underlying cancer development induced by deregulation of proteolysisPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
中枢神経系領域形成におけるFKBP38の機能解析
- Principal Investigator
  
  SHIRANE Michiko
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
異常タンパク質蓄積による神経変性疾患発症の分子機構の解明
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
新規Cullin/Rbx型E3ユビキチンリガーゼ群の機能解析
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Isolation and characterization of protrudin, a master regulator of neurite formationPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Cell biology
- Research Institution
  Kyushu University
神経突起伸長におけるFKBP38の機能解析
- Principal Investigator
  
  白根道子
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
異常タンパク質蓄積による神経変性疾患発症の分子機構の解明
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
細胞内タンパク質の特異的分解制御による癌に対する遺伝子治療法の確立
- Principal Investigator
  
  畠山鎮次
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Hokkaido University
Comprehensive analysis of molecules related for antigen receptor signaling
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  HOKKAIDO UNIVERSITY
Analysis of degradation of cell cycle regulators Kip family
- Principal Investigator
  
  KAMURA Takumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
  Kyushu University
プロテアソームへのユビキチン化基質のターゲッテング機構の解析
- Principal Investigator
  
  嘉村巧
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Analysis of the PKC-δ Signaling Pathway by Proteomics with Embryonic and Genetic EngeneeringPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  KYUSHU UNIVERSITY
Study of molecular mechanisms of CD4 silencing and role s of Runx proteins during lymphocyte development
- Principal Investigator
  
  TANIUCHI Ichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  RIKEN (Institute of Physical and Chemical Research)
  Kyushu University
プロテアソームへのユビキチン化基質のターゲッテング機構の解析
- Principal Investigator
  
  KAMURA Takumi
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Regulation of by protein degradation and transport.
- Principal Investigator
  
  SEKIGUCHI Takeshi
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
New clearance system of abnormal protein in Polyglutammine diseasePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyushu University
New cancer therapy by degradation of specific proteinsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
Establishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteinsEstablishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteins
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Investigation into the molecular mechanisms underlying proteolysis of CDK inhibitor p27Principal Investigator
- Principal Investigator
  
  NAKAYAMA Keiichi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Functional analysis of ubiquitin ligase by knock-out mise
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERSITY
細胞周期調節分子の分解制御に関する研究-マウスSCF複合体の遺伝子クローニングと解析-
- Principal Investigator
  
  畠山鎮次
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-_B AND MCP-1
- Principal Investigator
  
  EGASHIRA Kensuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Identification of the factors mediating ubiquitination of inclusion body in neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Kei-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Medical Institute of Bioregulation, Kyushu University
サイクリン依存性キナーゼ阻害分子の分解機構の解明
- Principal Investigator
  
  NAKAYAMA Keiko
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
多角的戦略に基づく組換えアデノウィルスによる固形癌の遺伝子治療法の開発
- Principal Investigator
  
  上野光
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
細胞周期調節分子の分解制御に関する研究 - Yeast three-hybrid法の確立と応用 -
- Principal Investigator
  
  畠山鎮次
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
MOLECULAR MECHANISMS OF CARDIOVASCULAR REMODELING INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE SYNTHESIS : ROLE OF NF-κB AND MCP-1
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Identification and functional analysis of S phase promoting complex in mammalian cell growth
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  KYUSHU UNIVERSITY
Regulation of degradation of p27Kip1, one of CDK inhibitory protein, for cancer therapy
- Principal Investigator
  
  KITAGAWA Masatoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  KYUSHU UNIVERSITY
Analysis of sinnalling pathway of apoptosis degradation using PKCδ gene-targeting micePrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Kei-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University

[Book] 実験医学2021年7月号2021
- Author(s)
  中山敬一
- Total Pages
  129
- Publisher
  羊土社
- ISBN
  9784758125451
- Data Source
  KAKENHI-PROJECT-18H05215
[Book] 実験医学2017
- Author(s)
  片山　雄太，西山　正章，中山　敬一
- Total Pages
  138
- Publisher
  羊土社
- ISBN
  9784758101592
- Data Source
  KAKENHI-PROJECT-15K06835
[Book] LabDroidを用いた高精度プロテオミクス in 実験医学別冊「あなたのラボにAI X ロボットがやってくる：研究に生産性と創造性をもたらすテクノロジー」2017
- Author(s)
  松本雅記、中山敬一
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-17H06301
[Book] がん抑制因子のがんニッチ細胞における機能2016
- Author(s)
  弓本佳苗, 中山敬一
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15H05575
[Book] 分子精神医学2016
- Author(s)
  川村　敦生, 西山　正章, 中山　敬一
- Total Pages
  3
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15K06835
[Book] がん基盤生物学ー革新的シーズ育成に向けてー2013
- Author(s)
  武石昭一郎、中山敬一
- Total Pages
  8
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-25221303
[Book] がん基盤生物学ー革新的シーズ育成に向けてー2013
- Author(s)
  中山　敬一
- Total Pages
  6
- Publisher
  南山堂
- Data Source
  KAKENHI-PLANNED-22130003
[Book] 実験医学別冊「見つける、量る、可視化する！質量分析実験ガイド」2013
- Author(s)
  松本雅記、中山敬一
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25221303
[Book] 疾患モデルの作製と利用ーがん2012
- Author(s)
  沖田康孝, 中山敬一
- Data Source
  KAKENHI-PROJECT-22240038
[Book] タンパク質分解. イラストで徹底理解するシグナル伝達キーワード事典2012
- Author(s)
  中山敬一, 蟹江共春
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22240038
[Book] ユビキチン. 生物機能モデルと新しいリソース・リサーチツール2011
- Author(s)
  諸石寿朗, 中山敬一
- Data Source
  KAKENHI-PROJECT-22240038
[Book] プロテオミクスが拓く細胞周期研究2010
- Author(s)
  松本雅記、中山敬一
- Total Pages
  6
- Publisher
  共立出版,東京
- Data Source
  KAKENHI-PLANNED-22130003
[Book] G0期とその周辺:細胞周期の停止と再増殖の分子メカニズム2010
- Author(s)
  洲崎悦生, 中山敬一
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-22240038
[Book] 創薬・タンパク質研究のためのプロテオミクス解析2010
- Author(s)
  松本雅記, 中山敬一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22240038
[Book] プロテオミクスが拓く細胞周期研究. 細胞周期フロンティア2010
- Author(s)
  松本雅記, 中山敬一
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-22240038
[Book] プロテオミクスが拓く細胞周期研究2010
- Author(s)
  松本雅記、中山敬一
- Total Pages
  6
- Publisher
  共立出版,東京
- Data Source
  KAKENHI-PROJECT-22240038
[Book] 細胞周期:細胞増殖の制御メカニズム(中山敬一, 中山啓子編)2008
- Author(s)
  中山敬一, 中山啓子
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-17013067
[Book] 細胞周期 : 細胞増殖の制御メカニズム2008
- Author(s)
  中山敬一, 中山啓子
- Total Pages
  302
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-17107004
[Book] 細胞周期:細胞増殖の制御メカニズム. 細胞周期:細胞増殖の制御メカニズム(中山敬一, 中山啓子編)2008
- Author(s)
  中山敬一, 中山啓子
- Publisher
  東京
- Data Source
  KAKENHI-PROJECT-17107004
[Book] 細胞周期 : 細胞増殖の制御メカニズム2008
- Author(s)
  中山敬一, 中山啓子
- Total Pages
  302
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-17013067
[Book] 細胞周期ブレーキp27の分解と発がん. 発がんの分子機構と防御(笹月健彦, 野田哲生編)2006
- Author(s)
  中山敬一
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-17013067
[Book] 「発がんの分子機構と防御」細胞周期ブレーキp27の分解と発がん2005
- Author(s)
  中山敬一
- Total Pages
  15
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-17107004
[Book] キーワードで理解する細胞周期イラストマップ (中山敬一・編)2005
- Author(s)
  中山敬一
- Total Pages
  190
- Publisher
  羊土社 (東京)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Book] 「発がんの分子機構と防御」細胞周期ブレーキp27の分解と発がん2005
- Author(s)
  中山敬一
- Total Pages
  15
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-17013067
[Book] 決定版!プロテオーム解析マニュアル(礒辺俊明, 高橋信弘編)2004
- Author(s)
  松本雅記, 中山敬一
- Total Pages
  8
- Publisher
  羊土社(東京)
- Data Source
  KAKENHI-PROJECT-15370060
[Book] 決定版!プロテオーム解析マニュアル(礒辺俊明, 高橋信弘編)2004
- Author(s)
  松本雅記, 中山敬一
- Total Pages
  8
- Publisher
  羊土社(東京)
- Data Source
  KAKENHI-PROJECT-12213097
[Book] わかる実験医学シリーズ「ユビキチンがわかる」(田中啓二編)2004
- Author(s)
  中山敬一, 中山啓子
- Total Pages
  8
- Publisher
  羊土社(東京)
- Data Source
  KAKENHI-PROJECT-13043039
[Book] 細胞周期がわかる(中山敬一・編)2001
- Author(s)
  中山敬一
- Total Pages
  140
- Publisher
  羊土社(東京)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Book] 細胞周期ブレーキp27の分解と発がん. 発がんの分子機構と防御(笹月健彦, 野田哲生編)
- Author(s)
  中山敬一
- Publisher
  東京大学出版会(東京)
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism2022
- Author(s)
  Uematsu Saori、Ohno Satoshi、Tanaka Kaori Y.、Hatano Atsushi、Kokaji Toshiya、Ito Yuki、Kubota Hiroyuki、Hironaka Ken-ichi、Suzuki Yutaka、Matsumoto Masaki、Nakayama Keiichi I.、Hirayama Akiyoshi、Soga Tomoyoshi、Kuroda Shinya
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 2 Pages: 103787-103787
- DOI
  10.1016/j.isci.2022.103787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06577, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-17H06300
[Journal Article] Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium2022
- Author(s)
  Higa Tsunaki、Okita Yasutaka、Matsumoto Akinobu、Nakayama Shogo、Oka Takeru、Sugahara Osamu、Koga Daisuke、Takeishi Shoichiro、Nakatsumi Hirokazu、Hosen Naoki、Robine Sylvie、Taketo Makoto M.、Sato Toshiro、Nakayama Keiichi I.
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1500-1500
- DOI
  10.1038/s41467-022-29165-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19J20466, KAKENHI-PROJECT-21K07155
[Journal Article] Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.2022
- Author(s)
  Mise S#, Matsumoto A#*, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI*.
- Journal Title
  
  Nat. Commun.
  
  Volume: 13(1) Issue: 1 Pages: 1071-1071
- DOI
  10.1038/s41467-022-28677-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-20K21397, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-17H06304, KAKENHI-PROJECT-20J11940, KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-21H02751, KAKENHI-PROJECT-20K15101, KAKENHI-PLANNED-20H05928
[Journal Article] Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons2021
- Author(s)
  Ichihara Kazuya、Matsumoto Akinobu、Nishida Hiroshi、Kito Yuki、Shimizu Hideyuki、Shichino Yuichi、Iwasaki Shintaro、Imami Koshi、Ishihama Yasushi、Nakayama Keiichi I
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 13 Pages: 7298-7317
- DOI
  10.1093/nar/gkab549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04844, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-21H02404, KAKENHI-PROJECT-20J20906, KAKENHI-PROJECT-21J15131, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-21K17856, KAKENHI-PROJECT-16H06276
[Journal Article] The autism-associated protein CHD8 is required for cerebellar development and motor function2021
- Author(s)
  Kawamura Atsuki、Katayama Yuta、Kakegawa Wataru、Ino Daisuke、Nishiyama Masaaki、Yuzaki Michisuke、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 1 Pages: 108932-108932
- DOI
  10.1016/j.celrep.2021.108932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05220, KAKENHI-PROJECT-20H03563, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-20H03420, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04716, KAKENHI-PUBLICLY-20H05057, KAKENHI-PUBLICLY-21H05619, KAKENHI-PROJECT-21H02847, KAKENHI-PROJECT-21J00911, KAKENHI-PROJECT-21K06421, KAKENHI-PROJECT-21K15726, KAKENHI-PROJECT-20H05628
[Journal Article] Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle2021
- Author(s)
  Egami Riku、Kokaji Toshiya、Hatano Atsushi、et al.
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 3 Pages: 102217-102217
- DOI
  10.1016/j.isci.2021.102217
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19J10234, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PLANNED-18H05431, KAKENHI-PROJECT-20H03237
[Journal Article] A ubiquitin-like protein encoded by the “noncoding” RNA TINCR promotes keratinocyte proliferation and wound healing2021
- Author(s)
  Nita Akihiro、Matsumoto Akinobu、Tang Ronghao、Shiraishi Chisa、Ichihara Kazuya、Saito Daisuke、Suyama Mikita、Yasuda Tomoharu、Tsuji Gaku、Furue Masutaka、Katayama Bumpei、Ozawa Toshiyuki、Murata Teruasa、Dainichi Teruki、Kabashima Kenji、Hatano Atsushi、Matsumoto Masaki、Nakayama Keiichi I.
- Journal Title
  
  PLOS Genetics
  
  Volume: 17 Issue: 8 Pages: 1009686-1009686
- DOI
  10.1371/journal.pgen.1009686
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-21H02751, KAKENHI-PROJECT-21K08303, KAKENHI-PROJECT-20K21386, KAKENHI-PLANNED-20H05928
[Journal Article] A universal molecular prognostic score for gastrointestinal tumors2021
- Author(s)
  Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  npj Genomic Medicine
  
  Volume: 6 Issue: 1 Pages: 6-6
- DOI
  10.1038/s41525-021-00172-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19K20403
[Journal Article] Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism2021
- Author(s)
  Cherepanov Stanislav M.、Gerasimenko Maria、Yuhi Teruko、Furuhara Kazumi、Tsuji Chiharu、Yokoyama Shigeru、Nakayama Keiichi I.、Nishiyama Masaaki、Higashida Haruhiro
- Journal Title
  
  BMC Neuroscience
  
  Volume: 22 Issue: 1 Pages: 32-32
- DOI
  10.1186/s12868-021-00631-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-21H02847
[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021
- Author(s)
  Maimaiti Maihulan、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumi、Matsusaka Keisuke、Xu Minhui、Ando Keisuke、Saito Shinpei、Wakai Ken、Imamura Yusuke、Nakayama Keiichi、Kanai Yoshikatsu、Kaneda Atsushi、Ikehara Yuzuru、Ikeda Jun-Ichiro、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11478-11478
- DOI
  10.1038/s41598-021-90748-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K09572, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver2021
- Author(s)
  Matsuzaki Fumiko、Uda Shinsuke、Yamauchi Yukiyo、Matsumoto Masaki、Soga Tomoyoshi、Maehara Kazumitsu、Ohkawa Yasuyuki、Nakayama Keiichi I.、Kuroda Shinya、Kubota Hiroyuki
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 8 Pages: 109569-109569
- DOI
  10.1016/j.celrep.2021.109569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06577, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04847, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-18K15011, KAKENHI-PROJECT-20H03237, KAKENHI-PLANNED-17H06300
[Journal Article] Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders2021
- Author(s)
  Johmura Yoshikazu、Yamanaka Takehiro、Omori Satotaka、Wang Teh-Wei、Sugiura Yuki、Matsumoto Masaki、Suzuki Narumi、Kumamoto Soichiro、Yamaguchi Kiyoshi、Hatakeyama Seira、Takami Tomoyo、Yamaguchi Rui、Shimizu Eigo、Ikeda Kazutaka、Okahashi Nobuyuki、Mikawa Ryuta、Suematsu Makoto、Arita Makoto、Sugimoto Masataka et al
- Journal Title
  
  Science
  
  Volume: 371 Issue: 6526 Pages: 265-270
- DOI
  10.1126/science.abb5916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H04116
[Journal Article] The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells2021
- Author(s)
  Nita Akihiro、Muto Yoshiharu、Katayama Yuta、Matsumoto Akinobu、Nishiyama Masaaki、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 5 Pages: 108688-108688
- DOI
  10.1016/j.celrep.2021.108688
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21397, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05220, KAKENHI-PROJECT-18H02707, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-20H03563, KAKENHI-PROJECT-20K21650, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-21H02847
[Journal Article] Identification and characterization of novel proteins associated with CHD42021
- Author(s)
  Sakaguchi Chihiro、Ichihara Kazuya、Nita Akihiro、Katayama Yuta、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 27 Issue: 1 Pages: 61-71
- DOI
  10.1111/gtc.12909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-20J20906
[Journal Article] Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation2020
- Author(s)
  Shirane Michiko、Wada Mariko、Morita Keiko、Hayashi Nahoki、Kunimatsu Reina、Matsumoto Yuki、Matsuzaki Fumiko、Nakatsumi Hirokazu、Ohta Keisuke、Tamura Yasushi、Nakayama Keiichi I.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4576-4576
- DOI
  10.1038/s41467-020-18413-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11733, KAKENHI-PROJECT-20K06730, KAKENHI-PROJECT-20K21413, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H04907, KAKENHI-PROJECT-19H03174, KAKENHI-PROJECT-20H03255, KAKENHI-PROJECT-18K06962, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-15H05705
[Journal Article] Drug repositioning in cancer: The current situation in Japan.2020
- Author(s)
  Masuda T, Tsuruda Y, Matsumoto Y, Uchida H, Nakayama KI, Mimori K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111(4) Issue: 4 Pages: 1039-1046
- DOI
  10.1111/cas.14318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15323, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-20K08960, KAKENHI-PUBLICLY-20H05039, KAKENHI-PROJECT-19H03715
[Journal Article] A Fail-Safe System to Prevent Oncogenesis by Senescence Is Targeted by SV40 Small T Antigen2020
- Author(s)
  Kiyotaka Oshikawa, Masaki Matsumoto, Manabu Kodama, Hideyuki Shimizu, Keiichi I Nakayama
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 10 Pages: 2170-2186
- DOI
  10.1038/s41388-019-1139-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06543, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04903, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243
[Journal Article] Recent insight into the role of FBXW7 as a tumor suppressor2020
- Author(s)
  Yumimoto Kanae、Nakayama Keiichi I.
- Journal Title
  
  Seminars in Cancer Biology
  
  Volume: 未定 Pages: 1-15
- DOI
  10.1016/j.semcancer.2020.02.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-20K07592, KAKENHI-PROJECT-19J40055
[Journal Article] Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning2020
- Author(s)
  Shirane Michiko、Shoji Hirotaka、Hashimoto Yutaka、Katagiri Hiroyuki、Kobayashi Shizuka、Manabe Toshiya、Miyakawa Tsuyoshi、Nakayama Keiichi I.
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 146-146
- DOI
  10.1186/s13041-020-00693-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06901, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04876, KAKENHI-PUBLICLY-20H04907, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-20H03255
[Journal Article] A shift in glutamine nitrogen metabolism contributes to malignant progression of cancer.2020
- Author(s)
  Kodama M, Oshikawa K, Shimizu H, Yoshioka S, Takahashi M, Izumi Y, Bamba T, Tateishi C, Tomonaga T, Matsumoto M*, Nakayama KI*.
- Journal Title
  
  Nat. Commun.
  
  Volume: 11 Issue: 1 Pages: 1320-1320
- DOI
  10.1038/s41467-020-15136-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05167, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-17H06304, KAKENHI-PUBLICLY-18H04903, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-19K06543
[Journal Article] Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development.2020
- Author(s)
  Yamauchi, Y., Nita, A., Nishiyama, M., Muto, Y., Shimizu, H., Nakatsumi, H., Nakayama, K. I.
- Journal Title
  
  Genes Cells
  
  Volume: XX Issue: 6 Pages: 427-438
- DOI
  10.1111/gtc.12769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-18K19509, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-18K06962
[Journal Article] Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice2020
- Author(s)
  Kawamura Atsuki、Katayama Yuta、Nishiyama Masaaki、Shoji Hirotaka、Tokuoka Kota、Ueta Yoshifumi、Miyata Mariko、Isa Tadashi、Miyakawa Tsuyoshi、Hayashi-Takagi Akiko、Nakayama Keiichi I
- Journal Title
  
  Human Molecular Genetics
  
  Volume: - Issue: 8 Pages: 1274-1291
- DOI
  10.1093/hmg/ddaa036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22591, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-17J02750, KAKENHI-PROJECT-18K19509, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05220, KAKENHI-PLANNED-19H05723, KAKENHI-PUBLICLY-20H05057, KAKENHI-PROJECT-20H03563
[Journal Article] Knockout Mouse Models Provide Insight into the Biological Functions of CRL1 Components.2020
- Author(s)
  Nakagawa T, Nakayama K, Nakayama KI.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 1217 Pages: 147-171
- DOI
  10.1007/978-981-15-1025-0_10
- ISBN
  9789811510243, 9789811510250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281, KAKENHI-PROJECT-20K12157
[Journal Article] Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity2020
- Author(s)
  Kokaji Toshiya、Hatano Atsushi、Ito Yuki、et al.
- Journal Title
  
  Science Signaling
  
  Volume: 13 Issue: 660 Pages: 1236-1236
- DOI
  10.1126/scisignal.aaz1236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-20K19915, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-20H04847, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K24361, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-18H05431, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-18KT0020, KAKENHI-PROJECT-20H03237
[Journal Article] Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis2020
- Author(s)
  Matsuhisa Koji、Saito Atsushi、Cai Longjie、Kaneko Masayuki、Okamoto Takumi、Sakaue Fumika、Asada Rie、Urano Fumihiko、Yanagida Kanta、Okochi Masayasu、Kudo Yukitsuka、Matsumoto Masaki、Nakayama Keiichi I.、Imaizumi Kazunori
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 865-880
- DOI
  10.1096/fj.201901748r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06685, KAKENHI-PROJECT-19K16373, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06413, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H01424
[Journal Article] Artificial intelligence in oncology2020
- Author(s)
  Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Cancer Science
  
  Volume: 未定 Issue: 5 Pages: 1452-1460
- DOI
  10.1111/cas.14377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Cell cycle-dependent localization of the proteasome to chromatin2020
- Author(s)
  Kito Yuki、Matsumoto Masaki、Hatano Atsushi、Takami Tomoyo、Oshikawa Kiyotaka、Matsumoto Akinobu、Nakayama Keiichi I.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5801-5801
- DOI
  10.1038/s41598-020-62697-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04902, KAKENHI-PUBLICLY-19H04911, KAKENHI-PROJECT-18K19549, KAKENHI-PROJECT-19K06543, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21397, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-18H02707, KAKENHI-PLANNED-20H05930
[Journal Article] Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain2020
- Author(s)
  Kawamura Atsuki、Abe Yoshifumi、Seki Fumiko、Katayama Yuta、Nishiyama Masaaki、Takata Norio、Tanaka Kenji F.、Okano Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 160-160
- DOI
  10.1186/s13041-020-00699-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-20K21650, KAKENHI-PROJECT-19K16031, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H05027, KAKENHI-PUBLICLY-19H05220, KAKENHI-PUBLICLY-20H05057, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-20H03563
[Journal Article] Phase I dose‐escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer2020
- Author(s)
  Masuda Takaaki、Noda Miwa、Kogawa Takahiro、Kitagawa Dai、Hayashi Naoki、Jomori Takahito、Nakanishi Yoichi、Nakayama Keiichi I.、Ohno Shinji、Mimori Koshi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 924-931
- DOI
  10.1111/cas.14306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19K18057
[Journal Article] The role of Mediator and Little Elongation Complex in transcription termination2020
- Author(s)
  Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn P, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-20
- DOI
  10.1038/s41467-020-14849-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-19K22408, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K22401
[Journal Article] Loss of Fbxw7 impairs development of and induces heterogeneous tumor formation in the mouse mammary gland2020
- Author(s)
  Onoyama Ichiro、Nakayama Shogo、Shimizu Hideyuki、Nakayama Keiichi I.
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 24 Pages: 5515-5530
- DOI
  10.1158/0008-5472.can-20-0271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09646, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19J10033, KAKENHI-PROJECT-19K20403
[Journal Article] Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development2020
- Author(s)
  Laukoter Susanne、Beattie Robert、Pauler Florian M.、Amberg Nicole、Nakayama Keiichi I.、Hippenmeyer Simon
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 195-195
- DOI
  10.1038/s41467-019-14077-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.2020
- Author(s)
  Wakabayashi Y, Tamura Y, Kouzaki K, Kikuchi N, Hiranuma K, Menuki K, Tajima T, Yamanaka Y, Sakai A, Nakayama KI, Kawamoto T, Kitagawa K, Nakazato K.
- Journal Title
  
  Am. J. Physiol. Regul. Integr. Comp. Physiol.
  
  Volume: 318 Issue: 4 Pages: 677-690
- DOI
  10.1152/ajpregu.00089.2019
- NAID
  120007089104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01085, KAKENHI-PROJECT-15K10499, KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-18H05215
[Journal Article] A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis2020
- Author(s)
  Tsukiyama Tadasuke、Zou Juqi、Kim Jihoon、Ogamino Shohei、Shino Yuki、Masuda Takamasa、Merenda Alessandra、Matsumoto Masaki、Fujioka Yoichiro、Hirose Tomonori、Terai Sayuri、Takahashi Hidehisa、Ishitani Tohru、Nakayama Keiichi I.、Ohba Yusuke、Koo Bon-Kyoung、Hatakeyama Shigetsugu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-020-18257-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-20K21386, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04823, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-19H05411, KAKENHI-PUBLICLY-20H04895, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-19H03412, KAKENHI-PROJECT-19K22401, KAKENHI-PLANNED-20H05930
[Journal Article] The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.2020
- Author(s)
  Nakagawa T, Hattori S, Nobuta R, Kimura R, Nakagawa M, Matsumoto M, Nagasawa Y, Funayama R, Miyakawa T, Inada T, Osumi N, Nakayama KI, Nakayama K.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 4 Pages: 101030-101030
- DOI
  10.1016/j.isci.2020.101030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-20K21386, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930
[Journal Article] Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells2019
- Author(s)
  Shimizu Hideyuki、Takeishi Shoichiro、Nakatsumi Hirokazu、Nakayama Keiichi I.
- Journal Title
  
  JCI Insight
  
  Volume: 4 Issue: 4
- DOI
  10.1172/jci.insight.125138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06962, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16H06276
[Journal Article] The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment2019
- Author(s)
  Takii Ryosuke、Fujimoto Mitsuaki、Matsumoto Masaki、Srivastava Pratibha、Katiyar Arpit、Nakayama Keiich I、Nakai Akira
- Journal Title
  
  The EMBO Journal
  
  Volume: 38 Issue: 24
- DOI
  10.15252/embj.2019102566
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06490, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-18H02625
[Journal Article] SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation.2019
- Author(s)
  Sugiyama S, Yumimoto K, Inoue I, Nakayama KI
- Journal Title
  
  GENE CELLS
  
  Volume: 印刷中 Issue: 5 Pages: 354-365
- DOI
  10.1111/gtc.12680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05795, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J40055
[Journal Article] A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients2019
- Author(s)
  Shimizu H, Nakayama KI
- Journal Title
  
  EBioMedicine
  
  Volume: 46 Pages: 150-159
- DOI
  10.1016/j.ebiom.2019.07.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215
[Journal Article] Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases2019
- Author(s)
  Honda Hiroyuki、Matsumoto Masaki、Shijo Masahiro、Hamasaki Hideomi、Sadashima Shoko、Suzuki Satoshi O、Aishima Shinichi、Kai Keita、Nakayama Keiichi I、Sasagasako Naokazu、Iwaki Toru
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 78 Issue: 10 Pages: 922-929
- DOI
  10.1093/jnen/nlz075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17011, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17K07097
[Journal Article] Potentials of C-C Motif Chemokine 2-C-C Chemokine Receptor Type 2 Blockers Including Propagermanium as Anticancer Agents2019
- Author(s)
  Yumimoto Kanae、Sugiyama Shigeaki、Mimori Koshi、Nakayama Keiichi I.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 7 Pages: 2090-2099
- DOI
  10.1111/cas.14075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-19J40055, KAKENHI-PROJECT-17K07171
[Journal Article] Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis2019
- Author(s)
  Muto Yoshiharu*、Moroishi Toshiro*、Ichihara Kazuya、Nishiyama Masaaki、Shimizu Hideyuki、Eguchi Hidetoshi、Moriya Kyoji、Koike Kazuhiko、Mimori Koshi、Mori Masaki、Katayama Yuta、Nakayama Keiichi I. (*Equal contribution)
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Issue: 4 Pages: 950-965
- DOI
  10.1084/jem.20180900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19433, KAKENHI-PROJECT-18K19509, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-19H03715
[Journal Article] Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data2018
- Author(s)
  Kawata Kentaro、Yugi Katsuyuki、Hatano Atsushi、Kokaji Toshiya、Tomizawa Yoko、Fujii Masashi、Uda Shinsuke、Kubota Hiroyuki、Matsumoto Masaki、Nakayama Keiichi I.、Kuroda Shinya
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 1 Pages: 82-93
- DOI
  10.1111/gtc.12655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04801, KAKENHI-PROJECT-16K12508, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-15H05582, KAKENHI-PLANNED-16H06577, KAKENHI-PLANNED-18H05431
[Journal Article] Glutamate-rich WD40 repeat containing 1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.2018
- Author(s)
  Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, KI., Yoshida, K., Sugimoto, N. (Corresponding author), and Fujita, M.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Issue: 15 Pages: 213009-213009
- DOI
  10.1242/jcs.213009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07201, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-18J20791
[Journal Article] Combined mutation of Apc, Kras and Tgfbr2 effectively drives metastasis of intestinal cancer.2018
- Author(s)
  Sakai E, Nakayama M, Oshima H, Kouyama Y, Niida A, Fujii S, Ochiai A, Nakayama KI, Minori K, Suzuki Y, Hong CP, Ock CY, Kim SJ, Oshima M.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 5 Pages: 1334-1346
- DOI
  10.1158/0008-5472.can-17-3303
- NAID
  120006452378
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07111, KAKENHI-PROJECT-17K19608, KAKENHI-PUBLICLY-16H01576, KAKENHI-PUBLICLY-17H05616, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K07162
[Journal Article] Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb162018
- Author(s)
  Hosokawa Hiroyuki、Romero-Wolf Maile、Yui Mary A.、Ungerb?ck Jonas、Quiloan Maria L. G.、Matsumoto Masaki、Nakayama Keiichi I.、Tanaka Tomoaki、Rothenberg Ellen V.
- Journal Title
  
  Nature Immunology
  
  Volume: 19 Issue: 12 Pages: 1427-1440
- DOI
  10.1038/s41590-018-0238-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-17K19606
[Journal Article] Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum2018
- Author(s)
  Abe Yuichi、Honsho Masanori、Itoh Ryota、Kawaguchi Ryoko、Fujitani Masashi、Fujiwara Kazushirou、Hirokane Masaaki、Matsuzaki Takashi、Nakayama Keiko、Ohgi Ryohei、Marutani Toshihiro、Nakayama Keiichi I、Yamashita Toshihide、Fujiki Yukio
- Journal Title
  
  Life Science Alliance
  
  Volume: 1 Issue: 6 Pages: 1-17
- DOI
  10.26508/lsa.201800062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07337, KAKENHI-PROJECT-18K19281, KAKENHI-INTERNATIONAL-15K21743, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04795, KAKENHI-PLANNED-26116007, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16K07275, KAKENHI-PROJECT-17K15621
[Journal Article] Hidden Peptides Encoded by Putative Noncoding RNAs2018
- Author(s)
  Matsumoto A, Nakayama KI.
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 43 Issue: 1 Pages: 75-83
- DOI
  10.1247/csf.18005
- NAID
  130006742309
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19549, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-18H04902, KAKENHI-PROJECT-18H02707, KAKENHI-PROJECT-16H06276
[Journal Article] Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3.2018
- Author(s)
  Nakayama S, Yumimoto K, Kawamura A, Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 293(15) Issue: 15 Pages: 5705-5714
- DOI
  10.1074/jbc.ra117.000741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-17J02750, KAKENHI-ORGANIZER-17H06391
[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018
- Author(s)
  M Morita, T Sato, M Nomura, Y Sakamoto, Y Inoue, R Tanaka, S Ito, K Kurosawa, K Yamaguchi, Y Sugiura, H Takizaki, Y Yamashita, R Katakura, I Sato, Y Okada, H Watanabe, G Kondoh, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 12 Issue: 3 Pages: 355-367
- DOI
  10.1016/j.ccell.2018.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K09597, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K16876, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19745, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-17H06301
[Journal Article] Nuclear-cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXK12018
- Author(s)
  Nakatsumi Hirokazu、Oka Takeru、Higa Tsunaki、Shirane Michiko、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 7 Pages: 599-605
- DOI
  10.1111/gtc.12597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06962, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16H06276
[Journal Article] TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation2018
- Author(s)
  Hashimoto Yutaka、Shirane Michiko、Nakayama Keiichi I.
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 6 Pages: 418-434
- DOI
  10.1111/gtc.12583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215
[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018
- Author(s)
  Matsumoto Junichi、et al. Hatakeyama Shigetsugu、Matsumoto Masaki、Nakayama Keiichi I.、Otsuka Yutaro、Sabe Hisataka、Tsutsui Hiroyuki、Anzai Toshihisa
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 18 Pages: 2064-2066
- DOI
  10.1161/circulationaha.118.035212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks2018
- Author(s)
  Kawata Kentaro、Hatano Atsushi、Yugi Katsuyuki、Kubota Hiroyuki、Sano Takanori、Fujii Masashi、Tomizawa Yoko、Kokaji Toshiya、Tanaka Kaori Y.、Uda Shinsuke、Suzuki Yutaka、Matsumoto Masaki、Nakayama Keiichi I.、Saitoh Kaori、Kato Keiko、Ueno Ayano、Ohishi Maki、Hirayama Akiyoshi、Soga Tomoyoshi、Kuroda Shinya
- Journal Title
  
  iScience
  
  Volume: 7 Pages: 212-229
- DOI
  10.1016/j.isci.2018.07.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H06011, KAKENHI-PLANNED-17H06301, KAKENHI-PUBLICLY-18H04801, KAKENHI-ORGANIZER-18H05428, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16K12508, KAKENHI-PROJECT-17K19606, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300, KAKENHI-PROJECT-15H05582, KAKENHI-PLANNED-16H06577
[Journal Article] Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding2018
- Author(s)
  Hosokawa Hiroyuki、Ungerb?ck Jonas、Wang Xun、Matsumoto Masaki、Nakayama Keiichi I.、Cohen Sarah M.、Tanaka Tomoaki、Rothenberg Ellen V.
- Journal Title
  
  Immunity
  
  Volume: 48 Issue: 6 Pages: 1119-1134.e7
- DOI
  10.1016/j.immuni.2018.04.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-18H04000, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-17K19606
[Journal Article] The promise of targeted proteomics for quantitative network biology2018
- Author(s)
  Matsumoto Masaki、Nakayama Keiichi I
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: 54 Pages: 88-97
- DOI
  10.1016/j.copbio.2018.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19606, KAKENHI-PUBLICLY-17H05534, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16H04730
[Journal Article] Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches.2018
- Author(s)
  Hui K, Katayama Y, Nakayama KI, Nomura J, Sakurai T.
- Journal Title
  
  Neurosci. Biobehav. Rev.
  
  Volume: 印刷中 Pages: 30121-0
- DOI
  10.1016/j.neubiorev.2018.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07119, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16K01948
[Journal Article] The autism-related protein CHD8 cooperates with C/EBPβ to regulate adipogenesis.2018
- Author(s)
  Kita, Y., Katayama, Y., Shiraishi, T., Oka, T., Sato, T., Suyama, M., Ohkawa, Y., Miyata, K., Oike, Y., Shirane, M., *Nishiyama, M., *Nakayama, K. I.
- Journal Title
  
  Cell Rep.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06835
[Journal Article] A large-scale targeted proteomics assay resource based on an in vitro human proteome.2017
- Author(s)
  Matsumoto M, Matsuzaki F, Oshikawa K, Goshima N, Mori M, Kawamura Y, Ogawa K, Fukuda E, Nakatsumi H, Natsume T, Fukui K, Horimoto K, Nagashima T, Funayama R, Nakayama K, Nakayama KI.
- Journal Title
  
  Nat Methods
  
  Volume: 14 Issue: 3 Pages: 251-258
- DOI
  10.1038/nmeth.4116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14612, KAKENHI-PROJECT-16K14664, KAKENHI-PUBLICLY-17H05625
[Journal Article] SRRM4-dependent neuron-specific alternative splicing of protrudin transcripts regulates neurite outgrowth.2017
- Author(s)
  Ohnishi, T., Shirane, M., and Nakayama, K. I.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 709-719
- DOI
  10.1038/srep41130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04276, KAKENHI-PROJECT-14J03463, KAKENHI-PROJECT-25221303
[Journal Article] FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells.2017
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Kawamura, A., Nakayama, K. I.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 37 Issue: 8
- DOI
  10.1128/mcb.00470-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01516, KAKENHI-PROJECT-25221303, KAKENHI-PUBLICLY-16H01341, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-15K06835
[Journal Article] Methylphenidate and Guanfacine Ameliorate ADHD-Like Phenotypes in <b><i>Fez1</i></b>-Deficient Mice2017
- Author(s)
  Sumitomo Akiko、Saka Ayumi、Ueta Keisho、Horike Kouta、Hirai Kazuko、Gamo Nao J.、Hikida Takatoshi、Nakayama Keiichi I.、Sawa Akira、Sakurai Takeshi、Tomoda Toshifumi
- Journal Title
  
  Molecular Neuropsychiatry
  
  Volume: 3 Issue: 4 Pages: 223-233
- DOI
  10.1159/000488081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01948, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-16K14579
[Journal Article] Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.2017
- Author(s)
  Muto, Y., *Nishiyama, M., Nita, A., Moroishi, T., *Nakayama, K. I.
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 16114-16114
- DOI
  10.1038/ncomms16114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01341, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15K06835, KAKENHI-PLANNED-17H06301
[Journal Article] Robotic crowd biology with Maholo LabDroids.2017
- Author(s)
  Yachie N; Robotic Biology Consortium (inc. Masaki Matsumoto)., Natsume T.
- Journal Title
  
  Nature Biotechnology
  
  Volume: 35 Issue: 4 Pages: 310-312
- DOI
  10.1038/nbt.3758
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16J06287, KAKENHI-PROJECT-15K18466, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15K06845
[Journal Article] Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp22017
- Author(s)
  Zhang Shihao、Chen Qinghua、Liu Qingxu、Li Yuxi、Sun Xiufeng、Hong Lixin、Ji Suyuan、Liu Chengyan、Geng Jing、Zhang Weiji、Lu Zhonglei、Yin Zhen-Yu、Zeng Yuanyuan、Lin Kwang-Huei、Wu Qiao、Li Qiyuan、Nakayama Keiko、Nakayama Keiich I.、Deng Xianming、Johnson Randy L.、Zhu Liang、Gao Daming、Chen Lanfen、Zhou Dawang
- Journal Title
  
  Cancer Cell
  
  Volume: 31 Issue: 5 Pages: 669-684.e7
- DOI
  10.1016/j.ccell.2017.04.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303, KAKENHI-PLANNED-17H06301
[Journal Article] NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.2017
- Author(s)
  Fukushima H, Shimizu K, Watahiki A, Hoshikawa S, Kosho T, Oba D, Sakano S, Arakaki M
- Journal Title
  
  Mol Cell
  
  Volume: Nov 16;68(4) Issue: 4 Pages: 645-658
- DOI
  10.1016/j.molcel.2017.10.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17310, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-17H04396, KAKENHI-PROJECT-16K15811, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-17H06531
[Journal Article] Structural basis for the assembly of the Ragulator-Rag GTPase complex.2017
- Author(s)
  Yonehara R, Nada S, Nakai T, Nakai M, Kitamura A, Ogawa A, Nakatsumi H, Nakayama KI, Li S, Standley DM, Yamashita E, Nakagawa A, Okada M.
- Journal Title
  
  Nat Commun.
  
  Volume: 8 Issue: 1 Pages: 1625-1625
- DOI
  10.1038/s41467-017-01762-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19596, KAKENHI-PUBLICLY-17H06004, KAKENHI-PLANNED-26114006, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H04296
[Journal Article] Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages2017
- Author(s)
  Nakatsumi Hirokazu、Matsumoto Masaki、Nakayama Keiichi I.
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 9 Pages: 2471-2486
- DOI
  10.1016/j.celrep.2017.11.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19606, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-16H04730, KAKENHI-PLANNED-17H06301
[Journal Article] mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.2017
- Author(s)
  Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, Saghatelian A, Nakayama KI, Clohessy JG, Pandolfi PP.
- Journal Title
  
  Nature
  
  Volume: 541 Issue: 7636 Pages: 228-232
- DOI
  10.1038/nature21034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-25221303
[Journal Article] Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.2017
- Author(s)
  Muto, Y., Nishiyama, M., Nita, A., Moroishi, T., Nakayama, K. I.
- Journal Title
  
  Nature Commun.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06835
[Journal Article] p57(Kip2) knock-in mouse reveals CDK-independent contribution in the development of Beckwith-Wiedemann syndrome2016
- Author(s)
  Duquesnes, N., Callot, C., Jeannot, P., Daburon, V., Nakayama, K. I., Manenti, S., Davy, A., Besson, A.
- Journal Title
  
  J. Pathol.
  
  Volume: 239 Issue: 3 Pages: 250-261
- DOI
  10.1002/path.4721
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Journal Article] FBXL12 regulates T-cell differentiation in a cell-autonomous manner.2016
- Author(s)
  Nita, A., Nishiyama, M., Muto, Y., Nakayama, K. I.
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 5 Pages: 517-524
- DOI
  10.1111/gtc.12360
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25112517, KAKENHI-PUBLICLY-15H01516, KAKENHI-PUBLICLY-16H01341, KAKENHI-PROJECT-15K06835
[Journal Article] CHD8 haploinsufficiency results in autistic-like phenotypes in mice2016
- Author(s)
  Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T., Nakayama, K. I.
- Journal Title
  
  Nature
  
  Volume: 537 Issue: 7622 Pages: 675-679
- DOI
  10.1038/nature19357
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01291, KAKENHI-PUBLICLY-15H01516, KAKENHI-PUBLICLY-16H01341, KAKENHI-PLANNED-16H06462, KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K06835, KAKENHI-PROJECT-16K13110, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25221303
[Journal Article] Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels.2016
- Author(s)
  Inoue D, Matsumoto M, Nagase R, Saika M, Fujino T, Nakayama KI, Kitamura T.
- Journal Title
  
  Exp Hematol.
  
  Volume: 44 Issue: 3 Pages: 172-176
- DOI
  10.1016/j.exphem.2015.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-26893051, KAKENHI-PROJECT-26670465, KAKENHI-PROJECT-25290078, KAKENHI-PUBLICLY-26116721
[Journal Article] Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.2016
- Author(s)
  Hosokawa H, Tanaka T, Endo Y, Kato M, Shinoda K, Suzuki A, Motohashi S, Matsumoto M, Nakayama K, Nakayama T.
- Journal Title
  
  Nat Commun.
  
  Volume: - Issue: 1 Pages: 11289-11289
- DOI
  10.1038/ncomms11289
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14375, KAKENHI-PROJECT-25290078, KAKENHI-PUBLICLY-26116721, KAKENHI-PUBLICLY-15H01407, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16H06224
[Journal Article] F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner2015
- Author(s)
  Yumimoto, K., Akiyoshi, S., Ueo, H., Sagara, Y., Onoyama, I., Ueo, H., Ohno, S., Mori, M., Mimori, K., Nakayama, K. I.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 125 Issue: 2 Pages: 621-635
- DOI
  10.1172/jci78782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25860241, KAKENHI-PROJECT-26670608, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-15H05791
[Journal Article] FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1.2015
- Author(s)
  Watanabe K., Yumimoto K., Nakayama K. I.
- Journal Title
  
  Genes Cells
  
  Volume: 20(8) Issue: 8 Pages: 667-74
- DOI
  10.1111/gtc.12260
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01186, KAKENHI-PUBLICLY-15H01291
[Journal Article] Tissue-specific expression of histone H3 variants diversified after species separation.2015
- Author(s)
  Maehara K, Harada A, Sato Y, Matsumoto M, Nakayama KI, Kimura H, Ohkawa Y.
- Journal Title
  
  Epigenetics Chromatin
  
  Volume: 8 Issue: 1 Pages: 1-17
- DOI
  10.1186/s13072-015-0027-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18457, KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-13J04024, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-26290064, KAKENHI-PUBLICLY-26116721
[Journal Article] Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells2015
- Author(s)
  Shohei Furutachi, Hiroaki Miya, Tomoyuki Watanabe, Hiroki Kawai, Norihiko Yamasaki, Yujin Harada, Itaru Imayoshi, Mark Nelson, Keiichi I. Nakayama, Yusuke Hirabayashi and Yukiko Gotoh
- Journal Title
  
  Nature Neuroscience
  
  Volume: 印刷中 Issue: 5 Pages: 657-65
- DOI
  10.1038/nn.3989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25891008, KAKENHI-PLANNED-22123003, KAKENHI-PUBLICLY-15H01291, KAKENHI-PROJECT-15H02357, KAKENHI-PROJECT-15K15086, KAKENHI-PROJECT-25221303
[Journal Article] UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation.2015
- Author(s)
  Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, Shiotani B, Matsumoto M, Nakayama KI, Ogura H, Shiiya N, Kitagawa M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 36 Issue: 3 Pages: 394-406
- DOI
  10.1128/mcb.00809-15
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01407, KAKENHI-PROJECT-24390072, KAKENHI-PROJECT-25290044, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-25701005, KAKENHI-PUBLICLY-26116721
[Journal Article] A New Screen for Tuberculosis Drug Candidates Utilizing a Luciferase-Expressing Recombinant Mycobacterium bovis Bacillus Calmette-Guéren.2015
- Author(s)
  2)Ozeki Y, Igarashi M, Doe M, Tamaru A, Kinoshita N, Ogura Y, Iwamoto T, Sawa R, Umekita M, Enany S, Nishiuchi Y, Osada-Oka M, Hayashi T, Niki M, Tateishi Y, Hatano M, Matsumoto S.
- Journal Title
  
  PLoS One
  
  Volume: 10 Pages: 214-221
- DOI
  10.1016/j.jprot.2016.01.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15132, KAKENHI-PUBLICLY-15H01407, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-26290064, KAKENHI-PUBLICLY-26116721, KAKENHI-PROJECT-26890021, KAKENHI-PROJECT-26460344
[Journal Article] Fbxw7 suppresses cancer metastasis by inhibiting niche formation.2015
- Author(s)
  Yumimoto K., Nakayama K. I.
- Journal Title
  
  Oncoimmunology
  
  Volume: 4(8) Issue: 8 Pages: e1022308-e1022308
- DOI
  10.1080/2162402x.2015.1022308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05575
[Journal Article] FBXL12-mediated degradation of ALDH3 is essential for trophoblast differentiation during placental development.2015
- Author(s)
  Nishiyama, M., Nita, A., Yumimoto, K., Nakayama, K. I.
- Journal Title
  
  Stem Cells
  
  Volume: 33 Issue: 11 Pages: 3327-3340
- DOI
  10.1002/stem.2088
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06835, KAKENHI-PUBLICLY-25112517, KAKENHI-PUBLICLY-15H01186, KAKENHI-PUBLICLY-15H01291, KAKENHI-PUBLICLY-15H01516, KAKENHI-PROJECT-15K15086, KAKENHI-PROJECT-25221303
[Journal Article] Liver maturation deficiency in p57Kip2-/- mice occurs in a hepatocytic p57Kip2 expression-independent manner.2015
- Author(s)
  agida A, Chikada H, Ito K, Umino A, Kato-Itoh M, Yamazaki Y, Sato H, Kobayashi T, Yamaguchi T, Nakayama KI, Nakauchi H, Kamiya A.
- Journal Title
  
  Dev Biol.
  
  Volume: 407(2) Issue: 2 Pages: 331-43
- DOI
  10.1016/j.ydbio.2015.07.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460358, KAKENHI-PROJECT-26293178, KAKENHI-PROJECT-25221303
[Journal Article] Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells2014
- Author(s)
  Shoichiro Takeishi, Keiichi I. Nakayama
- Journal Title
  
  British Journal of Cancer
  
  Volume: 111 Issue: 6 Pages: 1054-1059
- DOI
  10.1038/bjc.2014.259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Journal Article] HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism2014
- Author(s)
  Moroishi T., Yamauchi T., Nishiyama M., Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670517
[Journal Article] p57 regulates T cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling2014
- Author(s)
  Matsumoto A., Takeishi S., Nakayama KI.
- Journal Title
  
  Blood
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] Reconstruction of insulin signal flow from phosphoproteome and metabolome data2014
- Author(s)
  Yugi, K., Kubota, H., Toyoshima, Y., Noguchi, R., Kawata, K., Komori, Y., Uda, S., Kunida, K., Tomizawa, Y., Funato, Y., Miki, H., Matsumoto, M., Nakayama, K.I., Kashikura, K., Endo, K., Ikeda, K., Soga, T., Kuroda, S.
- Journal Title
  
  Cell Rep.
  
  Volume: 8 Issue: 4 Pages: 1171-1183
- DOI
  10.1016/j.celrep.2014.07.021
- NAID
  120005537752
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PUBLICLY-25134714, KAKENHI-PROJECT-25290078, KAKENHI-PLANNED-26111007, KAKENHI-PUBLICLY-26112711, KAKENHI-PUBLICLY-26120507, KAKENHI-PROJECT-26291042, KAKENHI-PROJECT-26460364, KAKENHI-PROJECT-26640080, KAKENHI-PUBLICLY-26116721
[Journal Article] Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.2014
- Author(s)
  Lu Z
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3463-3463
- DOI
  10.1038/ncomms4463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25221303
[Journal Article] Identification and characterization of a neuron-specific isoform of protrudin.2014
- Author(s)
  Ohnishi, T., *Shirane, M., Hashimoto, Y., Saita, S., and Nakayama, K. I.
- Journal Title
  
  Genes Cells
  
  Volume: 19 Issue: 2 Pages: 97-111
- DOI
  10.1111/gtc.12109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640013, KAKENHI-PROJECT-25670517
[Journal Article] HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism.2014
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Yumimoto, K., Nakayama, K. I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 23 Pages: 16430-41
- DOI
  10.1074/jbc.m113.541490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-24501305, KAKENHI-PUBLICLY-25112517
[Journal Article] Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal2014
- Author(s)
  Kanatsu-Shinohara, M., Onoyama, I., Nakayama, K. I., Shinohara, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 111 Issue: 24 Pages: 8826-8831
- DOI
  10.1073/pnas.1401837111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25221303
[Journal Article] Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development2014
- Author(s)
  Kitagawa, K., Shibata, K., Matsumoto, A., Matsumoto, M., Ohhata, T., Nakayama, K. I., Niida, H., Kitagawa, M.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34 Issue: 14 Pages: 2732-2744
- DOI
  10.1128/mcb.01549-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-24570151, KAKENHI-PUBLICLY-25112508
[Journal Article] Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia2014
- Author(s)
  Hashimoto Y., Shirane M., Matsuzaki F., Saita S., Ohnishi T., Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670517
[Journal Article] Role of Fbxw7 in maintenance of normal stem cells and cancer-initiating cells2014
- Author(s)
  Takeishi S., Nakayama KI.
- Journal Title
  
  Br. J. Cancer
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway2014
- Author(s)
  Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 42 Issue: 15 Pages: 10037-10049
- DOI
  10.1093/nar/gku652
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-26640080, KAKENHI-PUBLICLY-26116721
[Journal Article] SCF-type ubiquitin ligase Fbxw7 negatively regulates spermatogonial stem cell self-renewal2014
- Author(s)
  Kanatsu-Shinohara M., Onoyama I., Nakayama KI., Shinohara T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX242014
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Yumimoto, K., Nakayama, K. I.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 34 Issue: 17 Pages: 3321-3340
- DOI
  10.1128/mcb.00320-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501305, KAKENHI-PUBLICLY-25112517, KAKENHI-PROJECT-25860241, KAKENHI-PROJECT-26640080
[Journal Article] p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling.2014
- Author(s)
  Matsumoto, A., Takeishi, S., Nakayama, K. I.
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 22 Pages: 3429-39
- DOI
  10.1182/blood-2013-10-532390
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Journal Article] F-box and WD repeat domain containing-7 (Fbxw7) targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation2013
- Author(s)
  Yumimoto K., Matsumoto M., Onoyama I., Imaizumi K., Nakayama KI.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 40 Pages: 28488-502
- DOI
  10.1074/jbc.m113.465179
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PUBLICLY-24116518, KAKENHI-PUBLICLY-25134714, KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-25290078, KAKENHI-PROJECT-25650069, KAKENHI-PROJECT-25860241
[Journal Article] Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.2013
- Author(s)
  Reavie L
- Journal Title
  
  Cancer Cell
  
  Volume: 23 Issue: 3 Pages: 362-375
- DOI
  10.1016/j.ccr.2013.01.025
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-22240038, KAKENHI-PROJECT-24501305
[Journal Article] p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis2013
- Author(s)
  Furutachi S, Matsumoto A, Nakayama K.I, Gotoh Y
- Journal Title
  
  EMBO J.
  
  Volume: 32 Issue: 7 Pages: 970-981
- DOI
  10.1038/emboj.2013.50
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22123003, KAKENHI-PROJECT-25221303
[Journal Article] Selective escape of proteins from mitochondria during mitophagy2013
- Author(s)
  Saita, et al
- Journal Title
  
  Nature Communications
  
  Volume: 29(web) Issue: 1 Pages: 1410-1423
- DOI
  10.1038/ncomms2400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02843, KAKENHI-PROJECT-20670003, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-22240038, KAKENHI-PROJECT-24501305, KAKENHI-PUBLICLY-23110512
[Journal Article] Selective escape of proteins from the mitochondria during mitophagy2013
- Author(s)
  Saita, S., Shirane, M., Nakayama, K. I.
- Journal Title
  
  Nature Commun.
  
  Volume: 4 Pages: 1410-1410
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes2013
- Author(s)
  Hirano, A., Yumimoto, K., Tsunematsu, R., Matsumoto, M., Oyama, M., Kozuka-Hata, H., Nakagawa, T., Lanjakornsiripan, D., *Nakayama, K. I., Fukada, Y. (Co-corresponding authors)
- Journal Title
  
  Cell
  
  Volume: 152 Pages: 1106-1118
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.2013
- Author(s)
  Zhao H
- Journal Title
  
  Cancer Cell
  
  Volume: 24 Issue: 5 Pages: 645-659
- DOI
  10.1016/j.ccr.2013.09.021
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25221303
[Journal Article] Ablation of fbxw7 eliminates leukemia-initiating cells by preventing quiescence.2013
- Author(s)
  Takeishi S
- Journal Title
  
  Cancer Cell
  
  Volume: 23 Issue: 3 Pages: 347-361
- DOI
  10.1016/j.ccr.2013.01.026
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-22240038, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24501305, KAKENHI-PUBLICLY-23130507
[Journal Article] Ablation of fbxw7 eliminates leukemia-initiating cells by preventing quiescence2013
- Author(s)
  Takeishi, S., Matsumoto, A., Onoyama, I., Naka, K., Hirao, A., Nakayama, K. I
- Journal Title
  
  Cancer Cell
  
  Volume: 23 Pages: 347-361
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes2013
- Author(s)
  Arisa Hirano, Kanae Yumimoto, Ryosuke Tsunematsu, Masaki Matsumoto, Masaaki Oyama, Hiroko Kozuka-Hata, Tomoki Nakagawa, Darin Lanjakornsiripan, Keiichi I. Nakayama, and Yoshitaka Fukada
- Journal Title
  
  Cell
  
  Volume: 152 Issue: 5 Pages: 1106-1118
- DOI
  10.1016/j.cell.2013.01.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J08444, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-22240038, KAKENHI-PROJECT-23510254, KAKENHI-PUBLICLY-24116518, KAKENHI-PROJECT-24227001, KAKENHI-PROJECT-24501305, KAKENHI-PUBLICLY-25134714, KAKENHI-PROJECT-25290078, KAKENHI-PUBLICLY-23117513
[Journal Article] Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex2013
- Author(s)
  Yumimoto, K. Muneoka, T. Tsuboi, T. Nakayama, K. I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 45 Pages: 32766-32776
- DOI
  10.1074/jbc.m113.511303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25221303, KAKENHI-PROJECT-25860241
[Journal Article] Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression2013
- Author(s)
  Reavie, L., Buckley, S. M., Loizou, E., Takeishi, S., Aranda-Orgilles, B., Ndiaye-Lobry, D., Abdel-Wahab, O., Ibrahim, S., Nakayama, K. I., Aifantis, I
- Journal Title
  
  Cancer Cell
  
  Volume: 23 Pages: 362-375
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, Herceptin sensitivity and tumorigenesis2012
- Author(s)
  Chan CH.,Li CF., Yang WL., Gao Y., Lee SW., Feng Z., Huang HY., Tsai KKC., Flores LG., Shao Y., Hazle JD., Yu D., Wei W., Sarbassov D., Hung MC., Nakayama KL., Lin HK.
- Journal Title
  
  Cell
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis2012
- Author(s)
  Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I., Lin, H. K.
- Journal Title
  
  Cell
  
  Volume: 149 Pages: 1098-1111
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] UPS delivers pluripotency2012
- Author(s)
  Okita, Y., Nakayama, K. I.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 11 Pages: 728-730
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, Herceptin sensitivity and tumorigenesis2012
- Author(s)
  Chan CH., Li CF., Yang WL., Gao Y., Lee SW., Feng Z., Huang HY., Tsai KKC., Flores LG., Shao Y., Hazle JD., Yu D., Wei W., Sarbassov D., Hung MC., Nakayama KL., Lin HK.
- Journal Title
  
  Cell
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway2012
- Author(s)
  Nishiyama M, Skoultchi AI, Nakayama KI
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32 Issue: 2 Pages: 501-512
- DOI
  10.1128/mcb.06409-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22680061, KAKENHI-PROJECT-24501305
[Journal Article] Identification of CHD7(S) as a novel splicing variant of CHD7 with functions similar and antagonistic to those of the full-length CHD7(L).2012
- Author(s)
  Kita, Y., Nishiyama, M., Nakayama, K. I.
- Journal Title
  
  Genes Cells
  
  Volume: 17 Issue: 7 Pages: 536-547
- DOI
  10.1111/j.1365-2443.2012.01606.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501305
[Journal Article] The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo2011
- Author(s)
  Moroishi T., Nishiyama M., Takeda Y., Iwai K., Nakayama KI.
- Journal Title
  
  Cell Metabolism
  
  Volume: 14 Issue: 3 Pages: 339-351
- DOI
  10.1016/j.cmet.2011.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-22240038, KAKENHI-PROJECT-22680061
[Journal Article] Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation2011
- Author(s)
  Matsuzaki, F., Shirane, M., Matsumoto, M., Nakayama, K. I.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 22 Pages: 4602-4620
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2011
- Author(s)
  Onoyama, I., Suzuki, A., Matsumoto A., Tomita K., Katagiri, H., Oike Y., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip12011
- Author(s)
  Katagiri K, Ueda Y, Tomiyama T, Yasuda K, Toda Y, Ikehara S, Nakayama KI, Kinashi T
- Journal Title
  
  Immunity
  
  Volume: 34(1) Pages: 24-38
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Spyracopoulos, L., Leng, R. P.: UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p532011
- Author(s)
  Wu, H., Pomeroy, S. L., Ferreira, M., Teider, N., Mariani, J., Nakayama, K. I., Hatakeyama, S.
- Journal Title
  
  Nature Med.
  
  Volume: 17 Pages: 347-355
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip12011
- Author(s)
  Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K. I., Kinashi, T.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 24-38
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.2011
- Author(s)
  Onoyama, I., Suzuki, A., Matsumoto, A., Tomita, K., Katagiri, H., Oike, Y., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 121 Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction2011
- Author(s)
  Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, De Pinho RA, Wei W
- Journal Title
  
  Nature
  
  Volume: 471(7336) Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] p57Kip2 and p27Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc702011
- Author(s)
  Zou, P., Yoshihara, H., Hosokawa, K., Tai, I., Shinmyozu, K., Tsukahara, F., Maru, Y., Nakayama, K., Nakayama, K. I., Suda, T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Pages: 247-261
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Fbxw7 controls lipid metabolism and cell fate decision in the liver in mice2011
- Author(s)
  Onoyama I, Suzuki A, Matsumoto A, Tomita K, Katagiri H, Oike Y, Nakayama K, Nakayama KI
- Journal Title
  
  J Clin Invest
  
  Volume: 121(1) Pages: 342-354
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver. J. Clin. Inves2011
- Author(s)
  Onoyama, I., Suzuki, A., Matsumoto, A., Tomita, K., Katagiri, H., Oike, Y., Nakayama, K., Nakayama, K. I
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 121 Pages: 342-354
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo2011
- Author(s)
  Moroishi, T., Nishiyama, M., Takeda, Y., Iwai, K., Nakayama, K. I.
- Journal Title
  
  Cell Metab.
  
  Volume: 14 Pages: 339-351
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] p57 is required for quiescence and maintenance of adult hematopoietic stem cells2011
- Author(s)
  Matsumoto A, et al
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Issue: 3 Pages: 262-271
- DOI
  10.1016/j.stem.2011.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00843, KAKENHI-PLANNED-19057011, KAKENHI-PLANNED-22130003
[Journal Article] Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7&alpha ; overexpression2011
- Author(s)
  Iriuchishima H, Takubo K, Matsuoka S, Onoyama I, Nakayama KI, Nojima Y, Suda T
- Journal Title
  
  Blood
  
  Volume: 117(8) Pages: 2373-7
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Fbxw7-dependent degradation of Notch is required for control of stemness and neuronal-glial differentiation in neural stem cells.2011
- Author(s)
  Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI.
- Journal Title
  
  J Biol Chem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025025
[Journal Article] SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.2011
- Author(s)
  Inuzuka, H., Shaik, S., Onoyama I., Gao, D., Tseng, A., Maser, R.S., Zhai, B., Wan, L., Gutierrez, A., Lau A.W., Xiao, Y., Christie, A.L., Aster J., Settleman J., Gygi, S.P., Kung, A.L., Look, T., Nakayama, K.I., DePinho, R.A., Wei, W.
- Journal Title
  
  Nature
  
  Volume: 471 Pages: 104-109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquity lation and destruction.2011
- Author(s)
  Inuzuka, H., Shaik, S., Onoyama, I., Gao, D., Tseng, A., Maser, R.S., Zhai, B., Wan, L., Gutierrez, A., Lau, A.W., Xiao, Y., Christie, A.L., Aster, J., Settleman, J., Gygi, S.P., Kung, A.L., Look, T., Nakayama, K.I., DePinho, R.A., Wei, W.
- Journal Title
  
  Nature
  
  Volume: 471 Pages: 104-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p532011
- Author(s)
  Wu H, Pomeroy SL, Ferreira M, Teider N, Mariani J, Nakayama KI, Hatakeyama S, Tron VA, Saltibus LF, Spyracopoulos L, Leng RP
- Journal Title
  
  Nat Med
  
  Volume: 17(3) Pages: 347-55
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] p57 is required for quiescence and maintenance of adult hematopoietic stem cells2011
- Author(s)
  Matsumoto, A., Takeishi, S., Kanie, T., Susaki, E., Onoyama, I., Tateishi, Y., Nakayama, K., Nakayama, K. I.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Pages: 262-271
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Proteome of ubiquitin/MVB pathway : possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation2011
- Author(s)
  Tachiyama R, Ishikawa D, Matsumoto M, Nakayama KI, Yoshimori T, Yokota S, Himeno M, Tanaka Y, Fujita H.
- Journal Title
  
  Genes Cells
  
  Volume: 16 Pages: 448-466
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025025
[Journal Article] SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction2011
- Author(s)
  Inuzuka, H., Shaik, S., Onoyama, I., Gao, D., Tseng, A., Maser, R. S., Zhai, B., Wan, L., Gutierrez, A., Lau, A. W., Xiao, Y., Christie, A. L., Aster, J., Settleman, J., Gygi, S. P., Kung, A. L., Look, T., Nakayama, K. I., DePinho, R. A., Wei, W.
- Journal Title
  
  Nature
  
  Volume: 471 Pages: 104-109
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] TRIM8 modulates STAT3 activity through negative regulation of PIAS32010
- Author(s)
  Okumura F, Matsunaga Y, Katayama Y, Nakayama KI, Hatakeyama S
- Journal Title
  
  J Cell Sci
  
  Volume: 123 Pages: 2238-2245
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice2010
- Author(s)
  Wang, H., Bauzon, F., Ji, P., Xu, X., Sun, D., Locker, J., Sellers, R.S., Nakayama, K., Nakayama, K.I., Cobrinik, D., Zhu, L.
- Journal Title
  
  Nature Genet 42
  
  Pages: 83-88
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] KDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development2010
- Author(s)
  Tsukada, Y., Ishitani, T., Nakayama, K.I.
- Journal Title
  
  Genes & Development 24
  
  Pages: 432-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity.2010
- Author(s)
  Susaki, E., Kaneko-Oshikawa, C., Miyata, K., Tabata, M., Yamada T., Oike Y., Katagiri, H., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 15538-15547
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003
[Journal Article] KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.2010
- Author(s)
  Tsukada, Y., Ishitani, T., Nakayama, K.I.
- Journal Title
  
  Genes Dev 24
  
  Pages: 432-437
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis2010
- Author(s)
  Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK
- Journal Title
  
  Nature Cell Biol
  
  Volume: 12 Pages: 457-467
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development2010
- Author(s)
  Tsukada, Y., Ishitani, T., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 24
  
  Pages: 432-437
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity2010
- Author(s)
  Susaki, E., Kaneko-Oshikawa, C., Miyata, K., Tabata, M., Yamada, T., Oike, Y., Katagiri, H., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 15538-15547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.2010
- Author(s)
  Chan, C.H., Lee, S.W., Li, C.F., Wang, J., Yang, W.L., Wu, C.Y., Wu, J., Nakayama, K.I., Kang, H.Y., Huang, H.Y., Hung, M.C., Pandolfi, P.P., Lin, H.K.
- Journal Title
  
  Nature Cell Biol.
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc42010
- Author(s)
  Benirschke RC, Thompson JR, Nomine Y, Wasielewski E, Juranic N, Macura S, Hatakeyama S, Nakayama KI, Botuyan MV, Mer G
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 955-965
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.2010
- Author(s)
  Lin, H.K., Chen, Z., Wang, G., Nardella, C., Lee, S.W., Chan, C.H., Yang, W.L., Wang, J., Egia, A., Nakayama, K.I., Cordon-Cardo, C., Teruya-Feldstein, J., Pandolfi, P.P.
- Journal Title
  
  Nature 464
  
  Pages: 374-379
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer : clinical significance2010
- Author(s)
  Iwatsuki M, Mimori K, Ishii H, Yokobori T, Takatsuno Y, Sato T, Toh H, Onoyama I, Nakayama KI, Baba H, Mori M
- Journal Title
  
  Int J Cancer
  
  Volume: 126 Pages: 1828-1837
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Fbxo45, a novel ubiquitin ligase, regulates synaptic activity2010
- Author(s)
  Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 3840-3849
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H32010
- Author(s)
  Hatano A, Matsumoto M, Higashinakagawa T, Nakayama KI
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397 Pages: 93-99
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis2010
- Author(s)
  Old JB, Kratzat S, Hoellein A, Graf S, Nilsson JA, Nilsson L, Nakayama KI, Peschel C, Clevel, JL, Keller UB
- Journal Title
  
  Mol Cancer Res
  
  Volume: 8 Pages: 353-362
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression : role of protein phosphatases2010
- Author(s)
  Ma H, Yu L, Byra EA, Hu N, Kitagawa K, Nakayama KI, Kawamoto T, Ren J
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 49 Pages: 322-329
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis2010
- Author(s)
  Chan, C.H., Lee, S.W., Li, C.F., Wang, J., Yang, W.L., Wu, C.Y., Wu, J., Nakayama, K.I., Kang, H.Y., Huang, H.Y., Hung, M.C., Pandolfi, P.P., Lin, H.K.
- Journal Title
  
  Nature Cell Biol. (in press)
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress2010
- Author(s)
  Hayakawa H, Fujikane A, Ito R, Matsumoto M, Nakayama KI, Sekiguchi M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 403(2) Pages: 220-4
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence2010
- Author(s)
  Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP
- Journal Title
  
  Nature
  
  Volume: 464 Pages: 374-379
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis2010
- Author(s)
  Chan, C. H., Lee, S. W., Li, C. F., Wang, J., Yang, W. L., Wu, C. Y., Wu, J., Nakayama, K. I., Kang, H. Y., Huang, H. Y., Hung, M. C., Pandolfi, P. P., Lin, H. K.
- Journal Title
  
  Nature Cell Biol.
  
  Volume: 12 Pages: 457-467
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity2010
- Author(s)
  Susaki E, Kaneko-Oshikawa C, Miyata K, Tabata M, Yamada T, Oike Y, Katagiri H, Nakayama KI
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 15538-15547
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis2010
- Author(s)
  Shimizu T, Ishikawa T, Sugihara E, Kuninaka S, Miyamoto T, Mabuchi Y, Matsuzaki Y, Tsunoda T, Miya F, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Kawai A, Ichikawa H, Hasegawa T, Okada S, Ito T, Ikeda Y, Suda T, Saya H
- Journal Title
  
  Oncogene
  
  Volume: 29(42) Pages: 5687-99
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors2010
- Author(s)
  Fujii M, Kanematsu T, Ishibashi H, Fukami K, Takenawa T, Nakayama KI, Moss SJ, Nabekura J, Hirata M
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 4837-4846
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] In vitro histone demethylase assay2010
- Author(s)
  Tsukada Y, Nakayama KI
- Journal Title
  
  Cold Spring Harb Protoc
  
  Volume: 2010(10)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] KDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development2010
- Author(s)
  Tsukada, Y., Ishitani, T., Nakayama, K.I.
- Journal Title
  
  Genes & Development 24
  
  Pages: 432-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] KDM7 is a dual demethylase for histone H3 lysines 9 and 27 and functions in brain development2010
- Author(s)
  Tsukada, Y., Ishitani, T., Nakayama, K. I.
- Journal Title
  
  Genes Dev.
  
  Volume: 24 Pages: 432-437
- Data Source
  KAKENHI-PROJECT-22240038
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice2010
- Author(s)
  Wang H., Bauzon F., Ji P., Xu X., Sun D., Locker J., Sellers R.S., Nakayama K, Nakayama KI., Cobrinik D., and Zhu L
- Journal Title
  
  Nat Genet
  
  Volume: 42 Issue: 1 Pages: 83-88
- DOI
  10.1038/ng.498
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057011
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/-mice.2010
- Author(s)
  Wang, H., Bauzon, F., Ji, P., Xu, X., Sun, D., Locker, J., Sellers, R.S., Nakayama, K., Nakayama, K.I., Cobrinik, D., Zhu, L.
- Journal Title
  
  Nature Genet. 42
  
  Pages: 83-88
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Nedd4-interacting protein 2, a short half-life membrane protein degraded in lysosomes, negatively controls down-regulation of connexin432010
- Author(s)
  Ohzono C, Etoh S, Matsumoto M, Nakayama KI, Hirota Y, Tanaka Y, Fujita H
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 33 Pages: 951-957
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Comparative Analysis of Human Src-family Kinase Substrate Specificity in vitro2010
- Author(s)
  Takeda H, Kawamura Y, Miura A, Mori M, Wakamatsu A, Yamamoto JI, Isogai T, Matsumoto M, Nakayama KI, Natsume T, Nomura N, Goshima N
- Journal Title
  
  J Proteome Res
  
  Volume: 9(11) Pages: 5982-93
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence2010
- Author(s)
  Lin, H.K., Chen, Z., Wang, G., Nardella, C., Lee, S.W., Chan, C.H., Yang, W.L., Wang, J., Egia, A., Nakayama, K.I., Cordon-Cardo, C., Teruya-Feldstein, J., Pandolfi, P.P.
- Journal Title
  
  Nature 464
  
  Pages: 374-379
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2010
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development2010
- Author(s)
  Tsukada Y, Ishitani T, Nakayama KI
- Journal Title
  
  Genes Dev
  
  Volume: 24 Pages: 432-437
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] GABA(A) receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice2010
- Author(s)
  Mizokami A, Tanaka H, Ishibashi H, Umebayashi H, Fukami K, Takenawa T, Nakayama KI, Yokoyama T, Nabekura J, Kanematsu T, Hirata M
- Journal Title
  
  J Neurochem
  
  Volume: 114 Pages: 302-310
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Regulation of osteoclast apoptosis by bcl-2 family protein bim and caspase-32010
- Author(s)
  Tanaka S, Wakeyama H, Akiyama T, Takahashi K, Amano H, Nakayama KI, Nakamura K
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 658 Pages: 111-116
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] In Vitro Histone Demethylase Assay2010
- Author(s)
  Yu-ichi Tsukada, Keiichi I.Nakayama
- Journal Title
  
  Cold Spring Harbor Protocols
  
  Volume: VOL.10
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21028015
[Journal Article] Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1^<+/-> mice2010
- Author(s)
  Wang H, Bauzon F, Ji P, Xu X, Sun D, Locker J, Sellers RS, Nakayama K, Nakayama KI, Cobrinik D, Zhu L
- Journal Title
  
  Nature Genet
  
  Volume: 42 Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB2009
- Author(s)
  Lin, H.K., Wang, G., Chen, Z., Teruya-Feldstein, J., Liu, Y., Chan, C.H., Yang, W.L., Erdjument-Bromage, H., Nakayama, K.I., Nimer, S., Tempst, P., Pandolfi, P.P.
- Journal Title
  
  Nature Cell Biol 11
  
  Pages: 420-432
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein(VAP)2009
- Author(s)
  Saita, S., Shirane, M., Natume, T., Iemura, S., Nakayama, K.I.
- Journal Title
  
  Journal of Biological Chemistry 284
  
  Pages: 13766-13777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein (VAP)2009
- Author(s)
  Saita, S., et.al., and Nakayama, K. I.
- Journal Title
  
  J. Biol. Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.2009
- Author(s)
  Endo, A., Matsumoto, M., Inada, T., Yamamoto, A., Nakayama, K.I., Kitamura, N., Komada, M.
- Journal Title
  
  J.Cell Sci. 122
  
  Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025025
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein (VAP)2009
- Author(s)
  Saita, S., et al., Nakayama, K. I.
- Journal Title
  
  J. Biol. Chem. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein(VAP)2009
- Author(s)
  Saita, S., Shirane, M., Nakayama, K.I.
- Journal Title
  
  J.Biol. Chem. 284
  
  Pages: 13766-13777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022030
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.2009
- Author(s)
  Nishiyama, M., Oshikawa, K., Tsukada, Y., Nakagawa, T., Iemura, S., Natsume, T., Fan, Y., Kikuchi, A., Skoultchi, A.I., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 172-182
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis2009
- Author(s)
  Nishiyama, M., et.al., and Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 172-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embrvogenesis2009
- Author(s)
  Nishiyama, M., et.al., and Nakayama, K.I
- Journal Title
  
  Nature Cell Biol 11
  
  Pages: 172-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022030
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model2009
- Author(s)
  Susaki, E., Nakayama, K., Yamasaki, L., Nakayama, K.I.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 106
  
  Pages: 5192-5197
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis2009
- Author(s)
  Nishiyama, M., et al., Nakayama, K. I.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 172-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model2009
- Author(s)
  Susaki, E., Nakayama, K., Yamasaki, L, and Nakayama, K.I.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis2009
- Author(s)
  Nishiyama, M., Oshikawa, K., Tsukada, Y., Nakagawa, T., Iemura, S., Natsume, T., Fan, Y., Kikuchi, A., Skoultchi, A.I., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 172-182
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model2009
- Author(s)
  Susaki E, Nakayama K, Yamasaki L, Nakayama KI
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 106 Issue: 13 Pages: 5192-7
- DOI
  10.1073/pnas.0811712106
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057011
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated nrotein(VAP)2009
- Author(s)
  Saita, S., Shirane, M., and Nakayama, K.I
- Journal Title
  
  J. Biol. Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022030
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development2009
- Author(s)
  Saiga, T., Fukuda, T., Matsumoto, M., Tada, H., Okano, H.O., Okano, H., Nakayama, K.I.
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development2009
- Author(s)
  Saiga, T., Fukuda, T., Matsumoto, M., Tada, H., Okano, H.O., Okano, H., Nakayama, K.I.
- Journal Title
  
  Molecular and Cellular Biology 29
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis2009
- Author(s)
  Nishiyama, M., et.al., and Nakayama. K.I.
- Journal Title
  
  Nature Cell Biol 11
  
  Pages: 172-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20054014
[Journal Article] Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development2009
- Author(s)
  Saiga, T., Fukuda, T., Matsumoto, M., Tada, H., Okano, Okano, H., Nakayama KI.
- Journal Title
  
  Mol.Cell.Biol. 29
  
  Pages: 3529-3543
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025025
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein (VAP)2009
- Author(s)
  Saita, S., Shirane, M., and Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20054014
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein (VAP)2009
- Author(s)
  Saita, S., Shirane, M., Nakayama, K.I.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 13766-13777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20054014
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model2009
- Author(s)
  Susaki, E., Nakayama, K., Yamasaki, L, Nakayama, K. I.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Large-scale proteomic analysis of tyrosine phosphorylation induced by TCR or BCR activation reveals new signaling pathways.2009
- Author(s)
  Matsumoto, M., Oyamada, K., Takahashi, H., Sato, T., Hatakeyama, S., Nakayama, K.I.
- Journal Title
  
  Proteomics 9
  
  Pages: 3549-3563
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025025
[Journal Article] Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.2009
- Author(s)
  Lin, H.K., Wang, G., Chen, Z., Teruya-Feldstein, J., Liu, Y., Chan, C.H., Yang, W.L., Erdjument-Bromage, H., Nakayama, K.I., Nimer, S., Tempst, P., Pandolfi, P.P.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 420-432
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model.2009
- Author(s)
  Susaki, E., Nakayama, K., Yamasaki, L., Nakayama, K.I.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 106
  
  Pages: 5192-5197
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Promotion of neurite extension by protrudin requires its interaction with VAMP-associated protein (VAP)2009
- Author(s)
  Saita, S., Shirane, M., Natume, T., Iemura, S., Nakayama, K.I.
- Journal Title
  
  Journal of Biological Chemistry 284
  
  Pages: 13766-13777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Dynamic regulation of ubiquitination and deubiquitination at the central spindle during cytokinesis.2008
- Author(s)
  Mukai, A.・Mizuno, E.・Kobayashi, K.・Matsumoto, M.・Nakayama, K. I.・Kitamura, N.・Komada, M.
- Journal Title
  
  J. Cell Science (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Blue light-induced autophosphorylation of phototropin is a primary step for signaling.2008
- Author(s)
  Inoue, S.・Kinshita, T.・Matsumoto, M.・Nakayama, K.L.・Doi, M.・Shimazaki, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023017
[Journal Article] Dynamic regulation of ubiquitination and deubiquitination at the central spindle during cytokinesis.2008
- Author(s)
  Mukai, A.・Mizuno, E.・Kobayashi, K.・Matsumoto, M.・Nakayama, K.I.・Kitamura, N.・Komada, M.
- Journal Title
  
  J. Cell Science (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023017
[Journal Article] Mice lacking the schizophrenia-associated protein FEZ1 manifest hyper- activity and enhanced responsive- ness to psychostimulants2008
- Author(s)
  Sakae N., Yamasaki N., Kitaichi K., Fukuda T., Yamada M., Yoshikawa H., Hiranita T., Tatsumi Y., Kira J., Yamamoto T., Miyakawa T., and Nakayama KI
- Journal Title
  
  Hum Mol Genet
  
  Volume: 17 Issue: 20 Pages: 3191-203
- DOI
  10.1093/hmg/ddn215
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19057011
[Journal Article] Blue light-induced autophosphorylation of phototropin is a primary step for signaling.2008
- Author(s)
  Inoue, S.・Kinshita, T.・Matsumoto, M.・Nakayama, K. L.・Doi, M.・Shimazaki, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse2008
- Author(s)
  Shirane M., Ogawa M., Motoyama J., Nakayama KI.
- Journal Title
  
  Genes Cells 13
  
  Pages: 635-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20054014
[Journal Article] Regulation of apoptosis and neurite extension by FKBP38 is reauired for neural tube formation in the mouse2008
- Author(s)
  Shirane M., Ogawa M., Motoyama J., Nakayama KI
- Journal Title
  
  Genes Cells 13
  
  Pages: 635-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022030
[Journal Article] Cyclin D2 translocates p27 out of the nucleus and promotes its degradation at the G0-G1 transition.2007
- Author(s)
  Susaki, E., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Mol. Cell. Biol. (印刷中)
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Cyclin D2 translocates p27 out of the nucleus and promotes its degradation at the G0-G1 transition.2007
- Author(s)
  Susaki, E., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Mol. Cell. Biol. (in press)
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis2007
- Author(s)
  Onoyama, I., Tsunematsu, R., Matsumoto, A., Kimura, T., de Alboran, I.M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  J. Exp. Med. 204
  
  Pages: 2875-2888
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.2007
- Author(s)
  Onoyama, I., Tsunematsu, R., Matsumoto, A., Kimura, T., de Alboran, I.M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  J. Exp. Med. 204
  
  Pages: 2875-2888
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner.2006
- Author(s)
  Matsumoto A, Onoyama I, Nakayama KI.
- Journal Title
  
  Biochem Biophys Res Commun. 350
  
  Pages: 114-119
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.2006
- Author(s)
  Fujii, Y., Yadam M., Nishiyama, M., et al., Nakayama, K.I.
- Journal Title
  
  Cancer Sci. 97
  
  Pages: 729-736
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking2006
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Fbxw8 is essential for Cull-Cul7 complex formation and for placental development.2006
- Author(s)
  Tsunematsu R, Nishiyama M, Kotoshiba S, Saiga T, Kamura T, Nakayama KI.
- Journal Title
  
  Mol Cell Biol. 26
  
  Pages: 6157-6169
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking2006
- Author(s)
  Shirane, M., Nakayama K.-i.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-18050027
[Journal Article] Mitogenic signalling and the p16^<INK4a>-Rb pathway cooperate to enforce irreversible cellular senescence.2006
- Author(s)
  Tanahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking2006
- Author(s)
  Shirane, M., Nakayama, K.-i.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-18022030
[Journal Article] Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence.2006
- Author(s)
  Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence2006
- Author(s)
  Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Geminin is essential for the development of preimplantation mouse embryos.2006
- Author(s)
  Hara, K., Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1281-1293
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking.2006
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Fbxw8 is essential for Cull-Cul7 complex formation and for placental development.2006
- Author(s)
  Tsunematsu, R., Nishiyama, M., Kotoshiba, S., Saiga, T., Kamura, T., Nakayama, K.I.
- Journal Title
  
  Mol. Cell. Biol. 26
  
  Pages: 6157-6169
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking2006
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Ubiquitin ligases: cell-cycle control and cancer2006
- Author(s)
  Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Nature Rev. Cancer 6
  
  Pages: 369-381
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking.2006
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.2006
- Author(s)
  Fujii, Y., Yada, M., Nishiyama, M., et al., Nakayama, K.I.
- Journal Title
  
  Cancer Sci. 97
  
  Pages: 729-736
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Ubiquitin ligases : cell-cycle control and cancer.2006
- Author(s)
  Nakayama K.I., Nakayama, K.
- Journal Title
  
  Nature Rev. Cancer 6
  
  Pages: 369-381
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Geminin is essential for the development of preimplantation mouse embryos.2006
- Author(s)
  Hara K, Nakayama KI, Nakayama K.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1281-1293
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Mitogenic signalling and the p16^<INK4a>-Rb pathway cooperate to enforce irreversible cellular senescence.2006
- Author(s)
  Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 1291-1297
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Geminin is essential for the development of preimplantation mouse embryos.2006
- Author(s)
  Hara, K., Nakayama, K.I., Nakayama, K.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1281-1293
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Fbxw8 is essential for Cull-Cul7 complex formation and for placental development.2006
- Author(s)
  Tsunematsu, R., Nishiyama, M., Kotoshiba, S., Saiga, T., Kamura, T., Nakayama, K.I.
- Journal Title
  
  Mol. Cell. Biol. 26
  
  Pages: 6157-6169
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking.2006
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Protrudin induces neurite formation by directional membrane trafficking2006
- Author(s)
  Shirane M, Nakayama KI.
- Journal Title
  
  Science 314
  
  Pages: 818-821
- Data Source
  KAKENHI-PROJECT-18016024
[Journal Article] Title : Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein (PML).2005
- Author(s)
  Takahashi.H., Hatakeyama, S., Saitoh H., Nakayama, K-i.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 5611-5621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice.2005
- Author(s)
  Uchida, T., et al., Nakayama, K.I., Kasuga, M.
- Journal Title
  
  Nature Med. 11
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.2005
- Author(s)
  Jiang H., et al., Nakayama, K.I., Desiderio S.
- Journal Title
  
  Mol.Cell 18
  
  Pages: 699-709
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Mammalian E4 is required for cardiac development and maintenance o the nervous system.2005
- Author(s)
  Kaneko-Oshikawa, C., Nakagawa, T., Yamada, M., Yoshikawa, H., Matsumoto, M., Yada, M., Hatakeyama S., Nakayama, K., Nakayama, K-i.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 10953-10964
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice.2005
- Author(s)
  Uchida, T., et al., Nakayama, K.I., Kasuga, M.
- Journal Title
  
  Nature Med. 11
  
  Pages: 175-182
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Mammalian E4 is required for cardiac development and maintenance of the nervous system.2005
- Author(s)
  Kaneko-Oshikawa, C., et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 10953-10964
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Targeted destruction of c-Myc by an engineered ubiquitin ligase suppresses cell transformation and tumor formation.2005
- Author(s)
  Hatakeyama S., Watanabe, M., Fujii, Y., Nakayama, K-i.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 7874-7879
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Cell surface expression of CD147/emmprin is regulated by cyclophilin 60.2005
- Author(s)
  Pushkarsky, T., Yurchenko, V., Vanpouille, C., Brichacek, B., Vaisman, I., Hatakeyama, S., Nakayama, K.I., Sherry, B., Bukrinsky M.I.
- Journal Title
  
  J.Bio.Chem. 280
  
  Pages: 27866-27871
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle.2005
- Author(s)
  Jiang H., et al., Nakayama, K.I., Desiderio S.
- Journal Title
  
  Mol. Cell 18
  
  Pages: 699-709
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 Phase.2005
- Author(s)
  Kotoshiba, S., et al., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 17674-17700
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Role of serine-10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine-10 mutation.2005
- Author(s)
  Kotake, Y., et al., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 1095-1102
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.2005
- Author(s)
  Hara, T., et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 9292-9303
- Data Source
  KAKENHI-PROJECT-17107004
[Journal Article] Role of serine-10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine-10 mutation.2005
- Author(s)
  Kotake, Y., et al., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 1095-1102
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Large-scale analysis of the human ubiquitin-related proteome.2005
- Author(s)
  Matsumoto, M., Hatakeyama, S., Oyamada, K., Oda, Y., Nishimura, T., Nakayama, K-i.
- Journal Title
  
  Proteomics 5
  
  Pages: 4145-4151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Mammalian E4 is required for cardiac development and maintenance of the nervous system.2005
- Author(s)
  Kaneko-Oshikawa, C., et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 10953-10964
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Mapping of ubiquitination sites on target proteins.2005
- Author(s)
  Hatakeyama, S., Matsumoto, M., Nakayama, K-i.
- Journal Title
  
  Methods Enzymol. 399
  
  Pages: 277-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 Phase.2005
- Author(s)
  Kotoshiba, S., et al., Nakayama, K.I.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 17674-17700
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.2005
- Author(s)
  Hara, T., et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 25
  
  Pages: 9292-9303
- Data Source
  KAKENHI-PROJECT-17013067
[Journal Article] Ubiquitylation and degradation of polo-like kinase SNK by hVPS18, a RING-H2 type ubiquitin ligase.2005
- Author(s)
  Yogosawa, S., Hatakeyama S., Nakayama, K-i., Miyoshi, H., Kohsaka, S., Akazawa, C.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 41619-41627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.2004
- Author(s)
  Urushitani, M., Kurisu J., Tateno, M., Hatakeyama S., Nakayama, K-i., Kato, S., Takahashi, R.
- Journal Title
  
  J.Neurochem. 90
  
  Pages: 231-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.2004
- Author(s)
  Hatakeyama S., Matsumoto, M.Kamura, T., Murayama, M., Du-Hua Chui, D.-H., Planel, E., Takahashi, R., Nakayama, K-i., Takashima, A.
- Journal Title
  
  J.Neurochem. 91
  
  Pages: 299-307
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto M., Yada, M., Hatakeyama, S., Ishimoto H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M., K-i.Nakayama.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al.Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Phosphorylation- dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K.et al., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 651-672
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27^<Kip1> at G1 phase.2004
- Author(s)
  Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] SUMO-1 modification of the synergy control motif of Ad4BP/SF-1 regulates synergistic transcription between Ad4BP/SF-1 and Sox9.2004
- Author(s)
  Komatsu, T., Mizusaki, H., Mukai, T., Ogawa, H., Baba, D., Shirakawa, M., Hatakeyama, S., Nakayama K-i., Yamamoto H., Kikuchi, A., Morohashi, K.
- Journal Title
  
  Mol Endocronol. 18
  
  Pages: 2451-2462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.2004
- Author(s)
  Okumura, F., Hatakeyama S., Matsumoto, M., Kamura, T., Nakayama, K-i.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 53533-53543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis.2004
- Author(s)
  Nakayama K., Nagahama, H., Minamishima, Y.A., Miyake, S., Ishida, N., Hatakeyama, S., Iemura, S., Natsume, T., Nakayama, K-i.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K.et al., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Early embryonic death in mice lacking the β-catenin-binding protein Duplin.2004
- Author(s)
  Nishiyama, K.et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 8386-8394
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M., Hatakeyama S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura F., Nakayama, K., Nakayama, K-i.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27^<Kip1> at G1 phase.2004
- Author(s)
  Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones.2004
- Author(s)
  Hatakeyama S., Matsumoto, M., Yada, M., Keiichi I., Nakayama, K-i.
- Journal Title
  
  Genes Cells 9
  
  Pages: 533-548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.2004
- Author(s)
  Tsunematsu, R., Nakayama, K., Oike, Y, Nishiyama, M., Ishida, N.Hatakeyama, S., Bessho, B., Kageyama, R., Suda, T., Nakayama, K-i.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 9417-9423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Subcellular expression of autoimmune regulator (AIRE) is organized in a spatiotemporal manner.2004
- Author(s)
  Akiyoshi, H., Hatakeyama, S., Pitkanen J., Mouri, Y., Dougcas, V., Kudoh, J., Tsurugaya, K., Uchida, D., Matsushima, A., Oshikawa, K., Nakayama, K-i., Shimizu N., Peterson, P., Matsumoto, M.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 33984-33991
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Early embryonic death in mice lacking the β-catenin-binding protein Duplin.2004
- Author(s)
  Nishiyama, K.et al., Nakayama, K.I.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 8386-8394
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M., et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis.2004
- Author(s)
  Nakayama, K.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis.2004
- Author(s)
  Nakayama K.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16659104
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K.et al., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M., Yada, M., Hatakeyama, S., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K., Nagahama, H., Minamishima, Y.A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., Iemura, S., Natsume, T., Nakayama, K.I.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K., Nagahama, H., Minamishima, Y.A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., lemura, S., Natsume, T., Nakayama, K.I.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] AIRE, a Protein Responsible for Autoimmunity, Functions as an E3 Ubiquitin Ligase.2004
- Author(s)
  Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J, Shimizu, N., Doucas, V., Nakayama KI., Kuroda, N., Matsumoto, M.
- Journal Title
  
  J.Exp.Med. 199
  
  Pages: 167-172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Skp2-Mediated Degradation of p27 Regulates Progression into Mitosis.2004
- Author(s)
  Nakayama, K.
- Journal Title
  
  Dev.Cell 6
  
  Pages: 661-672
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27^<Kip1> at G1 phase.2004
- Author(s)
  Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama S., Yoshida, M., Nakayama, K., Nakayama, K-i.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300093
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Phosphorylation-dependent degradiation of c-Myc is mediated by the F-box protein Fbw7.2004
- Author(s)
  Yada, M.et al., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 2116-2125
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Skp2-mediated degradation of p27 regulates progression into mitosis.2004
- Author(s)
  Nakayama, K., et al.
- Journal Title
  
  Dev. Cell 6
  
  Pages: 661-672
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1229-1235
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.2004
- Author(s)
  Kamura, T.et al., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 18
  
  Pages: 3055-3065
- Data Source
  KAKENHI-PROJECT-13043039
[Journal Article] Impaired degradation of inhibitory subunit of NF-KB (IKB) and 3- catenin as a result of targeted disruption of the p-TrCP1 gene.2003
- Author(s)
  Nakayama, K., Hatakeyama, S., Maruyama, S., Kikuchi, A., Onoe, K., Good, R.A., Nakayama, K.I.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 100
  
  Pages: 8752-8757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Degradation of p57^<Kip2> mediated by SCF^<skp2>-dependent ubiquitylation.2003
- Author(s)
  Kamura, T., Hara, T., Kotoshiba, S., Yada, M., Ishida, N., Imaki, H., Hatakeyama, S., Nakayama, K., Nakayama, K.I.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 100
  
  Pages: 10231-10236
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.2003
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 5
  
  Pages: 28-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.2003
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 5
  
  Pages: 28-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Journal Article] Inherent calcineurin inhibitor FKBP38 targets BcI-2 to mitochondria and inhibits apoptosis.2003
- Author(s)
  Shirane, M., Nakayama, K.I.
- Journal Title
  
  Nature Cell Biol. 5
  
  Pages: 28-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta.2002
- Author(s)
  Miyamoto, A.et al., Nakayama, K.I.
- Journal Title
  
  Nature 416
  
  Pages: 865-869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Co.2002
- Author(s)
  Miyamoto, A., Nakayama, K., Imaki, H., Hirose, S., Jiang, Y., Abe, M., Tsukiyama, T., Nagahama, H., Ohno, S., Hatakeyama, S., Nakayama, K.I.
- Journal Title
  
  Nature 416
  
  Pages: 865-869
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Targeted disruption of Skp2 results in accumulation of cyclin E and p27^<kip1>, polyploidy and centrosome overduplication.2000
- Author(s)
  Nakayama, K., Nagahama, H., Minamishima, Y.A., Matsumoto, M., Nakamichi, I., Kitagawa, K., Shirane, M., Tsunematsu, R., Tsukiyama, T., Ishida, N., Kitagawa, M., Nakayama, K.I., Hatakeyama, S.
- Journal Title
  
  EMBO J. 19
  
  Pages: 2069-2081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication.2000
- Author(s)
  Nakayama, K.et al., Hatakeyama, S.
- Journal Title
  
  EMBO J. 19
  
  Pages: 2069-2081
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] Aberrant cell cycle checkpoint function and early embryonic death in Chk1^<-/-> mice.2000
- Author(s)
  Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y.A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, N., Nakayama, K.I.
- Journal Title
  
  Genes Dev. 14
  
  Pages: 1439-1447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Journal Article] MiR-221 and miR-155 regulate human dendritic cell development, apoptosis and IL-12 production through targeting of p27kip1, KPC1 and SOCS-1
- Author(s)
  Lu C, Huang X, Zhang X, Roensch K, Cao Q, Nakayama KI, Blazar BR, Zeng Y, Zhou X
- Journal Title
  
  Blood
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Fbxw7-dependent degradation of Notch is required for control of stemness and neuronal-glial differentiation in neural stem cells
- Author(s)
  Matsumoto A, Onoyama I, Sunabori, T, Kageyama R, Okano H, Nakayama KI
- Journal Title
  
  J Biol Chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Patent] 相互作用推定方法、相互作用推定装置および相互作用推定プログラム2021
- Inventor(s)
  中山敬一, 清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-091667
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法2019
- Inventor(s)
  中山敬一、清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法2018
- Inventor(s)
  中山敬一、清水秀幸
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-157870
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] ＦＯＸＫ１阻害剤を含有する組成物及びＦＯＸＫ１阻害作用を有する候補物質のスクリーニング方法2018
- Inventor(s)
  中山敬一
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-185599
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H05215
[Patent] 癌の処置のための方法2014
- Inventor(s)
  中山敬一、三森功士
- Industrial Property Rights Holder
  中山敬一、三森功士
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-266001
- Filing Date
  2014-12-26
- Data Source
  KAKENHI-PLANNED-22130003
[Patent] タンパク質の定量方法2009
- Inventor(s)
  中山敬一, 松本雅記
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Number
  2009-169045
- Filing Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-17013067
[Patent] タンパク質の定量方法2009
- Inventor(s)
  中山敬一・松本雅記
- Industrial Property Rights Holder
  国立大学法人九州大学
- Filing Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-22240038
[Patent] タンパク質の定量方法2009
- Inventor(s)
  中山敬一、松本雅記
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Number
  2009-169045
- Filing Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-17013067
[Patent] タンパク質の定量方法2009
- Inventor(s)
  中山敬一, 松本雅記
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Number
  2009-169045
- Filing Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-17107004
[Patent] 抗肥満薬のスクリーニング方法2006
- Inventor(s)
  中山敬一、洲崎悦生
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Number
  2006-160965
- Filing Date
  2006-06-09
- Data Source
  KAKENHI-PROJECT-17013067
[Patent] タンパク質の定量方法2006
- Inventor(s)
  中山敬一、松本雅記
- Industrial Property Rights Holder
  国立大学法人九州大学
- Industrial Property Number
  2009-169045
- Filing Date
  2006-06-09
- Data Source
  KAKENHI-PROJECT-17107004
[Patent] 血糖調節障害の予防・治療剤,及びそれらのスクリーニング方法2004
- Inventor(s)
  中山敬一他3名
- Industrial Property Rights Holder
  神戸大学, 長野上智行
- Industrial Property Number
  2004-037439
- Filing Date
  2004-02-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Patent] 血糖調節障害の予防・治療剤,及びそれらのスクリーニング方法2004
- Inventor(s)
  春日雅人, 中山敬一, 他
- Industrial Property Rights Holder
  神戸大学長野上智行
- Industrial Property Number
  2004-037439
- Filing Date
  2004-02-13
- Data Source
  KAKENHI-PROJECT-12213097
[Patent] 心筋細胞の増殖方法2003
- Inventor(s)
  中山敬一他2名
- Industrial Property Rights Holder
  第一サントリーファーマ株式会社
- Industrial Property Number
  2003-391708
- Filing Date
  2003-11-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370060
[Patent] 新規ユビキチンリガーゼ2002
- Inventor(s)
  中山敬一, 嘉村巧
- Industrial Property Rights Holder
  協和醗酵工業株式会社
- Industrial Property Number
  2002-156257
- Filing Date
  2002-05-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Patent] サイクリンEをユビキチン化分解するユビキチンリガーゼSCF複合体のF-ボックスタンパク2000
- Inventor(s)
  中山敬一他3名
- Industrial Property Rights Holder
  科学技術振興機構
- Industrial Property Number
  2000-036372
- Filing Date
  2000-02-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213097
[Presentation] Life sciences in the near future: Towards an era of data-driven sciences with artificial intelligence2022
- Author(s)
  Nakayama KI, Matsumoto M
- Organizer
  The 30th Hot Spring Harbor International Symposium: New technologies meet Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] これからの生命科学研究：オミクスから人工知能まで2021
- Author(s)
  中山敬一
- Organizer
  東日本研究医養成プログラム　第11回「夏のリトリート」
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん幹細胞の撲滅による新しいがん治療法2021
- Author(s)
  中山敬一
- Organizer
  第一回日本放射線影響学会・若手部会　放射線影響研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 第二のワールブルグ効果：がんにおけるグルタミン由来窒素代謝の変化2021
- Author(s)
  中山敬一
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん幹細胞における細胞周期制御：がん撲滅のための治療標的としての期待2020
- Author(s)
  中山敬一
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 次世代プロテオミクスが拓く医学生物学の新地平：90年来のがんの謎を解く2020
- Author(s)
  中山敬一
- Organizer
  第9回生命医薬情報学連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] グルタミンからの窒素代謝の変化はがんの悪性進化に必須である：”第二のワールブルグ効果”の発見2020
- Author(s)
  中山敬一
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 近未来のがん研究：オミクスと人工知能によるデータドリブン科学の時代.2019
- Author(s)
  中山　敬一
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism: Discovery of the "second" Warburg effect2019
- Author(s)
  Keiichi I. Nakayama
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 次世代プロテオミクスが拓くがん研究の新時代：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] A metabolic shift in nitrogen flux from glutamine contributes to malignant progression of cancer: Discovery of the SECOND Warburg effect.2019
- Author(s)
  Nakayama, K. I., Kodama, M., Matsumoto, M.
- Organizer
  Cell Symposia: Hallmarks of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 次世代プロテオミクスによって明らかとなったがん代謝ダイナミクス：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism: Discovery of the "second" Warburg effect.2019
- Author(s)
  Nakayama, K. I.
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 7th Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん代謝における窒素利用シフト：第二のワールブルグ効果の発見.2019
- Author(s)
  中山　敬一
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Cell cycle regulation in cancer stem cell2018
- Author(s)
  中山　敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06301
[Presentation] 鉄代謝制御を司るユビキチンシステムと疾患2018
- Author(s)
  中山敬一
- Organizer
  第42回鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] グルタミンからの窒素流束の代謝シフトはがん悪性化に必要である：第二のワールブルグ効果の発見2018
- Author(s)
  中山　敬一
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04000
[Presentation] 人工知能を用いたスコアシステムは乳がん患者の予後を正確に予測する2018
- Author(s)
  中山敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] 転移巣にTAMを呼び寄せるメカニズムとそれを阻害する既存薬2018
- Author(s)
  中山敬一
- Organizer
  第16回がんとハイポキシア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] がん幹細胞における細胞周期制御2018
- Author(s)
  中山敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] グルタミンからの窒素流束の代謝シフトはがん悪性化に必要である：第二のワールブルグ効果の発見2018
- Author(s)
  中山　敬一
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06301
[Presentation] グルタミンからの窒素流束の代謝シフトはがん悪性化に必要である：第二のワールブルグ効果の発見2018
- Author(s)
  中山敬一
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Cell cycle regulation in cancer stem cell2018
- Author(s)
  中山　敬一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04000
[Presentation] c-Mycによって統合されるがん代謝ネットワークの全貌2018
- Author(s)
  中山敬一
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05215
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism2017
- Author(s)
  Nakayama Keiichi I.
- Organizer
  The 1st International Symposium for Trans-Omics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Fbxw7 is essential for quiescence and drug resistance in cancer stem cell2017
- Author(s)
  Keiichi I. Nakayama
- Organizer
  Cullin RING ligases and Protein Neddylation: Biology and Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06301
[Presentation] The autism-related gene Chd8 is essential for adipogenesis2017
- Author(s)
  Kita, Y., Nishiyama, M., Katayama, Y., Miyata, K., Oike, Y., Nakayama, K. I.
- Organizer
  11th International Symposium of The Institute Network
- Place of Presentation
  徳島
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] Next-generation proteomics unveils a global landscape of cancer metabolism2017
- Author(s)
  Keiichi I. Nakayama
- Organizer
  The 1st International Symposium for Trans-Omics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06301
[Presentation] ユビキチンリガーゼFBXL5による鉄代謝制御と肝がん抑制2017
- Author(s)
  武藤　義治, 西山　正章, 諸石　寿朗, 中山　敬一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 次世代プロテオミクスによる「第二のワールブルグ効果」の発見2017
- Author(s)
  中山敬一
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06301
[Presentation] Fbxw7 is essential for quiescence and drug resistance in cancer stem cell2017
- Author(s)
  Nakayama Keiichi I.
- Organizer
  Cullin RING ligases and Protein Neddylation: Biology and Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Aberrant REST activation is associated with CHD8 deficiency in autism2017
- Author(s)
  片山　雄太, 西山　正章, 昌子　浩孝, 大川　恭行, 川村　敦生, 佐藤　哲也, 須山　幹太, 内匠　透, 宮川　剛, 中山　敬一
- Organizer
  新学術領域研究（マイクロエンドフェノタイプによる精神病態学の創出）班会議
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] クロマチンリモデリングの異常によって発症するASDの分子病態2017
- Author(s)
  片山　雄太, 西山　正章, 昌子　浩孝, 大川　恭行, 川村　敦生, 佐藤　哲也, 須山　幹太, 内匠　透, 宮川　剛, 中山　敬一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 次世代プロテオミクスによる「第二のワールブルグ効果」の発見2017
- Author(s)
  中山敬一
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] クロマチンリモデリング因子CHD8による幹細胞老化の防止機構の解明2017
- Author(s)
  仁田　暁大, 西山　正章, 武藤　義治, 片山　雄太, 中山　敬一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 自閉症関連因子CHD8はC/EBPβと協調して脂肪分化を制御する2017
- Author(s)
  喜多　泰之, 西山　正章, 片山　雄太, 白根　道子, 中山　敬一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] Large-scale targeted proteomics unveils a global landscape of cancer metabolism2016
- Author(s)
  Keiichi Nakayama
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthrough in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  オアフ、ハワイ
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01291
[Presentation] 発生期におけるクロマチンリモデリング異常は自閉症の原因となる2016
- Author(s)
  片山雄太, 西山正章, 昌子浩孝, 大川恭行, 川村敦生, 佐藤哲也, 須山幹太, 内匠透, 宮川剛, 中山敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-15H01291
[Presentation] クロマチンリモデリング因子CHD8はオリゴデンドロサイトの分化に必須である2016
- Author(s)
  川村　敦生, 西山　正章, 片山　雄太, 中山　敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 発生期におけるクロマチンリモデリング異常は自閉症の原因となる2016
- Author(s)
  片山　雄太, 西山　正章, 昌子　浩孝, 大川　恭行, 川村　敦生, 佐藤　哲也, 須山　幹太, 内匠　透, 宮川　剛, 中山　敬一
- Organizer
  新学術領域研究（生殖細胞のエピゲノムダイナミクスとその制御、ステムセルエイジングから解明する疾患原理）合同若手育成合宿
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 発生期におけるクロマチンリモデリング異常は自閉症の原因となる2016
- Author(s)
  片山　雄太, 西山　正章, 昌子　浩孝, 大川　恭行, 川村　敦生, 佐藤　哲也, 須山　幹太, 内匠　透, 宮川　剛, 中山　敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] クロマチンリモデリングによる幹細胞老化と癌の制御機構解明2016
- Author(s)
  仁田　暁大, 西山　正章, 中山　敬一
- Organizer
  新学術領域研究（幹細胞老化と疾患）若手の会
- Place of Presentation
  熱海
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] Cell cycle regulation in cancer stem cell2016
- Author(s)
  Nakayama, K. I.
- Organizer
  The 47th International Symposium of The Princess Takamatsu Cancer Research Fund: Current status and perspectiveof cancer stem cell research
- Place of Presentation
  東京
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] ユビキチンリガーゼFbxw7の新規基質候補MyRF (Myelin Regulatory Factor)の同定と解析2016
- Author(s)
  中山省悟、弓本佳苗、中山敬一
- Organizer
  BMB2016
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H05575
[Presentation] Large-scale targeted proteomics unveils a global landscape of cancer metabolism2016
- Author(s)
  Keiichi Nakayama
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthrough in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, USA
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15086
[Presentation] SV40 small T antigenはoncogene-induced senescenceを効率的に回避するために必要である2016
- Author(s)
  押川　清孝、松本　雅記、中山　敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パフィシコ横浜・横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K14612
[Presentation] 静止期維持因子p57は+4ポジション幹細胞の制御を介して腸管上皮の恒常性を維持する2016
- Author(s)
  比嘉綱己, 沖田康孝, 松本有樹修, 武石昭一郎, 中津海洋一, 中山敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 発生期におけるクロマチンリモデリング異常は自閉症の原因となる2016
- Author(s)
  片山　雄太, 西山　正章, 昌子　浩孝, 大川　恭行, 川村　敦生, 佐藤　哲也, 須山　幹太, 内匠　透, 宮川　剛, 中山　敬一
- Organizer
  新学術領域研究（マイクロエンドフェノタイプによる精神病態学の創出）若手育成合宿
- Place of Presentation
  埼玉
- Year and Date
  2016-03-03
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] Cell cycle regulation in cancer stem cell2016
- Author(s)
  Nakayama, K. I.
- Organizer
  The Cell Cycle from Mechanism to Therapy
- Place of Presentation
  トロント
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] CHD8 haploinsufficiency in oligodendrocytes results in autistic-like phenotypes in mice2016
- Author(s)
  川村　敦生, 西山　正章, 片山　雄太, 昌子　浩孝, 宮川　剛, 大川　恭行,佐藤　哲也, 須山　幹太, 中山　敬一
- Organizer
  新学術領域研究（グリアアセンブリによる脳機能発現の制御と病態）夏のワークショップ
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] クロマチンリモデリング因子CHD8はオリゴデンドロサイトの分化に必須である2016
- Author(s)
  川村　敦生, 西山　正章, 片山　雄太, 中山　敬一
- Organizer
  新学術領域研究（マイクロエンドフェノタイプによる精神病態学の創出）若手育成合宿
- Place of Presentation
  埼玉
- Year and Date
  2016-03-03
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] Large-scale targeted proteomics unveils a global landscape of cancer metabolism2016
- Author(s)
  Keiichi Nakayama
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthrough in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, USA
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Keap1の「弱い」ユビキチン化活性は迅速なストレス応答に重要である2016
- Author(s)
  弓本佳苗、中山敬一
- Organizer
  BMB2016
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H05575
[Presentation] 造血幹細胞の機能維持におけるユビキチンリガーゼFBXL5による鉄代謝制御の重要性2016
- Author(s)
  武藤義治, 西山正章, 仁田暁大, 諸石寿朗, 中山敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 造血幹細胞の機能維持におけるユビキチンリガーゼFBXL5による鉄代謝制御の重要性2016
- Author(s)
  武藤　義治, 西山　正章, 仁田　暁大, 諸石　寿朗,　中山　敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] CHD8 haploinsufficiency results in autistic-like phenotypes in mice2016
- Author(s)
  Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T., Nakayama, K. I.
- Organizer
  The 26th Hot Spring Harbor International Symposium: Trans-omics: New Approaches in Biology and Medicine 2016
- Place of Presentation
  福岡
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01291
[Presentation] 情報基盤多重モニタリング法（iMPAQT）を用いた細胞老化代謝ネットワークの解析2016
- Author(s)
  押川　清孝、松本　雅記、中山　敬一
- Organizer
  日本プロテオーム学会2016年大会
- Place of Presentation
  北里大学・東京
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16K14612
[Presentation] クロマチンリモデリングによる幹細胞老化と癌の制御機構解明2016
- Author(s)
  仁田　暁大, 西山　正章, 中山　敬一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 次世代プロテオミクスが解き明かす生命システムの全体像2015
- Author(s)
  中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] FBXL12によるALDH3の分解はトロホブラストの分化に必須である2015
- Author(s)
  西山　正章, 仁田　暁大, 弓本　佳苗, 中山　敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] クロマチンリモデリング因子CHD8はオリゴデンドロサイトの分化に必須である2015
- Author(s)
  川村敦生, 西山正章, 片山雄太, 中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01291
[Presentation] 大規模定量プロテオミクスで挑むがん代謝の実体解明2015
- Author(s)
  松本　雅記、中山　敬一
- Organizer
  第38回日本分子生物学会年会/第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290078
[Presentation] 非がん細胞のFbxw7はがんニッチ形成を抑制する2015
- Author(s)
  弓本佳苗、秋吉清百合、上尾裕紀、小野山一郎、上尾裕昭、大野真司、森正樹、三森功士、中山敬一
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H05575
[Presentation] クロマチンリモデリング因子CHD8はオリゴデンドロサイトの分化に必須である2015
- Author(s)
  川村　敦生, 西山　正章, 片山　雄太, 中山　敬一
- Organizer
  新学術領域研究（マイクロエンドフェノタイプによる精神病態学の創出）第1回領域会議
- Place of Presentation
  山梨
- Year and Date
  2015-08-30
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] mTORC1の活性化はFOXK1経路を介して炎症を誘導する2015
- Author(s)
  中津海洋一, 松本雅記, 中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K15086
[Presentation] ユビキチンリガーゼFBXL12によるALDH3分解促進と胸腺細胞分化制御に果たす役割の解析2015
- Author(s)
  仁田　暁大, 西山　正章, 中山　敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 次世代プロテオミクスを用いたがん特性の解明2015
- Author(s)
  中山敬一
- Organizer
  第45回ヒューマンサイエンス総合研究セミナー「がんの多様性に応じた研究・治療ー創薬のパラダイムシフトー
- Place of Presentation
  東京
- Year and Date
  2015-01-13
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] p57は静止状態の腸管幹細胞を制御することで腸管上皮の恒常性を維持する2015
- Author(s)
  比嘉綱己, 沖田康孝, 松本有樹修, 武石昭一郎, 中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 小胞体の膜構造制御と遺伝性痙性対麻痺の病態2015
- Author(s)
  白根道子、橋本寛、中山敬一
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04276
[Presentation] クロマチンリモデリング因子CHD8はオリゴデンドロサイトの分化に必須である2015
- Author(s)
  川村　敦生, 西山　正章, 片山　雄太, 中山　敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 肝臓におけるユビキチンリガーゼFBXL5欠損は鉄代謝異常と肝がんを生じる2015
- Author(s)
  武藤　義治, 西山　正章, 諸石　寿朗, 中山　敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06835
[Presentation] 次世代プロテオミクスを用いたがん特性の解明2015
- Author(s)
  中山敬一
- Organizer
  第45回ヒューマンサイエンス総合研究セミナー「がんの多様性に応じた研究・治療ー創薬のパラダイムシフトー
- Place of Presentation
  東京
- Year and Date
  2015-01-13
- Invited
- Data Source
  KAKENHI-PROJECT-26640080
[Presentation] Fbxw7 inhibits cancer metastasis in a non-cell-autonomous manner2015
- Author(s)
  Kanae Yumimoto, Sayuri Akiyoshi, Hiroki Ueo, Yasuaki Sagara, Ichiro Onoyama, Hiroaki Ueo, Masaki Mori, Koshi Mimori, Keiichi I. Nakayama
- Organizer
  The 10th International Symposium of the Institute Network "Towards the next generation research for cancer and Immunology"
- Place of Presentation
  "Frate" Hall, the alumni hall at the Hokkaido University.
- Year and Date
  2015-07-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05575
[Presentation] 全タンパク質絶対定量がもらたらす生命科学革命2015
- Author(s)
  中山敬一
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮
- Year and Date
  2015-09-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01291
[Presentation] Proteolytic control of iron metabolism by the ubiquitin ligase FBXL5 and its suppressive role in carcinogenesis in the liver2014
- Author(s)
  Muto, Y., Nishiyama, M., Moroishi, T., Yamauchi, T., Nakayama, K. I.
- Organizer
  Annual Meeting of Grants-in-Aid for Scientific Research, “Ubiquitin neobiology”, Symposium for young ubiquitin researcher, International Institute for Advanced Studies
- Place of Presentation
  京都
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] CHD8Lアイソフォームの発生と分化における機能の解析2014
- Author(s)
  片山　雄太, 西山　正章, 大川　恭行, 佐藤　哲也, 須山　幹太, 中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 造血幹細胞におけるユビキチンリガーゼFBXL5による鉄代謝制御の重要性2014
- Author(s)
  武藤　義治, 西山　正章, 諸石　寿朗, 中山　敬一
- Organizer
  新学術領域研究（ユビキチンネオバイオロジー）平成26年度第1回領域会議
- Place of Presentation
  愛知
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 全タンパク質の絶対定量によるがん代謝シフトの解明2014
- Author(s)
  中山敬一
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-26640080
[Presentation] FBXL5-IRP2軸による鉄代謝調節は神経幹細胞の恒常性維持に必須である2014
- Author(s)
  山内　隆好, 西山　正章, 諸石　寿朗, 武藤　義治, 中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 癌幹細胞の理解と制御：癌を完治させる治療戦略2014
- Author(s)
  中山敬一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 次世代プロテオミクスと数理科学の融合が解き明かすがんの秘密2014
- Author(s)
  中山敬一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-26640080
[Presentation] Protrudin regulates ER morphology and function associated with the pathogenesis of hereditary spastic paraplegia2014
- Author(s)
  Michiko Shirane, Yutaka Hashimoto, Fumiko Matsuzaki, Shotaro Saita, Takafumi Ohnishi, Keiichi I. Nakayama
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-25670517
[Presentation] FBXL5-IRP2軸による鉄代謝調節は神経幹細胞の恒常性維持に必須である2014
- Author(s)
  山内　隆好, 西山　正章, 諸石　寿朗, 武藤　義治, 中山　敬一
- Organizer
  新学術領域研究（ユビキチンネオバイオロジー）平成26年度第1回領域会議
- Place of Presentation
  愛知
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 次世代プロテオミクスと数理科学の融合が解き明かすがんの秘密2014
- Author(s)
  中山敬一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Comprehensive profiling of cancer metabolism by the next generation proteomics2014
- Author(s)
  Nakayama KI.
- Organizer
  Kyushu University/Academia Sinica Biliateral Mini-Symposium on Cancer and Stem Cell
- Place of Presentation
  Taipei, Taiwan
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Role of the ubiquitin ligase FBXL5 controlling iron metabolism in hematopoietic stem cells2014
- Author(s)
  Muto, Y., Nishiyama, M., Moroishi, T., Nakayama, K. I.
- Organizer
  The 24th Hot Spring Harbor International Symposium
- Place of Presentation
  福岡
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Deep and absolute quantification of human proteome unveils a global landscape of cancer metabolism2014
- Author(s)
  Nakayama, K. I.
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-11-19
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Deep and absolute quantification of human proteome unveils a global landscape of cancer metabolism2014
- Author(s)
  Nakayama, K. I.
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-26640080
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction on leukemia stem cells through altered microenvironmental regulation2014
- Author(s)
  Takeishi, S., Matsumoto, A., Nakayama, K. I.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-05-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] A neuron-specific isoform of protrudin contributes to establishment of neural polarity2014
- Author(s)
  Takafumi Ohnishi, Yutaka Hashimoto, Shotaro Saita, Keiichi I. Nakayama, Michiko Shirane
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-25670517
[Presentation] FBXL12によるALDH3の分解は幹細胞状態からの脱出プログラムに必須である2014
- Author(s)
  西山　正章, 仁田　暁大, 弓本　佳苗, 中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Regulation of iron metabolism by the FBXL5-IRP2 axis is essential for neural stem cell homeostasis2014
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Muto, Y., Nakayama, K. I.
- Organizer
  Annual Meeting of Grants-in-Aid for Scientific Research, “Ubiquitin neobiology”, Symposium for young ubiquitin researcher, International Institute for Advanced Studies
- Place of Presentation
  京都
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] FBXL12-mediated degradation of ALDH3 is essential for the exit program from the stem cell state2014
- Author(s)
  Nishiyama, M., Nita, A., Yumimoto, K., Nakayama, K. I.
- Organizer
  The 24th Hot Spring Harbor International Symposium
- Place of Presentation
  福岡
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Comprehensive profiling of cancer metabolism by the next generation proteomics2014
- Author(s)
  Nakayama KI.
- Organizer
  International Symposium between Kyushu University Post-Global Centers of Excellence Program and School of Biomedical Sciences, Monash University
- Place of Presentation
  Melbourne, Australia
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction on leukemia stem cells through altered microenvironmental regulation2014
- Author(s)
  Takeishi, S., Matsumoto, A., Nakayama, K. I.
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Deep and absolute quantification of human proteome unveils a global landscape of cancer metabolism2014
- Author(s)
  Nakayama, K. I.
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-11-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] 造血幹細胞の機能維持におけるユビキチンリガーゼFBXL5による鉄代謝制御の重要性2014
- Author(s)
  武藤　義治, 西山　正章, 諸石　寿朗, 中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] ユビキチンリガーゼFBXL5による鉄代謝制御とその破綻2014
- Author(s)
  中山敬一
- Organizer
  第38回鉄バイオサイエンス学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] CHD8はPparγとC/ebpαの転写活性化を介して脂肪分化を誘導する2014
- Author(s)
  喜多　泰之, 西山　正章, 片山　雄太, 中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 癌幹細胞の理解と制御：癌を完治させる治療戦略2014
- Author(s)
  中山敬一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] 次世代プロテオミクスと数理科学の融合が解き明かすがんの秘密2014
- Author(s)
  中山敬一
- Organizer
  生命科学系3分野がん・ゲノム・脳支援活動合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640080
[Presentation] Fbw7 is essential for maintenance of quiescence and function of cancer stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  35th Naito Conference
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2013-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Fbw7 is essential for maintenance of quiescence and function of cancer stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  The 23rd Hot Spring Harbor Symposium: Recent Advances in Stem Cell Biology 2013
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2013-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Next-generation proteomics uncovers the secret of cancer2013
- Author(s)
  Nakayama KI.
- Organizer
  Organelle Homeostasis Research Center: Kick-off Symposium
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] がん治療におけるFbxw7抑制の二面性：光と影2013
- Author(s)
  中山敬一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24 to Regulate Pre-rRNA Processing2013
- Author(s)
  Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Kanae Yumimoto and Keiichi I. Nakayama
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Regulation of trophoblast stem cell fate by SCFFBXL12 ubiquitin ligase complex2013
- Author(s)
  Masaaki Nishiyama and Keiichi I. Nakayama
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Next-generation proteomics uncovers the secret of cancer2013
- Author(s)
  Nakayama, K. I
- Organizer
  Organelle Homeostasis Research Center
- Place of Presentation
  Kick-off Symposium. Fukuoka
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Fbw7 is essential for maintenance of quiescence and function of cancer stem cells2013
- Author(s)
  Nakayama KI.
- Organizer
  The 23rd Hot Spring Harbor Symposium: Recent Advances in Stem Cell Biology 2013
- Place of Presentation
  Fukuoka, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] What is the Warburg effect? Next-generation proteomics uncovers the secret of cancer2013
- Author(s)
  Nakayama KI.
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Cell cycle and cancer stem cells: Abrogation of quiescence by Fbw7 ablation eliminates leukemia stem cells2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  ISEH 42nd Annual Scientific Meeting
- Place of Presentation
  Vienna, Austria
- Year and Date
  2013-08-23
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] What is the Warburg effect? Next-generation proteomics uncovers the secret of cancer2013
- Author(s)
  Keiichi I. Nakayama
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Year and Date
  2013-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-25221303
[Presentation] Absolute quantification oh human proteome by large-scale targeted proteomics2013
- Author(s)
  Nakayama KI.
- Organizer
  HUPO 2013 12th Annual World Congress
- Place of Presentation
  Yokohama, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] 正常幹細胞と癌幹細胞におけるG0期維持機構："G0期追出し療法"による癌根治の可能性2012
- Author(s)
  中山　敬一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] ユビキチン化による鉄代謝制御機構とその破綻2012
- Author(s)
  中山　敬一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Comprehensive and unbiased identification of substrates for ubiquitin ligases by differential proteomics analysis2012
- Author(s)
  Nakayama, K. I
- Organizer
  HUPO 2012 11th World Congress
- Place of Presentation
  Boston, MA
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] 正常幹細胞と癌幹細胞におけるG0期維持機構："G0期追出し療法"による癌根治の可能性2012
- Author(s)
  中山　敬一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Cell cycle, metabolism, and signal transduction in cancer revealed by next-generation proteomics2012
- Author(s)
  Nakayama, K. I
- Organizer
  cer revealed by next-generation proteomics. 2012 American Association for Cancer Research Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Road to Human Proteome Project: Absolute quantification of all human proteins by large-scale targeted proteomics2011
- Author(s)
  Nakayama, K. I
- Organizer
  France-Japan Cancer Meeting
- Place of Presentation
  France-Japan Cancer Meeting
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Road to absolute quantification of all human proteins by large-scale targeted proteomics2011
- Author(s)
  中山敬一、松本雅記
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Road to absolute quantification of all human proteins by large-scale targeted proteomics2011
- Author(s)
  中山敬一、松本雅記
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Comprehensive and unbiased identification of substrates for ubiquitin ligases by differential proteomic analysis2011
- Author(s)
  Nakayama, K. I., Yumimoto, K., Matsumoto, M., Oyamada, K., Moroishi, T
- Organizer
  Cold Spring Harbor Symposium "The Ubiquitin Family"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2011-05-08
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Road to absolute quantification of all human proteins by large-scale targeted proteomics2011
- Author(s)
  Nakayama, K. I
- Organizer
  The 5th International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Onna, Okinawa, Japan
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Comprehensive elucidation of enzyme-substrate relationship by proteomics: Say good-bye to western blotting2010
- Author(s)
  Nakayama, K. I., Yumimoto, K., Matsumoto, M
- Organizer
  6th Global-COE International Symposium: NewHorizons for Modern Science - Biology and Medicine at the Crossroads
- Place of Presentation
  Fukuoka.
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Comprehensive elucidation of enzyme-substrate relationship by proteomics : Say good-bye to western blotting.2010
- Author(s)
  Nakayama, K.I., Yumimoto, K., Matsumoto, M.
- Organizer
  6th Global-COE International Symposium : New Horizons for Modern Science-Biology and Medicine at the Crossroads
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-22240038
[Presentation] Comprehensive elucidation of enzyme-substrate relationship in ubiquitylation by differential proteomics : Say good-bye to western blotting2010
- Author(s)
  Nakayama, K.I.
- Organizer
  Biology of the ubiquitin and the ubiquitin-like systems
- Place of Presentation
  エルサレム
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Comprehensive elucidation of enzyme-substrate relationship in ubiquitylation by differential proteomics: Say good-bye to western blotting.2010
- Author(s)
  Nakayama, K.I.
- Organizer
  Biology of the ubiquitin and the ubiquitin-like systems.
- Place of Presentation
  Jerusalem
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Comprehensive elucidation of enzyme-substrate relationship in ubiquitylation by differential proteomics : Say good-bye to western blotting2010
- Author(s)
  Nakayama, K.I.
- Organizer
  Biology of the ubiquitin and the ubiquitin-like systems
- Place of Presentation
  エルサレム
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Comprehensive elucidation of enzyme-substrate relationship in ubiquitylation by differential proteomics2010
- Author(s)
  Nakayama, K.I.
- Organizer
  Say good-bye to western blotting. Biology of the ubiquitin and the ubiquitin-like systems
- Place of Presentation
  Jerusalem
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Comprehensive elucidation of enzyme-substrate relationship by proteomics : Say good-bye to western blotting.2010
- Author(s)
  Nakayama, K.I., Yumimoto, K., Matsumoto, M.
- Organizer
  6th Global-COE International Symposium : New Horizons for Modern Science-Biology and Medicine at the Crossroads
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PLANNED-22130003
[Presentation] Protrudin依存的小胞輸送によるシナプス制御と神経障害2009
- Author(s)
  白根道子、中山敬一
- Organizer
  MBSJ09
- Place of Presentation
  横浜
- Year and Date
  2009-08-17
- Data Source
  KAKENHI-PROJECT-20054014
[Presentation] Protrudin依存的小胞輸送によるシナプス制御と神経障害2009
- Author(s)
  白根道子、中山敬一
- Organizer
  MBSJO9
- Place of Presentation
  横浜
- Year and Date
  2009-08-17
- Data Source
  KAKENHI-PROJECT-20022030
[Presentation] Comprehensive elucidation of enzyme-substrate relationship by differential proteomics.2009
- Author(s)
  Nakayama, K.I., Yumimoto, K., Matsumoto, M.
- Organizer
  The 4th International Workshop on Cell Regulations in Division and Arrest.
- Place of Presentation
  Onna, Okinawa, Japan
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Comprehensive elucidation of enzyme-substrate relationship by differential proteomics2009
- Author(s)
  Nakayama, K.I., Yumimoto, K., Matsumoto, M.
- Organizer
  The 4th International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Onna, Okinawa, Japan.
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] 定量リン酸化プロテオミクスによるシグナル伝達の包括的解析2009
- Author(s)
  松本雅記、小山田浩二、中山敬一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PUBLICLY-21025025
[Presentation] Conditional inactivation of Fbxw7 results in a defect in cell cycle exit and tumorigenesis. Cold Spring Harbor Symposium "The Cell Cycle"2008
- Author(s)
  Nakayama, K.I., Onoyama, I., Tsunematsu, R., Matsumoto, A., Nakayama, K.
- Organizer
  Cold Spring Harbor
- Place of Presentation
  NY
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] プロトルーディンはRab11-GDPに結合し、特定の方向へ向かう膜輸送により神経突起形成を起こす.2008
- Author(s)
  中山敬一, 白根道子
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] prtoteins Skp2 and Fbw7 control cell cycle exit and re-entry2008
- Author(s)
  Nakayama, K.I.
- Organizer
  ZOMES V: The Fifth International Symposium on the COP9 signalosome, Proteasome, and eIF3: At the interface between signaling & proteolysis
- Place of Presentation
  Yokohama
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Conditional inactivation of Fbxw7 results in a defect in cell cycle exit and tumorigenesis.2008
- Author(s)
  Nakayama, K.I., Onoyama, I., Tsunematsu, R., Matsumoto, A., Nakayama, K.
- Organizer
  Cold Spring Harbor Symposium "The Cell Cycle"
- Place of Presentation
  Cold Spring Harbor, NY
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Conditional inactivation of Fbxw7 results in a defect in cell cycle exit and tumorigenesis2008
- Author(s)
  Nakayama, K. I. et.al.
- Organizer
  Cold Spring Harbor Symposium "The Cell Cycle"
- Place of Presentation
  米国ニューヨーク州コールドスプリングハーバー
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Cell cycle control during T-cell development2008
- Author(s)
  Nakayama, K.I.
- Organizer
  Japan-German Immunology Seminar "International Conference on Immune Regulation in Health and Disease"
- Place of Presentation
  Fukuoka
- Year and Date
  2008-11-05
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] プロトルーディンはRab11-GDPに結合し、特定の方向へ向かう膜輸送により神経突起形成を起こす2008
- Author(s)
  中山敬一, 白根道子
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Conditional inactivation of Fbxw7 results in a defect in cell cycle exit and tumorigenesis2008
- Author(s)
  Nakayama, K. I., et al.
- Organizer
  Cold Spring Harbor Symposium “The Cell Cycle"
- Place of Presentation
  米国ニューヨーク州コールドスプリングハーバー
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Cell cycle control during T-cell development.2008
- Author(s)
  Nakayama, K.I.
- Organizer
  Japan-German Immunology Seminar "International Conference on Immune Regulation in Health and Disease"
- Place of Presentation
  Fukuoka
- Year and Date
  2008-11-05
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Two F-box prtoteins Skp2 and Fbw7 control cell cycle exit and re-entry.2008
- Author(s)
  Nakayama, K. I
- Organizer
  ZOMES V: The Fifth International Symposium on the COP9 signalosome, Proteasome, and eIF3: At the interface between signaling & proteolysis.
- Place of Presentation
  Yokohama
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] 細胞周期を制御するユビキチンリガーゼと発がん2007
- Author(s)
  中山敬一
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] 細胞周期を制御するュビキチンリガーゼと発がん2007
- Author(s)
  中山敬一
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Fbw7 is required for G0 maintenance and tumor suppression: Lessons from a series of conditional knockout mice2007
- Author(s)
  Nakayama, K.I.
- Organizer
  The Second International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Onna, Okinawa, Japan.
- Year and Date
  2007-03-26
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] 定量的リン酸化プロテオミクスによる細胞内シグナル伝達ネットワーク解析2007
- Author(s)
  松本雅記、小山田浩二、中山敬一
- Organizer
  日本ヒトプロテオーム機構第5回大会
- Place of Presentation
  東京
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-18016024
[Presentation] M期特異的リン酸化の大規模定量解析2007
- Author(s)
  松本雅記、小山田浩二、中山敬一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18023017
[Presentation] M期特異的リン酸化の大規模定量解析2007
- Author(s)
  松本雅記、小山田浩二、中山敬一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18016024
[Presentation] ユビキチン化によりエンドサイトーシス・リソソーム輸送される細胞膜蛋白質の同定・解析2007
- Author(s)
  藤田英明、松本雅記、中山敬一, 田中嘉孝
- Organizer
  日本ヒトプロテオーム機構第5回大会
- Place of Presentation
  東京
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-18016024
[Presentation] Fbw7 is required for G0 maintenance and tumor suppression: Lessons from a series of conditional knockout mice.2007
- Author(s)
  Nakayama, K.I.
- Organizer
  The Second International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Onna, Okinawa, Japan
- Year and Date
  2007-03-26
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] 定量的リン酸化プロテオミクスによる細胞内シグナル伝達ネットワーク解析2007
- Author(s)
  松本雅記、小山田浩二、中山敬一
- Organizer
  日本ヒトプロテオーム機構第5回大会
- Place of Presentation
  東京
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-18023017
[Presentation] Fbw7 is a key regulator of cell-cycle arrest and tumorigenesis during development2006
- Author(s)
  Nakayama, K.I., Onoyama, I.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan.
- Year and Date
  2006-06-23
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Fbw7 is a key regulator of cell-cycle arrest and tumorigenesis during development.2006
- Author(s)
  Nakayama, K.I., Onoyama, I.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-23
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Fbw7 is a key regulator of cell cycle exit during development2006
- Author(s)
  Nakayama, K.I.
- Organizer
  US-Japan Cooperative Research Workshop on Mouse Models for Cell Cycle and Ubiquitin-mediated Degradation
- Place of Presentation
  Frederick, MD, USA.
- Year and Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Fbw7 is a key regulator of cell cycle exit during development.2006
- Author(s)
  Nakayama, K.I.
- Organizer
  US-Japan Cooperative Research Workshop on Mouse Models for Cell Cycle and Ubiquitin-mediated Degradation
- Place of Presentation
  Frederick, MD, USA
- Year and Date
  2006-09-07
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] Protrudin-Rab11 system regulates directional membrane traffic to induce neurite formation2005
- Author(s)
  Nakayama, K.I., Shirane, M.
- Organizer
  International Symposium on "Membrane Dynamics and Cell Regulation"
- Place of Presentation
  Fukuoka
- Year and Date
  2005-06-29
- Data Source
  KAKENHI-PROJECT-17013067
[Presentation] Protrudin-Rab11 system regulates directional membrane traffic to induce neurite formation.2005
- Author(s)
  Nakayama, K.I., Shirane, M.
- Organizer
  International Symposium on "Membrane Dynamics and Cell Regulation"
- Place of Presentation
  Fukuoka
- Year and Date
  2005-06-29
- Data Source
  KAKENHI-PROJECT-17107004
[Presentation] クロマチンリモデリングタンパク質CHD7の新規スプライシングバリアントの発見とその機能解析
- Author(s)
  喜多　泰之, 西山　正章, 中山　敬一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Cell cycle and cancer stem cells: Abrogation of quiescence by Fbw7 ablation eliminates leukemia stem cells.
- Author(s)
  Keiichi Nakayama
- Organizer
  ISEH 42nd Annual Scientific Meeting
- Place of Presentation
  Vienna
- Invited
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] 羅的ターゲットプロテオミクスによるヒトプロテオーム定量マップ作成
- Author(s)
  松本　雅記, 中山　敬一
- Organizer
  日本プロテオーム学会大会2014年会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-07-17 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25290078
[Presentation] 次世代ターゲットプロテオミクスによるヒト全代謝経路の絶対定量マッピング
- Author(s)
  松本雅記, 押川清孝, 松崎芙美子, 五島直樹, 夏目徹, 中山敬一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25290078
[Presentation] ユビキチン化による鉄代謝制御機構とその破綻
- Author(s)
  中山　敬一, 西山　正章, 諸石　寿朗
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] FBXL12 targets ALDH3A1 for degradation to regulate the fate of trophoblast stem cells
- Author(s)
  Masaaki Nishiyama and Keiichi I. Nakayama
- Organizer
  The Joint Symposium of the 23rd Hot Spring Harbor International Symposium and the 3rd ‘Grants for Excellent Graduate Schools’ International Symposium
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] ユビキチンリガーゼFBXL5による鉄代謝制御と肝がん
- Author(s)
  諸石　寿朗, 西山　正章, 岩井　一宏, 中山　敬一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] 生体における鉄代謝制御の中心をなすFBXL5-IRP2系の発見
- Author(s)
  諸石　寿朗, 西山　正章, 山内　隆好, 武田　有紀子, 岩井　一宏, 中山　敬一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] MDM2によるRNAヘリカーゼDDX24の非分解的制御機構の解明
- Author(s)
  山内　隆好, 西山　正章, 諸石　寿朗, 弓本　佳苗, 押川　清孝, 中山　敬一
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24 to Regulate Pre-rRNA Processing
- Author(s)
  Yamauchi, T., Nishiyama, M., Moroishi, T., Yumimoto, K., Nakayama, K. I.
- Organizer
  Post-GCOE Symposium & Retreat in Singapore with NUS & TLL
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] Absolute quantification oh human proteome by large-scale targeted proteomics
- Author(s)
  Keiichi Nakayama
- Organizer
  HUPO 2013 12th Annual World Congress
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism in Vivo
- Author(s)
  Moroishi, T., Nishiyama, M., Takeda, Y., Iwai, K., Nakayama, K. I.
- Organizer
  The Joint Symposium of the 7th International Symposium of the Institute Network and the 45th IDAC Symposium, the 2nd Symposium for Joint Usage/Research Center of Aging
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24501305
[Presentation] リン酸化定量プロテオミクスによるシグナル伝達研究
- Author(s)
  松本　雅記、中津海　洋一、中山　敬一
- Organizer
  第１４回蛋白質科学会年会
- Place of Presentation
  ワークピア横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-25290078

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# of Collaborated Products: 79 results
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Nakayama Keiichi 中山 敬一

NAKAYAMA Keiichi 中山 敬一

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幹細胞における時空間リプログラミングの機構解明と疾患との関わりの研究Principal Investigator

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Investigation for mechanisms underlying cell cycle regulation and metabolism in stem cellsPrincipal Investigator

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幹細胞における細胞周期制御と代謝系との連関に関する基盤的研究Principal Investigator

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代謝リモデリングによる適者生存メカニズムの研究Principal Investigator

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がん細胞の代謝アダプテーションPrincipal Investigator

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新規モデルマウスを用いた自閉症マイクロエンドフェノタイプの解明Principal Investigator

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Deciphering the signal transduction pathway linking nutrition and inflammationPrincipal Investigator

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Elucidation of Warburg effect in cancer with the next-generation proteomicsPrincipal Investigator

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Integrative study for functional analyses of stem cell maintenance factors and visualization of stem cellsPrincipal Investigator

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Nakayama Keiichi 中山敬一

NAKAYAMA Keiichi 中山敬一