Ito Hiroyasu 伊藤弘康

… Alternative Names

ITO Hiroyasu 伊藤弘康

伊藤弘康イトウヒロヤス

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Researcher Number	80373075
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 藤田医科大学, 医学部, 教授 2023: 岐阜大学, 大学院医学系研究科, 准教授 2016 – 2020: 岐阜大学, 大学院医学系研究科, 准教授 2015: 岐阜大学, 医学系研究科, 准教授 2012 – 2015: 岐阜大学, 医学(系)研究科(研究院), 准教授 … More 2013: 岐阜大学, 大学院医学系研究科, 准教授 2012: 岐阜大学, 大学院・医学系研究科, 講師 2011: 岐阜大学, 医学研究科, 講師 2009: 岐阜大学, 大学院・医学系研究科, 講師 2008: 岐阜大学, 医学研究科, 講師 2006: Gifu University, Graduate School of Medicine, Lecturer 2005: 愛知医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Laboratory medicine / Basic Section 54030:Infectious disease medicine-related / Gastroenterology Except Principal Investigator Gastroenterology / Laboratory medicine / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 59040:Nutrition science and health science-related / Basic Section 53010:Gastroenterology-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Eating habits / Tumor biology
Keywords	Principal Investigator HBV / ワクチン療法 / 動物モデル / インドールアミン酸素添加酵素 / ＮＫＴ細胞 / ワクチン / トリプトファン代謝 / スペルミジン / cGAMP / K3SPG … More / マウスモデル / 免疫学 / HSV-Tkマウス / 肝障害 / HSV-TKマウス / B型肝炎 / HSV-TK / 抗HBV剤 / 宿主免疫応答 / 小動物疾患モデル / 癌進展 / 癌免疫療法 / 癌転移 / 免疫抑制因子 / 一酸化窒素 / 腫瘍免疫 / NKT細胞 / α-ガラクトシルセラミド / 癌免疫 / 一酸化窒素合成酵素 … More Except Principal Investigator ソイスタチン / ラクトスタチン / Caco-2細胞 / アルカリフォスファターゼ / IIAEK / FP / コレステロール / ペプチド / 肝細胞移植 / 免疫拒絶 / CD40 / IL-2 / α-galactosylceramide / B型肝炎ウイルス / サイトカイン / 液性免疫 / SARS-CoV-2 / ポリアミン / 免疫疲弊 / エピゲノム / 細胞治療 / 肝再生 / 肝再生不全 / 細胞老化 / 脂肪由来幹細胞 / 持続性肝不全 / アルカリホスファターゼ / AlphaFold2 / PPARα / HepG2細胞 / マウス / アルカリ性ホスファターゼ / ミセル / β-コングリシニン / 脂質ラフト / 胆汁酸 / 動脈硬化 / ペプチドアレイ / Caco-2 / 大豆β-コングリシニン / ラット / GVHD / イメージング / 再生医療 / 量子ドット / 戻し交配 / GFP / 肝細胞置換率 / 肝不全 / 細胞移植 / 肝細胞キメラマウス / CD4OL / cytotoxic T lymphocyte / NKT cell / transgenic mouse / hepatitis B virus / CD40L / 細胞障害性Tリンパ球 / NKT細胞 / トランスジェニックマウス / 癌免疫 / 微小環境 / 腫瘍 / MDSC / マクロファージ / T細胞 / 腫瘍微小環境 / 腫瘍免疫 / 細胞障害性T細胞 / 肝炎ウイルス / 急性肝炎 / 細胞傷害性T細胞 / インドールアミン酸素添加酵素 / CPTII遺伝子 / FACS / フローサイトメトリー / 遺伝子解析 / リアノジン受容体 / 細胞内カルシウム / 筋障害 / スタチン製剤 / 臨床化学 / 炎症・免疫 / 生理活性物質 / 臨床検査医学 Less

心理的快ストレスを利用した慢性HBV感染症に対する治療的ワクチン療法の開発Principal Investigator
- Principal Investigator
  
  伊藤弘康
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Fujita Health University
エピゲノム変化に伴う免疫細胞の疲弊予防と関連遺伝子の解明
- Principal Investigator
  
  安藤達也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Fujita Health University
多角的なSARS-CoV-2免疫獲得状況の調査研究
- Principal Investigator
  
  藤垣英嗣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Fujita Health University
トリプトファン代謝制御を利用した慢性HBV感染症に対する治療的ワクチン療法の開発Principal Investigator
- Principal Investigator
  
  伊藤弘康
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Fujita Health University
Establishment of a liver regeneration treatment model based on cell transplantation and development of a new treatment against immune rejection.
- Principal Investigator
  
  Ishikawa Tetsuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya University
Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Gifu University
Development of therapeutic vaccine therapy using chronic HBV infection modelPrincipal Investigator
- Principal Investigator
  
  Ito Hiroyasu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Fujita Health University
  Gifu University
Fundamental study on the lipid lowering peptides derived from food proteins
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  Gifu University
Development of an HBV infection mouse model using HSV-TK-WT mousePrincipal Investigator
- Principal Investigator
  
  Ito Hiroyasu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gifu University
Monitoring of transplanted hepatocytes and analysis of immune rejection responses in the hepatocyte chimeric mouse system.
- Principal Investigator
  
  Ishikawa Tetsuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Analysis of inflammation and immune cells in tumor microenvironment.
- Principal Investigator
  
  Shirota Hidekazu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Inhibition of iNOS activity enhances the anti-tumor effects of alpha-galactosylceramide in cancer modelPrincipal Investigator
- Principal Investigator
  
  Ito Hiroyasu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
The role of IDO in the HBV-related liver diseases.
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Gifu University
転移性腫瘍に対するNKT細胞免疫と免疫抑制因子の制御を用いた新規癌免疫療法の開発Principal Investigator
- Principal Investigator
  
  伊藤弘康
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Screening and gene analysis for the protection from muscle damage by statin drugs
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
The pathophysiologic role of indoleamine 2, 3-dioxygenase in viral infectious diseases
- Principal Investigator
  
  SAITOU Kuniaki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Analysis and therapeutic application of crosstalk between innate immunity and acquired immunity in viral hepatitis.
- Principal Investigator
  
  ISHIKAWA Tetsuya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Aichi Medical University

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All Journal Article Presentation Book

[Book] B型肝炎ワクチンとアジュバント「次世代アジュバント開発のためのメカニズム解明と安全性評価」2017
- Author(s)
  伊藤弘康、石川哲也
- Publisher
  ファインケミカル
- ISBN
  9784781312385
- Data Source
  KAKENHI-PROJECT-16K09354
[Journal Article] Optimal timing of SARS-CoV-2 vaccination prior to cardiovascular surgery under cardiopulmonary bypass2024
- Author(s)
  Hayashi Ryosuke、Takami Yoshiyuki、Fujigaki Hidetsugu、Amano Kentaro、Akita Kiyotoshi、Yamana Koji、Maekawa Atsuo、Saito Kuniaki、Takagi Yasushi
- Journal Title
  
  The International Journal of Artificial Organs
  
  Volume: 47 Issue: 3 Pages: 147-154
- DOI
  10.1177/03913988241234475
- Data Source
  KAKENHI-PROJECT-23K27843
[Journal Article] Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts2023
- Author(s)
  Takagi Erina、Terakura Seitaro、Fujigaki Hidetsugu、Okamoto Akinao、Miyao Kotaro、Sawa Masashi、Morishita Takanobu、Goto Tatsunori、Ozawa Yukiyasu、Nishida Tetsuya、Fukushima Nobuaki、Ozeki Kazutaka、Hanajiri Ryo、Saito Kuniaki、Murata Makoto、Tomita Akihiro、Kiyoi Hitoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 4 Pages: 462-471
- DOI
  10.1007/s12185-023-03648-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15323, KAKENHI-PROJECT-21K08381, KAKENHI-PROJECT-22K08501, KAKENHI-PROJECT-21K08387, KAKENHI-PROJECT-21K08407, KAKENHI-PROJECT-23K27624, KAKENHI-PROJECT-23K27843
[Journal Article] Comparison of the Serial Humoral Immune Response according to the Immunosuppressive Treatment after SARS-CoV-2 mRNA Vaccination2023
- Author(s)
  Menjo Hiroya、Hasegawa Midori、Fujigaki Hidetsugu、Ishihara Takuma、Minatoguchi Shun、Koide Shigehisa、Hayashi Hiroki、Saito Midori、Takahashi Kazuo、Ito Hiroyasu、Yuzawa Yukio、Saito Kuniaki、Tsuboi Naotake
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 23 Pages: 3445-3454
- DOI
  10.2169/internalmedicine.1949-23
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-12-01
- Language
  English
- Data Source
  KAKENHI-PROJECT-23K27843
[Journal Article] Treatment with hepatocyte transplantation in a novel mouse model of persistent liver failure2022
- Author(s)
  Tamaki Y, Shibata Y, Hayakawa M, Kato N, Machii A, Ikeda Y, Nanizawa E,Hayashi Y, Suemizu H, Ito H, Ishikawa T
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 32 Pages: 101382-101382
- DOI
  10.1016/j.bbrep.2022.101382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07959
[Journal Article] Novel hepatitis B virus infection mouse model using herpes simplex virus type 1 thymidine kinase transgenic mice2020
- Author(s)
  Kanbe Ayumu、Ishikawa Tetsuya、Hara Akira、Suemizu Hiroshi、Nanizawa Eri、Tamaki Yuki、Ito Hiroyasu
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 36 Issue: 3 Pages: 782-789
- DOI
  10.1111/jgh.15142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08440
[Journal Article] In utero exposure to di(2-ethylhexyl)phthalate suppresses blood glucose and leptin levels in the offspring of wild-type mice.2019
- Author(s)
  Hayashi Y, Ito Y, Naito H, Tamada H, Yamagishi N, Kondo T, Ishikawa T, Gonzalez FJ, Nakajima T.
- Journal Title
  
  Toxicology
  
  Volume: 415 Pages: 49-55
- DOI
  10.1016/j.tox.2019.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09354
[Journal Article] Secreted ectodomain of SIGLEC-9 and MCP-1 synergistically improve acute liver failure in rats by altering macrophage polarity2017
- Author(s)
  Ito T, Ishigami M, Matsushita Y, Hirata M, Matsubara K, Ishikawa T, Hibi H, Ueda M, Hirooka Y, Goto H, Yamamoto A
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 44043-44043
- DOI
  10.1038/srep44043
- NAID
  120006306638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670863, KAKENHI-PROJECT-15K08996, KAKENHI-PROJECT-16K09354, KAKENHI-PROJECT-16H05540
[Journal Article] Intact metabolite profiling of mouse brain by probe electrospray ionization/triple quadrupole tandem mass spectrometry (PESI/MS/MS) and its potential use for local distribution analysis of the brain2017
- Author(s)
  Hayashi Yumi、Zaitsu Kei、Murata Tasuku、Ohara Tomomi、Moreau St?phane、Kusano Maiko、Tanihata Hiroshi、Tsuchihashi Hitoshi、Ishii Akira、Ishikawa Tetsuya
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 983 Pages: 160-165
- DOI
  10.1016/j.aca.2017.06.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09354, KAKENHI-PROJECT-15H02530, KAKENHI-PROJECT-16K19271
[Journal Article] Inhibition of iNOS activity enhances the anti-tumor effects of alpha-galactosylceramide in established murine cancer model.2015
- Author(s)
  Ito H, Ando T, Seishima M.
- Journal Title
  
  Oncotarget.
  
  Volume: 6(39) Issue: 39 Pages: 41863-41874
- DOI
  10.18632/oncotarget.6172
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460679
[Journal Article] Inhibition of induced nitric oxide synthase enhances the anti-tumor effects on cancer immunotherapy using TLR7 agonist in mice.2015
- Author(s)
  Ito H, Ando T, Ogiso H, Arioka Y, Seishima M.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 64(4) Issue: 4 Pages: 429-436
- DOI
  10.1007/s00262-014-1644-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460679
[Journal Article] Combination therapy with α-galactosylceramide and a Toll-like receptor agonist exerts an augmented suppressive effect on lung tumor metastasis in a mouse model.2015
- Author(s)
  Ando T, Ito H, Arioka Y, Ogiso H, Seishima M.
- Journal Title
  
  Oncology Reports
  
  Volume: 33 Issue: 2 Pages: 826-832
- DOI
  10.3892/or.2014.3634
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460679
[Journal Article] Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model.2015
- Author(s)
  Ito H, Ando T, Arioka Y, Saito K, Seishima M.
- Journal Title
  
  Immunology
  
  Volume: 144(4) Issue: 4 Pages: 621-630
- DOI
  10.1111/imm.12413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460679
[Journal Article] Induction of HBsAg-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity2014
- Author(s)
  Ito H, Ando T, Ando K, Ishikawa T, Saito K, Moriwaki H, Seishima M
- Journal Title
  
  Immunology
  
  Volume: 印刷中 Issue: 4 Pages: 614-623
- DOI
  10.1111/imm.12274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361
[Journal Article] Kynurenine production mediated by indoleamine 2, 3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1842(9) Issue: 9 Pages: 1464-71
- DOI
  10.1016/j.bbadis.2014.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361, KAKENHI-PROJECT-26860376
[Journal Article] Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression.2011
- Author(s)
  Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M
- Journal Title
  
  FASEB J
  
  Volume: 25 Issue: 4 Pages: 1133-44
- DOI
  10.1096/fj.10-168351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-22590728
[Journal Article] Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model2011
- Author(s)
  Ito H, Hoshi M, Saito K, 他
- Journal Title
  
  J Immunol
  
  Volume: 185(8) Pages: 4554-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Tsurumi H, Hoshi M, Kanemura N, Goto N, Kasahara S, Shimizu M, Ito H, Saito K, Hirose Y, Yamada T, Takahashi T, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Ann Hematol.
  
  Volume: 90(4) Issue: 4 Pages: 409-16
- DOI
  10.1007/s00277-010-1093-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin2011
- Author(s)
  Osawa Y, Kanamori H, Seki E, Hoshi M, Ohtaki H, Yasuda Y, Ito H, Suetsugu A, Nagaki M, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Issue: 40 Pages: 34800-34808
- DOI
  10.1074/jbc.m111.235473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06850, KAKENHI-PROJECT-20390167, KAKENHI-PROJECT-21390179
[Journal Article] Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Saito K, 他13名
- Journal Title
  
  Ann Hematol
  
  Volume: 90(4) Pages: 409-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Comparison of chemiluminescence enzyme immunoassay (CLEIA) with ELISA for the determination of anti-cyclic citrullinated peptide antibodies2010
- Author(s)
  Tanaka R, Takemura M, Sato M, Yamada Y, Nakagawa T, Horibe T, Hoshi M, Ohtaki H, Ito H, Seishima M, Shimizu K.
- Journal Title
  
  Clin Chim Acta
  
  Volume: 411 Issue: 1-2 Pages: 22-5
- DOI
  10.1016/j.cca.2009.09.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] Ability of IDO to attenuate liver injury in alpha-galactosylceramide induced hepatitis model2010
- Author(s)
  Ito H, et al 10名
- Journal Title
  
  J Immunol
  
  Volume: 185 Pages: 4554-4560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] リポ蛋白X2010
- Author(s)
  清島満、伊藤弘康
- Journal Title
  
  日本臨床
  
  Volume: 68 Pages: 46-49
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] Serum concentration of L-kynureninepredicts the clinical outcome of patientswith diffuse large B-cell lymphoma treated with R-CHOP2010
- Author(s)
  Yoshikawa T, Hara T, Tsurumi H, Goto N, Hoshi M, Kitagawa J, Kanemura N, Kasahara S, Ito H, Takemura M, Saito K, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Eur J Haematol.
  
  Volume: 84(4) Issue: 4 Pages: 304-309
- DOI
  10.1111/j.1600-0609.2009.01393.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Ability of IDO to attenuate liver in juryin alpha-galactosylceramide-in duced hepatitis model2010
- Author(s)
  Ito H, Hoshi M, Ohtaki H, Taguchi A, AndoK, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(8) Issue: 8 Pages: 4554-60
- DOI
  10.4049/jimmunol.0904173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, Hara A, Taguchi A, OhtakiH, Tanaka R, Fujigaki H, Osawa Y, TakemuraM, Matsunami H, Ito H, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(6) Issue: 6 Pages: 3305-12
- DOI
  10.4049/jimmunol.0901150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, 他10名
- Journal Title
  
  J Immunol
  
  Volume: 185(6) Pages: 3305-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Changes in serum tryptophan catabolism as an indicator of disease activity in adult T-cell leukemia/lymphoma2009
- Author(s)
  Hoshi M, Ito H, Fujigaki H., 他8名
- Journal Title
  
  Leuk Lymphoma 50
  
  Pages: 1372-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Changes in serum tryptophan catabolism as an indicator of disease activity in adult T-cell leukemia/lymphoma2009
- Author(s)
  Hoshi M, Ito H, Fujigaki H, Takemura M, Takahashi T, Tomita E, Ohyama M, Tanaka R, Ohtaki H, Saito K, Seishima M.
- Journal Title
  
  LeukLymphoma.
  
  Volume: 50(8) Issue: 8 Pages: 1372-1374
- DOI
  10.1080/10428190903045393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Interaction between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Valpha14 NKT cells2009
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, HoshiM, Tanaka R, Osawa Y, Yokochi T, MoriwakiH, Saito K, Seishima M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 389(2) Issue: 2 Pages: 229-34
- DOI
  10.1016/j.bbrc.2009.08.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following2009
- Author(s)
  Hoshi M, Saito K, Murakami, 他7名
- Journal Title
  
  Neurosci Res. 63
  
  Pages: 194-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Statin-induced Ca2+release wasincreased in B lymphocytes in patients who showed elevated serum creatine kinase during statin treatment.2009
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M,Seishima M.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 16 Pages: 870-7
- URL
  https://www.jstage.jst.go.jp/browse/jat
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse2009
- Author(s)
  Hoshi M, Saito K, Murakami Y, Taguchi A, Fujigaki H, Tanaka R, Takemura M, Ito H, Hara A, Seishima M.
- Journal Title
  
  Neurosci Res.
  
  Volume: 63(3) Issue: 3 Pages: 194-198
- DOI
  10.1016/j.neures.2008.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Interaction, between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Valpha14 NKT cells2009
- Author(s)
  Ohtaki H, Ito H, Ando K., 他8名
- Journal Title
  
  Biochem Biophys Res Commun 389
  
  Pages: 229-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Localization and spatiotemporal expression of IDO following transient forebrain ischemia in gerbils.2008
- Author(s)
  Taguchi A, Hara A, Saito K, 他4名
- Journal Title
  
  Brain Res. 1217
  
  Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Presentation] Cholesterol-lowering pentapeptide IIAEK (lactostatin) specifically interacts with intestinal alkaline phosphatase to improve cholesterol metabolism2022
- Author(s)
  Asahi Takeuchi, Kentaro Hisamatsu, Natsuki Okumura, Keigo Takada, Maihemuti Mijiti, Yuyang Ye, Arata Banno, Emiko Yanase, Yoshihito Ueno, Satoshi Nagaoka
- Organizer
  22th IUNS-International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] 新規HBV感染マウスモデル作製と宿主免疫応答の解析2019
- Author(s)
  神戸歩、伊藤弘康、石川哲也
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09351
[Presentation] 歯髄幹細胞無血清培養上清による難治性肝疾患での有用性の検討-急性・慢性肝炎動物モデルにおける効果発現メカニズムの違いに着目して2017
- Author(s)
  伊藤隆徳、田中卓、山本健太、安藤祐資、安田諭、野村彩、加藤幸一郎、石津洋二、葛谷貞二、本多隆、林和彦、石上雅敏、廣岡芳樹、石川哲也、後藤秀実
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09354
[Presentation] マウスモデルを使用した慢性B型肝炎に対する治療用ワクチン開発の試み2017
- Author(s)
  伊藤弘康、清島満、石川哲也
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09354
[Presentation] IL-4 modulate the tumor microenvironment and response to2015
- Author(s)
  Shukuei Ito
- Organizer
  第19回日本がん免疫学会総会、第23回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  伊藤国際学術研究センター　伊藤謝恩ホール(東京)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] Toll様受容体アゴニストと一酸化窒素合成酵素の抑制を用いた抗腫瘍効果の検討2015
- Author(s)
  伊藤弘康、安藤達也、小木曽英介、清島　満
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460679
[Presentation] IL-4 modulate the tumor microenvironment and response to2015
- Author(s)
  Shukuei Ito, Hidekazu Shirota, Chikashi Ishioka
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] IL-4 derived from T follicular helper cells in tumor draining2015
- Author(s)
  Hidekazu Shirota, Dennis Klinman, Shukuei Ito, Chikashi Ishioka
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430103
[Presentation] インドールアミン酸素添加酵素の発現制御を用いたHBV特異的細胞障害性T細胞誘導効果の検討2013
- Author(s)
  伊藤弘康、安藤達也、石川哲也、清島満
- Organizer
  第60回日本臨床検査医学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659361
[Presentation] マウスB型急性肝炎モデルにおけるインドールアミン酸素添加酵素の解析2013
- Author(s)
  伊藤弘康、大瀧博文、安藤達也、安藤量基、石川哲也、森脇久隆、清島満
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659361
[Presentation] Toll様受容体アゴニストとインドールアミン酸素添加酵素制御を用いた抗腫瘍効果の検討2013
- Author(s)
  伊藤　弘康
- Organizer
  第53回日本臨床化学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-25460679
[Presentation] インドールアミン酸素添加酵素の発現抑制によるHBV特異的細胞障害性T細胞誘導効果2013
- Author(s)
  伊藤弘康、安藤量基、石川哲也、森脇久隆、清島満
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24659361
[Presentation] Is the measurement of Ca2+-release inCD19+ B cells stimulated by statin useful for prediction of muscle damage as a side effect?2012
- Author(s)
  Mori I, Hattori T, Osawa Y, Kanamori H, Kajita K, Morita H, Ishizuka T, Saito K, Ito H, Seishima M
- Organizer
  第44回日本動脈硬化学会総会・学術集会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] 細胞障害性T細胞により誘発されるマウス劇症肝炎モデルにおけるindoleamine 2, 3-dioxygenaseの解析2012
- Author(s)
  安藤達也、大瀧博文、伊藤弘康、星雅人、石川哲也、斎藤邦明、清島満
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659361
[Presentation] Inhibition of acid sphingomyelinase causes hepatic glucose intolerance and insulin resistance2010
- Author(s)
  Osawa Y, Ito H, Suetusgu A, Nagaki M, Moriwaki H, Seishima M
- Organizer
  DDW 2010
- Place of Presentation
  New Orlealls
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] 高脂血症治療剤による培養細胞に対するCa^<2+>放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海北陸支部例会連合大会
- Place of Presentation
  名古屋市
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Ca2+releasing effect of stains on human CD19+primary B cells.2010
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Inhibition of acid sphingomyelinasecauses hepatic glucose intolerance and insulin resistance2010
- Author(s)
  Osawa Y, Ito H, Suetsugu A, Nagaki M, Moriwaki H, Seishima M.
- Organizer
  DDW 2010 New Orleans
- Place of Presentation
  USA
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Ca^<2+> releasing effect of statins on human CD19+ primary B cells2010
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] 高脂血症治療剤による培養細胞に対するCa2+放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海・北陸支部例会連合大会
- Place of Presentation
  名古屋
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179

1. SEISHIMA Mitsuru (10171315)

# of Collaborated Projects: 7 results

# of Collaborated Products: 27 results
2. ISHIKAWA Tetsuya (10288508)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
3. SAITOU Kuniaki (80262765)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YAMAMOTO Yasuko (00331869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Nagaoka Satoshi (50202221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 松井利郎 (20238942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 上野義仁 (20250467)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 本多裕之 (70209328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 林由美 (30632707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. 安藤達也 (50796068)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. FUNATO Tadao (70165455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OSAWA Yousuke (60447787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. MORI Ichiro (40444327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. KANAMORI Hiromitsu (20456502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. Shirota Hidekazu (50451555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. SHIRAKAMI Yohei (50632816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAKUMU Shinichi (10115545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OKUMURA Akihiko (70288512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 清水雅仁 (90402198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 出田貴康 (90610379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 櫻井浩平 (10608756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 藤垣英嗣 (00612631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 近藤征史 (00378077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 長谷川みどり (40298518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 成瀬寛之 (50319266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 坪井直毅 (50566958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 古関竹直 (70850551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 冨田章裕 (80378215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 岡本晃直 (80775049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Kanbe Ayumu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. YUKAWA Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. MATSUNAGA Tamihide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. SUEMIZU Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HIBI Hideharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 斉藤邦明

# of Collaborated Projects: 0 results

# of Collaborated Products: 21 results
36. 山本朗仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 葉名尻良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Hiroyasu 伊藤 弘康

ITO Hiroyasu 伊藤 弘康

伊藤 弘康 イトウ ヒロヤス

Research Projects

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Co-Researchers

心理的快ストレスを利用した慢性HBV感染症に対する治療的ワクチン療法の開発Principal Investigator

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トリプトファン代謝制御を利用した慢性HBV感染症に対する治療的ワクチン療法の開発Principal Investigator

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Development of therapeutic vaccine therapy using chronic HBV infection modelPrincipal Investigator

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Development of an HBV infection mouse model using HSV-TK-WT mousePrincipal Investigator

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Inhibition of iNOS activity enhances the anti-tumor effects of alpha-galactosylceramide in cancer modelPrincipal Investigator

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転移性腫瘍に対するNKT細胞免疫と免疫抑制因子の制御を用いた新規癌免疫療法の開発Principal Investigator

Principal Investigator

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Ito Hiroyasu 伊藤弘康

ITO Hiroyasu 伊藤弘康

伊藤弘康イトウヒロヤス