KAZUKI Yasuhiro 香月康宏

Researcher Number	90403401
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 鳥取大学, 医学部, 教授 2020 – 2021: 鳥取大学, 医学部, 准教授 2014 – 2019: 鳥取大学, 医学(系)研究科(研究院), 准教授 2015: 鳥取大学, 医学研究院, 准教授 2013: 鳥取大学, 医学系研究科, 助教 … More 2012: 鳥取大学, 大学院・医学研究科, 助教 2011: Tottori University, 医学(系)研究科(研究院), 助教 2011: 鳥取大学, 大学院・医学系・研究科, 助教 2007 – 2011: Tottori University, 大学院・医学系研究科, 助教 2009 – 2010: 鳥取大学, 医学研究科, 助教 2006: 鳥取大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Human genetics / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related Except Principal Investigator Medical pharmacy / Human genetics / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 56030:Urology-related … More / Basic Section 42040:Laboratory animal science-related / Basic Section 38060:Applied molecular and cellular biology-related / Integrative animal science / Drug development chemistry Less
Keywords	Principal Investigator リサーチバイオリソース / ヒト化モデル動物 / 再生医療 / 毛細血管拡張性運動失調症 / 染色体工学 / 遺伝子治療 / ヒト人工染色体 / iPS細胞 / 遣伝子治療 / ES細胞 … More Except Principal Investigator … More 染色体工学 / ゲノム編集 / ヒト人工染色体 / 表現型スクリーニング / 人工染色体 / 抗体医薬 / 薬学 / 応用動物 / 薬物代謝 / 間葉系幹細胞 / 筋ジストロフィー / 遺伝子治療 / 分子進化 / 機能抗体 / 染色体工学技術 / KS-ES細胞 / クラインフェルター症候群 / がん研究 / 免疫不全 / 人工染色体ベクター / 安全性予測 / 薬効予測 / 薬物動態 / 抗体 / Fcガンマ受容体 / 進化工学 / モノクローナル抗体 / Ｗｎｔ/βカテニンシグナル / CRISPR-Cas9 / 免疫グロブリン / VHH / R-spondin / ペプチド / 指向性進化 / ペプチド医薬 / Wnt/βカテニンシグナル / 相補性決定領域 / ヒト抗体 / HLA A24 / GalT / 異種移植 / ブタ / 予測 / 評価系 / 評価 / ヒト予測 / CES / プロドラッグ / 試験系 / 性差 / 遺伝子導入 / CYP3A / 抗体医薬産生 / ヒトの薬物動態・代謝予測系 / mesoangioblast細胞 / 遺伝子治療学 / ES細胞 Less

完全ヒト抗体産生ウサギ作製によるゲノム動作原理解明および高機能抗体取得の試みPrincipal Investigator
- Principal Investigator
  
  香月康宏
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Tottori University
ゲノム編集誘導性分子多様化による、機能抗体・ペプチド表現型スクリーニングシステム
- Principal Investigator
  
  冨塚一磨
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of a predictive mouse model for drug efficacy of IgG antibody therapeutics targeting cancer cells
- Principal Investigator
  
  濱道修生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tottori University
染色体工学的アプローチによるクラインフェルター症候群の原因遺伝子同定
- Principal Investigator
  
  西川結梨
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Tottori University
Generation of humanized rats expressing multiple drug-metabolizing enzyme-related genes using mammalian artificial chromosome technologiesPrincipal Investigator
- Principal Investigator
  
  KAZUKI Yasuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tottori University
Development of induciblydiversified antibody-expressing cell library that enables antibody phenotypic screening
- Principal Investigator
  
  TOMIZUKA KAZUMA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Production of genetically modified pigs by combined techniques of chromosome engineering and genome editing
- Principal Investigator
  
  OTOI Takeshige
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokushima
Generation of humanized rats expressing drug-metabolizing enzyme using human artificial chromosome and genome editing technologiesPrincipal Investigator
- Principal Investigator
  
  KAZUKI Yasuhiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tottori University
Development of rapid system for generation of consomic mice via chromosome transfer and elimination technologiesPrincipal Investigator
- Principal Investigator
  
  KAZUKI Yasuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tottori University
Establishment of in vitro and in vivo models for human CES which promote rational development of ester-based prodrugs
- Principal Investigator
  
  Chiba Kan
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba University
Study for sex differences of CYP3A enzymes using trans-chromosomic mice containing a human CYP3A gene cluster
- Principal Investigator
  
  KOBAYASHI Kaoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba University
iPS細胞とヒト人工染色体ベクターを用いた毛細血管拡張性運動失調症の遺伝子治療Principal Investigator
- Principal Investigator
  
  香月康宏
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Human genetics
- Research Institution
  Tottori University
Development of the antibody drug production system using a highly efficient artificial chromosome vector.
- Principal Investigator
  
  NISHIDA Tadashi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Tottori University
Gene therapy of Duchenne muscular dystrophy using own stem cells and human artificial chromosome
- Principal Investigator
  
  OSHIMURA Mitsuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Human genetics
- Research Institution
  Tottori University
Creation of CYP3A- and P-glycoprotein-humanized mouse and its application to the study of drug metabolism and disposition
- Principal Investigator
  
  CHIBA Kan
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba University
スティーブンス・ジョーンソン症候群モデルマウス創製の試み
- Principal Investigator
  
  千葉寛
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba University
Generation of gene therapy method for ataxia-telangiectasia using a human artificial chromosomePrincipal Investigator
- Principal Investigator
  
  KAZUKI Yasuhiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  Tottori University
Construction of human artificial chromosome for gene therapy of Duchenne muscular dystrophy
- Principal Investigator
  
  OSHIMURA Mitsuo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Tottori University

[Book] 進化するゲノム編集技術、真下知士　城石俊彦　監修2015
- Author(s)
  香月康宏、押村光雄
- Total Pages
  341
- Publisher
  （株）NTS
- Data Source
  KAKENHI-PROJECT-15H04285
[Book] 幹細胞とヒト人工染色体ベクターの出会いVol.19, No.12007
- Author(s)
  香月康宏、押村光雄
- Publisher
  アニテックス
- Data Source
  KAKENHI-PROJECT-18390107
[Book] ヒト人工染色体ベクター導入と遺伝子・再生医療への可能性vol.10No.42006
- Author(s)
  香月康宏、押村光雄
- Publisher
  分子呼吸器病
- Data Source
  KAKENHI-PROJECT-18390107
[Journal Article] 哺乳類ゲノムをデザイン・構築・解析するための染色体工学技術2022
- Author(s)
  岸間菜々美、山崎匡太郎、香月康宏
- Journal Title
  
  実験医学（羊土社）
  
  Volume: 41 Pages: 424-428
- Data Source
  KAKENHI-PROJECT-20H03173
[Journal Article] マウス人工染色体を用いたヒト化マウス・ラット作製と創薬研究への応用2020
- Author(s)
  森脇崇史、香月康宏
- Journal Title
  
  月刊細胞
  
  Volume: 52 Pages: 424-427
- Data Source
  KAKENHI-PROJECT-20H03173
[Journal Article] 染色体導入技術とゲノム編集技術によるヒト化動物・疾患モデル細胞の作製2020
- Author(s)
  香月加奈子、香月康宏
- Journal Title
  
  医学のあゆみ
  
  Volume: 293 Pages: 812-819
- Data Source
  KAKENHI-PROJECT-20H03173
[Journal Article] Transchromosomic technology for genomically humanized animals2020
- Author(s)
  Moriwaki Takashi、Abe Satoshi、Oshimura Mitsuo、Kazuki Yasuhiro
- Journal Title
  
  Experimental Cell Research
  
  Volume: 390 Issue: 2 Pages: 111914-111914
- DOI
  10.1016/j.yexcr.2020.111914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04285
[Journal Article] Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism2019
- Author(s)
  Kazuki Yasuhiro、Kobayashi Kaoru、他23名
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 8 Pages: 3072-3081
- DOI
  10.1073/pnas.1808255116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-18H02367, KAKENHI-PROJECT-18H03974
[Journal Article] Human and mouse artificial chromosome technologies for studies of pharmacokinetics and toxicokinetics2018
- Author(s)
  Satoh Daisuke、Abe Satoshi、Kobayashi Kaoru、Nakajima Yoshihiro、Oshimura Mitsuo、Kazuki Yasuhiro
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 33 Issue: 1 Pages: 17-30
- DOI
  10.1016/j.dmpk.2018.01.002
- NAID
  210000187371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-16H03295, KAKENHI-PROJECT-16K18942
[Journal Article] Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models2017
- Author(s)
  Uno Narumi、Abe Satoshi、Oshimura Mitsuo、Kazuki Yasuhiro
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 2 Pages: 145-156
- DOI
  10.1038/s10038-017-0378-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-15K19615
[Journal Article] Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins.2016
- Author(s)
  Suzuki T, Kazuki Y, Oshimura M, Hara T.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 6 Pages: e0157187-e0157187
- DOI
  10.1371/journal.pone.0157187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-16H04728
[Journal Article] Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans.2016
- Author(s)
  Nakada N, Kawamura A, Kamimura H, Sato K, Kazuki Y, Kakuni M, Ohbuchi M, Kato K, Tateno C, Oshimura M, Usui T.
- Journal Title
  
  Biopharm Drug Dispos.
  
  Volume: 37 Issue: 1 Pages: 3-14
- DOI
  10.1002/bdd.1990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04285
[Journal Article] The effect of supplementation of amino acids and taurine to modified KSOM culture medium on rat embryo development.2016
- Author(s)
  Nakamura K, Morimoto K, Shima K, Yoshimura Y, Kazuki Y, Suzuki O, Matsuda J, Ohbayashi T.
- Journal Title
  
  Theriogenology
  
  Volume: 86 Issue: 8 Pages: 2083-2090
- DOI
  10.1016/j.theriogenology.2016.07.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04285
[Journal Article] Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model.2016
- Author(s)
  Kazuki Y, Akita M, Kobayashi K, Osaki M, Satoh D, Ohta R, Abe S, Takehara S, Kazuki K, Yamazaki H, Kamataki T, Oshimura M.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 21419-21419
- DOI
  10.1038/srep21419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-26460206
[Journal Article] Development of a High-Sensitivity Quantitation Method for Arginine Vasopressin by High-Performance Liquid Chromatography Tandem Mass Spectrometry, and Comparison with Quantitative Values by Radioimmunoassay2016
- Author(s)
  Tsukazaki Y, Senda N, Kubo K, Yamada S, Kugoh H, Kazuki Y, Oshimura M.
- Journal Title
  
  Anal. Sci.
  
  Volume: 32 Issue: 2 Pages: 153-159
- DOI
  10.2116/analsci.32.153
- NAID
  130005125625
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-15K08304
[Journal Article] Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate.2016
- Author(s)
  Hashimoto M, Kobayashi K, Yamazaki M, Kazuki Y, Takehara S, Oshimura M, Chiba K. Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate.
- Journal Title
  
  J Steroid Biochem Mol Biol.
  
  Volume: 163 Pages: 121-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04285
[Journal Article] Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver.2015
- Author(s)
  Kato K, Ohbuchi M, Hamamura S, Ohshita H, Kazuki Y, Oshimura M, Sato K, Nakada N, Kawamura A, Usui T, Kamimura H, Tateno C.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 43 Issue: 8 Pages: 1208-1217
- DOI
  10.1124/dmd.115.063479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04285
[Journal Article] Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans2013
- Author(s)
  Kazuki Y
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 22 Issue: 3 Pages: 578-92
- DOI
  10.1093/hmg/dds468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390040
[Journal Article] Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans2013
- Author(s)
  Kazuki Y, Kobayashi K, Aueviriyavit S, Oshima T, Kuroiwa Y, Tsukazaki Y, Senda N, Kawakami H, Ohtsuki S, Abe S, Takiguchi M, Hoshiya H, Kajitani N, Takehara S, Kubo K, Terasaki T, Chiba K, Tomizuka K, Oshimura M.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 22(3) Pages: 578-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390040
[Journal Article] Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver.2013
- Author(s)
  Hashimoto M, Kobayashi K, Watanabe M, Kazuki Y, Takehara S, Inaba A, Nitta S, Senda N, Oshimura M, Chiba K.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 54 Issue: 8 Pages: 2060-2068
- DOI
  10.1194/jlr.m033464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590170
[Journal Article] Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver2013
- Author(s)
  Hashimoto M, Kobayashi K, Watanabe M, Kazuki Y, Takehara S, Inaba A, Nitta S, Senda N, Oshimura M, Chiba K
- Journal Title
  
  J Lipid Res
  
  Volume: Vol. 54, No. 8 Pages: 2060-2068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590170
[Journal Article] ヒト人工染色体ベクターによる遺伝子細胞治療へ向けて2011
- Author(s)
  香月康宏
- Journal Title
  
  日本臨床
  
  Volume: 69 Pages: 2142-2147
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy2011
- Author(s)
  Tedesco FS, Hoshiya H, D' Antona G, Gerli MF, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M, Cossu G.
- Journal Title
  
  Sci Transl Med
  
  Volume: Volume 3, number 96 Issue: 96 Pages: 96-78
- DOI
  10.1126/scitranslmed.3002342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Refined human artificial chromosome vectors for gene therapy and animal transgenesis.2011
- Author(s)
  Kazuki Y.
- Journal Title
  
  Gene Therapy
  
  Volume: 18 Pages: 384-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models2011
- Author(s)
  Kazuki Y, Oshimura M.
- Journal Title
  
  Mol Ther
  
  Volume: Volume 19, number 9 Issue: 9 Pages: 1591-601
- DOI
  10.1038/mt.2011.136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] ヒト人工染色体ベクターによる遺伝子細胞治療へ向けて2011
- Author(s)
  香月康宏、押村光雄
- Journal Title
  
  日本臨床
  
  Volume: Vol.69, No.12 Pages: 2142-7
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Refined human artificial chromosome vectors for gene therapy and animal transgenesis.2011
- Author(s)
  Kazuki Y.
- Journal Title
  
  Gene Therapy
  
  Volume: 18 Pages: 384-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689010
[Journal Article] 筋ジストロフィー患者由来のiPS細胞における遺伝子修復～ヒト人工染色体ベクターによる新たな遺伝子治療戦略の可能性2010
- Author(s)
  香月康宏
- Journal Title
  
  Medical Bio 7
  
  Pages: 58-63
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Refined human artificial chromosome vectors for gene therapy and animal transgenesis2010
- Author(s)
  Kazuki Y, Hoshiya H, Takiguchi M, Abe S, Iida Y, Osaki M, Katoh M, Hiratsuka M, Shirayoshi Y, Hiramatsu K, Ueno E, Kajitani N, Yoshino T, Kazuki K, Ishihara C, Takehara S, Tsuji S, Ejima F, Toyoda A, Sakaki Y, Larionov V, Kouprina N and Oshimura M
- Journal Title
  
  Gene therapy
  
  Volume: Volume 18, number 4 Issue: 4 Pages: 384-93
- DOI
  10.1038/gt.2010.147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022, KAKENHI-PROJECT-22590301
[Journal Article] Complete genetic correction of iPS cells from Duchenne muscular dystrophy.2010
- Author(s)
  Kazuki Y., Hiratsuka M., Takiguchi M., Osaki M., Kajitani N., Hoshiya H., Hiramatsu K., Yoshino T., Kazuki K., Ishihara C., Takehara S., Higaki K., Nakagawa M., Takahashi K., Yamanaka S., Oshimura M.
- Journal Title
  
  Mol. Therapy. Volume18,number2
  
  Pages: 386-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] ヒト人工染色体ベクターの利点とその応用2010
- Author(s)
  山口繁幸、大林徹也、香月康宏、押村光雄
- Journal Title
  
  生化学
  
  Volume: Vol.82, No.9 Pages: 846-852
- NAID
  10027502606
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Complete genetic correction of iPS cells from Duchenne muscular dystrophy2010
- Author(s)
  Kazuki Y., Hiratsuka M., Takiguchi M., Osaki M., Kajitani N., Hoshiya H., Hiramatsu K., Yoshino T., Kazuki K., Ishihara C., Takehara S., Higaki K., Nakagawa M., Takahashi K., Yamanaka S. and Oshimura M.
- Journal Title
  
  Mol. Therapy
  
  Volume: Volume18, number 2 Issue: 2 Pages: 386-93
- DOI
  10.1038/mt.2009.274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] 筋ジストロフィー患者由来のiPS細胞における遺伝子修復~ヒト人工染色体ベクターによる新たな遺伝子治療戦略の可能性2010
- Author(s)
  香月康宏、押村光雄
- Journal Title
  
  Medical Bio
  
  Volume: Vol.7, No.2 Pages: 58-63
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] ヒト人工染色体ベクターの開発2009
- Author(s)
  香月康宏
- Journal Title
  
  ゲノム医学 9
  
  Pages: 37-40
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Complete genetic correction of iPS cells from Duchenne muscular dystrophy2009
- Author(s)
  Kazuki Y.
- Journal Title
  
  Mol.Therapy 18
  
  Pages: 386-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Complete genetic correction of iPS cells from Duchenne muscular dystrophy2009
- Author(s)
  Kazuki Y.
- Journal Title
  
  Mol.Therapy 18
  
  Pages: 386-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] 幹細胞のゲノム操作:ヒト人工染色体ベクターの開発2009
- Author(s)
  香月康宏、押村光雄
- Journal Title
  
  ゲノム医学
  
  Volume: Vol.9, No.3 Pages: 37-40
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] ヒト人工染色体ベクターの開発2009
- Author(s)
  香月康宏
- Journal Title
  
  ゲノム医学 9
  
  Pages: 37-40
- Data Source
  KAKENHI-PROJECT-21249022
[Journal Article] Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance.2009
- Author(s)
  Kai Y., Wang CC., Kishigami S., Kazuki Y., Abe S., Takiguchi M., Shirayoshi Y., Inoue T., Ito H., Wakayama T., Oshimura M.
- Journal Title
  
  Cell Res. Volume19,number2
  
  Pages: 247-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] 幹細胞のゲノム操作:ヒト人工染色体ベクターの開発2009
- Author(s)
  香月康宏, 押村光雄
- Journal Title
  
  ゲノム医学 Vol.9,No.3
  
  Pages: 37-40
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] A highly stable and non-integrated human artificial chromosome (HAC) containing the 2. 4Mb entire human dystrophin gene.2009
- Author(s)
  Hoshiya H., Kazuki Y., Abe S., Takiguchi M., Kajitani N., Watanabe Y., Yoshino T., Shirayoshi Y., Higaki K., Messina G., Cossu G., Oshimura M.
- Journal Title
  
  Mol. Therapy. Volume17,number2
  
  Pages: 309-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome.2008
- Author(s)
  Kazuki Y, Hoshiy H, Kai Y, Abe S, Takiguch M, Osaki M, Kawazoe S, Katoh M, Kanatsu-Shinohara M, Inoue K, Kajitani N, Yoshino T, Shirayoshi S, Ogura A, Shinohara T, Barrett JC, Oshimura M.
- Journal Title
  
  Gene therapy Volume15,number8
  
  Pages: 617-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector.2008
- Author(s)
  Shitara S, Kakeda M, Nagata K, Hiratsuka M, Sano A, Osawa K, Okazaki A, Katoh M, Kazuki Y, Oshimura M, Tomizuka K.
- Journal Title
  
  Biochem Biophys Res Commun. Volume369,number3
  
  Pages: 807-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Correction of a genetic defect in multipotentGermline stem cells using a human artificial chromosome2008
- Author(s)
  Kazuki Y., Hoshiya H., Kai Y., Abe S., Takiguchi M., Osaki M.,Kawazoe S., Katoh M., Kanatsu-Shinohara M., Inoue K., Kajitani N., Yoshino N., Shirayoshi Y., Ogura A., Shinohara T., BarrettJC., Oshimura M.
- Journal Title
  
  Gene Therapy 15
  
  Pages: 617-24
- Data Source
  KAKENHI-PROJECT-18390107
[Journal Article] A highly stable and non-integrated human artificial chromosome(HAC) containing the 2.4Mb entire human dystrophin gene2008
- Author(s)
  Hoshiya H., Kazuki Y., Abe S., Takiguchi M., Kajitani N., Watanabe Y., Yoshino T.,Shirayoshi Y., Higaki K., Messina G., Cossu G., Oshimura M.,
- Journal Title
  
  Mol. Therapy
- Data Source
  KAKENHI-PROJECT-18390107
[Journal Article] Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector2008
- Author(s)
  Shitara S, Kakeda M, Nagata K, Hiratsuka M, Sano A, Osawa K, Okazaki A, Katoh M, Kazuki Y, Oshimura M, Tomizuka K
- Journal Title
  
  Biochem Biophys Res Commun Volume 369, number 3
  
  Pages: 807-11
- Data Source
  KAKENHI-PROJECT-18390107
[Journal Article] Correction of a genetic defect in multipotent germline stem cell using a human artificial chromosome.2008
- Author(s)
  Kazuki Y
- Journal Title
  
  Gene Ther. 15
  
  Pages: 617-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790246
[Journal Article] Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome.2008
- Author(s)
  Kazuki Y
- Journal Title
  
  Gene Ther. 15
  
  Pages: 617-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390107
[Patent] ヒトの薬物代謝酵素誘導及び薬物動態予測が可能な新規薬物代謝酵素誘導評価方法2016
- Inventor(s)
  香月康宏、阿部智志、押村光雄
- Industrial Property Rights Holder
  鳥取大学、Trans Chromosomics
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-200468
- Filing Date
  2016-10-11
- Data Source
  KAKENHI-PROJECT-15H04285
[Patent] マウス人工染色体ベクター2011
- Inventor(s)
  押村光雄、香月康宏、滝口正人、松岡隆之
- Industrial Property Rights Holder
  押村光雄、香月康宏、滝口正人、松岡隆之
- Filing Date
  2011-01-06
- Overseas
- Data Source
  KAKENHI-PROJECT-22890114
[Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007
- Inventor(s)
  掛田実、富塚一磨、押村光雄、香月康宏
- Industrial Property Rights Holder
  キリンファーマ株式会社
- Filing Date
  2007-07-06
- Overseas
- Data Source
  KAKENHI-PROJECT-18390107
[Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007
- Inventor(s)
  掛田実、富塚一磨、押村光雄、香月康宏
- Industrial Property Rights Holder
  キリンファーマ株式会社
- Filing Date
  2007-07-06
- Overseas
- Data Source
  KAKENHI-PROJECT-19790246
[Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007
- Inventor(s)
  掛田実、富塚一磨、押村光雄、香月康宏
- Filing Date
  2007-07-06
- Overseas
- Data Source
  KAKENHI-PROJECT-18390107
[Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007
- Inventor(s)
  掛田実, 富塚一磨, 押村光雄, 香月康宏
- Industrial Property Rights Holder
  キリンファーマ株式会社
- Filing Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19790246
[Patent] 内在遺伝子を含まないヒト人工染色体ベクター2006
- Inventor(s)
  押村光雄, 香月康宏, 松岡隆之
- Industrial Property Rights Holder
  鳥取大学, 有限株式会社chromocenter
- Industrial Property Number
  2006-127372
- Filing Date
  2006-05-02
- Data Source
  KAKENHI-PROJECT-18390107
[Patent] 内在遺伝子を含まないヒト人工染色体ベクター2006
- Inventor(s)
  押村光雄、香月康宏、松岡隆之
- Industrial Property Number
  2006-127372
- Filing Date
  2006-05-02
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] 染色体工学技術によるヒト化モデル動物・多機能細胞の作製と創薬研究への応用2022
- Author(s)
  香月康宏
- Organizer
  第32回　新薬創製談話会「シン・新薬創製談話会」
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術の開発と応用2022
- Author(s)
  香月康宏
- Organizer
  第5回ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] PXRとCYP3Aを同時にヒト化したラットの薬物間相互作用解析における有用性2022
- Author(s)
  Genki Minegishi, Kaoru Kobayashi, Miyuki Sato, Mayaka Ehara, Kanako Kazuki, Satoshi Abe, Yasuhiro Kazuki
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術によるデザイナー細胞・動物の作製と創薬研究への応用2022
- Author(s)
  香月康宏
- Organizer
  日本遺伝学会第94回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] マウス/ヒト人工染色体によるヒト化動物作製と創薬研究への応用2022
- Author(s)
  香月康宏
- Organizer
  第10回　実験動物科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術によるデザイナー細胞・動物の作製と応用2022
- Author(s)
  香月康宏
- Organizer
  「細胞を創る」研究会 15.0
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 人工染色体技術によるデザイナー細胞・動物の作製とゲノム動作原理の解明2021
- Author(s)
  香月康宏
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術によるヒト化モデル動物・多機能細胞の作製と創薬研究への応用2021
- Author(s)
  香月康宏
- Organizer
  第4回医薬品毒性機序研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] マウス/ヒト人工染色体によるヒト化モデル動物の作製と創薬研究への応用2021
- Author(s)
  香月康宏
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] ヒト/マウス人工染色体によるデザイナー細胞・動物の作製と創薬研究への応用2021
- Author(s)
  香月康宏
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術応用（14）：機能ペプチドの表現型スクリーニングを行う多様化誘導型発現細胞ライブラリの開発2021
- Author(s)
  円子大夢、奥山優希、橋本七海、宇野愛海、石津由紀、香月康宏、堀田秋津、冨塚一磨
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H02924
[Presentation] Application for drug discovery using mammalian artificial chromosomes and genome editing technology2021
- Author(s)
  香月康宏
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術応用（13）：抗体の表現型スクリーニングを可能にする、多様化誘導型抗体発現細胞ライブラリの開発2021
- Author(s)
  橋本七海、笹川航、宇野愛海、里深博幸、香月康宏、堀田秋津、冨塚一磨
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H02924
[Presentation] マウス人工染色体とゲノム編集によるヒト化モデル動物の作製と創薬研究への応用2021
- Author(s)
  香月康宏
- Organizer
  第68回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 染色体工学技術の創薬研究への応用2020
- Author(s)
  香月康宏
- Organizer
  東京大学　薬学部大学院セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 人工染色体を用いたデザイン細胞・動物の創成2020
- Author(s)
  香月康宏
- Organizer
  第3回ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 人工染色体技術を用いた創薬研究への応用2020
- Author(s)
  香月康宏
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 人工染色体技術によるデザイナー細胞・動物の作製と創薬研究への応用2020
- Author(s)
  香月康宏
- Organizer
  令和２年度BINDS公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03173
[Presentation] 人工染色体技術を用いた創薬研究への応用2019
- Author(s)
  香月康宏
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 人工染色体技術を用いた創薬研究への応用2019
- Author(s)
  香月康宏
- Organizer
  平成30年度HTS バイオ分子設計研究会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] ヒト/マウス人工染色体を用いたゲノムライティングと応用2019
- Author(s)
  香月康宏
- Organizer
  第８回ExCELLSセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 人工染色体技術を用いた創薬研究への応用2019
- Author(s)
  香月康宏
- Organizer
  第20回日本毒性病理学会・教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 人工染色体技術を用いた創薬研究への応用2019
- Author(s)
  香月康宏
- Organizer
  第１回医薬品毒性機序研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 人工染色体技術によるデザイン染色体の構築2019
- Author(s)
  香月康宏
- Organizer
  「デザイン細胞医薬」ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 最先端染色体工学技術の創薬研究への応用2018
- Author(s)
  香月康宏
- Organizer
  平成30年度　内外環境・代謝酵素研究会
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 最先端染色体工学技術の創薬研究への応用2017
- Author(s)
  香月康宏
- Organizer
  薬物動態談話会第40年回
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] ヒト薬物代謝予測のためのマウス人工染色体とゲノム編集によるヒト化CYP3Aラットの作製2016
- Author(s)
  香月康宏
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  キッセイ文化ホール/松本市総合体育館（長野県松本市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 染色体工学技術によるヒト化動物の作製と医学・薬学応用2016
- Author(s)
  香月康宏
- Organizer
  第23回HAB研究機構学術年会
- Place of Presentation
  つくば産業技術総合研究所（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 染色体工学技術によるヒト化動物の作製と医学・薬学応用2016
- Author(s)
  香月康宏
- Organizer
  第23回HAB研究機構学術年会
- Place of Presentation
  つくば産業技術総合研究所（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-PROJECT-26640059
[Presentation] 染色体工学技術を用いた新規トランスクロモソミック動物作製システムの開発2015
- Author(s)
  香月康宏
- Organizer
  日本実験動物学会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H04285
[Presentation] 染色体工学技術によるヒト化モデル動物作製法の開発と応用2015
- Author(s)
  香月康宏
- Organizer
  ゲノム編集マウスワークショップ
- Place of Presentation
  理化学研究所バイオリソースセンター（茨城県つくば市）
- Year and Date
  2015-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-26640059
[Presentation] 染色体工学技術を用いた新規トランスクロモソミック動物作製システムの開発2015
- Author(s)
  香月康宏
- Organizer
  日本実験動物学会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-26640059
[Presentation] Sex-dependent Diffirences of CYP3A4 Expression in CYP3A-HAC Mice2012
- Author(s)
  遠藤美佳、渡邊未央、小林カオル、香月康宏、山崎由貴、嵩原昇子、押村光雄、千葉　寛
- Organizer
  50th Anniversary Symposium On Cytochrome P450
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590170
[Presentation] エストロゲンによる肝CYP3A4発現誘導メカニズム2012
- Author(s)
  遠藤美佳、小林カオル、山崎由貴、稲葉明日実、阿部千尋、香月康宏、嵩原昇子、押村光雄、千葉寛
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590170
[Presentation] Sex-dependent Diffirences of CYP3A4 Expression in CYP3A-HAC Mice2012
- Author(s)
  Mika Endo, Mio Watanabe, Kaoru Kobayashi, Yasuhiro Kazuki, Yuki Yamasaki,Shoko Takehara, Mitsuo Oshimura, and Kan Chiba
- Organizer
  50th Anniversary Symposium On Cytochrome P450
- Place of Presentation
  FUKUOKA, JAPAN
- Data Source
  KAKENHI-PROJECT-23590170
[Presentation] 遺伝子再生医療・ヒト型モデル動物作製のためのヒト人工染色体ベクター(HAC)システムの開発2011
- Author(s)
  香月康宏
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-22689010
[Presentation] Novel human artificial chromosome vector for gene delivery2011
- Author(s)
  Kazuki Y
- Organizer
  第34回分生生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] Development of a high-sensitivity toxicity test system using chromosome engineering and bioluminescence technology2011
- Author(s)
  T. Nishida, Y. Yoshimura, K. Sasaki, Y. Nakajima, R. Saito, Y. Kazuki, S. Nishii, Y. Ohmiya, S. Aiba, M. Oshimura and T. Ohbayashi
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22890114
[Presentation] Humanized model mice containing P-450-related genes using a novel mouse artificial chromosome2011
- Author(s)
  Kazuki, et al.
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21390040
[Presentation] ヒト人工染色体ベクターを用いて作製したCYP3A-HACマウスにおけるヒトCYP3A4発現の性差2011
- Author(s)
  遠藤美佳、渡邉未央、小林カオル、香月康宏、山﨑由貴、嵩原昇子、押村光雄、千葉寛
- Organizer
  日本薬物動態学会第26回年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23590170
[Presentation] 遺伝子再生医療・ヒト型モデル動物作製のためのヒト人工染色体ベクター(HAC)システムの開発2011
- Author(s)
  香月康宏
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] ジストロフィン2.4Mb搭載ヒト人工染色体による筋ジストロフィー由来iPS細胞の遺伝子完全修復2010
- Author(s)
  香月康宏
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] ジストロフィン2. 4Mb搭載ヒト人工染色体による筋ジストロフィー由来iPS細胞の遺伝子完全修復2010
- Author(s)
  香月康宏
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] (2) FUNCTIONAL EXPRESSION OF HUMAN CYP3A ISOFORMS IN CYP3A-HAC MICE AND INHIBITION OF CYP3A VIA MECHHANISM -BASED INACTIVATION(ポスター発表) 9th Interntional ISSX Meeting ・Istanbul Turkey・2010
- Author(s)
  Mio Watanabe, Sasitorn Aueviriyavit, Kaoru Kobayashi, Nahoko Iuchi, Yasuhiro kazuki,Mitsuo Oshimura and Kan Chiba HUMANIZED CYP3A MICE
- Data Source
  KAKENHI-PROJECT-21390040
[Presentation] Correction of Duchenne muscular dystrophy in induced pluripotent stem cells using a human artificial chromosome2009
- Author(s)
  Kazuki Y
- Organizer
  ASHG 59^<th> annual meeting
- Place of Presentation
  USA.ハワイ
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] ヒト型P450薬物代謝酵素発現マウス2009
- Author(s)
  香月康宏, 小林カオル, 千葉寛, 押村光雄
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] 染色体工学技術を用いたヒト型モデル動物の作製と応用2009
- Author(s)
  香月康宏
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] Correction of Duchenne muscular dystrophy in induced pluripotent stem cells using a human artificial chromosome2009
- Author(s)
  Kazuki Y
- Organizer
  ASHG 59th annual meeting
- Place of Presentation
  USA、ハワイ
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21249022
[Presentation] 染色体工学技術を用いたヒト型モデル動物の作製と応用2009
- Author(s)
  香月康宏
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] 染色体工学技術を用いたヒト型モデル動物の作製と応用2009
- Author(s)
  香月康宏, 押村光雄
- Organizer
  第129回日本薬物学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] 多能性精原幹細胞(mGS)とヒト人工染色体ベクターを用いた欠損型遺伝子治療を目指して2008
- Author(s)
  阿部智志、香月康宏、星谷英寿、甲斐義輝、滝口正人、尾崎克彦、川添真史郎、加藤基伸、篠原美都、井上貴美子、梶谷尚世、吉野とう子、白吉安昭、小倉淳郎、篠原隆司、押村光雄
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] A novel human artificial chromosome (HAC) for gene therapy and animal transgenesis2008
- Author(s)
  Kazuki Y., Hoshiya H., Abe S., Takiguchi M., Iida Y., Watanabe Y., Osaki M., Katoh M., Kajitani N., Yoshino T., Shirayoshi Y., Hiratsuka M., Kurimasa K., Oshimura M.
- Organizer
  ASGT 11th annual meeting
- Place of Presentation
  U.S.A.
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] A novel human artificial chromosome (HAC) for gene therapy and animal transgenesis2008
- Author(s)
  Kazuki Y., Hoshiya H., Abe S., Takiguchi M., Iida Y., Watanabe Y., Osaki M., Katoh M., Kajitani N., Yoshino T., Shirayoshi Y., Hiratsuka M., Kurimasa K., and Oshimura M.
- Organizer
  ASGT 11th annual meeting
- Place of Presentation
  U.S.A.
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] ジストロフィンゲノムDNA(2.5Mb)を搭載したHAC ベクター : 遺伝子治療を目指して2008
- Author(s)
  星谷英寿、香月康宏、甲斐義輝、阿部智志、滝口正人、飯田雄一 ,渡辺義徳, 尾崎克彦、梶谷尚世,吉野とう子,白吉安昭 ,押村光雄
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] A novel human artificial chromosome (HAC)for gene therapy and animal transgenesis2008
- Author(s)
  Kazuki Y
- Organizer
  ASGT 11^<th> annual meeting
- Place of Presentation
  USA, Boston
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] A human artificial chromosome (HAC) vector with about 2.4 Mb-human Dystrophin genome including native expression control elements2008
- Author(s)
  Hoshiya H., Kazuki Y., Abe S., Kai Y., Takiguchi M., Iida Y., Watanabe Y., Osaki M., Kajitani N., Yoshino T., Shirayoshi Y. and Oshimura M.
- Organizer
  ASGT 11^<th> annual meeting
- Place of Presentation
  U.S.A.
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] 遺伝子治療に向けた新規遺伝子治療用ヒト人工染色体ベクターの開発2008
- Author(s)
  香月康宏, 星谷英寿, 甲斐義輝, 阿部智志, 滝口正人, 飯田雄一, 渡辺義徳, 尾崎克彦, 梶谷尚世, 吉野とう子, 白吉安昭, 富松望, 平塚正治, 栗政明弘, 押村光雄
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] A novel human artificial chromosome (HAC) for gene therapy and animal transgenesisASGT 11^<th> annual meeting2008
- Author(s)
  Kazuki Y
- Organizer
  ASGT 11^<th> annual meeting
- Place of Presentation
  USA, Boston
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] 新規ヒト人工染色体ベクターの構築 : サブテロメアを用いた高発現ベクター系2008
- Author(s)
  掛田実、永田恵子、佐野暁子、大澤加奈子、岡崎晃代、設楽真吾、香月康宏、押村光雄、富塚一磨
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] 遺伝子治療に向けた新規遺伝子治療用ヒト人工染色体ベクターの開発2008
- Author(s)
  香月康宏, 星谷英寿, 甲斐義輝, 阿部智志, 滝口正人, 飯田雄一, 渡辺義徳, 尾崎克彦, 梶谷尚世, 吉野とう子, 白吉安昭, 富松望, 平塚正治, 栗政明弘, 押村光雄
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] Genetic restoration of ataxia telangiectasia cells using a human artificial chromosome mediated- genomic cloning system2007
- Author(s)
  Kazuki Y
- Organizer
  ASGT 10th annual meeting
- Place of Presentation
  USA,Seattle
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] Genetic restoration of ataxia telangiectasia cells using a human artificial chromosome mediatedgenomic cloning system2007
- Author(s)
  Kazuki Y., Hoshiya, H., Kai Y., Abe S., Takiguchi M., Osaki M., Yuichi I., Mizutani E., Kajitani N., Yoshino T., Shirayoshi Y., Tomimatsu N., Hratsuka M., Kurimasa A., Wakayama T., Oshimura, M.
- Organizer
  ASGT 10th annual meeting
- Place of Presentation
  U.S.A.
- Data Source
  KAKENHI-PROJECT-19790246
[Presentation] Genetic restoration of ataxia telangiectasia cells using a human artificial chromosome mediated-genomic cloning system2007
- Author(s)
  Kazuki Y
- Organizer
  ASGT 10th annual meeting
- Place of Presentation
  USA
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] Functional restoration of a genetic defect in multipotent germline stem cells by human artificial chromosome containing a genomic insert2006
- Author(s)
  Kazuki Y., Hoshiya, H., Kai Y., Abe S., Takiguchi M., Osaki M., Kanatsu-Shinohara M., Kajitani N., ShirayoshiY., Hratsuka M., Ogura A., Shinohara T.and Oshimura, M
- Organizer
  ASGT 9^<th> annual meeting
- Place of Presentation
  U.S.A.
- Data Source
  KAKENHI-PROJECT-18390107
[Presentation] ヒト人工染色体ベクターを用いて作製したCYP3A-HACマウスにおけるヒトCYP3A4発現の性差
- Author(s)
  遠藤美佳、渡邉未央、小林カオル、香月康宏、山崎由貴、嵩原昇子、押村光雄、千葉　寛
- Organizer
  日本薬物動態学会第26回年会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-23590170

1. OSHIMURA Mitsuo (20111619)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. CHIBA Kan (40159033)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. KOBAYASHI Kaoru (30255864)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. FURIHATA Tomomi (80401008)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TOMIZUKA KAZUMA (40444640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 平林真澄 (20353435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 堀田秋津 (50578002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. KATO Motonobu (00273904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. OSAKI Mitsuhiko (40325006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. NISHIDA Tadashi (50588556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. OHBAYASHI Tetsuya (80348804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. IMAI Teruko (70176478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HOSOKAWA Masakiyo (70181500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OTOI Takeshige (30311814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 竹本龍也 (30443899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 谷原史倫 (90754680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 濱道修生 (60721686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 西川結梨 (40940929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 武中篤 (50368669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAZUKI Yasuhiro 香月 康宏

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完全ヒト抗体産生ウサギ作製によるゲノム動作原理解明および高機能抗体取得の試みPrincipal Investigator

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Generation of humanized rats expressing multiple drug-metabolizing enzyme-related genes using mammalian artificial chromosome technologiesPrincipal Investigator

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Generation of humanized rats expressing drug-metabolizing enzyme using human artificial chromosome and genome editing technologiesPrincipal Investigator

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Development of rapid system for generation of consomic mice via chromosome transfer and elimination technologiesPrincipal Investigator

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iPS細胞とヒト人工染色体ベクターを用いた毛細血管拡張性運動失調症の遺伝子治療Principal Investigator

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KAZUKI Yasuhiro 香月康宏

[Book] 進化するゲノム編集技術、真下知士　城石俊彦　監修2015