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Fujita Toshiro  藤田 敏郎

… Alternative Names

TOSHIRO Fujita  藤田 敏郎

FUJITA Toshiro  藤田 敏郎

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Researcher Number 10114125
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9141-7060
Affiliation (Current) 2025: 東京大学, 先端科学技術研究センター, 名誉教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 東京大学, 先端科学技術研究センター, 名誉教授
2019 – 2020: 東京大学, 先端科学技術研究センター, 名誉教授・先端研フェロー
2015 – 2017: 東京大学, 先端科学技術研究センター, 特任研究員、名誉教授
2014 – 2017: 東京大学, 先端科学技術研究センター, 特任研究員
2016: 東京大学, 先端科学技術研究所, 特任教授 … More
2015: 東京大学, 先端科学技術研究センター, 特任研究員・名誉教授
2015: 東京大学, 先端科学技術研究センター, 研究員
2015: 東京大学, 先端科学技術研究センター, 研究員、名誉教授
2015: 東京大学, 先端科学技術研究センター, 教授
2014: 東京大学, 先端研, 特任教授
2013: 東京大学, 先端科学技術研究センター, 特任研究員、名誉教授
2012: 東京大学, 先端科学技術研究センター, 教授
2009 – 2011: The University of Tokyo, 医学部附属病院, 教授
2007 – 2008: The University of Tokyo, Faculty of Medicine, Professor
2002 – 2007: UNIV. OF TOKYO, SCHOOL OF MEDICINE., PROFESSOR, 医学部附属病院, 教授
2003: 東京大学, 医学系研究科, 教授
2002 – 2003: 東京大学, 大学院・医学系研究科, 教授
2002: Univ. of Tokyo, School of Medicine, Professor, 医学部附属病院, 教授
2002: 東京大学, 医学部, 教授
2001: Tokyo Univ., Dept. of Medicine Prof., 医学部・附属病院, 教授
1998 – 2001: 東京大学, 医学部(分), 教授
2000: 東京大学, 医学部, 教授
1998 – 2000: 東京大学, 医学部・附属病院分院, 教授
1991 – 1994: 東京大学, 医学部(分), 助教授
1991: 東京大学, 医学部・(分), 助教授
1989: 東京大学, 医学部(分), 助教授
1988: 東京大学, 医学部第四内科, 講師
1987: Assistant Professor, Institute of Clinical Medicine, 臨床医学系, 講師
1986: 筑大, 臨床医学系, 講師 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Circulatory organs internal medicine / Endocrinology / Medium-sized Section 53:Organ-based internal medicine and related fields / 内分泌・代謝学 / Kidney internal medicine / Biological Sciences
Except Principal Investigator
Kidney internal medicine / Circulatory organs internal medicine / Endocrinology … More / Biological Sciences / Molecular biology / Urology / Circulatory organs internal medicine Less
Keywords
Principal Investigator
高血圧 / エピジェネティクス / 酸化ストレス / 腎障害 / 食塩 / 食塩感受性高血圧 / ミネラルコルチコイド / DNAメチル化 / 糖尿病性腎症 / アルドステロン … More / LOX-1 / 臓器障害 / 内科 / Hypertension / TGFβ / hypertension / アドレノメデュリン / アンジオテンシンII / メタボリックシンドローム / 鉱質コルチコイド受容体 / 交感神経 / タウリン / 動脈硬化 / 血圧 / ノックアウトマウス / 血管障害 / 生活習慣病 / 血管拡張物質 / 尿中マーカー / 近位尿細管 / 集合管 / ナノキャリア / 高血圧学 / コルチゾール / DOHaD / ミネラルコルチコイド受容体 / 加齢 / 糖尿病性腎臓病 / 腎臓病 / 環境因子 / 糖質コルチコイド / 鉱質コルチコイド / ミネラロコルチコイド受容体 / 酸塩基異常 / ペンドリン / 遠位尿細管 / opioid peptide / taurine / DOCA-salt高血圧ラット / ナロキソン / 交換神経系 / オピオイドペプチド / adrenomedullin / salt / inflammation / aldosterone / Metabolic syndrome / Organ regeneration / Oxidative stress / 脂肪細胞 / 遺伝子変異 / 炎症 / 臓器再生 / Renal Intestitial / Oxidative Stress / Atherosclerosis / Angiotensin II / Renal Damage / transgenic rat / mineralocorticoid / Salt / Nephrosclerosis / Kidney / tie2 / flk-1 / Diahetes / Redox / PRARγ / Dahl Rat / oxidized LDL / 腎間質 / organ damage / knockout mice / oxidative stress / insulin resistance / vasodilating agent / 血管平滑筋 / 心肥大 / インスリン抵抗性 / angiotensin II / sympathetic nervous system / vascular reactivity / vascular endothelial cells / vascular smooth muscle cells / magnesium / ノルエピネフリン / 平滑筋細胞 / 内皮細胞 / バロファンクション / 中枢神経系 / 内皮依存性弛緩因子 / 交感神経系 / 血管反応性 / 血管平滑筋細胞 / 血管内皮細胞 / マグネシウム / 心拍出量 / ストレス / 腎臓 / エピゲノム / 糖尿病 / 肥満糖尿病マウス / アルドステロン分泌刺激因子 / 心腎連関 / Racl / ポドサイト / 酸化的ストレス / Rac1 / 核内受容体 / サイトカイン / TNFα / PPARγ / 遺伝子改変動物 / 抗酸化物質 / peroxisome proliferator-activated receptor γ / レクチン様酸化LDL受容体-1(LOX-1) / 酸化低比重リポ蛋白(LDL) / 血管拡張物資 … More
Except Principal Investigator
G蛋白質病 / 分子機構 / レセプター / G蛋白質 / iPS細胞 / 再生医学 / 遺伝子治療 / 高血圧 / 核内受容体 / G PROTEIN DISEASE / MOLECULAR MECHANISM / G PROTEIN / SNPs / 動脈硬化 / PAMP / 再生医療 / メチル化 / HDAC阻害剤 / 腎臓由来iPS細胞 / 慢性腎臓病 / 心不全 / インバースアゴニスト / 心肥大 / 脱感作 / 塩化アンモニウム / スーパーオキサイド / JMJD1A / UCP1 / 褐色脂肪細胞 / ホスファターゼ / 寒冷 / アドレナリン受容体 / Pparg / クロマチン / 糖脂質代謝 / エピジェネティクス / クロマチン再構成 / 褐色脂肪 / 熱産生 / JMJD1A / ヒストン脱メチル化酵素 / クロマチン構造 / エピゲノム / 初期化 / 包括的DNAメチル化解析 / 腎臓再生 / iPS細胞移植 / エピジェネティックス / 腎臓細胞記憶 / DNAメチル化解析 / Epigenetics / 新規腎臓発生・再生因子 / 網羅的マイクロアレイ解析 / 包括的メチル化解析 / 腎系統特異的分化誘導法 / Epigenetic Memory / 電解質調節 / ミネラロコルチコイド受容体 / 体液恒常性 / ユビキチンリガーゼ / 翻訳後修飾 / 電解質異常 / 膜輸送体 / ユビキチン・プロテアソーム系 / リン酸化 / tumor necrosis factor-α (TNFα) / PPARγ knockout mice / lpr mice / atherosclerosis / peroxisome proliferator-activated receptor-γ (PPARγ) / thiazolidinediones / cytokine / lectin-like oxidized LDL receptor-1 (LOX-1) / タウリン / 酸化ストレス / 腎障害 / PPARγ / LOX-1 / TNAα / lprマウス / TNFα / PPARγノックアウトマウス / 1prマウス / peroxisome proliferator-activated receptor-γ(PPARγ) / チアゾリジン誘導体 / サイトカイン / レクチン様酸化LDL受容体-1(LOX-1) / INVERSE AGONIST / CARDIOMEGALY / DESENSITIZATION / GENE THERAPY / RECEPTOR / G PROTEIN-COUPLED RECEPTOR / Gene therapy / G protein disease / Molecular Medianism / Receptor / G protein / haplotype association study / haplotype / susceptible genes / essential hypertension / 連鎖不平衡 / ガイドライン / DOP-PCR / 本能性高血圧 / ゲノムワイド / 発症関連遺伝子 / LDブロック / 関連解析 / ハプロタイプ / ハプロタイプ関連解析 / ハプロタイプ解析 / 感受性遺伝子 / 本態性高血圧 / knockout mouse / transgenic animal / receptor / pathophysiology / circulation control / biologically active peptide / adrenomedullin / C末端アミド化 / 血管作動性ペプチド / 循環調節因子 / ラジオイムノアッセイ / AMシンポジウム / AM遺伝子 / 生合成機構 / 生体内制御機構 / 循環調節機構 / アドレノメデュリン遺伝子 / 降圧ペプチド / 探索医療 / モノクローナル抗体 / 循環器疾患 / ノックアウト動物 / トランスジェニック動物 / 受容体 / 病態生理 / 循環調節 / 生理活性ペプチド / アドレノメデュリン / 再生 / 腎臓 / iPS 細胞 / マイクロアレイ / iPS cells / 幹細胞 / 特異的分化 / siRNA Knockdown処置 / 皮膚線維芽細胞由来iPS細胞 / TSA処置(HDAC阻害剤) / 線維芽細胞由来iPS細胞 / 腎臓上皮細胞由来iPS細胞 / 腎上皮由来iPS細胞 / エピジェネティク・メモリー / siRNA Knockdown / NF-kappaB / Sgk1 / メタボリックシンドローム / 鉱質コルチコイド受容体 / Rac1 / 糸球体足細胞 / Racl / アルドステロン / 糸球体足細胞障害 / 生活習慣病 / マイクロドメイン / 循環器・高血圧 / 細胞生物学 / 内皮機能 / イメージング / シグナル伝達 / 幼若高血圧自然発症ラット / 内皮細胞 / 食塩感受性高血圧 / 細胞内pH / トロボキサンA_2 / 細胞内アルカリ化 / 内皮依存性弛緩因子 / ラット / アンジオテンシンII / 交感神経系 / 食塩 / カルシウム Less
  • Research Projects

    (35 results)
  • Research Products

    (477 results)
  • Co-Researchers

    (57 People)
  •  Integrative elucidation of lifestyle diseases using the epigenomic memory of kidney cellsPrincipal Investigator

    • Principal Investigator
      Fujita Toshiro
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  Development of a new treatment for diabetic nephropathy by siRNA delivery using nanocarriersPrincipal Investigator

    • Principal Investigator
      Toshiro Fujita
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  Exploration of gluco- and mineralocorticoid-dependent sodium transporter system involved in salt sensitive hypertensionPrincipal Investigator

    • Principal Investigator
      Fujita Toshiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  生活習慣病の高血圧/臓器障害における糖質・鉱質コルチコイドの役割と新規治療探索Principal Investigator

    • Principal Investigator
      藤田 敏郎
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseases

    • Principal Investigator
      Shibata Shigeru
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Teikyo University
  •  Development of a novel strategy for life style disease through exploration of the roles of mineral- and gluco-corticoids in hypertension and organ dysfunctionPrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Exploration of epigenome abnormalities involved in salt sensitive hypertensionPrincipal Investigator

    • Principal Investigator
      Fujita Toshiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Search for novel therapeutic target molecules focusing on cellular memory in iPS conversion of human kidney cancer cells

    • Principal Investigator
      idei mana
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      The University of Tokyo
  •  Establishment of a specific differentiation induction method to the kidneys constituent cells using a cell memory of the human kidney-derived iPS cells

    • Principal Investigator
      TAKASE OSAMU
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  The function of histone demethylase JMJD1A as a signal-sensing scaffold

    • Principal Investigator
      INAGAKI TAKESHI
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Gunma University
      The University of Tokyo
  •  Epigenetic mechanisms underlying renal derangement in hypertension and diabetesPrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Artifical kidney established by human kidney derived iPS cells

    • Principal Investigator
      HISHIKAWA Keiichi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  New cell therapy for kidney disease using human kidney derived iPS cells

    • Principal Investigator
      YOSHIKAWA Masahiro
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of new renal regenerative therapy using human Renal-iPScells regulated by NF-kappaB

    • Principal Investigator
      TAKASE Osamu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  The mechanism for activation of aldosterone/mineralocorticoid receptor in life style-related diseasesPrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Strategy for overcoming chronic kidney disease, focusing on mineralocorticoid receptor

    • Principal Investigator
      NAGASE Miki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  Mechanisms and physiology of Ca^<2+> influx by spatial regulation ofcaveolae in endothelial cells

    • Principal Investigator
      ISSHIKI Masashi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Targeting oxidative stress and new therapy in metabolic syndromePrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  遺伝子工学を用いた動脈硬化形成とその防御機構の解析―LOX-1とPPARγの役割Principal Investigator

    • Principal Investigator
      藤田 敏郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  G PROTEIN AND DISEASES : ANALYSES OF MOLECULAR MECHANISMS AND REGULATION OF SIGNALS

    • Principal Investigator
      IIRI Taroh
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Endocrinology
    • Research Institution
      The UNIVERSITY OF TOKYO
  •  Role of LOX-1 and protective effect of PPARγ in the development of atherosclerosis

    • Principal Investigator
      ANDO Katsuyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  METHOD TO ANALYZE RECEPTOR-G PROTEIN INTERACTION

    • Principal Investigator
      IIRI Taroh
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  G蛋白質病と疾患:分子機構の解析とシグナル

    • Principal Investigator
      IIRI Taroh
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  発生工学を用いた食塩感受性高血圧発症機序及び臓器障害進展の研究Principal Investigator

    • Principal Investigator
      藤田 敏郎
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Identification of susceptible genes for essential hypertension

    • Principal Investigator
      HATA Akira
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Graduate School of Medicine, Chiba university
      Asahikawa Medical College
  •  Role of oxidized LDL/LOX-1 in the development and progression of renal disease.Principal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  G protein diseases : analysis and application

    • Principal Investigator
      IIRI Taroh
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  The study of physiological and pathophysiological roles of adrenomedullin and related peptides.

    • Principal Investigator
      ETO Tanenao
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Miyazaki Medical College
  •  PHYSIOLOGICAL ROLE OF ADRENOMEDULLIN BY MOLECULAR BIOLOGICAL AND GENE ENGINEERING APPROACHPrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      UNIVERSITY OF TOKYO
  •  食塩感受性高血圧におけるNa-Hantiportの役割

    • Principal Investigator
      安東 克之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  食塩高血圧の昇圧機序における細胞内pHの役割:特に内皮細胞機能について

    • Principal Investigator
      安東 克之
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  アンジオテンシンIIー食塩高血圧ラットにおけるカルシウムの降圧効果

    • Principal Investigator
      ANDO Katsuyuki
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Multiple mechanisms for vasodilator effect of magnesiumPrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  高血圧の発症機序における食塩とストレスの関連に関する研究Principal Investigator

    • Principal Investigator
      藤田 敏郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Role of endogenous opioid peptide in the hypotensive action of taurinePrincipal Investigator

    • Principal Investigator
      FUJITA Toshiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tsukuba

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All Journal Article Presentation Book Patent Other

  • [Book] Hypertension: A Companion to Braunwald's Heart Disease, 3rd Edition, Edited by George L. Bakris、Matthew Sorrentino Chapter 24 “Renin Angiotensin Aldosterone System Blockers”2017

    • Author(s)
      Shibata S, Fujita T
    • Publisher
      ELSEVIER
    • ISBN
      9780323429733
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Book] Bakris: Hypertension, 3e2016

    • Author(s)
      Shigeru Shibata, Toshiro Fujita
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-15H04837
  • [Book] Angiotensinogen as an adipokine in "Modern Insights Into Disease From Molecules to Man : Adipokines (edited by Victor R Preedy)"2011

    • Author(s)
      Miki Nagase, Toshiro Fujita
    • Publisher
      SCIENCE PUBLISHERS
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Book] Angiotensinogen as an adipokine2011

    • Author(s)
      Nagase M, Fujita T.
    • Publisher
      Science Publishers
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Book] Hypertension and obesity2009

    • Author(s)
      Nagase M, Fujita T.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Prostacyclin analog beraprost sodium efficacy in primary glomerular disease or nephrosclerosis: Analysis of the Japanese subgroup in CASSIOPEIR study2021

    • Author(s)
      Kurumatani Hajimu、Okada Kiyonobu、Origasa Hideki、Fujita Toshiro、Isono Masanao、Nakamoto Hidetomo
    • Journal Title

      Therapeutic Apheresis and Dialysis

      Volume: - Issue: 5 Pages: 551-564

    • DOI

      10.1111/1744-9987.13616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Journal Article] Role of Rho in Salt-Sensitive Hypertension2021

    • Author(s)
      Kawarazaki Wakako、Fujita Toshiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 6 Pages: 2958-2958

    • DOI

      10.3390/ijms22062958

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-18K08028, KAKENHI-PROJECT-20K21596
  • [Journal Article] Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice.2021

    • Author(s)
      Hirohama D, Nishimoto M, Ayuzawa N, Kawarazaki W, Fujii W, Oba S, Shibata S, Marumo T, Fujita T.
    • Journal Title

      Hypertension

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Journal Article] The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury2021

    • Author(s)
      Ayuzawa Nobuhiro, Fujita Toshiro
    • Journal Title

      Journal of the American Society of Nephrology

      Volume: 32 Issue: 2 Pages: 279-289

    • DOI

      10.1681/asn.2020071041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08585, KAKENHI-PROJECT-20K21596, KAKENHI-PROJECT-15H05788
  • [Journal Article] Kidney and epigenetic mechanisms of salt-sensitive hypertension.2021

    • Author(s)
      Kawarazaki W, Fujita T.
    • Journal Title

      Nat Rev Nephrol.

      Volume: 17 Issue: 5 Pages: 350-363

    • DOI

      10.1038/s41581-021-00399-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21596, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-18K08028
  • [Journal Article] Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents2020

    • Author(s)
      Wang Conghui、Kawakami-Mori Fumiko、Kang Lei、Ayuzawa Nobuhiro、Ogura Sayoko、Koid Suang Suang、Reheman Latapati、Yeerbolati Alimila、Liu Beibei、Yatomi Yutaka、Chen Xiangmei、Fujita Toshiro、Shimosawa Tatsuo
    • Journal Title

      Kidney International

      Volume: 98 Issue: 5 Pages: 1242-1252

    • DOI

      10.1016/j.kint.2020.05.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Journal Article] Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency2020

    • Author(s)
      Kawarazaki W, Mizuno R, Nishimoto M, Ayuzawa N, Hirohama D, Ueda K, Kawakami-Mori F, Oba S, Marumo T and Fujita. T.
    • Journal Title

      J Clin Invest

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Journal Article] Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency2020

    • Author(s)
      Kawarazaki Wakako、Mizuno Risuke、Nishimoto Mitsuhiro、Ayuzawa Nobuhiro、Hirohama Daigoro、Ueda Kohei、Kawakami-Mori Fumiko、Oba Shigeyoshi、Marumo Takeshi、Fujita Toshiro
    • Journal Title

      Journal of Clinical Investigation

      Volume: 130 Pages: 4152-4166

    • DOI

      10.1172/jci134431

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08672, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-18K08028, KAKENHI-PROJECT-19K22984
  • [Journal Article] Podocyte Injury Augments Intrarenal Angiotensin II Generation and Sodium Retention in a Megalin-Dependent Manner2019

    • Author(s)
      Koizumi Masahiro、Ueda Kohei、Niimura Fumio、Nishiyama Akira、Yanagita Motoko、Saito Akihiko、Pastan Ira、Fujita Toshiro、Fukagawa Masafumi、Matsusaka Taiji
    • Journal Title

      Hypertension

      Volume: 74 Issue: 3 Pages: 509-517

    • DOI

      10.1161/hypertensionaha.118.12352

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08254, KAKENHI-PROJECT-19K22628, KAKENHI-PROJECT-18H02827, KAKENHI-PROJECT-17K16100, KAKENHI-PROJECT-15H05788
  • [Journal Article] Stromal Interaction Molecule 1 modulates blood pressure via NO production in vascular endothelial cells2018

    • Author(s)
      Nishimoto M, Mizuno R, Fujita T, Isshiki M
    • Journal Title

      Hypertens Res in press

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Journal Article] Stromal Interaction Molecule 1 modulates blood pressure via NO production in vascular endothelial cells2018

    • Author(s)
      Nishimoto M, Mizuno R, Fujita T, Isshiki M
    • Journal Title

      Hypertens Res in press

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Journal Article] Stromal interaction molecule 1 modulates blood pressure via NO production in vascular endothelial cells2018

    • Author(s)
      Nishimoto Mitsuhiro、Mizuno Risuke、Fujita Toshiro、Isshiki Masashi
    • Journal Title

      Hypertension Research

      Volume: 41 Issue: 7 Pages: 506-514

    • DOI

      10.1038/s41440-018-0045-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Journal Article] Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension2017

    • Author(s)
      Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, and Toshiro Fujita
    • Journal Title

      Hypertension

      Volume: -

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Journal Article] Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression.2017

    • Author(s)
      Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, Bin BH, Yoshihara T, Ichinoseki-Sekine N, Naito H, Miyatsuka T, Takamiya S, Sasaki T, Inagaki T, Kitamura T, Kajimura S, Watada H, Fujitani Y.
    • Journal Title

      PLoS Genet.

      Volume: 13(8) Issue: 8 Pages: 1-23

    • DOI

      10.1371/journal.pgen.1006950

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09764, KAKENHI-PROJECT-16K09765, KAKENHI-PROJECT-25291002, KAKENHI-PROJECT-17H03631, KAKENHI-PROJECT-17H04011
  • [Journal Article] Hypokalemia and pendrin induction by aldosterone2017

    • Author(s)
      Xu N, Hirohama D, Ishizawa K, Chang WX, Shimosawa T, Fujita T, Uchida S, Shibata S.
    • Journal Title

      Hypertrension

      Volume: 69 Pages: 855-862

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04837
  • [Journal Article] Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3.2016

    • Author(s)
      Ishizawa K, Xu N, Loffing J, Lifton RP, Fujita T, Uchida S, Shibata S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 480 Pages: 745-751

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04837
  • [Journal Article] Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury2016

    • Author(s)
      Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Takeshi Marumo, Atsu Aiba, Takayuki Sakurai, Takayuki Shindo, Toshiro Fujita
    • Journal Title

      Hypertension

      Volume: 67 Issue: 1 Pages: 99-106

    • DOI

      10.1161/hypertensionaha.115.06054

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26860546, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26670426, KAKENHI-PROJECT-26670427, KAKENHI-PROJECT-26293085
  • [Journal Article] Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis.2016

    • Author(s)
      Currie G, Taylor AH, Fujita T, Ohtsu H, Lindhardt M, Rossing P, Boesby L, Edwards NC, Ferro CJ, Townend JN, van den Meiracker AH, Saklayen MG, Oveisi S, Jardine AG, Delles C, Preiss DJ, Mark PB.
    • Journal Title

      BMC Nephrol.

      Volume: 17 Issue: 1 Pages: 127-140

    • DOI

      10.1186/s12882-016-0337-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460332, KAKENHI-PROJECT-16K15494, KAKENHI-PROJECT-15H05788
  • [Journal Article] Diabetes Induces Aberrant DNA Methylation in the Proximal Tubules of the Kidney.2015

    • Author(s)
      Marumo T, Yagi S, Kawarazaki W, Nishimoto M, Ayuzawa N, Watanabe A, Ueda K, Hirahashi J, Hishikawa K, Sakurai H, Shiota K, Fujita T.
    • Journal Title

      J Am Soc Nephrol.

      Volume: 印刷中 Issue: 10 Pages: 2333-2397

    • DOI

      10.1681/asn.2014070665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860669, KAKENHI-PROJECT-15H03001, KAKENHI-PROJECT-25461230, KAKENHI-PROJECT-26670426
  • [Journal Article] Renal mechanisms of salt-sensitive hypertension: contribution of two steroid receptor-associated pathways2015

    • Author(s)
      Nishimoto M, Fujita T
    • Journal Title

      Am J Physiol Renal Physiol.

      Volume: in press Issue: 5 Pages: F377-F387

    • DOI

      10.1152/ajprenal.00477.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Journal Article] Rac1-mediated activation of mineralocorticoid receptor in pressure overload-induced cardiac injury2015

    • Author(s)
      Ayuzawa N, Nagase M, Ueda K, Nishimoto M, Kawarazaki W, Marumo T, Sakurai T, Shindo T, Fujita T
    • Journal Title

      Hypertension

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02538
  • [Journal Article] Mechanism of Salt-Sensitive Hypertension : Focus on Adrenal and Sympathetic Nervous Systems2014

    • Author(s)
      Fujita T
    • Journal Title

      J Am Soc Nephrol

      Volume: 25(6) Pages: 1148-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor2014

    • Author(s)
      Kohei Ueda, Katsunori Fujiki, Katsuhiko Shirahige, Celso E. Gomez-Sanchez, Toshiro Fujita, Masaomi Nangaku, Miki Nagase.
    • Journal Title

      Biochemical and Biophysical Research Commnications

      Volume: 445 Issue: 1 Pages: 132-137

    • DOI

      10.1016/j.bbrc.2014.01.125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J07144, KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410
  • [Journal Article] Local Mineralocorticoid Receptor Activation and the Role of Rac1 in Obesity-Related Diabetic Kidney Disease.2014

    • Author(s)
      Yoshida S, Ishizawa K, Ayuzawa N, Ueda K, Takeuchi M, Kawarazaki W, Fujita T, Nagase M.
    • Journal Title

      Nephron Exp Nephrol

      Volume: in press Issue: 1 Pages: 16-24

    • DOI

      10.1159/000358758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410, KAKENHI-PROJECT-24790835
  • [Journal Article] Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading2014

    • Author(s)
      Yoshida S, Ishizawa K, Ayuzawa N, Ueda K, Takeuchi M, Kawarazaki W, Fujita T, Nagase M.
    • Journal Title

      Clin Exp Nephrol

      Volume: in press Issue: 4 Pages: 593-599

    • DOI

      10.1007/s10157-013-0893-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410
  • [Journal Article] Mechanism of Salt-Sensitive Hypertension: Focus on Adrenal and Sympathetic Nervous Systems2014

    • Author(s)
      Fujita, T
    • Journal Title

      J Am Soc Nephrol

      Volume: in press Issue: 6 Pages: 1148-1155

    • DOI

      10.1681/asn.2013121258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24659410, KAKENHI-PROJECT-26670426
  • [Journal Article] Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease2013

    • Author(s)
      Nagase M, Fujita T
    • Journal Title

      Nat Rev Nephrol

      Volume: 9(2) Pages: 86-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Basichelix-loop-helix transcriptional factor MyoR regulates BMP-7 in acute kidney injury.2013

    • Author(s)
      Kamiura N, Hirahashi J, Matsuzaki Y, Idei M, Takase O, Fujita T, TakatoT, Hishikawa K.
    • Journal Title

      Am J Physiol RenalPhysiol.

      Volume: 304(9) Issue: 9 Pages: 2493-2500

    • DOI

      10.1152/ajprenal.00510.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590878, KAKENHI-PROJECT-23591183, KAKENHI-PROJECT-23591184, KAKENHI-PROJECT-24659789
  • [Journal Article] A useful method of identifying of miRNAs which can down-regulate Zeb-22013

    • Author(s)
      Shigeyoshi Oba, Takayuki Mizutani, Etsu Suzuki, Hiroaki Nishimatsu, Masao Takahashi, Yousuke Ogawa, Kenjiro Kimura, Yasunobu Hirata, and Toshiro Fujita
    • Journal Title

      BMC Res Notes

      Volume: 6 Issue: 1 Pages: 1-8

    • DOI

      10.1186/1756-0500-6-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-24659410
  • [Journal Article] FRET-based sensor analysis reveals caveolae are spatially distinct Ca2+ stores in endothelial cells.2013

    • Author(s)
      Isshiki, M., Nishimoto, M., Mizuno, R., and Fujita, T.
    • Journal Title

      Cell Calcium

      Volume: 54 Issue: 6 Pages: 395-403

    • DOI

      10.1016/j.ceca.2013.09.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24659410
  • [Journal Article] The role of CNS in salt-sensitive hypertension2013

    • Author(s)
      Fujita, M., and Fujita, T
    • Journal Title

      Curr Hypertens Rep

      Volume: 15 Issue: 4 Pages: 390-394

    • DOI

      10.1007/s11906-013-0358-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24591226, KAKENHI-PROJECT-24659410
  • [Journal Article] The role of adrenomedullin in the renal NADPH oxidase and (pro)renin in diabetic mice.2013

    • Author(s)
      Hayashi, M., Tojo, A., Shimosawa, T., and Fujita, T.
    • Journal Title

      J Diabetes Res

      Volume: - Pages: 134395-134395

    • DOI

      10.1155/2013/134395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-23591214, KAKENHI-PROJECT-24659410
  • [Journal Article] The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells2013

    • Author(s)
      Takase O, Yoshikawa M, Idei M, Hirahashi J, Fujita T, Takato T, Isagawa T, Nagae G, Suemori H, Aburatani H, Hishikawa K
    • Journal Title

      PLoS One

      Volume: 8(2) Issue: 2 Pages: e56399-e56399

    • DOI

      10.1371/journal.pone.0056399

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20114007, KAKENHI-PROJECT-22590878, KAKENHI-PROJECT-23591184, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-25860521, KAKENHI-PUBLICLY-23118508
  • [Journal Article] Oxidative stress augments pulmonary hypertension in chronically hypoxic mice overexpressing oxidized LDL receptor.2013

    • Author(s)
      Ogura S, Shimosawa T, Mu SY, Sonobe T, Kawakami-Mori F, Wang H, Uetake y. Yoshida K, Yatomi Y, S hirai M, Fujita T.
    • Journal Title

      Am J Physiol Heart and Circ Physiol

      Volume: 305(2) Issue: 2 Pages: H155-H162

    • DOI

      10.1152/ajpheart.00169.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J10987, KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-23249038, KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-24659410, KAKENHI-PROJECT-24790863
  • [Journal Article] A novel link between Slc22a18 and fat accumulation revealed by a mutation in the spontaneously hypertensive rat.2013

    • Author(s)
      Yamamoto, T., Izumi-Yamamoto, K., Iizuka, Y., Shirota, M., Nagase, M., Fujita, T., and Gotoda, T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 440 Issue: 4 Pages: 521-526

    • DOI

      10.1016/j.bbrc.2013.09.096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410, KAKENHI-PROJECT-24790909
  • [Journal Article] Role of Racl - mineralocorticoid receptor signalling in renal and cardiacdisease.2013

    • Author(s)
      Nagase M, et al.
    • Journal Title

      Nat. Rev. Nephrol.

      Volume: 9 Issue: 2 Pages: 86-98

    • DOI

      10.1038/nrneph.2012.282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410
  • [Journal Article] The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.2013

    • Author(s)
      Takase O, Yoshikawa M, Idei M, Hirahashi J, Fujita T, Takato T, Isagawa T, Nagae G, Suemori H, Aburatani H, Hishikawa K.
    • Journal Title

      PLoS One.

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591183
  • [Journal Article] Aberrant Rac1-mineralocorticoid receptor pathways in salt-sensitive hypertension2013

    • Author(s)
      Kawarazaki, W., and Fujita, T
    • Journal Title

      Clin Exp Pharmacol Physiol

      Volume: 40 Issue: 12 Pages: 929-936

    • DOI

      10.1111/1440-1681.12177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-24659410, KAKENHI-PROJECT-25860669
  • [Journal Article] V2 vasopressin receptor (V2R) mutations in partial nephrogenic diabetes insipidus highlight protean agonism of V2R antagonists2012

    • Author(s)
      Takahashi K, Fujita T, et al.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 2099-2106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Pathophysiology of salt sensitivity hypertension.2012

    • Author(s)
      Ando K, Fujita T
    • Journal Title

      Ann Med

      Volume: 44 Issue: sup1 Pages: S119-S126

    • DOI

      10.3109/07853890.2012.671538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-22590908, KAKENHI-PROJECT-24659410
  • [Journal Article] NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus2012

    • Author(s)
      Kawakami-Mori F, Shimosawa T, Mu S, Wang H, Ogura S, Yatomi Y, Fujita T.
    • Journal Title

      Am J Physiol Endocrinol Metab

      Volume: 302 Issue: 4 Pages: E425-E432

    • DOI

      10.1152/ajpendo.00227.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-23591213, KAKENHI-PROJECT-24659410
  • [Journal Article] Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes : role of small GTPase Rac12012

    • Author(s)
      Nagase M, Ayuzawa N, Kawarazaki W, Ishizawa K, Ueda K, Yoshida S, Fujita T
    • Journal Title

      Hypertension

      Volume: 59(2) Pages: 500-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Reply to: Does a beta(2)-adrenergic receptor-WNK4-Na-Cl co-transporter signal cascade exist in the in vivo kidney?2012

    • Author(s)
      Mu S, Shimosawa T, Fujita T
    • Journal Title

      Nat Med

      Volume: 18 Pages: 1325-1327

    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Sympathoexcitation by brain oxidative stress mediates arterial pressure elevation in salt-induced chronic kidney disease2012

    • Author(s)
      Fujita M, Fujita T, et al.
    • Journal Title

      Hypertension

      Volume: 59 Pages: 105-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus2012

    • Author(s)
      Kawakami-Mori F, Fujita T, et al.
    • Journal Title

      Am J Physiol Endocrinol Metab

      Volume: 302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation2012

    • Author(s)
      Kawarazaki W, Fujita T, et al.
    • Journal Title

      J Am Soc Nephrol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptors in the pathophysiology of chronic kidney diseases and the metabolic syndrome2012

    • Author(s)
      Shibata S, Fujita T
    • Journal Title

      Mol Cell Endocrinol

      Volume: 350(2)

    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes : role of small GTPase Rac12012

    • Author(s)
      Nagase M, Fujita T, et al.
    • Journal Title

      Hypertension

      Volume: 59 Pages: 500-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] NADPH oxidase-mediated Rac1 GTP activity is necessary for non-genomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus2012

    • Author(s)
      Kawakami-Mori F, Shimosawa T, Mu S, Wang H, Ogura S, Yatomi Y, Fujita T
    • Journal Title

      Am J Physiol Endoc Metab

      Volume: 302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Sympathoexcitation by brain oxidative stress mediates arterial pressure elevation in salt-induced chronic kidney disease2012

    • Author(s)
      Fujita M, Ando K, Kawarazaki H, Kawarasaki C, Muraoka K, Ohtsu H, Shimizu H, Fujita T
    • Journal Title

      Hypertension

      Volume: 59(1) Pages: 105-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus2012

    • Author(s)
      Kawakami-Mori F, Fujita T, et al.
    • Journal Title

      Am J Physiol Endocrinol Metab

      Volume: 302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Sympathoexcitation by brain oxidative stress mediates arterial pressure elevation in salt-induced chronic kidney disease2012

    • Author(s)
      Fujita M, Fujita T, et al.
    • Journal Title

      Hypertension

      Volume: 59 Pages: 105-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation2012

    • Author(s)
      Kawarazaki W, Nagase M, Yoshida S, Takeuchi M, Ihizawa N, Ueda K, Fujita T
    • Journal Title

      J Am Soc Nephrol

      Volume: 23 Issue: 6 Pages: 997-1007

    • DOI

      10.1681/asn.2011070734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-21390261, KAKENHI-PROJECT-24390214, KAKENHI-PROJECT-24659410
  • [Journal Article] Mineralocorticoid receptors in the pathophysiology of chronic kidney diseases and the metabolic syndrome2012

    • Author(s)
      Shibata S, Fujita T
    • Journal Title

      Mol Cell Endocrinol

      Volume: 350 Pages: 273-280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac12012

    • Author(s)
      Nagase M, Ayuzawa N, Kawarazaki W, Ishizawa K, Ueda K, Yoshida S, Fujita T.
    • Journal Title

      Hypertension

      Volume: 59 Issue: 2 Pages: 500-6

    • DOI

      10.1161/hypertensionaha.111.185520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-21390261, KAKENHI-PROJECT-24659410
  • [Journal Article] V2 vasopressin receptor (V2R) mutations in partial nephrogenic diabetes insipidus highlight protean agonism of V2R antagonists2012

    • Author(s)
      Takahashi K, Fujita T, et al.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 2099-2106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Aberrantly glycosylated IgA1 as a factor in the pathogenesis of IgA nephropathy2012

    • Author(s)
      Tanaka M, Fujita T, et al.
    • Journal Title

      Clin Dev Immunol

      Volume: (in press) Issue: 2 Pages: 198-199

    • DOI

      10.1111/j.1744-9987.2011.01041.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation2012

    • Author(s)
      Kawarazaki W, Nagase M, Yoshida S, Takeuchi M, Ishizawa K, Ayuzawa N, Ueda K, Fujita T
    • Journal Title

      Am Soc Nephrol

      Volume: 23(6) Pages: 997-1007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] New short interfering RNA-based therapies for glomerulonephritis. Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+-HCO3-cotransporter NBCe1A2011

    • Author(s)
      Yamazaki O, Fujita T, et al.
    • Journal Title

      Pflugers Arch.

      Volume: 461 Pages: 249-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Silver-enhanced immunogold scanning electron microscopy using vibratome sections of rat kidneys : detection of albumin filtration and reabsorption2011

    • Author(s)
      Kinugasa S, Fujita T, et al.
    • Journal Title

      Med Mol Morphol

      Volume: 43 Pages: 218-225

    • NAID

      10027752382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] New short interfering RNA-based therapies for glomerulonephritis2011

    • Author(s)
      Shimizu H, Fujita T
    • Journal Title

      Nat RevNephrol

      Volume: 7 Pages: 407-415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody-associated glomerul onephritis2011

    • Author(s)
      Hanamura K, Fujita T, et al.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 649-658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Aberrantly glycosylated IgAl as a factor in the pathogenesis of IgA nephropathy.2011

    • Author(s)
      Tanaka M, Fujita T, et al.
    • Journal Title

      Clin Dev Immunol

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension.2011

    • Author(s)
      Shibata S, Fujita T.
    • Journal Title

      Curr Hypertens Rep

      Volume: 13 Pages: 109-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Eicosapentaenoic acidregulates IκBα and preventstubulointerstitial injury in kidney.2011

    • Author(s)
      Takase O, Hishikawa K, Kamiura N, Nakakuki M, Kawano H, MizuguchiK, Fujita T.
    • Journal Title

      Eur J Pharmacol.

      Volume: 669(1-3) Issue: 1-3 Pages: 128-35

    • DOI

      10.1016/j.ejphar.2011.07.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Journal Article] The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension2011

    • Author(s)
      Shibata S, Fujita T
    • Journal Title

      Curr Hypertens Rep

      Volume: 13 Pages: 109-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] New short interfering RNA-based therapies for glomerulonephritis. Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+-HCO3- cotransporter NBCe1A2011

    • Author(s)
      Yamazaki O, Fujita T, et al.
    • Journal Title

      Pflugers Arch.

      Volume: 461 Pages: 249-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Functional characterization of nonsynonymous single nucleotide polymor phisms in the electrogenic Na+-HCO3- cotransporter NBCe1A2011

    • Author(s)
      Yamazaki O, Fujita T, et al.
    • Journal Title

      Pflugers Arch

      Volume: 461 Pages: 249-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension2011

    • Author(s)
      Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T
    • Journal Title

      Nat Med

      Volume: 17 Pages: 573-580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibrobl asts against oxidative stress under ischemic conditions.2011

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 128-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Serum biological antioxidant potential predicts the prognosis of hemodialysis patients.2011

    • Author(s)
      Ishii T, Fujita T, et al.
    • Journal Title

      Nephron Clin Pract

      Volume: 117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Role of leukotriene B4 in accelerated hyperlipidaemic renal injury.2011

    • Author(s)
      Doi K, Fujita T, et al.
    • Journal Title

      Nephrology (Carlton)

      Volume: 16 Pages: 304-309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions2011

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 17 Pages: 128-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Role of leukotriene B4 in accelerated hyperhpidaemic renal injury.2011

    • Author(s)
      Doi K, Fujita T, et al
    • Journal Title

      Nephrology(Carlton)

      Volume: 16 Pages: 304-309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Anti-FGF23 neutralizing antibodies ameliorate muscle weakness and decreased spontaneous movement of Hyp mice.2011

    • Author(s)
      Aono Y, Fujita T, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 26 Pages: 803-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.2011

    • Author(s)
      Mu SY, Fujita T, et al.
    • Journal Title

      Nat Med

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease2011

    • Author(s)
      Hasegawa H, Fujita T, et al.
    • Journal Title

      Kidney Int.

      Volume: 78 Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Endocrinological aspects of proteinuria and podocytopathy in diabetes : role of the aldosterone/mineralocorticoid receptor system.2011

    • Author(s)
      Nagase M, Fujita T.
    • Journal Title

      Curr Diabetes Rev

      Volume: 7 Pages: 8-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] New short interfering RNA-based therapies for glomerulonephritis2011

    • Author(s)
      Shimizu H, Fujita T
    • Journal Title

      Nat Rev Nephrol

      Volume: 7 Issue: 7 Pages: 407-415

    • DOI

      10.1038/nrneph.2011.61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-21390261
  • [Journal Article] Endocrinological aspects of proteinuria and Podocytopathy in diabetes : role of the aldosterone/mineralocorticoid receptor system2011

    • Author(s)
      Nagase M, Fujita T.
    • Journal Title

      Curr Diabetes Rev

      Volume: 7(1) Pages: 8-16

    • URL

      http://www.benthamdirect.org/pages/content.php?CDR/2011/00000007/00000001/D0003D.SGM

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] GADD45ss Determines Chemoresistance and invasive Growth of Side Population Cells of Human Embryonic Carcinoma2011

    • Author(s)
      Inowa T, Fujita T, et al.
    • Journal Title

      Stem Cells Int

      Volume: 14 Pages: 782967-782967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease2011

    • Author(s)
      Hasegawa H, Fujita T, et al.
    • Journal Title

      Kidney Int.

      Volume: 78 Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Serum biological antioxidant potential predicts the prognosis of hemodialysis patients.2011

    • Author(s)
      Ishii T, Fujita T, et al.
    • Journal Title

      Nephron Clin Pract

      Volume: 117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Common variation in GPC5 is associated with acquired nephrotic syndrome.2011

    • Author(s)
      Okamoto K, Fujita T, et al.
    • Journal Title

      Nat Genet

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2011

    • Author(s)
      Jutabha P, Fujita T, et al.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 35123-35132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] The relative role of, fibroblast growth factor 23 and parathyroid hormone in predicting future hypophosphatemia and hypercalcemia after living donor kidney transplantation : a 1-year prospective observational study.2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway2011

    • Author(s)
      Shibata S, Mu S, Kawarazaki H, Muraoka K, Ishizawa K, Yoshida S, Kawarazaki W, Takeuchi M, Ayusawa N, Miyoshi J, Takai Y, Ishikawa A, Shimosawa T, Ando K, Nagase M, Fujita T
    • Journal Title

      J Clin Invest

      Volume: 121 Pages: 3233-3243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Neutrophil elastase contribute to acute lung injury induced by bilateral nephrectomy2011

    • Author(s)
      Ishii T, Fujita T, et al.
    • Journal Title

      Am J Pathol.

      Volume: 177 Pages: 1665-1673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARy-dependent non-genomic signaling.2011

    • Author(s)
      Endo Y, Fujita T, et al.
    • Journal Title

      Cell Metab

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptor activation : a major contributor to salt-induced renal injury and hypertension in young rats2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in t2011

    • Author(s)
      Yamada H, Fujita T, et al.
    • Journal Title

      Channels (Austin)

      Volume: 5 Pages: 106-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Endocrinological aspects of proteinuria and podocytopathy in diabetes : role of the aldosterone/mineralocorticoid receptor system2011

    • Author(s)
      Nagase M, Fujita T
    • Journal Title

      Curr Diabetes Rev

      Volume: 7 Pages: 8-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Defective membrane expression of the Na(+)-HCO(3)(-)cotransporter NB Ce1 is associated with familial migraine2011

    • Author(s)
      Suzuki M, Fujita T, et al.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 107 Pages: 15963-15968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Common variation in GPC5 is associated with acquired nephrotic syndrome2011

    • Author(s)
      Okamoto K, Tokunaga K, Doi K, Fujita T, Suzuki H, Katoh T, Watanabe T, Nishida N, Mabuchi A, Takahashi A, Kubo M, Maeda S, Nakamura Y, Noiri E
    • Journal Title

      Nat Genet

      Volume: 43(5) Pages: 459-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptor activation : a major contributor to salt-induced renal injury and hypertension in young rats.2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] The relative role of fibroblast growth factor 23 and parathyroid hormone in predicting future hypophosphatemia and hypercalcemia after living donor kidney transplantation : a 1-year prospective observational study.2011

    • Author(s)
      Kaawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Eicosapentaenoic acid regulates IkBa and prevents tubulointestitial injury in kidney2011

    • Author(s)
      Takase O, Hishikawa K, Kamiura M, Kawano H, Mizuguchi K, Fujita T
    • Journal Title

      Eur J Pharmacol

      Volume: 669 Pages: 128-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591183
  • [Journal Article] The relative role of fibroblast growth factor 23 and parathyroid hormone in predicting future hypophosphatemia and hypercalcemia after living donor kidney transplantation : a 1-year prospective observational study2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 26 Pages: 2691-2695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Functional characterization of nonsynonymous single nucleotide polymor phisms in the electrogenic Na+-HCO3-cotransporter NBCe1A.2011

    • Author(s)
      Yamazaki 0, Fujita T, et al.
    • Journal Title

      Pflugers Arch

      Volume: 461 Pages: 249-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosis.2011

    • Author(s)
      Lo YF, Fujita.T, et al.
    • Journal Title

      Kidney Int

      Volume: 79 Pages: 730-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions.2011

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 128-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosis.2011

    • Author(s)
      Lo YF, Fujita T, et al.
    • Journal Title

      Kidney Int

      Volume: 79 Pages: 730-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Endocrinological Aspects of Proteinuria and Podocytopathy in Diabetes : Role of the Aldosterone/Mineralocorticoid Receptor System2011

    • Author(s)
      Miki Nagase, Thshiro Fujita
    • Journal Title

      Current Diabetes Reviews

      Volume: 7 Pages: 8-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats.2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na(+)-HCO3(-) cotransporter NBC e1 expressed in Xenopus oocytes2011

    • Author(s)
      Yamada H, Fujita T, et al.
    • Journal Title

      Channels

      Volume: 5 Pages: 106-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] GADD45SS Determines Chemoresistance and invasive Growth of Side Population Cells of Human Embryonic Carcinoma2011

    • Author(s)
      Inowa T, Fujita T, et al.
    • Journal Title

      Stem Cells Int

      Volume: 14 Pages: 782967-782967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions2011

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 17 Pages: 128-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPAR_Y-dependent non-genomic signaling2011

    • Author(s)
      Endo Y, Fujita T, et al.
    • Journal Title

      Cell Metab

      Volume: 13 Pages: 550-561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Epigenetic modulation of the renal f-adrenergic-WNK4 pathway in salt-sensitive hypertension.2011

    • Author(s)
      Mu SY, Fujita T, et al.
    • Journal Title

      Nat Med

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2011

    • Author(s)
      Jutabha P, Fujita T, et al.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 35123-35132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Epigenetic modulation of the renal ss-adrenergic-WNK4 pathway in salt-sensitive hypertension2011

    • Author(s)
      Mu SY, Fujita T, et al.
    • Journal Title

      Nat Med

      Volume: 17 Pages: 573-580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Neutrophil elastase contribute to acute lung injury induced by bilateral nephrectomy2011

    • Author(s)
      Ishii T, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 1665-1673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] miR-200b precursor can ameliorate renal tubulointerstitial fibrosis2011

    • Author(s)
      Oba S, Fujita T, et al.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPAR_Y-dependent non-genomic signaling2011

    • Author(s)
      Endo Y, Fujita T, et al.
    • Journal Title

      Cell Metab

      Volume: 13 Pages: 550-561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Thiazolidinedioues enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent non-genomic signaling.2011

    • Author(s)
      Endo Y, Fujita T, et al.
    • Journal Title

      Cell Metab

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na(+)-HCO3(-)cotransporter NBCel expressed in Xenopus oocytes2011

    • Author(s)
      Yamada H, Fujita T, et al.
    • Journal Title

      Channels

      Volume: 5 Pages: 106-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Epigenetic modulation of the renal ss-adrenergic-WNK4 pathway in salt-sensitive hypertension2011

    • Author(s)
      Mu SY, Fujita T, et al.
    • Journal Title

      Nat Med

      Volume: 17 Pages: 573-580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Aberrantly glycosylated IgA1 as a factor in the pathogenesis of IgA nephropathy.2011

    • Author(s)
      Tanaka M, Fujita T, et al.
    • Journal Title

      Clin Dev Immunol

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension2011

    • Author(s)
      Shibata S, Fujita T
    • Journal Title

      Curr Hypertens Rep

      Volume: 13 Pages: 109-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Anti-FGF23 neutralizing antibodies ameliorate muscle weakness and decreased spontaneous movement of Hyp mice2011

    • Author(s)
      Aono Y, Fujita T, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 26 Issue: 4 Pages: 803-810

    • DOI

      10.1002/jbmr.275

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-21390261, KAKENHI-PROJECT-21390284
  • [Journal Article] Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody-associated glomerul onephritis.2011

    • Author(s)
      Hanamura K, Fujita T, et al.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 649-658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Mineralocorticoid receptor activation : a major contributor to salt-induced renal injury and hypertension in young rats2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase2011

    • Author(s)
      Kinugasa S, Fujita T, et al.
    • Journal Title

      Kidney Int.

      Volume: 80 Issue: 12 Pages: 1328-1338

    • DOI

      10.1038/ki.2011.282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012, KAKENHI-PROJECT-21390261, KAKENHI-PROJECT-23591214
  • [Journal Article] Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis2011

    • Author(s)
      Hanamura K, Fujita T, et al.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 649-658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Renal preservation effect of ubiquinol, the reduced form of coenzyme Q1O2011

    • Author(s)
      Isbikawa A, Fujita T, et al.
    • Journal Title

      Clin Exp Nephrol

      Volume: 15 Pages: 30-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] miR-200b precursor can ameliorate renal tubulointerstitial fibrosis2011

    • Author(s)
      Oba S, Fujita T, et al.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na (+) -HCO 3 (-) cotransporter NBCel expressed in Xenopus oocytes.2011

    • Author(s)
      Yamada H, Fujita T, et al.
    • Journal Title

      Channels (Austin)

      Volume: 5 Pages: 106-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Anti-FGF23 neutralizing antibodies ameliorate muscle weakness and decreased spontaneous movement of Hyp mice.2011

    • Author(s)
      Aono Y, Fujita T, et al.
    • Journal Title

      J Bone Miner Res

      Volume: 26 Pages: 803-810

    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Glypican 5 predisposes podocytes to nephrotic proteinuria2011

    • Author(s)
      Okamoto K, Fujita T, et al.
    • Journal Title

      Nat Genet

      Volume: 43 Pages: 459-463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine2011

    • Author(s)
      Suzuki M, Fujita T, et al.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 15963-15968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Glypican 5 predisposes podocytes to nephrotic proteinuria2011

    • Author(s)
      Okamoto K, Fujita T, et al.
    • Journal Title

      Nat Genet

      Volume: 43 Pages: 459-463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling2011

    • Author(s)
      Endo Y, Suzuki M, Yamada H, Horita S, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
    • Journal Title

      Cell Metab

      Volume: 13(5) Pages: 550-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody-associated glomerul onephritis.2011

    • Author(s)
      Hanamura K, Fujita T, et al.
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 649-658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Common variation in GPC5 is associated with acquired nephrotic syndrone.2011

    • Author(s)
      Okamoto K, Fujita T, et al.
    • Journal Title

      Nat Genet

      Volume: (掲載確定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] The relative role of fibroblast growth factor 23 and parathyroid hormone in predicting future hypophosphatemia and hypercalcemia after living donor kidney transplantation : a 1-year prospective observational study2011

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 26 Pages: 2691-2695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Silver-enhanced immunogold scanning electron microscopy using vibratome sections of rat kidneys : detection of albumin filtration and reabsorption2011

    • Author(s)
      Kinugasa S, Fujita T, et al.
    • Journal Title

      Med Mol Morphol

      Volume: 43 Pages: 218-225

    • NAID

      10027752382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.2010

    • Author(s)
      Kawakami T, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Renal preservation effect of ubiquinol, the reduced form of coenzyme Q102010

    • Author(s)
      Ishikawa A, Fujita T, et al.
    • Journal Title

      Clin EXp Nephrol

      Volume: 15 Pages: 30-33

    • NAID

      10029004333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats.2010

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 2879-2889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy.2010

    • Author(s)
      Ishii T, Fujita T, et al.
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 1665-1673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] siRNA-based therapy for glomerulonephritis2010

    • Author(s)
      Shimizu H, Hori Y, Kaname S, Yamada K, Nishiyama N, Matsumoto S, Miyata K, Oba M, Yamada A, Kataoka K, Fujita T
    • Journal Title

      J Am Soc Nephrol

      Volume: 21(4) Pages: 622-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome2010

    • Author(s)
      Fujita T.
    • Journal Title

      Hypertension

      Volume: 55(4) Issue: 4 Pages: 813-8

    • DOI

      10.1161/hypertensionaha.109.149062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.2010

    • Author(s)
      Palm F, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Long-term clinical course of IgG4-related systemic disease accompanied by hypophysitis.2010

    • Author(s)
      Hori M, Fujita T, et al.
    • Journal Title

      Endocr J

      Volume: 57 Pages: 485-492

    • NAID

      10029585054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Very low but stable glomerular filtration rate after living kidney donation : is the concept of "chronic kidney disease" applicable to kidney donors2010

    • Author(s)
      Kido R, Fujita T, et al
    • Journal Title

      Clin Exp Nephrol

      Volume: 14 Pages: 356-362

    • NAID

      10027706776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] miR-200b precursor can ameliorate renal tubulointerstitial fibrosis.2010

    • Author(s)
      Oba S, Fujita T, et al.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated- with acute kidney injury.2010

    • Author(s)
      Doi K, Fujita T, et al.
    • Journal Title

      Crit Care Med

      Volume: 38 Pages: 2037-2042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect Study Investigators.Rationale and design of the Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial : a double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric effects of an aldosterone blocker in hypertensive patients with albuminuria.2010

    • Author(s)
      Ando K, Fujita T, et al.
    • Journal Title

      Hypertens Res

      Volume: 33 Pages: 616-621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Long-term clinical course of IgG4-related systemic disease accompanied by hypophysitis.2010

    • Author(s)
      Hori M, Fujita T, et al.
    • Journal Title

      Endocr J

      Volume: 57 Pages: 485-492

    • NAID

      10029585054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease.2010

    • Author(s)
      Hasegawa H, Fujita T, et al.
    • Journal Title

      Kidney Int

      Volume: 78 Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] miR-200b precursor can ameliorate renal tubulointerstitial fibrosis.2010

    • Author(s)
      Oba S, Fujita T, et al.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.2010

    • Author(s)
      Fujita T
    • Journal Title

      Hypertension

      Volume: 53 Pages: 813-818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Virus removal and eradication by modified double filtration plasmapheresis decreases factor XIII levels.2010

    • Author(s)
      Hanafusa N, Fujita T, et al.
    • Journal Title

      Ther Apher Dial

      Volume: 14 Pages: 287-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] siRNA-based therapy ameliorates glomerulonephritis.2010

    • Author(s)
      Shimizu H, Fujita T, et al.
    • Journal Title

      J Am Soc Nephrol 21

      Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.2010

    • Author(s)
      Kawakami T, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] siRNA-based therapy for glomerulonephritis.2010

    • Author(s)
      Shimizu H, Fujita T, et al.
    • Journal Title

      J Am See Nephrol

      Volume: 21 Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] siRNA-based therapy for glomerulonephritis.2010

    • Author(s)
      Shimizu H, Fujita T, et al.
    • Journal Title

      J Am Soc Nephrol

      Volume: 21 Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Resolution of Henoch-Schonlein purpura nephritis after acquired IgA deficiency.2010

    • Author(s)
      Tanaka M, Fujita T, at al.
    • Journal Title

      Pediatr Nephrol

      Volume: 25 Pages: 2356-2358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Localization and mechanism of nephrocalcinosis in pseudo-Bartter's synd rome..2010

    • Author(s)
      Tojo A, Fujita T, et al.
    • Journal Title

      Kidney Int

      Volume: 77 Pages: 831-831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated with acute kidney injury.2010

    • Author(s)
      Doi K, Fujita T, at al.
    • Journal Title

      Crit Care Med

      Volume: 38 Pages: 2037-2042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Endocrinological Aspects of Proteinuria and Podocytopathy in Diabetes : Role of the Aldosterone/Mineralocorticoid Receptor System2010

    • Author(s)
      Miki Nagase, Toshiro Fujita
    • Journal Title

      Current Diabetes Reviews (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Silver-enhanced immunogold scanning electron microscopy using vibratome sections of rat kidneys : detection of albumin filtration and reabsorption.2010

    • Author(s)
      Kinugasa S, Fujita T, et al.
    • Journal Title

      Med Mot Morphol

      Volume: 43 Pages: 218-225

    • NAID

      10027752382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] The role of glyoxalase system in renal hypoxia.2010

    • Author(s)
      Inagi R, Fujita T, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 49-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Human sodium phosphate transporter 4.(hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.2010

    • Author(s)
      Jutabha P, Fujita T, et al.
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 35123-35132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Trichostatin, a prevents TGF-betal-induced apoptosis by inhibiting ERK activation in human renal tubular epithelial cells.2010

    • Author(s)
      Yoshikawa M, Fujita T, et al.
    • Journal Title

      Eur J Pharmacol

      Volume: 642 Pages: 28-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Virus removal and eradication by modified double filtration plasmapher esis decreases factor XIII levels.2010

    • Author(s)
      Hanafusa N, Fujita T, et al.
    • Journal Title

      Ther Apher Dial

      Volume: 14 Pages: 287-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCel is associated with familial migraine.2010

    • Author(s)
      Suzuki M, Fujita T, et al
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 15963-15968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Platelet-derived microparticles are removed by a membrane plasma separator.2010

    • Author(s)
      Hanafusa N, Fujita T, et al.
    • Journal Title

      ASAIO J

      Volume: 56 Pages: 323-3325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.2010

    • Author(s)
      Fujita T
    • Journal Title

      Hypertension

      Volume: 53 Pages: 813-818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Platelet-derived microparticles are removed by a membrane plasma separator.2010

    • Author(s)
      Hanafusa N, Fujita T, et al.
    • Journal Title

      ASATO J

      Volume: 56 Pages: 323-3325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Cytoglobin, a novel globin, plays an antifibrotic role in the kidney.2010

    • Author(s)
      Mimura I, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Silver-enhanced immunogold scanning electron microscopy using vibr atome sections of rat kidneys : detection of albumin filtration and reabsorption.2010

    • Author(s)
      Kinugasa S, Fujita T, et al.
    • Journal Title

      Med Mol Morphol

      Volume: 43 Pages: 218-225

    • NAID

      10027752382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a commonrenal secretory pathway for drugs and urate.2010

    • Author(s)
      Jutabha P, Fujita T, et al.
    • Journal Title

      J Biol Chem

      Volume: 285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Cytoglobin, a novel globin, plays an antifibrotic role in the kidney.2010

    • Author(s)
      Mimura I, Fujita T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Resolution of Henoch-SchOnlein purpura nephritis after acquired IgA def_iciency.2010

    • Author(s)
      Tanaka M, Fujita T, et al.
    • Journal Title

      Pediatr Nephrol

      Volume: 125 Pages: 2355-2358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Very low but stable glomerular filtration rate' after living kidney donation : is the concept of "chronic kidney disease" applicable to kidney donors?2010

    • Author(s)
      Kido R, Fujita T, et al.
    • Journal Title

      Clin Exp Nephrol

      Volume: 14 Pages: 356-362

    • NAID

      10027706776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats.2010

    • Author(s)
      Kawarazaki H, Fujita T, et al.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 2879-2889

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Direct evidence for a causative role of FGF23 in the abnormal renal plosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease.2010

    • Author(s)
      Hasegawa H, Fujita T, at al
    • Journal Title

      Kidney Int

      Volume: 78 Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.2010

    • Author(s)
      Palm F, Fujita T, et al
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect Study Investigators2010

    • Author(s)
      Ando K, Ohtsu H, Arakawa Y, Kubota K, Yamaguchi T, Nagase M, Yamada A, Fujita T.
    • Journal Title

      Hypertens Res

      Volume: 33(6) Issue: 6 Pages: 616-21

    • DOI

      10.1038/hr.2010.46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Persistent glomerular hematuria in living kidney donors confers a risk of progressive kidney disease in donors after heminephrectomy.2010

    • Author(s)
      Kido R, Fujita T, et al
    • Journal Title

      Am J Transplant

      Volume: 10 Pages: 1597-1604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Laboratory and imaging features of kidney involvement in autoimmune pancreatitis : incidence, correlation, and steroid therapy response.2010

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Clin Nephrol

      Volume: 73 Pages: 253-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] The role of glyoxalase system in renal hypoxia.2010

    • Author(s)
      Inagi R, Fujita T, et al.
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 49-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Laboratory and imaging features of kidney involvement in autoimmune pancreatitis : incidence, correlation, and steroid therapy response.2010

    • Author(s)
      Nishi H, Fujita T, et al.
    • Journal Title

      Clin Nephrol

      Volume: 73 Pages: 253-259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCel is associated with familial migraine.2010

    • Author(s)
      Suzuki M, Fujita T, et al.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 107 Pages: 15963-16968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Localization and mechanism of nephrocalcinosis in pseudo-Bartter's syndrome.2010

    • Author(s)
      Tojo A, Fujita T, et al.
    • Journal Title

      Kidney Int

      Volume: 77 Pages: 831-831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Persistent glomerular hematuria in living kidney donors confers arisk of progressive kidney disease in donors after heminephrectomy.2010

    • Author(s)
      Kido R, Fujita T, et al.
    • Journal Title

      Am J Transplant

      Volume: 10 Pages: 1597-1604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptors, saltsensitive hypertension, and metabolic syndrome2010

    • Author(s)
      Fujita T
    • Journal Title

      Hypertension

      Volume: 55(4) Pages: 813-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy.2010

    • Author(s)
      Ishii T, Fujita T, at al.
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 1665-1673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Trichostatin, a prevents TGF-betal-induced apoptosis by inhibiting ERK activation in human renal tubular epithelial cells.2010

    • Author(s)
      Yoshikawa M, Fujita T, et al.
    • Journal Title

      Eur J Pharmacol

      Volume: 642 Pages: 28-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Mineralocorticoid receptors, salt-sensitive hypertensions, and metabolic syndrome2010

    • Author(s)
      Fujita T
    • Journal Title

      Hypertension 55

      Pages: 813-818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mac-1(CD11b/CD18)links inflammation and thrombosis after glomerular injury.2009

    • Author(s)
      Hirahashi J, Fujita T, et al.
    • Journal Title

      Circulation 120

      Pages: 1255-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension2009

    • Author(s)
      Nagae A, Fujita M, Kawarazaki H, Matsui H, Ando K, Fujita T
    • Journal Title

      Circulation

      Volume: 119(7) Pages: 978-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Journal Article] Mineralocorticoid receptor activation in obesity hypertension2009

    • Author(s)
      Nagase M, Fujita T.
    • Journal Title

      Hypertens Res

      Volume: 32(8) Issue: 8 Pages: 649-57

    • DOI

      10.1038/hr.2009.86

    • NAID

      10025164535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Mineralocorticoid receptor activation in obesity hypertension2009

    • Author(s)
      Miki Nagase, Toshiro Fujita
    • Journal Title

      Hypertension Research 32

      Pages: 649-657

    • NAID

      10025164535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390261
  • [Journal Article] Aldosterone enhances ligand-stimulatednitric xoide production in endothelial cells2008

    • Author(s)
      Mutoh A, Isshiki M, Fujita T.
    • Journal Title

      Hypertens Res 31

      Pages: 1811-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Journal Article] Isolation and potential existence of side population cells in adult human kidney2008

    • Author(s)
      Inowa T, Hishikawa K, Takeuchi T, Kitamura T, Fujita T.
    • Journal Title

      Int J Urol 15(3)

      Pages: 272-274

    • NAID

      10021277275

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Protective effect of dietary potassium against the vascular njury in salt-sensitive hypertension.2008

    • Author(s)
      Kido M, Ando K, Onozato ML, Tojo A, Yoshikawa M, Ogita T, Fujita T
    • Journal Title

      Hypertension 51

      Pages: 225-231

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Isolation and potential existence of side population cells in adult human kidney.2008

    • Author(s)
      Inowa T, Hishikawa K, Takeuchi T, Kitamura T, Fujita T
    • Journal Title

      Int J. Urol 15(3)

      Pages: 272-4

    • NAID

      10021277275

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Aldosterone enhances lig and-stimulated Nitric Oxide Production in Endothelial cells.2008

    • Author(s)
      Mutoh A.,Isshiki M., Fujita T.
    • Journal Title

      Hypertens Res 31

      Pages: 1811-1820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Journal Article] Protective effect of dietary potassium against the vascular injury in salt-sensitive hypertension2008

    • Author(s)
      Kido M, Ando K, Onozato ML, Tojo A, Yoshikawa M, Ogita T, Fujita T.
    • Journal Title

      Hypertension 51

      Pages: 225-231

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Adrenomedullin Inhibits Angiotensin II-Induced Oxidative Stress Via Csk-Mediated Inhibition of Src Activity.2007

    • Author(s)
      Liu J, Shimosawa T, Matsui H, Meng F, Supowit SC, DiPette DJ, Ando K, Fujita T
    • Journal Title

      Am J Physiol Heart Circ Physiol 292

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Insulin resistance and salt-sensitive hypertension in metabolic syndrome2007

    • Author(s)
      Fujita T
    • Journal Title

      Nephrol Dial Transplant 22

      Pages: 3102-3107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Podocyte as the target for aldosterone : roles of oxidative stress and Sgkl.2007

    • Author(s)
      Shibata S, Nagase M, Yoshida S, Kawachi H, Fujita T
    • Journal Title

      Hypertension 49

      Pages: 355-364

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Podocyte as the target for aldosterone:roles of oxidative stress and Sgkl2007

    • Author(s)
      Shibata S, Nagase M, Yoshida S, Kawachi H, Fujita T
    • Journal Title

      Hypertension 49

      Pages: 355-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in salt sensitive bypertension.2007

    • Author(s)
      Fijuta M, Ando K, Nagae A, Fujita T
    • Journal Title

      Hypertension 50

      Pages: 360-367

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxicalactivation of the mineralocorticoid receptor:role of oxidative stress2007

    • Author(s)
      Nagase M, Matsui H, Shibata S, Gotoda T, Fujita T
    • Journal Title

      Hypertension 50

      Pages: 877-883

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Adrenomedullin inhibits angiotensin II-induced oxidative stress via Csk-mediated inhibition of Src activity2007

    • Author(s)
      Liu J, Shimosawa T, Matsui H, Meng F, Supowit SC, Dipette DJ, Ando K, Fujita T.
    • Journal Title

      Am J Physiol Heart Circ Physiol 292

      Pages: 1714-1721

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction.2007

    • Author(s)
      Marumo T, Hishikawa K, Matsuzaki Y, Imai N, Takase O, Shimosawa T, Okano H, Fujita T
    • Journal Title

      Eur J. Pharmacol 573

      Pages: 216-20

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury2007

    • Author(s)
      Imai N, Hishikawa K, Marumo T, Hirahashi J, Inowa T, Matsuzaki Y, Okano H, Kitamura T, Salant D, Fujita T.
    • Journal Title

      Stem Cells 25

      Pages: 2469-2475

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-betal in human renal epithelial cells2007

    • Author(s)
      Yoshikawa M, Hishikawa K, Marumo T, Fujita T.
    • Journal Title

      J Am Soc Nephrol 18

      Pages: 58-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-betal in human renal epithelial cells.2007

    • Author(s)
      Yoshikawa M, Hishikawa K, Marumo T, Fujita T
    • Journal Title

      J Am Soc Nephrol 18

      Pages: 58-65

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Angiotensin II type 1 receptor blockade prevents decrease in adult stem-like cells in kidney after ureteral obstruction2007

    • Author(s)
      Marumo T, Hishikawa K, Matsuzaki Y, Imai N, Takase O, Shimosawa T, Okano H, Fujita T.
    • Journal Title

      Eur J Pharmacol 573

      Pages: 216-220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Adrenomedullin inhibits.angiotensin II-induced oxidative stress via Csk-mediated inhibition of Src activity.2007

    • Author(s)
      Liu J, Shimosawa T, Matsui H, Meng F, SupowitSC, Dipette DJ, Ando K, Fujita T
    • Journal Title

      Am J. Physiol Heart Circ Physiol 292

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in salt sensitive hypertension2007

    • Author(s)
      Fijuta M, Ando K, Nagae A, Fujita T
    • Journal Title

      Hypertension 50

      Pages: 360-367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-betal in human renal epithelial cells.2007

    • Author(s)
      Yoshikawa M, Hishikawa K, Marumo T, Fujita T
    • Journal Title

      J. Am Soc Nephrol 18

      Pages: 58-65

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury.2007

    • Author(s)
      Imai N, Hishikawa K, Marumo T, Hirahashi J, Inowa T, Matsuzaki Y, Okano H, Kitamura T, SalantD, Fujita T
    • Journal Title

      Stem Cells 25

      Pages: 2469-75

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in salt sensitive hypertension2007

    • Author(s)
      Fijuta M, Ando K, Nagae A, Fujita T.
    • Journal Title

      Hypertension 50

      Pages: 360-367

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Adrenomedullin inhibits insulin exocytosis via pertussis toxin-sensitive G-protein-coupled mechanism.2006

    • Author(s)
      Sekine N, Takano K, Kimata-Hayashi N, Kadowaki T, Fujita T
    • Journal Title

      Am J Physiol 291

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Klotho converts canonical FGF receptor into a specific receptor for FGF23.2006

    • Author(s)
      Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, Yamashita T
    • Journal Title

      Nature 444

      Pages: 770-774

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Protective Effect of Potassium Against the Hypertensive Cardiac Dysfunction.2006

    • Author(s)
      Matsui H, Shimosawa T, Uetake Y, Wang H, Ogura S, Kaneko T, Liu J, Ando K, Fujita T
    • Journal Title

      Hypertension 48

      Pages: 225-231

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Fluvastatin ameliorates podocyte injury in proteinuric rats via modulation of excessive Rho signaling.2006

    • Author(s)
      Shibata S, Nagase M, Fujita T
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 754-764

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice.2006

    • Author(s)
      Yamamoto K, Sokabe T, Matsumoto T, Yoshimura K, Shibata M, Ohura N, Fukuda T, Sato T, Sekine K, Kato S, Isshiki M, Fujita T, Kobayashi M, Kawamura K, Masuda H, Kamiya A, Ando J.
    • Journal Title

      Nature Med 12

      Pages: 133-7

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Aldosterone impairs bone marrow-derived progenitor cell formation.2006

    • Author(s)
      Marumo T, Uchimura H, Hayashi M, Hishikawa K, Fujita T
    • Journal Title

      Hypertension 48

      Pages: 490-6

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Stem cells and kidney disease2006

    • Author(s)
      Hishikawa K, Fujita T.
    • Journal Title

      Hypertens Res 29

      Pages: 745-749

    • NAID

      10018561054

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Aldosterone impairs bone marrow-derived progenitor cell formation2006

    • Author(s)
      Marumo T, Uchimura H, Hayashi M, Hishikawa K, Fujita T.
    • Journal Title

      Hypertension 48

      Pages: 490-496

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Podocyte injury underlies the glomerulopahy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker.2006

    • Author(s)
      Nagase M, Shibata S, Yoshida S, Nagase T, Gotoda T, Fujita T
    • Journal Title

      Hypertension 47

      Pages: 1084-93

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome : possible contribution of fat-derived factors.2006

    • Author(s)
      Nagase M, Yoshida S, Shibata S, Nagase T, Gotoda T, Ando K, Fujita T
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 3438-3446

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Stem cells and kidney, disease.2006

    • Author(s)
      Hishikawa K, Fujita T
    • Journal Title

      Hypertens Res 29

      Pages: 745-749

    • NAID

      10018561054

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Musculin/Myor is expressed in kidney side population cells and regulate their function.2005

    • Author(s)
      Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, Nakauchi H, Okano H, Fujita T
    • Journal Title

      J. Cell Biol 169

      Pages: 921-928

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] AT1 in molecule page.2005

    • Author(s)
      Noriko Makita, Toshiro Fujita, Taroh Iiri
    • Journal Title

      AfCS in Nature (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] Expression and regulation of adrenomedullin in renal glomerular podocytes2005

    • Author(s)
      Hino M, Nagase M, Kaname S, Shibata S, Nagase T, Oba S, Funaki M, Kobayashi N, Kawachi H, Mundel P, Fujita T.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 178-185

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Renoprotective effect of pravastatin in salt-loaded Dahl salt-sensitive rats2005

    • Author(s)
      Kido M, Ando K, Oba S, Fujita T
    • Journal Title

      Hypetens Res 28

      Pages: 1009-1015

    • NAID

      10017403750

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Musculin/Myor is expressed in kidney side population cells and regulate their function2005

    • Author(s)
      Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, Nakauchi H, Okano H, Fujita T.
    • Journal Title

      J Cell Biol 169

      Pages: 921-928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Renoprotective effect of pravastatin in salt-loaded Dahl salt-sensitive rats2005

    • Author(s)
      Kido M, Ando K, Oba S, Fujita T.
    • Journal Title

      Hypetens Res 28

      Pages: 1009-1015

    • NAID

      10017403750

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Expression and regulation of adrenomedullin in renal glomerular podocytes.2005

    • Author(s)
      Hino M, Nagase M, Kaname S, Shibata S, Nagase T, Oba S, Funaki M, Kobayashi N, Kawachi H, Mundel P, Fujita T
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 178-185

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Roles of CTPL/Sfxn3 and Sfxn family members in pancreatic islet.2005

    • Author(s)
      H Mashima, Y Yoshikumi, N Ueda, H Ohno, J Suzuki, S Tanaka, M Hayashi, N Sekine, H Ohnishi, H Yasuda, T Iiri, M Omata, T Fujita, I Kojima
    • Journal Title

      J.Cell.Biochem. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] Sympatho-inhibitory action of endogenous adrenomedullin through inhibition of oxidative stress in the brain2005

    • Author(s)
      Fujita M, Kuwaki T, Ando K, Fujita T
    • Journal Title

      Hypertension 45

      Pages: 1009-1015

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Intrarenal Injection of Bone Marrow-Derived Angiogenic Cells Reduces Endothelial Injury and Mesangial Cell Activation in Experimental Glomerulonephritis2005

    • Author(s)
      Uchimura H, Marumo T, Takase O, Kawachi H, Shimizu F, Hayashi M, Saruta T, Hishikawa K, Fujita T
    • Journal Title

      J. Am Soc Nephrol 16

      Pages: 997-1004

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Sympatho-inhibitory action of endogenous adrenomedullin through inhibition of oxidative stress in the brain2005

    • Author(s)
      Fujita M, Kuwaki T, Ando K, Fujita T.
    • Journal Title

      Hypertension 45

      Pages: 1165-1172

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Fluvastatin Ameliorates Podocyte Injury in Proteinuric Rats via Modulation of Excessive Rho Signaling2005

    • Author(s)
      Shibata S, Nagase M, Fujita T
    • Journal Title

      J Am Soc Nephrol 17

      Pages: 754-764

    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Intrarenal Injection of Bone Marrow-Derived Angiogenic Cells Reduces Endothelial Injury and Mesangial Cell Activation in Experimental Glomerulonephritis2005

    • Author(s)
      Uchimura H, Marumo T, Takase O, Kawachi H, Shimizu F, Hayashi M, Saruta T, Hishikawa K, Fujita T.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 997-1004

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Sympatho-inhibitory action of endogenous adrenomedullin through inhibition of oxidative stress in the brain.2005

    • Author(s)
      Fujita M, Kuwaki T, Ando K, Fujita T
    • Journal Title

      Hypertension 45

      Pages: 1165-1172

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Renoprotective effect of pravastatin in salt-loaded Dahl salt-sensitive rats.2005

    • Author(s)
      Kido M, Ando K, Oba S, Fujita T
    • Journal Title

      Hypetens Res 28

      Pages: 1009-1015

    • NAID

      10017403750

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Mechanical stretch activates angiotensin II type 1 receptor without the involvement of angiotensin II.2004

    • Author(s)
      Y Zou, H Akazawa, Y Qin, H Takano, N Makita, K Iwanaga, W Zhu, H Toko, K Tamura, M Kihara, T Minamino, T Nagai, A Fukamizu, S Umemura, T Iiri, T Fujita, I Komuro
    • Journal Title

      Nature Cell Biol. 6

      Pages: 499-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] Endogenous Adrenomedullin Protects against Vascular Response to Injury in Mice.2004

    • Author(s)
      Kawai J, Ando K, Tojo A, Shimosawa T, Takahashi K, Onozato M, Yamasaki M, Ogita T, Nakaoka T, Fujita T.
    • Journal Title

      Circulation. 109

      Pages: 1147-1153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] Adrenomedullin, an Endogenous Peptide, Counteracts Cardiovascular Damage.2002

    • Author(s)
      Shimosawa T, Shibagaki Y, Ishibashi K, Kitamura K, Kangawa K, Kato S, Ando K, Fujita T.
    • Journal Title

      Circulation 105

      Pages: 106-111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] A G_<sα> mutant activated by Gβγ suggests a molecular mechanism for activation of trimeric G-proteins.2002

    • Author(s)
      P Rondard, T Iiri, S Srinivasan, E Meng, T Fujita, H R Bourne
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 98

      Pages: 6150-6155

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207044
  • [Journal Article] Epigenetic regulation of BMP7 in the regenerative response to ischemia

    • Author(s)
      Marumo T, Hishikawa K, Yoshikawa M, Fujita T.
    • Journal Title

      J Am Sac Nephrol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.

    • Author(s)
      Wang H, Shimosawa T, Matsui H, Kaneko T, Ogura S, Uetake Y, Takenaka K, Yatomi Y, Fujita T
    • Journal Title

      J. Hypertension (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Paradoxical mineralocorticoid receptor activation and left ventricular -diastolic dysfunction under high oxidative stress conditions

    • Author(s)
      Wang H, Shimosawa T, Matsui H, Kaneko T, Ogura S, Uetake Y, Takenaka K, Yatomi Y, Fujita T.
    • Journal Title

      J Hypertension (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Journal Article] Epigenetic regulation of BMP7 in the regenerative response to ischemia.

    • Author(s)
      Marumo T, Hishikawa K, Yoshikawa M, Fujita T
    • Journal Title

      J. Am Soc Nephrol (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Patent] 腎機能の評価方法および糖尿病患者における腎機能が低下した患者の判別方法2020

    • Inventor(s)
      丸茂丈史、藤田敏郎
    • Industrial Property Rights Holder
      国立大学法人 東京大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-150726
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Patent] 腎機能の評価方法および糖尿病患者における腎機能が低下した患者の判別方法2020

    • Inventor(s)
      丸茂丈史、藤田敏郎
    • Industrial Property Rights Holder
      丸茂丈史、藤田敏郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] Klotho 減少は高カリウム血症の原因となりうる2021

    • Author(s)
      河原崎 和歌子,鮎澤 信宏,広浜 大五郎,西本 光宏,大庭 成喜,丸茂 丈史,藤田 敏郎.
    • Organizer
      第67回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 「MRを介した間在細胞 pendrinの制御機構」2021

    • Author(s)
      鮎澤信宏, 河原崎和歌子,大庭成喜,藤田敏郎
    • Organizer
      第67回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 「食塩、高血圧と私」、Homer Smith Award受賞記念講演2021

    • Author(s)
      藤田敏郎
    • Organizer
      第9回臨床高血圧フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] Rac1-ミネラルコルチコイド受容体系活性化は糖尿病性腎臓病進展に寄与する2021

    • Author(s)
      広浜 大五郎,西本 光宏,鮎澤 信宏,河原崎 和歌子,藤井 航,大庭 成喜,柴田 茂,丸茂 丈史,藤田 敏郎
    • Organizer
      第67回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 加齢に伴う高血圧発症機序の解明~食塩の関与~」2021

    • Author(s)
      河原崎和歌子, 鮎澤信宏,大庭成喜,藤田敏郎
    • Organizer
      第67回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 「ライフコースにおける食塩感受性高血圧の発症機序」2021

    • Author(s)
      藤田敏郎
    • Organizer
      第43回日本高血圧学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 加齢に伴う食塩感受性高血圧発症における腎血管性機序の検討2020

    • Author(s)
      河原崎 和歌子, 水野 理介, 西本 光宏, 鮎澤 信宏, 広浜 大五郎, 大庭 成嘉, 丸茂 丈史, 藤田 敏郎.
    • Organizer
      第63回日本腎臓学会総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 食塩による高血圧発症のメカニズム ASN Homer W. Smith Award受賞記念講演2020

    • Author(s)
      藤田敏郎
    • Organizer
      第63回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] ポドサイトRac1-ミネラルコルチコイド受容体(MR)系活性化は糖尿病性腎臓病進展に寄与する.2020

    • Author(s)
      広浜 大五郎, 西本 光宏, 鮎澤 信宏, 河原崎 和歌子, 大庭 成喜, 丸茂 丈史, 藤田 敏郎.
    • Organizer
      第63回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] アルドステロン過剰時のPendrin制御とα-ケトグルタル酸2020

    • Author(s)
      鮎澤 信宏、広浜 大五郎、西本 光宏、河原崎 和歌子、丸茂 丈史、藤田 敏郎.
    • Organizer
      第63回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 新たな糖尿病性腎臓病モデルの開発とミネラルコルチコイド受容体の関与の解明.2020

    • Author(s)
      広浜 大五郎, 西本 光宏, 鮎澤 信宏, 河原崎 和歌子, 大庭 成喜, 丸茂 丈史, 藤田 敏郎.
    • Organizer
      第56回高血圧関連疾患モデル学会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] 糖尿病性腎症に生じたメタボリックメモリー関連遺伝子のDNAメチル化異常.2020

    • Author(s)
      丸茂丈史、星野純一、山内真之、乳原善文、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、藤田敏郎.
    • Organizer
      第63回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K21596
  • [Presentation] "Urinary kidney-specific DNA methylation signature correlates with renal function decline in diabetes"2019

    • Author(s)
      Takeshi Marumo, Daigoro Hirohama, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Wakako Kawarazaki, Shigeyoshi Oba, Toshiro Fujita.
    • Organizer
      American Society of Nephrology, Kidney Week 2019, Washington, DC.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] MR activation by Rac1 in kidney disease2019

    • Author(s)
      Toshiro Fujita
    • Organizer
      The Kidney and Beyond Conference, American Society Physiology (APS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 「老化に伴う食塩感受性高血圧発症機序の解明」2019

    • Author(s)
      河原崎和歌子, 水野理介, 西本光宏, 鮎澤信宏, 広浜大五郎, 森典子, 大庭成喜, 丸茂丈史, 藤田敏郎.
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] 高血圧とエピジェネテイクス~食塩感受性高血圧~2019

    • Author(s)
      藤田敏郎
    • Organizer
      第93回日本内分泌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 「ミネラロコルチコイド過剰による食塩感受性高血圧におけるPendrin活性化機構」2019

    • Author(s)
      鮎澤 信宏、広浜 大五郎、西本 光宏、河原崎 和歌子、丸茂 丈史、藤田 敏郎.
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] 高血圧とエピジェネティクス~食塩と高血圧~2019

    • Author(s)
      藤田敏郎
    • Organizer
      Research PlaNet 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Aldosterone-independent mineralocorticoid receptor in salt-sensitive hypertension and glomerular diseases2019

    • Author(s)
      Toshiro Fujita
    • Organizer
      International Symposium for Aldosterone and Related Substances in Hypertension 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Homer Smith Award Lecture, ‘Salt, Hypertension and the Kidneys’, American Society of Nephrology,2019

    • Author(s)
      Toshiro Fujita.
    • Organizer
      American Society of Nephrology, Kidney Week 2019, Washington, DC.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Importance of dietary salt intake for the efficacy of mineralocorticoid receptor blockade against ACEI/ARB-resistant albuminuria: -a sub-analysis of EVALUATE study-.2019

    • Author(s)
      Mitsuhiro Nishimoto, Hiroshi Ohtsu, Takeshi Marumo, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Toshiro Fujita.
    • Organizer
      International Symposium of Aldosterone and Related Substances in Hypertension 2019, Sendai
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] "The mineralocorticoid receptor antagonist Finerenone limits podocyte injury in high-salt loaded db/db mice"2019

    • Author(s)
      Daigoro Hirohama, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Wakako Kawarazaki, Shigeyoshi Oba, Takeshi Marumo, Toshiro Fujita.
    • Organizer
      American Society of Nephrology, Kidney Week 2019, Washington, DC.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Two distinct regulations of pendrin by mineralocorticoid receptor in distal nephron2019

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Wakako Kawarazaki, Takeshi Marumo, Toshiro Fujita
    • Organizer
      The 44th International Aldosterone Conference,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 「加齢に伴う食塩感受性高血圧発症機序の解明」2019

    • Author(s)
      河原崎和歌子, 水野理介, 西本光宏, 鮎澤信宏, 広浜大五郎, 大庭成喜, 丸茂丈史, 藤田敏郎.
    • Organizer
      第42回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Two different mechanism of pendrin regulation by mineralocorticoid receptor in distal nephron.2019

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Wakako Kawarazaki, Takeshi Marumo, Toshiro Fujita.
    • Organizer
      International Symposium of Aldosterone and Related Substances in Hypertension 2019, Sendai
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Two distinct regulations of pendrin by mineralocorticoid receptor in distal nephron2019

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Wakako Kawarazaki, Takeshi Marumo, Toshiro Fujita
    • Organizer
      The 44th International Aldosterone Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Homer W. Smith Award Lecture “Salt, hypertension and the kidneys”2019

    • Author(s)
      Toshiro Fujita
    • Organizer
      American Society of Nephrology, Kidney Week 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed salt-sensitive hypertension2019

    • Author(s)
      Toshiro Fujita
    • Organizer
      International symposium on Epigenome 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 「加齢に伴う食塩感受性高血圧発症機序の解明」2019

    • Author(s)
      河原崎和歌子, 水野理介, 西本光宏, 鮎澤信宏, 広浜大五郎, 大庭成喜, 丸茂丈史, 藤田敏郎.
    • Organizer
      第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会合同学会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] 「エピジェネティック尿検査による糖尿病性腎症悪化の診断」2019

    • Author(s)
      丸茂丈史、星野純一、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、佐藤敦久、乳原善文、下澤達雄、藤田敏郎.
    • Organizer
      第42回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018

    • Author(s)
      広浜 大五郎、鮎澤 信宏、上田 浩平、西本 光宏、河原崎 和歌子、下澤 達雄、丸茂 丈史、柴田 茂、藤田 敏郎
    • Organizer
      第22回日本心血管内分泌代謝学会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018

    • Author(s)
      広浜 大五郎, 鮎澤 信宏, 西本 光宏, 河原崎 和歌子, 下澤 達雄, 丸茂 丈史, 柴田 茂, 藤田 敏郎
    • Organizer
      第54回高血圧関連疾患学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢に伴う食塩感受性高血圧発症機序の検討2018

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、丸茂丈史、藤田敏郎
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] エピゲノム情報に基づく新しい腎臓病治療2018

    • Author(s)
      藤田敏郎、丸茂丈史
    • Organizer
      第61回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢に伴う食塩感受性高血圧発症におけるKlotho-Wnt-Rho pathwayの関与2018

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、森典子、大庭成喜、丸茂丈史、藤田敏郎
    • Organizer
      第41回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 食塩と高血圧研究の進歩~エピジェネティクス~2018

    • Author(s)
      藤田敏郎
    • Organizer
      第41回日本高血圧学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] The mechanism of Salt&shy;sensitive Hypertension in Intermittent Hypoxia2018

    • Author(s)
      Alimila Yeerbolati, Sayoko Ogura, Latapati Reheman, Conghui Wang, Beibei Liu, Ichiro Kuwahira, Mikiyasu Shirai, Tatsuo Shimosawa, Toshiro Fujita
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Aldosterone Is Essential for Angiotensin II-Induced Activation of Pendrin2018

    • Author(s)
      Fujita T
    • Organizer
      2018 International Society of Hypertension (ISH) Satellite Symposium Renin-Angiotensin-Aldosterone System (RAAS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Dysregulation of the ubiquitin ligase component kelch-like 3 causes Na-Cl cotransporter activation and salt retention in obese diabetic mice2018

    • Author(s)
      Kenichi Ishizawa, Qin Wang, Jinping Li, Ning Xu, Yoshikazu Nemoto, Chikayuki Morimoto, Toshiro Fujita, Shunya Uchida, Shigeru Shibata
    • Organizer
      ASN Kidney Week 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢に伴う食塩感受性高血圧発症におけるKlotho-Wnt-Rho pathwayの関与2018

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、森典子、大庭成喜、丸茂丈史、藤田敏郎
    • Organizer
      第41回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Oxidative stress causes salt sensitive hypertension via activation of Na+-Cl-cotransporter (ncc)2018

    • Author(s)
      Wang C, Shimosawa T, Reheman L, Koid S S, Yeerbolati A, Liu B, Mori F, Fujita T
    • Organizer
      Joint Hypertension Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎臓特異的DNAメチル化を尿中マーカーとした糖尿病性腎症の尿細管障害診断法2018

    • Author(s)
      丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、佐藤敦久、渥美義仁、星野純一、乳原善文、藤田敏郎
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018

    • Author(s)
      広浜 大五郎, 鮎澤 信宏, 西本 光宏, 河原崎 和歌子, 下澤 達雄, 丸茂 丈史, 柴田 茂, 藤田 敏郎
    • Organizer
      第41回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
    • Organizer
      Gordon Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎臓特異的DNAメチル化を尿中マーカーとした糖尿病性腎症の尿細管障害診断法2018

    • Author(s)
      丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、佐藤敦久、渥美義仁、星野純一、乳原善文、藤田敏郎
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Mineralocorticoid receptor in renal intercalated cells mediates RAAS-driven pendrin regulation to maintain fluid homeostasis2018

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita.
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018

    • Author(s)
      Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
    • Organizer
      International Aldosterone Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] High salt diet increases Prostaglandin E2 synthesis through oxidative stress2018

    • Author(s)
      Reheman Latapati, 森典子, 広浜大五郎, 小倉彩世子, 王聡慧, Alimila Yeerbolati, Liu Beibei, 藤田敏郎, 矢冨裕, 下澤達雄
    • Organizer
      第22回日本心血管内分泌代謝学会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢に伴う食塩感受性高血圧発症機序の検討2018

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、丸茂丈史、藤田敏郎
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Pendrinの血圧・水電解質代謝調節作用に関する検討2018

    • Author(s)
      広浜 大五郎、鮎澤 信宏、上田 浩平、西本 光宏、河原崎 和歌子、下澤 達雄、丸茂 丈史、柴田 茂、藤田 敏郎
    • Organizer
      第22回日本心血管内分泌代謝学会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Pendrinの血圧・電解質代謝調節作用に関する役割2018

    • Author(s)
      広浜 大五郎, 鮎澤 信宏, 西本 光宏, 河原崎 和歌子, 下澤 達雄, 丸茂 丈史, 柴田 茂, 藤田 敏郎
    • Organizer
      第41回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] RAAS-driven pendrin regulation to maintain fluid homeostasis2018

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
    • Organizer
      第61回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] Mineralocorticoid receptor in renal intercalated cells mediates pendrin regulation by renin-angiotensin-aldosterone system to maintain fluid homeostasis2018

    • Author(s)
      Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Wakako Kawarazaki, Tastuo Shimosawa, Takeshi Marumo, Toshiro Fujita
    • Organizer
      Gordon Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] エピゲノム情報に基づく新しい腎臓病治療2018

    • Author(s)
      藤田敏郎、丸茂丈史
    • Organizer
      第61回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19533
  • [Presentation] 食塩と高血圧研究の進歩~エピジェネティクス~2018

    • Author(s)
      藤田敏郎
    • Organizer
      第41回日本高血圧学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2018

    • Author(s)
      Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
    • Organizer
      International Aldosterone Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017

    • Author(s)
      広浜 大五郎、 柴田 茂、上田 浩平、鮎澤 信宏、西本 光宏、河原崎 和歌子、渡邉 篤史、下澤 達雄、丸茂 丈史、藤田 敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017

    • Author(s)
      河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
    • Organizer
      第60回日本腎臓学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017

    • Author(s)
      渡邉篤史 丸茂丈史 河原崎和歌子 西本光宏 鮎澤信宏 広浜大五郎 上田浩平 熊谷裕生 藤田敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 高血圧とエピジェネティクス~妊娠時低栄養による食塩感受性高血圧発症の中枢神経機序の解明~2017

    • Author(s)
      森典子、西本光宏、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017

    • Author(s)
      Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
    • Organizer
      American Society of Nephrology Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2017

    • Author(s)
      広浜 大五郎、 柴田 茂、上田 浩平、鮎澤 信宏、西本 光宏、河原崎 和歌子、渡邉 篤史、下澤 達雄、丸茂 丈史、藤田 敏郎
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢と食塩感受性高血圧~抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する~2017

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017

    • Author(s)
      西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
    • Organizer
      第90回日本内分泌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017

    • Author(s)
      丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 加齢と食塩感受性高血圧~抗加齢因子Klothoの発現低下はRhoA活性化による血管収縮を惹起する~2017

    • Author(s)
      河原崎和歌子、水野理介、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 高血圧とエピジェネティクス~妊娠時低栄養による食塩感受性高血圧発症の中枢神経機序の解明~2017

    • Author(s)
      森典子、西本光宏、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎pendrinの発現機構と 血圧調節における役割の解明2017

    • Author(s)
      広浜 大五郎、鮎澤 信宏、上田 浩平、西本 光宏、河原崎 和歌子、渡邉 篤史、下澤 達雄、丸茂 丈史、柴田 茂、藤田 敏郎
    • Organizer
      第21回心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 抗加齢因子Klothoの発現低下は腎mTORC1の活性化を介して食塩感受性高血圧を惹起する2017

    • Author(s)
      河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、丸茂丈史、藤田敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Aldosterone is essential for angiotensin II-induced upregulation of pendrin2017

    • Author(s)
      Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto,Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita
    • Organizer
      American Society of Nephrology Kidney Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017

    • Author(s)
      鮎澤 信宏、上田 浩平、広浜 大五郎、西本 光宏、河原崎 和歌子、渡邉 篤史、丸茂 丈史、藤田 敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017

    • Author(s)
      上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 腎間在細胞ミネラロコルチコイド受容体欠損マウスを用いたPendrin制御機構の解析2017

    • Author(s)
      鮎澤 信宏、上田 浩平、広浜 大五郎、西本 光宏、河原崎 和歌子、渡邉 篤史、丸茂 丈史、藤田 敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎臓特異的な11beta HSD2活性低下による高血圧発症機序の解析2017

    • Author(s)
      上田浩平、西本光宏、広浜大五郎、鮎澤信宏、河原崎和歌子、渡邉篤史、下澤達雄、丸茂丈史、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎pendrinの発現機構と 血圧調節における役割の解明2017

    • Author(s)
      広浜 大五郎、鮎澤 信宏、上田 浩平、西本 光宏、河原崎 和歌子、渡邉 篤史、下澤 達雄、丸茂 丈史、柴田 茂、藤田 敏郎
    • Organizer
      第21回心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Activation of mineralocorticoid receptor in CKD and salt-sensitive hypertension2017

    • Author(s)
      Fujita T
    • Organizer
      American Society of Nephrology Renal Week 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病腎メサンギウム細胞のDNAメチル化異常によるTGFb発現増加をRA系阻害薬は抑制する2017

    • Author(s)
      大庭成喜、広浜大五郎、鮎澤信宏、西本光宏、河原崎和歌子、上田浩平、下澤達雄、丸茂丈史、藤田敏郎
    • Organizer
      第40回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病性腎症でエピゲノム異常をきたす核内受容体PXRは腎糖新生を調整する2017

    • Author(s)
      渡邉篤史 丸茂丈史 河原崎和歌子 西本光宏 鮎澤信宏 広浜大五郎 上田浩平 熊谷裕生 藤田敏郎
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 特異的DNAメチル化signatureを用いた糖尿病性腎症の尿細管障害診断2017

    • Author(s)
      丸茂丈史、下澤達雄、河原崎和歌子、西本光宏、鮎澤信宏、広浜大五郎、上田浩平、渡邉篤史、星野純一、乳原善文、藤田敏郎
    • Organizer
      第60回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017

    • Author(s)
      Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
    • Organizer
      AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 食塩感受性高血圧の内分泌学的および腎生理学的検討2017

    • Author(s)
      西本光宏、上田浩平、河原崎和歌子、水野理介、森典子、渡邉篤史、広浜大五郎、鮎澤信宏、大庭成喜、丸茂丈史、藤田敏郎
    • Organizer
      第90回日本内分泌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Systemic effect of renal 11beta-HSD2 deficiency on blood pressure regulation2017

    • Author(s)
      Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita
    • Organizer
      AHA Council on Hypertension American Society of Hypertension Joint Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Aldosterone antagonists for the treatment of hypertensive nephropathy2016

    • Author(s)
      Fujita T
    • Organizer
      International Society of Hypertension
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016

    • Author(s)
      鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-19
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] The mechanism of blood pressure elevation in distal nephron-specific Hsd11b2 knockout mice2016

    • Author(s)
      Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Nobuhiro Ayuzawa, Daigoro Hirohama, Atsushi Watanabe, Takeshi Marumo, Toshiro Fujita
    • Organizer
      The 41st International Aldosterone Conference Aldosterone and Mineralocorticoids
    • Place of Presentation
      Boston, USA
    • Year and Date
      2016-03-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Role of aldosterone and aldosterone receptor in mediating salt sensitive hypertension2016

    • Author(s)
      Fujita T
    • Organizer
      International Society of Hypertension
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎臓エピゲノム情能に基づく生活習慣病に対する治療戦略2016

    • Author(s)
      丸茂丈史, 藤田敏郎
    • Organizer
      第39回日本高血圧学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-30
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016

    • Author(s)
      河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-19
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] 抗加齢因子Klotho発現低下に伴う食塩感受性高血圧発症機序の解明2016

    • Author(s)
      河原崎和歌子, 丸茂丈史, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 渡邉篤史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Salt-induced activation of Rac1-MR pathway in salt-sensitive hypertension and chronic kidney disease2016

    • Author(s)
      Fujita T
    • Organizer
      RAAS symposium at the satellite symposium of ISH
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 腎臓エピゲノム情能に基づく生活習慣病に対する治療戦略2016

    • Author(s)
      丸茂丈史, 藤田敏郎
    • Organizer
      第39回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病性腎症で核内受容体PXRはエピジェネティクス異常をきたし線維化因子RGC32を増加させる2016

    • Author(s)
      渡邉篤史, 丸茂丈史, 河原崎和歌子, 西本光宏, 鮎澤信宏, 広浜大五郎, 上田浩平, 熊谷裕生, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] The mechanism of salt sensitive hypetension in intermittent hypoxia.2016

    • Author(s)
      Yeerbolati A, Ogura S, Reheman L, Wang C, Liu B, Kuwahira I, Shirai M, Shimosawa T, Fujita T
    • Organizer
      The 26th Scientific meeting of the International Society of Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016

    • Author(s)
      広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 間在細胞EGFP標識マウスを用いた間在細胞分取・解析法の確立2016

    • Author(s)
      鮎澤信宏, 上田浩平, 広浜大五郎, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] PendrinとNCC発現調節におけるアンジオテンシンIIとアルドステロンの異なる役割2016

    • Author(s)
      広浜大五郎, 柴田茂, 上田浩平, 鮎澤信宏, 西本光宏, 河原崎和歌子, 渡邉篤史, 丸茂丈史, 藤田敏郎
    • Organizer
      第59回 日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-06-19
    • Data Source
      KAKENHI-PROJECT-16K15494
  • [Presentation] Renal mechanism of Salt-sensitive Hypertension2016

    • Author(s)
      Fujita T
    • Organizer
      Third Guangzhou International Forum in Hypertension Research
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Salt, Aldosterone and Hypertension2015

    • Author(s)
      藤田敏郎
    • Organizer
      Asian Pacific Society of Hypertension
    • Place of Presentation
      Bali
    • Year and Date
      2015-06-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] Activation of Mineralocorticoid Receptor in Salt-Sensitive Hypertension &#8211;From Bench to Clinic2015

    • Author(s)
      藤田敏郎
    • Organizer
      Oriental Congress of Cardiology
    • Place of Presentation
      上海
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] “IMPORTANCE OF DIETARY SALT INTAKE IN ANTI-ALBUMINURIC EFFECT OF AN ALDOSTERONE BLOCKER2015

    • Author(s)
      藤田敏郎
    • Organizer
      European Society of Hypertension
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2015-05-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] 生活習慣病とエピジェネティクス2015

    • Author(s)
      藤田敏郎
    • Organizer
      DOHAD研究会
    • Place of Presentation
      東京 昭和大学
    • Year and Date
      2015-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] “Salt, Aldosterone and Hypertension” and “Potassium, Hypertension and Vascular disease”2015

    • Author(s)
      藤田敏郎
    • Organizer
      Asian Pacific Society of Hypertension
    • Place of Presentation
      Bali
    • Year and Date
      2015-06-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Mineralocorticoid receptor and salt-sensitive hypertension2015

    • Author(s)
      藤田敏郎
    • Organizer
      International Symposium and Annual ADMIRE Cost Meeting
    • Place of Presentation
      Zermatt, Switzerland
    • Year and Date
      2015-10-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病性腎症にみられるエピジェネティック異常は血糖治療に抵抗性を示す2015

    • Author(s)
      丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、上田浩平、菱川慶一、櫻井裕之、藤田敏郎
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] Mechanism of Salt-sensitive hypertension2015

    • Author(s)
      藤田敏郎
    • Organizer
      American Heart Association
    • Place of Presentation
      Orland
    • Year and Date
      2015-11-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] 生活習慣病とエピジェネティクス2015

    • Author(s)
      藤田敏郎
    • Organizer
      DOHAD研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Activation of mineralocorticoid receptor in the heart and the kidney2015

    • Author(s)
      藤田敏郎
    • Organizer
      Chinese Academy of Sciences
    • Place of Presentation
      上海
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Mineralocorticoid receptor and salt-sensitive hypertension2015

    • Author(s)
      藤田敏郎
    • Organizer
      International Symposium and Annual ADMIRE Cost Meeting
    • Place of Presentation
      Zermatt, Switzerland
    • Year and Date
      2015-10-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] 日本医師会医学賞受賞講演「高血圧の発症の分子メカニズム」2015

    • Author(s)
      藤田敏郎
    • Organizer
      日本医師会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 遠位ネフロン特異的Rac1欠損マウスを用いたRac1-ミネラロコルチコイド受容体(MR)経路の解析2015

    • Author(s)
      鮎澤 信宏、上田 浩平、広浜 大五郎、西本 光宏、河原崎 和歌子、渡邉 篤史、丸茂 丈史、藤田 敏郎
    • Organizer
      第58回 日本腎臓学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Eplerenoneは塩分過剰摂取によるRA系阻害抵抗性腎障害を抑制する&#8722;EVALUATE試験サブ解析&#8722;2015

    • Author(s)
      西本光宏、大津洋、丸茂丈史、河原崎和歌子、鮎澤信宏、上田浩平、広浜大五郎、渡邉篤史、藤田敏郎
    • Organizer
      第58回 日本腎臓学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease.2015

    • Author(s)
      Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
    • Organizer
      Kidney Week 2015 ASN Annual Meeting
    • Place of Presentation
      San Diego Convention Center, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] Activation of Mineralocorticoid Receptor in Salt-Sensitive Hypertension &#8211;From Bench to Clinic2015

    • Author(s)
      藤田敏郎
    • Organizer
      Oriental Congress of Cardiology
    • Place of Presentation
      上海
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Epigenetic abnormalities underlie increased expression of nuclear receptor PXR in diabetic kidney disease2015

    • Author(s)
      Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Kohei Ueda, Hiroo Kumagai, Toshiro Fujita
    • Organizer
      Kidney Week 2015 ASN Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] Mechanism of Salt-sensitive hypertension2015

    • Author(s)
      藤田敏郎
    • Organizer
      American Heart Association
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-11-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05788
  • [Presentation] 糖尿病性腎症にみられる治療抵抗性エピジェネティック異常2014

    • Author(s)
      丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、渡邉篤史、菱川慶一、櫻井裕之、藤田敏郎
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-07-04
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] Interactions between Sodium and Potassium on blood pressure and cardiovascular disease2014

    • Author(s)
      Fujita T.
    • Organizer
      at Asian Pacific Congress of Hypertension (APCH)
    • Place of Presentation
      Cebu city, Philippines
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The Mechanism for Activation of Mineralocorticoid Receptor in the Heart and Kidney2014

    • Author(s)
      Fujita T.
    • Organizer
      Gordon Research Conference"The Renin-Angiotensin System Beyond Angiotensin II"
    • Place of Presentation
      Lucca (Barga), Italy(Keynote Lecture)
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] 糖尿病性腎症にみられる治療抵抗性DNAメチル化異常2014

    • Author(s)
      丸茂丈史、八木慎太郎、河原崎和歌子、西本光宏、鮎澤信宏、上田浩平、渡邉篤史、藤田敏郎
    • Organizer
      第6回腎疾患と高血圧研究会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-12
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] The Mechanism for Activation of Mineralocorticoid Receptor in the Heart and Kidney2014

    • Author(s)
      Fujita T
    • Organizer
      Gordon Research Conference "The Renin-Angiotensin System Beyond Angiotensin II"
    • Place of Presentation
      Keynote Lecture
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The Mechanism for Activation of Mineralocorticoid Receptor in the Heart and Kidney2014

    • Author(s)
      Fujita T
    • Organizer
      Gordon Research Conference “The Renin-Angiotensin System Beyond Angiotensin II”
    • Place of Presentation
      Lucca (Barga), Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The Mechanism for Activation of Mineralocorticoid Receptor in the Heart and Kidney2014

    • Author(s)
      Fujita T
    • Organizer
      Gordon Research Conference “The Renin-Angiotensin System Beyond Angiotensin II”
    • Place of Presentation
      Lucca (Barga), Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The kidney and hypertension : The pathogenesis of Salt-Sensitive Hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The kidney and hypertension: The pathogenesis of Salt-Sensitive Hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Hong Kong, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Epigenetics in salt-sensitive hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      8th annual Winter Research Meeting on Translational Basic Science, European Society of Cardiology
    • Place of Presentation
      Les Diablerets- Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] "Honorary Membership Award"and Lecture"The pathogenesis of Salt-sensitive hypertension"2013

    • Author(s)
      Fujita T.
    • Organizer
      at Working group of kidney at ESH meeting
    • Place of Presentation
      Milan on
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Mineralocorticoid Receptor2013

    • Author(s)
      Fujita T
    • Organizer
      Cardiovascular Seminar "Fundamental Mechanisms of Hypertension", American Heart association (AHA)
    • Place of Presentation
      Dallas, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Salt, obesity and hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      The 5th Pulse of Asia
    • Place of Presentation
      Soel, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Salt, obesity and hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      The 5th Pulse of Asia
    • Place of Presentation
      Seol, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The pathogenesis of Salt-sensitive hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      Working group of kidney at ESH meeting
    • Place of Presentation
      Milan, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Rac1-mediated Activation of Mineralocorticoid Receptor in Pressure Overloaded Heart2013

    • Author(s)
      Ayuzawa N, Nagase M, Fujita T. et al
    • Organizer
      39th Meeting of the International Aldosterone Conference
    • Place of Presentation
      San Francisco, CA, USA (Young Investigator Award(YIA)
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Epigenetics in salt-sensitive hypertension2013

    • Author(s)
      Fujita T.
    • Organizer
      at the 8th annual Winter Research Meeting on Translational Basic Science, European Society of cardiology
    • Place of Presentation
      Les Diablerets- Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Epigenetic mechanism on hypertension-The vascular road to heart failure at 20132013

    • Author(s)
      Fujita T
    • Organizer
      2013 HFA Winter Research meeting ESH on translational Research
    • Place of Presentation
      Les Diablerets, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Mineralocorticoid Receptor2013

    • Author(s)
      Fujita T.
    • Organizer
      at Cardiovascular Seminar"Fundamental Mechanisms of Hypertension", American Heart association (AHA)
    • Place of Presentation
      Dallas, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Chairperson at Basic and Clinical Science"Flipping the Switch : Small GTPases in CKD"2013

    • Author(s)
      Fujita T.
    • Organizer
      at American Society of Nephrology (ASN)
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The kidney and hypertension : The pathogenesis of Salt-Sensitive Hypertension2013

    • Author(s)
      Fujita T.
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Hong Kong(Plenary Lecture)
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Salt, obesity and hypertension2013

    • Author(s)
      Fujita T.
    • Organizer
      at The 5th Pulse of Asia
    • Place of Presentation
      Seol, Korea(Plenary Lecture)
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The kidney and hypertension: The pathogenesis of Salt-Sensitive Hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      World Congress of Nephrology
    • Place of Presentation
      Hong Kong, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Epigenetics in salt-sensitive hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      8th annual Winter Research Meeting on Translational Basic Science
    • Place of Presentation
      Les Diablerets- Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The Mechanism of salt-sensitive hypertension,salt, obesity and hypertension2013

    • Author(s)
      Fujita T.
    • Organizer
      at Ruijin Hospital (Prof. Pingjin Gao, Shanghai Jiaotong University, School of Medicine),at the 7th Oriental Congress of cardiology(OCC)
    • Place of Presentation
      Shanghai, China
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Salt, obesity and hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      The 5th Pulse of Asia
    • Place of Presentation
      Plenary Lecture
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The pathogenesis of Salt-sensitive hypertension2013

    • Author(s)
      Fujita T
    • Organizer
      Working group of kidney at ESH meeting
    • Place of Presentation
      Milan, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Activation of Rac1-mineralocorticoid pathway in proteinuric kidney disease2012

    • Author(s)
      Fujita T
    • Organizer
      9th International Podocyte Conference
    • Place of Presentation
      Miami, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Activation of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      45th annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The Pathogenesis of Salt-Sensitive Hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      International Society of Hypertension (ISH)
    • Place of Presentation
      Sydney
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Activation of Rac1-mineralocorticoid pathway in proteinuric kidney disease2012

    • Author(s)
      Fujita T
    • Organizer
      9th International Podocyte Conference
    • Place of Presentation
      Miami, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Rac1-MR activation in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      satellite meeting of ISH 2012
    • Place of Presentation
      Palm Cove, Queensland, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] 腎上皮由来、メサンギウム細胞由来iPS 細胞を使ったEpigenetic Memoryからの腎臓再生の可能性について2012

    • Author(s)
      高瀬敦、菱川慶一、出射真奈、藤田敏郎
    • Organizer
      日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-01
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      24th Scientific Meeting of the International Society of Hypertension (ISH)
    • Place of Presentation
      Sydbey, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Role of Sympathetic nervous system in salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      at the satellite meeting of ISH 2012:"The neuropathophysiology of hypertension-an emerging therapeutic target"
    • Place of Presentation
      Palm Cove, Queensland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Activation of Rac1-mineralocorticoid pathway in proteinuric kidney disease2012

    • Author(s)
      Fujita T.
    • Organizer
      at the 9th International Podocyte Conference
    • Place of Presentation
      Miami, Florida USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      the 22nd European Society of Hypertension (ESH)
    • Place of Presentation
      London, United Kingdom
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      at the 24th Scientific Meeting of the International Society of Hypertension (ISH)
    • Place of Presentation
      Sydney(Plenary lecture)
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Activation of Rac1-MR pathway in Salt-Sensitive Hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      American Society of Nephrology (ASN)
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Role of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      at European Section of Aldosterone Council
    • Place of Presentation
      Hannover, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Role of Sympathetic nervous system in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      satellite meeting of ISH 2012
    • Place of Presentation
      Palm Cove, Queensland, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Role of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      European Section of Aldosterone Council
    • Place of Presentation
      Hannover, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Activation of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      at the 45th annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, US(Symposium lecture)
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Activation of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      45th annual meeting of American Society of Nephrology
    • Place of Presentation
      San Diego, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      22nd European Society of Hypertension
    • Place of Presentation
      London, United Kingdom
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Role of Rac1-MR pathway in salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      European Section of Aldosterone Council
    • Place of Presentation
      Hannover, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      24th Scientific Meeting of the International Society of Hypertension (ISH)
    • Place of Presentation
      Sydney, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Rac1-MR activation in salt-sensitive hypertension2012

    • Author(s)
      Fujita T.
    • Organizer
      at the satellite meeting of ISH 2012:"Aldosterone and salt : Heart and kidney"
    • Place of Presentation
      Palm Cove Queensland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] The mechanism of salt-sensitive hypertension2012

    • Author(s)
      Fujita T
    • Organizer
      22nd European Society of Hypertension (ESH)
    • Place of Presentation
      London, United Kingdom
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659410
  • [Presentation] Epigenetic Memoryからの腎臓由来iPS細胞を利用した腎臓再生医療の試み2012

    • Author(s)
      高瀬敦、菱川慶一、藤田敏郎、高戸毅
    • Organizer
      日本再生医療学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-14
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Presentation] Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes : role of small GTPase Rac12011

    • Author(s)
      Nagase M, Fujita T. et al
    • Organizer
      High Blood Pressure Research
    • Place of Presentation
      Florida, USA (oral)
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Activation of the Racl-MR Pathway in Saltsensitive Hypertension2011

    • Author(s)
      藤田敏郎
    • Organizer
      High Blood Presssure Research 2011 Scientific Sessions
    • Place of Presentation
      Walt Disney World Dolph in Resort, Florida, USA(招待講演)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] 腎臓由来iPS細胞の分化誘導の可能性について2011

    • Author(s)
      高瀬敦、菱川慶一、出射真奈、藤田敏郎
    • Organizer
      日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Presentation] Aberrant Renal be-ta-adrenergic-WNK4 Pathway in Salt-sensitive Hypertension2011

    • Author(s)
      藤田敏郎
    • Organizer
      High Blood Presssure Research 2011 Scientific Sessions
    • Place of Presentation
      Walt Disney World Dolph in Resort, Florida, USA(招待講演)
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] ヒト腎臓由来iPS細胞のDNAメチル化プロファイルと細胞記憶2011

    • Author(s)
      菱川慶一、高瀬敦、吉川真弘、出射真奈、藤田敏郎
    • Organizer
      日本腎臓学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591184
  • [Presentation] ヒト腎臓由来iPS細胞のDNAメチル化プロファイルと細胞記憶2011

    • Author(s)
      菱川慶一、高瀬敦、出射真奈、藤田敏郎
    • Organizer
      日本腎臓学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591183
  • [Presentation] Pathogenesis of salt-sensitive hypertension2011

    • Author(s)
      藤田敏郎
    • Organizer
      American Society of Nephrology Kidney Week 2011
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, USA(招待講演)
    • Year and Date
      2011-11-10
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] ヒト iPS 細胞における NF-kappaB制御分化誘導の解明2010

    • Author(s)
      高瀬敦、 菱川慶一、上浦望、出射真奈、 藤田敏郎
    • Organizer
      日本腎臓学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Presentation] Activation of mineralocorticoid receptor in hypertension and metabolic syndrome2010

    • Author(s)
      Toshiro Fujita
    • Organizer
      European Society of Hypertension
    • Place of Presentation
      Oslo, Norway
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] iPS細胞における未分化維持機構へのNF-kappaBの役割2010

    • Author(s)
      高瀬敦、 菱川慶一、上浦望、出射真奈、 藤田敏郎
    • Organizer
      日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-22590878
  • [Presentation] 教育講「食塩と高血圧」2010

    • Author(s)
      藤田敏郎
    • Organizer
      第53回日本腎臓学会学術総会
    • Place of Presentation
      神戸国際会議揚、兵庫県
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] 栄誉賞受賞講演 「食塩感受性高血圧の発症機序に関する研究2010

    • Author(s)
      藤田敏郎
    • Organizer
      日本高血圧学会
    • Place of Presentation
      福岡国際会議場、福岡県
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Salt, obesity and hypertension2010

    • Author(s)
      Toshiro Fujita
    • Organizer
      American Society of Hypertension
    • Place of Presentation
      New York, USA
    • Year and Date
      2010-05-02
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Salt, hypertension and metabolic syndrome2010

    • Author(s)
      Toshiro Fujita
    • Organizer
      International Society of Hypertension
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] Eplerenone down-regulaes caveolin-1and improves endothelial function bymechanisms independent of Mrantagonism2009

    • Author(s)
      Muto-A, Isshiki M, Nishimoto-M, Fujita T.
    • Organizer
      The 2^<nd>International Aldosterone Forum in Japan(Award winners' oral presentation)
    • Place of Presentation
      東京
    • Year and Date
      2009-05-17
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] 低用量エプレレノンはMR 非依存的に内皮機能を改善する2009

    • Author(s)
      武藤明子, 一色政志, 西本光宏, 藤田敏郎
    • Organizer
      日本内分泌学会
    • Place of Presentation
      前橋
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] the Arthur C. Corcoran Memorial Lecture : Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome2009

    • Author(s)
      Fujita T
    • Organizer
      the 63rd High Blood Pressure Conference
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-09-24
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] エプレレノンによる肥満高血圧ラットの血管内皮機能改善とその機序2008

    • Author(s)
      武藤明子、一色政志、西本光宏、藤田敏郎
    • Organizer
      日本内分泌学会
    • Place of Presentation
      青森
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] エプレレノンによるメタボリックシンドロームラットの血管内皮機能改善とその機序2008

    • Author(s)
      武藤明子、一色政志、西本光宏、藤田敏郎
    • Organizer
      日本高血圧学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] Low-dose eplerenone down-regulatescaveolin-1 and improves endothelialfunction by mechanisms independent of Mrantagonism2008

    • Author(s)
      Mutoh-A, Isshiki M. and Fujita T.
    • Organizer
      AHA Scientific Sessions 2008 (oralpresentation)
    • Place of Presentation
      ニューオーリンズ、米国
    • Year and Date
      2008-11-10
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] アルドステロンはリガンド刺激によるeNOSリン酸化の増強を介して血管内皮NO 産生を亢進する2007

    • Author(s)
      武藤明子, 高良洋平, 一色政志, 藤田敏郎
    • Organizer
      日本高血圧学会
    • Place of Presentation
      那覇
    • Year and Date
      2007-10-26
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] Role of Kynurenic Aminotransferase-1 Gene in Rostral Ventrolateral Medulla(RVLM)op Salt-Sensitive Hypertension2007

    • Author(s)
      Satoru Ito, Kazutoshi Komatsu, Yoshiharu Yajima, Yoko Iizuka, Takanari Gotoda.Toshiro Fuiita.
    • Organizer
      61st High Blood Pressure Council Anuual Scientific Meeting.
    • Place of Presentation
      Tucson,Arizona,U.S.A
    • Year and Date
      2007-09-26
    • Data Source
      KAKENHI-PROJECT-17209034
  • [Presentation] LOX-1 upregulation shifts endocytosisof cholera toxin from caveolae-mediated tononcaveolae-mediated pathway inendothelial cells2007

    • Author(s)
      Mutoh-A, Isshiki and M. Fujita T.
    • Organizer
      AHA Scientific Sessions 2007(poster presentation)
    • Place of Presentation
      オーランド、米国
    • Year and Date
      2007-11-08
    • Data Source
      KAKENHI-PROJECT-19590852
  • [Presentation] Plenary lecture ”Renal Mechanisms of Salt-Sensitive Hypertension”

    • Author(s)
      藤田敏郎
    • Organizer
      International Society of Nephrology (ISN) NEXUS Symposium
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2014-09-25 – 2014-09-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] STIM1 regulates blood pressure via NO production in vascular endothelial cells

    • Author(s)
      Mitsuhiro Nishimoto, Masashi Isshiki, Risuke Mizuno, Toshiro Fujita
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      京都
    • Year and Date
      2014-04-14 – 2014-04-17
    • Data Source
      KAKENHI-PROJECT-26670426
  • [Presentation] The Antialbuminuric Effects of an Aldosterone Blocker in Hypertensive Patients with Albuminuria: A Double-Blinded, Randomized, Placebo-Controlled (EVALUATE) Trial

    • Author(s)
      Fujita T., Uchida S., Seki G. and Kaname S.
    • Organizer
      American Society of Nephrology Kidney Week 2013
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-21229012
  • [Presentation] 蛋白尿による腎障害メカニズム(尿細管障害)

    • Author(s)
      高瀬  敦、林 松彦、Richard J. Quigg、藤田 敏郎、南学 正臣、菱川 慶一
    • Organizer
      第57回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜 会議センター
    • Year and Date
      2014-07-04 – 2014-07-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461208
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